Con-current Oral Abstract Presentations Session 4

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Advances in Ophthalmic Biomaterials and Ocular Drug-Delivery2

126

Corneal Stromal Stem Cells Versus Corneal Fibroblasts in Generating Structurally Appropriate Corneal Stromal Tissue

cornea/conjunctiva; extracellular matrix; stem/progenitor cells

J. Wu, University of Pittsburgh School of Medicine, Pittsburgh, PA

Y. Du, University of Pittsburgh School of Medicine, Pittsburgh, PA, Pennsylvania

J. L. Funderburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

W. R. Wagner, University of Pittsburgh, Pittsburgh, Pennsylvania

127

Engineered Basement Membranes for Regeneration of the Corneal Endothelium

cornea/conjunctiva; endothelial cells; ophthalmic

A. W. Feinberg, Carnegie Mellon University, Pittsburgh, PA

R. N. Palchesko, Carnegie Mellon University, Pittsburgh, Pennsylvania

O. Creasey, University of Pittsburgh, Pittsburgh, Pennsylvania

J. L. Funerburgh, University of Pittsburgh, Pittsburgh, Pennsylvania

128

Chemical modification of hyaluronan: Improving hyaluronan as a wetting agent for contact lenses.

ophthalmic

S. Paterson, McMaster University, Hamilton, ON, Canada

129

Phenylboronic Acid Modified Mucoadhesive Hydrogel Materials for Ophthalmic Drug delivery Applications

adhesion; drug delivery/release; ophthalmic

L. Liu, McMaster University, Canada, Hamilton, ON, Canada

H. D. Sheardown, McMaster University, Canada, Hamilton, Ontario, Canada

130

Poly(Ethylene Glycol)-Hyaluronic Acid Antioxidant Hydrogels for Prevention of Iatrogenic Cataracts

coating(s); eye; hydrogel

M. G. O'Toole, University of Louisville, Louisville, KY

R. M. Rostosky, University of Louisville, Louisville, Kentucky

T. H. Tezel, University of Louisville, Louisville, Kentucky

A. S. Gobin, University of Louisville, Louisville, Kentucky

131

Effect of E-Beam Sterilization on Optical and Rheological Properties of Some Viscoelastic Products

viscoelastic; viscosity

C. B. Hu, Abbott Medical Optics, Santa Ana, CA

H. Powell, Abbott Medical Optics, Santa Ana, California

Advances in Tissue Engineering Scaffolding2

132

Gelatin methacrylate (GelMA) and agarose hydrogels as a smart platform for bioprinting biomimetic vascular networks in 3D tissue engineering constructs

endothelial cells; hydrogel; vascular

L. E. Bertassoni, Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology; Faculty of Dentistry, University of Sydney, Aus, Cambridge, MA

M. Cecconi, 1. Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School; 2. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology;, Cambridge, Massachusetts

P. H. Molin, 1. Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School; 2. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology;, Cambridge, Massachusetts

E. S. Martinez-Martinez, 1. Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School; 2. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts

M. Nikkhah, 1. Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School; 2. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts

A. Khademhosseini, Center for Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology;  Wyss Institute for Biologically Inspired Engin, Cambridge, Massachusetts

133

Design and Analysis of Flexible Composite Scaffolds for Engineered Ear

collagen; scaffolds; tissue engineering

T. M. Cervantes, Massachusetts General Hospital, Boston, MA

E. K. Bassett, Massachusetts General Hospital, Boston, Massachusetts

A. Tseng, Massachusetts General Hospital, Boston, Massachusetts

A. Kimura, Massachusetts General Hospital, Boston, Massachusetts

N. Roscioli, Kensey Nash Corporation, Exton, Pennsylvania

R. Gupta, Massachusetts General Hospital, Boston, Massachusetts

M. A. Randolph, Massachusetts General Hospital, Boston, Massachusetts

J. P. Vacanti, Massachusetts General Hospital, Boston, Massachusetts

I. Pomerantseva, Massachusetts General Hospital, Boston, Massachusetts

C. A. Sundback, Massachusetts General Hospital, Boston, Massachusetts

134

Controllably degradable self-assembling peptide materials for tissue engineering

biodegradation; hydrogel; tissue engineering

Y. F. Tian, University of Chicago, Chicago, IL

135

Formation of Endothelial Cell Networks in Hydrogel Scaffolds Assembled from Modular Collagen-Fibrin Microenvironments

