Antimicrobial and Antibiofilm Biomaterials Strategies
500. Enhanced Antibacterial Titanium Surface Developed using Hydrothermal Treatment, Ketul Popat, PhD, Vignesh Manivasagam, MS, Colorado State University, Fort Collins, CO, USA
501. Bacterial bioburden analysis of on-label povidone-iodine surgically prepared skin samples in porcine model support patient-originated infection hypothesis, Rose Godfrey1, Hannah Duffy1, Dustin Williams, PhD1,2, Nicholas Ashton, PhD1, 1University of Utah, Salt Lake City, UT, USA, 2Uniformed Services University of the Health Sciences, Bethesda, MD, USA
502. Toluidine Blue Ortho @ Magnetic Photosensitizing Nanoplatform: Antibiofilm Effect against Thick Constant-depth-film-fermenter Biofilms, Abdulrahman Balhaddad1,2, Lamia Mokeem2, Michael Weir2, Huakun Xu2, Mary Anne Melo2, 1Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia, 2University of Maryland, Baltimore, Baltimore, MD, USA
503. Manipulated Bacteria Interactions with Functionalized Gold Nanoparticles for Rapid Bacteria Detections and Infection Control, Jue Wang1, Junfeng Liang, PhD1, Jocelyn Tan2, 1Stevens Institute of Technology, Hoboken, NJ, USA, 2Ridge High School, Basking Ridge, NJ, USA
504. Efficient Bacteria Killing by Dental Adhesives with Benzyldimethyldodecylammonium Chloride, Lamia Mokeem, BDS, MSD, AbdulRahman Balhaddad, BDS, MSD, PhD, Mary Anne Melo, DDS, MSc, PhD, FADM, University of Maryland School of Dentistry, Baltimore, MD, USA
506. A new strategy to combat biofilm antibiotic tolerance: Eradication of bacterial persister cells by targeting membrane potential, Sweta Roy, Ali Adem, PhD, Huan Gu, PhD, Shikha Nangia, Professor, Dacheng Ren, Professor, Syracuse University, Syracuse, NY, USA
507. First-in-Class Spray-On Antimicrobial Barrier Film Dressing, Jonathan Velasco, Rebecca McMahon, PhD, MBA, Kelly Leung, PhD, Joseph Salamone, PhD, Rochal Technologies, San Antonio, TX, USA
508. Erythromycin-Doped Nanofiber Coating Enhances Osseointegration and Inhibits Staphylococcus Aureus Induced Osteolysis, Dexter Powell, MD.1, Bin Wu, MD.1, Paula Dietz, MS.1, Therese Bou-Akl, MD., PhD.1,2, Weiping Ren, MD., PhD.1,2, David Markel, MD.1,2, 1Ascension Providence Hospital, Southfield, MI, USA, 2Wayne State University, Detroit, MI, USA
509. 3D-Printed Antibacterial Silicone Devices Based Nitric Oxide Release from S-nitrosothiol Crystals, Xuewei Wang, Hong Zhao, Wuwei Li, Yuanhang Yang, Virginia Commonwealth University, Richmond, VA, USA
510. Electrochemically Generated Hydrogen Peroxide for the Prevention of Biofilm Formation, Caelen Clark, Ph.D., Mark Ehrensberger, Ph.D., State University of New York at Buffalo, Buffalo, NY, USA
511. A Multifunctional Electrospun Wrap to Treat Infection and Enhance Bone Regeneration, Sarah Jones1, Taneidra Buie, PhD1, Annika Balakrishnan1, Evan He1, Joseph Wenke, PhD2, Elizabeth Cosgriff-Hernandez, PhD1, 1University of Texas at Austin, Austin, TX, USA, 2University of Texas Medical Branch, Austin, TX, USA
512. Moisture-Activated Antiviral Coating based on Mussel Adhesive Chemistry, Seyedehfatemeh Razaviamri, Sneha Singh, Zhongtian Zhang, James Manuel, Pegah Kord Forooshani, Caryn Heldt, Bruce P. Lee, Michigan Technological University, Houghton, MI, USA
514. Growth and Enzyme Inhibition of Streptococcus mutans Using Nanoceria, Alyssa Che, Sejal Gandhi, Adam Goodman, Emily Long, Kamal Patel, Herchel Patel, Vladimir Reukov, PhD, University of Georgia, Athens, GA, USA
515. Formulation of a Controlled Release Antibacterial Wound Protectant for Austere Environments, David Armbruster, MSE1, Charles Florek, PhD1, Eric Cozzone, MS1, Dustin Williams, PhD2, Annika Hylen2, 1DePuy Synthes, West Chester, PA, USA, 2University of Utah, Salt Lake City, UT, USA
516. Selenite and Strontium Co-substituted Hydroxyapatite: Preparation, Characterization, Antibacterial Activity, and In-vitro Biological Testing, Muhammad Maqbool1,2,3, Qaisar Nawaz1, Atiq Ur Rehman1, Mark Cresswell2, Phil Jackson2, Katrin Hurle4, Rainer Detsch1, Wolfgang H Goldmann5, Asma Tufail Shah6, Aldo R Boccaccini1, 1Institute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany, 2Lucideon Ltd., Queens Road, Penkhull, Stoke-on-Trent, Staffordshire, ST4 7LQ, UK, Stoke-on-Trent, United Kingdom, 3CAM Bioceramics B.V, Leiden, Netherlands, 4GeoZentrum Nordbayern - Mineralogy, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany, 5Department of Biophysics, University of Erlangen-Nuremberg, Erlangen, Germany, 6Interdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University, Lahore, Pakistan
517. Live Cell Imaging of Bacterial Biofilm Disruption by Cathodic Voltage-Controlled Electrical Stimulation, Jesse Schmitz, Tobius Menachem, Eric McDermott, Caelen Clark, Mark Ehrensberger, University at Buffalo, Buffalo, NY, USA
518. Computational Modeling of the Electrochemical Microenvironment Adjacent to Cathodically Stimulated Orthopedic Implants, Priyanshu Vishnoi, Elise Martin, PhD, Mary Canty, Jackson Hobble, Mark Swihart, Mark Ehrensberger1, 1University at Buffalo, State University of New York, Buffalo, NY, USA
519. Residual Platinum Plays a Substantial Role in Reducing Bacterial Attachment and Biofilm Development on the Surface of a Silorane-Based Bone Cement, Terence McIff, PhD, MBA1, Grahmm Funk, BSc1, Elizabeth Menuey, PhD2, Kara Hageman, MS1, Kathleen Kilway, PhD2, 1University of Kansas Medical Center, Kansas City, KS, USA, 2University of Missouri - Kansas City, Kansas City, MO, USA
520. Flame-made calcium phosphate nanoparticles: a novel platform for antimicrobial drug delivery, Vasiliki Tsikourkitoudi, PhD, Georgios Sotiriou, PhD, Karolinska Institutet, Stockholm, Sweden
521. Blow Spinning deposition of silicon nitride and metalized nanomaterial for multifunctional wound healing applications, Femi Alakija, David Mills, Louisiana Tech University, Ruston, LA, USA
522. Intrapolymeric Catalysis of Nitric Oxide Release via a Metal-Organic Framework for Potent Antimicrobial Materials, Mark Garren1, Patrick Maffe1, Alyssa Melvin2, Lauren Griffin1, Sarah Wilson1, Megan Douglass, PhD1, Melissa Reynolds, PhD2, Hitesh Handa, PhD1, 1University of Georgia, College of Engineering, Athens, GA, USA, 2Colorado State University, Ft. Collins, CO, USA
523. Nitric Oxide Releasing Catheter Disinfection Device, Manjyot Kaur Chug1, Elizabeth Brisbois, 1University of Georgia, Athens, GA, USA
Anti-Thrombogenic Coatings/Biomaterials for Vascular Applications
524. Antagonistic effect of magnesium hydroxide nanoparticle on vascular endothelial activation induced by acidic PLGA degradation product, Kyoung-Won Ko, PhD, Dong Keun Han, PhD, CHA University, Seongnam-si, Republic of Korea
525. Improved Damage Resistance of Hydrogel Coatings Based on Interpenetrating Networks, Megan Wancura, Abbey Nkansah, Andrew Robinson, Elizabeth Cosgriff-Hernandez, PhD, University of Texas at Austin, Austin, TX, USA
526. Endothelial Colony Forming Cell Rolling and Adhesion Supported by Peptide Combinations, Yuan Tian, PhD, Wen Seeto, PhD, Elizabeth Lipke, PhD, Auburn University, Auburn, AL, USA
Biodegradable and Bio-reactive Smart Materials
527. Bacteria-Responsive Electrospun Fibers for Wound Infection Surveillance, Avery Gunderson, Maryam Ramenzani, Mary Beth Browning Monroe, Syracuse University, Syracuse, NY, USA
528. Shape Memory Polymers with Phenolic Acid-Based Antioxidant Properties, Changling Du, David Fikhman, Mary Beth Monroe, BioInspired Syracuse, Syracuse, NY, USA
529. Genipin-Crosslinked Gelatin Bioplastics for Edible Origami Actuators, Spencer Matonis, Bozhong Zhuang, Siya Scindia, Christopher Bettinger, PhD, Carnegie Mellon University, Pittsburgh, PA, USA
530. Synergistically Enhanced Functions of Superelastic Nitinol and Biodegradable Metals to Develop A Growing Percutaneous Heart Valve Frame for The Pediatric Patients, Moataz Elsisy1, Seungil Kim, PhD2,3, Sang-Ho Ye, PhD2,3, Kaitlin Chung1, William Wagner, PhD1,2,3, Youngjae Chun, PhD1,3, 1University of Pittsburgh, Pittsburgh, PA, USA, 2Department of Surgery, Pittsburgh, PA, USA, 3McGowan Institute for Regenerative Medicine, Pittsburgh, PA, USA
531. Preparation and characterization of biodegradable metal particle incorporated polycaprolactone nanofibers, Dekonti Devies, Narayan Bhattarai, Felix Tettey, North Carolina A&T State University, Greensboro, NC, USA
532. Amphiphilic PEG-4 Arm Maleimidea*"Pluronic-Dithiol Click-Linked Hydrogels, Stephen Linderman, MD, PhD1,2, Andres Garcia, PhD2, 1Emory University, Atlanta, GA, USA, 2Georgia Institute of Technology, Atlanta, GA, USA
534. Development of an Effective Antibacterial Modification for the Novel Injectable Composite Based on Hydroxyapatite and Cross-linked Gelatin with Potential for Application as an Adhesive for Implants Fixation, Marcin Wekwejt, PhD1, Magda Rosciszewska, MSc1, Malgorzata Nadolska, MSc1, Anna Palubicka, PhD2, Anna Ronowska, DSc3, Aleksandra Mielewczyk-Gryn, DSc1, Michal Bartmanski, PhD1, 1Gdansk University of Technology, Gdansk, Poland, 2Specialist Hospital in Koscierzyna, Koscierzyna, Poland, 3Medical University of Gdansk, Gdansk, Poland
BioInterfaces (SIG)
535. Shape Memory Polymer Foams with Tunable Interconnectivity Using Off-the-Shelf Foaming Components, Natalie Petryk, BS, Grace Haas, Anand Vakil, Mary Beth Monroe, PhD, Syracuse University, Syracuse, NY, USA
536. Electrochemical Techniques to Investigate Adsorption and Desorption Behavior of Fibrinogen on a Gold Surface, Gowtham Mohanraj, BE, Caelen Clark, Behnoosh Sattari Baboukani, Prathima Nalam, Mark Ehrensberger, University at Buffalo, Buffalo, NY, USA
Biomaterial Innovations for Women's and Children's Health: Translation from Idea to the Clinic
537. Low-Cost Ethyl Cellulose Injector for Cervical Pre-Cancer Ablation in Low and Middle Income Countries, David Garvey, BS1,2, Jenna Mueller, PhD1,3,4, Kevin Aroom, MS, PE1,2, Martha Wang, PhD1,2, 1University of Maryland, College Park, College Park, MD, USA, 2Robert E. Fischell Institute for Biomedical Devices, College Park, MD, USA, 3Department of OB-GYN & Reproductive Science at the University of Maryland School of Medicine, Baltimore, MD, USA, 4Program in Oncology at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA
538. Physical Properties of Electrospun Gelatin Networks Compared with Fetal Membrane Tissues, Michelle Oyen, PhD1,2, Mackenzie Wheeler2, 1Washington University in St. Louis, St. Louis, MO, USA, 2East Carolina University, Greenville, NC, USA
Biomaterial Systems for Immunomodulation & Immune Cell Therapy
539. DNA-based Polyvalent Antibody Mimic for Immunoengineering of Natural Killer Cells, Kyungsene Lee1, Peng Shi2, Xuelin Wang1, Brandon Davis1, James Coyne1, Yong Wang1, 1The Pennsylvania State University, State College, PA, USA, 2Changchun Institute of Applied Chemistry, Changchun, China
