Posters

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Advances in Polymeric Nano-/Microparticle Formulation Techniques

402

Encapsulation of Cells by Microfluidics and Diffusive Michael-type Gelation of Synthetic Microgels

encapsulated cells; hydrogel; microspheres

D. M. Headen, Georgia Institute of Technology, Atlanta, GA

G. Aubry, Georgia Institute of Technology, Atlanta, Georgia

H. Lu, Georgia Institute of Technology, Atlanta, Georgia

A. Garcia, Georgia Institute of Technology, Atlanta, Georgia

403

Polyion Complex-Coated Polymeric Micelles with Highly Stability as Cell-Specific Drug Delivery Vehicles

block copolymer; drug delivery/release; nanomedicine

Y. Ohya, Kansai University, Suita, Osaka, Japan

Y. Morimoto, Kansai University, Suita, Japan

A. Takahashi, Kansai University, Suita, Japan

A. Kuzuya, Kansai University, Suita, Japan

A. Maruyama, Kyushu University, Fukuoka, Japan

Advances in Tissue Engineering Scaffolding

404

Core-Shell Hollow Microfibers by Triaxial Electrospinning

fiber; scaffolds; tissue engineering

A. Khalf, Oklahoma State University, Stillwater, OK

K. Singarapu, Oklahoma State Univeristy, Stillwater, Oklahoma

S. Madihally, Oklahoma State Univeristy, Stillwater, Oklahoma

405

Altering Fibrin Matrix Properties with pNIPAm Microgels for Wound Healing Applications

blood-material interaction; cell-material interactions; fibrin

A. M. Douglas, Georgia Institute of Technology, Atlanta, GA

406

Composites of Elastin-Like Polypeptide, Collagen, and Bioglass: Mechanical and Cell Culture Properties

bone; cell culture; tissue engineering

A. Janorkar, University of Mississippi Medical Center, Jackson, MS

T. Wheeler, University of Mississippi Medical Center, Jackson, Mississippi

N. Sbravati, University of Mississippi Medical Center, Jackson, Mississippi

407

Fabrication of Continuous PDMSstar-PEG Gradients for Osteochondral Regeneration

bioactive material; hydrogel; scaffolds

B. M. Bailey, Texas A&M University, College Station, TX

L. N. Nail, Texas A&M University, College Station, Texas

M. A. Grunlan, Texas A&M University, College Station, Texas

408

Novel (Poly)caprolactone (PCL) Scaffold Architecture for Tendon Tissue Engineering Applications

scaffolds; tendon prosthesis; tissue engineering

B. L. Banik, The Pennsylvania State University, State College, PA

J. L. Brown, The Pennsylvania State University, University Park, Pennsylvania

409

Dermal substitutes using electrospun silk fibroin nanofiber sponge

artificial skin; dermal substitutes

C. Park, Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Republic of Korea

410

Models to Predict the Resorption Rate of Bioresorbable Textile Scaffolds

absorbable; bioresorbable

C. R. Gajjar, North Carolina State University, Raleigh, NC

C. Li, North Carolina State University, Raleigh, North Carolina

S. Chung, Korea Institute of Science & Technology Evaluation & Planning, Seoul, Korea, Democratic People's Republic of

R. Payne, Tengion Inc., Winston-Salem, North Carolina

M. W. King, North Carolina State University, Raleigh, North Carolina

411

Tricomponent Fibrous Scaffolds with Dual Delivery of rhVEGF and rhBMP-2 for Bone Tissue Engineering

angiogenesis/neovascularization; controlled release; tissue engineering

C. Wang, The University of Hong Kong, Hong Kong SAR, Hong Kong

M. Wang, The University of Hong Kong, Hong Kong SAR, Hong Kong

412

Bone Marrow Absorption and Retention using Capillary Action via Micro-Channel Structure

bone marrow; cell adhesion; microstructure

D. S. Oh, Columbia University, New York, NY

F. Y. Lee, Columbia University, New York, New York

H. Tawfeek, Columbia University, New York, New York

P. H. Lim, Columbia University, New York, New York

D. Ganbat, Kyung Hee University, Yongin, Republic of Korea

Y. Kim, Kyung Hee University, Yongin, Republic of Korea

413

Bioactive Shape Memory Polymer Scaffolds for Bone Defect Repairs

bioactive material; scaffolds; smart materials

D. Zhang, Texas A&M University, College Station, TX

O. J. George, Texas A&M University, College Station, Texas

K. M. Petersen, Texas A&M University, College Station, Texas

M. A. Grunlan, Texas A&M University, College Station, Texas

414

Devitalized Cell Derived Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration

cartilage; extracellular matrix; tissue engineering

E. J. Levorson, Rice University, Houston, TX

O. Hu, Rice University, Houston, Texas

F. Kasper, Rice University, Houston, Texas

A. G. Mikos, Rice University, Houston, Texas

415

Self-assembling injectable peptide hydrogel for biomedical applications

cell culture; hydrogel; matrix

H. Huang, Kansas State University, Manhattan, KS

X. Sun, Kansas State University, Manhattan, Kansas

416

Isolation of Electrophysiological Biosignal Utilizing Silicone and Xenogeneic Extracellular Matrix

electrical stimulation; neural prosthesis; scaffolds

J. V. Larson, University of Michigan, Ann Arbor, MI

T. A. Kung, University of Michigan, Ann Arbor, Michigan

M. G. Urbanchek, University of Michigan, Ann Arbor, Michigan

P. S. Cederna, University of Michigan, Ann Arbor, Michigan

N. B. Langhals, University of Michigan, Ann Arbor, Michigan

417

Trilayered Design in Aortic Valve Tissue Engineering: A Polymeric Approach

heart valve; polyurethane(s); tissue engineering

J. Liao, Mississippi State University, Mississippi State, MS

J. Guan, Ohio State University, Columbus, Ohio

418

Differentiation of Mesenchymal Stem Cells on Polymeric Ligament Fascicle Substitute

biomimetic; cell differentiation; ligament(s)

K. L. Lee, Rensselaer Polytechnic Institute, Troy, NY

G. A. Ngai, Rensselaer Polytechnic Institute, Troy, New York

S. C. Varghese, Rensselaer Polytechnic Institute, Troy, New York

J. A. Cooper, Jr., Rensselaer Polytechnic Institute, Troy, New York

419

The effect of different sterilization techniques on material characteristics of a biodegradable nanocomposite polymer for use in tissue engineering purposes and its in-vitro and in-vivo biocompatibility

artificial skin; sterilization; surface characterization

L. Yildirimer, University College London, London, United Kingdom (Great Britain)

420

Shape-memory Activated Change in Scaffold Fiber Alignment Directs Stem Cell Morphology

scaffolds; smart materials; stem/progenitor cells

L. Tseng, Syracuse University, Syracuse Biomaterials Institute, Syracuse, NY

421

In Vitro Osteoblastic Differentiation on Bioactive Glass and Glass-ceramic Surfaces

bioactive glass; cell culture; cell differentiation

O. C. Alves, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto (SP), Brazil, Ribeirão Preto-SP, Brazil

F. S. Oliveira, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto (SP), Brazil, Ribeirão Preto, Brazil

E. D. Zanotto, Federal University of Sao Carlos, Sao Carlos (SP), Brazil, São Carlos, Brazil

O. Peitl, II, Federal University of Sao Carlos, Sao Carlos (SP), Brazil, São Carlos, Brazil

M. M. Beloti, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto (SP), Brazil, Ribeirão Preto, Brazil

A. L. Rosa, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto (SP), Brazil, Ribeirão Preto, Brazil

P. T. Oliveira, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto (SP), Brazil, Ribeirão Preto, Brazil

422

Modular Biomaterial Systems for Rapid and Functional Vascularization

angiogenesis/neovascularization; endothelial cells; scaffolds

R. T. Annamalai, Wayne State University, Detroit, MI

D. R. Armant, Wayne State University, Detroit, Michigan

H. W. T. Matthew, Wayne State University, Detroit, Michigan

423

Decellularized Liver Tissue Based Hydrogel for Repair and Regeneration

biomimetic; extracellular matrix; tissue engineering

R. E. Coronado, University of Texas Health Science Center San Antonio / University of Texas at San Antonio, San Antonio, TX

424

Poly(ε-caprolactone) Shape Memory Polymer for Filling Critical-Sized Defects

bone; scaffolds; smart materials

R. M. Baker, Syracuse University, Syracuse, NY

J. H. Henderson, Syracuse University, Syracuse, New York

P. T. Mather, Syracuse University, Syracuse, New York

425

The Development of Synthetic Polypeptide-Based Hydrogel Systems for Biomaterials

scaffolds

S. M. Morey, Massachusetts Institute of Technology, Medford, MA

A. M. Oelker, Massachusetts Institute of Technology, Cambridge, Massachusetts

L. G. Griffith, Massachusetts Institute of Technology, Cambridge, Massachusetts

P. T. Hammond, Massachusetts Institute of Technology, Cambridge, Massachusetts

426

Hyaluronan-Based Multi-Phasic Scaffolds for Osteochondral Tissue Regeneration

hydrogel; regenerative medicine; scaffolds

S. L. Fenn, University of Vermont, Burlington, VT

T. Miao, University of Vermont, Burlington, Vermont

R. A. Oldinski, University of Vermont, Burlington, Vermont

427

Comparison of Elastomeric Polymers for Bladder Regeneration

biocompatibility/soft tissue; tissue engineering; urology/urological engineeing

S. Sivaraman, Clemson university, Clemson, SC

N. Amoroso, University of Pittsburgh, Pittsburgh, Pennsylvania

W. Wagner, University of pittsburgh, Pittsburgh, Pennsylvania

S. Sant, University of Pittsburgh, Pittsburgh, Pennsylvania

J. Nagatomi, Clemson University, Clemson, South Carolina

428

Development and Characterization of a Novel Polycaprolactone Fumarate (PCLF) Scaffold Manufactured through a Sacrificial Molding Technique

mechanical properties; scaffolds; tissue engineering

S. C. Chase, Mayo Clinic, Rochester, MN

E. Wagner, Mayo Clinic, Rochester, Minnesota

D. Bravo, Mayo Clinic, Rochester, Minnesota

M. Dadsetan, Mayo Clinic, Rochester, Minnesota

S. Kakar, Mayo Clinic, Rochester, Minnesota

M. Yaszemski, Mayo Clinic, Rochester, Minnesota

429

Spatial control of drug delivery in multilayered poly(vinyl alcohol) scaffold for tissue regeneration

controlled release; scaffolds; tissue engineering

T. Miao, University of Vermont, Burlington, VT

T. Miao, University of Vermont, Burlington, Vermont

R. A. Oldinski, University of Vermont, Burlington, Vermont

430

Novel Scaffold Design that Adds a Third Dimension to Engineering Complex Tissues

scaffolds; tissue engineering

T. He, North Carolina State University, Raleigh, NC

K. Sippel, ITA, RWTH Aachen University, Raleigh, North Carolina

A. O. Inman, III, North Carolina State University, Raleigh, North Carolina

N. Monteiro-Riviere, North Carolina State University, Raleigh, North Carolina

S. Lee, Wake Forest Institute of Regenerative Medicine, Winston-Salem, North Carolina

M. W. King, College of Textiles, North Carolina University & College of Textiles, Donghua University, Raleigh, North Carolina

431

Is Interconnected Pore Volume Equal to Pore Size? Novel Technique to Evaluate Internal Pore Volume of Tissue Engineering Scaffolds

porosity; test method; tissue engineering

T. He, North Carolina State University, Raleigh, NC

J. Liang, North Carolina State University, Raleigh, North Carolina

S. H. Bernacki, North Carolina State University, Raleigh, North Carolina

M. W. King, North Carolina State University, Raleigh, North Carolina

432

Inverse Opal Scaffolds for Regenerative Medicine: Fabrication, Advantages and Applications

porosity; scaffolds; tissue engineering

Y. Zhang, Georgia Institute of Technology, Atlanta, GA

K. P. Regan, Bates College, Lewiston, Maine

Y. Xia, Georgia Institute of Technology, Atlanta, Georgia

900

Grooved PLGA Films Incorporated with RGD/YIGSR Peptides for Potential Application on Skeletal Muscle Tissue Engineering

cell differentiation; cell-material interactions; tissue engineering

P. WANG, Swinburne University of Technology, Melbourne, Australia

901

Self-assembling “smart” hydrogels with bioadhesive properties for tissue engineering applications

biocompatibility/soft tissue; cytotoxicity; graft/copolymer

J. Vernengo, Rowan University, Glassboro, NJ

C. Wiltsey, Rowan University, Glassboro, New Jersey

T. Christiani, Rowan University, Glassboro, New Jersey

J. Williams, Rowan University, Glassboro, New Jersey

J. Scaramazza, Rowan University, Glassboro, New Jersey

C. Van Sciver, Rowan University, Glassboro, New Jersey

K. Toomer, Rowan University, Glassboro, New Jersey

J. Sheehan, Rowan University, Glassboro, New Jersey

A. Branda, Rowan University, Glassboro, New Jersey

J. Kadlowec, Rowan University, Glassboro, New Jersey

C. Iftode, Rowan University, Glassboro, New Jersey

902

Novel Biointegrative Cross-linked Degradable Polyurethane Scaffold Matrix

absorbable; articular cartilage; tissue engineering

A. Datta, Biomerix Corporation, Somerset, NJ

D. Grande, Feinstein Institute for Medical Research, Manhasset, New York

903

Construction of a Collagen-Based, Split Thickness Cornea Substitute

tissue engineering

V. N. HASIRCI, METU, Ankara, Turkey

A. ACUN, METU, Ankara, Turkey

904

A three-dimensional co-culture model of the aortic valve using magnetic levitation

cell-cell interactions; extracellular matrix; heart valve

L. R. Balaoing, Rice University, Houston, TX

H. Tseng, Rice University, Houston, Texas

B. Grigoryan, Texas A&M University, College Station, Texas

R. M. Raphael, Rice University, Houston, Texas

T. C. Killian, Rice University, Houston, Texas

G. R. Souza, Nano3D Biosciences, Houston, Texas

K. J. Grande-Allen, Rice University, Houston, Texas

905

Synthesis of a Novel Injectable, ROS-degradable Tissue Engineering Scaffold

biodegradation

J. R. Martin, Vanderbilt University, Nashville, TN

Animal Models for Biomaterial and Medical Device Testing

433

Injectable Poly(N-isopropylacrylamide)-grafted HA and Chitosan Hydrogel as a Barrier for Prevention of Postoperative Abdominal Adhesion in Laparoscopic Surgery

biodegradation; hydrogel; tissue adhesion

C. Chen, Chang Gung University, Taoyuan, Taiwan, ROC, Tao-Yuan, Taiwan

434

Development of Pre-Clinical In Vivo Models to Assess the Efficacy of Antimicrobial Products to Reduce Device-Related Infections

animal model; antimicrobial

L. K. Hansen, WuXi AppTec, Inc., St. Paul, MN

D. Johnson, WuXi AppTec, Inc., St. Paul, Minnesota

K. Jenkins, WuXi AppTec, Inc., St. Paul, Minnesota

C. Bauer, WuXi AppTec, Inc., St. Paul, Minnesota

435

Platelet activation in juvenile ovines implanted with the PediaFlow® 4th generation pediatric ventricular assist device

heart assist device; hemocompatibility; platelet

V. Shankarraman, University of Pittsburgh, Pittsburgh, PA

S. Olia, University of Pittsburgh, Pittsburgh, Pennsylvania

E. Kocyildirim, University of Pittsburgh, Pittsburgh, Pennsylvania

T. M. Maul, University of Pittsburgh, Pittsburgh, Pennsylvania

M. V. Kameneva, University of Pittsburgh, Pittsburgh, Pennsylvania

S. Snyder, LaunchPoint Technologies, Goleta, California

P. D. Wearden, University of Pittsburgh, Pittsburgh, Pennsylvania

H. S. Borovetz, University of Pittsburgh, Pittsburgh, Pennsylvania

W. R. Wagner, University of Pittsburgh, Pittsburgh, Pennsylvania

906

Evaluation of Magnesium Alloys for Use as Degradable Stents in a Rat Trachea Bypass Model

animal model; biodegradation; metal (alloys)

T. Gilbert, ACell, Columbia, MD

907

Anatomical Effects in the Development of a Delayed Wound Healing Model

animal model

K. A. Kentner, ACell, Inc., Columbia, MD

K. Stuart, ACell, Inc., Columbia, Maryland

K. Lam, Bridge PTS, San Antonia, Texas

C. Koeller, Bridge PTS, San Antonia, Texas

D. Ochoa, Bridge PTS, San Antonia, Texas

R. Patton, Bridge PTS, San Antonio, Texas

T. Laufenberg, Bridge PTS, San Antonio, Texas

C. Lewis, Bridge PTS, San Antonio, Texas

P. Attar, Bridge PTS, San Antonio, Texas

A. D. Janis, ACell, Inc., Columbia, Maryland

Benchtop Tissue Surrogates to Model Drug Uptake and Efficacy

436

The Development of Hydrogel Microwells for Perfused 3D Culture of Hepatocytes

hydrogel; scaffolds

J. Shepard, Massachusetts Institute of Technology, Cambridge, MA

V. Chan, University of Illinois at Urbana-Champaign, Urbana, Illinois

M. Rhoads, Massachusetts Institute of Technology, Cambridge, Massachusetts

M. Raredon, Massachusetts Institute of Technology, Cambridge, Massachusetts

R. Dyer, Massachusetts Institute of Technology, Cambridge, Massachusetts

P. Hammond, Massachusetts Institute of Technology, Cambridge, Massachusetts

R. Bashir, University of Illinois at Urbana-Champaign, Urbana, Illinois

L. Griffith, Massachusetts Institute of Technology, Cambridge, Massachusetts

Biofunctional Polymers for Gene Delivery

437

Hemocompatible pH-responsive polymeric nanoparticle for intravenous siRNA

hemocompatibility; nanomedicine; smart materials

C. E. Nelson, Vanderbilt University, Nashville, TN

J. R. Kintzing, Vanderbilt University, Nashville, Tennessee

J. M. Shannon, Vanderbilt Univeristy, Nashville, Tennessee

M. K. Gupta, Vanderbilt University, Nashville, Tennessee

C. L. Duvall, Vanderbilt Univeristy, Nashville, Tennessee

438

Lyophilized Poly(ethylene glycol-b-(dimethylaminoethyl methacrylate-co-butyl methacrylate))-DNA Nanoparticles for Nonviral Gene Therapy

gene therapy/gene delivery; nanomaterials/nanophase; smart materials

E. J. Adolph, Vanderbilt University, Nashville, TN

C. E. Nelson, Vanderbilt University, Nashville, Tennessee

J. M. Shannon, Vanderbilt University, Nashville, Tennessee

C. L. Duvall, Vanderbilt University, Nashville, Tennessee

S. A. Guelcher, Vanderbilt University, Nashville, Tennessee

439

Transformation of Cationic Materials into Neutral Biocompatible Systems for siRNA Delivery: Property and Function Characterization

controlled release; gene therapy/gene delivery; polymer

J. Liu, Georgia Institute of Technology, Atlanta, GA

J. Zhou, Peking University, Beijing, China

Y. Luo, Peking University, Beijing, China

440

Spider Silk Gene Delivery Systems for Intracellular Cell Targeting

biomolecular engineering; gene therapy/gene delivery; smart materials

O. Tokareva, Tufts University, Medford, MA

D. Glettig, Tufts University, Medford, Massachusetts

R. Abbott, Tufts University, Medford, Massachusetts

D. L. Kaplan, Tufts University, Medford, Massachusetts

443

Comb-shaped Cationic Polycarbonates for Gene Delivery and Antimicrobial Applications

antimicrobial; gene therapy/gene delivery; graft/copolymer

Z. Ong, Institute of Bioengineering and Nanotechnology, Singapore, Singapore

D. J. Coady, IBM Almaden Research Centre, San Jose, California

J. L. Hedrick, IBM Almaden Research Centre, San Jose, California

Y. Yang, Institute of Bioengineering and Nanotechnology, Singapore, Singapore

870

Animal Model of Open Femur-Fracture Infection Using Noninvasive In Vivo Bioluminescence Imaging

animal model; bacterial adherence; infection

B. Li, West Virginia University School of Medicine, Morgantown, WV

P. Farjo, West Virginia University, Morgantown, West Virginia

T. Hamza, West Virginia University, Morgantown, West Virginia

871

Tissue Response to Hydrogel Scaffolds Delivering Bone Morphogenetic Protein-2 for Bone Augmentation

bone; controlled release; hydrogel

L. A. Kinard, Rice University, Houston, TX

R. L. Dahlin, Rice University, Houston, Texas

A. M. Henslee, Rice University, Houston, Texas

P. P. Spicer, Rice University, Houston, Texas

C. Chu, Rice University, Houston, Texas

F. K. Kasper, Rice University, Houston, Texas

A. G. Mikos, Rice University, Houston, Texas

Bioinspired Smart Materials for Regenerative Medicine Applications

444

Hyaluronic Acid-Catechol Hydrogel for Liver Tissue Engineering

encapsulated cells; hydrogel; tissue engineering

J. Lee, Yonsei University, Seoul, Republic of Korea

J. Shin, Yonsei University, Seoul, Republic of Korea

C. Lee, Yonsei University, Seoul, Republic of Korea

S. Cho, Yonsei University, Seou, Republic of Korea

445

Theoretical Piezoelectric Composite Model for Use in a Spinal Fusion Cage

smart materials; spinal implant

L. Friis, University of Kansas, Lawrence, KS

N. E. Tobaben, University of Kansas, Lawrence, Kansas

J. P. Domann, University of Kansas, Lawrence, Kansas

446

Enzymatic Stability of Novel Biomimetic Aggrecan for Treatment of Tissue Degeneration

biomimetic; enzyme(s)

S. Lightfoot Vidal, Drexel University, Philadelphia, PA

447

Enzymatic surface erosion of high-moduli polycarbonates based on natural phenols

biodegradation; mechanical properties; polymer

S. D. Sommerfeld, Rutgers - The State University of New Jersey, Piscataway, NJ

Z. Zhang, Rutgers - The State University of New Jersey, Piscataway, New Jersey

M. Costache, Rutgers - The State University of New Jersey, Piscataway, New Jersey

J. Kohn, Rutgers - The State University of New Jersey, Piscataway, New Jersey

448

Growth Factor Delivery Systems that Mimic Natural Extracellular Matrix and Supply Biological Molecules in Bone Tissue Engineering

bioactive material; nanotechnology

W. Swieszkowski, Sr., Warsaw University of Technology, Warsaw, Poland

Biological Responses to Surface Modification of Biomaterials

449

SLIPS Surface Treatment of Medical Devices that Prevents Blood Clot Formation in the Absence of Anticoagulants

hemocompatibility; surface modification; thrombogenicity

D. C. Leslie, Harvard University, Boston, MA

A. Waterhouse, Harvard University, Boston, Massachusetts

A. L. Watters, Harvard University, Boston, Massachusetts

J. B. Berthet, Harvard University, Boston, Massachusetts

T. M. Valentin, Harvard University, Boston, Massachusetts

A. Hansen, Children's Hospital Boston, Boston, Massachusetts

A. Nedder, Children's Hospital Boston, Boston, Massachusetts

T. Wong, Harvard University, Cambridge, Massachusetts

P. Kim, Harvard University, Cambridge, Massachusetts

M. Super, Harvard University, Boston, Massachusetts

J. Aizenberg, Harvard University, Cambridge, Massachusetts

D. E. Ingber, Harvard University, Boston, Massachusetts

450

Mechanically-Stimulated Co-cultured Tissue-Specific Scaffolds for Tendon/Bone Interface Engineering

extracellular matrix; tendon prosthesis; tissue engineering

J. O. Cooper, The University of Memphis, Memphis, TN

M. Goodhart, The University of Memphis, Memphis, Tennessee

J. D. Bumgardner, The University of Memphis, Memphis, Tennessee

W. O. Haggard, The University of Memphis, Memphis, Tennessee

J. A. Jennings, The University of Memphis, Memphis, Tennessee

451

In vivo Evaluation of an Endothelial Cell-Specific Biomimetic Peptide Fluorosurfactant Polymer Coating for Expanded Poly(tetrafluoroethylene) Vascular Grafts

in vivo; surface modification; vascular graft

J. Bastijanic, Case Western Reserve University, Cleveland, OH

L. Dudash, Case Western Reserve University, Cleveland, Ohio

F. Kligman, Cleveland Clinic Foundation, Cleveland, Ohio

M. T. Allemang, University Hospitals, Cleveland, Ohio

R. O. Lakin, University Hospitals, Cleveland, Ohio

B. A. Eslahpazir, University Hospitals, Cleveland, Ohio

V. S. Kashyap, University Hospitals, Cleveland, Ohio

K. Kottke-Marchant, Cleveland Clinic Foundation, Cleveland, Ohio

R. Marchant, Case Western Reserve University, Cleveland, Ohio

452

Innovative Injury versus Non-Injury Migration Assays

cell-cell interactions; extracellular matrix; wound healing

K. R. Ammann, University of Arizona, Tucson, AZ

K. J. DeCook, University of Arizona, Tucson, Arizona

P. L. Tran, University of Arizona, Tucson, Arizona

M. J. Slepian, University of Arizona, Tucson, Arizona

453

In Vitro Behavior of Human Osteoblastic Cells Cultured on Titanium Surfaces Modified by Oxidative Nanopatterning

cell-material interactions; nanomodified surfaces; titanium (alloys)

