3 Minute Thesis Competition

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm

About

Calling ALL Graduate Students!

The SFB National Student Section will be hosting a 3-Minute Thesis Competition at the virtual SFB 2021 Annual Conference! The event will feature cash prizes and an all-star judging panel with people you want to impress.

Register no later than Friday, April 9th at 11:59 PM

In a 3-Minute Thesis ("3MT") Competition, graduate students present a single static slide as a compelling summary of their dissertation research and its broader impacts. Presentations must be at most three minutes and targeted to a non-technical audience. 3MT is a great way to practice your presentation skills and think about how to convey the significance of your work.

Our 3MT Competition is scheduled for Thursday, April 22nd from 1:45-3:15 CST. We are happy to announce that the event has been sponsored by the Royal Society of Chemistry (RSC) Journal of Materials Chemistry B, Biomaterials Science, and Materials Advances, allowing us to provide the following prizes:

$250 for 1st place
$200 for 2nd place
$150 for 3rd place

Finally, we are excited to announce our judging panel members:

Nicholas Peppas from University of Texas at Austin
Jennifer Elisseeff from Johns Hopkins University
Jason Burdick from University of Pennsylvania

Be sure to register by April 9th and we will send more detailed instructions soon after!

Questions may be sent to Deanna (dbousalis@ufl.edu) or Nick (fisc0456@umn.edu)

Abstracts

Abstracts will be available for download on April 20, 2021.

  • Moderators: Deanna Bousalis and Nicholas Fischer

Biomaterials for Regenerative Engineering - 2

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm
Track: Tissue Engineering and Regenerative Medicine
Room: Virtual

About

Due to disease, degeneration, or trauma, there is a tremendous need to repair damaged tissues and organs. Although surgical replacement can be performed to address this issue, the insufficient number of donors greatly limits the applicability of this approach. Therefore, it is essential to develop engineered multifunctional biomaterials to promote tissue regeneration. Regenerative engineering combines biomaterial-based approaches with stem cell therapies and developmental biology to regenerate or repair tissues and organs. This symposium will cover tunable biocompatible materials such as hydrogels, fibers, proteins, carbohydrates, nano/micro-porous scaffolds, and metals, to modulate cellular microenvironments. The biomaterials that can direct cell fate and promote differentiation will also be highlighted by this session. Moreover, the biomaterials that can facilitate drug delivery and immunomodulation will be covered through oral and poster presentations. Furthermore, we will include discussions for the development and commercialization of various medical devices such as blood contacting implants, prostheses, and pacemakers in the session. In addition to engineering approaches, we will provide discussions on clinical translation of biomaterial-based strategies. We will also include topics that are relevant to the rapidly changing circumstances associated with the Novel Coronavirus to improve patient putcomes. We expect that our interdisciplinary session including material science, chemistry, biology, engineering, and medicine will be of great significance to the clinicians, industry members and professors in academia.

Moderator:
Gulden Camci-Unal, PhD

Abstracts

Abstracts will be available for download on April 20, 2021.

  • 169. Multiphase, Vascularized Bone Constructs Comprised of Modular Vascular and Osteogenic Microtissues, Nicholas Schott, Jan StegemannThe University of Michigan, Ann Arbor, MI, USA

  • 170. Vascularization of Degradable PEG-Norbornene Hydrogels via Coculture of Endothelial and Stromal Cells, Nicole Friend, MSE, Jan Stegemann, PhD, Andrew Putnam, PhDUniversity of Michigan, Ann Arbor, MI, USA

  • 171. Nucleic Acid-Collagen Complexes (NACC): Engineering Tunable Hard and Soft ECM Mimics, Bryan James, Sophia Saenz, Paxton James, Josephine AllenUniversity of Florida, Gainesville, FL, USA

  • 172. Unconventional Biomaterials for Regenerative Engineering, Gulden Camci-UnalUniversity of Massachusetts Lowell, Lowell, MA, USA

