Abstracts
Advancing Discoveries from the Laboratory to the Clinic
2008 Conference Information
Conference Info
Presentations
Clinical Application Session 1: What is the State of the Stent?
1. Physical Characterization of XIENCE™ V Drug Eluting Stent Coating F-W. Tang1, S. Pacetti2, N. Ding2, T. Glauser2, S. Hossainy2; 1Abbott Vascular, Temecula, CA, 2Abbott Vascular, Santa Clara, CA.
2. Selenium-Derivatized Polyurethanes - Potential Nitric Oxide Generating Coatings for Stents and Other Biomedical Devices B. Wu, M. E. Meyerhoff; - University of Michigan, Ann Arbor, MI.
3. In vivo suppression of restenosis in rat abdominal aorta by nitric oxide-eluting stents M. M. S. Simões, F. G. de Oliveira, G. Barreto, A. B. Seabra, M. G. de Oliveira; State University of Campinas, Campinas, BRAZIL.
4. Ultra-thin non-polymeric coatings for DES D. Hakimi1, M. Landy1, M. Tsui1, M. Chen1, A. Abizaid2, R. Bonan3; 1Miv Therapeutics, Vancouver, BC, CANADA, 2Institute Dante Pazzanese of Cardiology, Sao Paulo, BRAZIL, 3Montreal Heart Institute, Montreal, QC, CANADA.
5. Biocompatibility of Therapeutic Self-Assembled Monolayers for Drug-Eluting Coronary Stents G. Mani1, B. Chandrasekar2, D. M. Johnson1, M. Feldman2, D. Patel2, C. M. Agrawal1; 1The University of Texas at San Antonio, San Antonio, TX, 2The University of Texas Health Science Center at San Antonio, San Antonio, TX.
6. Comparing Endothelial Cell Function on Self-Assembled Type IV Collagen and Its Components A. P. Wagner, C. M. Yoder, K. N. Kader; The University of Iowa, Iowa City, IA.
Clinical Application Session 2: Ocular Comfort and Drug Delivery
7. Challenges, Opportunities, and New Directions in Conventional and Silicone Hydrogel Contact Lens Polymers Lynn Winterton, CIBA Vision Corporation, Duluth, GA.
8. Microneedles for Ocular Drug Delivery S. R. Patel1, J. Jiang1, H. S. Gill1, D. Ghate2, B. E. McCarey2, D. H. Geroski2, J. Nickerson2, H. F. Edelhauser2, M. R. Prausnitz1; 1Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA.
9. Hydrophobic Domains in Silicone Hydrogel Contact Lenses J. Jacob1, T. Edwards2, K. Kura2, D. Nissanke3, H. Ketelson3; 1Louisiana State University Health Sciences Center, New Orleans, LA, 2Louisana State University Health Sciences Center, Department of Ophthalmology, New Orleans, LA, 3Alcon Research Laboratories, Fort Worth, TX.
10. Release Studies of Therapeutic Contact Lenses K. Ngo, M. E. Byrne; Auburn University, Auburn, AL.
11. Intraocular Lens Calcification in a Subcutaneous Model R. Jain; Advanced Medical Optics, Inc., Santa Ana, CA.
12. Hydrogels for Sustained Drug Release with Intraocular Lens Implantation for Cataract Surgery S. Garty, R. Shirakawa, J. D. Bryers, B. D. Ratner, T. T. Shen; University of Washington, Seattle, WA.
Clinical Application Session 3: Inflammation and Immunology
13. Soluble Cobalt, Nickel and Co-Cr-Mo alloy particles induce monocyte T-cell costimulatory molecules CD-86, CD54 and pro-inflammatory cytokine secretion. M. S. Caicedo, R. Desai, K. McAllister, J. J. Jacobs, N. J. Hallab; Rush University Medical Center, Chicago, IL.
14. Therapeutic Immune-modulation using siRNA: combinatorial, single carrier delivery of IL-10 silencing siRNA and DNA vaccine A. Singh, H. Nie, K. Roy; The University of Texas at Austin, Austin, TX.
15. Dendritic Cell Arrays for High-Throughput Immuno-Engineering B. G. Keselowsky, A. Acharya, N. Dolgova, M. Clare-Salzler; University of Florida, Gainesville, FL.
16. A Simple High Throughput Approach to Study the Effects of Biomaterials on Dendritic Cell Phenotype P. Kou, J. Babensee; Georgia Institute of Technology, Atlanta, GA.
17. Estimation of Biological Potential and Binding Affinity of Orthopaedic Wear Debris Bound to Different Endotoxins for Aseptic Loosening Pathogenesis Study H-N. Hao, B. Zhen, N. Abdel-Haq, S-Y. Yang, H. Pierre-Jacques, L. G. Morawa; Wayne State Universtiy, Detroit, MI.
18. A Novel MMP-Inhibiting Wound Dressing Reduces MMP activity in human chronic wounds A. L. Brown1, R. L. Ho1, C. E. Hamer1, G. A. Skarja1, P. Coutts2, G. Sibbald2, M. H. May1, M. V. Sefton1; 1Rimon Therapeutics Ltd, Toronto, ON, CANADA, 2Women’s College Hospital, Toronto, ON, CANADA.
Clinical Application Session 4: Spine and Nerve Repair
19. Wear Performance of Metal-On-Metal and Metal-On-Polyethylene Lumbar Disc Replacements under ISO and Walking Conditions T. Uth1, M. Wimmer1, Y. Dwivedi1, P. Pare2, F. Chan2; 1Rush University Medical Center, Chicago, IL, 2Medtronic Sofamor Danek USA, Inc., Memphis, TN.
20. Viscosity of injectable two-solution bone cements prepared with cross-linked PMMA poly (methyl methacrylate) microspheres and nanospheres for use in percutaneous kyphoplasty and vertebroplasty D. B. C. Rodrigues, J. M. Hasenwinkel; Syracuse University, Syracuse, NY.
21. Bioactive Nanostructured Materials for Neural Interfaces M. Abidian, D. C. Martin, D. R. Kipke; University of Michigan, Ann Arbor, MI.
22. Acetylcholine-based biomaterial enhances neuronal differentiation J. Gao, C. Gumera, Y. Wang; Georgia Institute of Technology/Emory University, Atlanta, GA.
23. Surface modification of poly(lactic acid)-based nerve conduit with oligo(lactic acid)- oligo peputide amphiphilic conjugates T. Yamaoka; National Cardiovascular Center Research Institute, Suita, JAPAN.
24. Nanodevices For Treatment of Secondary Spinal Cord Injury V. Reukov, R. Satishkumar, A. Vertegel; Clemson University, Clemson, SC.
Technology Rapid Fire 1: Biomaterials for Nanomedicine: From Bench to Bed
43. Top-down Fabrication of Uniform Non-Spherical Polymer Particles for Nanomedicine Applications W. Hu, F. Buyukserin, A. Crouch, L. Tao, X-M. Zhao, J. Gao; University of Texas at Dallas, Richardson, TX.
44. Engineering thermo-responsive NanoSuitcases D. Cohn, A. Benyamin, H. Sagiv, G. Lando; The Hebrew University Of Jerusalem, Jerusalem, ISRAEL.