K. F. B. Prado, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

F. Variola, University of Ottawa, Ottawa, Canada

M. R. W. Ferreira, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

R. R. Fernandes, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

F. G. Azevedo, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

454

Improved Osteoblast Response to UV-Irradiated Superhydrophilic PMMA/TiO2 Nanocomposites

bone cement (= PMMA, acrylic); cell adhesion; hydrophilic

M. Shayan, University of Pittsburgh, Pittsburgh, PA

455

Macrophage Interactions with Nanoporous Titanium Surfaces

cell-material interactions; nanomodified surfaces; titanium (alloys)

M. B. Ariganello, Université de Montréal, Ottawa, ON, Canada

456

Surface Chemistry Modulation of Valvular Interstitial Cells

cell-material interactions; heart valve; tissue engineering

M. N. Rush, University of New Mexico, Albuquerque, NM

E. Esquivel, University of New Mexico, Albuquerque, New Mexico

E. L. Hedberg-Dirk, University of New Mexico, Albuquerque, New Mexico

457

Anti-fouling Medical Coatings Prepared with Amphiphilic PEG-Silanes

silicone(s) PDMS

M. A. Grunlan, Texas A&M University, College Station, TX

M. L. Hawkins, Texas A&M University, College Station, Texas

M. A. Rufin, Texas A&M University, College Station, Texas

J. A. Gruetzner, Texas A&M University, College Station, Texas

458

The use of a library of industrial materials to determine the nature of substrate-dependent performance of primary adherent human cells

cell-material interactions; endothelial cells; epithelial cells

M. Ni, Institute of Bioengineering and Nanotechnology, Singapore, Singapore

459

Decreasing bacterial colonization around the Intraosseous Transcutaneous Amputation Prosthesis without inducing cytotoxicity to fibroblasts using hydroxyapatite, silver and fibronectin

antimicrobial

M. Chimutengwende-Gordon, Institute of Orthopaedics and Musculoskeletal Science, University College London, London, United Kingdom (Great Britain)

C. Pendegrass, Institute of Orthopaedics and Musculoskeletal Science, UCL, Stanmore, United Kingdom (Great Britain)

G. Blunn, Institute of Orthopaedics and Musculoskeletal Science, Stanmore, United Kingdom (Great Britain)

460

Octacalcium phosphate/gelatin composite: the effect of synthesis and crystal elongation on rabbit tibia bone repair

bone ingrowth; calcium phosphate(s); ceramic

O. Suzuki, Tohoku University Graduate School of Dentistry, Sendai, Japan

461

Osteopontin Expression by Osteogenic Cells Cultured on Nanoporous Tiatanium

cell-material interactions; nanomodified surfaces; titanium (alloys)

P. Adachi, Jr., University of Sao Paulo, Ribeirao Preto, Brazil

W. M. A. Maximiano, Jr., School of Dentistry of Ribeirao Preto, Ribeirao Preto, Brazil

A. L. Rosa, School of Dentistry of Ribeirao Preto, Ribeirao Preto, Brazil

A. Nanci, Université de Montréal, Montréal, Québec, Canada

P. T. Oliveira, School of Dentistry of Ribeirao Preto, Ribeirao Preto, Brazil

462

Amino Acid - Based Antifouling Poly (serine methacrylate)

polymer; protein adsorption; surface modification

Q. Liu, University of Akron, Akron, OH

A. Singh, University of Akron, Akron, Ohio

L. Liu, University of Akron, Akron, Ohio

463

Effect of protein adsorption on human osteoblast response to porous ferritic fibre networks

fibrin; in vitro; protein adsorption

R. L. Spear, University of Cambridge, Cambridge, United Kingdom (Great Britain)

B. Srigengan, University of Cambridge, Cambridge, United Kingdom (Great Britain)

A. E. Markaki, University of Cambridge, Cambridge, United Kingdom (Great Britain)

464

Interaction of Endothelial and Smooth Muscle Cells with Paclitaxel-Immobilized Self Assembled Monolayers

cell adhesion; endothelialization; stents

S. Lamichhane, The University of South Dakota, Sioux Falls, SD

S. Lancaster, South Dakota Innovation Partners, Sioux Falls, South Dakota

E. Thiruppathi, The University of South Dakota, Sioux Falls, South Dakota

G. Mani, The University of South Dakota, Sioux Falls, South Dakota

908

Limits to the utilization of polydopamine coating with the example of flax fibers as a substrate

cell adhesion; coating(s); fiber

S. A. A. Michel, Maastricht University, Maastricht, Netherlands

M. L. W. Knetsch, Maastricht University, Maastricht, Netherlands

L. H. Koole, Maastricht University, Maastricht, Netherlands

909

Combined Treatment of a Tendon Gap with a Biomimetic Electrospun Scaffold, Stromal Cells and GDF5

graft/copolymer; growth factor; tendon prosthesis

R. James, University of Connecticut Health Center, Farmington, CT

Biologically Derived Materials From Natural Resources

465

Basic Properties of Starfish Bone and Its Phase Transformation Reaction in Phosphate Salt Solution

calcium phosphate(s)

A. Takeuchi, Shinshu University, Matsumoto, Japan

D. Honda, Shinshu University, Matsumoto, Japan

K. Ishikawa, Kyushu University, Fukuoka, Japan

466

Material Screening for Skeletal Muscle Regeneration

hydrogel; muscle; tissue engineering

B. E. Pollot, University of Texas at San Antonio, San Antonio, TX

C. R. Rathbone, United States Army Institute of Surgical Research, Fort Sam Houston, Texas

J. C. Wenke, US Army Institute of Surgical Research, Fort Sam Houston, Texas

T. Guda, University of Texas at San Antonio, San Antonio, Texas

467

Comparison of Mechanical Response of Intact Artery and Isolated Arterial Elastin

biomechanics; mechanical properties; vascular

B. Stephen, University of Maryland Baltimore County, Baltimore, MD

L. Topoleski, University of Maryland Baltimore County, Baltimore, Maryland

468

Guest-Host Assembly of Shear-Thinning Hyaluronic Acid Hydrogels

catheter; hydrogel; sustained release

C. B. Rodell, University of Pennsylvania, Philadelphia, PA

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

469

Magnetically guided alignment of bio-nanofibers into ordered structures for controlling stem cell behaviors

biomimetic; nanoassembled devices; nanotechnology

C. Mao, University of Oklahoma, Norman, OK

470

Design and Synthesis of an Adherent Artificial Pulmonary Pleura

artificial lung; hydrogel; implant interface

D. E. Wagner, University of Vermont, Burlington, VT

R. A. Oldinski, University of Vermont, Burlington, Vermont

N. R. Bonenfant, University of Vermont, Burlington, Vermont

D. J. Weiss, University of Vermont, Burlington, Vermont

471

Promoting Chondrogenesis and Maintaining the Bioactivity of Proteins using a Biomimetic Material

biomimetic; growth factor; tissue engineering

G. Portocarrero, New Jersey Institute of Technology, Hillside, NJ

A. Molina, New Jersey Institute of Technology, Newark, New Jersey

G. Collins, New Jersey Institute of Technology, Newark, New Jersey

T. Arinzeh, New Jersey Institute of Technology, Newark, New Jersey

472

Thermally stable polylactide stereocomplex conjugated by bio-based compound at both initiating and terminal groups

biocompatibility/soft tissue; polymer

H. Ajiro, Osaka University, Suita, Japan

T. H. Thi, Viet Tri University of Industry, Phu Tho, Viet Nam

T. Fujiwara, The University of Memphis, Memphis, Tennessee

M. Akashi, Osaka University, Suita, Japan

473

Biomimetic apatite-coated chitosan based scaffolds for bone regeneration

cell-material interactions; drug delivery/release; scaffolds

H. Park, University of California, Los Angeles, Los Angeles, CA

474

Three-Dimensional Biomolecular Architectures for Characterizing Bacterial Sociomicrobiology

encapsulated cells

J. B. Shear, University of Texas at Austin, Austin, TX

J. Connell, University of Texas at Austin, Austin, Texas

M. Fitzpatrick, University of Texas at Austin, Austin, Texas

E. T. Ritschdorff, University of Texas at Austin, Austin, Texas

E. C. Spivey, University of Texas at Austin, Austin, Texas

M. Whiteley, University of Texas at Austin, Austin, Texas

475

DMSO Resistance of Hyaluronic Acid-Based Hydrophilic Coatings

coating(s); hydrophilic

J. Rosenman, Biocoat, Inc., Horsham, PA

E. Pervin, Biocoat, Inc., Horsham, Pennsylvania

J. Simon, Biocoat, Inc., Horsham, Pennsylvania

476

Chitosan Source Evaluation by Two Degradation Assessment Methods for a Local Delivery Device

biodegradation; polymer

K. Smith, The University of Memphis, Memphis, TN

A. Parker, The University of Memphis, Memphis, Tennessee

A. Jennings, The University of Memphis, Memphis, Tennessee

W. Haggard, The University of Memphis, Memphis, Tennessee

477

Naturally Derived Fatty Acid Biomaterials for Local Drug Delivery

absorbable; drug delivery/release

K. M. Faucher, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, NH

N. Artzi, MIT, Cambridge, Massachusetts

T. Albergo, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, New Hampshire

J. Bienkiewicz, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, New Hampshire

S. Conroy, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, New Hampshire

A. Dale, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, New Hampshire

I. Kozlova, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, New Hampshire

E. R. Edelman, MIT, Cambridge, Massachusetts

P. Martakos, Atrium Medical Corporation, MAQUET GETINGE Group, Hudson, New Hampshire

478

Fabrication of a Bioinspired Cellulose-based Composite with Biocompatible Surface as a Potential Scaffold in Vascular Tissue Engineering

biocompatibility/soft tissue; biomimetic; nanomaterials/nanophase

P. Pooyan, Georgia Institute of Technology, Atlanta, GA

L. P. Brewster, 1) Emory University School of Medicine; 2) Georgia Institute of Technology, Atlanta, Georgia

R. Tannenbaum, 1) University of Alabama at Birmingham; 2) Georgia Institute of Technology, Atlanta, Georgia

H. Garmestani, Georgia Institute of Technology, Atlanta, Georgia

479

Fabrication of Silk/Chitosan-based Hydrogels by Gamma Irradiation

biocompatibility/soft tissue; hydrogel; radiation

P. Uttayarat, Thailand Institute of Nuclear Technology (Public Organization), Nakornnayok, Thailand

480

Crosslinked Hyaluronic Acid Hydrogel Networks Designed as Mechano-stimulators

hydrogel; polymer

P. S. Varde, Syracuse University, Syracuse, NY

J. M. Hasenwinkel, Syracuse University, Syracuse, New York

481

Peptide block copolymers to improve silk biomaterial/hard-tissue interfaces

block copolymer; composite/hard tissue; hydroxy apatite

R. Calabrese, Tufts University, Medford, MA

G. Qin, Tufts University, Medford, Massachusetts

D. L. Kaplan, Tufts University, Medford, Massachusetts

482

Two-layer silk tubular scaffolds for small diameter blood vessel regeneration

scaffolds; tissue engineering; vascular graft

V. Catto, Politecnico di Milano, Milano, Italy

R. Elia, Tufts University, Medford, Massachusetts

M. Tanzi, Politecnico di Milano, Milano, Italy

G. Freddi, INNOVHUB - Stazioni Sperimentali per l'Industria - Divisione Stazione Sperimentale per la Seta, Milano, Italy

S. Farè, Politecnico di Milano, Milano, Italy

D. L. Kaplan, Tufts University, Medford, Massachusetts

483

A Comparative Study of Decellularized Extracellular Matrix Biomaterials from Different Sources

bioactive material

x. luo, Tongji Hospital, Huazhong University of Science and Technology,Wuhan, People's Republic of China, Wuhan,Hubei, China

484

Self-Deployable Current Source Fabricated From Edible Materials

electrical stimulation; nanoassembled devices; smart materials

Y. Kim, Carnegie Mellon University, Pittsburgh, PA

C. J. Bettinger, Carnegie Mellon University, Pittsburgh, Pennsylvania

S. Chun, Carnegie Mellon University, Pittsburgh, Pennsylvania

J. Whitacre, Carnegie Mellon University, Pittsburgh, Pennsylvania

910

Investigating the osteogenic potential of decellularized extracellular matrices derived from different tissues of origin

osteogenesis

V. Z. Beachley, Johns Hopkins University, Baltimore, MD

M. Gibson, Johns Hopkins University, Baltimore, Maryland

J. Elisseeff, Johns Hopkins University, Baltimore, Maryland

911

Solution Structure of Poly-amido-saccharides

biomimetic; molecular modeling; polymer

S. E. Stidham, Boston University, Boston, MA

S. L. Chin, Boston University, Boston, Massachusetts

E. L. Dane, Boston University, Boston, Massachusetts

M. W. Grinstaff, Boston University, Boston, Massachusetts

Biologically Inspired Biomaterials Approaches for Cancer Research

485

Biphasic Cell Responses on Laterally Mobile Films

biomimetic; block copolymer; cell-material interactions

A. P. Kourouklis, Umass, Amherst, Amherst, MA

R. V. Lerum, Umass, Amherst, Amherst, Massachusetts

H. Bermudez, Umass, Amherst, Amherst, Massachusetts

486

Synergy of matrix stiffness and EGFR inhibition in apoptosis of pancreatic tumor cells in 3D

cell-material interactions; hydrogel; tumor

C. Lin, Indiana University-Purdue University at Indianapolis, Indianapolis, IN

C. Ki, Indiana University-Purdue University at Indianapolis, Indianapolis, Indiana

487

Stem cells as a photosensitizer carrier to attack cancer cells for photodynamic therapy of breast cancer

drug delivery/release; nanotechnology

C. Mao, University of Oklahoma, Norman, OK

488

Matrix Rigidity Regulates Osteolytic Gene Expression in Oral Squamous Cell Carcinomas

polyurethane(s); rigidity; tumor

J. M. Page, Vanderbilt University, Nashville, TN

489

Hyaluronic Acid Based Hydrogels with Tunable Properties for the Study of Breast Cancer

carcinogenesis; extracellular matrix

S. A. Fisher, University of Toronto, Toronto, ON, Canada

S. C. Owen, University of Toronto, Toronto, Ontario, Canada

M. S. Shoichet, University of Toronto, Toronto, Ontario, Canada

912

Fibronectin and Type I Collagen Synergy in Tumor Progression

fibronectin/vitronectin; matrix; tumor

K. Wang, Cornell University, Ithaca, NY

R. Andresen-Eguiluz, Cornell University, Ithaca, New York

B. Seo, Cornell University, Ithaca, New York

S. Hu, Cornell University, Ithaca, New York

C. Fischbach, Cornell University, Ithaca, New York

D. Gourdon, Cornell University, Ithaca, New York

Biomaterial Strategies for Innervation, Nerve Repair and Integration

490

Multifunctional Alginate Scaffolds for Spinal Cord Repair

drug delivery/release; hydrogel; nerve regeneration

D. Shahriari, Michigan State University, East Lansing, MI

D. Lynam, Michigan State University, East Lansing, Michigan

K. Koffler, University of California, San Diego, La Jolla, California

C. Chan, Michigan State University, East Lansing, Michigan

M. Tuszynski, University of California, San Diego, La Jolla, California

J. Sakamoto, Michigan State University, East Lansing, Michigan

491

Potential Neural Interface Material Printed via Projection Micro-StereoLithography (PmSL)

biocompatibility/soft tissue; interface(s); neural prosthesis

K. N. Cicotte, University of New Mexico Sandia National Laboratories, Albuquerque, NM

S. Buerger, Sandia National Laboratories, Albuquerque, New Mexico

P. P. Lin, MD Anderson Cancer Center, Houston, Texas

G. Reece, MD Anderson Cancer Center, Houston, Texas

E. L. Hedberg-Dirk, University of New Mexico, Albuquerque, New Mexico

S. M. Dirk, Sandia National Laboratories, Albuquerque, New Mexico

492

Intracortical Electrodes of Different Material, Shape, Size and Tethering Induce Differential Inflammatory Responses that Significantly Impact Chronic Electrode Function.

biocompatibility/soft tissue; cytokines; neural prosthesis

L. Karumbaiah, Georgia Institute of Technology, Atlanta, GA

T. Saxena, Georgia Institute of Technology, Atlanta, Georgia

K. Patil, Georgia Institute of Technology, Atlanta, Georgia

R. Patkar, Georgia Institute of Technology, Atlanta, Georgia

M. Betancur, Georgia Institute of Technology, Atlanta, Georgia

G. B. Stanley, Georgia Institute of Technology, Atlanta, Georgia

R. V. Bellamkonda, Georgia Institute of Technology, Atlanta, Georgia

493

Controlled release of Chondroitinase ABC to the injured spinal cord

biomolecular engineering; controlled release

M. Pakulska, University of Toronto, Toronto, ON, Canada

494

Decellularized Equine Sciatic Nerve Hydrogel for Peripheral Nerve Repair

biocompatibility/soft tissue; cell-material interactions; nerve regeneration

S. T. LoPresti, University of Pittsburgh, Pittsburgh, PA

495

Basement Membrane-Polycaprolactone Blend Nanofibers as a Scaffold for Tissue Engineering

biomimetic; extracellular matrix; nerve regeneration

S. Lenz, University of Virginia, Charlottesville, VA

R. Neal, University of Virginia, Charlottesville, Virginia

D. Abebayehu, University of Virginia, Charlottesville, Virginia

B. Brooks, University of Virginia, Charlottesville, Virginia

R. C. Ogle, LifeNet Institute of Regenerative Medicine, Norfolk, Virginia

E. Botchwey, Georgia Institute of Technology, Atlanta, Georgia

496

Microspheres for sustained delivery of NEP1-40 and chondroitinase ABC for treatment of spinal cord injury

drug delivery/release; nerve regeneration

T. Wilems, Washington University, St. Louis, MO

D. McCreedy, Washington University, St.Louis, Missouri

L. Marquardt, Washington University, St. Louis, Missouri

S. E. Sakiyama-Elbert, Washington University, St. Louis, Missouri

497

Decellularized Equine Sciatic Nerve as a Scaffold for Peripheral Nerve Repair

absorbable

T. Prest, University of Pittsburgh, Pittsburgh, PA

498

Electrically Conductive Nerve Guidance Channel

electrical stimulation; nerve regeneration; neural prosthesis

Z. Zhang, Laval University, Quebec, QC, Canada

Z. Du, Laval University, Quebec, Québec, Canada

913

Photoreactive Interpenetrating Network with Tunable Stiffness as a Scaffold for Neurite Growth

hydrogel; nerve regeneration; tissue engineering

P. Khoshakhlagh, Tulane University, New orleans, LA

E. L. Horn-Ranney, Tulane University, New Orleans, Louisiana

M. J. Moore, Tulane University, New Orleans, Louisiana

Biomaterial Strategies for Large-Area Bone Regeneration

499

Effect of novel putty-like resorbable calcium alkali orthophosphate bone substitute cements designed for restoring contours in craniofacial surgery on bone formation and osteoblastic phenotype expression in vivo

bioactive material; bone; craniofacial

C. Knabe, Philipps University Marburg, Marburg, Germany

G. Berger, Federal Institute for Materials Research and Testing, Berlin, Germany

R. Gildenharr, Federal Institute for Materials Research and Testing, Berlin, Germany

F. Dombrowski, Federal Institute for Materials Research and Testing, Berlin, Germany

K. Reiter, Philipps University Marburg, Marburg, Germany

A. Houshmand, Philipps University Marburg, Marburg, Germany

M. Stiller, Philipps University Marburg, Marburg, Germany

500

Vascular endothelial growth factor expression in posterolateral rabbit fusion:  An evaluation of bone graft materials

angiogenesis/neovascularization; animal model; bone graft

F. V. Lamberti, Pioneer Surgical, Greenville, NC

W. R. Walsh, University of New South Wales, Syndey, Australia

R. A. Oliver, University of New South Wales, Sydney, Australia

Y. Yu, University of New South Wales, Sydney, Australia

B. Schlossberg, Pioneer Surgical, Woburn, Massachusetts

503

Developing Polymer/Ceramic Scaffolds using a Factorial Design of Experiments and Response-surface Analysis

ceramic; polymer; scaffolds

J. A. Minton, Miami University, Hamilton, OH

C. Janney, Miami University, Oxford, Ohio

C. Focke, Miami University, Oxford, Ohio

P. James, Miami University, Oxford, Ohio

A. Yousefi, Miami University, Oxford, Ohio

504

Comparison of beta-tricalcium phosphate foam made using Mg stabilizer and by heat treatment

calcium phosphate(s)

K. Ishikawa, Kyushu University, Fukuoka, Japan

T. Nikaido, Kyushu University, Fukuoka, Japan

K. Tsuru, Kyushu University, Fukuoka, Japan

505

Effect of Calcium Phosphate Coatings and Bone Morphogenetic Protein (BMP)-2 on In Vivo Bone Regeneration using 3-dimensional Poly (propylene fumarate) Scaffolds in Rabbit Calvarial Model

animal model; bone ingrowth; calcium phosphate(s)

M. Dadsetan, Mayo Clinic, Rochester, MN

506

Testing of a Bioactive, Moldable Bone Graft Substitute in an Infected, Critically-Sized Defect Model

bone graft; in vivo; infection

M. Brown, University of Kentucky, Lexington, KY

Y. Zou, University of Kentucky, Lexington, Kentucky

R. Peyyala, University of Kentucky, Lexington, Kentucky

T. Milbrandt, University of Kentucky, Lexington, Kentucky

L. Cunningham, University of Kentucky, Lexington, Kentucky

T. Dziubla, University of Kentucky, Lexington, Kentucky

D. Puleo, University of Kentucky, Lexington, Kentucky

507

Performance of polymer + OCP composite scaffolds in the CSD rabbit calvaria model

bone; calcium phosphate(s); in vivo

O. Ortiz, Rutgers - The State University of New Jersey, Piscataway, NJ

R. Z. LeGeros, New York University, New York, New York

J. Kohn, Rutgers - The State University of New Jersey, Piscataway, New Jersey

508

Improving Transport Limitations of Tissue Engineered Bone Scaffolds

bone graft

S. Tabbaa, Clemson University, Clemson, SC

509

The Effect of Wicking Fibers on Transport Properties of Tissue Engineered Scaffolds

scaffolds; tissue engineering; vascular graft

S. Tabbaa, Clemson University, Clemson, SC

510

A Novel Approach to Engineer Vascularized Osteon-like Constructs for Cortical Bone Tissue Engineering

biomimetic; bone; bone graft

X. Chen, Stevens Institute of Technology, Hoboken, NJ

H. Wang, Stevens Institute of Technology, Hoboken, New Jersey

914

Surface Modified Chitosan Tissue Engineering Scaffolds for Biomimetic Periosteum on Cortical Bone Allografts

biomimetic; bone graft; tissue engineering

R. Romero, Colorado State University, Fort Collins, CO

M. J. Kipper, Colorado State University, Fort Collins, Colorado

Biomaterials and Medical Product Commercialization

511

A novel technique for micromotion measurement of unicompartmental tibial trays for design comparison

orthopedic

G. Yildirim, Pipeline Orthopedics, Cedar Knolls, NJ

915

Fabrication and Tissue Anchoring performance of Nylon and Polypropylene Barbed Surgical Sutures

suture

H. Cong, North Carolina State University, Raleigh, NC

S. Roe, North Carolina State University, Raleigh, North Carolina

M. King, North Carolina State University, Raleigh, North Carolina

P. Mente, North Carolina State University, Raleigh, North Carolina

G. Ruff, 4Vilcom Circle, Chapel Hill, Raleigh, North Carolina

916

Reduction of Absorption Time for a Polydioxanone Homopolymer Using Polyethylene glycol

bioresorbable; block copolymer; suture

D. R. Ingram, Poly-Med, Inc., Anderson, SC, SC

Biomaterials Design and Tissue Engineering via Synthetic Biology

513

Multiscale Organization of Nanofiber-based Structures: Nature Design, Bio-inspired Engineering and Future Directions

biomimetic; biomolecular engineering; fiber

C. Zhong, Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA

T. K. Lu, Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts

Biomaterials Education

515

Biomaterial Implant Design Competition for High School Students

biomaterials availability; bone; education/instruction

A. C. Parker, The University of Memphis, Memphis, TN

J. M. Goodhart, The University of Memphis, Memphis, Tennessee

T. Phung, The University of Memphis, Memphis, Tennessee

J. Williams, The University of Memphis, Memphis, Tennessee

J. D. Bumgardner, The University of Memphis, Memphis, Tennessee

516

Alternative Methods to Determine Extractable Monomer Content of Polydioxanone (PDO)

bioresorbable; polydioxanone; polymer

C. Culbreath, Poly-Med, Inc., Anderson, SC

J. Olbrich, Poly-Med, Inc., Anderson, South Carolina

J. Corbett, Poly-Med, Inc., Anderson, South Carolina

517

Integrating creative thinking into biomaterials education: A first year bioengineering seminar module to teach how to design musculoskelatal bioengineering systems for regenerative purposes