540. Mapping the intrinsic immunomodulatory profiles of polymer microneedle arrays, Shrey Shah1, Robert Oakes, PhD1,2, Senta Kapnick, PhD1, Christopher Jewell, PhD1,2,3, 1Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA, 2Department of Veterans Affairs, Baltimore, MD, USA, 3Robert E. Fischell Institute for Biomedical Devices, College Park, MD, USA
541. Microrheological properties of mice skin draining and mesenteric lymph nodes using live tissue slicing, Ann Ramirez, Brooke Merwitz, Dalia Kassas, Katharina Maisel, University of Maryland, College Park, College Park, MD, USA
542. Induction of Regulatory T Cell Phenotypes for Applications in Multiple Sclerosis, Rebeca Stiepel1, Sean Simpson, PhD1, Christopher Genito, PhD2, Eric Bachelder, PhD1, Kristy Ainslie, PhD1,2,3, 1Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 3University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, USA
543. Microfluidic Nanoparticle Physicochemical Property Effects on Inflammatory Cytokine Modulation in Macrophages, Jacob Shaw1, Nhu Truong2, Sheneil Black2, Ryan Pearson, Ph.D.2,3, 1University of Maryland School of Medicine, Baltimore, MD, USA, 2University of Maryland School of Pharmacy, Baltimore, MD, USA, 3Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA
544. Cytokine Supplementation for T Lymphocyte Expansion Using Magnetic Mineral-Coated Microparticles, Hannah Martin, Joshua Choe, Iris Baurceanu, William Murphy, PhD, University of Wisconsin-Madison, Madison, WI, USA
545. Augmentation of Oral Immunotherapy with Tolerance-induce Nanoparticles, Rian Harriman, Nicolas Radoc, Vartika Kumar, Hamilton Kakwere, Jamal Lewis, UC Davis, Davis, CA, USA
546. Engineered Textiles as Substrates for Cell Selection and Activation, Molly Kaufman, Benjamin Roadarmel, Brian Ginn, Ph.D., Jeremy Harris, Ph.D., Secant Group, LLC., Telford, PA, USA
547. A Microparticle Strategy to Induce Tolerogenic Dendritic Cells for Treatment of Rheumatoid Arthritis, Allen Tu1, Riley Allen, PhD1, Siba Raychaudhuri, MD2, Jamal Lewis, PhD1, 1University of California, Davis, Davis, CA, USA, 2UC Davis Health, Sacramento, CA, USA
548. Elucidating the relationship between mechanosensing and metabolism in T cells, Paula Schultheiss, Daizong Sun, Lance Kam, PhD, Columbia University, New York, NY, USA
549. Assessing Efficiency of mRNA Lipid Nanoparticle Formulations Using Fluorescence Microscopy, Matthew Rosenwasser1,2, Derfogail Delcassian, PhD1, 1UC Berkeley, Berkeley, CA, USA, 2UCSF, San Francisco, CA, USA
550. Dexamethasone loaded PLGA-microparticles intracellularly induce an anti-fibrotic, anti-inflammatory macrophage phenotype for cell therapy applications, Tina Tylek, Kara Spiller, PhD, Drexel University, Philadelphia, PA, USA
Biomaterial-Based In Vitro Cancer/Tumor Models for Drug Screening and Diagnostics
551. 3D Bioprinted Spheroidal Droplets with Cardiomyocytes and Cardiac Fibroblasts for Drug Cytotoxicity Testing, Raven El Khoury1,2, Naveen Nagiah, PhD1,2, Binata Joddar, PhD1,2, 1University of Texas at El Paso (UTEP), El Paso, TX, USA, 2INSPIRED MATERIALS & STEM-CELL BASED TISSUE ENGINEERING LABORATORY, El Paso, TX, USA
552. Synergistic Drug Combinations for a Precision Medicine Approach to Interstitial Glioblastoma Therapy, Ryan Woodring, BS1, Elizabeth Graham-Gurysh, PhD1, Kristy Ainslie, PhD1,2, Eric Bachelder, PhD1, Shawn Hingtgen, PhD1, Ananya Murthy, PhD1, Kathryn Moore, PhD2, 1University of North Carolina, Chapel Hill, NC, USA, 2North Carolina State University, Raleigh, NC, USA
553. Modeling Cancer Metastasis Using a Bioorthogonally Integrated Hydrogel Platform, Mugdha Pol1, Hanyuan Gao, Joseph Fox, Xinqiao Jia, 1University of Delaware, Newark, DE, USA
554. Gelatin Methacryloyl Model of Glioblastoma to Benchmark Patterns of Invasion and Chemotherapeutic Resistance, Viktoriia Kriuchkovskaia1, Brendan Harley, PhD1, Rebecca Riggins, PhD2, 1University of Illinois Urbana-Champaign, Urbana, IL, USA, 2Georgetown University, Washington, DC, USA
555. Examining Breast Cancer Response to Metformin Using Tissue-Engineered in vitro Testbeds, Emory Gregory, Inah Gu, Casey Atwood, MS, RD, LD, Luis Pinzon-Herrera, Jorge Almodovar, PhD, Sun Ok Lee, PhD, Young Hye Song, PhD, University of Arkansas, Fayetteville, AR, USA
556. A Biomimetic Hyaluronic Acid Hydrogel Induces Mass Dormancy in Brain Metastatic Breast Cancer Cell Spheroids, Raghu Vamsi Kondapaneni, Grad Student1, Shreyas. S Rao, Professor1, Lalita. A Shevde, Professor2, 1The University of Alabama, Tuscaloosa, AL, USA, 2University of Alabama at Birmingham, Birmingham, AL, USA
557. Cytotoxicity of Lithium phenyl-2,4,6-trimethylbenzoylphosphinate on Panc-1 cells in Methacrylated Type I Collagen, Jessica Netto, Catherine Whittington, PhD, Worcester Polytechnic Institute, Worcester, MA, USA
558. A 3D Breast Tumor Model to Idnentify Treatments Against Cancer Cell Invasion, Jacob Heiss, Nina Treacher, Hossein Tavana, PhD, The University of Akron, Akron, OH, USA
559. Design of a Three-Dimensional (3D) Adipose-laden Hydrogel Model to Study Breast Cancer Metastasis, Ah Joung Yu, Cheryl Gomillion, PhD, University of Georgia, Athens, GA, USA
560. Promoting and Assessing Cell Capture in a Wicking Fiber Cancer Predictive Tool, Timothy Burg, PhD, Kelsey Collins, Karen Burg, PhD, University of Georgia, Athens, GA, USA
561. Using Photo-polymerizable Collagen to Characterize Panc-1 Behavior Under Simulated Fibrotic Conditions In vitro, Athenia Jones, Mathiew Daniels-Diehl, Catherine Whittington, PhD, Worcester Polytechnic Institute, Worcester, MA, USA
562. A Gravity-Driven Multi Micro Physiological System to Study Tissue Responses to Cancer Therapeutics, Pouria Rafsanjani Nejad, MSc, Hossein Tavana, PE, PhD, University of Akron, Akron, OH, USA
Biomaterials & Medical Products Commercialization
563. Effects of Commercially-Available Catalysts on Shape Memory Polymer Foam Properties, Grace Haas, Natalie Petryk, Anand Vakil, Mary Beth Monroe, Syracuse University, Syracuse, NY, USA
564. Development of a Novel Carrier Protein for Polyclonal Antibody Production, Jessica Miller, Ph.D., Gregory Krug, Bill Bucher, Robert Bayer, Ph.D, Edward Sosienski, Lampire Biological Laboratories, Pipersville, PA, USA
565. Sleep Good Hood System: Reducing Sleep Deprivation In Hospital Settings With Light Attenuation, Mauricio Defngin, Ainul Wadhihah Abdul Rahim, Martha Wang, PhD, John Rzasa, Kevin Aroom, Robert E. Fischell Institute for Biomedical Devices, College Park, MD, USA
567. Masking and Attenuating Noise Within Hospital Settings: Sleep Good Hood System, Ainul Wadhihah Abdul Rahim, Mauricio Defngin, Martha Wang, PhD, John Rzasa, PhD, Kevin Aroom, Robert E. Fischell Institute For Biomedical Devices, College Park, MD, USA
Biomaterials Education
568. Developing Hands-On Biomaterials Education Modules Using Alginate Hydrogels, Victoria Muir, Kayla Brown, Julio Rivera De Jesus, Jason Burdick, University of Pennsylvania, Philadelphia, PA, USA
569. Characterizing Properties of Thiol-ene Crosslinked Hyaluronic Acid Hydrogels for Meniscus Tissue Engineering, Kayla Castillo, Philip Elrod, MBA, Jennifer Robinson, PhD, Stevin Gehrke, PhD, Joseph Scalet, Alan Allgeier, PhD, Murillo Toledo Suekuni, Elizabeth Aikman, University of Kansas, Lawrence, KS, USA
Biomaterials for Organoids
570. Fast Stress-Relaxing Double Network Hydrogels for Induced Pluripotent Stem Cell (iPSC) Culture, Nathan Dimmitt1, Matthew Arkenberg, MS2, Chien-Chi Lin, PhD1, 1Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA, 2Purdue University, West Lafayette, IN, USA
571. Isolation, Culture and Functionality Studies of 3D Colonoids Using the Original Niches, Zahra Davoudi1, Albert Jergens, Michael Wannemuehler, Qun Wang, 1Iowa State University, Ames, IA, USA
572. Formation and Characterization of Colon Tumor Organoids from Primary Cells, Astha Lamichhane, Hossein Tavana, PhD, University of Akron, Akron, OH, USA
573. Subcellular Spatial Transcriptional Profiling of Mesenchymal Stem Cells in Hydrogel by Multiplexed RNA Imaging, Zhou Fang, Ryan Abramowitz, Sungwoong Kim, Thomas Hu, Mayar Allam, Ankur Singh, Ahmet Coskun, Georgia Institute of Technology, Atlanta, GA, USA
575. Synthesis and characterization of elastin-like polypeptide and RGD copolymers and their effect on spheroid formation, Sheetal Chowdhury, B.S. in Biomedical Engineering, Courtney Cates, BS, MS, Gene Bidwell, PhD, Abelardo Medina, MD, Amol Janorkar, PhD, University of Mississippi Medical Center, Jackson, MS, USA
576. Tuning Engineered Hydrogel Matrix Composition for Salivary Gland Tissue Mimetic Culture, Jared Mereness, PhD1, Lindsay Piraino1, Lisa DeLouise, PhD1, Catherine Ovitt, PhD2, Danielle Benoit, PhD1, 1University of Rochester, Rochester, NY, USA, 2University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Biomaterials for Pancreatic Islet Replacement and Immune Tolerance in T1D
577. In Vivo High-throughput Screening of Immunomodulatory Biomaterials using Cellular Barcoding for Human Islets Transplantation in Immunocompetent Type 1 Diabetic Mice Models, Boram Kim1, Sudip Mukherjee1, Lauren Cheng1, Michael Doerfert1, Jiaming Li1, Peter Rios2, Jose Oberholzer2, David Zhang1, Omid Veiseh1, 1Rice University, Houston, TX, USA, 2CellTrans, Chicago, IL, USA
578. Hydrogel System for Improved Cell Graft Viability and Function in Treating Type 1 Diabetes, Victor Quiroz, Jr., Yuanjia Wang, Sarah Neshat, Stephany Tzeng, PhD, Joshua Doloff, PhD, Johns Hopkins University, Baltimore, MD, USA
579. Recapitulating Lymph Node Stromal Cell Reticula in Type 1 Diabetes Using Gelatin Scaffolds, Leonor Teles1,2, Zachary Wilkes1,2, Flavia Zisi Tegou1,2, Diana Velluto, PhD2, Edward Dauer, MD1, Fotios Andreopoulos, PhD1, Remi Creusot, PhD3,4, Alice Tomei, PhD1,2, 1University of Miami, Coral Gables, FL, USA, 2Diabetes Research Institute, Miami, FL, USA, 3Columbia Center for Translational Immunology, New York, NY, USA, 4Naomi Berrie Diabetes Center, New York, NY, USA
580. Changes in Peri-Islet Extracellular Matrix Stiffness Regulate Insulin Secretion via Mechanotransduction Signaling, Chelsea Garcia, Meghana Murthy, Keifer Holcomb, Nikki Farnsworth, PhD, Colorado School of Mines, Golden, CO, USA
581. Exploring the Synergistic Connection between Glucose Metabolism and Mechanosensitivity in Macrophage Function, Courtney Johnson1,2, Helim Aranda-Espinoza, PhD1, John Fisher, PhD1,2, 1University of Maryland, College Park, MD, USA, 2Center for Engineering Complex Tissues, College Park, MD, USA