45. Fabrication of Shape-Specific, Enzymatically-Triggered Nanoparticles using Nano Imprint Lithography M. E. Caldorera-Moore, L. Shi, K. Roy; University of Texas at Austin, Austin, TX.
46. A novel nanoscale probe facilitates non-invasive quantification of tumor EPR status and helps predict chemotherapy outcomes in a rodent breast cancer model R. Bellamkonda1, A. Annapragada2, E. Karathanasis1; 1Georgia Institute of Technology/ Emory University, Atlanta, GA, 2Georgia Institute of Technology/Emory University, GA.
47. Systemic targeted siRNA delivery with a multifunctional carrier Z-R. Lu; University of Utah, Salt Lake City, UT.
48. Assessment of Carbon Nanotube Toxicity using 3D Protein Matrices M. Kariolis, J. P. Stegemann; Rensselaer Polytechnic Institute, Troy, NY.
49. Benefits of controlled copper ion delivery from copper nanoparticles (CuNP) to elastin matrix synthesis & maturation A. Ramamurthi, C. R. Kothapalli; Clemson University, Charleston, SC.
50. Multiwalled Carbon Nanotubes Grown from Anodized Titanium for Sensing New Bone Growth S. Sirivisoot, T. J. Webster; Brown University, Providence, RI.
51. Controlling Osteoblast Function on Nano Rough Micron Patterned Titanium S. D. Puckett, T. J. Webster; Brown University, Providence, RI.
52. Versatile Scaffolds of Nanowires on Ti for Smart Bone Implants and Stents R. Tian; University of Arkansas, Fayetteville, AR.
Technology Rapid Fire 2: Cell-interfacing Technologies
53. Tethered Epidermal Growth Factor Increases Multipotent Stromal Cell Proliferation and Differentiation on Ligand-Coated Scaffolds M. O. Platt, A. J. Roman, D. A. Lauffenburger, L. G. Griffith; Massachusetts Institute of Technology, Cambridge, MA.
54. Integrin 2 Signaling is Important in the Production of Angiogenic Growth Factors by Osteoblasts in Response to Titanium Surface Microstructure A. L. Raines1, J. Lee1, R. Olivares-Navarrate1, M. Wieland2, Z. Schwartz1, B. D. Boyan1; 1Georgia Institute of Technology, Atlanta, GA, 2Institut Straumann, Basel, SWITZERLAND.
55. BioArtificial Matrices to Promote Vascular Network Formation E. A. Phelps, A. J. García; Georgia Institute of Technology, Atlanta, GA.
56. Analyzing and Protecting the Conformation and Orientation of Immobilized Proteins L. Gamble, F. Cheng, D. G. Castner; University of Washington, Seattle, WA.
57. An Artificial Tendon with Durable Muscle Interface D. Melvin1, A. Litsky2, J. Mayerson2, D. Witte3, N. Juncosa-Melvin1, D. B. Melvin1; 1Surgical Energetics, Inc.;Cincinnati, OH, 2Ohio State University, Columbus, OH, 3Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.
58. Modulating the macrophage foreign body response through controlled adhesion to surfaces using fibrinogen-derived peptides R. E. Whitmire, A. W. Bridges, T. Bonhivert, L. A. Lyon, A. J. Garcia; Georgia Institute of Technology, Atlanta, GA.
59. Platelets adhesion on functionalized nonwoven fiber vascular grafts M. Maire1, G. Diaz-Quijada2, L. Robitaille2, Y. Merhi3, L. Yahia1, A. Ajjii2, M. Bureau2; 1Ecole Polytechnique de Montréal, Montréal, QC, CANADA, 2National Research Council Canada, Boucherville, QC, CANADA, 3Montreal Heart Institute, Montréal, QC, CANADA.
60. PEGDA Hydrogels with Patterned Elasticity for the Study of Cell Response to Substrate Stiffness S. Nemir, M. K. McHale, J. L. West; Rice University, Houston, TX.
61. Modulation of Cellular Adhesion by Changing Substrate Thickness and Adhesive Peptide Concentration D. Doroski1, B. Nguyen2, J. Temenoff1; 1Georgia Institute of Technology and Emory University, Atlanta, GA, 2Georgia Institute of Technology, Atlanta, GA.
62. How do cells translate biomaterial properties into changes in gene expression? M. R. Caplan, M. M. Shah, B. G. Kelso, V. Shankarraman; Arizona State University, Tempe, AZ.
Moderated Poster Session A
83. Peripheral Nerve Regeneration Through Structurally Modified Acellular Scaffolds in a Rabbit Model P. Sierpinski, J. Burnell, J. Yoo, A. Atala, M. Van Dyke; Wake Forest University, Winston-Salem, NC.
84. Osteoblast Responses to Titanium Surface Microstructure and Surface Energy are Donor Age Dependent Z. Schwartz1, R. Olivares-Navarrete1, D. L. Cochran2, S. Hyzy1, C. Erdman1, M. Wieland3, B. D. Boyan1; 1Georgia Institute of Technology, Atlanta, GA, 2University of Texas Health Science Center at San Antonio, San Antonio, TX, 3Institut Straumann, Basel, SWITZERLAND.
85. Reference Scaffolds for Tissue Engineering C. G. Simon, Jr., J. Sun, M. T. Cicerone; NIST, Gaithersburg, MD.
86. Modulating macrophage response to wear particles to mitigate per-implant osteolysis T. Zaveri, N. Dolgova, M. Clare-salzler, B. Keselowsky; University of Florida, Gainesville, FL.
Moderated Poster Session B
87. Surface modification of electrospun nanofibers via blending: Controlling hydrophobicity/hydrophilicity for protein adsorption R. Vasita, D. S. Katti; Indian Institute of Technology Kanpur, Kanpur, INDIA.
88. Selectively Degradable Hydrogels for Investigating Cell-Cell Interactions in Coculture A. Ribeiro1, F. Maia1, O. Yasar2, B. Starly2, J. B. Leach1; 1University of Maryland, Baltimore County, Baltimore, MD, 2University of Oklahoma, Norman, OK.
89. Photo-initiated Grafting of N-maleic acyl-chitosan Enhances Endothelial Cell Adhesion and Function on PLA Surface F. Zhao1, A. Zhu2, T. Ma3; 1Duke University, Durham, NC, 2Yangzhou University, Yangzhou, CHINA, 3Florida State University, Tallahassee, FL.
90. Superacidity of Hydroxyl Functionalized Polytetrafluoroethylene B. Krawczyk1, C. M. Yoder1, J. Baltrusaitis1, T. G. Vargo2, K. N. Kader1; 1The University of Iowa, Iowa City, IA, 2Integument Technologies, Inc., Tonawanda, NY
Clinical Application Session 5: Current and Future Strategies for Repair and Replacement of Hard Tissues
25. Dermal Barriers to Prevent Infection of Percutaneous Implants D. Isackson1, B. Bailey2, N. A. Brown1, C. Petti1, K. N. Bachus1; 1University of Utah, Salt Lake City, UT, 2Bone and Joint Research Laboratory, Salt Lake City, UT.
26. Analysis of Bone Marrow Aspirate as an Osteoinductive Bone Graft Material S. S. Kay1, K. Jeray2, S. Tanner2, K. J. L. Burg1; 1Clemson University, Clemson, SC, 2Greenville Hospital Systems, Greenville, SC.