  • 173. Designer, Injectable Gels to Prevent Transplanted Schwann Cell Loss During Spinal Cord Injury Therapy, Vanessa Doulames, PhD1, Laura Marquardt, PhD1,2, Alice Wang2, Karen Dubbin, PhD2, Riley Suhar2, Michael Kratochvil, PhD2,3, Zachary Medress, MD1, Giles Plant, PhD1, Sarah Heilshorn, PhD21Stanford University School of Medicine, Stanford, CA, USA, 2Stanford University, Stanford, CA, USA, 3Stanford University SoM, Stanford, CA, USA

  • 174. Development of a Hyaluronan Polymer-Protein Conjugate for Peripheral Nerve Applications, Mary Kasper, Madison Cydis, Abdullah Afridi, Christine Schmidt, Ph.D.University of Florida, Gainesville, FL, USA

Cardiovascular Biomaterials SIG 2

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm
Track: Cardiovascular Biomaterials
Room: Virtual

About

The Cardiovascular Special Interest Group has the mission to foster the professional interaction and address the common concerns of academic and industrial scientists and engineers, clinicians, and regulatory professionals concerned with the discovery, research, development, and use of biomaterials for cardiovascular devices and implants.

Moderators:
Yi Hong, PhD
C. LaShan Simpson, PhD

Abstracts

Abstracts will be available for download on April 20, 2021.

  • 175. Heparin Coating Improves Thromboresistance In Glutaraldehyde Processed Bovine Pericardium: A Possible Application For Bioprosthetic Heart Valve, Devika S L, M.Sc, Maneesha Gurudas, M.Sc, Jesna P.V, M.Sc, M.Phil, Anugya Bhatt, Ph.D, Umashankar P.R, PhDSree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India

  • 168. Mechanical Performance of a Hydrogel-Fiber Mesh Composite as a Synthetic Heart Valve Material, Shruti Motiwale1,2, Madeleine Russell3, Megan Wancura3, Andrew Robinson3, Elizabeth Cosgriff-Hernandez3, Michael Sacks1,31James T. Willerson Center for Cardiovascular Modeling and Simulation, Oden Institute, Austin, TX, USA, 2Department of Mechanical Engineering, University of Texas at Austin, Austin, TX, USA, 3Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA

  • 177. New Fluorinated Alkoxyphosphazene Biomaterials with Improved Biocompatibility, Lichong Xu Xu, PhD1, Chen Chen, PhD2, Harry Allcock, PhD2, Christopher Siedlecki, PhD11Penn State University College of Medicine, Hershey, PA, USA, 2The Pennsylvania State University, University Park, PA, USA

  • 178. Injectable hydrogel electrodes for treatment of ventricular arrhythmias, Gabriel Rodriguez-Rivera1, Malgorzata Chwatko, PhD2, Allison Post, PhD3, Mathews John3, Skylar Buchan3, Christina Waldron2, Mehdi Razavi, PhD3, Elizabeth Cosgriff-Hernandez21The University of Texas at Austin, Austin, TX, USA, 2The University of Texas at Austin', Austin, TX, USA, 3Texas Heart Institute, Houston, TX, USA

  • 179. Biovesicle delivery of connexin 43 improves synchronous beating of hiPSC derived Cardiomyocytes, Nima Momtahan, PhD, Cody Crosby, PhDUniversity of Texas at Austin, Austin, TX, USA

  • 180. Peritoneal Pre-conditioning Impacts Vascular Graft Long-term Patency and Remodeling, Mahyar Sameti, PhD, Mozhgan Shojaee, PhD, Bayan Saleh, Chris Bashur, PhDFlorida Institute of Technology, Melbourne, FL, USA

Drug Delivery SIG 2

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm
Track: Therapeutic Delivery
Room: Virtual

About

The Drug Delivery Special Interest Group will deal with the science and technology of controlled release of active agents from delivery systems. Controlled drug release is achieved by the use of diffusion, chemical reactions, dissolutions or osmosis, used either singly or in combination. While the vast majority of such delivery devices are based on polymers, controlled release can also be achieved by the use of mechanical pumps. In a broader sense, controlled release also involves control over the site of action of the active agent, using the active agent using pro-drugs, targetable water soluble polymers or various microparticulate systems. Relevant aspects of toxicology, bioavailability, pharmacokinetics, and biocompatibility are also included.

Moderators:
Michael Mitchell, PhD
Omid Veiseh, PhD

Abstracts

Abstracts will be available for download on April 20, 2021.