582. Laminin Interactions with the Islet in a 3D Reverse Thermal Gel Scaffold Protect Against Cytokine- Mediated I2-Cell Death, Meghana Hosahalli Shivananda Murthy, MS, Nikki Farnsworth, PhD, Colorado School of Mines, Golden, CO, USA
583. Optimization of Oxygen Transport within Islet Macroencapsulation Device via Finite Element Modeling and MRI Oximetry, Amy Emerson, Yuka Sugamura, Chishiba Chilimba, Vikram Kodibagkar, Jessica Weaver, Arizona State University, Tempe, AZ, USA
584. Methacrylic Acid-based Synthetic Hydrogel Enhances Immunomodulation by Tolerogenic Dendritic Cells, Sean Kinney, Benedikt Licht, Ilana Talior-Volodarsky, Michael Sefton, University of Toronto, Toronto, ON, Canada
585. Waffle-inspired micropatterned macrodevice for spatially controlled distribution and vascularization of encapsulated cellular therapeutics, Yicong Zuo, PhD, Yang Chen, Chi Pham, Nam Tran, Dang Nguyen, Tram Dang, PhD, Nanyang Technological University, Singapore, Singapore
Biomaterials for Regenerative Engineering
586. Mineralized Collagen Scaffold Pore Structure Enhances Immunomodulatory Potential of Mesenchymal Stem Cells, Vasiliki Kolliopoulos, Brendan Harley, PhD, University of Illinois at Urbana-Champaign, Urbana, IL, USA
587. Stem cell proliferation improved with low endotoxin and low molecular weight gelatin, Jos Olijve1, Elien Gevaert, PhD, 1Rousselot-Biomedical, Ghent, Belgium
588. Towards Regeneration of the Cranial Suture: Pore Curvature Regulates Mesenchymal Stem Cell Fate in Macroporous Tissue Engineering Scaffolds, W Benton Swanson, Seth Woodbury, Maiko Omi, Hwa Kyung Nam, Peter Ma, Nan Hatch, Yuji Mishina, University of Michigan, Ann Arbor, MI, USA
589. Electrical stimulation through PPy/HE/PLLA conductive membrane improved wound healing properties of diabetic fibroblasts, Atieh Abedin do, Ze Zhang, Mahmoud Rouabhia, Universite Laval, Quebec, QC, Canada
590. Matrix Degradability Contributes to the Development of Salivary Gland Progenitor Cells with Secretory Functions, Apoorva Metkari, Eric Fowler, PhD, Xinqiao Jia, PhD, University of Delaware, Newark, DE, USA
591. Pre-vascularized, 3D Printed Scaffolds for Optimization of Cell-based Therapies, Robert Accolla1, Jia-pu Liang, PhD1, Amberlyn Simmons1, Taylor Lansberry1, Madison Deller1, Cherie Stabler, PhD1,2, 1University of Florida, Gainesville, FL, USA, 2University of Florida Diabetes Institute, Gainesville, FL, USA
592. Functional Biomaterials to Control the Immunosuppressive Capacity of Human Mesenchymal Stromal Cells, David Castilla, PhD1, Logan Morton1, Mahsa Haseli2, Jorge Almodovar, PhD2, Adrianne Rosales, PhD1, 1The University of Texas at Austin, Austin, TX, USA, 2University of Arkansas, Fayetteville, AR, USA
593. Biodegradable hybrid scaffolds with PDRN/BMP2 nanocomplex using human fetal derived mesenchymal stem cells for bone regeneration, Da-Seul Kim1,2, Jun-Kyu Lee1, Dong Keun Han1, 1CHA university, Seongnam-si, Republic of Korea, 2Chung-Ang University, Seoul, Republic of Korea
594. Enhancing the Mechanical and Molecular Properties of Polycaprolactone Nanofibers with Heat-Setting, Matthew Flamini, BS1, Thamires Lima, PhD2, Kerri McBride1, Vincent Beachley, PhD1, 1Rowan University, Glassboro, NJ, USA, 2Drexel University, Philadelphia, PA, USA
595. Head-to-Head Comparison of Thiol-Ene and Tetrazine Click Annealing Chemistry on Scaffold Properties, Sarea Recalde Phillips, Alisa Isaac, Daniel Alge, PhD, Texas A&M University, College Station, TX, USA
596. Controlling Scaffold Conductivity and Pore Size to Direct Myogenic Cell Alignment and Differentiation, Ivan Basurto, Samir Muhammad, George Christ, Steven Caliari, University of Virginia, Charlottesville, VA, USA
597. 3D Printing of Highly Viscous Cellulose Nanofiber-enhanced Gelatin Methacryloyl for Tissue Engineering, Jiahui Lai, Min Wang, The University of Hong Kong, Hong Kong, Hong Kong
598. Spontaneous Alignment of Myotubes through Satellite Cell Migration, Lauren Mehanna, Charlotte Peterson, PhD, Brad Berron, PhD, University of Kentucky, Lexington, KY, USA
599. Pneumatic-drive Fiber-Robot Scaffold for Three-Dimensional Dynamic Tissue Culture, Shane Harrington1, Muh Amdadul Hoque, Xiaomeng Fang, PhD, Jessica Gluck, PhD, 1North Carolina State University, Raleigh, NC, USA
601. Engineering Hyaluronic Acid Hydrogels with Design of Experiments for Controlled Protein Delivery, Veronica Spaulding, MSc, Ireland Johnson, Marian Hettiaratchi, PhD, University of Oregon, Eugene, OR, USA
602. Novel 3D Hydrogel System Improves the Retainment of Viable MSC Populations Overtime, Jacob Hodge, MS1,2, Jennifer Robinson, PhD1, Adam Mellott, PhD2, 1University of Kansas, Lawrence, KS, USA, 2University of Kansas Medical Center, Kansas City, KS, USA
603. 3D Printed Highly Elastic Scaffolds Reinforced by Electrospun Fibers for Uterine Tissue Engineering, Shangsi Chen, Jizhuo Chen, Liwu Zheng, Min Wang, The University of Hong Kong, Hong Kong, China
604. Protein-based Flexible Thermal Conductive Materials for Biomedical Applications, Xiao Hu, PhD, Rowan University, Glassboro, NJ, USA
605. Design of Collagen-Like Proteins to Study Structure-Function Relationships in Vascular Ehlers-Danlos Syndrome, Sonal Gahlawat, David Shreiber, Rutgers, The State University of New Jersey, Piscataway, NJ, USA
606. Next-generation Peptide-Functionalized Gelatin Hydrogels for Neovascularization, Corinne Curry, Kate Mlouk, Lucas Mowry, Riya Patel, Hayden Paige, Jeffrey Schmeckpeper, MD, Ethan Lippmann, PhD, Vanderbilt University, Nashville, TN, USA
607. Formation of Vascular Networks in a PEGylated Fibrin Hydrogel Increases Proliferation of Cardiomyocytes, Staunton Golding, Jeffrey Jacot, PhD1, Ethan Vanderslice1, 1University of Colorado Anschutz, Denver, CO, USA
608. Increasing Human Mesenchymal Stem Cell Attachment to poly(glycerol dodecanedioate), a Biodegradable Shape Memory Polymer, Harsha Ramaraju, PhD, Elisa Garcia-Gomez, Annabel McAtee, Adam Verga, Scott Hollister, PhD, Georgia Institute of Technology, Atlanta, GA, USA
609. Design and Cytocompatibility of Hyaluronic Acid Hydrogels for Bone Regeneration, Ireland Johnson, Veronica Spaulding, Andres Guerrero, Marian Hettiaratchi, University of Oregon, Eugene, OR, USA
610. Gelatin-based Microcarriers Fabricated as Injectable Bone Scaffolds for Mesenchymal Stem Cell Osteogenesis, Chukwuma Nweke, Jan Stegemann, University of Michigan, Ann Arbor, MI, USA
611. Junction Functionality-Dependent Stiffness and Solute Transport in Biocompatible Hydrogels Biomaterials for Regenerative Engineering, Nathan Richbourg, Nicholas Peppas, The University of Texas, Austin, TX, USA
612. LIPUS-Derived Mechanical Stimulation of Collagen Hydrogels for Bone Repair, Fayekah Assanah, PhD1, Hanna Anderson1, Kevin Grassie1, Yusuf Khan, PhD2, 1University of Connecticut, Storrs, CT, USA, 2UCONN Health, Farmington, CT, USA
613. Hierarchically porous Slit3-releasing Composite Scaffold for Bone Tissue Engineering, Ali Alshami, Abdulrahman Al-Shami, University of North Dakota, Grand Forks, ND, USA
614. In Vivo Evaluation of Cell-Releasing Hydrogel in 3D-Printed PolyHIPE Scaffolds, Dana Jenkins, Prachi Dhavalikar, PhD, Aparajith Kannapiran, Sahana Balaji, Elizabeth Cosgriff-Hernandez, PhD, The University of Texas at Austin, Austin, TX, USA
615. Magnetic Nanoparticle Drug Delivery System for the Promotion of Vascularization in Tissue Regeneration, Eric Brey, PhD, Gabriela Romero Uribe, Jacob Brown, B.S. Biomedical Engineering, UTSA, San Antonio, TX, USA
616. Chemically Defined Plant Leaf-derived Biomaterials for Muscle Tissue Engineering, Junsu Yun, Masatoshi Suzuki, PhD, Padma Gopalan, PhD, William Murphy, PhD, University of Wisconsin-Madison, Madison, WI, USA
617. Mesenchymal Stem Cell Delivery via Topographically Tenoinductive Collagen Biotextile Enhances Regeneration of Segmental Tendon Defects, Phillip McClellan, PhD1, Jason Ina, MD2, Derrick Knapik, MD2, Ilaha Isali, MD1, Alexis Valente1, Yujing Wen1, Cindy Wu1, Ruiqi Wen1, James Anderson, MD, PhD1, Robert Gillespie, MD2, Ozan Akkus, PhD1, 1Case Western Reserve University, Cleveland, OH, USA, 2University Hospitals Cleveland Medical Center, Cleveland, OH, USA
618. In situ forming and nitric oxide releasing gelatin-based hydrogels for tissue engineering, Simin Lee, Dieu Linh Tran, Thi Phuong Le, Ki Dong Park, Ajou University, Suwon, Republic of Korea
619. Metallized Clay Nanoparticles for Tissue Regeneration, Abdul-Razak Masoud, David Mills, Louisiana Tech UNiversity, Ruston, LA, USA
620. Characterization of norbornene-modified cellulose electrospun fibers in different solvent systems for biomedical applications, Quintin Norris, Kevin Tindell, Matthew Green, Julianne Holloway, Arizona State University, Tempe, AZ, USA
621. Wound healing analysis of human and porcine placental membranes in an in vivo rat skin defect model, Alex Bryan, Matthew Atwill, Andrew Blass Watson, Samantha Hall, Mallesh Kurakula, PhD, Joel Bumgardner, PhD, The University of Memphis, Memphis, TN, USA
622. Wnt7a-Releasing Hydrogel Inhibits Adipogenesis of Skeletal Muscle Mesenchymal Stromal Cells, Woojin Han, PhD, Chengcheng Fu, Icahn School of Medicine at Mount Sinai, New York, NY, USA
623. Accelerating the Pathway from Bench to Bedside: The Printability of Human Dental Pulp Stem Cells with Physiological Relevance, Satish Alapati, PhD, DDS1, Taneka Jones, PhD, 1University of Illinois Chicago, Chicago, IL, USA
624. Effect of ellagic acid on human dermal fibroblasts elastogenesis, Nasim Nosoudi, Chloe Duckworth, Jada stutts, Marshall university, Huntington, WV, USA
Biomaterials for Sustainable Food Systems
625. Decellularized Mycelium as An Edible 3D Scaffold for Cultured Insect Fat, Sophia Letcher, BA, Natalie Rubio, PhD, Adham Ali, Olivia Calkins, Aidan McCreary, David Kaplan, PhD, Tufts University, Medford, MA, USA
626. Dual-Crosslinked Porous Alginate Scaffolds for use in Cultured Meat Production, Rachael Floreani, Irfan Tahir, University of Vermont, Burlington, VT, USA
627. Cultured Meat with Tunable Fat Content: Scaffolds for Multicomponent Tissue with Myocytes and Adipocytes, Nora Kawecki, M.S., Sam Norris, PhD, Amy Rowat, PhD, University of California, Los Angeles, Los Angeles, CA, USA
Biomaterials for Trauma, Surgery and Wound Healing Applications *BTI*
628. Solution Blow Spinning of Biodegradable Tissue Adhesives for Applications in Surgery, Metecan Erdi, B.S., John Daristotle, Ph.D., Lung Lau, M.D., Shadden Zaki, B.S., Priya Srinivasan, Ph.D., Omar Ayyub, Ph.D., Joseph Hunter, M.S., Albert Djoum, Jr., B.S., Xiaofang Wu, Ph.D., Mousumi Basu, B.S., Manogna Balabhadrapatruni, M.S., Massi Djouini, B.S., Anthony Sandler, M.D., Peter Kofinas, Ph.D.