27. Collagen-mimetic Scaffold Coating Enhances Healing of Critically-Sized Bone Defects A. M. Wojtowicz1, M. E. Oest1, K. M. Dupont1, K. L. Burns1, D. W. Hutmacher2, R. E. Guldberg1, A. J. Garcia1; 1Georgia Institute of Technology, Atlanta, GA, 2Queensland University of Technology, Brisbane, AUSTRALIA.
28. Biodegradable nanofibrous multilayer composite scaffolds as 3D supports for the osteogenic differentiation of bone marrow mesenchymal cells under dynamic conditions M. T. Rodrigues, A. Martins, A. C. Guimarães, J. V. Araújo, M. E. Gomes, N. M. Neves, R. L. Reis; University of Minho, Braga, PORTUGAL.
29. Effect of water on photopolymerization and properties of dentin adhesives with branched methacrylate P. Spencer1, Q. Ye1, J. Park1, A. Misra1, E. M. Topp1, E. L. Kostoryz2, Y. Wang2; 1University of Kansas, Lawrence, KS, 2University of Missouri-Kansas City, Kansas City, MO.
30. Dickkopf-2 (Dkk2) is Required for Osteoblast Terminal Differentiation on Titanium Microstructured Surfaces R. Olivares-Navarrete1, S. Hyzy1, P. Raz2, M. Wieland3, B. D. Boyan1, Z. Schwartz1; 1Georgia Institute of Technology, Atlanta, GA, 2Hebrew University, Jerusalem, Israel, 3Institut Straumann AG, Basel, Switzerland.
Technology Rapid Fire 3: Tissue Engineering Strategies
63. Efficacy of induction of aneurysmal cell-mediated elastin regeneration for stabilizing aortic aneurysms A. Ramamurthi, C. E. Gacchina, C. R. Kothapalli, N. R. Vyavahare; Clemson University, Charleston, SC.
64. A micron scale three dimensional scaffold for colon epithelial intestinal tissue engineering R. Majani; University of Nottingham, Nottingham, UNITED KINGDOM.
65. Oxygen Generating Biomaterials for Three-Dimensional Cell Growth C. L. Ward, S. Oh, A. A. Atala, J. J. Yoo, B. S. Harrison; Wake Forest University, Winston Salem, NC.
66. Localized, Sustained Nonviral Gene Delivery from Alginate Hydrogels for Osteogenesis M. D. Krebs, E. Salter, E. Chen, K. A. Sutter, E. Alsberg; Case Western Reserve University, Cleveland, OH.
67. Use of novel fibrin-binding peptides as a delivery vehicle for proteins into fibrin matrices A. Soon, S. E. Stabenfeldt, T. H. Barker; Georgia Institute of Technology, Atlanta, GA.
68. Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs A. Khademhosseini, E. Lo, Y. Du, S. Ali; Harvard-MIT, Cambridge, MA.
69. VEGF-mediated Tubulogenesis in Three-Dimensional Collagenase-degradable PEGDA Hydrogels J. E. Leslie, J. J. Moon, J. L. West; Rice University, Houston, TX.
70. Microfluidic Hydrogels for Microvascular Tissue Engineering A. P. Golden, J. Tien; Boston University, Boston, MA.
71. Spatial control of mES cell differentiation within microsphere based scaffolds A. E. Olaye, L. Buttery, F. Rose, K. Shakesheff; University of Nottingham, Nottingham, UNITED KINGDOM.
72. Microsphere-Mediated Delivery of Retinoic Acid within Embryoid Bodies Directs Embryonic Stem Cell Differentiation R. L. Carpenedo, S. A. Seaman, T. C. McDevitt; Georgia Institute of Technology, Atlanta, GA.
Technology Rapid Fire 4: Novel Biomaterials
73. A New Reactive Oxygen Species Sensitive Delivery Vehicle for Targeting Oxidative Stress D. S. Wilson, N. Murthy; Georgia Institute of Technology, Atlanta, GA.
74. Creating waved and aligned nanofiber composites to mimic the microstructure and match the compliance of blood vessels V. Z. Beachley; Clemson, Charleston, SC.
75. Degradation and Cytocompatibility of a Mixed-Mode Fumarate/Dithiol PEG-based Hydrogel K. S. Brink, J. S. Temenoff; Georgia Institute of Technology, Atlanta, GA.
76. Novel Carboxymethylcellulose-Derived Hydrogel Prevents Postoperative Adhesions in an Objective Rat Model M. ITO, N. ENDO, H. KANEKO; Innovation Research Institute, Hino, Tokyo, JAPAN.
77. Derivation of Embryonic Acellular Matrices from Stem Cells via Mechanical Acellularization Techniques A. V. Ngangan, J. Waring, T. C. McDevitt; Georgia Institute of Technology, Atlanta, GA.
78. Synthesis, characterization and antibacterial activity of nitric oxide-releasing poly(nitrosated) polyester/poly(methylmetacrylate) films A. B. Seabra1, D. Martins2, R. da Silva1, M. M. G. Simões1, M. Brocchi2, M. G. de Oliveira1; 1Chemistry Institute - Universidade Estadual de Campinas, Campinas, BRAZIL, 2Genomic and Bacterial Molecular Biology Laboratory, Institute of Biology- Universidade Estadual de Campinas, Campinas, BRAZIL.
79. Effect of Chemistry and Crosslinking Density on Thermo-Mechanical Properties of (Meth)acrylate Shape-Memory Polymer Networks D. Safranski, K. Gall; Georgia Institute of Technology, Atlanta, GA.
80. Nitrilotriacetic Acid-Nickel Affinity Protein Delivery via Polyketal Microparticles J. C. Sy, N. Murthy, M. E. Davis; Georgia Institute of Technology & Emory University, Atlanta, GA.
81. Bacterial Adhesion to Submicron Textured Biomaterials L. Quinn, K. R. Milner, C. A. Siedlecki; Pennsylvania State University, Hershey, PA.
82. A Keratin Biomaterial Gel Derived from Human Hair is Hemostatic in an Acute Liver Hemorrhage Model - T. Aboushwareb, D. Eberli, C. Ward, C. Broda, A. Atala, M. Van Dyke, L. Burnett; Wake Forest University School of Medicine, Winston Salem, NC.
Moderated Poster Session C
91. Correlation between Photo-Polymerization behavior and Microstructure of Heterogeneous Model Dentin Adhesive Q. Ye1, P. Spencer1, J. Park1, A. Misra1, E. M. Topp1, Y. Wang2; 1University of Kansas, Lawrence, KS, 2University of Missouri-Kansas City, Kansas City, MO.
92. Mechanical Properties of Highly-Crosslinked, Vitamin E Infused GUR1020 and GUR1050 UHMWPE J. Freedman, N. McFarland, D. Schroeder; Biomet Inc., Warsaw, IN.
93. Articular Cartilage Engineering: A comparison of canine and human cells C. W. Ferguson, A. S. Ferng, J. A. Szivek, D. S. Margolis, W. A. Grana; University of Arizona, Tucson, AZ.
94. Fibrochondrogenic Differentiation of hMSCs on Nanofiber Scaffolds with and without Hydroxyapatite Nanoparticles K. L. Moffat1, A. S. P. Kwei1, S. B. Doty2, H. H. Lu1; 1Columbia University, New York, NY, 2Hospital for Special Surgery, New York, NY.