scaffolds

T. Ozdemir, The Pennsylvania State University, University Park, PA

Biomaterials for Cardiac Repair

518

Development of Electrospun Hyaluronic Acid Scaffolds Containing Multivalent Peptide Conjugates

bioactive material; scaffolds

N. A. Rode, UC Berkeley, Oakland, CA

N. C. Marks, UC Berkeley, Berkeley, California

K. E. Healy, UC Berkeley, Berkeley, California

917

Stem Cell Therapy in Heart Failure: Application Strategies for the CardioCel® Matrix

cardiovascular; cell culture; collagen

J. A. M. Ramshaw, CSIRO, Clayton, Australia

A. Vashi, CSIRO, Clayton, Australia

J. F. White, CSIRO, Clayton, Australia

K. M. McLean, CSIRO, Clayton, Australia

W. M. L. Neethling, University of Western Australia, Fremantle, Australia

J. A. Werkmeister, CSIRO, Clayton, Australia

Biomaterials for Modulating Immune and Inflammatory Processes

519

Distinct Local Macrophage Phenotypes Are Associated With Divergent Tissue Remodeling Outcomes Following Implantation of Biologic Scaffolds

immune response

B. N. Brown, McGowan Institute for Regenerative Medicine, Pittsburgh, PA

K. A. Kukla, Carnegie Mellon University, Pittsburgh, Pennsylvania

B. M. Sicari, McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania

N. J. Turner, McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania

L. Zhang, McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania

S. F. Badylak, McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania

520

How Estrogen Receptor Signaling Modulates the Response of Human Macrophages to Wear Particles

inflammation; osteolysis; wear debris

C. Li, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA

C. Nich, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California

J. K. Antonios, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California

Z. Yao, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California

K. Kealoha-Steck, Department of Pathology, Stanford University School of Medicine, Stanford, California

M. Fontaine, Department of Pathology, Stanford University School of Medicine, Stanford, California

S. B. Goodman, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California

521

Composition of Intraperitoneal Electrospun Conduits Influence Recruited Cell Phenotype and Matrix Synthesis

animal model; cardiovascular; wound healing

C. A. Bashur, Cleveland Clinic, Cleveland, OH

M. J. Eagleton, Cleveland Clinic, Cleveland, Ohio

A. Ramamurthi, Cleveland Clinic, Cleveland, Ohio

522

Bliateral regulation of human monocytes and matrix-encapsulated mesenchymal stromal/stem cells in vitro and in full-thickness cutaneous wounds

encapsulated cells; inflammation; wound healing

D. A. Cantu, University of Wisconsin-Madison, Madison, WI

523

Chitosan Particles Induce Human U937 Macrophages to Release Anti-Inflammatory Factors and Mesenchymal Stem Cell Chemokines Through Pathways Involving STAT-1

regenerative medicine; stem/progenitor cells; wound healing

D. Fong, École Polytechnique de Montréal, Montréal, QC, Canada

M. B. Ariganello, École Polytechnique de Montréal, Montréal, Québec, Canada

J. Girard-Lauzière, École Polytechnique de Montréal, Montréal, Québec, Canada

C. D. Hoemann, École Polytechnique de Montréal, Montréal, Québec, Canada

524

Modulation of in vitro nitric oxide production in murine macrophages by immobilized and soluble glycosaminoglycans

cell-material interactions; extracellular matrix; inflammation

G. Tan, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

Y. Tabata, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

525

Development of Controlled Drug-Releasing Constructs to Mediate Inflammation in an Islet Transplant Site

diabetes; drug delivery/release; immune response

J. D. Weaver, University of Miami, Miami, FL

Y. Song, University of Miami, Miami, Florida

A. Pileggi, University of Miami, Miami, Florida

P. Buchwald, University of Miami, Miami, Florida

C. L. Stabler, University of Miami, Miami, Florida

526

Time Course of Macrophage Polarization in Response to Wear Particles in vitro

bone cement (= PMMA, acrylic); immune response; osteolysis

J. K. Antonios, Stanford University School of Medicine, Stanford, CA

C. Li, Stanford University School of Medicine, Stanford, California

Z. Yao, Stanford University School of Medicine, Stanford, California

A. J. Rao, Stanford University School of Medicine, Stanford, California

S. B. Goodman, Stanford University School of Medicine, Stanford, California

527

Vascularization for Bone Tissue Engineering through Modulation of Macrophage Behavior

angiogenesis/neovascularization; immune response; inflammation

K. L. Spiller, Columbia University, New York, NY

R. Anfang, Columbia University, New York, New York

J. Ng, Columbia University, New York, New York

K. Nakazawa, Columbia University, New York, New York

G. Vunjak-Novakovic, Columbia University, New York, New York

528

Polyanhydride particle vaccine platform enhances antigen-specific cytotoxic T cell responses

drug delivery/release; immune response; polymer

K. Ross, Iowa State University, Ames, IA

L. Huntimer, Iowa State University, Ames, Iowa

R. Darling, Iowa State University, Ames, Iowa

A. Ramer-Tait, Iowa State University, Amesq, Iowa

B. Narasimhan, Iowa State University, Ames, Iowa

M. Wannemuehler, Iowa State University, Ames, Iowa

529

Deposition and Persistence of Polyanhydride Nanoparticle Vaccines upon Intranasal Administration

drug delivery/release; nanotechnology; sustained release

K. Ross, Iowa State University, Ames, IA

S. Haughney, Iowa State University, Ames, Iowa

T. Brenza, Iowa State University, Ames, Iowa

L. Huntimer, Iowa State University, Ames, Iowa

P. Boggiatto, Iowa State University, Ames, Iowa

M. Wannemuehler, Iowa State University, Ames, Iowa

B. Narasimhan, Iowa State University, Ames, Iowa

530

Humoral responses elicited by polyanhydride nanoparticle formulations are facilitated by enhanced CD4+ T cell helper cells

drug delivery/release; immune response; polymer

K. Ross, Iowa State University, Ames, IA

L. Huntimer, Iowa State University, Ames, Iowa

R. Darling, Iowa State University, Ames, Iowa

A. Ramer-Tait, Iowa State University, Ames, Iowa

B. Narasimhan, Iowa State University, Ames, Iowa

M. Wannemuehler, Iowa State University, Ames, Iowa

531

Polyanhydride Nanoparticle-based Influenza Vaccine Elicits Viral Neutralizing Titers and Enhances Cell-Mediated Immunity

drug delivery/release; immune response; polymer

K. Ross, Iowa State University, Ames, IA

L. Huntimer, Iowa State University, Ames, Iowa

W. Wu, Iowa State University, Ames, Iowa

S. Carpenter, Iowa State University, Ames, Iowa

B. Narasimhan, Iowa State University, Ames, Iowa

M. Wannemuehler, Iowa State University, Ames, Iowa

532

Enhancing Mechanical Properties of Fibrin Matrices for Wound Healing Applications through Optimized B-knob Engagement

fibrin

K. C. Clause, Georgia Institute of Technology, Atlanta, GA

533

Investigation of interaction between the dynamic polymer surfaces and collagen molecules

collagen; polymer; surface modification

K. Nam, Tokyo Medical and Dental University, Tokyo, Japan

J. Seo, Tokyo Medical and Dental University, Tokyo, Japan

T. Kimura, Tokyo Medical and Dental University, Tokyo, Japan

N. Yui, Tokyo Medical and Dental University, Tokyo, Japan

A. Kishida, Tokyo Medical and Dental University, Tokyo, Japan

534

Specific cytokines released by monocytes cultured on a degradable polyurethane (D-PHI) influence VSMC response

cardiovascular; cytokines; vascular

K. Battiston, University of Toronto, Toronto, ON, Canada

B. Ouyang, University of Toronto, Toronto, Ontario, Canada

R. Labow, University of Ottawa Heart Institute, Ottawa, Ontario, Canada

C. Simmons, University of Toronto, Toronto, Ontario, Canada

J. Santerre, University of Toronto, Toronto, Ontario, Canada

535

Cell-Specific ECM Down-Regulates the Inflammatory Response to Nervous System Implants

immunohistochemistry; inflammation; tissue engineering

M. B. Christensen, University of Utah, Salt Lake City, UT

J. L. Skousen, University of Utah, Salt Lake City, Utah

N. Khan, University of Utah, Salt Lake City, Utah

P. A. Tresco, University of Utah, Salt Lake City, Utah

536

Microstructured Immunoregulatory Scaffolds for Controlling Host-Biomaterial Interactions

cell-material interactions; cytokines; scaffolds

N. Washburn, Carnegie Mellon University, Pittsburgh, PA

M. Ramadan, Carnegie Mellon University, Pittsburgh, Pennsylvania

T. Hinton, Carnegie Mellon University, Pittsburgh, Pennsylvania

A. Feinberg, Carnegie Mellon University, Pittsburgh, Pennsylvania

537

Polyanhydride nanoparticle vaccine platform delays tumor growth in an antigen specific model

immune response; nanomedicine; tumor

R. Darling, Iowa State University, Ames, IA

538

Ultra Strong, Thermoresponsive Double-Network Hydrogels

biocompatibility/soft tissue; smart materials

R. Fei, Texas A&M University, Bryan, TX

M. A. Grunlan, Texas A&M University, College Station, Texas

539

Controlled Nitric Oxide Releasing Dendronized Poly(vinyl chloride) for Improving Biocompatibility of Implantable Devices

controlled release; polymer

S. P. Hopkins, Michigan Technological University, Houghton, MI

540

Novel h9e Peptide Sequence for Medical Uses

blood-material interaction; hydrogel

T. L. Carter, Kansas State University, Manhattan, KS

541

Modulation of Host Response by Anti-inflammatory Drugs to Improve the Efficacy of Immuno-isolated Islets in Diabetes Therapy

diabetes; drug delivery/release; foreign body reactions (response)

T. T. Dang, Massachusetts Institute of Technology, Cambridge, MA

A. V. Thai, Massachusetts Institute of Technology, Cambridge, Massachusetts

J. Cohen, Joslin Diabetes Center, Boston, Massachusetts

J. E. Slosberg, Massachusetts Institute of Technology, Cambridge, Massachusetts

K. Siniakowicz, Joslin Diabetes Center, Boston, Massachusetts

J. C. Doloff, Massachusetts Institute of Technology, Cambridge, Massachusetts

M. Ma, Massachusetts Institute of Technology, Cambridge, Massachusetts

J. Hollister-Lock, Joslin Diabetes Center, Cambridge, Massachusetts

K. Tang, Massachusetts Institute of Technology, Cambridge, Massachusetts

Z. Gu, Massachusetts Institute of Technology, Cambridge, Massachusetts

H. Cheng, Massachusetts Institute of Technology, Cambridge, Massachusetts

G. C. Weir, Joslin Diabetes Center, Boston, Massachusetts

R. Langer, Massachusetts Institute of Technology, Cambridge, Massachusetts

D. G. Anderson, Massachusetts Institute of Technology, Cambridge, Massachusetts

542

Magnetic Resonance Imaging Tracking of Dendritic Cells Homing to the Draining Lymph Nodes in Mice

molecular imaging; nanomaterials/nanophase; nanomedicine

Y. Xu, Sichuan University, Chengdu, China

D. Wang, Sichuan University, Chengdu, China

Y. Liu, Sichuan University, Chengdu, China

C. Xia, West China Hospital, Sichun University, Chengdu, China

Q. Gong, West China Hospital, Sichuan University, Chengdu, China

B. Song, West China Hospital, Sichuan University, Chengdu, China

C. Wu, Sichuan University, Chengdu, China

G. Lin, Sichuan University, Chengdu, China

D. Li, Sichuan University, Chengdu, China

H. Ai, Sichuan University, Chengdu, China

543

Thermally stable self-adjuvanting vaccines via self-assembling peptides

immune response; stability

T. Sun, University of Chicago, Chicago, IL

544

Decoy Protein Delivery from Titanium Implants

coating(s); inflammation; wear debris

M. Keeney, Stanford University, Stanford, CA

Z. Yao, Stanford University, Stanford, California

K. Egashira, Kyushu University, Fukuoka, Japan

S. B. Goodman, Stanford University, Stanford, California

F. Yang, Stanford University, Stanford, California

545

Orthopaedic Wear Particle Disease and NFκB Signaling

cell-material interactions; inflammation; wear debris

Z. Yao, Stanford University School of Medicine, Stanford, CA

M. Keeney, Stanford University School of Medicine, Stanford, California

J. K. Antonios, Stanford University School of Medicine, Stanford, California

C. Li, Stanford University School of Medicine, Stanford, California

R. L. Smith, Stanford University School of Medicine, Stanford, California

F. Yang, Stanford University School of Medicine, Stanford, California

K. Egashira, Kyushu University, Fukuoka, Japan

S. B. Goodman, Stanford University School of Medicine, Stanford, California

Biomaterials for Triggered Delivery to the Cytosol

546

Polycationic Hydrogel Nanoparticles for siRNA Delivery

controlled release; drug delivery/release; gene therapy/gene delivery

D. C. Forbes, The University of Texas at Austin, Austin, TX

D. C. Forbes, The University of Texas at Austin, Austin, Texas

H. Frizzell, The University of Texas at Austin, Austin, Texas

B. Carrillo-Conde, The University of Texas at Austin, Austin, Texas

N. A. Peppas, The University of Texas at Austin, Austin, Texas

547

Redox Responsive Polymeric Nanocapsules for Protein Delivery

nanomaterials/nanophase; polymer

M. Zhao, University of California, Los Angeles, Los Angeles, CA

Y. Tang, University of California Los Angeles, Los Angeles, California

548

Ultrasonically Activated Delivery to the Cytosol using Acoustic Droplet Vaporization

cell therapy; controlled release; drug delivery/release

W. G. Pitt, Brigham Young University, Provo, UT

J. R. Lattin, Brigham Young University, Provo, Utah

M. J. McRae, Brigham Young University, Provo, Utah

K. Moake, Brigham Young University, Provo, Utah

Biomaterials in Medical Device Recycling and Reprocessing

549

Toward a heat-curling polymeric needle designed for safe disposal

mechanical properties; polymer; smart materials

P. Yang, Syracuse University, Syracuse, NY

P. T. Mather, Syracuse University, Syracuse, New York

918

Encapsulation of antigen in chitosan particles enhances activation and antigen specific response by antigen presenting cells

drug delivery/release; immune response; in vitro

B. Koppolu, University of Arkansas, Fayetteville, AR

D. A. Zaharoff, University of Arkansas, Fayetteville, Arkansas

919

Transplantable Matrix Permits T Cell and Dendritic-Fusion Cell Interaction

cell-cell interactions; immune response

K. M. Charoen, Boston University, Boston, MA

T. Konry, Shriners Childrens Hospitals, Boston, Massachusetts

S. Cohen, Ben Gurion University, Negev, Israel

D. Avigan, Beth Israel/Deaconess Medical Center, Boston, Massachusetts

M. Yarmush, Shriners Hospitals for Children, Boston, Massachusetts

M. W. Grinstaff, Boston University, Boston, Massachusetts

920

Study on the Antimicrobial Properties of a High Copper Content Zr-based Bulk Metallic Glass

antimicrobial

W. He, The University of Tennessee, Knoxville, TN

L. Huang, The University of Tennessee, Knoxville, Tennessee

E. Fozo, The University of Tennessee, Knoxville, Tennessee

P. Liaw, The University of Tennessee, Knoxville, Tennessee

Biomaterials in the Fourth Dimension – Controlling Temporal Properties

550

Fabrication of a Light-Emitting Shape Memory Polymeric Web

polymer; smart materials

A. H. Torbati, Syracuse University, Jamesville, NY

551

Controlled Guidance of Spinal Motor Axons through Synthetic Click Hydrogels

cell-material interactions; neurons; polymerization

D. D. McKinnon, University of Colorado at Boulder, Boulder, CO

552

Characterization of Dynamic Shape-Memory (Meth)Acrylate Networks for Tissue Engineering Applications

polymer; smart materials; surface characterization

E. Hewett, Georgia Institute of Technology, Atlanta, GA

K. Smith, MedShape Solutions, Inc., Atlanta, Georgia

K. Gall, Georgia Institute of Technology, Atlanta, Georgia

Z. Schwartz, Georgia Institute of Technology, Atlanta, Georgia

B. D. Boyan, Georgia Institute of Technology, Atlanta, Georgia

553

Smart Supramolecular Hydrogels encapsulated Bioengineered Stem Cells for Cancer Therapy

cell therapy; controlled release; stem/progenitor cells

J. Yeom, POSTECH, Pohang, Republic of Korea

S. Kim, POSTECH, Pohang, Republic of Korea

H. Jung, POSTECH, Pohang, Republic of Korea

H. Namgung, POSTECH, Pohang, Republic of Korea

J. Yang, POSTECH, Pohang, Republic of Korea

K. Kim, POSTECH, Pohang, Republic of Korea

Y. Sung, POSTECH, Pohang, Republic of Korea

S. Hahn, POSTECH, Pohang, Republic of Korea

554

Signal-processing Biomaterials

controlled release; hydrogel; smart materials

K. Jakobus, University of Freiburg, Freiburg, Germany

W. Weber, University of Freiburg, Freiburg, Germany

555

Gellan gum-based Spongy-like Hydrogels depict improved Cellular Performance

cell adhesion; cell-material interactions; hydrogel

L. P. da Silva, University of Minho (Portugal), Guimarães, Portugal

M. T. Cerqueira, University of Minho, Guimarães, Portugal

R. A. Sousa, University of Minho, Guimarães, Portugal

A. P. Marques, University of Minho, Guimarães, Portugal

V. M. Correlo, University of Minho, Guimarães, Portugal

R. L. Reis, University of Minho, Guimarães, Portugal

556

Smart Nanofiber Webs for “On-off” Release of Cells and Drugs

smart materials

M. Ebara, National Institute for Materials Science, Tsukuba, Japan

T. Aoyagi, National Institute for Materials Science, Tsukuba, Japan

557

A Novel Platform for On Demand Delivery of Multiple Proteins

controlled release; hydrogel; smart materials

N. Mokarram, Georgia Institute of Technology and Emory University, Atlanta, GA

A. Merchant, Georgia Institute of Technology and Emory University, Atlanta, Georgia

R. Bellamkonda, Georgia Institute of Technology and Emory University, Atlanta, Georgia

558

Dynamic Photo-Tunable Gels to Modulate Matrix Stiffness

hydrogel; matrix; mechanical properties

R. S. Stowers, The University of Texas at Austin, Austin, TX

C. L. Davis, The University of Texas at Austin, Austin, Texas

B. Han, The University of Texas at Austin, Austin, Texas

L. J. Suggs, The University of Texas at Austin, Austin, Texas

921

Shape-memory Surfaces facilitate Time-dependent Observation of Cell Functions

cell-material interactions; smart materials

K. Uto, National Institute for Materials Science (NIMS), Tsukuba, Japan

M. Ebara, National Institute for Materials Science (NIMS), Tsukuba, Japan

T. Aoyagi, National Institute for Materials Science (NIMS), Tsukuba, Japan

Biomaterials to Decode Cell-Cell Signaling

559

Hydrogel-based Platforms for Co-Culture and On-Demand Cell Retrieval of Human Mesenchymal Stem Cells

biodegradation; cell-cell interactions; hydrogel

T. E. Rinker, Georgia Institute of Technology and Emory University, Atlanta, GA

T. M. Hammoudi, Georgia Institute of Technology and Emory University, Atlanta, Georgia

H. Lu, Georgia Institute of Technology, Atlanta, Georgia

J. S. Temenoff, Georgia Institute of Technology and Emory University, Atlanta, Georgia

Biomimetic Surfaces: From Multi-scale Fabrication Methods to Diagnostic, Therapeutic and Clinical Applications

560

Vascularized Biomaterials for Rapid Soft-Stiff Transitions in Medical Devices

biomimetic; polymer

A. Balasubramanian, Carnegie Mellon University, Pittsburgh, PA

C. Bettinger, Carnegie Mellon University, Pittsburgh, Pennsylvania

561

Reinforcement of Calcium Phosphate Cement Using Silk Fibroin (SF) and Self-assembled SF-Hydroxyapatite Complex

absorbable; biomimetic; calcium phosphate(s)

B. Li, Soochow University, Suzhou, Jiangsu Province, China

562

Clickable PEG nanogel coatings compared to PEG/BSA nanogels: synergy between PEG and BSA contributes to ultralow protein adsorption as assessed by single molecule fluorescence

adsorption

D. L. Elbert, Washington University in St. Louis, St. Louis, MO

C. D. Donahoe, Washington University in St. Louis, St. Louis, Missouri

563

Mucin Layers as Biomimetic Coating for Polymeric Biomaterials

biomimetic; coating(s); protein adsorption

S. Lee, Technical University of Denmark, Kgs. Lyngby, Denmark

Cardiovascular Biomaterials

564

Design, Preparation and in vitro Assay of a Novel Endothelial Progenitor Cell Capturing Vascular Prosthesis

protein adsorption; surface modification; vascular prosthesis

B. Li, Laval University, Quebec City, QC, Canada

Z. Zhang, Laval University, Quebec, Québec, Canada

X. Xie, Sichuan University, Chengdu, China

Y. Zhong, Sichuan University, Chengdu, China

R. Guidoin, Laval University, Quebec, Québec, Canada

Y. Douville, Laval University, Québec, Québec, Canada

565

pH neutralization and inflammation prevention by RA and PLLA-grafted magnesium hydroxide nanoparticles

surface modification

D. Han, Korea Institute of Science and technology, Seoul, Republic of Korea

566

Improvement of Interfacial Adhesion by ATRP and Stereocomplex for Drug-Eluting Stents

surface modification

D. Han, Korea Institute of Science and Technology, Seoul, Republic of Korea

567

Optimization and characterization of a new injectable radiopaque chitosan-based embolizing hydrogel for endovascular therapies

embolization; hydrogel; vascular

F. Zehtabi, École de technologie supérieure, Montreal, QC, Canada

568

Characterization and Optimization of Nanoliposomes to Deliver 17β-Estradiol

cardiovascular; controlled release; cytotoxicity

K. Bowey, McGill University, Montreal, QC, Canada

I. Cloutier, Montreal Heart Institute, Montreal, Québec, Canada

J. Tanguay, Montreal Heart Institute, Montreal, Québec, Canada

M. Tabrizian, McGill University, Montreal, Québec, Canada

569

Superior in vivo biocompatibility of a hydrophilic polymer coated prosthetic vascular graft

blood-material interface; endothelialization; vascular prosthesis

M. L. W. Knetsch, Maastricht University, Maastricht, Netherlands

570

Hyaluronic Acid Enhancement of Polyethylene for Cardiovascular Applications

blood-material interface; cardiovascular; mechanical properties

N. Lewis, Colorado State University, Fort Collins, CO

571

Functionalization of Nonwoven Poly(Ethylene Terephthalate) Structures Designed as Compliant Small-Diameter Vascular Grafts

mechanical properties; surface modification; vascular graft

S. Noel, Ecole Polytechnique de Montreal, Montréal, QC, Canada

B. Liberelle, Ecole Polytechnique de Montréal, Montréal, Québec, Canada

A. Yogi, National Research Council Canada, Ottawa, Ontario, Canada

M. J. Moreno, National Research Council Canada, Ottawa, Ontario, Canada

M. N. Bureau, National Research Council Canada, Boucherville, Québec, Canada

L. Robitaille, National Research Council Canada, Boucherville, Québec, Canada

G. De Crescenzo, Ecole Polytechnique de Montréal, Montréal, Québec, Canada

572

Functional macromolecules for simple surface modification of a biodegradable magnesium alloy to reduce thrombogenicity and improve corrosion resistance

corrosion; hemocompatibility; surface modification

S. Ye, University of Pittsburgh, Pittsburgh, PA

V. Shankarraman, University of Pittsburgh, Pittsburgh, Pennsylvania

Y. Jang, North Carolina A&T State University, Greensboro, North Carolina

H. Sakaguchi, Toray Co LtD, Pittsburgh, Pennsylvania

Y. Yun, North Carolina A&T State University, Greensboro, North Carolina

W. R. Wagner, University of Pittsburgh, Pittsburgh, Pennsylvania

573

Impact of Age on Bovine Pericardial Composition and Mechanics

biomechanics; heart valve; pericardium

T. J. Tod, Edwards Lifesciences, Irvine, CA

J. R. Yamada, Edwards Lifesciences, Irvine, California

J. A. Benton, Edwards Lifesciences, Irvine, California

574

Fabrication and Mechanical Evaluation of Bicomponent PET/Silk Small Diameter Arterial Prostheses

cardiovascular

X. Yang, Key Lab of Textile Science and Technology, College of Textiles, Donghua University, Shanghai, 201620, ChinaCollege of Textiles, North Carolina State University, Raleigh 27695, USA, Raleigh, NC

L. Wang, Key Lab of Textile Science and Technology, College of Textiles, Donghua University, Shanghai, 201620, China, Shanghai, China

M. W. King, Key Lab of Textile Science and Technology, College of Textiles, Donghua University, Shanghai, 201620, China, Raleigh, North Carolina