  • 181. Development of Antimicrobial Biochanin A Poly(beta amino ester) Polymers, Kelley Wiegman1, Michael Flythe2, Zach Hilt1, Thomas Dziubla11University of Kentucky, Lexington, KY, USA, 2U. S. Department of Agriculture, Lexington, KY, USA

  • 182. Bio-responsive Hydrogels for On-Demand Delivery of Anti-Cancer Therapeutics, Fei Fan, Grace Petrosini, Sharon Stack, Donny Hanjaya-PutraUniversity of Notre Dame, Notre Dame, IN, USA

  • 183. Effects of Spatial Organization and Histidine Tag on Efficacy of Intracellular Protein Delivery System, Wei Lv, PhD, Anshul Dhankher, Talmage Studstill, Julie Champion, PhDGeorgia Institute of Technology, Atlanta, GA, USA

  • 184. Drug Release from Ace-DEX Particles: An Experimental and Mathematical Model, Rebeca Stiepel1, Erik Pena2, Matthew Gallovic, PhD3, Christopher Genito4, Eric Bachelder, PhD1, Kristy Ainslie, PhD1,2,41Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 2University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, USA, 3IMMvention Therapeutix, Durham, NC, USA, 4University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

  • 185. Using a miR-451 Inhibitor May Mitigate OA Development and Progression In Vivo Following Anterior Cruciate Ligament Injury, Kayla Scott, B.S.1, D. Joshua Cohen, M.D.1, Dane Nielson1, Gloria Kim1, Mark Grinstaff, Ph.D.2, Anisha Joenathan, B.S.2, Brian Snyder, M.D., Ph.D.3, Zvi Schwartz, D.M.D., Ph.D.1,4, Barbara Boyan, Ph.D.1,51Virigina Commonwealth University, Richmond, VA, USA, 2Boston University, Boston, MA, USA, 3Harvard Medical School, Boston, MA, USA, 4University of Texas Health Science Center at San Antonio, San Antonio, TX, USA, 5Georgia Institute of Technology, Georgia, GA, USA

  • 186. Simple Biodegradable Polyester for Stent-Based Drug Delivery, Kathleen Young, Audrey Lord, Susan Kozawa, PhD, Horst von Recum, PhDCase Western Reserve University, Cleveland, OH, USA

Engineering Tissues with Immune Cells

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm
Track: Immunomodulatory Biomaterials
Room: Virtual

About

The combination of biomaterials and tissue engineering with cells of the immune system offers a powerful opportunity to create next-generation, immune-competent tissues. This session will highlight recent advances at the intersection of tissue engineering and immune engineering. Abstracts are solicited in any of the following categories: * Immunomodulatory biomaterials for regenerative medicine, including wound healing and grafts * Materials that create in vivo immune niches, e.g. to modulate autoimmunity or cancer * Engineering of immune-competent in vitro tissue models, including organoids and organs-on-chip * Other means to leveraging tissue-immune cell interactions to enhance tissue engineering strategies.

Moderators:
Rebecca Pompano, PhD
Kara Spiller, PhD

Abstracts

Abstracts will be available for download on April 20, 2021.

  • 187. Mesenchymal Stem Cell Modulation of the Synthetic Biomaterial Immune Microenvironment, Karen Martin, Rebecca Schneider, Andres Garcia, PhDGeorgia Institute of Technology, Atlanta, GA, USA

  • 188. Dynamic 3D Tracking of Pancreatic Islet and Immune Cell Interactions In Vitro, Magdalena Samojlik, MS1, Smit Patel1, Ying Li, PhD1,2, Scott Stimpson, PhD2, Leeana Peters2, Clayton Mathews, PhD2, Todd Brusko, PhD2, Edward Phelps, PhD1, Cherie Stabler, PhD11University of Florida, College of Engineering, Gainesville, FL, USA, 2University of Florida, College of Medicine, Gainesville, FL, USA

  • 189. Engineering a Synthetic Hydrogel Platform to Support Tolerogenic Trophoblast Organoids, Emily Slaby, Caitlin O'Brien, Jessica Weaver, PhDArizona State University, Tempe, AZ, USA