Moderated Poster Session D
95. The Influence of Organized Nanofiber Alignment on the Myotube Formation S. Lee, J. Choi, G. J. Christ, A. Atala, J. J. Yoo; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC.
96. Porous Biomineralized Scaffolds as a 3-D Tissue Culture Systems for Studying Bone Metastasis S. P. Pathi, C. Fischbach-Teschl; Cornell University, Ithaca, NY.
97. Delivery of Pharmaceutical Agents to Orthopedic Defects from Modified Calcium Sulfate Implants J. A. Jennings1, M. Crews1, J. McCanless1, S. Noel1, B. Reves1, T. Watson2, W. Haggard1; 1University of Memphis, Memphis, TN, 2Orthopaedic surgery Department, St. Louis University, St. Louis, MO.
98. Tamoxifen Loaded Polylactide Beads for Breast Tissue Engineering Following Lumpectomy mF. Xu, K. Burg, K. Neser; Clemson University, Clemson, SC.
Clinical Application Session 6: Imaging and Therapeutics Delivery
31. Intratumoral Chemotherapy: from Research to the Clinic for a New Lung Cancer Treatment Paradigm E. P. Goldberg; University of Florida, Mt Dora , FL.
32. beta-Lapachone Polymer Micelles as Novel Nanotherapeutics for Lung Cancer E. Blanco, E. A. Bey, D. A. Boothman, J. Gao; University of Texas Southwestern Medical Center at Dallas, Dallas, TX.
33. Economical Synthesis and Evaluation of Cancer Targeting Constructs J. M. Stukel1, R. C. Li2, H. D. Maynard2, M. R. Caplan1; 1Arizona State University, Tempe, AZ, 2University of California, Los Angeles, Los Angeles, CA.
34. Nucleic acid release from carriers via physical and biological triggers M. E. Byrne, S. Venkatesh, J. Wower; Auburn University, Auburn, AL.
35. Polyketal-mediated drug and protein delivery for cardiac regeneration - J. C. Sy1, G. S. Iyer1, S. C. Yang2, S. Dikalov1, N. Murthy2, M. E. Davis1; 1Emory University, Atlanta, GA, 2Georgia Institute of Technology, Atlanta, GA.
36. A new nanosensor for detection of in vivo hydrogen peroxide D. Lee, D. Dasari, N. Murthy; Georgia Institute of Technology, Atlanta, GA.
Clinical Application Session 7: Musculoskeletal Applications
37. Performance of Tibial Bearings Manufactured from Highly-Crosslinked, Vitamin E Infused, UHMWPE J. Freedman, D. Schroeder; Biomet Inc., Warsaw, IN.
38. “Sensate” Cartilage Covered Scaffolds Can Detect Subtle Load Changes In Vivo Following ACL Disruption J. A. Szivek, C. P. Geffre, D. S. Margolis, D. W. DeYoung, J. T. Ruth, D. T. Harris; University of Arizona, Tucson, AZ.
39. Shape Memory Polymers for Soft Tissue Fixation in ACL Reconstruction K. Gall; Georgia Tech, Atlanta, GA.
40. BMP-2 Peptide Grafted to a Degradable Substrate Enhances Osteogenic Differentiation of Stromal Cells J. Ma, X. He, E. Jabbari; University of South Carolina, Columbia, SC.
41. Superswelling and Patterned Dual-Crosslinked Hyaluronic Acid Hydrogels : Zonal Distribution of Hydrogel Properties for Tissue Engineering Applications S. Suri, S. Zawko, Q. Trong, C. E. Schmidt; The University of Texas at Austin, Austin, TX.
42. Artificial Cartilage Replacement - Early Clinical Results D. N. Ku; Georgia Institute of Technology, Atlanta, GA.
Poster Presentations
What is the State of the Stent?
99. Guide Catheter Surface Treatment to Minimize Endovascular Trauma H. Rangwala, A. E. Meyer, S. Rudin, R. E. Baier; University at Buffalo, Buffalo, NY.
100. ExoSeal®: A Novel Bioabsorbable Vascular Closure Device V. Dave, J. Dooley, C. Chen, D. Donohoe; Cordis Corporation, Warren, NJ.
101. Fluorinated diamond-like carbon as a potential coating for reendothelialization of intravascular stent platform S. Nagashima;Keio University, Yokohama, JAPAN.
102. Site-Specific Intimal Wall Forces During Guide and Stent Catheter Navigation R. E. Baier, A. Sengupta, A. E. Meyer, S. Schafer, K. R. Hoffmann, T. Kesavadas; University at Buffalo, Buffalo, NY.
Ocular Comfort and Drug Delivery
103. Withdrawn
104. Polymeric STAR Systems for an Artificial Cornea to Treat Global Blindness S. Garty, R. Shirakawa, B. D. Ratner, T. T. Shen; University of Washington, Seattle, WA.
105. Preparation and Characteristics of Novel Porous PLGA Microsphere by Gas Foaming Method Using Hydrogen Peroxide J. S. Son1, S. Oh2, K. Park1, D. K. Han1; 1Biomaterials Research Center, Korea Institute of Science and Technology, Seoul, REPUBLIC OF KOREA, 2The University of Texas at San Antonio, San Antonio, TX.
Inflammation and Immunology
106. Macrophage Phenotypic Stability During Extended Culture L. M. Chamberlain1, M. Gonzalez-Juarrero2, D. W. Grainger1; 1University of Utah, Salt Lake City, UT, 2Colorado State University, Fort Collins, CO, CO.
107. The role of substrate rigidity in epithelial to mesenchymal transitions (EMT); implications in fibrotic responses m A. E. Carson, J. Chen, T. H. Barker; Georgia Institute of Technology, Atlanta, GA.
108. 3-D Scaffolds for Tissue Engineering with Control of Dendritic Cell Phenotype J. Park, J. Babensee; Georgia Institute of Technology, Atlanta, GA.
109. Multi-Functional Bioscaffolds to Modulate Local Inflammation L. Sun; Carnegie Mellon University, Pittsburgh, PA.
Spine and Nerve Repair
110. Development of Smart Tissue Adhesive for Treatment of Intraoperative Bladder Injury J. Nagatomi, E. Cho, J. Lee, K. Webb; Clemson University, Clemson, SC.
111. Bioprinting Methods to Create an Elastic Lamellar Scaffold for Intervertebral Disc Regeneration B. R. Whatley, Y. Qiu, X. Wen; Clemson- MUSC, Charleston, SC.
112. A New Nitrogen Plasma Implanted Titanium Surface To Inhibit Orthopaedic Related Infection K. Y. Leung1, R. Kao1, P. Chu2, K. Cheung1, K. Luk1, K. Yeung2; 1The University of Hong Kong, Pokfulam, HONG KONG, 2City University of Hong Kong, Kowloon Tong, HONG KONG.
113. Optimization of novel two-solution based bone cements for vertebroplasty and kyphoplasty applications D. B. C. Rodrigues, J. M. Hasenwinkel; Syracuse University, Syracuse, NY.