angiogenesis/neovascularization; collagen; fibrin

A. W. Peterson, University of Michigan, Ann Arbor, MI

A. W. Peterson, University of Michigan, Ann Arbor, Michigan

R. R. Rao, University of Michigan, Ann Arbor, Michigan

A. Y. Rioja, University of Michigan, Ann Arbor, Michigan

A. J. Putnam, University of Michigan, Ann Arbor, Michigan

J. P. Stegemann, University of Michigan, Ann Arbor, Michigan

136

Scaffold pore size controls chondrogenic differentiation of human mesenchymal stem cells and cartilage formation in vitro and in vivo

cartilage; cell differentiation; phase separated polymer

M. J. Gupte, University of Michigan, Ann Arbor, MI

J. Hu, University of Michigan, Ann Arbor, Michigan

H. Ma, University of Michigan, Ann Arbor, Michigan

G. Feng, University of Michigan, Ann Arbor, Michigan

K. Feng, University of Michigan, Ann Arbor, Michigan

G. Xiao, University of Michigan, Ann Arbor, Michigan

P. X. Ma, University of Michigan, Ann Arbor, Michigan

137

Novel Porous Polycaprolactone Fumarate (PCLF) Scaffold for Adipocyte Derived Mesenchymal Stem Cell Engineering and Platelet Lysate Enhanced Ligament Differentiation

biomolecular engineering; ligament(s); orthopedic

S. Chase, Mayo Clinic, Rochester, MN

E. R. Wagner, Mayo Clinic, Rochester, Minnesota

S. Chase, Mayo Clinic, Rochester, Minnesota

D. Bravo, Mayo Clinic, Rochester, Minnesota

M. Dadsetan, Mayo Clinic, Rochester, Minnesota

S. Kakar, Mayo Clinic, Rochester, Minnesota

M. Yaszemski, Mayo Clinic, Rochester, Minnesota

Benchtop Tissue Surrogates to Model Drug Uptake and Efficacy

139

Quantification of Ultrasound-Mediated Drug Delivery using an In Vitro Flow Chamber

cardiovascular; drug delivery/release; in vitro

J. L. Chen, University of Virginia, Charlottesville, VA

A. J. Dixon, University of Virginia, Charlottesville, Virginia

A. H. Dhanaliwala, University of Virginia, Charlottesville, Virginia

J. A. Hossack, University of Virginia, Charlottesville, Virginia

140

Engineering a Three-Dimensional In Vitro Model of Bone Sarcoma for Drug-Testing

bone; tissue engineering; tumor

L. Fong, Rice University, Houston, TX

S. Lamhamedi Cherradi, The University of Texas MD Anderson Cancer Center, Houston, Texas

E. Burdett, Rice University, Houston, Texas

V. Ramamoorthy, The University of Texas MD Anderson Cancer Center, Houston, Texas

A. Lazar, The University of Texas MD Anderson Cancer Center, Houston, Texas

K. Kasper, Rice University, Houston, Texas

M. Farach-Carson, Rice University, Houston, Texas

D. Vishwamitra, The University of Texas MD Anderson Cancer Center, Houston, Texas

E. Demicco, Mount Sinai Medical Center, New York, New York

B. Menegaz, The University of Texas MD Anderson Cancer Center, Houston, Texas

H. Amin, The University of Texas MD Anderson Cancer Center, Houston, Texas

J. Ludwig, The University of Texas MD Anderson Cancer Center, Houston, Texas

A. Mikos, Rice University, Houston, Texas

141

Electrospun Nanofiber-supported Collagen Films: in vitro Modeling of Epithelial and Endothelial Tissues