629. Fabrication of a scaffold from novel protein-based electrospun yarn for skin tissue regeneration, Daxian Zha, North Carolina State University, Raleigh, NC, USA
630. Expandable Nanofiber Foams for Management of Junctional Hemorrhage, Jingwei Xie, Johnson John, Mark Carlson, University of Nebraska Medical Center, Omaha, NE, USA
631. Optimization of silk fibroin nanoparticles for encapsulation of piscine hemoglobin: A novel oxygen delivery system, Marisa Pacheco, Jostin Armada, Marina Fernandez-Campa, Bruce Spiess, M.D., Whitney Stoppel, PhD, University of Florida, Gainesville, FL, USA
632. Evaluating the Efficacy of a Multicomponent Wound Dressing for Simultaneous Antibacterial Activity and Moisture Management in an In-Vitro Wound Model, Elizabeth Gianino, Jordon Gilmore, PhD, Clemson University, Clemson, SC, USA
633. Hyperfibrinolysis Drives Mechanical Instabilities In Trauma Induced Coagulopathy, Andrew Gosselin, Valerie Tutwiler, PhD, Rutgers, The State University of New Jersey, Piscataway, NJ, USA
634. Synthetic and Characterization of Carboxymethyl Cellulose-based Hydrogel Coating to Potentially Prevent Post-Surgical Adhesions, Jiahui Chen1, King Martin, Professor1,2, 1North Carolina State University, Raleigh, NC, USA, 2Donghua University, Shanghai, China
635. Laser assisted barbed sutures for wound closures in plastic surgeries, Karuna Nambi Gowri1, Roger Narayan1, Phillip McClellan2, Gregory Ruff1, Martin King1, 1Wilson College of Textiles, NC State University, Raleigh, NC, USA, 2Case Western Reserve University, Cleveland, OH, USA
Biomaterials in Engineering the Tumor Immune Microenvironment
636. Succinate based biomaterials modify immune system and reduce tumour growth in aging immunocompetent mice, Sahil Inamdar1, Joslyn Mangal, Abhirami Suresh, Nathan Ng, Alison Sundem, Marion Curtis, Abhinav Acharya, 1arizona state university, tempe, AZ, USA
637. Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy, Li Tang, Kewen Lei, Armand Kurum, Institute of Bioengineering, Ecole polytechnique federale de Lausanne (EPFL), Lausanne, Switzerland,, Lausanne, Switzerland
Biomaterial-Tissue Interaction (SIG)
638. Investigation of Aberrant Cellular Changes with the Nanoplastics Exposure in Perfusion Cell Culture System, Samantha Yee, Ji Young Choi, John Fisher, University of Maryland, College Park, College Park, MD, USA
639. Polyurethane-based mechanically matched, angiogenic precision porous long-lasting elastomers (PUBMAPLE) towards in situ vascular engineering: a discussion on foreign body capsule assessment, Le Zhen, PhD, Sharon Creason, Felix Simonovsky, Jessica Snyder, Sarah Lindhartsen, Marvin Mecwan, Brian Johnson, Jonathan Himmelfarb, Buddy Ratner, University of Washington, Seattle, WA, USA
640. A Microfluidic Fibrosis-On-a-Chip Model to Study Biomaterial-Immune Interactions, Parinaz Fathi, PhD, Paniz Rezvan Sangsari, Andrea Lucia Alfonso, Matthew Wolf, PhD, Nicole Morgan, Kaitlyn Sadtler, PhD, National Institutes of Health, Bethesda, MD, USA
641. Influence of PCL Concentration and Solvent on Dimensions and Morphology of Electrosprayed Particles, Laura Alberto, Lohitha Kalluri, Yuanyuan Duan, University of Mississippi Medical Center, Jackson, MS, USA
642. Biomimetic, Cell-Membrane Wrapping of Nanoparticles Reduces Protein Adsorption, Eric Sterin, Jenna Harris, Emily Day, University of Delaware, Newark, DE, USA
643. Quantifying Non-Specific Peptide Degradation in Biomaterials, Eugene Pashuck, PhD, Samuel Rozans, Anna Edmundson, Liliana Nino, Lehigh University, Bethlehem, PA, USA
644. Carcinogenic Threat of Elastin-Rich Surgical Devices - A Review, Subramanian Gunasekaran, PhD, Encoll Corp, Fremont, CA, USA
645. In Situ Surface Modification of Emulsion Templated Bone Grafts with Hydroxyapatite Nanoparticles Improves Cell Adhesion, Prachi Dhavalikar, PhD1, Karim Salhadar1, Natalie Rosen2, Aparajith Kannapiran1, Michael Silverstein, PhD2, Elizabeth Cosgriff-Hernandez, PhD1, Dana Jenkins Jenkins1, 1The University of Texas at Austin, Austin, TX, USA, 2Technion*Israel Institute of Technology, Haifa, Israel
647. Chitosan, PLA, and PCL Composite Material for Biomedical Applications, Ali Alshami, Abdulrahman Al-Shami, University of North Dakota, Grand Forks, ND, USA
648. In Vitro Evaluation of the Potential Anti-inflammatory Effect of Raspberry Ketone on RAW 264.7 cells for Guided Bone Regeneration, Samarth Vedante, Joel Bumgardner, PhD, University of Memphis, Memphis, TN, USA
Biomimetic Hydrogels for Drug Delivery and Tissue Engineering Applications
651. Secretome-loaded Plasma-alginate Composite (PAC) Gels to Treat of Deep Partial-thickness Burn Injuries in a Porcine Burn Injury Model, Marc Thompson, PhD, Kameel Zuniga, PhD, Lucy Shaffer, Michelle Holik, Carole Nail, Logan Leatherman, Robert Christy, PhD, Shanmugasundaram Natesan, US Army Institute of Surgical Research, San Antonio, TX, USA
652. Enhanced tissue adhesiveness of poly(ethylene glycol) based hydrogels via enzymatic crosslinking reaction, Simin Lee, Thi Phuong Le, Ki Dong Park, Ajou University, Suwon, Republic of Korea
Biophysical Strategies for Regulation of Cellular Microenvironments
653. The Effect of Substrate on the Mechanical State of the Cell, Elizabeth Byers, Gabrielle Hamner, Pennsylvania State University, State College, PA, USA
654. Controlling Mesenchyme Tissue Remodeling via Spatial Arrangement of Mechanical Constraint, Zhen Ma, Tackla Winston, Chao Chen, Teng Zhang, Syracuse University, Syracuse, NY, USA
655. Fabrication of cell-laden macroporous hydrogel scaffolds using sacrificial microparticles, James Gentry, Steven Caliari, PhD, University of Virginia, Charlottesville, VA, USA
656. Dynamic Light Scattering Microrheology for Soft and Living Materials, Pamela Cai1, Brad Krajina1, Michael Kratochvil1, Audrey Zhu1, Elizabeth Burgener1, Paul Bollyky1, Carlos Milla1, Matthew Webber2, Andrew Spakowitz1, Sarah Heilshorn1, 1Stanford University, Stanford, CA, USA, 2University of Notre Dame, Notre Dame, IN, USA
657. Designing a Microfluidic Model of a Lymphatic Vessel, Erik Vaughan, Ann Ramirez, Katharina Maisel, University of Maryland, College Park, College Park, MD, USA
658. Spatially Patterned Differentiation of Human Pluripotent Stem Cells via Morphogen Localization, Gyuhyung Jin, PhD1,2, Martha Floy1, Aaron Simmons1, Madeline Arthur1, Sean Palecek, PhD1, 1University of Wisconsin-Madison, Madison, WI, USA, 2Purdue University, West Lafayette, IN, USA
659. Trisomy 21 Alters Cardiomyocyte Response to Substrate Stiffness, Rachel Reeser, Rukshika Hewawasam, PhD, Chelsea Magin, PhD, Jeffrey Jacot, PhD, University of Colorado | Anschutz Medical Campus, Aurora, CO, USA
660. Magnetically Actuated Cancer Metastasis Model (MACMM), Awatef Alsheri, PhD1,2, Otto Wilson Jr, PhD1, Chris Raub, Ph.D.1, Xiaolong Luo, Ph.D.1, 1Catholic University, Washington, DC, USA, 2King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
661. Interpenetrating Collagen I:Fibrin Matrices Differentially Support Musculoskeletal Remodeling Over Time, Gennifer Chiou, Isaiah Arredondo, Joo Ong, PhD, Rena Bizios, PhD, Teja Guda, PhD, University of Texas at San Antonio, San Antonio, TX, USA
662. Hydrogel Thickness and Nanofiber Connectivity Influence Cell Alignment and Morphology in Hydrogel-Nanofiber Composites, Brandon Herb, Shrey Dalwadi, Nikolas Belanger, Vince Beachley, PhD, Sebastian Vega, PhD, Rowan University, Glassboro, NJ, USA
663. Biophysical regulation of articular chondrocyte phenotype, Ram Saraswat, Zachary Nix, Scott Wood, PhD, South Dakota School of Mines and Technology, Rapid City, SD, USA
664. Extensional strain induces long-range alignment of collagen fibers in a microfluidic channel, Adeel Ahmed, Mehran Mansouri, Indranil Joshi, Ann Byerley, Steven Day, PhD, Thomas Gaborski, PhD, Vinay Abhyankar, PhD, Rochester Institute of Technoloogy, Rochester, NY, USA
665. Microengineered Collagen Hydrogels with Spatial Gradations in the Fiber Alignment Landscape, Indranil Joshi, Adeel Ahmed, Mehran Mansouri, Ann Byerley, Thomas Gaborski, PhD, Steven Day, PhD, Vinay Abhyankar, PhD, Rochester Institute of Technology, Rochester, NY, USA
Bioprinting for Tissue Engineering: from Open Source to Commercial Platforms
667. Nanoengineered Methylcellulose bioinks via Tetrazine-Norbornene Click Chemistry, Min Hee Kim, PhD, Chien-Chi Lin, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA
668. Aggrecan-Functionalized Methacrylated Hyaluronic Acid Bioinks for Cartilage Regeneration, Robert Choe1,2, John Osborne1,2, Blake Kuzemchak1,2, Noah Eby1,2, John Fisher1,2, 1University of Maryland College Park, College Park, MD, USA, 2Center for Engineering Complex Tissues, College Park, MD, USA
669. 3D Hybrid Printed PCL/MEHA Scaffolds for Osteochondral Tissue Regeneration, Noah Eby1,2, Robert Choe1,2, Blake Kuzemchak1,2, John Osborne1,2, John Fisher1,2, 1University of Maryland, College Park, College Park, MD, USA, 2Center for Engineering Complex Tissues, College Park, MD, USA
671. Fabrication and Evaluation of 3D Printing Scaffolds Using Biodegradable Aliphatic Polycarbonate, Yun Bae Ji, Moon Suk Kim, Ajou University, Suwon, Republic of Korea
672. De Novo Design and Bioprinting of Vascular Trees for Modular Engineering of Organs, Melissa Torres, Ryan Mangulabnan, Howard Matthew, Wayne State University, Detroit, MI, USA
673. Achieving Complex Alignment in Tissue Engineering through 3D Bioprinting Pre-Aligned Microtissues, Caleb Vogt, Angela Panoskaltsis-Mortari, PhD, University of Minnesota - Twin Cities, Minneapolis, MN, USA
675. Finite Element Analysis of Patient-Specific 3D Printed Bone Graft for Vertical Alveolar Ridge Augmentation, Claudia Benito Alston1, Luis Solorio, PhD1, Nicanor Moldovan, PhD2, Clark Barco, DDS2, 1Purdue University, West Lafayette, IN, USA, 2Richard L Roudebush Va Medical Center, Indianapolis, IN, USA
676. The Balance of Parameters Required for Melt Electrowriting High-Quality Scaffolds, Paul Dalton1, Kelly O'Neill1, Biranche Tandon1, Simon Luposchainsky1, Ievgenii Liashenko1, Huaizhong Xu2, 1University of Oregon, Eugene, OR, USA, 2Kyoto Institute of Technology, Kyoto, Japan
677. Screen printing hydrogel constructs for fabricating high throughput in vitro models, Bryan Ibarra, MS, James Dolgin, Stephen Farias, PhD, Materic Group, Baltimore, MD, USA
Cardiovascular Biomanufacturing
678. Engineering Particle-based Gels for Vasculogenesis to Support Multicellular Tissue Structures, Natasha Claxton, Melissa Luse, Brant Isakson, PhD, Chris Highley, PhD, University of Virginia, Charlottesville, VA, USA
679. Stem Cell-Laden Microspheres as Building Blocks for Large Cardiac Tissue Production Through Secondary Encapsulation in Poly(ethylene glycol)-Fibrinogen, Justin Harvell, Mohammadjafar Hashemi, Elizabeth Lipke, PhD, Auburn University, Auburn, AL, USA
Cardiovascular Biomaterials (SIG)
680. Dendrimer-based Nanoparticles with Dual-Modality Imaging for Atherosclerosis, Huari Kou, Da Huang, Hu Yang, Missouri University of Science and Technology, Rolla, MO, USA
681. 'Designer' PDMS Cover Slips for Registration of Second Harmonic Generation and Atomic Force Microscopy Images., Adam Baker, BS, MS, Zhi Gao, PhD, Clemson University, Clemson, SC, USA
682. Analyzing Phenotype Changes during Coronary Bypass Graft Remodeling, Reece Fratus, Thomas Fair, Lucas Schmidt, PhD, Bruce Gao, PhD, Clemson University, Clemson, SC, USA
683. A Novel Dual Chamber Perfusion Stent Graft Using a Smart Nitinol and Highly Stretchable ePTFE to Isolate Blood Flow in Donation after Cardiac Death, Moataz Elsisy1, Bryan Tillman2, Lynn Chau1, Catherine Go3, Sung Kwon Cho1, Youngjae Chun1,4, 1University of Pittsburgh, Pittsburgh, PA, USA, 2The Ohio State University Wexner Medical Center, Columbus, OH, USA, 3University of Pittsburgh Medical Center, Pittsburgh, PA, USA, 4McGowan Institute for Regenerative Medicine, Pittsburgh, PA, USA
