Con-current Oral Abstract Presentations Session 8
Saturday, April 24, 2010, 3:45 pm - 5:45 pm
Applications of Nanomaterials in Medicine II (Symposia)
293
Biomaterials for Image-Guided Drug Delivery
K. Ferrara;
UC Davis, Davis, CA.
294
Tracking, Modeling and Predicting the Erosion of Fluorescently Labeled Materials Noninvasively
N. Artzi1, C. Puron2, A. B. Ramos2, A. Groothuis3, G. Sahagian4, E. R. Edelman1;
1Massachusetts Inst. of Technology, Cambridge, MA, 2Univ.t Ramon Llull, Barcelona, SPAIN, 3Concorde BioMed. Sci. and Emerging Technologies, Lexington, MA, 4Tuftes Med. Sch., Boston, MA.
295
Multifunctional Rare-Earth Doped Nanoparticles in Encapsulated Albumin Nanocarriers for Tumor Targeting
D. J. Naczynski, T. Andelman, D. Pal, R. Riman, C. M. Roth, P. V. Moghe;
Rutgers Univ., Piscataway, NJ.
296
Lipopeptides Possessing Tripeptide, not Dipeptide, Head Groups Show Efficient DNA and siRNA Delivery
X-X. Zhang, M. W. Grinstaff;
Boston Univ., Boston, MA.
297
In-vivo and in-vitro detection of pancreatic cancer using functionalized CuInSe/ZnS QDs with NIR emission
K. Lee, H-E. C. Bhang, J. Park, J. Galloway, A. Maitra, M. Pomper, P. Searson;
Johns Hopkins Univ., Baltimore, MD.
298
Effect of Corona Lengths on Magnetic Resonance Imaging Sensitivity of Superparamagnetic Polymeric Micelles
C. Khemtong, O. Togao, J. Ren, C. W. Kessinger, M. Takahashi, A. D. Sherry, J. Gao;
Univ. of Texas Southwestern Med. Ctr. at Dallas, Dallas, TX.
299
Embeddable fiber-based biosensors for bacterial vaginosis
V. Reukov1, V. Maximov1, A. Vertegel1, R. Burtovyy1, I. Luzinov1, K. Kornev1, A. Moore2, R. Bevins2, P. Miller2;
1Clemson Univ., Clemson, SC, 2Greenville Hosp. System, Greenville, SC.
Biomaterials for Directed Stem Cell Differentiation
300
Combinatorial Effects of Matrix Elasticity and Cell Shape on Mesenchymal Stem Cell Differentiation
B. J. Gill, S. Nemir, J. L. West;
Rice Univ., Houston, TX.
301
Embryonic Stem Cell Differentiation is Modulated by Incorporation of Biomaterials within Embryoid Bodies
A. M. Bratt-Leal1, R. L. Carpenedo1, M. D. Ungrin2, P. W. Zandstra2, T. C. McDevitt1;
1Georgia Inst. of Technology, Atlanta, GA, 2Univ. of Toronto, Toronto, ON, CANADA.
302
A Bilayer Construct Controls Adipose Derived Stem Cell Differentiation
S. Natesan1, G. Zhang2, T. J. Walters1, R. J. Christy1, L. Suggs3;
1US Army Inst. of Surgical Res., Fort Sam Houston, TX, 2Univ. of Akron, Akron, OH, 3Univ. of Texas at Austin, Austin, TX.
303
Stem Cell Reactivity to Cardiovascular-Specific Differentiation Cues is Altered in Diabetic Conditions
H. S. Zhang, J. Maivelett, R. Stowers, M. E. Tedder, D. T. Simionescu, A. Simionescu;
Clemson Univ., Clemson, SC.
304
ECM Mimicking Hydrogel Scaffolds for Efficient Differentiation of Bone Marrow Stromal Cells into Various Zones of Articular Cartilage
L. H. Nguyen, A. K. Kudva, N. Saxena, K. Roy;
Univ. of Texas at Austin, Austin, TX.
305
Cyclodextrin-based Tuning of PEG Hydrogels for Improved Chondrogensis of Mesenchymal Stem Cells
A. Singh, Z. Ye, J. Coburn, L. Wo, J. Elisseeff;
Johns Hopkins Univ., Baltimore, MD.
