Con-current Oral Abstract Presentations Session 4

Cardiovascular Biomaterials 1

171

Design of a Novel Curved Tube Flow-Stretch-Flexure Bioreactor for Mechanistic Studies in Heart Valve Tissue Engineering

S. Ramaswamy, S. Boronyak, D. Schmidt, M. S. Sacks;

Univ. OF PITTSBURGH, PITTSBURGH, PA.

172

In Vivo Assessment of Electrospun Vascular Scaffolds: A Feasibility Study

B. W. Tillman¹, S. K. Yazdani¹, S. Lee¹, R. L. Geary¹, A. Atala¹, J. J. Yoo¹;

¹Wake Forest Inst. for Regenerative Med., Winston-Salem, NC, ¹Wake Forest Univ. Sch. of Med., Winston-Salem, NC.

173

Layer-by-Layer Assembly with Combined Nitric Oxide Generation and Surface Immobilized Heparin -- A Universal Anti-Thrombotic Coating for Biomedical Implants

J. Yang, S. Mirkazemi, M. E. Meyerhoff;

Univ. of Michigan, Ann Arbor, MI.

174

Polyhedral Oligomeric Silsesquioxane (POSS) Suppresses Enzymatic Degradation of Multiblock Polyurethanes Based on Poly(ε-caprolactone): From Biodegradable to Biostable

J. Wu, X. Gu, P. T. Mather;

Syracuse Univ., Syracuse, NY.

175

Microphase Seperation and Biostability of Polydimethylsiloxane-Based Polyurethanes with Varying Hard Segment Content

T. Choi¹, J. Weksler¹, A. Padsalgikar¹, J. Runt¹;

¹The Pennsylvania State Univ., University Park, PA, ¹AorTech Biomaterials, Scoresby, AUSTRALIA.

176

Novel Urethane bond doped polyesters for cardiovascular tissue engineering

Y. Zhang;

Univ. of Texas at Arlington, Arlington, TX.

Computational Modeling

177

Modeling the formation of poly(ethylene glycol) microspheres above the lower critical solution temperature

D. L. Elbert, M. D. Nichols, E. A. Scott;

Washington Univ., St. Louis, MO.

178

Nutrient Consumption Characteristics in Large Flow-through Bioreactors for Tissue Engineering

S. V. Madihally, M. Devarapalli, D. V. Dhane;

Oklahoma State Univ., Stillwater, OK.

179

Modeling Degradation of Bioabsorbable Polymers and Devices

J. Pan;

Univ. of Leicester, Leicester, UNITED KINGDOM.

180

Strain Transduction in Cells Seeded on a Scaffold Exposed to Uni-Axial Stretching: A Three-Dimensional Finite Element Study

A. R. Bonivtch¹, J. T. Mathis¹, M. E. Van Dyke¹;

¹Wake Forest Inst. for Regenerative Med., Winston-Salem, NC, ¹Southwest Res. Inst., San Antonio, TX.

181

Development of a Molecular Mechanics Model for Chloride-Doped Polypyrrole

J. M. Fonner, C. E. Schmidt, P. Ren;

Univ. of Texas, Austin, TX.

182

Simulation of Tissue Compression Indicates Safeguard^™ Device Does Not Occlude Femoral Artery

W. J. Kelly¹, B. Leschinsky¹;

¹Mechanical Solutions, Inc., Whippany, NJ, ¹Datascope Corp., Montvale, NJ.

Dental/Craniofacial Materials

183

Platelet-Rich Plasma (PRP)-enriched Alginate Hydrogel Promotes Angiogenesis of Dental Pulp-Derived Cells

H. H. Lu;

Columbia Univ., New York, NY.

184

Conversion-dependent stress relaxation in dental resins and composites

P. Shah¹, J. Garcia¹, Z. Lakeman¹, A. Plaseied¹, S. Newman¹, J. W. Stansbury¹;

¹Univ. of Colorado, Boulder, CO, ¹Sch. of Dental Med., Univ. of Colorado, Aurora, CO, ¹Univ. of Colorado, Denver, CO.

185

Evaluation of a Microparticle-based Intra-articular Controlled Release System in the Rat Temporomandibular Joint

P. M. Mountziaris¹, P. R. Kramer¹, A. G. Mikos¹;

¹Rice Univ., Houston, TX, ¹Texas A&M Hlth.Sci. Ctr., Baylor Coll. of Dentistry, Dallas, TX.

186

Gingival Osteoblast Co-culture Response to Surface Modified Titanium Implants

A. Satsangi¹, J. Hernandez¹, J. L. Ong¹, S. Oh¹, J. Stmad¹, M. Appleford¹;

¹Univ. of Texas at San Antonio, San Antonio, TX, ¹LASAK Ltd, Prague, CZECH REPUBLIC.

187

Water absorption and wetting properties of dentin adhesives with a urethane-based branched methacrylate

P. Spencer¹, Q. Ye¹, J. Park¹, E. M. Topp¹, X. Yao¹, E. L. Nalvarte¹, Y. Wang¹, B. S. Bohaty¹, A. Misra¹;

¹Univ. of Kansas, Lawrence, KS, ¹Univ. of Missouri-Kansas City, Kansas City, MO.

188

Structural and Polymerization Characteristics of Hydroxyapatite-Impregnated Organophosphate Dental Resin

Q. Ye, J. Park, A. Misra, E. M. Topp, P. Spencer;

Univ. of Kansas, Lawrence, KS.