114. Novel Cell Encapsulation through Co-axial Electrospinning: Mimicking the Natural Tissue R. A. Pareta, T. J. Webster; BROWN UNIVERSITY, PROVIDENCE, RI.
Current and Future Strategies for Repair and Replacement of Hard Tissues
115. A Prolonged Two-Phase Peptide Release Achieved Using Amino- Silane Chemistry Functionalization and Nanocrystalline Hydroxyapatite in a Degradable Polymer Composite H. Liu, T. J. Webster; Brown University, Providence, RI.
116. Composite Materials Consisting of Hydroxyapatite Impregnated Collagen Matrices Affect Osteoblast Behavior B. L. Rogers1, Y. Li2, S. Jee2; 1Georgia Institute of Technology, Atlanta, GA, 2University of Florida, Gainesville, FL.
117. In vitro intracellular signaling studies of calcium phosphate bone grafting materials predict in vivo tissue growth C. Knabe1, M. Stiller1, G. Berger2, R. Gildenhaar2, J. Kim3, I. M. Shapiro4, P. Ducheyne3; 1Charite University Medical Center, Berlin, GERMANY, 2Federal Institute for Materials Research and Testing, Berlin, GERMANY, 3University of Pennsylvania, Philadelphia, PA, 4Thomas Jefferson University, Philadelphia, PA.
118. Use of novel fibrin-binding peptides as a delivery vehicle for proteins into fibrin matrices A. Soon, S. Stabenfeldt, T. H. Barker; Georgia Institute of Technology, Atlanta, GA.
119. 5kDa Component of Enamel Matrix Derivative Possesses Osteogenic Properties R. Olivares-Navarrete1, R. A. Chaudhri1, M. Dard2, M. Wieland2, B. D. Boyan1, Z. Schwartz1; 1Georgia Institute of Technology, Atlanta, GA, 2institut Straumann AG, Basel, Switzerland.
120. Simple Application of Fibronectin-Mimetic Coating Enhances Implant Osseointegration T. A. Petrie, C. D. Reyes, K. L. Burns, A. J. Garcia; Georgia Institute of Technology, Atlanta, GA.
121. Biodegradable Composite Scaffolds for Directing Osteogenesis and Bone Formation K. Leach, J. He, D. Genetos; University of Ca lifornia, Davis, Davis, CA.
122. A Novel Osteostimulatory Resorbable Composite for Orthopaedic Fixation Applications J. J. Cooper1, J. A. Hunt2, A. T. Mackie1; 1Biocomposites Ltd, Staffordshire, UNITED KINGDOM, 2UKCTE University of Liverpool, Liverpool, UNITED KINGDOM.
123. Mechanically-dynamic polymer nanocomposites for intracortical microelectrode substrates J. R. Capadona1, K. Shanmuganathan2, J. P. Harris2, D. J. Tyler2, S. J. Rowan2, C. Weder2; 1L. Stokes Cleveland VAMC, Cleveland, OH, 2Case Western Reserve University, Cleveland, OH.
124. Modulation of Osteogenic and vasculogenic Differentiation of Stromal Cells in a Collagen Scaffold J. A. Henderson, X. He, E. Jabbari; University of South Carolina, Columbia, SC.
125. Novel Bilayered Polymeric Microspheres for Bone Tissue Engineering Applications: Effects of Alginate Coating on Release Kinetics Y. M. Khan, B. Corgiat, K. Ondesko; University of Virginia, Charlottesville, VA.
126. New Generation Calcium Phosphate Bone Cement A. Tofighi; ETEX Corporation, Cambridge, MA.
127. Enhanced Injectability of Self-Setting Calcium Phosphate Cements A. D. Rosenberg, R. Palazzolo, A. Tofighi, J. Chang; ETEX Corporation, Cambridge, MA.
128. Human bone response to CS/PLLA composite S. S. Mamidwar1, R. Horowitz2, J. Ricci3, H. Alexander1; 1Orthogen LLC, Springfield, NJ, 2Private Practice, Scarsdale, NY, 3New York University College of Dentistry, New York, NY.
129. Calcium Phosphate-Containing Scaffolds Stimulate Early Stage Osteogenic Differentiation J. R. Popp1, B. J. Love2, K. E. Laflin1, A. S. Goldstein1; 1Virginia Tech, Blacksburg, VA, 2University of Michigan, Ann Arbor, MI.
130. A novel method to fabricate unidirectional porous hydroxyapatite body using ethanol bubble in a viscous slurry B-T. Lee1, S. Islam1, Y-K. Min2, H-Y. Song3; 1Dept. of Biomedical Engg. & Materials, Soonchunhyang Univerisity, Cheonan, South Korea, Cheonan, Republic of Korea, 2Dept. of Physiology, Soonchunhyang Univerisity, Cheonan, South Korea, Cheonan, Republic of Korea, 3Dept. of Microbiology, Soonchunhyang Univerisity, Cheonan, South Korea, Cheonan, Republic of Korea.
131. Canine Mandibular Augmentation Using Autologous Bone Marrow Stromal Cells M. H. Mankani; UCSF, San Francisco, CA.
132. Fabrication of Calcium Phosphate-Calcium Sulfate Injectable Bone Substitute Using Chitosan and Citric Acid H-Y. Song1, A. H. E. Rahman2, M. A. Jyoti1, J-Y. Mang3, B. Lee2; 1Department of Microbiology, School of Medicine, Soonchunhyang University, cheonan, Republic of Korea, 2Department of Biomedical Engineering & Materials, Soonchunhyang University, cheonan, Republic of Korea, 3Department of Chemistry, Soonchunhyang University, cheonan, Republic of Korea.
133. Surface Characterization of Co-Cr Alloy L605 Electropolishing in 15 vol % Phosphoric Acid H. Aihara, G. S. Selvaduray; San Jose State University, San Jose, CA.
134. Nano-mechanical Characterization of Sea Urchin Teeth: A Comparison Study with Human Teeth S. A. Chowdhury, A. J. Siccardi, S. A. Watts, Y. K. Vohra; University of Alabama at Birmingham, Birmingham, AL.
135. Reverse thermo-responsive polymers for in situ generated implants D. Cohn, A. Sosnik, S. Garty; The Hebrew University Of Jerusalem, Jerusalem, ISRAEL.
136. Direct Observation of the Formation of Collagen at Dental Implant Surfaces L. A. Giannuzzi1, D. Phifer1, N. J. Giannuzzi2, M. J. Capuano3, R. P. Gursky1, L. Pullan1; 1FEI Company, Hillsboro, OR, 2private practice, Miller Place, NY, 3Long Island Oral and Maxillofacial Surgery, Selden, NY.
137. Structural implant concept for buco-maxilo-facial applications T. H. Samed e Sousa, C. A. Fortulan, Sr., E. A. Santos, B. M. Purquerio, Sr.; University of Sao Paulo, São Carlos, BRAZIL.
Imaging and Therapeutics
138. Specificity of multivalent constructs is concentration dependent E. V. Rosca, M. R. Caplan; Arizona State University, Tempe, AZ.
139. Ellagic acid-chitosan based local delivery system has an anti-tumor effect on brain cancer both in vitro and in vivo. - S. Kim, M. Gaber, Y. Yang; University of Tennessee Health Science Center, Memphis, TN.