684. Medial Vascular Calcification Inhibition through the Wnt/I2-Catenin Pathway, Gabriella Hobbs, C. LaShan Simpson, PhD, Mississippi State University, Mississippi State, MS, USA
685. Investigating Organic Redox-active Crystals for Thrombotic Response, Drew Filchner1, Lichong Xu, Ph.D.2, Keren Zhou3, Aida Ebrahimi, Ph.D.3, Christopher Siedlecki, Ph.D.2, 1Bucknell University, Lewisburg, PA, USA, 2Pennsylvania State University College of Medicine, Hershey, PA, USA, 3The Pennsylvania State University, University Park, PA, USA
686. Biomimetic Proteoglycans Increase the Indentation Modulus of the Porcine Aortic Valve Leaflet Spongiosa Without Compromising Cross-Linking Stability, Mark Petrovic, Elizabeth Kahle, Lin Han, PhD, Michele Marcolongo, PhD, PE, Drexel University, Philadelphia, PA, USA
687. Hydrolytic stability and biocompatibility of injectable hydrogel electrodes for treatment of ventricular arrhythmias, Gabriel Rodriguez-Rivera, MS, PE1, Elizabeth Cosgriff-Hernandez, PhD1, Abbey Nkansah1, Alberto Maradiaga1, Manuel Rausch1, Allison Post2, Megan Wancura1, Mathews John2, Skylar Buchan2, Mehdi Razavi2, 1The University of Texas at Austin, Austin, TX, USA, 2Texas Heart Institute, Houston, TX, USA
Challenges for Total Joint Replacement Materials
688. The Effect of Cathodic Voltage-Controlled Electrical Stimulation on the Bone-Titanium Interface, Eric McDermott, PhD, Menachem Tobias, MS, Kyle Weeks, MS, Thomas Duquin, MD, Mark Ehrensberger, PhD, University at Buffalo, Buffalo, NY, USA
Characterization of Materials for Regulatory Submissions
690. Control Strategies for Improving Confidence in Dye Exclusion-Based Cell Viability Measurements, Laura Pierce1, Sumona Sarkar1, Joe Chalfoun1, Adele Peskin1, Steven Lund1, Firdavs Kurbanov1, Michael Halter1, John Elliott1, Leo Chan2, 1NIST, Gaithersburg, MD, USA, 2Nexcelom Bioscience, Lawrence, MA, USA
Dental/Craniofacial Biomaterials (SIG)
691. Nanofibrous Tissue Engineering Matrices from Poly (L-Lactide) with Improved Clinical Handling Properties for Periodontal and Craniofacial Regeneration, Seth Woodbury, W Benton Swanson, Yuji Mishina, University of Michigan, Ann Arbor, MI, USA
692. Candida albicans pathogenesis caused by cyclic mechanical deformation, Julia Kurylec, Carolina Montoya, PhD, Santiago Orrego, PhD, Temple University, Philadelphia, PA, USA
693. Tricalcium Phosphate Paste and Foam Bone Grafting Materials enhance Osteogenesis in vivo, Christine Knabe, DMD, PHD1, Dirk Barnewitz, DVM, PhD2, Antje Genzel2, Fabian Peters, phD3, Andrea Kuhr, DDS1, Benedict Stang, DDS1, Wolf-Dietrich Huebner, MD, PhD3, Michael Stiller, MD, DMD, PhD1, 1Philipps-University Marburg, Marburg, Germany, 2Veterinary Research Center, Bad Langensalza, Germany, Bad Langensalza, Germany, 3Curasan, Kleinostheim, Germany
694. Multiple Channels in I2-Tricalcium Phosphate (I2-TCP) Scaffold Promote Craniofacial Bone Tissue Regeneration, Yunqing Kang, Florida Atlantic University, Boca Raton, FL, USA
695. Craniofacial Skeletal Muscle Regeneration with Auxetic Designed Collagen-PCL Knitted Scaffolds in Alternative Cell Culture Conditions, Monica Deshpande1, Kun Luan, PhD2, Andre West, PhD1, Mahmoud Rouabhia, PhD3, Martin King, PhD1,4, 1North Carolina State University College of Textiles, Raleigh, NC, USA, 2North Carolina State University, Raleigh, NC, USA, 3Laval University, Quebec, QC, Canada, 4Donghua University, Shanghai, China
Design and Preclinical Testing of Biomaterials for Pathogen Inactivation
696. A Standardized Procedure for the Quantitative Evaluation of Residual Viral Activity on Antiviral Textiles, Ziyu Wang1, Alaowei Amanah1, Kiran Ali1, Lucy Payne1, Samantha Kisthardt2, Roger Barker1, Frank Scholle2, Jessica Gluck1, Bryan Ormond1, Kavita Mathur1, Don Tompson1, 1North Carolina State University, Raleigh, NC, USA, 2Department of Biological Sciences NCSU, Raleigh, NC, USA
697. An in vitro Operating-Room Model of Bacterial Contamination, Wenhan Zhao1, Matthew Libera1, Jordan Katz2, Lauren De Stefano2, 1Stevens Institute of Technology, Hoboken, NJ, USA, 2Orthobond Corporation, Monmouth Junction, NJ, USA
698. Mechanisms underlying bacterial interactions with breast implant textures, Sang Won Lee, PhD1,2, Erick Johnson, PhD3, J. Alex Chediak, PhD2, Hainsworth Shin, PhD2, Yi Wang, PhD2, K. Scott Phillips, PhD2, Dacheng Ren, PhD1, 1Syracuse University, Syracuse, NY, USA, 2United States Food and Drug Administration, Silver Spring, MD, USA, 3Montana State University, Bozeman, MT, USA
699. In vitro and ex vivo antibiofilm testing of a controlled release antibacterial wound protectant, Annika Hylen1, Charles Florek, PhD2, David Armbruster2, Eric Cozzone2, Dustin Williams, PhD1, 1The University of Utah, Salt Lake City, UT, USA, 2DePuy Synthes Biomaterials R&D, West Chester, PA, USA
Drug Delivery (SIG)
700. Temporally-Controlled Shape Memory Polymers for Drug Delivery, Anand Vakil, Yohely Yohely Espiritusanto, Era Jain, Mary Beth Monroe, Syracuse University, Syracuse, NY, USA
701. Sustained Release of Antiviral Agent GS-441524 from in situ Depots for COVID-19 Treatment, Divya Muthusamy, M.S.1,2, Varunaa Hemanth1, Tao Lowe, PhD1,2, 1University of Maryland College Park, College Park, MD, USA, 2University of Maryland Baltimore, Baltimore, MD, USA
702. Acemannan/alginate/biocompatible ionic liquid-based beads as a sustainable therapeutic approach, Joana Gomes1,2, Simone Silva1,2, Rui Reis1,2, Carlos Guimaraes1, 13B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimaraes, Portugal, 2ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal
703. Sustained Release of Bevacizumab Towards Improving the Treatment of Age-Related Macular Degeneration, Eman Mirdamadi1,2, Sangyoon Kim1,2, Tao Lowe1,2, 1University of Maryland, College Park, College Park, MD, USA, 2University of Maryland, Baltimore, Baltimore, MD, USA
WITHDRAWN 704. Release kinetic profiles and cytotoxicity test of a PDMS-based balloon-type implantable drug delivery device based on PDMS mixing ratios, Muhammad Tausif, MS, Sohee Kim, PhD, Aseer Intisar, Minseok S. Kim, PhD, Daegu Gyeongbuk Institute of Science & Technology(DGIST), Daegu, Republic of Korea
705. Next Generation Cancer Therapeutics: Active Targeting of Drug Encapsulated Nanogel for Her2 Positive Breast Cancer, Peidong Wu, Sankaran Thayumanavan, Uyen Huynh, Jingyi Qiu, Theeraphop Prachyathipsakul, Khushboo Singh, Jingjing Gao, University of Massachusetts Amherst, Amherst, MA, USA
706. Evaluation of Chitosan-Coated Liposome Potentials as Nano-Carriers for Laryngeal Cancer Treatment, Christian Moya-Garcia, MPhil, Nicole Li-Jessen, PhD, Maryam Tabrizian, PhD, MBA, McGill University, Montreal, QC, Canada
707. Automated Control of Photoinitiated RAFT Polymerizations in Well Plates, Jules Lee, Matthew Tamasi, Travis Meyer, Sreya Kilambi, and Adam J. Gormley, PhD, Rutgers University, Piscataway, NJ, USA
708. Slow Release of An Antileukemic Artemisinin Analog from An Injectable, Biodegradable In Situ Gelling System, John Quinlan1,2, Divya Muthusamy2, Sourabh Vellala2, Michelle Rudek, PharmD, PhD3, Curt Civin, MD1, Tao Lowe, PhD1,2, 1University of Maryland, Baltimore, Baltimore, MD, USA, 2University of Maryland, College Park, College Park, MD, USA, 3Johns Hopkins University, Baltimore, MD, USA
709. Impact of Surface Charge on Toxicity, Permeability and Cellular Interaction of Biodegradable Nanogels, Sangyoon Kim1,2, Noha Ghonim2, Tao Lowe, PhD1,2, 1University of Maryland, College Park, College Park, MD, USA, 2University of Maryland, Baltimore, Baltimore, MD, USA
710. Oxidation-sensitive polymeric micelles for cancer cell-selective drug release, Urara Hasegawa, PhD, Andre van der Vlies, PhD, Pennsylvania State University, University Park, PA, USA
711. Cyclodextrin Enhances In Situ Forming Implant Affinity with Drug and Controls Drug Release, Ningjing Zhang, Kathleen Young, Emma Henderson, Ananya Sahu, Audrey Lord, Joel Linebach, Horst von Recum, PhD, Case Western Reserve University, Cleveland, OH, USA
712. Fabrication of Chitosan-Alginate Microparticles Loaded with Simvastatin for Sustained Drug-release in vitro, Angshuman Bharadwaz, MS1, Rebekah Hutcherson2, Ambalangodage Jayasuriya, PhD1,2, 1The University of Toledo Main Campus, Toledo, OH, USA, 2The University of Toledo Health science Campus, Toledo, OH, USA
713. Inhalable SARS-CoV-2 Mimetic Particles Induce Pleiotropic Antigen Presentation, Atip Lawanprasert, Andrew Simonson, PhD, Sarah Sumner, McKayla Nicol, Sopida Pimcharoen, Girish Kirimanjeswara, PhD, Scott Medina, PhD, the Pennsylvania State University, University Park, PA, USA
714. Permeation Properties of Polyurethanes for Continuous Glucose Monitors, Andre Martinez, PhD, Nicole Gardner, Jia Chen, Ajay Padsalgikar, PhD, DSM Biomedical, Exton, PA, USA
715. Folic acid conjugated and zoledronic acid loaded microparticles for targeted drug delivery to activated macrophages and treatment of osteoarthritis, Yohely Espiritusanto, BS1,2, Kaixiang Zhang, BS1,2, Amelia Gilbert3, Era Jain, PhD1,2, 1Syracuse University, Syracuse, NY, USA, 2Syracuse University Bioinspired, Syracuse, NY, USA, 3Rochester Institute of Technology, Rochester, NY, USA
716. Paclitaxel Loaded Polycaprolactone Particles for Treating Endometrial Cancer, Claire Rowlands, Megan Dwyer, Anastasiia Aronova, Brittany Givens, PhD, University of Kentucky, Lexington, KY, USA
717. Improving Non-viral Gene Delivery in Jurkats via Cell Penetrating Peptides, Brian Austin-Carter, Anna Unser, Jacob Elmer, PhD, Noelle Comolli, PhD, Villanova University, Villanova, PA, USA
718. Multilayer Polymer Films for Interval Delivery of 5HT2A Agonists, Thomas Werfel, Mehjabeen Hossain, Suresh Sulochana, Chalet Tan, John Rimoldi, Glenn Walker, University of Mississippi, University, MS, USA
719. Temozolomide Delivery via Peptide Micelles in Glioblastoma Treatment, Abigail Sottile1, Megan Pitz, Angela Alexander-Bryant, 1Clemson University, Stamford, CT, USA
720. PLA-PCL Microsphere Formulation to Deter Prescription Opioid Abuse via Smoking, Anastasiia Vasiukhina, Sheryhan Gad, Elyssia Wellington, Danielle Wilmes, Yoon Yeo, Luis Solorio, Purdue University, West Lafayette, IN, USA
722. Preparation and evaluation of doxorubicin containing an intratumorally injectable, click-cross-linked hyaluronic acid hydrogel, Hyeon Jin Ju, Moon Suk Kim, Ajou University, Suwon, Republic of Korea
723. Hydrogel delivery device for the in-vitro sustained release of active rhGALNS enzyme, Silviya Zustiak1, Michael Flanagan2, Saahil Sheth1, Qi Gan2, Samuel Ruesing1, Adriana Montano2, 1Saint Louis University, St Louis, MO, USA, 2Saint Louis University, School of Medicine, Saint Louis, MO, USA
724. Doxycycline loaded thiol-ene microparticles made via suspension polymerization, Chipo Chapusha, Amol Janorkar, University of Mississippi Medical Center, Jackson, MS, USA
725. Gellan gum and trilysine hydrogels with tunable mechanical properties for drug delivery, Carolina Villarreal-Otalvaro1,2, Jeannine Coburn2, 1Boston Scientific, Marlborough, MA, USA, 2Worcester Polytechnic Institute, Worcester, MA, USA
726. Investigation of Macromolecular Transport Through Tunable Collagen Hyaluronic Acid Matrix, Mazin Hakim, Brian Jun, Adib Ahmedzadegan, Paulina Babiak, Qinghua Xu, Kevin Buno, Julie Liu, Arezoo Ardekani, Pavlos Vlachos, Luis Solorio, Purdue University, West Lafayette, IN, USA
727. Characterizing the Interactions Between Gene Delivery Polyplexes and Bio-Inspired Polymeric Surface Coatings for Localized Gene Therapy, Sydney Hall, Sailesti Joshi, Christina Holmes, PhD, Florida State University, Tallahassee, FL, USA