G. Guan, Key Lab of Textile Science and Technology, College of Textiles, Donghua University, Shanghai, 201620, China, Shanghai, China

Y. Guan, Key Lab of Textile Science and Technology, College of Textiles, Donghua University, Shanghai, 201620, China, Shanghai, China

575

Synthesis of Polycarbonate Urethanes with Functional Poly(ethylene glycol) Side Chains Intended for Bioconjugation

cardiovascular; polyurethane(s)

X. Xie, Sichuan University, Chengdu, China

Q. Fu, Sichuan University, Chengdu, China

Y. Zhong, Sichuan University, Chengdu, China

Z. Zhang, Université Laval, Quebec City, Québec, Canada

Y. Xu, Sichuan University, Chengdu, China

576

Magnetic Capture of Endothelial Cells to Vascular Stents Within An Externally Applied Magnetic Field

endothelial cells; tissue engineering; vascular stents

B. J. Tefft, Mayo Clinic, Rochester, MN

S. Uthamaraj, Mayo Clinic, Rochester, Minnesota

J. Y. Gooden, Mayo Clinic, Rochester, Minnesota

J. J. Harburn, Durham University, Stockton, United Kingdom (Great Britain)

M. Klabusay, St. Anne's University Hospital, Brno, Czech Republic

D. R. Holmes, Jr., Mayo Clinic, Rochester, Minnesota

R. D. Simari, Mayo Clinic, Rochester, Minnesota

D. Dragomir-Daescu, Mayo Clinic, Rochester, Minnesota

G. S. Sandhu, Mayo Clinic, Rochester, Minnesota

922

Development of a Shape Memory Patch for Minimally Invasive Repair of Vascular Rupture

scaffolds; smart materials; vascular

T. Boire, Vanderbilt University, Nashville, TN

923

Cardiac Lead Retrieval Analysis: Insulation Degradation Hinders Long Term Performance

biodegradation; heart assist device; polyurethane(s)

M. Tohfafarosh, Drexel University, Philadelphia, PA

A. Sevit, Drexel University, Philadelphia, Pennsylvania

J. Patel, Exponent Inc., Phialdelphia, Pennsylvania

A. Greenspon, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

J. M. Prutkin, University of Washington, Seattle, Washington

S. Kurtz, Drexel University, Philadelphia, Pennsylvania

Ceramics and Composites in Bone Tissue Engineering and Drug Delivery

577

Bilayered Calcium Sulfate Space-Making Composites with Multiple Drug Delivery Capabilities

composite/hard tissue; controlled release; dental/craniofacial material

B. R. Orellana, University of Kentucky, Lexington, KY

M. V. Thomas, University of Kentucky, Lexington, Kentucky

J. Z. Hilt, University of Kentucky, Lexington, Kentucky

D. Puleo, University of Kentucky, Lexington, Kentucky

578

Fabrication of Customized Porous Hydroxyapatite (HA) implants for Osteotomy

bone marrow; hydroxy apatite; orthopedic

H. Jung, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea

T. Jang, Department of Materials Science and Engineering, Seoul National University, Department of Materials Science and Engineering, Seoul National University, Republic of Korea

M. Kang, Department of Materials Science and Engineering, Seoul National University, Department of Materials Science and Engineering, Seoul National University, Republic of Korea

S. Kim, Seoul National Univ., seoul, Republic of Korea

H. Kim, Department of Materials Science and Engineering, Seoul National University, Department of Materials Science and Engineering, Seoul National University, Republic of Korea

Y. Koh, Department of Materials Science and Engineering, Seoul National University, bDepartment of Dental Laboratory Science and Engineering, Korea University, Republic of Korea

Y. Estrin, Department of Materials Engineering, Monash University, Clayton, Australia, cDepartment of Materials Engineering, Monash University, Clayton, Australia, Republic of Korea

579

Cell Growth on a Gradient Calcium Polyphosphate Scaffold in a Perfusion Bioreactor

bone graft; calcium phosphate(s); cell culture

L. Chen, Wayne State University, Detroit, MI

581

Synthesis and Characterization of Amorphous Magnesium Phosphate: A Novel Bone Cement Precursor

biocompatibility/hard tissue; ceramic; surface characterization

N. Ostrowski, University of Pittsburgh, Pittsburgh, PA

B. Lee, University of Pittsburgh, Pittsburgh, Pennsylvania

N. Enick, University of Pittsburgh, Pittsburgh, Pennsylvania

A. Roy, University of Pittsburgh, Pittsburgh, Pennsylvania

P. N. Kumta, University of Pittsburgh, Pittsburgh, Pennsylvania

582

Comparative Properties of Gelatin/Synthetic Bone Mineral Composite and Bovine Bone

calcium phosphate(s)

R. Z. LeGeros, New York University, New York, NY

S. Saraswat, New York University, New York, New York

P. Khanna, New York University, New York, New York

D. Mijares, New York University, New York, New York

J. Dai, New York University, New York, New York

583

Effect of silica doping on microstructral and biological properties of brushite cements

bone remodeling; calcium phosphate(s); ceramic

S. Bose, Washington State University, Pullman, WA

S. Vahabzadeh, Washington State University, Pullman, Washington

M. Roy, Washington state university, Pull, Washington

A. Bandyopadhyay, Washington state university, Pullman, Washington

584

A Biomimetic Collagen-apatite Scaffold with Unique Multi-level Lamellar Structure for Bone Tissue Engineering

bone graft

Z. Xia, University of Connecticut, Coventry, CT

M. Wei, University of Connecticut, Storrs, Connecticut

Dental / Craniofacial Materials

585

Antimicrobial and Mechanical Properties of Bioactive Glass Reinforced Dental Composites

antimicrobial; bioactive glass; dental/craniofacial material

D. Khvostenko, Oregon State University, Corvallis, OR

J. Kruzic, Oregon State University, Corvallis, Oregon

J. Ferracane, Oregon Health and Science University, Portland, Oregon

J. Mitchell, Oregon Health and Science University, Portland, Oregon

586

Development of mandibular reconstruction device made of titanium fiber scaffold

bone; dental/craniofacial material; maxillofacial

M. Hirota, Yokohama City University Graduate School of Medicine, Yokohama, Japan

587

Effect of Seeding Density on Human Dental Pulp Cell Response in Polyethylene Glycol-Fibrinogen Hydrogel

dental/craniofacial material; fibrinogen; hydrogel

S. Prateepchinda, Columbia University, New York, NY

H. H. Lu, Columbia University, New York, New York

G. B. Hasselgren, Columbia University, New York, New York

D. Seliktar, Technion – Israel Institute of Technology, Haifa, Israel

588

Antibiotic-loaded Porous Poly(methyl methacrylate) for Space Maintenance and Local Drug Delivery

bone cement (= PMMA, acrylic); drug delivery/release; infection

S. R. Shah, Rice University, Houston, TX

S. Shah, Rice University, Houston, Texas

N. Raindel, Rice University, Houston, Texas

A. Henslee, Rice University, Houston, Texas

P. Spicer, Rice University, Houston, Texas

F. Kasper, Rice University, Houston, Texas

A. G. Mikos, Rice University, Houston, Texas

924

Three-Dimensionally Printed b-Tri-Calcium Phosphate/Hydroxyapatite-Bone Morphogenic Protein Scaffolds for Long Bone Regeneration

absorbable; biocompatibility/hard tissue; scaffolds

N. M. Tovar, New York University College of Dentistry, New York, NY

M. Sobieraj, Hospital for Joint Diseases, New York University Langone Medical Center, New York, New York

L. Witek, Oklahoma State University, Stillwater, Oklahoma

J. Smay, Oklahoma State University, Stillwater, Oklahoma

P. G. Coelho, New York University College of Dentistry, New York, New York

Developing the Next Generation of Cardiovascular Devices - From Concept to Implantation (An Industry Perspective)

589

Factors Affecting Distal Tip Stiffness of Pacemaker and Defibrillator Leads

implant design; mechanical properties; pacemaker

D. Walsh, U.S. Food and Drug Administration, Silver Spring, MD

B. Stephen, U.S. Food and Drug Administration, Silver Spring, Maryland

L. Topoleski, University of Maryland Baltimore County, Baltimore, Maryland

O. Vesnovsky, U.S. Food and Drug Administration, Silver Spring, Maryland

N. Duraiswamy, U.S. Food and Drug Administration, Silver Spring, MD, Maryland

590

Delivery of Vitamin-C (L-Ascorbic Acid) from Coronary Stent Material Surfaces

atomic force microscopy; cardiovascular; drug delivery/release

E. Thiruppathi, The University of South Dakota, Sioux Falls, SD

S. Kakade, The university of South Dakota, Sioux Falls, South Dakota

G. Mani, The university of South Dakota, Sioux Falls, South Dakota

591

A Nanofibrous Bioactive Vascular Graft for Small Vessel Reconstruction

bioactive material; nanotechnology; vascular graft

M. D. Phaneuf, BioSurfaces, Inc., Ashland, MA

S. G. Pathan, BioSurfaces, Inc., Ashland, Massachusetts

S. M. Ali, BioSurfaces, Inc., Ashland, Massachusetts

M. J. Bide, University of Rhode Island, Kingston, Rhode Island

D. W. Nelson, BioSurfaces, Inc., Ashland, Massachusetts

J. R. Araya, Northeastern University, Boston, Massachusetts

T. E. Phaneuf, BioSurfaces, Inc., Ashland, Massachusetts

T. M. Phaneuf, BioSurfaces, Inc., Ashland, Massachusetts

F. W. LoGerfo, Beth Israel Deaconess Medical Center, Boston, Massachusetts

M. A. Contreras, Beth Israel Deacones Medical, Boston, Massachusetts

592

A Novel Nitric Oxide-eluting  Nanocomposite Polymer for Cardiovascular Applications

cardiovascular; nanotechnology; vascular graft

N. Naghavi, University College London (UCL), London, United Kingdom (Great Britain)

925

Evaluation of Various Materials for Tip Penetration of Pacemaker and Defibrillator Leads

implant interface; mechanical properties; pacemaker

D. Walsh, U.S. Food and Drug Administration, Silver Spring, MD

B. Stephen, U.S. Food and Drug Administration, Silver Spring, Maryland

N. Duraiswamy, U.S. Food and Drug Administration, Silver Spring, Maryland

O. Vesnovsky, U.S. Food and Drug Administration, Silver Spring, Maryland

L. Topoleski, University of Maryland, Baltimore County, Baltimore, Maryland

Development, Analysis, and Design of Heart Valve Biomaterials - The State of The Art

593

Cell Injection Initiates the Recellularization Process in Decellularized Porcine Aortic Valve Scaffolds

cardiovascular; cell-material interactions; heart valve

D. B. Spoon, Mayo Clinic, Rochester, MN

B. J. Tefft, Mayo Clinic, Rochester, Minnesota

K. Coffman, Mayo Clinic, Rochester, Minnesota

S. Pan, Mayo Clinic, Rochester, Minnesota

D. Taylor, Texas Heart Institute, Houston, Texas

A. Lerman, Mayo Clinic, Rochester, Minnesota

R. D. Simari, Mayo Clinic, Rochester, Minnesota

594

Textile Heart Valve Prosthesis: Early In Vitro Fatigue Performances

heart valve; percutaneous

F. HEIM, Laboratoire de Physique et Mecanique Textiles, MULHOUSE, France

595

Valve Epithelial-to-Mesenchymal Transition is Enhanced on Composite Collagen-Hyaluronic Acid Hydrogels

cell-material interactions; endothelial cells; heart valve

M. Sewell-Loftin, Vanderbilt University, Nashville, TN

D. DeLaughter, Vanderbilt University, nashville, Tennessee

J. Barnett, Vanderbilt, Nashville, Tennessee

W. Merryman, Vanderbilt, nashville, Tennessee

596

A NOVEL MODEL FOR HEART VALVE BIOMATERIAL FATIGUE RESPONSE

biocompatibility/soft tissue; biomechanics; cardiovascular

M. S. Sacks, University of Texas at Austin, Austin, TX

W. Zhang, University of Texas at Austin, Austin, Texas

597

Fabrication of Advanced Poly(ethylene glycol) Diacrylate Hydrogels for Heart Valve Tissue Engineering

cell-material interactions; heart valve; tissue engineering

X. Zhang, Rice University, Houston, TX

B. Xu, Rice University, Houston, Texas

H. Tseng, Rice University, Houston, Texas

M. L. Cuchiara, Duke University, Durham, North Carolina

J. L. West, Duke University, Durham, North Carolina

J. K. Grande-Allen, Rice University, Houston, Texas

Drug Delivery

598

Nanoparticle-based Platform Enables Increased Intracellular Antibiotic Delivery and Killing of Brucella

antimicrobial; infection

B. H. Bellaire, Iowa State University, Ames, IA

Y. Phanse, Iowa State University, Ames, Iowa

P. Lueth, Iowa State University, Ames, Iowa

B. Narasimhan, Iowa State University, Ames, Iowa

599

Liposomal Delivery of FTY720 Modulates Inflammatory Response in Macrophages

drug delivery/release; inflammation

C. E. Segar, Georgia Institute of Technology and Emory University, Atlanta, GA

E. Botchwey, Georgia Institute of Technology and Emory University, Atlanta, Georgia

600

Antimicrobial Effectiveness of a Triclosan Coated Warp-Knit Mesh

absorbable; antimicrobial; drug delivery/release

G. Hilas, Poly-Med, Inc., Anderson, SC

K. Nichter, Poly-Med, Inc., Anderson, South Carolina

S. Peniston, Poly-Med, Inc., Anderson, South Carolina

S. Nagatomi, Poly-Med, Inc., Anderson, South Carolina

601

In vitro Studies of Silica Xerogels for Controlled, Sustained Gene Delivery

absorbable; controlled release; gene therapy/gene delivery

H. Qu, University of Pennsylvania, Philadelphia, PA

602

Effects of Ionic Dissolution Products of Bioceramics on the Structure and Bioactivity of Doxorubicin

cytotoxicity; drug delivery/release

H. Pacheco, University of North Carolina at Charlotte, Charlotte, NC

I. Nesmelova, University of North Carolina at Charlotte, Charlotte, North Carolina

D. Dréau, UNC Charlotte, Charlotte, North Carolina

A. El-Ghannam, UNC Charlotte, Charlotte, North Carolina

603

Administration Methods for Injectable Systems Involving Precipitation Mechanics

bioresorbable; drug delivery/release; polymer

J. Olbrich, Poly-Med, Inc., Anderson, SC

K. Gray, Poly-Med, Inc., Anderson, South Carolina

D. Ingram, Poly-Med, Inc., Anderson, South Carolina

S. Taylor, Poly-Med, Inc., Anderson, South Carolina

J. Corbett, Poly-Med, Inc., Anderson, South Carolina

604

Increased Efficacy of Doxorubicin Delivery with Phytosterol Nanoassemblies

drug delivery/release; nanobiology; nanomedicine

K. R. Fath, Queens College - City University of New York, Flushing, NY

S. H. Frayne, Fordham University, Bronx, New York

N. Nakatsuka, Fordham University, Bronx, New York

I. Kandinov, Queens College -- City University of New York, Flushing, New York

B. J. Cohen, Queens College -- City University of New York, Flushing, New York

I. A. Banerjee, Fordham University, Bronx, New York

605

MaSp2 based recombinant spider silk particles: processing of a new drug delivery vesicles

drug delivery/release

K. Kazmierska, Adam Micwiekicz University, Poznan, Poland

E. Felcyn, Greater Poland Cancer Centre, Poznan, Poland

A. Florczak, Adam Mickiewicz University, Poznan, Poland

M. Nowacka, Poznan University of Technology, Poznan, Poland

A. Mackiewicz, Poznan University of Medical Sciences, Poznan, Poland

H. Dams-Kozlowska, Greater Poland Cancer Centre, Poznan, Poland

606

Smart Transdermal Vaccine Delivery Systems Using Hyaluronic Acid Derivatives

drug delivery/release

K. Kim, Massachusetts General Hospital, Cambridge, MA

H. Kim, Pohang University of Science and Technology, Pohang, Republic of Korea

S. Yun, Massachusetts General Hospital, Cambridge, Massachusetts

S. Hahn, Pohang University of Science and Technology, Pohang, Republic of Korea

607

Heteromultivalent Ligand Modification to Enhance Specific Bioactivity of Vascular Nanomedicine Platforms

drug delivery/release; nanomedicine; platelet

L. L. Tian, Case Western Reserve University, Cleveland, OH

C. Modery, Case Western University Reserve, Cleveland, Ohio

G. Kaur, Case Western Reserve University, Cleveland, Ohio

V. Pan, Case Western Reserve University, Cleveland, Ohio

T. Wong, Case Western Reserve University, Cleveland, Ohio

M. Ravikumar, Case Western Reserve University, Cleveland, Ohio

A. Sen Gupta, Case Western Reserve University, Cleveland, Ohio

608

Surface Hybridization of Macrophages with Dendrimer via Copper-Free Click Chemistry

drug delivery/release; surface modification; tumor

L. Xu, Virginia Commonwealth University, RICHMOND, VA

609

Correlating Akt Signaling Molecule Activation to Cytocompatibility of Photoinitiators

cell culture; drug delivery/release; polymerization

L. Xu, Virginia Commonwealth University, RICHMOND, VA

610

Doped Hallyosite Nanotubes as a Drug Delivery Tool for Anti-Cancer Treatment

drug delivery/release

L. Sun, Louisiana Tech University, Ruston, LA

D. Mills, Louisiana Tech University, Ruston, Louisiana

611

Drug delivery system by micro-encapsulation of a radio-protective inclusion complex

biodegradation; drug delivery/release

L. A. Heinrich, Sr., marcotech oHG, Muenster, Germany

B. Pajaziti, Jr., Westphalian Wilhelms University Muenster, Muenster, Germany

R. Roziev, Sr., medbiopharm Ltd., Obninsk, Kaluga Region, Russian Federation

612

Effectiveness of Anti-biofilm Agents against Staphylococcus aureus biofilms

antimicrobial; drug delivery/release; infection

M. Brown, University of Kentucky, Lexington, KY

G. Huerta, University of Kentucky, Lexington, Kentucky

T. Fields, University of Kentucky, Lexington, Kentucky

R. Peyyala, University of Kentucky, Lexington, Kentucky

T. Milbrandt, University of Kentucky, Lexington, Kentucky

T. Dziubla, University of Kentucky, Lexington, Kentucky

D. Puleo, University of Kentucky, Lexington, Kentucky

613

Drug-Eluting Microarrays

adhesion; biosensors/biochips; drug delivery/release

M. R. Carstens, University of Florida, Gainesville, FL

B. G. Keselowsky, University of Florida, Gainesville, Florida

614

Controlled Release of Antimicrobial Surrogate Can Be Imaged Over 7 Days In Vivo.

animal model; antimicrobial; infection

M. Giers, Arizona State University, Tempe, AZ

615

Soybean based Absorbable Polymers for Cancer Prevention

polymer

N. Srivastava, Bezwada Biomedical, LLC, Hillsborough, NJ

616

In Situ Forming Drug Delivery Scaffold for Treating Avascular Necrosis of the Femoral Head

biodegradation; drug delivery/release; sustained release

P. Fisher, University of Kentucky, Lexington, KY

D. A. Puleo, University of Kentucky, Lexington, Kentucky

J. Z. Hilt, University of Kentucky, Lexington, Kentucky

T. A. Milbrandt, University of Kentucky, Lexington, Kentucky

617

Structural Analysis of Unimer Nanoparticles Composed of Hydrophobized Poly(amino acid)s and Their Potential Application as Drug Carriers

graft/copolymer

P. Piyapakorn, Graduate School of Engineering, Osaka University, Japan, Osaka, Japan

T. Akagi, Graduate School of Engineering, Osaka University, Osaka, Japan

M. Akashi, Graduate School of Engineering, Osaka University, Osaka, Japan

618

Combinatorial Cationic Lipid-like Nanoparticles for Efficient Intracellular Cytotoxic Protein Delivery

drug delivery/release; gene therapy/gene delivery; nanomedicine

Q. Xu, Tufts University, Medford, MA

619

Resorbable Temperature-Responsive Hydrogels Are Biocompatible Controlled Release Vehicles

animal model; antimicrobial; bioresorbable

R. McLemore, Banner Good Samaritan Medical Center, Phoenix, AZ

620

Acid-responsive micelle-forming polymers as new anticancer theraperutics

drug delivery/release; polymer; tumor

S. Park, Department of BIN Fusion Technology, Jeonju, Republic of Korea

621

Photo-cross-linkable chitosan-lactide hydrogels for growth factor delivery: Development and in vitro characterization

controlled release; drug delivery/release; growth factor

S. Kim, Stanford University, Palo Alto, CA

Y. Kang, Stanford University, Stanford, California

A. Mercado-Pagan, Stanford University, Stanford, California

Y. Yang, Stanford University, Stanford, California

622

Analysis of Molecular Weight Growth and Degradation of a Simvastatin Polymeric Prodrug

bioactive material; block copolymer; bone

T. Asafo-Adjei, University of Kentucky, Lexington, KY

D. A. Puleo, University of Kentucky, lexington, Kentucky

T. D. Dziubla, University of Kentucky, Lexington, Kentucky

623

Modulation of microRNAs for Treatment of Glioblastoma Multiforme

drug delivery/release; lipid; tumor

Y. Yin, Worcester Polytechnic Institute, Worcester, MA

D. Rassias, Worcester Polytechnic Institute, Worcester, Massachusetts

A. Jain, Worcester Polytechnic Institute, Worcester, Massachusetts

624

Co-delivery of chemo drug and siRNA using layer-by-layer nanoparticles for triple negative breast cancer treatment

drug delivery/release

Z. Deng, MIT, cambridge, MA

S. Morton, MIT, cambridge, Massachusetts

P. Hammond, MIT, cambridge, Massachusetts

625

Delivery of acetylsalicylic acid to dendritic cells using degradable micropaticles

drug delivery/release; microspheres

E. Bracho-Sanchez, University of Florida, Gainesville, FL

J. L. Lewis, Univeristy of Florida, Gainesville, Florida

B. G. Keselowsky, University of Florida, Gainesville, Florida

626

Targeting and Treating Bone Metastases Using Layer-by-Layer Functionalized Nanoparticles

bone; nanomedicine

S. Morton, Massachusetts Institute of Technology, Cambridge, MA

926

A Novel HA-based Micelle Material as a Potent Delivery System

drug delivery/release; graft/copolymer

T. Teng, Industrial Technology Research Institute, Hsinchu, Taiwan

927

Polymer Nanoparticles for Delivery of Multiple Therapeutic Agents and their Effects on Glioma Growth

drug delivery/release; nanomedicine

A. S. Ediriwickrema, Yale University, New Haven, CT

J. Zhou, Yale University, New Haven, Connecticut

M. Saltzman, Yale University, New Haven, Connecticut

928

Highly efficient siRNA delivery method by self-assembled RNA microsponges

biomaterials availability; drug delivery/release; gene therapy/gene delivery

D. Han, University of Seoul, Seoul, Republic of Korea

J. Lee, University of Seoul, Seoul, Republic of Korea

929

Characterization of UV-Responsive Expansile Nanoparticles

controlled release; drug delivery/release; nanotechnology

A. Colby, Boston University, Boston, MA

930

Cisplatin-Loaded Biodegradable Nanofiber Meshes for Treating Malignant Pleural Mesothelioma

controlled release; sustained release

J. A. Kaplan, Boston University, Newton, MA

R. Yonekura, Boston University, Boston, Massachusetts

Y. L. Colson, Brigham and Women's Hospital, Boston, Massachusetts

M. W. Grinstaff, Boston University, Boston, Massachusetts

931

Sustained Release of Functional Antibiotics From a Keratin Hydrogel

burn; controlled release; drug delivery/release

S. Tomblyn, KeraNetics, LLC, Winston-Salem, NC

H. Meng, Miami University, Oxford, Ohio

M. Ellenburg, KeraNetics, LLC, Winston-Salem, North Carolina

L. Burnett, KeraNetics, LLC, Winston-Salem, North Carolina

J. Saul, Miami University, Oxford, Ohio

932

An Implantable Intraperitoneal Drug Delivery Device for the Treatment of Advanced Ovarian Cancer

animal model; controlled release; tumor

H. Ye, Massachusetts Institute of Technology, Cambridge, MA

L. Tanenbaum, Massachusetts Institute of Technology, Cambridge, Massachusetts

M. Del Carmen, Massachusetts General Hospital, Boston, Massachusetts

M. Birrer, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts

M. J. Cima, Massachusetts Institute of Technology, Cambridge, Massachusetts

Drug Delivery for Inflammatory Diseases

627

Anti-inflammatory biocompatible dexamethasone-loaded porous microparticles for acute lung injury

biomaterials availability; drug delivery/release; inflammation

D. Jeong, Departiment of BIN Fusion Chonbuk national University ,, Jeongu, Republic of Korea

628

Hyaluronic Acid-Gold Nanoparticle-Tocilizumab Complex for the Treatment of Rheumatoid Arthritis