306
Using Bioactive Gradients to Measure the Effect of Immobilized Peptide Density on Human Marrow Stromal Cell Proliferation and Differentiation
N. M. Moore1, N. J. Lin1, M. T. Cicerone1, M. L. Becker2;
1Natl. Inst. of Standards and Technology, Gaithersburg, MD, 2Univ. of Akron, Akron, OH.
307
Growth and Differentiation of Human Mesenchymal Stem Cells in Polymer-Peptide Hydrogels that Undergo Cell-Mediated Degradation
S. B. Anderson, M. J. Kissler, K. S. Anseth;
Univ. of Colorado, Boulder, CO.
Cancer Drug Delivery
308
Chimeric Polypeptide-Doxorubicin Conjugates Self-Assemble into Nanoparticles and Abolish Tumors after A Single Injection
M. CHEN1, J. A. MacKey2, J. R. .McDaniel1, T. Chu1, W. Liu1, A. J. Simnick1, A. Chilkoti1;
1Duke Univ., DURHAM, NC, 2Univ. OF Southern California, Los angeles, CA.
309
Theranostic Polymer Micelles for Targeted Imaging and Therapy of Lung Cancer
G. Huang;
UT Southwestern Med. Ctr., Dallas, TX.
310
Uptake of pro-apoptotic peptide amphiphiles by SJSA-1 cells in vitro induces specific cell death
D. Missirlis, M. Tirrell;
Univ. of California, Berkeley, Berkeley, CA.
311
Mechanistic Study of Biologic Intracellular Delivery with pH-Responsive Polymers
G. Y. Berguig, A. C. Convertine, C. L. Duvall, A. S. Hoffman, P. S. Stayton;
Univ. of Washington, Seattle, WA.
312
Prodrug Forming High Drug Loading Multifunctional Nanocapsules
Y. Shen1, E. Jin2, B. Zhang2, C. J. Murphy2, J. Tang1, M. Sui1, H. Tang2, M. Fan2, E. Van Kirk2, W. J. Murdoch2;
1Zhejiang Univ., Hangzhou, CHINA, 2Univ. of Wyoming, Laramie, WY.
313
Surface-Modified Monocytes Coupled to PAMAM Dendrimers for Targeted Anticancer Drug Delivery
C. A. Holden, Q. Yuan, W. Yeudall, D. Lebman, H. Yang;
Virginia Commonwealth Univ., Richmond, VA.
314
Characterization of in vivo drug release from in situ forming drug delivery implants
R. B. Patel1, L. Solorio1, H. Wu2, T. M. Krupka1, A. A. Exner1;
1Case Western Reserve Univ., Cleveland, OH, 2Case Western Reserve Univ. Med. Ctr., Cleveland, OH.
315
Nanospheric Chemotherapeutic and Chemoprotective Agents
L. Sheihet1, O. B. Garbuzenko2, T. Minko3, J. Kohn1;
1Rutgers Univ., New Jersey Ctr. for Biomaterials, Piscataway, NJ, 2Rutgers Univ., Ernest Mario Sch. of Pharmacy, Piscataway, NJ, 3Rutgers Univ., Ernest Mario Sch. of Pharmacy and NJ Ctr. for Biomaterials, Piscataway, NJ.
Cardiovascular Materials and Polyurethane Biomaterials (Symposia)
316
Cardiovascular Biomaterials and Polyurethanes: Issues and Perspectives
J. M. Anderson1, B. Jao1, E. Cosgriff-Hernandez2;
1Case Western Reserve Univ., Cleveland, OH, 2Texas A&M Univ., College Station, TX.
317
In Vivo Kinetic Degradation Analysis and Biocompatibility of Aliphatic Polyester Polyurethanes
P. T. Knight1, J. T. Kirk1, J. M. Anderson1, P. T. Mather2;
1Case Western Reserve Univ., Cleveland, OH, 2Syracuse Univ., Syracuse, NY.
