Con-current Oral Abstract Presentations Session VII

Biomaterials and Microscale Technologies for Biomedical Applications IV (General Session)


Application of Electrospinning to Produce Hybrid Nanofibrous Scaffolds for Tissue Engineering

A. K. Moghe, B. S. Gupta, M. W. King;
North Carolina State University, Raleigh 27695-8301, NC.


Fibrinolytic Surface by Immobilization of Lysine on Polyurethane through a PEG Spacer

H. Chen1, X. Hu1, D. Li1, Y. Zhang1, W. G. McClung2, J. L. Brash2;
1Wuhan University of Technology, Wuhan, CHINA, 2McMaster University, Hamilton, ON, CANADA.


Surface Engineering in Microfluidic Devices for the Isolation of Smooth Muscle Cells and Endothelial Cells

S. K. Murthy1, B. Plouffe1, M. Radisic2;
1Northeastern University, Boston, MA, 2University of Toronto, Toronto, ON, CANADA.


Remodelling of an Endothelialized Modular Construct In Vivo

R. Gupta, M. V. Sefton;
University of Toronto, Toronto, ON, CANADA.


Multivalent Sonic Hedgehog as an Enhanced Potency Biomaterial Modification for Angiogenesis

S. T. Wall, K. Saha, D. V. Schaffer, k. E. Healy;
UC Berkeley, Berkeley, CA.


Aligned poly(ε-caprolactone) nanowire/fiber arrays: properties for drug delivery and control of cellular interactions

S. L. Tao, T. A. Desai;
UCSF, San Francisco, CA.


Protein Loading on Porous Hydroxyapatite/Poly(lactide-co-glycolide) Scaffolds for Bone Tissue Engineering

E. K. Cushnie, C. T. Laurencin;
University of Virginia, Charlottesville, VA.


Simutaneous Deposition of Human Endothelial Cells and Materials for Fabrication of Vascular Channels

X. Cui, N. Flohr, T. Boland;
Clemson University, Clemson, SC.

Advances in Drug Delivery II (General Session)


Pulsatile Release of PTH for Osteoporosis Treatment

X. Liu, G. J. Pettway, L. K. McCauley, P. X. Ma;
University of Michigan, Ann Arbor, MI.


Growth Hormone Release from pH-Sensitive Complexation Hydrogels

D. A. Carr, M. C. Boudes, O. Z. Fisher, N. A. Peppas;
The University of Texas at Austin, Austin, TX.


Synthesis and Characterization of a Temperature- and pH-responsive Sol-gel Hydrogel Suitable for Drug Delivery

J. C. Garbern, A. S. Hoffman, P. S. Stayton;
University of Washington, Seattle, WA.


Affinity Hydrogels for Sustained Protein Delivery

C-C. Lin, A. T. Metters;
Clemson University, Clemson, SC.


Oligo(trimethylene carbonate) For Vascular Endothelial Growth Factor Delivery

L. Timbart, R. Chapanian, M. Tse, S. Pang, B. Amsden;
Queen's University, Kingston, ON, CANADA.


Polyketal Copolymers: Acid Sensitive Biodegradable Polymers with Tunable Hydrolysis Rates for Drug Delivery

S. C. Yang, N. Murthy;
Georgia Institute of Technology, Atlanta, GA.


Modification of Protein with Polymer-Bisphosphonate Ligand to Increase Bone Affinity

S. Zhang, J. E. I. Wright, H. Uludag;
University of Alberta, Edmonton, AB, CANADA.


Analyzing Intratumoral Chemotherapeutic Drug Penetration in Ablated Tumors Using Finite Element Methods

R. B. Patel1, B. D. Weinberg1, J. Gao2, A. A. Exner1, G. M. Saidel1;
1Case Western Reserve University, Cleveland, OH, 2University of Texas Southwestern Medical Center, Dallas, TX.

Orthopedic SIG: Cell/Tissue Interactions (General Session)


Self-assembled and Nanostructured Hydrogel Scaffolds as New Bone Substitutes

L. Zhang1, S. Ramsaywack2, H. Fenniri3, T. J. Webster1;
1Brown University, Providence, RI, 2University of Alberta, Edmonton, AB, CANADA, 3National Institute for Nanotechnology and University of Alberta, Edmonton, AB, CANADA.


RGD Inhibits Osseointegration of Hydroxyapatite Implants

K. M. Hennessy, W. C. Clem, S. L. Bellis;
University of Alabama at Birmingham, Birmingham, AL.


Microstructured Ti-6Al-4V Surface Improves Osseointegration: an in Vitro and in Vivo Study

Z. Schwartz1, G. Zhao2, P. Raz1, Y. Barak3, M. Tauber4, B. D. Boyan2;
1Hebrew University Hadassah, Jerusalem, ISRAEL, 2Georgia Institute of Technology, Atlanta, GA, 3Impliant Inc., Jerusalem, ISRAEL, 4Arkade Klinik, Breitungen, GERMANY.


Polymer-Ceramic Composite Induces Osteogenesis of Human Mesenchymal Stem Cells

N. L. Leong, J. Jiang, N. N. Okoh, H. H. Lu;
Columbia University, New York, NY.


Characterization of Aggrecan Retention in Fumarate-Based Hydrogels for Orthopaedic Tissue Engineering

K. S. Brink, J. J. Lim, J. D. Weaver, D. M. Doroski, J. S. Temenoff;
Georgia Tech and Emory Unversity, Atlanta, GA.


Cellular Evaluation of Bone Morphogenetic Protein-Derived Oligo-peptides as Candidate Biomolecules for Surface Modified Scaffolds in Bone Tissue Engineering

D. A. Lee1, C. T. Laurencin2;
1Drexel University, Philadelphia, PA, 2University of Virginia, Charlottesville, VA.


Effect of rapidly resorbable calcium-alkali-orthophosphate bone substitute materials on osteogenesis and osteoblastic phenotype expression in vivo

C. Knabe1, G. Berger2, R. Gildenhaar2, C. Koch1, S. Jonscher1, A. Rack3, H. Seligmann1, M. Stiller1;
1Charite University Medical Center, Berlin, GERMANY, 2Federal Institute for Materials Research and Testing, Berlin, GERMANY, 3Helmholtz Research Center Karlsruhe, Karlsruhe, GERMANY.