articular cartilage; gold; inflammation

H. Lee, POSTECH, San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk, Republic of Korea

M. Lee, POSTECH, San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk, Republic of Korea

K. Kim, POSTECH, San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk, Republic of Korea

S. Hahn, POSTECH, San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk, Republic of Korea

629

Efficacy of Three Antibiotic Loaded Polymer Coatings for Bone Screws

antimicrobial; bioresorbable; infection

Z. Hartsell, University of Memphis, Memphis, TN

A. Hoban, University of Memphis, Memphis, Tennessee

J. Bumgardner, University of Memphis, Memphis, Tennessee

H. Courtney, Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, Tennessee

M. Gosney, Smith & Nephew, Memphis, Tennessee

W. Haggard, University of Memphis, Memphis, Tennessee

933

Antimicrobial and Bioactive Composite Scaffolds for Bone Tissue Engineering

antimicrobial; bioactive material

N. HASIRCI, Middle East Technical University, ANKARA, Turkey

A. E. Aksoy, Middle East Technical University, Ankara, Turkey

V. HASIRCI, Middle East Technical University, Ankara, Turkey

Engineering Cells and Their Microenvironments

630

Directing Stem Cell Fate in 3D through Cell Inert and Adhesive Diblock Copolymer Domains

adhesion; block copolymer; stem/progenitor cells

A. J. Engler, UC San Diego, La Jolla, CA

P. Viswanathan, The University of Sheffield, Sheffield, United Kingdom (Great Britain)

S. Chirasatitsin, UC San Diego, La Jolla, California

K. Ngamkham, The University of Sheffield, Sheffield, United Kingdom (Great Britain)

G. Battaglia, The University of Sheffield, Sheffield, United Kingdom (Great Britain)

631

A Multicellular 3D Heterospheroid Liver Tumor Model for Anti-Cancer Drug Testing

biomimetic; tissue engineering; tumor

D. S. Yip, New Jersey Institute of Technology (NJIT), Newark, NJ

632

Effect of Cell Ratio on Osteoclast and Osteoblast Differentiation in a Ceramic Bone Substitute System

bone remodeling; cell culture; cell differentiation

D. T. Nguyen, Clemson University, Central, SC

K. J. L. Burg, Clemson University, Clemson, South Carolina

633

Ischemic Preconditioning to Enhance Osteogenic-Angiogenic Coupling

hydrogel

J. Blanchette, University of South Carolina, Columbia, SC

S. Sahai, University of South Carolina, Columbia, South Carolina

A. Williams, University of South Carolina, Columbia, South Carolina

M. Skiles, University of South Carolina, Columbia, South Carolina

B. Hanna, University of South Carolina, Columbia, South Carolina

634

Bioactivity of a multivalent cell membrane binder in 3D spheroid culture: effects of RGD-dendrimer conjugate on cell proliferation, expression and aggregation

bioactive material

L. Jiang, College of Engineering, Peking University, China, Beijing, China

Y. Luo, College of Engineering, Peking University, China, Beijing, China

635

Immobilization of ephrinB2 in an orientation-regulated manner on the surface of hydrogels with different elasticities

cell differentiation

M. Yamamoto, Kyoto University, Kyoto, Japan

H. Toda, Kyoto University, Kyoto, Japan

Y. Tabata, Kyoto University, Kyoto, Japan

636

Protection and Functionalization of Cell Surfaces Using Nano-Barrier Films

nanomodified surfaces

M. Matsusaki, Osaka University, Osaka, Japan

T. Yoshikai, Osaka University, Osaka, Japan

A. Matsuzawa, Mitsubishi Paper Mills Limited, Kyoto, Japan

M. Akashi, Osaka University, Osaka, Japan

637

"Co-endocytic" delivery of proteins via artificial receptor/ligand interaction on cell surface

cell therapy; controlled release; drug delivery/release

T. Mori, Kyushu University, Fukuoka, Japan

638

Time Course, Spatial Distribution, and Patterns of Spontaneous Spiking Activity of Chick Forebrain Neuronal Network Cultured on Microelectrode Array Platform

cell culture

Z. Gao, Clemson University, Clemson, SC

934

Synthetic extracellular matrix for investigating 3D vascular network formation

encapsulated cells; endothelial cells; extracellular matrix

M. P. Schwartz, University of Wisconsin-Madison, Madison, WI

J. Zhang, Morgridge Institute for Research, Madison, Wisconsin

Z. Hou, Morgridge Institute for Research, Madison, Wisconsin

D. G. Belair, University of Wisconsin-Madison, Madison, Wisconsin

A. W. Xie, University of Wisconsin-Madison, Madison, Wisconsin

M. R. Zanotelli, University of Wisconsin-Madison, Madison, Wisconsin

E. H. Nguyen, University of Wisconsin-Madison, Madison, Wisconsin

J. A. Thomson, Morgridge Institute for Research, University of Wisconsin-Madison, University of California-Santa Barbara, Madison, Wisconsin

W. L. Murphy, University of Wisconsin-Madison, Madison, Wisconsin

935

Transient Expression of Neurogenin-2 through Nanoparticles Enhances Neuronal Differentiation of Human Embryonic Stem Cell-Derived Neural Progenitors

cell differentiation; gene therapy/gene delivery

X. Li, Johns Hopkins University, Baltimore, MD

936

Directing Neural Stem Cell Recruitment: Crosstalk Signaling Between ECM and SDF-1α

extracellular matrix; regenerative medicine; stem/progenitor cells

S. Stabenfeldt, Arizona State University, Tempe, AZ

C. P. Addington, Arizona State University, Tempe, Arizona

C. Pauken, Arizona State University, Tempe, Arizona

M. R. Caplan, Arizona State University, Tempe, Arizona

Engineering Instructive Cues Biomaterials

639

Expression of Sonic Hedgehog in Non-Diabetic Wounds Treated with Poly(Methacrylic Acid-co-Methyl Methacrylate)

angiogenesis/neovascularization; bioactive material; cell-material interactions

A. Lisovsky, University of Toronto, Toronto, ON, Canada

M. V. Sefton, University of Toronto, Toronto, Ontario, Canada

640

Synergistic Effect of Silicon and Calcium Ions on Osteogenic Differentiation of Human Adipose Stem Cells

bioactive material; bone; stem/progenitor cells

A. I. Rodrigues, 3Bs Research Group, University of Minho, Portugal, Caldas das Taipas - Guimarães, Portugal

M. B. Oliveira, 3Bs Research Group, Caldas das Taipas - Guimarães, Portugal

J. F. Mano, 3Bs Research Group, Caldas das Taipas - Guimarães, Portugal

M. E. Gomes, 3Bs Research Group, Caldas das Taipas - Guimarães, Portugal

I. B. Leonor, 3Bs Research Group, Caldas das Taipas - Guimarães, Portugal

R. L. Reis, 3Bs Research Group, Caldas das Taipas - Guimarães, Portugal

641

Vesicle Trafficking as a Mechanism to Sense and Respond to Nanofiber Architecture

bone graft; cell-material interactions; fiber

A. M. Higgins, The Pennsylvania State University, University Park, PA

642

Developing Grafted Poly(γ-propargyl L-glutamate) as a Platform to Present Nano-Clustered Extracellular Cues

cell-material interactions; microstructure; polymer

C. M. Chopko, Massachusetts Institute of Technology, Cambridge, MA

J. Valdez, Massachusetts Institute of Technology, Cambridge, Massachusetts

P. Hammond, Massachusetts Institute of Technology, Cambridge, Massachusetts

L. Griffith, Massachusetts Institute of Technology, Cambridge, Massachusetts

643

Heterogeneous polymer surfaces with organized collagen layers influence preosteoblasts behavior

cell-material interactions; collagen; nanomodified surfaces

C. Dupont-Gillain, Université catholique de Louvain, Louvain-la-Neuve, Belgium

E. Zuyderhoff, Université catholique de Louvain, Louvain-la-Neuve, Belgium

644

Cellular Orientation Control Using Microcontact Printing and Mechanical Conditioning for Tissue Engineered Blood Vessels for Atherosclerosis

silicone(s) PDMS; tissue engineering; vascular graft

E. L. Lee, Boston University, Boston, MA

H. H. Bendre, Boston University, Boston, Massachusetts

J. Y. Wong, Boston University, Boston, Massachusetts

645

Combinatorial Screening of Cell Response to Surface Chemistry Gradient on a Soft Biomaterial

cell adhesion; cell-material interactions; extracellular matrix

G. Mohan, University of South Florida, Tampa, FL

N. D. Gallant, University of South Florida, Tampa, Florida

646

Development of hydrogels functionalized with cell adhesive peptide and growth factors for control of endothelial cell activities for therapeutic angiogenesis

tissue engineering

H. Shin, Hanyang University, Seoul, Republic of Korea

648

Isotropic and Directed hMSCs Migration Within a Three-dimensional, Peptide-Functionalized PEG Hydrogel

cell-material interactions; stem/progenitor cells

K. A. Kyburz, BioFrontiers Institute, University of Colorado, Boulder, CO

J. A. Young, University of Colorado, Boulder, Colorado

K. S. Anseth, BioFrontiers Institute and the Howard Hughes Medical Institute, University of Colorado, Boulder, Colorado

649

Films of varying methacrylic acid content modulate gene expression in dTHP1 and endothelial cells

cell-material interactions; polymer

L. A. Wells, University of Toronto, Toronto, ON, Canada

M. S. Valic, University of Toronto, Toronto, Ontario, Canada

M. V. Sefton, University of Toronto, Toronto, Ontario, Canada

650

Epithelial cyst phenotype is modulated by synthetic hydrogel elastic properties and adhesive ligand density

biomimetic; epithelial cells; extracellular matrix

N. O. Enemchukwu, Georgia Institute of Technology, Atlanta, GA

A. J. Garcia, Georgia Institute of Technology, Atlanta, Georgia

651

Functionalized fibronectin and RGD Titanium alloy surfaces used for Intraosseous Transcutaneous Amputation Prostheses in vitro

cell-material interactions

R. P. Dowling, University College London, Stanmore, United Kingdom (Great Britain)

C. J. Pendegrass, University College London, Stanmore, United Kingdom (Great Britain)

G. W. Blunn, University College London, Stanmore, United Kingdom (Great Britain)

652

Development of In Situ Crosslinked Electrospun Gelatin Scaffolds

bioactive material; fiber; scaffolds

R. M. Nezarati, Texas A&M University, College Station, TX

C. M. Radzicki, Texas A&M University, College Station, Texas

E. Cosgriff-Hernandez, Texas A&M University, College Station, Texas

653

An Engineered Inert Matrix for In-Vitro Maintenance of Cancer Stem Cells

hydrogel; stem/progenitor cells; tumor

S. K. Sarvestani, University of South Carolina, Columbia, SC

X. Yang, University of South Carolina, Columbia, South Carolina

E. Jabbari, University of South Carolina, Columbia, South Carolina

654

Design and Characterization of Porous MMP-sensitive Synthetic Hydrogels by Gelatin Leaching for Neovascularization Applications

angiogenesis/neovascularization; biomimetic; polymer

S. Sokic, Illinois Institute of Technology, Chicago, IL

M. Christenson, Illinois Institute of Technology, Chicago, Illinois

J. Larson, Illinois Institute of Technology, Chicago, Illinois

G. Papavasiliou, Illinois Institute of Technology, Chicago, Illinois

655

Decellularized Tissue Extracellular Matrices: a Potential Source of Biomaterials for Tissue Engineering

extracellular matrix; scaffolds; tissue engineering

Y. S. Takeda, Tufts University, Medford, MA

Q. Xu, Tufts University, Medford, Massachusetts

937

Top-Down Synthesis of Versatile Polyaspartamide Linkers for Single-step Protein Conjugation to Materials

cell adhesion; hydrogel; polymer

C. Cha, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA

J. Jeong, University of Illinois, Urbana, Illinois

H. Kong, University of Illinois, Urbana, Illinois

How Do Polymeric Implants Fail?

656

Clinical Implications of Crosslinked UHMWPE Implants with Stress Concentrations: A Retrievals Analysis

bearing surfaces; failure analysis; implant retrieval

F. Ansari, University of California, Berkeley, Berkeley, CA

E. Patten, University of California, Berkeley, Berkeley, California

J. Chang, University of California, Berkeley, Berkeley, California

S. Chou, University of California, Berkeley, Berkeley, California

A. Mehdizadeh, University of California, Berkeley, Berkeley, California

M. Kury, University of California, Berkeley, Berkeley, California

J. I. Huddleston III, Stanford University Medical Center, Redwood City, California

B. A. Jewett, Slocum Center for Orthopedics & Sports Medicine, Eugene, Oregon

D. Mickelson, University of Washington, Seattle, Washington

H. Kim, University of California, San Francisco, San Francisco, California

M. Ries, University of California, San Francisco, San Francisco, California

L. Pruitt, University of California, Berkeley, Berkeley, California

657

Bearing Surface Damage Analysis of Coupled Total Shoulder Replacement Retrievals

bearing surfaces; failure analysis; implant retrieval

L. Malito, University of California, Berkeley, Berkeley, CA

F. Ansari, University of California,  Berkeley, Berkeley, California

A. Mehdizadeh, University of California, Berkeley, Berkeley, California

J. Koller, University of California, Berkeley, Berkeley, California

S. G. Gunther, Martha Jefferson Hospital, Charlottesville, Virginia

T. Norris, San Francisco Shoulder, Elbow & Hand Clinic, San Francisco, California

M. Ries, University of California, San Francisco, San Francisco, California

L. Pruitt, University of California, Berkeley, Berkeley, California

658

Load Dependent Creep Behavior & Its Relationship to Crystallinity in Absorbable Materials

absorbable; creep

M. L. Dreher, FDA/CDRH, Silver Spring, MD

Hydrogels for Cellular Transplantation in the Central Nervous System

659

Cell-Seeded Injectable Gelatin-Hydroxyphenylpropionic Acid Hydrogel for the Regeneration of Retina

cell-material interactions; hydrogel; retina

S. Rokkappanavar, Harvard Medical School, Jamaica Plain, MA

T. Lim, Harvard-MIT Division of Health Sciences and Technology, Jamaica Plain, Massachusetts

J. Chen, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts

M. Kurisawa, Institute of Bioengineering and Nanotechnology, Singapore, Singapore

M. Spector, Harvard Medical School, Jamaica Plain, Massachusetts

Image Analysis in Implant Pathology Investigation

660

X-ray Phase Contrast Imaging of Hydrogels for Tissue Engineering

hydrogel; tissue engineering

A. A. Appel, Illinois Institute of Technology, Chicago, IL

J. C. Larson, Illinois Institute of Technology, Chicago, Illinois

A. B. Garson, III, Washington University in St. Louis, St. Louis, Missouri

B. Jiang, Illinois Institute of Technology, Chicago, Illinois

A. Zysk, Illinois Institute of Technology, Chicago, Illinois

M. O. Wang, University of Maryland, College Park, Maryland

B. B. Nguyen, University of Maryland, College Park, Maryland

E. C. Opara, Wake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina

J. Fisher, University of Maryland, College Park, Maryland

M. A. Anastasio, Washington University in St. Louis, St. Louis, Missouri

E. Brey, Illinois Institute of Technology, Chicago, Illinois

661

Long-Term Wear Analysis of Retrieved Medially-Pivoting TKA Inserts

implant retrieval; knee prosthesis; wear

W. C. Clem, Wright Medical Technology, Inc., Arlington, TN

Implant Pathology

662

Longevity of Implant-Associated Infectious Biofilms

antimicrobial; biodegradation; infection

A. M. Tatara, Rice University, Houston, TX

F. K. Kasper, Rice University, Houston, Texas

A. G. Mikos, Rice University, Houston, Texas

663

Hippocampal Neurogenesis is Down-Regulated in Animals with Small-Scale Nervous System Implants

immune response; neural prosthesis

M. B. Christensen, University of Utah, Salt Lake City, UT

B. D. Winslow, University of Utah, Salt Lake City, Utah

A. E. Higgins, University of Utah, Salt Lake City, Utah

P. A. Tresco, University of Utah, Salt Lake City, Utah

Nanomaterials

664

Intracellular Behavior of Biodegradable Dextran-graft-oligo(lactide) Nanogels Collapsing under Reductive Condition in Cytosol for Efficient Cellular Drug Delivery

biodegradation; drug delivery/release; graft/copolymer

A. Takahashi, Kansai University, Suita, Osaka, Japan

A. Kuzuya, Kansai University, Suita, Osaka, Japan

Y. OHYA, Kansai University, Suita, Osaka, Japan

665

Graphene coated substrates for cell attachment and proliferation

cell adhesion; cell-material interactions; toxicity

A. Aryaei, university of Toledo, Toledo, OH

A. Jayatissa, University of Toledo, Toledo, Ohio

M. Gautam, University of Toledo, Toledo, Ohio

A. Jayasuriya, University of Toledo, Toledo, Ohio

666

Engineering thermo-responsive nano-shells

drug delivery/release; nanotechnology; polymer

D. Cohn, The Hebrew University of Jerusalem, Jerusalem, Israel

667

Nanotechnology-derived catheters for reduced inflammation and infection

nanotechnology

L. Liu, Northeastern University, Boston, MA, Boston, MA

668

Brazilian Spider Silk Protein Masp2 Production in E.coli System with Synthetic Biology

biomolecular engineering

V. A. Michalczechen-Lacerda, University of Brasília, Brasilia, Brazil

V. A. Michalczechen-Lacerda, University of Brasília, Brasília, Brazil

O. Tokareva, Tufts University, Medford, Massachusetts

G. R. Vianna, Embrapa Genetics Resources and Biotechnology, Brasilia, Brazil

A. M. Murad, Embrapa Genetics Resources and Biotechnology, Brasilia, Brazil

D. L. Kaplan, Tufts University, Medford, Massachusetts

E. L. Rech, Embrapa Genetics Resources and Biotechnology, Brasília, Brazil

669

Preparation of Positively and Negatively Charged Nanogels Using Oligolactide-grafted Polysaccharides and Their Polyion Complex Formation

biodegradation; graft/copolymer; nanomaterials/nanophase

Y. Yano, Kansai university, Suita, Osaka, Japan

A. Furuhata, Kansai University, Suita, Japan

A. Takahashi, Kansai University, Suita, Japan

A. Kuzuya, Kansai University, Suita, Japan

Y. Ohya, Kansai University, Suita, Japan

938

The micro/nano-sized bioactive glasses and their cytological behaviours

bioactive glass; biocompatibility/hard tissue; bone marrow

C. Mao, South China University of Technology, Gainesville, FL

939

Efficacy of Novel Active Targeting Dendrimer for Paclitaxel Delivery to Breast Cancer Cells

cytotoxicity; drug delivery/release; nanotechnology

A. Satsangi, University of Texas at San Antonio, Helotes, TX

J. L. Ong, University of Texas at San Antonio, San Antonio, Texas

S. Roy, University of Texas Health Science Center at San Antonio, San Antonio, Texas

R. Vadlamudi, University of Texas Health Science Center at San Antonio, San Antonio, Texas

Nanostructured Biomaterials and Porous Scaffolds

670

Micro- to Nano-patterned Titanium Improves and Guides In Vitro Adhesion of Bone Marrow Stromal Cells

cell adhesion; surface modification; titanium (alloys)

A. F. Cipriano, University of California, Riverside, Riverside, CA

N. De Howitt, University of California, Riverside, Riverside, California

S. C. Gott, University of California, Riverside, Riverside, California

M. P. Rao, University of California, Riverside, Riverside, California

H. H. Liu, University of California, Riverside, Riverside, California

671

Posterolateral Fusion in a New Zealand White Rabbit Model

animal model; bone graft; nanomaterials/nanophase

B. M. Schlossberg, Pioneer Surgical, woburn, MA

672

Design of surfaces with mechanical nanoheterogeneities for a better control of cell-material interactions

cell-material interactions; mechanical properties; nanomodified surfaces

C. Dupont-Gillain, Université catholique de Louvain, Louvain-la-Neuve, Belgium

S. Degand, Université catholique de Louvain, Louvain-la-Neuve, Belgium

673

Synthesis and Characterization of Antiepileptic Nanomedicine for Transbuccal Delivery

biocompatibility/hard tissue; nanomedicine; scaffolds

D. C. Aduba, Jr., Virginia Commonwealth University, Richmond, VA

O. Y. Zolotarskaya, Virginia Commonwealth University, Richmond, Virginia

G. Bowlin, Virginia Commonwealth University, Richmond, Virginia

H. Yang, Virginia Commonwealth University, Richmond, Virginia

674

Microfabricated Nanoporous Gold Electrodes for Triggered Drug Release

drug delivery/release; electrodes; nanomodified surfaces

E. Seker, University of California, Davis, Davis, CA

C. A. R. Chapman, University of California, Davis, Davis, California

675

Composite Chitosan/Silk Fibroin Nanofibers for Osteogenic Differentiation of Human Mesenchymal Stem Cells

bone marrow; in vitro; nanotechnology

G. Lai, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan, Taiwan

J. Chen, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan, Taiwan

676

Injectable Nano-hybrid Scaffold for Biopharmaceuticals Delivery and Tissue Engineering

hydrogel; tissue engineering

H. Tan, Nanjing University of Science and Technology, Nanjing, China

677

Controlling the porosity of electrospun PCL scaffold by Simultaneous Salt releasing Method

polymer; porosity; scaffolds

J. Lee, Nano-Bio Regenerative Medical Institute, Hallym University, Chuncheon, Republic of Korea

678

Bioskiving: Fabrication of Tendon-derived Collagen Nerve Guidance Materials

collagen; nerve regeneration; neurons

K. A. Alberti, Tufts University, Medford, MA

Q. Xu, Tufts University, Medford, Massachusetts

679

Rosette nanotube composites for cartilage applications

cartilage; nanomedicine

L. Sun, Northeastern University, Boston, MA

680

Femtosecond Laser-Patterned Nanopore Arrays for Spatio-Temporal Control of Bioactive Molecule Release

cell-material interactions; drug delivery/release; nanomodified surfaces

L. H. Hofmeister, Vanderbilt University, Nashville, TN

A. Zachman, Vanderbilt University, Nashville, Tennessee

L. Costa, University of Tennessee Space Institute, Tullahoma, Tennessee

T. Boire, Vanderbilt, Nashville, Tennessee

W. Hofmeister, University of Tennessee Space Institute, Tullahoma, Tennessee

H. Sung, Vanderbilt University, Nashville, Tennessee

681

Poly (ethylene glycol)-poly(3,4- ethylenedioxythiophene):poly (styrenesulfonate) Hydrogel Nanofibers for Sensitive Detection of Glucose

biosensors/biochips

M. Abidian, Pennsylvania State University, University Park, PA

G. B. Kim, Pennsylvania State University, State College, Pennsylvania

682

Response of chitosan/PCL nanofibers with airway epithelial cells

biocompatibility/soft tissue; epithelial cells; nanomaterials/nanophase

N. Bhattarai, North Carolina A&T State University, Greensboro, NC

683

On the Use of Dexamethasone Loaded Liposomes to Induce the Osteogenic Differentiation of Human Mesenchymal Stem Cells

cell differentiation; drug delivery/release; stem/progenitor cells

N. S. Monteiro, 3B´s Research Group – Biomaterials, Biodegradables and Biomimetics, Guimaraes, Portugal

684

Release of Bioactive Agent from Liposomes Immobilized on Electrospun Nanofibers Targeting Tissue Engineering Applications

cell differentiation; drug delivery/release; scaffolds

N. S. Monteiro, 3B´s Research Group – Biomaterials, Biodegradables and Biomimetics, Guimaraes, Portugal

685

Directional Cell Migration Induced by Electrospun Silk Nanofibers

cell-material interactions; fiber; nanomodified surfaces

P. Uttayarat, Thailand Institute of Nuclear Technology (Public Organization), Nakornnayok, Thailand

687

Hydrogel Composites Containing Carbon Nanobrushes as an Effective Biomaterial for Tissue Regeneration

biomimetic; cell-material interactions; nanomaterials/nanophase

W. H. Marks, Harvard University, Cambridge, MA

S. C. Yang, University of Rhode Island, Kingston, Rhode Island

G. W. Dombi, University of Rhode Island, Kingston, Rhode Island

S. K. Bhatia, Harvard University, Cambridge, Massachusetts

689

Bundle Structure Gel Formation Using the Co-flow Microfluidic Device

hydrogel; polymerization; scaffolds

Y. Takahashi, The University of Tokyo., Tokyo, Japan

N. Kato, Utsunomiya University, Utsunomiya, Japan

Y. T. Matsunaga, The University of Tokyo, Tokyo, Japan

940

Structural, Mechanical and In Vitro Characterization of Plasma-Coated Electrospun Nanofiber Scaffolds for Vascular Graft Applications

polyethylene-terephthalate; surface modification; vascular graft

H. Savoji, 1- École Polytechnique de Montréal,  2- Laboratory of Endovascular Biomaterials (LBeV), Research Centre, Centre Hospitalier de l’Université de Montreal (CRCHUM), Montreal, QC, Canada

A. Hadjizadeh, École Polytechnique de Montréal, Montreal, Québec, Canada

M. Maire, Laboratory of Endovascular Biomaterials (LBeV), Research Centre, Centre Hospitalier de l’Université de Montreal (CRCHUM), Montreal, Montreal, Québec, Canada