140. Polyketals: a New Drug Delivery Platform for Treating Acute Liver Failure S. C. Yang1, M. Bhide2, I. N. Crispe2, R. H. Pierce2, N. Murthy1; 1Georgia Institute of Technology, Atlanta, GA, 2University of Rochester, Rochester, NY.
141. Enhanced Mineralization and Vessel Stabilization of a Cranial Defect by Activation of Specific Sphingosine-1-Phosphate Receptors Using Polymer Encapsulated Small Molecule Delivery C. E. Petrie Aronin, L. S. Sefcik, T. L. Macdonald, K. R. Lynch, R. C. Ogle, E. A. Botchwey; University of Virginia, Charlottesville, VA.
142. Polymersomes: Versatile Vesicles for Imaging and Drug Delivery D. H. Levine1, P. P. Ghoroghchian1, J. Freudenberg1, G. Zhang1, G. Li1, K. P. Davis2, F. S. Bates2, M. J. Therien1, R. Murali1, D. A. Hammer1; 1University of Pennsylvania, Philadelphia, PA, 2University of Minnesota, Minneapolis, MN.
143. Biodegradable Self-Assembled Nanoparticles for Targeted Delivery of Paclitaxel to Tumor Cells X. He, A. E. Mercado, W. Xu, E. Jabbari; University of South Carolina, Columbia, SC.
144. The Kinetics of Particle Release from DNA-Linked Multiparticle Drug Delivery Vehicles C. K. Tison, V. T. Milam; Georgia Institute of Technology, Atlanta, GA.
145. A Comprehensive Approach for Real-time Drug Release Imaging from Polymeric Coatings J. Foley1, R. Hoerr1, M. Matuszewski1, J. Puskas2, G. Haugstad3, J. Dong3, C. Frethem3; 1Nanocopoeia, Inc., St. Paul, MN, 2University of Akron, Akron, OH, 3University of Minnesota Characterization Facility, Minneapolis, MN.
146. Nanodevices for Treatment of Hyperlipidemia. V. Reukov, V. Maximov, A. Vertegel; Clemson University, Clemson, SC.
147. Preliminary Investigation of Lyophilization To Improve Drug Delivery For Chitosan-Calcium Phosphate Bone Scaffold Construct B. T. Reves1, J. D. Bumgardner1, J. Cole1, Y. Yang2, W. O. Haggard1; 1University of Memphis, Memphis, TN, 2University of Tennesse Health Science Center, Memphis, TN.
148. Design of a Tissue Engineering System to Influence and Quantify Oxygen Gradients E. F. Bland, K. J. L. Burg; Clemson University, Clemson, SC.
149. Sustained In Situ Delivery of rhBMP-2 by Conjugation to Novel Biodegradable Nanoparticles A. E. Mercado, X. He, E. Jabbari; University of South Carolina, Columbia, SC.
150. An arginine-based polycation/heparin matrix for the controlled delivery of growth factors B. J. Zern, A. Nguyen, Y. Wang; Georgia Institute of Technology, Atlanta, GA.
151. Translational Research in Expansile Devices for Aneurysm Embolization H. Plenk, Jr.1, G. M. Cruise2; 1Medical Univ.of Vienna, Vienna, AUSTRIA, 2MicroVention Terumo Inc., Aliso Viejo, CA.
152. Control of Macromolecular Drugs Delivery Using Polysaccharide Microgels - J. Schmidt1, A. Virdi2, D. Sumner2, H. Kong1; 1University of Illinois, Urbana, IL, 2Rush Medical College, Chicago, IL.
153. Functionalized Biodegradable Triclosan Macromers for Controlled Release Applications R. S. Bezwada; Bezwada Biomedical, LLC, Hillsborough, NJ.
Musculoskeletal Applications
154. Keratin Biomaterials Activate Regenerative Cells and Promote Peripheral Nerve Regeneration at Early and Late Stages in a Mouse Model P. Sierpinski, J. Garrett, J. Ma, D. Klorig, T. Smith, A. Atala, L. Koman, M. Van Dyke; Wake Forest University, Winston-Salem, NC.
155. Synthesis and Characterization of Chondroitin Sulfate Methacrylamide Micelles J. J. Lim, T. M. Hammoudi, J. S. Temenoff; Georgia Institute of Technology and Emory University, Atlanta, GA.
156. Determination of Adhesion Strength of Discrete Nanocrystalline HA Deposition Using Atomic Force Microscopy G. GUPTA1, P. Gubbi2, G. Shekhawat3; 1Biomet, Inc., Warsaw, IN, 2Biomet 3i, Palm Beach Gardens, FL, 3Northwestern University, Evanston, IL.
157. BoneMaster™ HA: Nanocrystalline Hydroxyapatite Coating for Metallic Orthopedic Implants G. GUPTA; Biomet, Inc., Warsaw, IN.
158. Diamond-on-Diamond Hip Simulator Study with Distraction M. G. Naylor1, D. W. Schroeder1, J. K. Taylor2, S. DesPres2, B. J. Pope2; 1Biomet, Inc., Warsaw, IN, 2Dimicron, Orem, UT.
159. Long-Term Bone Remodeling Around Uncemented Proximally Porous Coated Femoral Stems: Comparison to Un-implanted Contralateral Side G. Paleskar, L. C. Jones, J-W. Bae, M. W. Hungerford, D. S. Hungerford, H. S. Khanuja; Johns Hopkins University, Baltimore, MD.
160. Bone Marrow Regeneration following Tibial Marrow Ablation in Rats is Age Dependent M. Fisher, R. Guldberg, Z. Schwartz, B. D. Boyan; Georgia Institute of Technology, Atlanta, GA.
161. Release and Biopotency of Recombinant Human Platelet-Derived Growth Factor-BB Combined with a Collagen Matrix for Rotator Cuff Repair Y. Liu1, C. S. Young1, J. C. Nickols1, V. Kery1, S. Goldman2, M. Richter2, M. R. Wells3, C. E. Hart1; 1BioMimetic Therapeutics, Inc, Franklin, TN, 2Kensey Nash Corporation, Exton, PA, 3Middle Tennessee State University, Murfreesboro, TN.
162. Determining an optimal medial-lateral resection angle for varus patients undergoing a total knee arthroplasty M. Aanstoos1, D. F. Scott2, R. D. Bloebaum3; 1University of Utah, Salt Lake City, UT, 2Spokane Joint Replacement Center, Spokane, WA, 3VA Medical Center SLC, Salt Lake City, UT.
163. Fluid Shear Stress Affects Differentiation of Growth Plate Chondrocytes T. A. Denison, M. Doroudi, Z. Schwartz, B. D. Boyan; Georgia Institute of Technology, Atlanta, GA.
164. Evidence-based rational for the use of a novel biological scaffold in tendon and ligament repairs J. Brunelle, G. Ritter, A. Ray, T. Sander, C. Nataraj; Pegasus Biologics Inc., Irvine, CA.
165. Hydrophilic Soft-tissue Replacements D. N. Ku; SaluMedica, LLC, Atlanta, GA.
Biomaterials for Nanomedicine: From Bench to Bed
166. Development of a Novel Point-of-Care Wound Diagnostic Device using a Pigmented Thin-Film Substrate J. I. Azeke, A. Ferrara, G. Schultz, O. Moloye, A. Maico, C. Batich; University of Florida, Gainesville, FL.