collagen; extracellular matrix; tissue culture

C. M. Neville, Massachusetts General Hospital, Boston, MA

K. M. Kulig, Massachusetts General Hospital, Boston, Massachusetts

S. Lauterbach, Ludwig-Maximilians-University, Munich, Germany

J. P. Vacanti, Massachusetts General Hospital, Boston, Massachusetts

C. R. Wittmer, Massachusetts General Hospital, Boston, Massachusetts

C. J. Neville, Stony Brook University, Stony Brook, New York

142

Decellularized Skeletal Muscle Extracellular Matrix as an in vitro Model for Intramuscular Drug Development

drug delivery/release; extracellular matrix; test method

J. J. Wang, University of California, San Diego, La Jolla, CA

K. L. Christman, University of California, San Diego, La Jolla, California

G. R. Boss, University of California, San Diego, La Jolla, California

Biomaterial Microenvironment for Stem Cell-Based Cartilage and Intervertebral Disc Regeneration

144

Tunable Electrospun Hyaluronic Acid Scaffolds to Mimic the Microenvironment of Articular Cartilage

articular cartilage; biomimetic; stem/progenitor cells

I. L. Kim, University of Pennsylvania, Philadelphia, PA

S. Khetan, University of Pennsylvania, Philadelphia, Pennsylvania

B. M. Baker, University of Pennsylvania, Philadelphia, Pennsylvania

C. S. Chen, University of Pennsylvania, Philadelphia, Pennsylvania

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

145

Striking The Balance Between Optimal Cell Response And Enhanced Tissue Repair In A 3D Multi-Layered Scaffold For Cartilage Repair

articular cartilage; in vivo; scaffolds

V. Barron, National University of Ireland, Galway, Galway, Ireland

M. Neary, National University of Ireland, Galway, Galway, Ireland

G. O'Malley, National University of Ireland, Galway, Galway, Ireland

N. Rooney, Proxy Biomedical, Galway, Ireland

F. Barry, National University of Ireland, Galway, Galway, Ireland

M. Murphy, National University of Ireland, Galway, Galway, Ireland

146

Covalently Tethered Transforming Growth Factor Beta-1 in PEG Hydrogels Expedites Cartilage ECM Production of Encapsulated Primary Chondrocytes.

articular cartilage; orthopedic; tissue engineering

B. V. Sridhar, University of Colorado, Denver, CO

147

Visible light inducible chitosan composite hydrogel containing collagen or chondroitin sulfate for cartilage tissue engineering

cartilage; hydrogel; tissue engineering

B. Choi, University of California, Los Angeles, Los Angeles, CA

Developing the Next Generation of Cardiovascular Devices - From Concept to Implantation (An Industry Perspective)

148

A Nanofibrous Self-Sealing Bioactive Hemodialysis Access Graft

hemodialysis; nanotechnology; vascular graft

S. G. Pathan, BioSurfaces Inc., Ashland, MA

D. W. Nelson, BioSurfaces Inc., Ashland, Massachusetts

S. M. Ali, BioSurfaces Inc., Ashland, Massachusetts

M. J. Bide, University of Rhode Island, Kingston, Rhode Island

L. M. Fitzgerald, BioSurfaces Inc., Ashland, Massachusetts

J. R. Araya, BioSurfaces Inc., Ashland, Massachusetts

T. E. Phaneuf, BioSurfaces Inc., Ashland, Massachusetts

M. A. Contreras, Beth Israel Deaconess Medical Center, Boston, Massachusetts

T. Phaneuf, BioSurfaces Inc., Ashland, Massachusetts

M. D. Phaneuf, BioSurfaces Inc., Ashland, Massachusetts

149

Novel polymer based Trans Catheter Aortic Valve Implant (TAVI)