S. Lerouge, 1- École de Technologie Supérieure,  2- Laboratory of Endovascular Biomaterials (LBeV), Research Centre, Centre Hospitalier de l’Université de Montreal (CRCHUM), Montreal, Québec, Canada

A. Ajji, École Polytechnique de Montréal, Montreal, Québec, Canada

M. R. Wertheimer, École Polytechnique de Montréal, Montreal, Québec, Canada

941

Degradation of Ultrasound Contrast Agents Embedded in a Tissue Phantom

degradation; microspheres; nanomaterials/nanophase

S. Gleeson, Case Western Reserve University, Cleveland, OH

L. Solorio, Case Western Reserve University, Cleveland, Ohio

A. A. Exner, Case Western Reserve University, Cleveland, Ohio

Ophthalmic Biomaterials

690

Ocular Biocompatibility of a SIBS-based Glaucoma Drainage Tube

biocompatibility/soft tissue; ophthalmic; polymer

Y. P. Kato, InnFocus Inc, Miami, FL

691

Surface-Modified Silicone Contact Lenses from Interfacial Design to Clinical Evaluation

ophthalmic; silicone(s) PDMS; surface modification

Z. Zhang, Semprus BioSciences, Cambridge, MA

J. Li, Semprus BioSciences, Cambridge, Massachusetts

H. Wang, Semprus BioSciences, Cambridge, Massachusetts

D. Donahue, Semprus BioSciences, Cambridge, Massachusetts

C. Loose, Semprus BioSciences, Cambridge, Massachusetts

A. Cook, Semprus BioSciences, Cambridge, Massachusetts

692

Development of a Biomimetic Vitreous Substitute

biomimetic; hydrogel; vitreous

N. Ravi, V.A. Medical Center, St. Louis, MO

P. D. Hamilton, VA Medical Center, St. Louis, Missouri

942

Poly(ethylene glycol) based Diels-Alder hydrogels for biomedical applications

hydrogel

A. Goepferich, University of Regensburg, Regensburg, Germany

Orthopaedic Biomaterials

693

Nanoclay Enriched Electrospun Polycaprolactone Scaffolds for Bone Tissue Engineering

bone; nanomaterials/nanophase; scaffolds

A. Gaharwar, Massachusetts Institute of Technology, Cambridge, MA

S. Mukundan, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

A. Patel, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

S. Mihaila, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

A. Dolatshahi-Pirouz, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

E. Karaca, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

K. Ragaranjan, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

A. Khademhosseini, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

694

Clinical Relevance of ISO 18192-1 Spinal Disc Wear Parameters to the PCM Cervical Disc System

polyethylene (UHMWPE); spinal implant; wear

A. W. L. Turner, NuVasive, Inc., San Diego, CA

695

Fretting Corrosion Analysis of Ti-Mo-Zr-Fe (TMZF) and Gas Atomized Dispersion Strengthened Co-Cr-Mo (GADS) Alloys Under Shot Peened,  and Shot Peened, Cleaned and Passive Conditions

biomechanics; corrosion; fretting

A. J. Ferrel, Syracuse University, Syracuse, NY

696

Surface Cross-linking of Vitamin E Blended UHMWPE by Low Energy Irradiation

orthopedic; osteolysis; polyethylene (UHMWPE)

A. Neils, Massachusetts General Hospital, Boston, MA

J. Ward, Massachusetts General Hospital, Boston, Massachusetts

B. Doshi, Massachusetts General Hospital, Boston, Massachusetts

E. Oral, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

697

The initial concentration of vitamin E in irradiated UHMWPE affects vitamin E grafting

orthopedic; polyethylene (UHMWPE)

A. Neils, Massachusetts General Hospital, Boston, MA

E. Oral, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

698

Fabrication of Crosslinked Carboxymethylchitosan Microspheres and Their Incorporation Into Composite Scaffolds for Enhanced Bone Regeneration

bone; sustained release; tissue engineering

B. Reves, University of Memphis, Germantown, TN

J. A. Jennings, University of Memphis, Memphis, Tennessee

J. D. Bumgardner, University of Memphis, Memphis, Tennessee

W. O. Haggard, University of Memphis, Memphis, Tennessee

699

Strength and Friction Characteristics of a Porous Structured Titanium Biomaterial

orthopedic; porous coated

B. S. Mitchell, Pipeline Orthopedics, cedar knolls, NJ

D. F. Swarts, Pipeline Orthopedics, cedar knolls, New Jersey

700

Diffusion of Vitamin E in Radiation Cross-linked UHMWPE using Homogenization under Pressure

orthopedic; polyethylene (UHMWPE)

B. Doshi, Massachusetts General Hospital, Boston, MA

E. Oral, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

701

Bioactivity of Amorphous Bioactive Glass and Glass-Ceramic in Simulated Body Fluid

bioactive glass; bioactive material

C. S. Lewis, Bio2 Technologies, Woburn, MA

J. Krevolin, Bio2 Technologies, Woburn, Massachusetts

702

Novel Porous Titanium Implants Demonstrate Bone Ingrowth In A Rabbit Model

C. Ngo, Stryker Orthopaedics, Mahwah, NJ

R. Zhang, Stryker Orthopedics, Mahwah, New Jersey

M. Poggie, Stryker Orthopaedics, Mahwah, New Jersey

G. Kulesha, Stryker Orthopaedics, Mahwah, New Jersey

J. Muth, Stryker Orthopaedics, Mahwah, New Jersey

C. Aponte, Stryker Orthopaedics, Mahwah, New Jersey

S. Coyle, Stryker Orthopaedics, Mahwah, New Jersey

N. Dong, Stryker Orthopaedics, Mahwah, New Jersey

703

Surface Crosslinking of Vitamin E Blended UHMWPE via Spatial Extraction of Vitamin E Through High Temperature Processing

polyethylene (UHMWPE)

C. Gupta, Massachusetts General Hospital, Boston, MA

E. Oral, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

704

Poly(vinyl alcohol)-poly(2-acrylamido-2-methyl-1-propane sulfonic acid) hydrogels as a synthetic cartilage material

cartilage; hydrogel

C. Serrano, Massachusetts General Hospital, Boston, MA

H. Bodugoz-Senturk, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

705

Physical and Mechanical Characteristics of a Porous Structured Titanium Biomaterial

implant design; porous coated; titanium (alloys)

D. F. Swarts, Pipeline Orthopedics, Cedar Knolls, NJ

706

Osseointegration Effect of BMP-2 on Dental Implants: A 3-6 Week In Vivo Study

calcium phosphate(s); cell-material interactions; histomorphometry

D. Y. Yoo, New York University College of Dentistry, New York, NY

C. Marin, Universidade Federal de Santa Catarina, Florianopolis, Brazil

R. Jimbo, Malmo University, Malmo, Sweden

R. Anchieta, New York University College of Dentistry, New York, New York

L. Machado, New York University College of Dentistry, New York, New York

F. Guastaldi, New York University College of Dentistry, New York, New York

N. Tovar, New York University College of Dentistry, New York, New York

P. G. Coelho, New York University College of Dentistry, New York, New York

707

Vitamin-E highly crosslinked UHMWPE wear particles induce less osteolysis compared to virgin UHMWPE in murine calvarial bone model

cartilage; polyethylene (UHMWPE)

D. Bichara, Massachusetts General Hospital, Boston, MA

E. Malchau, Massachusetts General Hospital, Boston, Massachusetts

N. Sillesen Hylleholt, Massachusetts General Hospital, Boston, Massachusetts

S. Cakmak, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

708

Bond Quality and Corrosion Properties of Titanium Foam on Cobalt Chrome Substrates

arthroplasty; corrosion; porous coated

D. Scholvin, Wright Medical Technology, Inc., Arlington, TN

J. P. Moseley, Wright Medical Technology, Inc., Arlington, Tennessee

D. Linton, Wright Medical Technology, Inc., Arlington, Tennessee

709

Effect of Irradiation on the Strength and Lubricity of PVA-PAA Hydrogels for Cartilage Repair

cartilage

D. Ling, Massachusetts General Hospital, Boston, MA

H. Bodugoz-Senturk, Massachusetts General Hospital, Boston, Massachusetts

H. Kluk, Masachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

710

A New Technique for Surface Cross-linked UHMWPE by Diffusion of Peroxides

orthopedic; polyethylene (UHMWPE)

E. Oral, Massachusetts General Hospital, Boston, MA

R. Gul, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

711

Oxidation Resistant Peroxide Crosslinked UHMWPE

orthopedic; polyethylene (UHMWPE)

E. Oral, Massachusetts General Hospital, Boston, MA

R. Gul, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

712

Coefficient of Friction for Porous Metal Structures Against Cortical Bone

bone; orthopedic

G. Gupta, Biomet, Warsaw, IN

K. McKlain, Biomet, Warsaw, Indiana

713

Novel Microwave Assisted Route for Preparing Monetite Bone Cement with No Heat Generation

biocompatibility/hard tissue; calcium phosphate(s); ceramic

H. Zhou, The University of Toledo, Toledo, OH

S. B. Bhaduri, The University of Toledo, Toledo, Ohio

T. J. F. Luchini, The University of Toledo, Toledo, Ohio

A. K. Agawal, The University of Toledo, Toledo, Ohio

V. K. Goel, The University of Toledo, Toledo, Ohio

714

Fabrication of Customized Porous Hydroxyapatite (HA) implants for Orthopaedic Application

bone graft; hydroxy apatite; orthopedic

H. Jung, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea

T. Jang, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea

M. Kang, Department of Materials Science and Engineering, Seoul, Republic of Korea

H. Kim, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea

Y. Koh, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea

Y. Estrin, cDepartment of Materials Engineering, Monash Univers, Seoul, Australia

715

Impact Strength Correlates with Fatigue Strength of Irradiated Vitamin E/UHMWPE Blends

orthopedic; polyethylene (UHMWPE)

J. Ward, Massachusetts General Hospital, Boston, MA

B. Doshi, Massachusetts General Hospital, Boston, Massachusetts

E. Oral, Massachusetts General Hospital, Boston, Massachusetts

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

716

Magnesium ions facilitate integrin alpha-2 and alpha-3-mediated proliferation and partially promotes differentiation in hBMSCs

biodegradation; bone; osteogenesis

K. Lee, Asan Medical Center, Seoul, Republic of Korea

717

Engineering the Rate of Degradation of Polyester Scaffolds for Bone Tissue Engineering

biocompatibility/hard tissue; biodegradation; polymer

K. N. Cicotte, University of New Mexico, Albuquerque, NM

S. M. Dirk, Sandia National Laboratories, Albuquerque, New Mexico

E. L. Hedberg-Dirk, University of New Mexico, Albuquerque, New Mexico

718

A Co-Polymer of Chitosan and Dextran Coating on Ti6Al4V for Orthopedic Applications

cell-material interactions; coating(s); degradation

L. Actis, The University of Texas at San Antonio, San Antonio, TX

A. Srinivasan, The University of Texas at San Antonio, San Antonio, Texas

A. Ramasubramanian, The University of Texas at San Antonio, San Antonio, Texas

J. L. Ong, The University of Texas at San Antonio, San Antonio, Texas

719

A Clinically Relevant Oxidation Model for UHMWPE and its Comparison to Retrievals

orthopedic; polyethylene (UHMWPE)

M. Fung, Massachusetts General Hospital, Boston, MA

O. Muratoglu, Massachusetts General Hospital, Boston, Massachusetts

S. Rowell, Massachusetts General Hospital, Boston, Massachusetts

A. Neils, Massachusetts General Hospital, Boston, Massachusetts

E. Oral, Massachusetts General Hospital, Boston, Massachusetts

720

Bioactive PEEK

bioactive material; coating(s); failure analysis

S. Ajami, UCL, University College London, STANMORE, MIDDLESEX, United Kingdom (Great Britain)

M. Coathup, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

A. McCabe, Accentus, Oxfordshire, United Kingdom (Great Britain)

J. Shawcross, Accentus, Oxfordshire, United Kingdom (Great Britain)

P. Agg, Accentus, Oxfordshire, United Kingdom (Great Britain)

G. Blunn, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

721

Injectable, Bioactive Two-solution Bone Cements (η-TSBC) with Strontium Substituted Hydroxyapatite Microspheres

bioactive material; bone cement (= PMMA, acrylic); hydroxy apatite

S. Jariwala, Syracuse University, Syracuse, NY

J. Hasenwinkel, Syracuse University, Syracuse, New York

722

The Effect of Silica-substitution, Sintering and Particle Size on Bone Healing of Apatite Granules

calcium phosphate(s)

S. Woods, DePuy Synthes, West Chester, PA

A. Petticoffer, DePuy Synthes, West Chester, Pennsylvania

D. Arens, AO Research Institute, Davos, Switzerland

723

Wear Rates of Ultra High Molecular Weight Polyethylene (UHMWPE) uncorrelated to Contact Area

wear

S. A. Woods, DePuy Orthopaedics, Warsaw, IN

724

Comparative Handling, Intrusion and Antibiotic Elution Characteristics of a New, High Viscosity Bone Cement

bone cement (= PMMA, acrylic); fixation; joint replacement

S. He, Stryker Co, Mahwah, NJ

S. He, Stryker Co, Mahwah, New Jersey

H. Mulvihill, Stryker Co, Limerick, Ireland

Y. Bogatch, Stryker Co, Mahwah, New Jersey

E. O'Grandy, Stykrer Co, Limerick, Ireland

D. McQueen, Kansas Orthopaedic Center, Wichita, Kansas

725

Cell-mediated degradable hydrogels tailored to adult cells for cartilage tissue engineering

articular cartilage; enzyme(s); hydrogel

S. C. Skaalure, University of Colorado, Boulder, CO

S. J. Bryant, University of Colorado, Boulder, Colorado

726

A Comparison of Small Punch Results on Aged Highly Crosslinked UHMWPE

oxidation; polyethylene (UHMWPE); polymer

S. Spiegelberg, Cambridge Polymer Group, Boston, MA

C. Segura, Cambridge Polymer Group, Boston, Massachusetts

M. Peiserich, Zimmer, Inc., Warsaw, Indiana

A. Rufner, Zimmer, Inc., Warsaw, Indiana

727

Radiation-Induced Radicals in Polyaryletheretherketone (PEEK)

total joint replacement

T. Riahinasab, University of Memphis, Memphis, TN

B. Walters, University of Memphis, Memphis, Tennessee

M. S. Jahan, University of Memphis, Memphis, Tennessee

728

Real-time Monitoring of Hardening of Nanosilica Sol containing DCPA Cements in an ESEM

calcium phosphate(s); composite/hard tissue; test method

H. Zhou, The University of Toledo, Toledo, OH

H. Zhou, The University of Toledo, Toledo, Ohio

S. Bhaduri, The University of Toledo, Toledo, Ohio

T. J. F. Luchini, The university of toledo, Findlay, Ohio

729

Effect of UHMWPE Patellar Component Thickness on Quadriceps Tendon Force Following Total Knee Arthroplasty

biomechanics; computer modeling/simulation; total joint replacement

X. Xie, Clemson University, Clemson, SC

J. DesJardins, Clemson University, Clemson, South Carolina

H. Yao, Clemson University, Charleston, South Carolina

L. Thompson, Clemson University, Clemson, South Carolina

F. Voss, University of South Carolina, School of Medicine, Columbia, South Carolina

M. LaBerge, Clemson University, Clemson, South Carolina

730

Porous polyurethane scaffold for facilitating healing in critical sized bone defect

bone; bone graft; osteogenesis

Y. Lui, The University of Hong Kong, Hong Kong, Hong Kong

W. Ip, The University of Hong Kong, Hong Kong, Hong Kong

731

Reducing Cytotoxicity of Injectable Poly(propylene-co-caprolactone) Copolymers for Bone Tissue Engineering

cytotoxicity; polymer

Z. Fang, Mayo Clinic, Rochester, MN

943

Comparison of the Fixation Strength of PEEK and Composite Knotless Instability Anchors

implant design

M. Hawkins, Stryker Orthopaedics, Mahwah, NJ

J. Spalazzi, Stryker Orthopaedics, Mahwah, New Jersey

944

Enhanced Bioactivity of PEEK by Accelerated Neutral Atom Beam Technique

bioactive material; nanomodified surfaces; PEEK

M. H. Maxwell, Exogenesis Corporation, Billerica, MA

S. Kirkpatrick, Exogenesis Corporation, Billerica, Massachusetts

R. Svrluga, Exogenesis Corporation, Billerica, Massachusetts

J. Khoury, Exogenesis Corporation, Billerica, Massachusetts

945

A Biomechanical Study to Compare an All-Suture Anchor to a Composite Suture Anchor in Sheep Cadaver Humeri

biomechanics; orthopedic; suture

J. N. Bair, IMDS Discovery Research, Logan, UT

R. E. Olsen, IMDS Discovery Research, Logan, Utah

J. Pugsley, IMDS Discovery Research, Logan, Utah

K. Pilgeram, Stryker Orthopaedics, San Jose, California

946

Biomechanical Testing of Soft Tissue Allografts Sterilized Using Two Different Methods

ligament(s); mechanical properties; sterilization

M. Hawkins, Stryker Joint Preservation, Mahwah, NJ

C. Kevin, University of Colorado - Denver, Aurora, Colorado

T. Baldini, University of Colorado - Denver, Aurora, Colorado

E. McCarty, University of Colorado - Denver, Aurora, Colorado

947

Comparison of Silicated–Apatite and β-TCP Granules in a Critical Size Bone Defect Model

animal model; calcium phosphate(s); histomorphometry

A. C. Petticoffer, Depuy Synthes, West Chester, PA

S. A. Woods, Depuy Synthes, West Chester, Pennsylvania

M. Fulmer, Depuy Synthes, West Chester, Pennsylvania

R. Harten, Depuy Synthes, West Chester, Pennsylvania

948

Cationic, Multifunctional Dendrimers for Treatment of Osteoarthritis

articular cartilage; polymer; surface modification

B. G. Cooper, Boston University, Boston, MA

M. W. Grinstaff, Boston University, Boston, Massachusetts

C. Ghobril, Boston University, Boston, Massachusetts

949

Contrast Enhanced Computed Tomography of Equine Joint Cartilage Demonstrates Consistent Imaging Relationships Across Joint Surfaces

articular cartilage; cartilage; extracellular matrix

R. Stewart, Boston University, Allston, MA

B. Nelson, Colorado State University, Fort Collins, Colorado

H. Lusic, Boston University, Boston, Massachusetts

B. Snyder, Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, Massachusetts

L. Goodrich, Colorado State University, Fort Collins, Colorado

M. Grinstaff, Boston University, Boston, Massachusetts

950

Engineering a Muscle Mimetic Extracellular Matrix Biomaterial

extracellular matrix; muscle

S. Hurd, University of Arkansas, Fayetteville, AR

B. Kasukonis, University of Arkansas, Fayetteville, Arkansas

K. Cherry, University of Arkansas, Fayetteville, Arkansas

S. Ahmadi, University of Arkansas for Medical Sciences, Little Rock, Arkansas

J. Wolchok, University of Arkansas, Fayetteville, Arkansas

951

Fabrication and Characterization of Poly(para-phenylene) for use as a Porous Scaffold Biomaterial

polymer; porosity; spinal implant

C. P. Frick, University of Wyoming, Laramie, WY

A. L. DiRienzo, University of Wyoming, Laramie, Wyoming

C. M. Yakacki, University of Colorado at Denver, Denver, Colorado

D. L. Safranski, MedShape Solutions, Inc., Atlanta, Georgia

952

Degradation and characterization of porous constructs for craniofacial space maintenance and antibiotic delivery

biodegradation; bone

A. Henslee, Rice University, Houston, TX

Patterning Microenvironments for Tissue Engineering and Morphogenesis

732

Biomechanics of Cell Sheets Based Arterial Tissue using a Novel Force Sensor

biomechanics; tissue engineering

D. E. Backman, Boston University, Boston, MA

J. Y. Wong, Boston University, Boston, Massachusetts

733

Orthogonal Photo-reactive Hydrogel of Tunable Stiffness for In Vitro Guided Neurite Growth

nerve regeneration; scaffolds; tissue engineering

E. L. Horn-Ranney, Tulane University, New Orleans, LA

P. Khoshakhlagh, Tulane University, New Orleans, Louisiana

M. J. Moore, Tulane University, New Orleans, Louisiana

734

Two-Dimensional Micropatterns of Self-Assembled Poly(N-isopropylacrylamide) Microgels for Adhesion, Alignment, and Temperature-induced Detachment of NIH 3T3 Fibroblast Cells

cell-material interactions; microstructure; tissue engineering

H. Tsai, University of Rochester, Rochester, NY

K. Vats, University of Rochester, Rochester, New York

M. Z. Yates, University of Rochester, Rochester, New York

D. S. W. Benoit, University of Rochester, Rochester, New York

735

Bioengineering a tendon-like substitute: adult stem cell behavior in aligned fibrous scaffolds and stimulating culturing environments

cell differentiation; stem/progenitor cells; tissue engineering

M. T. Rodrigues, 3B's Research Group - University of Minho, Caldelas das Taipas - Guimarães, Portugal

736

A Contour-Based Approach Enables Individual Cell Identification for Cell-Material Analyses

cell-material interactions; surface analysis; tissue engineering

M. E. Brasch, Syracuse University, Syracuse, NY

R. M. Baker, Syracuse University, Syracuse, New York

L. Manning, Syracuse University, Syracuse, New York

J. H. Henderson, Syracuse University, Syracuse, New York

737

Biomimetic substrate-dependent myogenic commitment of iPSC-derived cells

stem/progenitor cells

N. Hwang, Seoul National University, Seoul, Republic of Korea

E. Lee, Seoul National University, Seoul, Republic of Korea

953

Cell Motility and Persistence Controlled by Topography of Cell Culture Substrates

cell-material interactions

W. Tong, City University of Hong Kong, Hong Kong, Hong Kong

Q. Tand, City University of Hong Kong, Hong Kong, Hong Kong

S. Peng, City University of Hong Kong, Hong kong, Hong Kong

S. Pang, City University of Hong Kong, Hong Kong, Hong Kong

Y. Lam, City University of Hong Kong, Hong Kong, Hong Kong

954

Selective cell patterning on photoactive electrospun meshes

cell adhesion; hydrophilic; hydrophobic

J. S. Hersey, Boston University, Boston, MA

M. W. Grinstaff, Boston University, Boston, Massachusetts

955

Effects of Blocking Cell-Cell and Cell-Matrix Interactions on Cardiac Cell Mechanical Properties

atomic force microscopy; cell-cell interactions; extracellular matrix

A. Desai, Clemson University, Clemson, SC

S. Deitch, Clemson University, Clemson, South Carolina

D. Dean, Clemson University, Clemson, South Carolina

Physical Parameters in the Design of Drug Delivery Systems

738

Injectable Multiblock P(PF-co-CL) Copolymer and Dual Drug Delivery for Treatment of Bone Defects

bone; drug delivery/release; orthopedic

M. Dadsetan, Mayo Clinic, Rochester, MN

956

Injectable and Degradable Sulfated Hyaluronic Acid Hydrogels for Sustained Protein Delivery

biodegradation; controlled release; hydrogel

V. Chuo, University of Pennsylvania, Philadelphia, PA

B. Purcell, University of Pennsylvania, Philadelphia, Pennsylvania

S. M. Dorsey, University of Pennsylvania, Philadelphia, Pennsylvania

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

Proteins and Cells at Interfaces

739

Quantification of the Influence of Protein-Protein Interactions on Adsorbed Protein Structure and Bioactivity

enzyme(s); protein adsorption; protein conformation

A. A. Thyparambil, Clemson University, Clemson, SC

Y. Wei, Clemson University, Clemson, South Carolina

R. A. Latour, Clemson University, Clemson, South Carolina

740

Collection of prostaglandin E2 and leukotriene B4 from implanted microdialysis probes

foreign body reactions (response); wound healing

A. Diaz-Perez, University of Arkansas, Fayetteville, AR

741

Directing Macrophage Polarization with Microdialysis Probe Implants: Perfusion Fluid and IL-4 Effects

cytokines; foreign body reactions (response); wound healing

G. Bajpai, University of Arkansas, Fayetteville, AR

742

Interaction Forces Related to Protein Adsorption on Polymer Brush Surfaces

atomic force microscopy; protein adsorption; surface analysis

S. Sakata, The University of Tokyo, Tokyo, Japan

Y. Inoue, The University of Tokyo, Tokyo, Japan

K. Ishihara, The University of Tokyo, Tokyo, Japan

743

Recovering functionalities of deficient mucus with a polyethylene glycol-lectin conjugate

bacterial adherence; biomolecular engineering; epithelial cells

T. Crouzier, Massachusetts Institute of Technology, Cambridge, MA

K. Ribbeck, MIT, Cambridge, Massachusetts

744

Development of Tuned Interfacial Force Field Parameters in CHARMM for the Accurate Molecular Dynamics Simulation of Peptide Adsorption on Biomaterial Surfaces

adsorption; molecular modeling; protein adsorption

T. Abramyan, Clemson University, Clemson, SC

J. A. Snyder, Clemson University, Clemson, South Carolina

J. A. Yancey, Clemson University, Clemson, South Carolina

S. J. Stuart, Clemson University, Clemson, South Carolina

R. A. Latour, Clemson University, Clemson, South Carolina

Role of Biological Factors in Osteoconduction and Bone Engineering

745

Synergistic effect of sustained release growth factors from PLGA microspheres and dynamic bioreactor flow on hMSC osteogenic differentiation in alginate scaffolds

growth factor; microspheres; sustained release

B. B. Nguyen, University of Maryland, College Park, MD

G. Della Porta, Università di Salerno, Fisciano, SA, Italy

E. Reverchon, Università di Salerno, Fisciano (Sa), Italy

J. P. Fisher, University of Maryland, College Park, Maryland

746

Surface modified PLLA as drug delivery scaffold for bone regeneration

bioactive material; osteogenesis; polymer

M. Bosetti, Università del Piemonte Orientale "A. Avogadro", Novara, Italy

747

Influence of Bone Morphogenetic Protein-7 Encapsulated and Coated Chitosan Microparticles on Osteoblasts Proliferation and Differentiation

controlled release; growth factor

V. P. R. Mantripragada, The University of Toledo, Toledo, OH

Stem Cell-Biomaterial Interactions

748

Stable Feeder- and Xeno-free Surfaces for Long-term Growth of Undifferentiated Human Embryonic Stem Cells

fibronectin/vitronectin; polymerization; stem/progenitor cells

A. R. DiIenno, Massachusetts Institute of Technology, Cambridge, MA

A. M. Coclite, Massachusetts Institute of Technology, Cambridge, Massachusetts

J. R. Millman, Massachusetts Institute of Technology, Cambridge, Massachusetts

J. Tan, Massachusetts Institute of Technology, Cambridge, Massachusetts

C. K. Colton, Massachusetts Institute of Technology, Cambridge, Massachusetts

K. K. Gleason, Massachusetts Institute of Technology, Cambridge, Massachusetts

749

Elucidating the role of integrin α5 in mediating the therapeutic potency of circulating angiogenic cells cultured on collagen matrix

angiogenesis/neovascularization; integrins; matrix

B. Vulesevic, University of Ottawa Heart Institute, Ottawa, ON, Canada

B. McNeill, University of Ottawa Heart Institute, Ottawa, Ontario, Canada

M. Ruel, University of Ottawa Heart Institute, Ottawa, Ontario, Canada

E. J. Suuronen, University of Ottawa Heart Institute, Ottawa, Ontario, Canada

750

Functional roles of microRNA 489 and 148b in hMSCs osteogenesis depend on microenvironment elasticity.