167. Influence of chemical treatement of electrospun naonofibers on protein adsorption and delivery D. S. Katti, R. Vasita; Indian Institute of Technology Kanpur, Kanpur, INDIA.
168. High Resolution Inkjet Printing as a Tool for Creating Tissue Test Systems C. A. Parzel, T. Burg, R. Groff, M. Hill, B. Stripe, T. Boland, K. Burg; Clemson University, Clemson, SC.
169. Withdrawn
170. Parallel Synthesis of Peptidic Dendrimers as Macromolecular Host for Enantioselective catalysis with the PSW1100 J. Schroer; Chemspeed Technologies, NJ.
171. Fabrication of Nano Crystalline Hydroxyapatite-Polymer Composite N. Meenakshisundaram, M. Rajkumar, V. Rajendran; K.S.Rangasamy College of Technology, Tiruchengode Namakkaldt. Tamil Nadu, India.
Cell Interfacing Technologies
172. Agarose Microgels for Protein Delivery within Embryoid Body Microenvironments A. M. Bratt-Leal, R. Carpenedo, T. McDevitt; Georgia Institute of Technology, Atlanta, GA.
173. Nanoscale Patterning of Active Adhesion Proteins S. Coyer, A. García; Georgia Institute of Technology, Atlanta, GA.
174. Enhanced Mesenchymal Stem Cell Response on Biodegradable Poly( -Caprolactone) Nanowires for Applications in Bone Tissue Engineering J. R. Porter, K. C. Popat; Colorado State Univeristy, Ft. Collins, CO.
175. Phthalimide Neovascular Factor 1 (PNF1) Modulates Endothelial MT1-MMP Activity K. A. Wieghaus, E. P. Gianchandani, J. A. Papin, E. A. Botchwey; University of Virginia, Charlottesville, VA.
176. Phospholipase D Induced Differentiation in MG63 Osteoblast-like Cells in Response to Surface Energy Involves Protein Kinase C M. Fang1, M. Wieland2, B. D. Boyan1, Z. Schwartz1; 1Georgia Institute of Technology, Atlanta, GA, 2Institut Straumann AG, Basel, SWITZERLAND.
177. Chitosan improves the in vivo biological response to soy-based biomaterials A. P. Marques1, T. C. Santos1, R. M. P. da Silva1, S. S. Silva1, J. M. Oliveira1, M. van Griensven2, J. F. Mano1, H. Redl2, R. L. Reis1; 13B’s Research Group, Braga, PORTUGAL, 2Ludwig Boltzmann Institute, Vienna, AUSTRIA.
178. Preliminary Comparison of Titanium Mesh and Dacron Cuffs in Subcutaneous and Percutaneous Rabbit Models K. A. Chapman1, K. N. Richmond2, L. L. Kunz3, C. Mayton4, A. D. Janis1; 1DermaPort, Santa Clarita, CA, 2BioDevelopment Associates LLC, Mountlake Terrace, WA, 3BioGenetics Laboratories PS, Whidbey Island, WA, 4Wasatch Histo Consultants, Winnemucca, NV.
179. Withdrawn
180. The role of substrate stiffness on stem cell differentiation into osteogenic cells X. Li1, A. McClary2, N. Zhang3, A. Scott4, G. D. Prestwich5, X. Wen3; 1Department of Bioengingeering, Clemson University, Charleston, SC, 2South Carolina Governor School of Mathematics and Science, Orangeburg, SC, 3Department of Bioengineering, Clemson University, Charleston, SC, 4Glycosan BioSystems, Inc., Salt Lake City, UT, 5Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT.
181. Human Astrocytoma Cells Are Differentially Susceptible to the Cytotoxic Effects of Metal Oxide Nanoparticles J. C. K. Lai; Idaho State University College of Pharmacy, Pocatello, ID.
182. Mechanical and Biochemical Cues for Adipose Stem Cell Differentiation into Heart Valve Interstitial Cells R. S. Stowers, A. Simionescu, D. T. SIMIONESCU; Clemson University, Clemson, SC.
183. Bone marrow stromal cell function on hybrid microparticles A. Bhat, A. C. Jayasuriya; University of Toledo, Toledo, OH.
184. Quantifying Biofilm-Surface Interactions Using Quartz Crystal Microbalance with Dissipation M. A. Poggi1, H. Uddenberg2; 1Q-Sense Inc, Geln Burnie, MD, 2Q-Sense AB, Goteborg, SWEDEN.
185. Differential Effects of Surfactants on DNA and Protein Transport through a Semipermeable Membrane S. W. Leung, J. C. K. Lai, C. K. Daniels, C. S. Bartolin; Idaho State U, Pocatello, ID.
Tissue Engineering Strategies
186. Enrichment of Adipose-Derived Stem Cells J. J. Lazin, C. Erdman, J. Chen, R. Olivares-Navarette, H. R. Moyer, B. D. Boyan, Z. Schwartz; Georgia Institute of Technology, Atlanta, GA.
187. Comparison between Static and Rotational Culture on Chondrocyte/ Silk Fibroin-based Scaffolds Y. Wang1, C. Lee1, A. Motta2, E. Bella2, C. Migliaresi2, Z. Schwartz1, B. Boyan1; 1Department of Biomedical Engineering and Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, 2Department of Materials Engineering and Industrial Technologies, University of Trento, Via Mesiano, ITALY.
188. Development of a Composite Scaffolding System for Vascular Graft Applications S. Lee, J. Liu, S. Oh, S. Soker, A. Atala, J. J. Yoo; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC.
189. Mechano-morphological Properties of Electrospun Micro/Nanofibrous Vascular Scaffold of Protein/Polyglyconate Blends by Carbodiimide X. Zhang, V. Thomas, Y. K. Vohra; University of Alabama at Birmingham; Birmingham, AL.
190. In Vitro Expanded Living Skin Matrices for Reconstructive Procedures M. R. Ladd, S. Lee, A. A. Atala, J. J. Yoo; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC.
191. Scale up and optimization of hybrid microparticles for bone regeneration A. C. Jayasuriya, A. Bhat; University of Toledo, Toledo, OH.
192. Human Vascular Smooth Muscle Cell Calcification on Poly-lactic Acid 2D Films B. Zhu1, S. R. Bailey2, C. M. Agrawal1; 1The University of Texas at San Antonio, San Antonio, TX, 2The University of Texas Health Science Center at San Antonio, San Antonio, TX.
193. Modeling Oxygen Transport in Modular Tissue Engineering L. E. Corstorphine, M. V. Sefton; University of Toronto, Toronto, ON, CANADA.
194. Biocompatibility of PGG-Stabilized Collagen Scaffolds used for Heart Valve Tissue Engineering M. E. Tedder, D. T. Simionescu; Clemson University, Clemson, SC.
195. Cell recruitment strategies for in vivo vascular tissue engineering A. A. Kurane, N. Vyavahare; Clemson University, Clemson, SC.
196. Numerical Modeling and Cell Adhesion of a Tissue Engineered Loop of Henle Device J. L. Charest; Draper Laboratory, Cambridge, MA.
197. Development of an In Vitro Model for Skin Substitutes with Endothelialized Microvasculature W-H. Liang1, V. Janakiraman2, F. Berthiaume2, H. Baskaran1; 1Case Western Reserve University, Cleveland, OH, 2Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital, Boston, MA.