318
Synthesis, processing and characterization of a biodegradable, elastomeric poly(ester-carbonate urethane) urea (PECUU) for soft tissue engineering
Y. Hong, J. Guan, K. Fujimoto, R. Hashizumi, A. L. Pelinescu, W. R. Wagner;
Univ. of Pittsburgh, Pittsburgh, PA.
319
Delivery of a collagen binding FGF-1 chimera from collagen hydrogels enhances smooth muscle cell proliferation
Y. Pang1, X. Wang2, A. A. Ucuzian3, E. M. Brey4, H. P. Greisler5;
1Illinois Inst. of Technology, Hines, IL, 2Xi’an Jiaotong Univ., Xi'an, CHINA, 3Loyola Univ. Med. Ctr., Maywood, IL, 4Illinois Inst. of Technology, Chicago, IL, 5loyola Uiniversity Med. Ctr., Maywood, IL.
320
Testing the in vivo compatibility and biodegradation of a degradable-polar/hydrophobic/ionic polyurethane for vascular tissue engineering applications
J. E. McBane1, K. Cai1, L. A. Matheson2, S. Sharifpoor1, R. S. Labow2, J. P. Santerre1;
1Univ. of Toronto, Toronto, ON, CANADA, 2Univ. of Ottawa Heart Inst., Ottawa, ON, CANADA.
321
Tunable and Injectable Hyaluronic Acid Hydrogels to Attenuate Post-Infarction Left Ventricular Remodeling
J. L. Ifkovits, E. Tous, M. Minakawa, M. Morita, J. H. Gorman, R. C. Gorman, J. A. Burdick;
Univ. of Pennsylvania, Philadelphia, PA.
322
Surface Modification with PEG and Hirudin for Protein Resistance and Thrombin Neutralization in Blood Contact
S. Alibeik, S. Zhu, J. Brash;
McMaster Univ., Hamilton, ON, CANADA.
Engineered Disease Models for Basic Research and Drug Discovery
323
Engineered Polystyrene Scaffolds For In Vitro Three-Dimensional Disease Models
M. K. Bergenstock1, W. Lau1, W. Sun2, Q. Liu1;
13D Biotek, North Brunswick, NJ, 2Drexel Univ., Philadelphia, PA.
324
Bisphosphonate Effects on Breast Cancer Colonization of Three-Dimensional Osteoblastic Tissue
G. N. Miller, V. Krishnan, A. M. Mastro, E. A. Vogler;
The Pennsylvania State Univ., University Park, PA.
325
Regulation of Cardiomyocyte Hypertrophy by Scaffold Stiffness, Ligand Presentation, and Co-culture
R. Boyer, K. Masters;
Univ. of Wisconsin-Madison, Madison, WI.
326
A novel 3D cell culture system could postpone primary hepatocytes dedifferentiation in vitro
M. Huihui, H. Yannan, H. Kanghong;
Inst. of Virology, Chinese Academy of Sci., 430071 Wuhan, PR China, Wuhan,Hubei, CHINA.
327
Harnessing Cellular Manipulation of the Cell-Matrix Interface to Control Stem Cell Fate
N. Huebsch, P. R. Arany, A. S. Mao, D. Shvartsman, O. A. Ali, J. Rivera-Feliciano, D. J. Mooney;
Harvard Univ., Cambridge, MA.
328
Anastellin irreversibly alters the mechanical properties of extracellular matrix fibronectin fibers
R. Andresen Eguiluz1, M. L. Smith2, E. Klotzsch3, V. Vogel3, D. Gourdon1;
1Cornell Univ., Ithaca, NY, 2Boston Univ., Boston, MA, 3Swiss Federal Inst. of Technology, Zurich, SWITZERLAND.
329
A microfluidic tumor model to study the effects of oxygen level and 3-D culture on tumor angiogenesis
S. S. Verbridge, N. Choi, Y. Zheng, D. J. Brooks, A. D. Stroock, C. Fischbach;
Cornell Univ., Ithaca, NY.
330
Engineered Tumor as an in Vitro Platform for the Assessment of Nanoparticle Drug Delivery System
L. A. Gurski1, X. Wang1, A. K. Jha1, M. C. Farach-Carson2, X. Jia1;
1Univ. of Delaware, Newark, DE, 2Rice Univ., Houston, TX.