heart valve; polymer

A. Perera, Direct Flow Medical, santa rosa, CA

150

Bioabsorbable Stents Made by Rapid Fabrication System

absorbable; drug delivery/release; stents

G. Shi, 3D Biotek, LLC, North Brunswick, NJ

151

Synthesis and Analysis of Electrospun Suture for Localized Infection Prevention

infection; nanomaterials/nanophase; nanotechnology

D. W. Nelson, BioSurfaces, Inc., Ashland, MA

S. G. Pathan, BioSurfaces, Inc., Ashland, Massachusetts

M. J. Bide, University of Rhode Island, Kingston, Rhode Island

C. B. Meeks, BioSurfaces, Inc., Tufts University, Ashland, Massachusetts

M. A. Contreras, Beth Israel Deaconess Medical Center, Boston, Massachusetts

T. M. Phaneuf, BioSurfaces, Inc., Ashland, Massachusetts

M. D. Phaneuf, BioSurfaces, Inc., Ashland, Massachusetts

152

The Development of In Vitro Abrasion Test Method for Textile and Metal Components of Endovascular Stent Grafts

vascular graft; vascular prosthesis; wear

T. Yao, North Carolina State University, Raleigh, NC

153

Effects of Coating Methods and Solvents on the Deposition of Paclitaxel on Self-Assembled Monolayers Coated Stents

drug delivery/release; stents; surface characterization

S. Lamichhane, The University of South Dakota, Sioux Falls, SD

A. Gallo, The University of South Dakota, Sioux Falls, South Dakota

G. Mani, The University of South Dakota, Sioux Falls, South Dakota

Translational Research in Nano-biomaterials

154

Combined Optical and Magnetic Resonance Imaging Enables Noninvasive Trafficking of Tissue Regeneration

biodegradation; molecular imaging; scaffolds

H. Choi, Harvard Medical School, Boston, MA

155

Clinically Translated, Thermoplastic Biomaterial as Absorbable Scaffold for Functional Regeneration of Vascular, Dermal and Other Tissues: Biocoacervation of Purified Extracellular Matrix (ECM) Protein and Glycosaminoglycan

absorbable; regenerative medicine; scaffolds

D. B. Masters, Gel-Del Technologies, Inc, St. Paul, MN

L. K. Hansen, WuXi AppTec, St. Paul, Minnesota

R. A. Meyer, Gel-Del Technologies, Inc., St. Paul, Minnesota

156

Biocompatibility Evaluation of Poly(N-isopropylacrylamide)-based Hydrogels for Craniofacial Bone Regeneration

biocompatibility/soft tissue; hydrogel; in vivo

T. N. Vo, Rice University, Houston, TX

A. K. Ekenseair, Rice University, Houston, Texas

P. Spicer, Rice University, Houston, Texas

B. M. Watson, Rice University, Houston, Texas

F. Kasper, Rice University, Houston, Texas

A. G. Mikos, Rice University, Houston, Texas

157

Transdermal Gelation of Hyaluronic acid Hydrogels with Gold Nanorods and Near-Infrared Light

hydrogel; laser; nanotechnology

W. M. Gramlich, University of Pennsylvania, Philadelphia, PA

J. L. Holloway, University of Pennsylvania, Philadelphia, Pennsylvania

R. Rai, University of Pennsylvania, Philadelphia, Pennsylvania

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

158

A Gold Nanoparticle-Based System to Monitor Mesenchymal Stem Cells Delivered via a PEGylated Fibrin Matrix for Ischemic Repair

angiogenesis/neovascularization; nanomaterials/nanophase; nanotechnology

L. M. Ricles, The University of Texas at Austin, Austin, TX

S. Nam, The University of Texas at Austin, Austin, Texas

S. Y. Emelianov, The University of Texas at Austin, Austin, Texas

L. J. Suggs, The University of Texas at Austin, Austin, Texas

159

Prevention of Peritendinous Adhesions with Electrospun Poly(caprolactone)-graft-chitosan Nanofibrous Mats

surface modification; tissue adhesion

S. Chen, Department of Chemical and Materials Engineering Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan 333, ROC, Tao-Yuan, Taiwan

C. Chen, Department of Chemical and Materials Engineering Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan 333, ROC., Tao-Yuan, Taiwan

J. Chen, Department of Chemical and Materials Engineering Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan 333, ROC, Tao-Yuan, Taiwan