Medical Devices based on SIBS-type Biomaterials (Symposia)

189

SIBS: Past - Present - Future

J. P. Kennedy;

The Universty of Akron, Akron, PR.

190

Effect of Drug Loading and Polymer Chemistry on the Structure Formation of Drug-Polymer Coatings: Experiments and Simulations

M. K. McDermott, C-S. Kim, D. M. Saylor, D. V. Patwardhan, S. K. Pollack;

FDA, Silver Spring, MD.

191

Alternative to Silicone Rubber: Realizing Promises

G. Lim¹, E. Foreman-Orlowski¹, J. E. Puskas¹, M. Evancho-Chapman¹, S. Valente¹, C. Hart-Spicer¹, S. P. Schmidt¹;

¹Dept. of Polymer Sci., Univ. of Akron, Akron, OH, ¹Div. of Surgicial Res., Akron City Hosp., Akron, OH.

192

SIBS-based Devices for Islet Transplantation

M. Orozco¹, A. Brady¹, N. Kenyon¹, L. Pinchuk¹, C. Ricordi¹, A. Pileggi¹, C. Stabler¹;

¹Innovia LLC, Miami, FL, ¹Univ. of Miami, Miami, FL.

193

Proliferation of Aortic Adventitial Fibroblasts on Three Novel Polyisobutylene (PIB)-based Thermoplastic Elastomers (TPES)

J. E. Puskas¹, L. G. Munoz-Robledo¹, S. E. Porosky¹, M. Evancho-Chapman¹, S. P. Schmidt¹;

¹Dept. of Polymer Sci., Univ. of Akron, Akron, OH, ¹Div. of Surgicial Res., Akron City Hosp., Akron, OH.

Novel Techniques for Processing of Ceramics, Metal and Composite Biomaterials

194

Structural Characterization and Nanomechanical Evaluation of Hydroxyapatite Coatings on Ultrafine Grained Titanium via Low Temperature Thermal Processes

K. L. Calvert;

Purdue Univ., West Lafayette, IN.

195

Mechanical Properties of a Hydoxyapatite-Collagen Composite

R. F. Banglmaier, P. J. VandeVord;

Wayne State Univ., Detroit, MI.

196

Effects of Fuel Ratio on the Biomimitic Properties of Multiphasic Calcium Phosphate Created via Auto-Ignition Combustion Synthesis (AICS)

N. L. Vollmer¹, M. Godek¹, K. King¹, R. Ayers¹;

¹Colorado Sch. of Mines, Golden, CO, ¹Covidien, North Haven, CT, ¹Univ. of Colorado Hlth.Sci. Ctr. Dept. of Orthopedics, Denver, CO.

197

Low Magnetic Susceptibility Zr-Nb Alloys to Prevent Artifacts in MRI

T. Hanawa, N. Nomura, Y. Tanaka, R. Kondo, Y. Tsutsumi, H. Doi;

Tokyo Med. and Dental Univ., Tokyo, JAPAN.

198

Characterization of High Temperature Treated UHMWPE

S. T. Lin¹, D. C. Sun¹, I. Liu¹, C-W. Liao¹, J. Steffens¹, T. Lance¹;

¹Exactech, Gainesville, FL, ¹Taiwan Scientific Corp., Taipei, TAIWAN, ¹Univ. of Florida, Gainesville, FL.

199

In vitro Characteristics of Self Assembled Polycaprolactone Matrices in Aqueous Media

S. V. Madihally, S. Pok, P. Iyer;

Oklahoma State Univ., Stillwater, OK.

Smart (Bio)Polymer Delivery Systems for Biologics

200

Effect of Entrapped Drug on the Micellization Behavior of a Thermosensitive Graft Copolymer

L-Q. Wang, Sr.¹, S. Tan, Sr.¹, H. Jiang, Sr.¹, K. Tu¹, H. Wang, Sr.¹, D. Liu¹;

¹zhejiang Univ., Hangzhou, CHINA, ¹Zhejiang Univ., Hangzhou, CHINA.

201

Resensitizing multidrug resistant cells to doxorubicin through plk1 knockdown using a novel pH-responsive micelle siRNA delivery system

D. S. W. Benoit, S. M. Henry, A. S. Hoffman, P. S. Stayton;

Univ. of Washington, Seattle, WA.

202

The Development of Oral Drug Delivery Systems Using PEGylated Insulin

M. A. Kanzelberger, N. A. Peppas;

Univ. of Texas at Austin, Austin, TX.

203

Formulation Of A Hierarchically Designed Peptide Nucleic Acid Based DNA Delivery Construct

P. G. Millili, U. P. Naik, M. O. Sullivan;

Univ. of Delaware, Newark, DE.

204

Development of Polymeric Carrier Systems with Multiple Burst Release Potential for Treatment of Osteoarthritis

T. Jiang, R. Rosenberger, G. Call, J. Gao, J. Yao;

Zimmer Orthobiologics, Inc., Austin, TX.

205

Effective Intracellular Delivery of an Anti-Cancer Peptide via a RAFT-Synthesized Polymer Conjugate

C. L. Duvall, A. J. Convertine, D. S. W. Benoit, A. S. Hoffman, P. S. Stayton;

Univ. of Washington, Seattle, WA.