cell differentiation; cell-material interactions; extracellular matrix

. Yang, University of Colorado, Boulder, Boulder, CO

K. S. Anseth, University of Colorado, Boulder, Boulder, Colorado

751

Differentiation of Human Bone Marrow Mesenchymal Stem Cells on Decellularized Extracellular Matrix Materials

cell differentiation; extracellular matrix; stem/progenitor cells

D. M. Hoganson, Washington University in St. Louis, St. Louis, MO

A. M. Meppelink, Massachusetts General Hospital, Boston, Massachusetts

C. J. Hinkel, Washington University in St. Louis, St. Louis, Missouri

S. M. Goldman, DSM Biomedical, Exton, Pennsylvania

S. Liu, DSM Biomedical, Exton, Pennsylvania

J. P. Gaut, Washington University in St. Louis, St. Louis, Missouri

J. P. Vacanti, Massachusetts General Hospital, Boston, Massachusetts

752

Biphasic Peptide Amphiphile Nanomatrix Scaffold for Enhanced Osteogenic Response

bone; nanomedicine; tissue engineering

H. Jun, University of Alabama at Birmingham, Birmingham, AL

J. Vines, University of Alabama at Birmingham, Birmingham, Alabama

D. Patel, University of Alabama at Birmingham, Birmingham, Alabama

J. Anderson, University of Alabama at Birmingham, Birmingham,, Alabama

S. Gilbert, University of Alabama at Birmingham, Birmingham,, Alabama

D. Lim, University of Alabama at Birmingham, Birmingham,, Alabama

753

The Effect of Fiber Size on the Neuronal Differentiation of Mouse Embryonic Stem Cells

cell differentiation; cell-material interactions; tissue engineering

J. M. Holzwarth, University of Michigan, Ann Arbor, MI

754

The Potential of Tissue Engineering in Maxillofacial Reconstruction Following Oral Cancer Treatment

bone graft; cell differentiation; maxillofacial

J. Shaul, Clemson University, Central, SC

755

Novel Sugar-Glass Nanoparticles system for Biomolecules Stabilization and Delivery in Tissue Engineering Applications

diabetes; nanomaterials/nanophase; nanotechnology

j. Giri, Parffenbarg Research Center,, Gaithersburg, MD

756

Modified PEGDA Hydrogels to Promote Mesenchymal Stem Cell Adhesion In Vitro

cell adhesion; stem/progenitor cells; surface modification

K. M. Ferlin, University of Maryland, College Park, MD

M. E. Prendergast, University of Maryland, College Park, Maryland

D. S. Kaplan, Food and Drug Administration, Silver Spring, Maryland

J. P. Fisher, University of Maryland, College Park, Maryland

757

Effect of Titanium Nanotopography on Mesenchymal Stem Cell Fate

cell differentiation; stem/progenitor cells; titanium (alloys)

M. M. Beloti, School of Dentistry of Ribeirao Preto - University of Sao Paulo, Ribeirao Preto, Brazil

R. B. Kato, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil

F. S. de Oliveira, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil

M. Q. Hassan, School of Dentistry, University of Alabama at Birmingham, Birmingham, Alabama

P. T. de Oliveira, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil

A. L. Rosa, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil

758

Differentiation of Adipose Derived Stem Cells on Nanofibrous Collagen and Elastin Matrices

cell differentiation; cell-material interactions; stem/progenitor cells

M. J. Springer, University of Florida, Gainesville, FL

J. Allen, University of Florida, Gainesville, Florida

759

Multifunctional Scaffold for the Delivery of Neural Stem Cells to Promote Regeneration after Traumatic Brain Injury

cell-material interactions; stem/progenitor cells; tissue engineering

N. B. Skop, University of Medicine and Dentistry of New Jersey and New Jersey Institute of Technology, Newark, NJ

C. H. Cho, New Jersey Institute of Technology, Newark, New Jersey

S. W. Levison, University of Medicine and Dentistry of New Jersey, Newark, New Jersey

760

Modulation of Cell Behaviour using Self–Assembled Binary Colloidal Crystals

cell culture; cell-material interactions; nanomodified surfaces

P. Wang, Industrial Research Institute Swinburne (IRIS), Swinburne University of Technology, Hawthorn VIC, Australia, Melbourne, Australia

761

Viability and Function of Induced Pluripotent Stem (IPS) Cell-Derived Hepatocytes on Bioprinted Gelatin Scaffolds

cell-material interactions; stem/progenitor cells; tissue engineering

R. N. Shah, Northwestern University, Chicago, IL

A. Rutz, Northwestern University, Chicago, Illinois

A. Jakus, Northwestern University, Chicago, Illinois

K. Chien, Northwestern University, Chicago, Illinois

762

The Effects of Mechanical Stimulation on Controlling and Maintaining Marrow Stromal Cell Differentiation into Vascular Smooth Muscle Cells

bone marrow; stem/progenitor cells; strain

R. Yao, Boston University, Watertown, MA

763

Patterned Polyethylene glycol Coatings for Peptide Presentation and Cellular Adhesion

cell-material interactions

S. K. Schmitt, University of Wisconsin - Madison, Madison, WI

D. J. Ciancio, University of Wisconsin-Madison, Madison, Wisconsin

W. L. Murphy, University of Wisconsin - Madison, Madison, Wisconsin

P. Gopalan, University of Wisconsin - Madison, Madsion, Wisconsin

764

Functional analysis of zinc finger and BTB domain containing 16 (ZBTB16) during osteoblastic differentiation of periodontal ligament-derived human multipotent mesenchymal stromal cells

osteogenesis

S. Onizuka, Section of Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan

765

Engineered Collagen-Glycosaminoglycan Scaffold Arrays for Understanding Regulators of MSC Fate

cell-material interactions; stem/progenitor cells

S. R. Caliari, University of Illinois at Urbana-Champaign, Urbana, IL

766

Effect of Surface Chemistry on Stem Cell Response in 2-D vs. 3-D Cell Culture Niches

bone; cell differentiation; cell-material interactions

S. Sarkar, National Institute of Standards and Technology, Gaithersburg, MD

C. G. Simon, Jr., National Institute of Standards and Technology, Gaithersburg, Maryland

R. I. Lock, National Institute of Standards and Technology, Gaithersburg, Maryland

J. P. Dunkers, National Institute of Standards and Technology, Gaithersburg, Maryland

767

Supplemental Magnesium Ions Altered Human Embryonic Stem Cell Morphology while Retaining Pluripotency

metal ions; scaffolds; stem/progenitor cells

T. Nguyen, University of California, Riverside, Moreno Valley, CA

C. Liew, University of California, Riverside, Riverside, California

H. Liu, University of California, Riverside, Riverside, California

768

Stem Cell-Based Meniscus Tissue Engineering Using a Hydrogel Form of Decellularized Matrix

extracellular matrix; meniscus; stem/progenitor cells

X. Yuan, Columbia University, New York, NY

D. E. Arkonac, Columbia University, New York, New York

G. Vunjak-Novakovic, Columbia University, New York, New York

769

Formation of Embryoid Bodies with Controlled Sizes and Maintained Pluripotency in Three-Dimensional Alginate Inverse Opal Scaffolds

cell therapy; cell-material interactions; regenerative medicine

Y. Zhang, Georgia Institute of Technology, Atlanta, GA

Y. Xia, Georgia Institute of Technology, Atlanta, Georgia

957

GHK-Modified Alginate Hydrogels Enhance VEGF Secretion by Mesenchymal Stem Cells

angiogenesis/neovascularization; hydrogel; stem/progenitor cells

K. Leach, UC Davis, Davis, CA

M. Hughbanks, UC Davis, Davis, California

Surface Characterization and Modification

770

Surface Characterization of Nano-Features Induced by a Low Temperature Oxidation Method

dental/craniofacial material; nanomaterials/nanophase; nanomodified surfaces

A. Cheng, Georgia Institute of Technology, Atlanta, GA

771

Enzymatic pH Control enables Spatially Controlled CaP Deposition onto Micropatterned Surfaces

calcium phosphate(s)

A. W. G. Nijhuis, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands

772

An Approach for Assessing Scaffold Hydrophobicity

cell-material interactions; contact lens; controlled release

D. Munoz-Pinto, Rensselaer Polytechnic Institute, Troy, NY

B. Grigoryan, Texas A&M University, College Station, Texas

M. Grunlan, Texas A&M University, College Station, Texas

M. S. Hahn, Rensselaer Polytechnic Institute, Troy, New York

773

Surface Functionalization of Cobalt-Chromium Alloy Using Phosphoric and Phosphonoacetic Acids

atomic force microscopy; cobalt-chromium (alloys); FTIR

E. Thiruppathi, The University of South Dakota, Sioux Falls, SD

J. Peacock, The University of South Dakota, Sioux Falls, South Dakota

G. Mani, The University of South Dakota, Sioux Falls, South Dakota

774

Surface roughness properties of a micro-textured carbide-coated CoCrMo implant alloy during wear

surface characterization; total joint replacement; wear

G. Ettienne-Modeste, University of Maryland, Baltimore County, Nottingham, MD

775

Surface modification of poly(D,L-lactic acid) scaffolds for orthopedic applications: a non-destructive route via diazonium chemistry

polymer; surface characterization; surface modification

H. Mahjoubi, McGill University, Montreal, QC, Canada

M. Cerruti, McGill University, Montreal, Québec, Canada

776

Nano-structured surface modification on Ti alloy by electron cyclotron resonance plasma oxidation

calcification; surface modification

H. Masumoto, Tohoku University, Sendai, Japan

777

Inorganic/Organic Coating Layer to Induce Apatite Formation in DPBS

bioactive material

I. Lee, Yonsei  University, Seoul, Republic of Korea

778

Preparation and Characterization of Functional Polypyrrole Particles

polymer

J. Mao, Centre de recherché du CHU de Québec, Université Laval, Québec City, QC, Canada

779

Versatile surface modification of biomaterials using biocompatible and photoreactive phospholipid polymers

surface modification

K. Fukazawa, The University of Tokyo, Tokyo, Japan

780

Flexible Polyetherimide-Silica Hybrid Xerogel Coating on Magnesium

biodegradation; coating(s); polymer

M. Kang, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea

781

QCM-D as an useful tool for the combined immobilization of cell adhesion peptide and growth factor on biomaterial surfaces.

adhesion; immobilization; surface characterization

P. Thalla, École de technologie supérieure (ÉTS), Montreal, QC, Canada

782

Tricalcium phosphate embedded poly(vinylidene fluoride) coating on magnesium for biomedical applications

biocompatibility/hard tissue; coating(s); stents

S. Kim, WCU Hybrid Materials Program, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea., Seoul, Republic of Korea

H. Park, WCU Hybrid Materials Program, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Seoul, Republic of Korea

H. Kim, WCU Hybrid Materials Program, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea., Seoul, Republic of Korea

784

Evaluating the Level of Adhesion and Optimizing Thermal Bonding between Nitinol Wire and Thermoplastic Polymer Films.

adhesion

S. Navada, College of Textiles, North Carolina State University, Raleigh, NC

785

Regulating Smooth Muscle Cells on Poly(ethylene glycol)-grafted Poly(epsilon-caprolactone) Networks

cell-material interactions; polymer; surface modification

S. Wang, The University of Tennessee, Knoxville, TN

X. Liu, The University of Tennessee, Knoxville, Tennessee

786

Versatile surface functionalization of inorganic materials with cyclic phosphoesters

nanomodified surfaces; protein adsorption; surface characterization

Y. Iwasaki, Kansai University, Osaka, Japan

Y. Yamamoto, Kansai University, Osaka, Japan

T. Shimomura, Kansai University, Osaka, Japan

787

Facile method of preparing of temperature-responsive cell culture surface by using photoinitiator immobilized polystyrene surfaces

cell culture; cell-material interactions; tissue culture

Y. AKIYAMA, Tokyo Women's Medical University, Tokyo, Japan

788

Shear Stress-dependent Cell Detachment from Temperature-responsive Cell Culture Surfaces in Microfluidic Device

cell adhesion; cell-material interactions; surface characterization

Z. Tang, Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women’s Medical University, Tokyo, Japan

Z. Tang, Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women’s Medical University, Tokyo, Japan

Y. Akiyama, Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women’s Medical University, Tokyo, Japan

K. Itoga, Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women’s Medical University, Tokyo, Japan

J. Kobayashi, Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women’s Medical University, Tokyo, Japan

T. Okano, Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women’s Medical University, Tokyo, Japan

958

Microporous Ti implant compact coated with hydroxyapatite produced by electro-discharge-sintering and electrostatic-spray-deposition

surface modification

Y. Jo, Sejong University, Seoul, Republic of Korea

W. Lee, Sejong University, Seoul, Republic of Korea

S. Cheon, Sejong University, Seoul, Republic of Korea

Y. Jo, Sejong University, Seoul, Republic of Korea

Y. Kim, wonkwang health science university, Jeonbuk, Republic of Korea

959

Surface Micromechanical Testing Methods for Contact Lenses: Indentation, Friction and Dehydration

contact lens; hydrogel; surface characterization

J. L. Gilbert, Syracuse University, Syracuse, NY

E. A. Lewis, Syracuse University, Syracuse, New York

Surface Functionalization of Nanomaterials for Therapy and Diagnostics

960

Angiotensin II-functionalized Quantum Dot Interactions with Cells

nanobiology; nanomedicine

A. Goepferich, University of Regensburg, Regensburg, Germany

961

Modifying the Surface Chemistry of pH-Responsive Expansile Nanoparticles for Altered Circulation, Targeting and Efficacy Towards Cancer

drug delivery/release; nanomedicine; surface modification

M. Stolzoff, Boston University, Boston, MA

A. H. Colby, Boston University, Boston, Massachusetts

C. Ghobril, Boston University, Boston, Massachusetts

J. S. Hersey, Boston University, Boston, Massachusetts

Y. L. Colson, Brigham and Women's Hospital, Boston, Massachusetts

T. M. Porter, Boston University, Boston, Massachusetts

M. W. Grinstaff, Boston University, Boston, Massachusetts

Surface Modification of Biomaterials for Local Therapy and Diagnostics

789

Targeted Inhibition of HIV-1 Utilizing a Bioengineered Nanofibrous Polyester Material

infection; surface modification

J. Araya, Northeastern University, Ashland, MA

L. Fitzgerald, Biosurfaces, Inc., Ashland, Massachusetts

T. Phaneuf, Biosurfaces, Inc., Ashland, Massachusetts

S. Pathan, Biosurfaces, Inc., Ashland, Massachusetts

D. Nelson, Biosurfaces, Inc., Ashland, Massachusetts

D. Thoresen, Saint Michael's College, Ashland, Massachusetts

M. Bide, University of Rhode Island, Ashland, Massachusetts

T. Phaneuf, Biosurfaces, Inc., Ashland, Massachusetts

M. Phaneuf, Biosurfaces, Inc., Ashland, Massachusetts

790

Functionalized polyanhydride nanoparticles preserve protein stability and activate antigen presenting cells

drug delivery/release; nanomaterials/nanophase; surface modification

J. E. Vela Ramirez, Iowa State University, Ames, IA

R. Roychoudhury, Indiana University, Bloomington, Indiana

H. Habte, Iowa State University, Ames, Iowa

M. Cho, Iowa State University, Ames, Iowa

N. Pohl, Indiana University, Bloomington, Indiana

M. Wannemuehler, Iowa State University, Ames, Iowa

B. Narasimhan, Iowa State University, Ames, Iowa

791

Functionalization of Pentablock Copolymers with Pathogen-Mimicking Sugars for Targeted Delivery

block copolymer; immune response; surface modification

J. Adams, Iowa State University, Ames, IA

S. Mallapragada, Iowa State University, Ames, Iowa

N. Pohl, Indiana University, Bloomington, Indiana

M. Goswami, Iowa State University, Ames, Iowa

792

Selective Deposition of Conductive Polymer Films Using Agarose Stamps

hydrogel; microstructure; polymer

E. E. Richards, The Pennsylvania State University, University Park, PA

N. Madduri, The Pennsylvania State University, University Park, Pennsylvania

M. R. Abidian, The Pennsylvania State University, University Park, Pennsylvania

S. Majd, The Pennsylvania State University, University Park, Pennsylvania

793

Mechanical Properties of Triclosan Containing Sol-gel Thin Films on Titanium Alloy

coating(s); mechanical properties; stress cracking

H. Qu, University of Pennsylvania, Philadelphia, PA

794

A Strongly Adherent, Biocompatible, Efficacious Antimicrobial Coating for Orthopedic Implants

antimicrobial; orthopedic; sustained release

M. A. Schallenberger, Bacterin International, Inc., Belgrade, MT

T. R. Meyer, Bacterin International, Inc., Belgrade, Montana

H. M. Lovick, Bacterin International, Inc., Belgrade, Montana

795

Lower critical solution temperature of copolymers of N-vinyl-2-caprolactam and its derivative: effects of pH and polymer compositions

polymer

S. Tang, University of Tennessee, Knoxville, Knoxville, TN

Y. Cao, University of Tennessee, Knoxville, Tennessee

S. Goddard, University of Tennessee, Knoxville, Knoxville, Tennessee

W. He, University of Tennessee, Knoxville, Knoxville, Tennessee

Surface Modification Strategies for Antimicrobial Medical Devices

797

A Thermodynamic Approach to Engineering Antifouling Surfaces

bacterial adherence; cell adhesion; cell-material interactions

J. T. Decker, University of Florida, Gainesville, FL

C. M. Kirschner, University of Florida, Boulder, Colorado

C. Long, University of Florida, Gainesville, Florida

J. Finlay, University of Birmingham, Birmingham, United Kingdom (Great Britain)

M. Callow, University of Birmingham, Birmingham, United Kingdom (Great Britain)

J. Callow, University of Birmingham, Birmingham, United Kingdom (Great Britain)

A. Brennan, University of Florida, Gainesville, Florida

798

Fabricating antibacterial paper towels through the use of selenium nanoparticles

antimicrobial

Q. Wang, Northeastern Univeristy, Boston, MA

Surgical Meshes - Recent Development and Application

799

A Preliminary Study on Effects of Cyclic Loading and In Vitro Degradation on Mesh Porosity

fatigue; morphology; porosity

M. Deng, Johnson & Johnson Global Surgery Group, Somerville, NJ

V. Zhou, Johnson & Johnson, Somerville, New Jersey

E. Vailhe, Johnson & Johnson, Somerville, New Jersey

J. Flint, Johnson & Johnson, Somerville, New Jersey

M. Deng, Johnson & Johnson, Somerville, New Jersey

Sustainable Approaches to Degredable Drug Delivery Materials

800

Hyperbranched Polyester Hydrogels with Controlled Drug Release and Cell Adhesion Properties

bioactive material; drug delivery/release; nanomaterials/nanophase

A. K. Gaharwar, Massachusetts Institute of Technology, Cambridge, MA

H. Zhang, Brigham and Women’s Hospital, Harvard Medical School,, Cambridge, Massachusetts

A. Patel, Brigham and Women’s Hospital, Harvard Medical School,, Cambridge, Massachusetts

S. Mihaila, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

G. Iviglia, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

S. Mukundan, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

H. Bae, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

H. Yang, University of Science and Technology, Anhui, China, China

A. Khademhosseini, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, Massachusetts

801

An injectable nanodelivery system for prolonged release of the local anesthetic lidocaine

suture; wound dressings

I. K. Yazdi, The Methodist Hospital Research Institute, Houston, TX

S. Khaled, The Methodist Hospital Research Institute, Houston, Texas

J. Van Eps, The Methodist Hospital, Houston, Texas

J. Fernandez-Moure, The Methodist Hospital, Houston, Texas

N. Taghipour, The Methodist Hospital Research Institute, Houston, Texas

J. Martinez, The Methodist Hospital Research Institute, Houston, Texas

S. Haddix, The Methodist Hospital Research Institute, Houston, Texas

E. Tasciotti, The Methodist Hospital Research Institute, Houston, Texas

802

Controlled sequential release of multi-agents from layer-by-layer films for surface delivery applications

controlled release; nanoassembled devices; orthopedic

J. Min, Massachusetts Institute of Technology, Cambridge, MA

The Role of Antioxidants in Biomaterials

803

Electron Beam Warm Irradiation Improves Oxidative Resistance and Grafting of Blended Vitamin E Polyethylene

FTIR; polyethylene (UHMWPE); radiation

D. Pletcher, Zimmer, Inc., Warsaw, IN

M. Guo, Zimmer, Inc., Warsaw, Indiana

A. Rufner, Zimmer, Inc., Warsaw, Indiana

804

Effects of Natural Antioxidants on Polyethylene Radicals in UHMWPE

polyethylene (UHMWPE)

M. S. Jahan, University of Memphis, Memphis, TN

B. Walters, University of Memphis, Memphis, Tennessee

A. Ali, AgResearch Ltd., Christchurch, New Zealand

A. Ghosh, AgResearch Ltd., Christchurch, New Zealand

805

Effect of Vitamin C on the Growth of Endothelial Cells for Stent and Vascular Graft Applications

cardiovascular; endothelialization; in vitro

S. Kakade, The University of South Dakota, Sioux Falls, SD

G. Mani, The University of South Dakota, Sioux Falls, South Dakota

962

Evaluation of Oxidation Induction Time as a Tool for Characterization of AO Content

polyethylene (UHMWPE); polymer

M. A. Ross, DePuy Synthes Joint Reconstruction, Warsaw, IN

V. S. Narayan, DePuy Synthes Joint Reconstruction, Warsaw, Indiana

Tissue Engineering

806

Enzymatic Treatment of Minced Porcine Cartilage Improves Cellular Outgrowth and GAG Production in 3D in vitro Cultures

articular cartilage; cartilage; enzyme(s)