Drug Delivery for Cardiovascular Applications
728. Design of a targeted nanomedicine to diminish oxidative stress in atherosclerosis, Ozgul Gok, PhD1, Rabia Guner2, Irem Soyhan2, 1Department of Medical Engineering, Faculty of Engineering, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 2Biomedical Engineering Program, Graduate School of Natural and Applied Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
729. Epsin-Mimetic Peptide Delivery Strategies from Electrospun Meshes for Endothelialization of Vascular Grafts, Mahyar Sameti, PhD1, Shirin Changizi1, Hong Chen, PhD2, Chris Bashur1, 1Florida institute of technology, Melbourne, FL, USA, 2Harvard Medical School, Boston, MA, USA
Engineered Biomaterials for Neural Applications
731. Synthetic Ligand-Receptor Binding for Targeted Delivery to the Injured Spinal Cord, Andrew Ciciriello, Bapurao Surnar, Shanta Dhar, Courtney Dumont, University of Miami, Coral Gables, FL, USA
733. Machine-Assisted Discovery of Chondroitinase ABC Complexes Towards Sustained Neural Regeneration, Eugene Cheong1, Shashank Kosuri1, Carlos Borca2, Heloise Mugnier1, Matthew Tamasi1, Isabel Perez1, Rene Schloss1, Li Cai1, Michael Webb2, Adam Gormley1, 1Rutgers University, Piscataway, NJ, USA, 2Princeton University, Princeton, NJ, USA
734. Sustained Growth Factor Delivery from Hyaluronic Acid Hydrogels for Spinal Cord Regeneration, Pablo Ramos Ferrer, Shelly Sakiyama-Elbert, The University of Texas at Austin, Austin, TX, USA
735. Direct Laser Assembly of Organic Bioelectronics, Omid Dadras-Toussi, Mohammad Reza Abidian, PhD, University of Houston, Houston, TX, USA
736. Creating 3D Aligned Collagen I Scaffolds for Peripheral Nerve Repair, Mackenzie Lewis, Gabriel David, Danielle Cagna, Alan Woessner, Kyle Quinn, PhD, Luis Pinzon-Herrera, Jorge Almodovar, PhD, Young Hye Song, PhD, University of Arkansas, Fayetteville, AR, USA
737. Biopreservation of Living Tissue Engineered Neural Networks Under Hypothermic Conditions for Efficient Storage and Transport, Dimple Chouhan, PhD, Wisberty Gordian Velez, Kevin Browne, Bella Chau, Robert Shultz, Kacy Cullen, PhD, University of Pennsylvania, Philadelpohia, PA, USA
738. Modeling human brain angiogenesis with a tissue-engineered brain microvessel, Nan Zhao, Peter Searson, Johns Hopkins University, Baltimore, MD, USA
739. The Effects of Hyaluronic Acid Molecular Weight on the Differentiation Potential of Human Neural Stem Cells in 3D Contexts, Anna Gonzalez, Meagan McKee, Carson Koch, Andrea Jimenez-Vergara, Dany Munoz-Pinto, Trinity University, San Antonio, TX, USA
740. Controlling hiPSC-derived Neural Stem Cells Behavior Using Electrical Stimulation, Sabrina Coffman, Metin Uz, Cleveland State University, Cleveland, OH, USA
741. Aligned Nanofiber/Hydrogel Composite Scaffolds for Peripheral Nerve Regeneration, Nikolas Belanger1, Brandon Herb1, Cameron Burns1, Jacob Carter1, Shrey Dalwaldi1, Grace Gilbert2, David Fuller2, Sebastian Vega1, Vince Beachley1, 1Rowan University, Glassboro, NJ, USA, 2Cooper Medical School of Rowan University, Camden, NJ, USA
742. Utilizing Spatially Patternable Hydrogel Nanofibers to Recapitulate the Neural Stem Cell Niche In Vitro, Gregory Grewal, Christopher Highley, PhD, University of Virginia, Charlottesville, VA, USA
743. Driving Oligodendrocyte Progenitor Cell Differentiation in 3D Hydrogels via Biomaterial Stiffness and Topographical Cues, Rachel Mazur, Hannah Hockensmith, Kyle Lampe, University of Virginia, Charlottesville, VA, USA
744. Brain Cancer Cell-Derived Matrix Alters Neural Astrocyte Migration and Metabolic Activity, Rebecca Louisthelmy, Brycen Burke, Chase Cornelison, PhD, University of Massachusetts Amherst, Amherst, MA, USA
745. Creation of a 3D-bioprinted neuronal spinal cord scaffold, Daeha Joung, Virginia Commonwealth University, Richmond, VA, USA
Engineering Cells and Their Microenvironments (SIG)
746. Extracellular Matrix Hydrogel Composition Drives 4T1 Spheroid Invasion, Elizabeth Brooks, Matthew Wolf, Michael Buckenmeyer, National Cancer Institute, Frederick, MD, USA
747. Identifying the Impact of Osteoarthritis Synoviocytes and Cellular Senescence on Stem Cell Differentiation Potential and Altered Cellular Functions of Neighboring MSCs in 3D Human Joint Tissue Platform, Ji Young Choi, PhD1, John Fisher, PhD, Bhushan Mahadik, PhD, 1University of Maryland, College Park, MD, USA
748. Engineering of cell surface with synthetic DNA using lipid insertion or click conjugation, Xuelin Wang, Connie Wen, Brandon Davis, Peng Shi, Lidya Abune, Kyungsene Lee, Cheng Dong, Yong Wang, The Pennsylvania State University, University Park, PA, State College, PA, USA
749. Hydrogel cultures reveal TRPV4 regulation of myofibroblast activation and proliferation in Valvular Interstitial Cells, Dilara Batan1, Douglas Peters, PhD1, Brian Aguado, PhD1, Megan Schroeder, PhD1, Robert Weiss, MD2, Kristi Anseth, PhD1, 1University of Colorado, Boulder, Boulder, CO, USA, 2University of Iowa, Iowa City, IA, USA
750. Developing electrospun meshes to model the lymph node stromal cell network, Tochukwu Ozulumba, PhD, Greg Grewal, Christopher Highley, PhD, Rebecca Pompano, PhD, University of Virginia, Charlottesville, VA, USA
751. Regulatory T Cell Activation in Simulated Microgravity Using a Multi-axis 3D printed Rotary Cell Culture System, Emily Adler, Niroshan Anandasivam, Kylie Gallagher, Claire Hilburger, Matthew Rosenwasser, Derfogail Delcassian, University of California, Berkeley, Berkeley, CA, USA
752. Development of a streptavidin-biotin hydrogel scaffold for modulating T cell activation, Niroshan Anandasivam, Derfogail Delcassian, University of California, Berkeley, Berkeley, CA, USA
753. Influence of Tethered Cadherin on Human Induced Pluripotent Neural Stem Cells, McKay Cavanaugh, Rebecca Willits, PhD, Northeastern University, Boston, MA, USA
754. Influence of adipose tissue harvest condition on the in vitro adipogenic differentiation of human stem cells in three-dimensional spheroid culture, Pallabi Pal, PhD, Abelardo Medina, MD, PhD, Courtney Cates, MS, Ratna Bollavarapu, Jon Person, Osvaldo Rivera Gonzales, PhD, Benjamin McIntyre, MD, Joshua Speed, PhD, Amol Janorkar, PhD, University of Mississippi Medical Center, Jackson, MS, USA
755. Using Peptide Stereochemistry to Control Physical Features of Self-assembling Hydrogels, Jonathan Florian, Israt Jahan Duti, Anna Kittel, Connor Amelung, Rachel Letteri, PhD, Kyle Lampe, PhD, University of Virginia, Charlottesville, VA, USA
756. Conformal Encapsulation of Stem Cells Using Modified Hyaluronic Acid, Jack Whitewolf, Chris Highley, PhD, University of Virginia, Charlottesville, VA, USA
757. Glycosaminoglycan sulfation differentially regulates FGF-2 mediated human neural stem cell (hNSC) proliferation and cell cycle progression, Nathan Gonsalves, Braxton Goodnight, Lohitash Karumbaiah, PhD, University of Georgia, Athens, GA, USA
Engineering the Lung Microenvironment
758. Micro-Environmental Attributes Regulate Lung Fibroblast Phenotypes, Caymen Novak, PhD, Samir Ghadiali, PhD, Megan Ballinger, PhD, The Ohio State University, columbus, OH, USA
759. Establishment of a mechanically and biochemically tunable culture platform to probe key factors in macrophage responses during the initiation and progression of fibrosis, Kartik Bomb, April Kloxin, PhD, Catherine Fromen, PhD, University of Delaware, Newark, DE, USA
760. Coating Morphology and Corticosteroid Delivery Impact Upper Airway Microbiome in Intubated Injured Swine, Solaleh Miar, PhD1,2, Gabriela Gonzales, MSc1, Ronit Malka, MD3, Gregory Dion3,4, Teja Guda, PhD1, Stacy Cook, MD3, 1The University of Texas at San Antonio, SAN ANTONIO, TX, USA, 2Oak Ridge Institute for Science and Education, Belcamp, MD, USA, 3Brooke Army Medical Center, Fort Sam Houston, TX, USA, 4US Army Institute of Surgical Research, Fort Sam Houston, TX, USA
761. Variations in Mechanical Stiffness Alter Microvascular Sprouting and Stability in a PEG Hydrogel Model of Idiopathic Pulmonary Fibrosis, Julie Leonard-Duke, Shayn Peirce, PhD, Lakeshia Taite, PhD, University of Virginia, Charlottesville, VA, USA
Functionality of Engineered Cardiovascular Tissues
762. Mechanical Characterization and Preclinical Evaluation of a Bioengineered Human Acellular Vessel for Vascular Patch Applications, Matthew Niesslein, MS1, Craig Cronin, BSE1, Heather Prichard, PhD1, Jeffrey Lawson, MD, PhD1,2, Laura Niklason, MD, PhD1, Robert Kirkton, PhD1, 1Humacyte, Inc., Durham, NC, USA, 2Duke University, Durham, NC, USA
Generation After Next Biomaterial-Based Vaccines
763. Surface Conjugation to Ace-DEX Microparticles Augments Matrix-2 Ectodomain-Based Influenza Vaccine Efficacy, Cole Batty1, Kathryn Moore, PhD1,2, Eva Amouzougan, PhD1, Eric Bachelder, PhD1, Kristy Ainslie, PhD1,2, 1University of North Carolina - Chapel Hill, Chapel Hill, NC, USA, 2North Carolina State University, Raleigh, NC, USA
Immune Cell Interfaces: Immunotherapies, Implants, and Immunobiology
430. Inflammatory and Immunological Response to Orthopedic Implants, Derek Avery, Lais Morandini, PhD, Rene Olivares-Navarrete, PhD; Virginia Commonwealth University, Richmond, VA, USA
764. Using Light Sheet Fluorescence Microscopy to Contextualize the Immune Responses to Biomaterials in Trauma Microenvironment, Tran Ngo, Sabrina Destefano, Yijun Su, Harshad Vishwasrao, PhD, Jiamin Liu, PhD, Hari Shroff, PhD, Kaitlyn Sadtler, PhD, National Institutes of Health, Bethesda, MD, USA
765. IL-6/ATP Dependent Microglial Disfunction is Potentially Diminished by Treatment with Cannabidiol, Daniel Yeisley, Mariah Hahn, PhD, Rensselaer Polytechnic Institute, Troy, NY, USA
766. Paired Single Cell Gene Expression and T cell Receptor Sequencing of Fibrotic Capsules Surrounding Breast Implants, Kavita Krishnan1, Joscelyn Mejias, PhD1, Locke Davenport Huyer, PhD1,2, Gedge Rosson, MD1, Jennifer Elisseeff, PhD1, 1Johns Hopkins University, Baltimore, MD, USA, 2Dalhousie University, Halifax, NS, Canada
Immune Engineering (SIG)
767. Natural Killer based cellular therapy as a treatment for melanoma, Abhirami Suresh, Sahil Inamdar, Abhinav Acharya, Arizona State University, Tempe, AZ, USA
768. Gelatin Methacrylate Hydrogels as Engineered Niches for In-Situ Granulopoiesis and Delivery of Hematopoietic Stem and Progenitor Cells, Tomas Gonzalez-Fernandez, Alejandro Vargas, Tyler Powel, Kent Leach, Simon Scott, University of California Davis, Davis, CA, USA
769. Utilizing Microporous Annealed Particle Scaffold as a Platform for IL-33-Mediated Immunomodulation, Colleen Roosa, Samantha Lempke, Sarah Ewald, PhD, Donald Griffin, PhD, University of Virginia, Charlottesville, VA, USA
Immunomodulatory Biomaterials
770. Intratumoral Delivery of Immunomodulatory mRNA Polymeric Nanoparticles for Breast Cancer, Sarah Neshat, Joshua Doloff, PhD, Jordan Green, PhD, Stephany Tzeng, PhD, Johns Hopkins University School of Medicine, Baltimore, MD, USA
771. Rational Vaccinology to Protect Against Cancer and Infectious Disease Using Spherical Nucleic Acids, Michelle Teplensky, PhD, Chad Mirkin, PhD, Northwestern University, Evanston, IL, USA
772. Antigen-specific modulation of immune responses using ovalbumin-poly(lactic-co-glycolic acid) nanoparticles, Brianna Scotland1, Andrea Cottingham1, Ryan Pearson, PhD1,2, 1University of Maryland School of Pharmacy, Baltimore, MD, USA, 2University of Maryland School of Medicine, Baltimore, MD, USA
773. Poly(lactic acid) Nanoparticle Modulation of Macrophage Inflammatory Responses, Andrea Cottingham1, Jackline Lasola2, Brianna Scotland1, Nhu Truong1, Charles Hong, MD, PhD2, Paul Shapiro, PhD1,3, Ryan Pearson, PhD1,3, 1University of Maryland School of Pharmacy, Baltimore, MD, USA, 2University of Maryland School of Medicine, Baltimore, MD, USA, 3Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA
774. Computational Design of CCL2 Sequestering Anti-Inflammatory Hydrogels, Abdul-Rahman Azizogli1, Erika Davidoff2, Joseph Dodd-o1, Ka Kyung Kim1, Zain Siddiqui1, Amanda Acevedo-Jake1, Jay Sy, PhD2, Vivek Kumar, PhD1, 1New Jersey Institute of Technology, Newark, NJ, USA, 2Rutgers University, Piscataway, NJ, USA
775. Engineering an immunomodulatory hydrogel using tolerogenic trophoblast exosomes, Shivani Hiremath, M.S, Jessica Weaver, Arizona State University, Tempe, AZ, USA
776. Understanding the Effect of TLR activation on mRNA Delivery, Claire Hilburger, Derfogail Delcassian, PhD, UC Berkeley, Berkeley, CA, USA
777. Synergistic Immunomodulatory Effects of Transferred M2 Macrophages and IL4-releasing Microparticles in Murine Hindlimb Ischemia, Gregory Risser, Kara Spiller, Drexel University, Philadelphia, PA, USA
778. Nucleic Acid Delivery from a Bioactive Silk Platform for Tissue Repair, Muhammad Raisul Abedin, Kaushal Rege, Arizona State University, Tempe, AZ, USA
779. Immunomodulatory Enzyme Immobilized in Co-assembling Peptide Hydrogels, Bethsymarie Soto-Morales, PhD, Renjie Liu, PhD, Gregory Hudalla, PhD, University of Florida, Gainesville, FL, USA
780. Biomaterials-based Immunomodulation and Co-Stimulatory Blockade for Allograft Survival Enhancement in Murine Vascularized Composite Allotransplantation, Sven Sommerfeld, PhD1, Xianyu Zhou, MD, PhD2, Joscelyn Mejias, PhD1, Byoung Chol Oh, DVM, PhD1, David Maestas, II1, Georg Furtmuller, MD1, Jennifer Elisseeff, PhD1, Gerald Brandacher, MD1, 1Johns Hopkins University School of Medicine, Baltimore, MD, USA, 2Shanghai Jiaotong University School of Medicine, Shanghai, China
781. In vitro Response of Human Buccal Epithelial Cells to a Bladder Patch for Vesicovaginal Fistula Repair, Ilaha Isali, MD, Phillip McClellan, PhD, Thomas Wong, Shubham Gupta, MD, Rachel Pope, MD, James Anderson, MD, PhD, Adonis Hijaz, MD, Ozan Akkus, PhD, Case Western Reserve University, Cleveland, OH, USA
782. Analyzing Immune Response to Engineered Hydrogels by Hierarchical Clustering of Inflammatory Cell Subsets, Marc Fernandez-Yague, PhD, Lauren Hymel, Edward Botchwey, PhD, Andres J. Garcia, PhD, Georgia Institute of Technology, Atlanta, GA, USA
783. Dexamethasone Eluting Polycaprolacton-Poly(lactic-co-glycolic) acid Stent for Treatment of Tracheal Restenosis, Jacob Morand1, Phillip McClellan, PhD1, Isali Isali, MD1, Mark Weidenbecher, MD2, Ozan Akkus, PhD1, 1Case Western Reserve University, Cleveland, OH, USA, 2Louis Stokes Cleveland Veteran Affairs Medical Center, Cleveland, OH, USA
Innovation and Entrepreneurship in Biomaterials Education
784. Can Sound Reducing Foams Decrease Noise in a Neonatal Intensive Care Unit (NICU) Incubator?, Sally Shady1, Hailey Thomas, Sean Pelcher, Douglas Chacon, Jabril Elghamrawi, Marwa Khalil2, 1Stevens Institute of Technology, Hoboken, NJ, USA, 2Hackensack Meridian Hospital, Hackensack, NJ, USA
In-Vitro Assessment of Long-Term Implants and Explant Analysis
787. Wireless and Battery-less Surveillance System of Blood Flow in Textile-based Vascular Grafts, Xiaoqi Tang, PhD1, Martin King, PhD1,2, 1North Carolina State University, Raleigh, NC, USA, 2Donghua University, Shanghai, China
Leveraging Advanced Biomaterials for Infectious Diseases
788. Improving antibody and T-cell responses to subunit influenza vaccines using supramolecular assembly and randomized T-helper epitopes, Emily Roe, Nicole Votaw, PhD, Hector Miranda, Nicholas Heaton, PhD, Joel Collier, PhD, Duke University, Durham, NC, USA
789. Advanced Biomaterials and Oxygen Join Forces to Reinforce COVID-19 Vaccines, Thibault Colombani, Ph.D.1, Sidi Bencherif, Ph.D.1,2,3, 1Northeastern University, boston, MA, USA, 2Harvard University, Boston, MA, USA, 3UTC CNRS UMR 7338, Compiegne, France
Machine Learning in Biomaterials Chemistry
790. In Silico Optimization of Microporous Annealed Particle Hydrogel for Endothelial Cell Migration, Lauren Pruett, BS, Alex Taing, Neharika Singh, Donald Griffin, PhD, University of Virginia, Charlottesville, VA, USA
Nanomaterials (SIG)
791. Development of a Novel Tandem Peptide for Delivery of siRNA for Treatment of Glioblastoma Multiforme, Jessica Boulos, Jorrian Abadeer, Tyler Willis, Angela Alexander-Bryant, Clemson University, Clemson, SC, USA
792. Carbonized Lignin Nanofibers for Sustainable Biomedical Applications, Abigail Heinz, Dave Jao, Vincent Beachley, Rowan University, Glassboro, NJ, USA
793. Synthesis and Characterization of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles-Encapsulated Liposomes as a Novel pH-Responsive T1-Weighted MRI Contrast Agent for Cancer Diagnosis, Shiva Rahmati, Allan David, PhD, Auburn University, Auburn, AL, USA
794. Porous Laponite Nanoclay-Hydroxyapatite Composite Scaffolds: Characterization and Understanding Cell-Material Interactions, Solaleh Miar, PhD1,2, Mistica Lozano Perez2, Akhilesh K. Gaharwar, PhD3, Teja Guda, PhD2, 1Oak Ridge Institute of Science and Education, Oak Ridge, TN, USA, 2The University of Texas at San Antonio, San Antonio, TX, USA, 3Texas A&M University, College Station, TX, USA
795. BioPapers: An Innovative Approach to 3D Cell Scaffolds, James Dolgin1, Stephen Farias, PhD1, Zahra Ghassemi, PhD2, Gymama Slaughter, PhD2, 1Materic Group, Baltimore, MD, USA, 2University of Maryland, Baltimore County, Baltimore, MD, USA
796. Quantification of Mucoadhesive Micelles Retention in Nasal Applications, Frances Lasowski, Talena Rambarran, Lina Liu, Ben Muirhead, Heather Sheardown, McMaster University, Hamilton, ON, Canada
Naturally Derived Biomaterials for Cardiovascular Engineering
797. Development of a Novel Surgical Glue Using Fibrin-Based Nanoparticles, Nina Moiseiwitsch, BS1,2, Nicole Zwennes1, Grant Scull, BS1,2, Ashley Brown, PhD1,2, 1North Carolina State University, Raleigh, NC, USA, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
798. Ascending and Descending ECM Hydrogels for Modeling Aortic Aneurysms, Yoojin Lee, PhD1,2, David Kaczorowski, MD2,3, Julie Phillippi, PhD1,2, 1University of Pittsburgh, Pittsburgh, PA, USA, 2McGowan Institute of Regenerative Medicine, Pittsburgh, PA, USA, 3University of Pittsburgh Medical Center, Pittsburgh, PA, USA
NSF-Funded Biomaterials Education Projects
799. Enhancing Bioengineering Undergraduate Studentsa** Learning and Research Experiences through Hands on Experiments on Bio-Nanoengineering, Narayan Bhattarai, North Carolina Agricultural and Technical State University, Greensboro, NC, USA
Ophthalmic Biomaterials (SIG)
800. Cerium oxide nanoparticles to mitigate oxidative stress in ophthalmic applications, Mir Patel1, John Burn2, 1University of Georgia, athens, GA, USA, 2Unvirsity of Georgia, athens, GA, USA
801. Evaluation of Corneal Endothelium Barrier Function on Electrospun Scaffolds, Garyn Levitan, Meiji Wang, Nasif Mahmood, Jessica Gluck, PhD, Michael Daniele, PhD, North Carolina State University, , Raleigh, NC, USA
802. A Decellularized Dehydrated Human Amniotic Membrane-Derived Biomaterial Supports Human Corneal Epithelial Cell Function and Inflammatory Response, Anna Gosiewska, PhD1, Yong Mao, PhD2, Nicole Protzman, BS, MS3, Nikita John, BS2, Adam Kuehn, MD1, Desiree Long, MBA1, Raja Sivalenka, PhD1, Luis Martinez, BS, MBA1, Radoslaw Junka, PhD1, Robert Hariri, MD, PhD1, Stephen Brigido, DPM1, 1Celularity Inc., Florham Park, NJ, USA, 2Rutgers University, Piscataway, NJ, USA, 3Healthcare Analytics, LLC, Easton, PA, USA
803. Contact Lens Mediated Drug Delivery for the Treatment of Ocular Diseases, Talena Rambarran, PhD1, Lina Liu1, Heather Sheardown, PhD1, Darren Stirland, PhD, Michael Manzo, PhD, Brenda Mann, PhD2, 1McMaster University, Hamilton, ON, Canada, 2Kiora Pharmaceuticals, Salt Lake City, UT, USA
Orthopaedic Biomaterials (SIG)
804. Polyphosphate dicalcium phosphate dehydrate (P-DCPD): A better strontium-eluting bone substitute (BS) for the bone defect repair, David Markel, MD.1,2, Therese Bou-Akl, MD., PhD.1,2, Tong Shi1, Weiping Ren, MD., PhD.2,3, 1Wayne State University, Detroit, MI, USA, 2Ascension Providence Hospital, Southfield, MI, USA, 3Virotech Co., Inc., Troy, MI, USA
805. Two Distinct Local Structures with Different Mechanical Characteristics in Osteogenesis Imperfecta-related Gly Substitutions Type I Collagen, Haoyuan Shi, Liming Zhao, Chenxi Zhai, Jingjie Yeo, Cornell University, Ithaca, NY, USA
806. Evaluation of Titanium Implant Osseointegration in a Translational Clinical Type 2 Diabetic Rat Model, Jingyao Deng1, David Cohen, MD1, Zvi Schwartz, DMD, PhD1,2, Barbara Boyan, PhD1,3, 1Virginia Commonwealth University, richmond, VA, USA, 2University of Texas Health Science Center at San Antonio, San Antonio, TX, USA, 3Georgia Institute of Technology, Atlanta, GA, USA
807. Solution deposited hydroxyapatite on 3D printed titanium reveals contact osteogenesis in a sheep gap-defect model, Rajendra Kasinath, PhD, PE, Stephanie Vass, Danny Ettensohn, Bryan Smith, PhD, DePuy Synthes, Warsaw, IN, USA
808. Release Kinetics and Efficacy of a Broad-spectrum Antimicrobial Peptide from Poly(Methyl Methacrylate) Bone Cement, Grahmm Funk, B.S., B.S.1, Kara Hageman, B.S., MPH1, Amanda Varner, B.S.1, Kyle Boone, PhD2, Nilan Kamathewatta, PhD2, Candan Tamerler, PhD2, Terence McIff, PhD, MBA1, 1University of Kansas Medical Center, Kansas City, KS, USA, 2University of Kansas, Lawrence, KS, USA
809. Characterizing the Internal Porous Structure of the Equine Proximal Sesamoid Bone Using Fast Fourier Transforms, Joseph Davis1, Hope Sage2, Jennifer Janes, DVM, Ph.D., Dipl. ACVP1, James MacLeod, VMD, Ph.D.1, Guigen Zhang, Ph.D.1, 1University of Kentucky, Lexington, KY, USA, 2Texas Christian University, Fort Worth, TX, USA
810. A Braided Polylactic Acid Scaffold for Rotator Cuff Tissue Engineering, Yihan Huang1, Jacqueline Cole, PhD2, Martin King, PhD1,3, Jessica Gluck1, Edwin Cadet4, 1North Carolina State University, Raleigh, NC, USA, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 3Donghua University, Shanghai, China, 4Raleigh Orthopaedic Clinic, Raleigh, NC, USA
811. Characterization of Antioxidant MnPBuOE Encapsulated in Chondroitin Sulfate-A Microparticles for Long-term ROS Scavenging, Kayla Ney, Fei San Lee, Rebecca Wachs, PhD, University of Nebraska Lincoln, Lincoln, NE, USA
812. What Effect Does a Self-Tensioning Suture Have on Tendon Tissue?, David Spenciner, ScM, MBA1,2, Dayna Hutchens, BS2, Ryan Stuart, MS2, Dennis Connelly, MS2, Joseph Algeri, BS2, Vivian Liang, MEng2, Sue Kurth, MBA2, Brigitte von Rechenberg, Dipl. ECVS3, Salim Darwiche, PhD3, 1Rensselaer Polytechnic Insitute, Troy, NY, USA, 2DePuy Synthes Mitek Sports Medicine, Raynham, MA, USA, 3University of Zurich, Zuerich, Switzerland
813. Application of Electron Microscopy in Advanced Musculoskeletal Infection Research, Bingyun Li, PhD, West Virginia University, Morgantown, WV, USA
814. Mechanical Strength and Bioactivity Assessment of PEGDMA-based Injectable and Photocurable Bone Tissue Scaffolds, Sarit Dhar1, Angshuman Bharadwaz, MS2, Ambalangodage Jayasuriya, PhD1,2, 1The University of Toledo Health Science Campus, Toledo, OH, USA, 2The University of Toledo Main Campus, Toledo, OH, USA
815. Particle Size and pH Effects of Borate Bioactive Glass and Poly(Methyl Methacrylate) Bone Cement Composite on Bacterial Growth, Kara Hageman, MPH1,2, Grahmm Funk, BS, BS2, Rebekah Blatt3, Richard Brow, PhD3, Terence McIff, PhD, MBA2, 1The University of Kansas, Lawrence, KS, USA, 2The University of Kansas Medical Center, Kansas City, KS, USA, 3Missouri University of Science and Technology, Rolla, MO, USA