  • 190. Injectable T cell-loaded Hydrogel as a Localised Immunotherapy Reduces Tumour Growth in Mice, Nicholas Cunningham1,2, Tommy Malaret1,2, John Stagg3,4, Paméla Thébault3,4, Dominique Trudel3,4, Réjean Lapointe3,4, Sophie Lerouge1,2,41Centre de recherche du CHUM (CRCHUM), Montréal, QC, Canada, 2École de technologie supérieure (ETS), Montréal, QC, Canada, 3Institut du Cancer de Montréal, Montréal, QC, Canada, 4Université de Montréal, Montréal, QC, Canada

  • 191. In vitro Generation of Antibody Class-Switched Primary B cells using Liposome-Based Presentation of Antigen, Liana Kramer, ScM1, Hannah Song, PhD1, Ankur Singh, PhD1,2, Krishendu Roy, PhD11Georgia Institute of Technology and Emory University, Atlanta, GA, USA, 2Georgia Institute of Technology, Atlanta, GA, USA

Panel: Identifying the Commercial Value of Tissue Regenerative Biomaterials

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm
Track: Tissue Engineering and Regenerative Medicine
Room: Virtual

About

Medical devices for Tissue Regeneration bear extreme significance in Biomaterials science. This session intends to address the hurdles in commercialization of the same. FDA as a regulatory agency monitoring the safety & efficacy of devices, can further enhance their scientific interactions with relevant medical biology/biotech societies including our Society for Biomaterials (SFB). CMS as the payor agency declares the product value decided by the Relative value Update Committee (RUC) comprised of 31 physicians from the societies affiliated with American Medical Association (AMA). No input seems to be obtained from basic scientific/biotechnology societies including SFB. To conclude, proper technical inputs from FDA and other relevant scientific societies like SFB are indispensable. Our proposal is to form a consortium of “FDA, CMS, the scientific groups (specifically SFB), and the clinical societies under AMA,” to determine the reimbursement value of medical devices supervised by the department of Human Health Services (HHS).

Abstracts

Abstracts will be available for download on April 20, 2021.

  • Moderator: Dr. Subramanian Gunasekaran, PhD

Translational Orthopedic Biomaterials: Progress and Challenges *BTI*

Timeslot: Thursday, April 22, 2021 - 1:45pm to 3:15pm
Room: Virtual

About

There are increasing demands for biomaterials that are responsive to local stimuli, and/or play multiple biological roles in a single application. The recent developments and breakthroughs of biomaterials with multiple biological functions and those that may contribute to COVID-9 treatments will be reported along with the challenges and translational studies. Progress in biomaterials like metals (including degradable materials), ceramics, and polymers for orthopedic applications will be highlighted. Technology and commercial challenges are also welcome to be presented. Mixed presentations from the U.S., Canada, Europe, and other countries are expected.

Moderators:
Bingyun Li, PhD
Malcom Xing, PhD

Abstracts

Abstracts will be available for download on April 20, 2021.

  • 193. Reliability of Fused Filament Fabrication for 3D Printing Multifunctional Ag-doped Bioactive Glass-Ceramic Scaffolds Towards Bone Tissue Regeneration, Adam Marsh, BS, Yaozhong Zhang, PhD, Aljoscha Roch, PhD, Xanthippi Chatzistavrou, PhDMichigan State University, East Lansing, MI, USA

  • 194. Biomimetic Scaffolds Composed of Degradable Polymers to Enhance Bone Regeneration, Ben Zhang, Yingchao Su, Juncen Zhou, Donghui ZhuThe State University of New York at Stony Brook, Stony Brook, NY, USA

  • 195. UVA-activated, injectable bioadhesive composites with controlled mechanical properties, Ivan Djordjevic1, Terry Steele1, Gautama Wicaksono1, Francesco Baino21Nanyang Technological University, Singapore, Singapore, 2Politecnico di Torino, Torino, Italy

  • 197. Things You Never Learned About Corrosion and Tribocorrosion of Metallic Biomaterials, Jeremy L. Gilbert Department of Bioengineering, Clemson University, Clemson - MUSC Bioengineering Program, Medical University of South Carolina, Charleston, SC 20425

Invited Speaker(s)