198. Effect of permeability and pore size on mechanical performance of hydroxyapatite scaffolds post in vitro culture T. Guda, M. Appleford, J. Son, S. Oh, J. L. Ong; University of Texas at San Antonio, San Antonio, TX.
199. Concentrated Plasma as a Carrier for Stem Cell Delivery J. E. Woodell-May1, B. Han2, J. Martin1, Z. Welch1, M. Swift1; 1Biomet, Inc., Warsaw, IN, 2University of Southern California, Los Angeles, CA.
200. Characteristics of Heparin-functionalized Porous PLGA Scaffold for Tissue Regeneration J. S. Son1, S. Oh2, K. Park1, D. K. Han1; 1Biomaterials Research Center, Korea Institute of Science and Technology, Seoul, Republic of Korea, 2The University of Texas at San Antonio, San Antonio, TX.
201. Tissue-Engineered Human Embryonic Extracellular Matrix for Therapeutic Device Applications R. S. Kellar, F. Zeigler, E. Pinney, G. Naughton; Histogen, Inc., San Diego, CA.
202. Alterations in metabolic activity of human umbilical vein endothelial cells cultured on gas-plasma treated poly(d,l-lactic) acid scaffolds A. R. Shah1, P. D. Bowman2, J. C. Wenke2, C. M. Agrawal1; 1University of Texas at San Antonio, San Antonio, TX, 2Institute of Surgical Research, San Antonio, TX.
203. A collagen/vascular smooth muscle cells (SMCs) incorporating elastic scaffold for tissue-engineered vascular graft I. Park; Korea Institute of Science and Technology, Seoul, Republic Of Korea.
204. Porous Elastin Scaffolds with Controlled Degradation Rate for Vascular Grafts T-H. Chuang, D. Simionescu; Clemson University, Clemson, SC.
205. Pulsatile Bioreactor for Conditioning Tissue Engineered Heart Valves L. N. Sierad, A. Simionescu, D. T. Simionescu; Clemson University, Clemson, SC.
206. Alginate Microencapsulation Technology for Percutaneous Delivery of Human Adipose Derived Stem Cells (ADSCs) H. R. Moyer1, J. K. Williams2, Z. Schwartz3, B. D. Boyan3; 1Emory University, Atlanta, GA, 2Children’s Healthcare of Atlanta, Atlanta, GA, 3Georgia Institute of Technology, Atlanta, GA.
207. Effect of Degradation Media on Physical Properties of Porous Plga 86/15 Scaffolds H. E. Naguib1, J. Perron2, J. Daka3, A. Chawla3, R. Wilkins3; 1University of Toronto, Toronto, ON, CANADA, 2University of Ottawa, Toronto, ON, CANADA, 3Health Canada, Ottawa, ON, CANADA.
208. Proliferation constant study of the CRL-1888 mouse tumor cell-line for the application of hyperthermia animal model Y. Kim, E. Hwang; Inje University, Kimhae City, REPUBLIC OF KOREA.
Novel Biomaterials
209. Osteoblast Proliferation and Differentiation are Sensitive to Substrate Stiffness S. Hyzy, K. Smith, R. Olivares-Navarrete, K. Gall, Z. Schwartz, B. D. Boyan; Georgia Institute of Technology, Atlanta, GA.
210. Piezoresponse Force Microscopy of Biological Materials and Cells G. L. Thompson, III1, B. Rodriguez2, S. Kalinin2, S. Hohlbauch3, R. Proksch3, A. Vertegel1; 1Clemson University, Clemson, SC, 2Center for Nanophase Materials Science and Materials Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, TN, 3Asylum Research, Santa Barbara, CA.
211. Contraction of 3D Designed Polycaprolactone Scaffolds During Post-Processing J. M. Kemppainen, A. G. Mitsak, K. L. Wolff, S. J. Hollister, C. Flannigan; University of Michigan, Ann Arbor, MI.
212. Fabrication and Function of Three-Dimensional Device Made of Amino-Group-Modified Titanium Dioxide/Polymer NanoComposite Fibers M. Masuda1, M. Okada1, Y. Kogai1, N. Nitta2, A. Kaya2, T. Yamane2, T. Taguchi3, T. Furuzono1; 1Department of Bioengineering, National Cardiovascular Center Research Institute, Suita/city.Osaka, JAPAN, 2National Institute of Advanced Industrial Science and Technology, Tsukuba/city.Ibaraki, JAPAN, 3National Institute for Materials Science, Tsukuba/city.Ibaraki, JAPAN.
213. Withdrawn
214. Toughness and Modulus of Photopolymerizable Acrylate-based Networks are Altered under Physiological Conditions K. Smith; Georgia Institute of Technology, Atlanta, GA.
215. Development of a Multi-functional Red Blood Cell Analog Using Polyelectrolyte Complex Microparticles T. T. Thula; University of Florida, Gainesville, FL.
216. Degradation Behavior of a Resorbable Composite E. M. Perepezko; Biomet Inc., Warsaw, IN.
217. Development of a swine model for the evaluation of novel compounds in the prevention of postoperative adhesions M. E. Cheung1, B. Fenton2, M. Chapman2, M. Kovacik2, D. Noe2, N. Ree2, S. Lopina1; 1The University of Akron, Akron, OH, 2Summa Health Systems, Akron, OH.
218. Neomycin Bbinding to BHVs Prevent Glycosaminoglycan Loss after Storage and In Vitro Cyclic Fatigue D. Raghavan, N. Vyavahare; Clemson University, Clemson, SC.
219. New Biodegradable Elastic Polymers and Scaffold-Sheet Tissue Engineering Strategy J. Yang, J. Dey, P. Thevenot, L. Tang, K. Nguyen; The University of Texas at Arlington, Arlington, TX.
220. A Novel Bioabsorbable Omega-3 Fatty Acid Based Biomaterial J. F. Ferraro, P. Martakos, T. Karwoski; Atrium Medical Corporation, Hudson, NH.
221. Stability of Autologous Clotting Factor Produced at the Point-of-Care H. Enyart, A. Landis, Z. Welch, J. Martin, J. Higgins; Biomet Biologics, Warsaw, IN.
222. Three Dimensional Polymer Scaffolds for High Throughput Cell-Based Assay Systems K. Cheng, W. Kisaalita; University of Georgia, Athens, GA.
223. Characterization of phosphorylcholine-linked methacrylate polymer 1036 (PC1036) X. Xu, E. Rexer, K. Cromack, C. C. Zhou; Abbott Laboratories, Abbott Park, IL.
224. Comparison of Sterilization Methods for Resorbable Polymers E. M. Perepezko; Biomet Inc., Warsaw, IN.
225. Novel Absorbable Polymers from Functionalized Hydroquinone R. S. Bezwada; Bezwada Biomedical, LLC, Hillsborough , NJ.
226. The Study of Collagen-Chitosan Complex Film Containing VCRmicrospheres H. L. Chen, Jr., H. Chen, Jr., Q. Q. Zhang, Sr., L. R. Liu, Sr., P. Yuan, Jr.; Institute of Biomedical Engineering , Chinese Academy of Medical Sciences, Tianjin, CHINA.