816. Polyhydroxyalkanoate Coating on Silver Loaded Titania Nanotubes: Osteogenic and Antibacterial Applications, Syeda Ammara Batool1, Muhammad Atiq Rehman1, Ipsita Roy2, Aldo Boccaccini3, 1Institute of space Technology, Islamabad, Pakistan, 2University of Sheffield, Sheffield, United Kingdom, 3University of Erlangen-Nuremberg, Erlangen, Germany
817. Effect of electrode design on the melt electrowriting of sinusoidal structures, Biranche Tandon, PhD1,2, Andreas Zuge1, Simon Luposchainsky1,2, Paul Dalton, PhD1,2, 1University of Wurzburg, Wurzburg, Germany, 2Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, OR, USA
818. Effects of Carbide and Sliding Amplitude on Single Asperity Nanowear of CoCrMo Alloys, Yangping Liu, Hwaran Lee, Annsley Mace, Jeremy Gilbert, Clemson University - Medical University of South Carolina Bioengineering Program, Charleston, SC, USA
Probing Nanomaterial Interactions at Molecular and Cellular Levels
819. Investigating Stereochemically-Driven Peptide Assembly via Molecular Dynamics Simulations, Clare Cocker, Liza Harold, Kyle Lampe, PhD, Rachel Letteri, MS, PhD, University of Virginia, Charlottesville, VA, USA
820. An Electrochemical Sensor for Glucose and Oxygen Detection, Lauren Bell, Yu Zhao, PhD, Frederique Yiannikouris, PhD, Guigen Zhang, PhD, David Alexander, University of Kentucky, Lexington, KY, USA
821. Nanoparticles Increase Calcium Internalization via TRPV4: Towards Improved Understanding of Nanoparticle Delivery Technologies, Jaspreet Singh Nagi, MS, Amber Doiron, PhD, University of Vermont, Burlington, VT, USA
822. Development of Single-Walled Carbon Nanotube-based Biosensors for the Detection of Ions in Ocular Surface, Nasif Mahmood, Hannah Dewey, Januka Budhathoki-Uprety, PhD, Jessica Gluck, PhD, North Carolina State University, Raleigh, NC, USA
823. Characterization of Nanobubble Ultrasound Contrast Agents in Human Whole Blood, Michaela Cooley1, Eric Abenojar, PhD1, Anirban Sen Gupta, PhD1, Michael Kolios, PhD2, Agata Exner, PhD1, 1Case Western Reserve University, Cleveland, OH, USA, 2Ryerson University, Toronto, ON, Canada
Real-Time Monitoring of Stem Cell Fates and Differentiation
824. Nanofibrillar scaffold for monitoring induced pluripotent stem cell fate in 3D culture system, Wanho Cho, Wei Mao, Jaekeun Park, Oanh-Vu Pham-Nguyen, Miso Lee, Hoai-Thuong Bui, Hyuksang Yoo, Kangwon National University, Chuncheon-si, Republic of Korea
Smart Biomaterials for Drug Delivery
825. Cationic Nanogels for Oral Targeted siRNA Delivery to Macrophages for Treatment of Inflammatory Bowel Diseases, Olivia Lanier, PhD, Abielle D'Andrea, Aaliyah Shodeinde, Nicholas Peppas, ScD, University of Texas at Austin, Austin, TX, USA
826. Bacteria-Triggered Antimicrobial Release from Complexation-Loaded Polyelectrolyte Microgels, Xixi Xiao, Matthew Libera, Stevens Institute of Technology, Hoboken, NJ, USA
827. Redox-Responsive Hydrogels with Decoupled Initial Stiffness and Degradation, Carly Battistoni, Charng-yu Lin, PhD, Julie Liu, PhD, Purdue University, West Lafayette, IN, USA
828. Surfactant Interactions and Solvent Solubility Modulate Small Molecule Release from Emulsion Electrospun Fibers, Justin Lehtinen, Pamela Johnson, PhD, Jennifer Robinson, PhD, University of Kansas, Lawrence, KS, USA
829. Scalable and Continuous Fabrication of Multifunctional Nanogels for Drug Delivery, Da Huang, PhD, Hu Yang, PhD, Missouri University of Science and Technology, Rolla, MO, USA
State-of-the-Art in Sterilization of Biomaterials: Existing Modalities and Novel Techniques Under Development
830. Manufacturing of sterile drug-loaded scaffolds in a single-step process, Victor Santos-Rosales, PhD, Beatriz Magarinos, PhD, Carmen Alvarez-Lorenzo, PhD, Carlos Garcia-Gonzalez, PhD, Universidade De Santiago de Compostela, Santiago de Compostela, Spain
Stimuli-Responsive Materials for Tissue Engineering and Regenerative Medicine
833. Shape Memory Polymer Hydrogels with Cell-Responsive Degradation for Crohna**s Fistula Healing, Henry Beaman, Jr.1, Priya Ganesh1, Bryanna Howes2, Mary Beth Monroe, PhD1, 1Syracuse University, Syracuse, NY, USA, 2Le Moyne College, Syracuse, NY, USA
835. Molecular Mechanisms of a Thermo- and Ion-responsive Silk-elastin-like Protein, Haoyuan Shi1, Ting Ji2, Chenxi Zhai1, Junting Lu2, Wenwen Huang2,3, Jingjie Yeo1, 1Cornell University, Ithaca, NY, USA, 2The Zhejiang University-University of Edinburgh Institute, Haining, Zhejiang, China, 3Zhejiang University, Xihu, Hangzhou, Zhejiang, China
836. Bioprinting Ultrasound-Responsive Particles for Remote-Controlled Cellular Manipulation in Tissue Constructs, Mary Lowrey, B.S., Anthony Tahayeri, Katherine Huynh, Luiz Bertassoni, PhD, Carolyn Schutt, PhD, Oregon Health and Science University, Portland, OR, USA
837. Tuning Hydrogel Mechanics with Dynamic Covalent Chemistry, Vivian Zhang1, Boyeong Kang1, Joseph Accardo1, Ik Sung Cho2, Jae-Won Shin2, Julia Kalow1, 1Northwestern University, Evanston, IL, USA, 2University of Illinois at Chicago, Chicago, IL, USA
838. A novel injectable smart piezoelectric hydrogel for periodontal disease treatment with both antibacterial and tissue regeneration effects, Lina Lopera, DDS1, Carolina Montoya, PhD1, Santiago Correa, PhD, Santiago Orrego, PhD1, 1Temple University, Philadelphia, PA, USA
839. 3D-Printed Conductive Polymeric Scaffolds with DC Electrical Stimulation for Enhanced Bone Regeneration, Damion Dixon, Cheryl Gomillion, PhD, University of Georgia, Athens, GA, USA
840. Creating Force-Responsive Polymeric Materials by Incorporating Synthetic Cryptic Crosslinking Sites, Adrian Lorenzana, Shelly Peyton, John Klier, Sonu Kizhakkepura, Nimesha Ratnatunge, University of Massachusetts Amherst, Amherst, MA, USA
841. 4D Tissue Engineering via Cell Traction Force-Mediated Shape Morphing in Single Layer Degradable Hydrogel Scaffolds, Kaelyn Gasvoda, David Cleveland, Aixiang Ding, Eben Alsberg, University of Illinois at Chicago, Chicago, IL, USA
842. Rheological Study on Chitosan-Based Self-Healing Polymer Composite for Biomedical Applications, Hamid Hamedi1, Vahid Rahmanian2, Alan Tonelli, PhD1, Martin King, PhD1,3, 1North Carolina State University College of Textiles, Raleigh, NC, USA, 2North Carolina State University, Department of Chemical and Biomolecular Engineering, Raleigh, NC, USA, 3Donghua University, Shanghai, China
843. Tricolor Visible Wavelength-Selective Hydrogels for Cell Encapsulation and Release, Teresa Rapp, PhD, Cole DeForest, PhD, University of Washington, Seattle, WA, USA
Surface Characterization and Modification (SIG)
844. A Chip-Based Biosensor for Detecting Cortisol Biomarker, Kenneth Alexander, Lauren Bell, Guigen Zhang, PhD, Xiang-An Li, PhD, University of Kentucky, Lexington, KY, USA
845. Antibacterial behavior and Osteoblast response of Optimized Polyaniline-Doped Titanium Oxide Surfaces, Mary Carr1, Sheetal Chowdhury1, Amol Janorkar1, Mary Marquart1, Jason Griggs1, Joel Bumgardner2, Michael Roach1, Aya Ali1, 1University of Mississippi Medical Center, Jackson, MS, USA, 2University of Memphis, Memphis, TN, USA
846. PEG-Norbornene Polycaprolactone Blends for Covalent Peptide Photopatterning, Mohammed Mehdi Benmassaoud1, Nikolas Belanger1, Mulan Tang2, Michael Deleg1, Vince Beachley1, Sebastian Vega1, 1Rowan University, Glassboro, NJ, USA, 2The University of Oklahoma, Norman, OK, USA
847. The influence of incorporation of laminin peptide sequences on integrin activation and focal adhesion formation, Narges Yazdani, Rebecca Willits, PhD, Northeastern University, Boston, MA, USA
848. Increased Initiator Density using Plasma Polymerized Bromoesters for Grafting Zwitterionic Polymer Brushes, Prabhleen Kaur1, Justin Casebier2, Ravi Balasubramanian2, Buddy Ratner1, 1University of Washington, Seattle, WA, USA, 2Oregon State University, Corvallis, OR, USA
849. High resolution chemical surface imaging for the characterisation of biomaterials, Nicholas Farr, BSc, LLB, PhD1, Antje Quade, PhD2, Jan Schafer, PhD2, Cornelia Rodenburg, PhD1, 1University Of Sheffield, Sheffield, United Kingdom, 2Leibniz Institute for Plasma Science and Technology, Greifswald, Germany
850. Design of Personalized Shape-Morphing Stents Using Auxetic - Non-Auxetic Metastructures, Yusuf Dikici1,2, Ozan Akkus, PhD1, 1Case Western Reserve University, Cleveland, OH, USA, 2Bartin University, Bartin, Turkey
Synthetic Scaffolds with Nature-Inspired Functional Groups
851. Hyaluronic Acid Binding Peptide Mediated Directed ECM Assembly to Prevent Fibrotic Capsule Formation, Beth Blake, BS1, Lys Sprenger, BS, MS2, Tugba Ozdemir, BS, MS, PhD1, Klaus Rischka, BS, PhD2, 1South Dakota School of Mines and Technology, Rapid City, SD, USA, 2Fraunhofer Institute for Manufacturing Technology and Advanced Materials - IFAM, Bremen, Germany
Tissue Engineering (SIG)
853. Investigating the Role of Osteoclasts in Bone Tissue Engineering via nCP-Hydrogel Scaffolds, Erfan Jabari1,2, Robert Choe1,2, Mary Sherry1,2, John Osbourne1,2, John Fisher1,2, 1University of Maryland, College Park, College Park, MD, USA, 2Center for Engineering Complex Tissues, College Park, MD, USA
854. Computational Investigation of Material Selection and Interface Layer Height of Multi-layered Scaffolds for Osteochondral Tissue Regeneration, Eoin Devoy, Robert Choe, DM, MSc, John Fisher, PhD, John Osborne, Mary Sherry, University of Maryland, College Park, College Park, MD, USA
855. Assessing Permittivity Frequency Response in GelMA/NaCl Hydrogels for Dielectrically Accurate Tissue Phantoms, Blake Kuzemchak1,2, Robert Choe1,2, Mary Sherry1,2, John Osborne1,2, John Fisher1,2, 1University of Maryland, College Park, MD, USA, 2Center for Engineering Complex Tissues, College Park, MD, USA
856. Tuning Matrix Stress Relaxation in PEG-HA Hydrogels to Regulate the Spreading and Nascent Protein Deposition of Mesenchymal Stromal Cells, Alexandra Borelli1,2, Mark Young1,2, Sarah Mellett1, Michael Blatchley1,2, Varsha Rao1,2, Kristi Anseth1,2, 1University of Colorado Boulder, Boulder, CO, USA, 2BioFrontiers Institute, Boulder, CO, USA
857. Gelatin Maleimide Microdroplets for Hematopoietic Stem Cell Culture in Granular Hydrogels, Gunnar Thompson1, Aidan Gilchrist, PhD2, Brendan Harley, ScD1, 1University of Illinois at Urbana-Champaign, Urbana, IL, USA, 2Stanford University, Stanford, CA, USA
858. Development of a Hydrogel-Based Cellular Model of Vocal Fold Lamina Propria, Xiaoyu Zou1, He Zhang1, Hanyuan Gao1, Oliva George1, Joseph Fox2, Xinqiao Jia1,3, 1Department of Materials Science and Engineering, Newark, DE, USA, 2Deparment of Chemistry and Biochemistry, Newark, DE, USA, 3Department of Biomedical Engineering, Newark, DE, USA
859. Chondrogenesis of mesenchymal stem cells using electrospinning, Nasim Nosoudi, Christoph Hart, Ian Mcknight, Regan Raines, Marshall university, Huntington, WV, USA
860. Injectable porous biorthogonal click chemistry cement for bone tissue engineering, Xifeng Liu, PhD, Lichun Lu, PhD, Mayo Clinic, Rochester, MN, USA
861. Electrospun Poly(* -caprolactone)-Silk Fibroin Scaffold for Vascular Tissue Engineering, Zhongkui Hong, Alex RIckel, University of South Dakota, Sioux Falls, SD, USA
Translation of Tissue Engineering for Cardiovascular Applications
862. Minimally Invasive Delivery of Mesenchymal Stem Cells by Intrapericardial Hydrogel Injection for Cardiac Repair, Junlang Li1,2, Ke Cheng, PhD1,2, 1North Carolina State University, Raleigh, NC, USA, 2North Carolina State University & University of North Carolina at Chapel Hill, Raleigh, NC, USA
863. Hyaluronan and Elastin-Like Protein (HELP) Gels Significantly Improve Cargo Retention in the Myocardium, Meghan Hefferon1, Riley Suhar, PhD1, Vanessa Doulames, PhD1, Yeuming Liu1, Oscar Figueroa, III, Hana Buabbas1, Sarah Heilshorn, PhD1, 1Stanford University, Stanford, CA, USA