A. J. McNally, Exactech, Inc., Gainesville, FL

C. Chapman, Exactech, Inc., Gainesville, Florida

K. Sly, Exactech, Inc., Gainesville, Florida

S. Lin, Exactech, Inc., Gainesville, Florida

807

The Effect of Adding a Hydrogel Porogen into a Poly(lactic-co-glycolic acid) Scaffold

biodegradation; mechanical properties

A. Clark, University of Kentucky, Lexington, KY

808

Electrospinning of Chitosan and its Correlation with Degree of Deacetylation and Rheological Property

adhesion; extracellular matrix; wound healing

A. Nandgaonkar, North Carolina State University, Raleigh, NC

W. Krause, North Carolina State University, Raleigh, North Carolina

809

Enhanced cell proliferation on controlled pore size of chitosan nanofibers mat

wound dressings

B. Gu, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea

S. Park, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea

M. Kim, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea

C. Kim, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea

811

Surface Modification of Poly(ε-caprolactone) Scaffolds Fabricated via Selective Laser Sintering for Cartilage Regeneration in Craniofacial Surgery

cartilage; surface modification; tissue engineering

C. Chen, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan 33302, Taiwan, ROC, Tao-Yuan, Taiwan

812

Liquified Capsules Encapsulating Microparticles to Provide Cell Adhesion Sites Enhance Cellular Functions

encapsulated cells; microspheres; tissue engineering

C. R. Correia, 3B's Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal

R. L. Reis, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal

J. F. Mano, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal

813

Poly(butylene succinate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) blend nanofibers for skin tissue engineering

artificial skin; biocompatibility/soft tissue; cell-material interactions

D. Sundaramurthi, SASTRA University, Thanjavur, India

U. Krishnan, SASTRA University, Thanjavur, India

S. Sethuraman, SASTRA University, Thanjavur, India

814

Gelatin-based Hydrogels as Potential Cellular Delivery Systems for Cardiac Tissue Engineering

cardiovascular; cell therapy; encapsulated cells

G. Camci-Unal, Harvard Medical School, Cambridge, MA

N. Alemdar, Harvard Medical School, Cambridge, Massachusetts

A. Khademhosseini, Harvard Medical School, Cambridge, Massachusetts

815

Fabrication of Anisotropic Cell Sheets for Designing Well-organized Myotube Assembly

cell-material interactions; regenerative medicine; tissue engineering

H. Takahashi, Tokyo Women's Medical University, Tokyo, Japan

816

Co-culture of Human Gingival Fibroblasts and Vascular Endothelial Cells in a Perfused Degradable/Polar/Hydrophobic/Ionic Polyurethane (D-PHI)

endothelial cells; fibroblasts; tissue engineering

J. W. C. Cheung, University of Toronto, Toronto, ON, Canada

C. A. G. McCulloch, University of Toronto, Toronto, Ontario, Canada

J. Santerre, University of Toronto, Toronto, Ontario, Canada

817

Development of Interconnected PolyHIPEs for Injectable Bone Grafts

bone graft; scaffolds; tissue engineering

J. L. Robinson, Texas A&M University, College Station, TX

R. S. Moglia, Texas A&M University, College Station, Texas

M. C. Stuebben, Texas A&M University, College Station, Texas

M. A. P. McEnery, Texas A&M University, College Station, Texas

E. Cosgriff-Hernandez, Texas A&M University, College Station, Texas

818

Effects of Low Oxygen Tension during Expansion on Chondrogenic Potential of Osteoarthritis Chondrocytes

articular cartilage; cell culture; tissue engineering

J. Wang, Syracuse Biomaterials Institute and the Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY

K. Davis, Syracuse Biomaterials Institute and the Department of Biomedical and Chemical Engineering  Syracuse University, Syracuse, New York

J. Henderson, Syracuse Biomaterials Institute and the Department of Biomedical and Chemical Engineering  Syracuse University, Syracuse, New York

819

Tyrosine-Derived Polycarbonates to Treat a Rabbit Critical-Sized Segmental Bone Defect

bone graft; tissue engineering

J. Kim, Hongik University, Sejong, Republic of Korea

820

Nanocomposite Bone Scaffolds Based on Biodegradable Polymers and Hydroxyapatite

bone; bone remodeling

M. Dadsetan, Mayo Clinic, College of Medicine, Rochester MN; Paracelsus Medical University, Salzburg, Austria, Rochester, MN

821

Decellularized Human Vocal Fold as a Scaffold for Laryngeal Tissue Engineering

extracellular matrix; scaffolds; tissue engineering

J. R. Tse, University of California, Los Angeles, Cerritos, CA

J. L. Long, University of California, Los Angeles, Los Angeles, California

822

Tissue Engineered Model of the Inner Neural Retina

regenerative medicine; retina; scaffolds

K. E. Kador, Bascom Palmer Eye Institute,University of Miami Miller School of Medicine, Miami, FL

P. Venugopalan, Bascom Palmer Eye Institute,University of Miami Miller School of Medicine, Miami, Florida

R. B. Montero, University of Miami, Coral Gables, Florida

J. Hertz, Bascom Palmer Eye Institute,University of Miami Miller School of Medicine, Miami, Florida

E. Lavik, Case Western Reserve University, Cleveland, Ohio

F. Andreopoulos, University of Miami, Coral Gables, Florida

J. L. Goldberg, Bascom Palmer Eye Institute,University of Miami Miller School of Medicine, Miami, Florida

823

hMSC and Fibroblast Dispersion Cultures in Chitosan-based Injectable Hydrogels for Cartilage Regeneration

cartilage; cell differentiation; hydrogel

K. J. Walker, Oklahoma State University, Stillwater, OK

S. V. Madihally, Oklahoma State University, Stillwater, Oklahoma

824

In Situ Crosslinkable Gelatin Hydrogel for Ex Vivo Organ Culture of Cardiac Tissue

biomaterials availability; tissue engineering

K. Park, Ajou University, Suwon, Republic of Korea

K. Park, Ajou University, Suwon, Republic of Korea

Y. Lee, Ajou University, Suwon, Republic of Korea

J. Son, Ajou University, Suwon, Republic of Korea

Y. Yang, Inje University School of Medicine, Busan, Republic of Korea

825

Preparation and characterization of soft tissue-polymer complex for percutaneous device

composite/soft tissue; dermal substitutes; polymerization

K. Nam, Tokyo Medical and Dental University, Tokyo, Japan

R. Matsushima, Tokyo Medical and Dental University, Tokyo, Japan

Y. Shimatsu, Tokyo Medical and Dental University, Tokyo, Japan

T. Kimura, Tokyo Medical and Dental University, Tokyo, Japan

T. Fujisato, Osaka Institute of Technology, Osaka, Japan

A. Kishida, Tokyo Medical and Dental University, Tokyo, Japan

826

Smooth Muscle Cell Migration in 3D Biomimetic Poly(ethylene glycol) Hydrogels

biodegradation; biomimetic; cell adhesion

L. Lin, Case Western Reserve University, Cleveland Heights, OH

J. Zhu, Case Western Reserve University, Cleveland, Ohio

K. Kottke-Marchant, Cleveland Clicnic, Cleveland, Ohio

R. Marchant, Case Western Reserve University, Cleveland, Ohio

827

Responses of Vascular Endothelial Cells to Photo-embossed Topography on Polymer Films and Fibers

adhesion; cell-material interactions; endothelial cells

L. Qiu, Institute of Bioengineering, Queen Mary, University of London, London, United Kingdom, London, United Kingdom (Great Britain)

828

Pre-vascularized Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels improve Skin wound healing

cell adhesion; stem/progenitor cells; tissue engineering

M. T. Cerqueira, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

L. da Silva, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

T. Santos, 3B's Research Group, University of MInho, Caldas das Taipas, Guimarães, Portugal

R. Pirraco, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

A. Martins, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

V. Correlo, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

A. P. Marques, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

R. L. Reis, 3B's Research Group, University of Minho, Caldas das Taipas, Guimarães, Portugal

829

A new technique for Development of perfusable multilayered blood vessel-like structures on Microfluidic Chip

vascular

M. Hasan, Harvard Medical School, Cambridge, MA

G. Jeong, Harvard Medical School, Cambridge, Massachusetts

830

Processing and Storage Effects on Poly(ethylene glycol) Hydrogel Mechanical Properties and Bioactivity

cell adhesion; hydrogel; mechanical properties

P. Luong, Texas A&M University, College Station, TX

M. Browning, Texas A&M University, College Station, Texas

R. Bixler, Texas A&M University, College Station, Texas

E. Cosgriff-Hernandez, Texas A&M University, College Station, Texas

831

Designing Degradable Microporous Bacterial Cellulose Scaffolds and its Biomimetic Composites for Bone and Cartilage Tissue Engineering

biomimetic; bioresorbable; stem/progenitor cells

P. Favi, University of Tennessee - Knoxville, Knoxville, TN

832

Structural and Compositional Changes of Porcine Articular Cartilage After Partial Enzymatic Digestion

cartilage; extracellular matrix; microstructure

P. Lee, Exactech Taiwan, Hsinchu, Taiwan

C. Chen, Exactech Taiwan, Hsinchu, Taiwan

K. Sly, Exactech Inc., Gainesville, Florida

S. Lin, Exactech Inc., Gainesville, Florida

833

Development of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) nanofibrous scaffold for esophageal tissue engineering

regenerative medicine; scaffolds; tissue engineering

P. Kuppan, SASTRA University, Thanjavur, India

S. Sethuraman, SASTRA University, Thanjavur, India

U. Krishnan, SASTRA University, Thanjavur, India

834

Mechanical properties of stem cells from different sources during vascular smooth muscle cell differentiation

bone marrow; stem/progenitor cells; vascular

R. Chen, Clemson University, Clemson, SC

D. Dean, Clemson University, Clemson, South Carolina

835

Combination Delivery of Small RNAs Enhances Muscle Regeneration

gene therapy/gene delivery; muscle; regenerative medicine

S. Lee, Wake Forest School of Medicine, Winston-Salem, NC

N. Kim, Wake Forest School of Medicine, Winston-Salem, North Carolina

836

Host Stem Cell Mobilization for In Situ Muscle Tissue Regeneration

muscle; tissue engineering

S. Lee, Wake Forest School of Medicine, Winston-Salem, NC

837

Biomechanics and Bioresorbable Material Study toward Pelvic Organ Prolapse Corrective Mesh Design

biomechanics; biomimetic; scaffolds

S. Aghyarian, Department of Chemistry and The Alan G. MacDiarmid NanoTech Institute, The University of Texas at Dallas, Richardson, TX

C. Manz, Department of Materials Science and Engineering, The University of Texas at Dallas, Richardson, Texas

A. Pereira, Department of Chemistry and The Alan G. MacDiarmid NanoTech Institute, The University of Texas at Dallas, Richardson, Texas

N. Mammoottil, Department of Chemistry and The Alan G. MacDiarmid NanoTech Institute, The University of Texas at Dallas, Richardsoon, Texas

C. Watson, Department of Chemistry and The Alan G. MacDiarmid NanoTech Institute, The University of Texas at Dallas, Rchardson, Texas

B. Lund, Department of Chemistry and The Alan G. MacDiarmid NanoTech Institute, The University of Texas at Dallas, Richardson, Texas

P. Zimmern, Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas

R. Eberhart, Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas

H. Tibbals, Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas

W. Voit, Department of Materials Science and Engineering, The University of Texas at Dallas; Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 4Department of Mechanical Engineering, The University of Texas at Dallas, Richardson, Texas

D. Smith, Department of Chemistry and The Alan G. MacDiarmid NanoTech Institute, The University of Texas at Dallas; Department of Materials Science and Engineering, The University of Texas at Dallas, Richardson, Texas

838

Structural Deformation Studies of Scaffolds and Method for Non-Invasively Monitoring Tissue Growth

mechanical properties; permeability; scaffolds

S. Madihally, Oklahoma State University, Stillwater, OK

J. Podichetty Thribhuvan, Oklahoma State University, Stillwater, Oklahoma

839

Enhancing Segmental Defect Regeneration through a Thrombopoietic Agent

bone

T. G. Chu, Indiana University School of Dentistry, Indianapolis, IN

840

Preparation and Characterization of Porcine Esophageal Extracellular Matrix

biocompatibility/soft tissue; extracellular matrix

T. Keane, University of Pittsburgh, Pittsburgh, PA

R. Londono, University of Pittsburgh, Piitsburgh, Pennsylvania

R. Carey, University of Pennsylvania, Pittsburgh, Pennsylvania

J. Reing, University of Pittsburgh, Pittsburgh, Pennsylvania

S. F. Badylak, University of Pittsburgh, Pittsburgh, Pennsylvania

841

Platelet-Derived Growth Factor Stimulated Migration of Bone Marrow Mesenchymal Stem Cells into an Injectable Gelatin-Hydroxyphenylpropionic Acid Hydrogel

hydrogel; regenerative medicine; tissue engineering

W. Niu, VA Boston Healthcare System, Brigham and Women's Hospital, Boston, MA

842

Conductive Fabrics for Electrically Stimulated Cell Culture

cell-material interactions; electrical stimulation; surface modification

Y. Wang, Laval University, Quebec, QC, Canada

M. Rouabhia, Laval University, Québec, Québec, Canada

Z. Zhang, Laval University, Québec, Québec, Canada

843

Rapid Formation of Engineered Microvasculatures Using Microfluidic Techniques

tissue engineering; vascular

Y. T. Matsunaga, The University of Tokyo, Tokyo, Japan

N. Brandenberg, The University of Tokyo, Tokyo, Japan

I. Matsuda, The University of Tokyo, Tokyo, Japan

M. Umezu, Waseda University, Tokyo, Japan

Y. Okubo, The University of Tokyo, Tokyo, Japan

844

In Situ Forming Gelatin-Based Bioadhesive and Sprayable Hydrogels for Skin Regeneration

biomaterials availability; tissue engineering; wound healing

Y. Lee, Ajou University, Suwon, Republic of Korea

J. Bae, Ajou University, Suwon, Republic of Korea

K. Park, Ajou University, Suwon, Republic of Korea

845

Minimally Invasive Spine Fracture Risk Prediction Based on QCT and Image Analysis

orthopedic; polymer; spinal implant

Z. Fang, Mayo Clinic, Rochester, MN

963

Small diameter acellular vascular grafts with integrin a4b1 positive cell-caputuring surface

blood-material interface; tissue engineering; vascular graft

T. YAMAOKA, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

S. Somekawa, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

N. Kobayashi, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

Y. Hirano, Kansai University, Suita, Japan

N. Mihashi, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

T. Sakuma, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

T. Moritan, Suzuka University of Medical Science, SuzukaSuzuka, Japan

Y. Kimura, Kyoto Institute of Technology, Kyoto, Japan

T. Fujisato, Osaka Institute of Technology, Osaka, Japan

A. Mahara, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

Translational Research in Nano-biomaterials

846

Histologic and Histomorphometric Analysis of Two Graft Materials in a Non-instrumented Canine Interspinous Spinal Fusion Model

bone graft; calcium phosphate(s); nanomodified surfaces

A. S. Ismailoglu, NuVasive Inc., San Diego, CA

H. Yuan, University of Twente, Enschede, Netherlands

F. Vizesi, NuVasive Inc., San Diego, California

X. Luo, University of Twente, Enschede, Netherlands

J. de Bruijn, University of Twente, Enschede, Netherlands

E. Erbe, NuVasive Inc., San Diego, California

847

Characterization of Porcine Vascular Tissue and Gold Nanoparticles as a Vascular Graft Material

nanomodified surfaces; vascular graft

A. M. Ostdiek, University of Missouri, Columbia, MO

S. Grant, University of Missouri, Columbia, Missouri

848

Carbon Nanotube-Polyimide Composite Microneedles for Rapid Transdermal Drug Delivery

drug delivery/release; nanomaterials/nanophase

B. J. Lyon, California Institute of Technology, Pasadena, CA

A. Aria, California Institute of Technology, Pasadena, California

M. Gharib, California Institute of Technology, Pasadena, California

849

Nanosilver Surfaces for Improved Understanding of Biocompatibility and Antibacterial Efficacy of Medical Device Coatings

antimicrobial; nanomodified surfaces; toxicity

E. M. Sussman, U.S. Food and Drug Administration, Silver Spring, MD

B. J. Casey, U.S. Food and Drug Administration, Silver Spring, Maryland

J. Zheng, U.S. Food and Drug Administration, Silver Spring, Maryland

B. J. Dair, U.S. Food and Drug Administration, Silver Spring, Maryland

D. V. Patwardhan, U.S. Food and Drug Administration, Silver Spring, Maryland

850

Microwave Assisted Synthesis of Alkaline Earth Phosphates Nanospheres

bioactive material; ceramic; nanomaterials/nanophase

H. Zhou, The University of Toledo, Toledo, OH

S. B. Bhaduri, The University of Toledo, Toledo, Ohio

T. J. F. Luchini, The University of Toledo, Toledo, Ohio

851

Microwave Assisted Alkaline Earth Phosphate Biomimetic Coating Deposition on Implants

biomimetic; ceramic; coating(s)

H. Zhou, The University of Toledo, Toledo, OH

V. K. Goel, University of Toledo, Toledo, Ohio

S. B. Bhaduri, The University of Toledo, Toledo, Ohio

852

Auricular Reconstruction with a Novel Nanocomposite Scaffold

cell-material interactions; nanomaterials/nanophase; scaffolds

L. Nayyer, Univeresity College London (UCL), London, United Kingdom (Great Britain)

853

Fabrication of Novel Polylactic Acid/Amorphous Magnesium Phosphate Bionanocomposite Fibers for Tissue Engineering Applications via Electrospinning

polymer; scaffolds; tissue engineering

M. Nabiyouni, University of Toledo, Toledo, OH

854

Regulation of Human Tendon Fibroblast Response by Fiber Diameter of Electrospun Polymer Scaffolds

cell-material interactions; connective tissue; scaffolds

N. M. Lee, Columbia University, New York, NY

C. Erisken, Columbia University, New York, New York

W. N. Levine, Columbia University, New York, New York

H. H. Lu, Columbia University, New York, New York

855

Nano-grafts for Anterior Cruciate Ligament Reconstruction

gold; hydroxy apatite; nanomaterials/nanophase

S. E. Smith, University of Missouri, Columbia, MO

S. Grant, University of Missouri, Columbia, Missouri

R. White, University of Missouri, Columbia, Missouri

Tribocorrosion of Metallic Biomaterials

856

Factors Affecting the Performance of Metal Components in Artificial Hips

arthroplasty; cobalt-chromium (alloys); wear

O. Vesnovsky, U.S. Food and Drug Administration, Silver Spring, MD

N. P. Anderson, U.S. Food and Drug Administration, Silver Spring, Maryland

M. A. Di Prima, U.S. Food and Drug Administration, Silver Spring, Maryland

C. A. Engh, Jr., Anderson Orthopaedic Institute, Alexandria, Virginia

L. W. Grossman, U.S. Food and Drug Administration, Silver Spring, Maryland

R. Hopper, Anderson Orthopaedic Institute, Alexandria, Virginia

B. Stephen, U.S. Food and Drug Administration, Silver Spring, Maryland

L. Topoleski, University of Maryland Baltimore County, Baltimore, Maryland

Wound Dressings That Do More Than Covering the Wounds

857

Development of Vancomycin-Linked Poly(β-amino ester) Hydrogels

antimicrobial; controlled release; hydrogel

A. Vasilakes, University of Kentucky, Lexington, KY

D. Puleo, University of Kentucky, Lexington, Kentucky

J. Hilt, University of Kentucky, Lexington, Kentucky

T. Dziubla, University of Kentucky, Lexington, Kentucky

858

Dynamic Biomaterials for Healing Chronic Wounds

dermal wound dressing; wound dressings; wound healing

B. D. Almquist, MIT, Cambridge, MA

S. Castleberry, MIT, Cambridge, Massachusetts

P. T. Hammond, MIT, Cambridge, Massachusetts

859

Multivalent Sonic Hedgehog-Hyaluronic Acid Conjugates for Enhanced Neovascularization During Diabetic Wound Healing

dermal wound dressing; tissue engineering; wound healing

B. W. Han, University of California, Berkeley, Berkeley, CA

W. Jackson, University of California, Berkeley, Berkeley, California

H. Layman, University of California, San Francisco, San Fancisco, California

N. A. Rode, University of California, Berkeley, Berkeley, California

D. Dashti, University of California, Berkeley, Berkeley, California

A. Conway, University of California, Berkeley, Berkeley, California

N. Boudreau, University of California, San Francisco, San Francisco, California

D. Schaffer, University of California, Berkeley, Berkeley, California

K. E. Healy, University of California, Berkeley, Berkeley, California

860

Decellularized Extracellular Matrix Microparticles Support Fibroblast Growth and are a Vehicle for Cellular Delivery in a Model of Anastomosis Healing

collagen; extracellular matrix; wound healing

D. Hoganson, Washington University in St. Louis, St. Louis, MO

G. E. Owens, California Institute of Technology, Pasadena, California

E. K. Bassett, Massachusetts General Hospital, Boston, Massachusetts

A. M. Meppelink, Massachusetts General Hospital, Boston, Massachusetts

C. Bowley, DSM Biomedical, Exton, Pennsylvania

C. J. Hinkel, Washington University in St. Louis, St. Louis, Missouri

E. B. Finkelstein, Syracuse University, Syracuse, New York

S. M. Goldman, DSM Biomedical, Exton, Pennsylvania

J. P. Vacanti, Massachusetts General Hospital, Boston, Massachusetts

861

Development of Supercritical CO2-Treated Human Amniotic Membrane Combined with Adipose Derived Stem Cells for Wound Treatment

dermal wound dressing; sterilization; wound healing

J. Wehmeyer, U.S. Army Institute of Surgical Research, Fort Sam Houston, TX

862

Development of modified collagen films containing red propolis extracts to wound healing application

wound healing

J. C. Cardoso, Universidade Tiradentes, Watertown, MA

863

Controlling the Delivery of Vascular Endothelial Growth Factor and Platelet Derived Growth Factor

angiogenesis/neovascularization; controlled release; growth factor

L. Kelly, University of Sheffield, Sheffield, United Kingdom (Great Britain)

L. Platt, University of Sheffield, Sheffield, United Kingdom (Great Britain)

S. MacNeil, University of Sheffield, Sheffield, United Kingdom (Great Britain)

P. Genever, University of York, York, United Kingdom (Great Britain)

S. Rimmer, University of Sheffield, Sheffield, United Kingdom (Great Britain)

864

AnastomoSEAL – Biopolymeric patches for the treatment of colorectal anastomosis

biocompatibility/soft tissue; bioresorbable; wound healing

M. Dornish, FMC BioPolymer AS, Sandvika, Norway

S. Paolettk, University of Trieste, Trieste, Italy

N. Bouvy, University of Maastricht, Maastricht, Netherlands

M. Bosco, SIGEA SRL, Trieste, Italy

M. Foulc, RESCOLL, Pessac, France

W. Fediuk, I.E. "IMPULS", Gdansk, Poland

865

Absorbable Polyurethanes for Wound Healing Applications

absorbable; polyurethane(s); wound healing

N. Srivastava, Bezwada Biomedical, LLC, Hillsborough, NJ

866

Factors Associated with the Ideal Donor Site Dressing for Burn Patients after Split-Thickness Skin Grafting

adhesion; burn

R. Jindani, North Carolina State University, Raleigh, NC

867

Development of Mucoadhesive Films with Increased Residence Time for Treatment of Local Disorders

adhesion; controlled release; drug delivery/release

S. k. RAMINENI, University Of Kentucky, Lexington, KY, KY

868

Layer-by-Layer Delivery of siRNA

nanoassembled devices; scaffolds; wound healing

S. Castleberry, Massachusetts Institute of Technology, Cambridge, MA

P. Hammond, Massachusetts Institute of Technology, Cambridge, Massachusetts

869

Wound healing processes using Punica granatum Linn extracts incorporated in collagen based films

bioactive material; wound dressings

W. A. Araujo, Universidade Tiradentes, Watertown, MA

964

Antibacterial microfilm dressing with silver-nanoparticles promotes healing of contaminated excisional wounds

antimicrobial; dermal wound dressing; infection

A. Agarwal, Imbed Biosciences Inc, Madison, WI

T. B. Nelson, Imbed Biosciences, Inc, Madison, Wisconsin

P. R. Kierski, University of Wisconsin-Madison, Madison, Wisconsin

M. Budianto, University of Wisconsin-Madison, Madison, Wisconsin

C. J. Murphy, University of California, Davis, Davis, California

M. J. Schurr, University of Colorado, Denver, Aurora, Colorado

C. J. Czuprynski, University of Wisconsin-Madison, Madison, Wisconsin

N. L. Abbott, University of Wisconsin-Madison, Madison, Wisconsin

J. F. McAnulty, University of Wisconsin-Madison, Madison, Wisconsin

965

Evaluating Performance of Hydrogel-Based Adhesives for Soft Tissue Applications

adhesion; biomechanics; hydrogel

L. Sanders, Clemson University, Clemson, SC

966

Use of Tryptophan to Prevent Pseudomonas aeruginosa Biofilm Growth on Wound Dressings

cytotoxicity; infection; wound dressings

K. S. Brandenburg, University of Wisconsin-Madison, Madison, WI

J. F. McAnulty, University of Wisconsin-Madison, Madison, Wisconsin

N. L. Abbott, University of Wisconsin-Madison, Madison, Wisconsin

C. J. Murphy, University of California-Davis, Davis, California

M. J. Schurr, University of Colorado-Denver, Aurora, Colorado

N. Shah, University of California-Davis, Davis, California

A. Agarwal, Imbed Biosicences Inc, Madison, Wisconsin

C. J. Czuprynski, University of Wisconsin-Madison, Madison, Wisconsin

967

Dendritic Hydrogels as Portable Systems for Hemostasis of Abdominal and Extremity Wounds

hemostasis; hydrogel; wound dressings

C. Ghobril, Boston University, Boston, MA

A. Nazarian, Beth Israel Deaconess Medical Center, Boston, Massachusetts

E. Rodriguez, Beth Israel Deaconess Medical Center, Boston, Massachusetts

M. Grinstaff, Boston University, Boston, Massachusetts