Ex Vivo Gene Therapy in Combination with a Novel Tubular Sintered Microsphere Scaffold: The In Vivo Delivery of BMP-2 Producing Cells

M. D. Kofron1, J. Li1, K. Martin2, S. G. Kumbar1, A. Adeniran3, X. Wen4, C. T. Laurencin1;
1University of Virginia, Charlottesville, VA, 2Medical University of South Carolina, Charleston, SC, 3University of Maryland, College Park, MD, 4Clemson University, Clemson, SC.

Polysaccharide-based Biomaterials II (General Session)


IGF-1-Induced Elastin Synthesis and Cross-linking by Vascular Smooth Muscle Cells is Mediated by HA-Fragments

C. Kothapalli, A. Ramamurthi;
Clemson University, Charleston, SC.


Concomitant Delivery of Copper Nanoparticles and Hyaluronan Benefits Vascular Elastin Matrix Synthesis, Crosslinking and Fiber Formation

C. Kothapalli, A. Ramamurthi;
Clemson University, Charleston, SC.


Recruitment of Endogenous Stem Cells for Tissue Repair

J. Zhao1, N. Zhang1, A. Scott2, G. D. Prestwich3, X. Wen1;
1Clemson University, Charleston, SC, 2Glycosan BioSystems Inc., Salt Lake City, UT, 3University of Utah, Salt Lake City, UT.


Chemically Modified Light-curable Chitosans with Enhanced Potential in Bone Tissue Engineering

Y. Qiu1, N. Zhang1, Q. kang2, Y. An2, X. Wen1;
1Clemson University, Charleston, SC, 2Medical University of South Carolina, Charleston, SC.


Immobilized Glycosaminoglycans Modulate Proliferation and Organization of Cultured Cholangiocytes

L. Chen, H. W. T. Matthew;
Wayne State University, Detroit, MI.


Introduction of Secondary and Tertiary Amines to Chitosan: Enhancing Delivery of Nucleic Acids

B. Ghosn, K. Roy, S. P. Kasturui, H. Abdul-Razzak;
University of Texas at Austin, Austin, TX.


Design of Polysaccharide Gel-Based Sensor to Quantify the Number of Receptor-Adhesion Ligand Bonds

H. Kong, N. Huebsch, D. Mooney;
Harvard University, Cambridge, MA.


Regulation of Osteogenic and Chondrogenic Differentiation of MSCs in Extracellular Matrix-Hydrogels

N. S. Hwang, S. Varghese, H. Li, A. Canver, J. Elisseeff;
Johns Hopkins University, Baltimore, MD.

Controlled Interactions of Proteins and Peptides with Biomaterial Surfaces (Symposium)


Recombinant Multimeric Integrin Ligands to Convey Integrin Specificity and Clustering

T. A. Petrie, A. J. Garcia;
georgia institute of technology, atlanta, GA.


Fibrin delivery of molecular variants of Synergy and RGD containing fibronectin domains that provide
integrin-specific instructions to mesenchymal stem cells

M. Martino1, M. Mochizuki1, M. Smith2, S. A. Rempel3, J. A. Hubbell1, T. H. Barker4;
1Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, SWITZERLAND, 2Swiss Federal Institute of Technology Zurich (ETHZ), Lausanne, SWITZERLAND, 3Hermelin Brain Tumor Center, Henry Ford Hosp., Detroit, MI, 4H. Coulter Dept. of Biomedical Engineering, Georgia Inst. of Technology, Atlanta, GA.


Cytokine Expression from Monocytes/Macrophages response to Ti-particles and discs

D. H. Kim1, M. Novak1, J. Wilkins2, A. Saywer2, W. M. Reichert1;
1Duke university, Durham, NC, 2BD Technologies, RTP, NC.


Molecular Dynamics Simulations of Peptide Interactions with a Poly-L-Lactic Acid Surface

C. P. O'Brien;
Clemson University, Clemson, SC.


pH Dependence of Albumin Spatial Distribution on a Patterned PS/PMMA Surface

L. Li1, J. L. Brash1, A. P. Hitchcock1, A. Scholl2, A. Doran2;
1McMaster University, Hamilton, ON, CANADA, 2Advanced Light Source, Berkeley, CA.


Comparison of Solvation-Effect Methods for the Simulation of Peptide-Hydrophobic Surface Interactions

R. A. Latour, Y. Sun, B. N. Dominy;
Clemson University, Clemson, SC.


Protein Patterns at the Micro- and Nanoscale by Oxime Bond Formation

H. D. Maynard, K. L. Christman, R. M. Broyer, Z. P. Tolstyka, E. Schopf, Y. Chen;
University of California Los Angeles, Los Angeles, CA.


Investigation of Surface Hydrolysis in Thin Organic Films Using Time-of-Flight Secondary Ion Mass Spectrometry and Principal Component Analysis

F. Cheng1, L. J. Gamble2, D. W. Grainger3, D. G. Castner2;
1National ESCA and Surface Analysis Center For Biomedical Problems, Department of Chemical Engineering, University of Washington, Seattle, WA, 2National ESCA and Surface Analysis Center For Biomedical Problems, Departments of Chemical Engineering and Bioengineering, University of Washington, Seattle, WA, 3Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT.