Poster Presentations

Adipose Tissue Engineering and Adipose-derived Stem Cells

331

Specific Calcium Phosphate Ceramics Facilitate Cell Proliferation and Adhesion on Ostochondral Allograft

J. A. Szivek, A. S. Ferng, J. L. Howard, C. P. Geffre;

Univ. of Arizona, Tucson, AZ.

332

Injectable, Decellularized Adipose Extracellular Matrix as a Scaffold for Soft Tissue Engineering

D. A. Young, D. P. Hu, K. L. Christman;

Univ. of California, San Diego, La Jolla, CA.

333

The Effect of Mammary Epithelial Cell Conditioned Media on Adipose Cell Differentiation in Two-Dimensional Culture

C. T. Gomillion, K. J. L. Burg;

Clemson Univ., Clemson, SC.

334

Soft Scaffolds for Adipose Tissue Engineering Based on Poly Ethylene Glycol -Gelatin Systems

M. Tanzi, R. Levato, L. Altomare, S. Farè;

Politecnico di Milano, MILANO, ITALY.

Advances in Ophthalmic Biomaterials Technology

335

Bioengineering Eodothelialized Neo-Corneas

J. Choi¹, J. Williams¹, M. Greven², K. Walter³, P. Laber³, S. Soker¹;

¹Wake Forest Univ. Hlth.Sci., Winston-Salem, NC, ²Wake Forest Univ. Sch. of Med., Winston-Salem, NC, ³Dept. of Ophthalmology, Wake Forest Univ. Sch. of Med., Winston-Salem, NC.

336

Feasibility of Drainage to the External Ocular Surface as a New Glaucoma Therapy

L. J. Camras¹, C. B. Camras²;

¹Duke Univ., Durham, NC, ²Univ. of Nebraska Med. Ctr., Omaha, NE.

337

PNIPAAm-Grafted-Collagen as an Injectable, In Situ Gelling Delivery Scaffold for Retinal Cell Therapy

S. D. Fitzpatrick, H. Sheardown;

McMaster Univ., Hamilton, ON, CANADA.

338

Design and Validation of a Bioreactor for Scleral Tissue

P. Ganesan, C. F. Wildsoet;

Univ. of California, Berkeley, Berkeley, CA.

339

Engineering Bruch’s membrane using polyethylene glycol diacrylate hydrogels

D. N. Patel, T. Tezel, A. S. Gobin;

Univ. of Louisville, Louisville, KY.

340

Kinetics and elasticity of in-situ forming silicone or silicone-g-PEG polymers for lens refilling

H. Lee, M-k. Kim, G. Tae, Y. Kim;

Gwangju Inst. of Sci. and Technology, Gwangju, KOREA, REPUBLIC OF.

Applications of Nanomaterials in Medicine

341

Effect of Electrical Stimulation on Staphylococcus Aureus Growth on Anodized Nanotubular Titanium

K. M. Kummer, B. Ercan, E. N. Taylor, T. J. Webster;

Brown Univ., Providence, RI.

342

Biomimetic Hybrid Nanomatrix for Cardiovascular Applications

A. Andukuri¹, M. Kushwaha¹, A. Tambralli¹, J. M. Anderson¹, K. S. Melvin¹, J. Berry², D. R. Dean¹, B. C. Brott¹, H-W. Jun¹;

¹Univ. of Alabama at Birmingham, Birmingham, AL, ²Wake Forest Univ., Winston-Salem, NC.

343

Efficient In-Vivo Tumor Targeting of Chitosan-Conjugated, Pluronic-Based Nano-Carriers

W. Choi¹, J-Y. Kim¹, S-Y. Lee², K. Kim², I. Kwon², Y. Kim¹, G. Tae¹;

¹Gwangju Inst. of Sci. and Technology, Gwangju, KOREA, REPUBLIC OF, ²Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF.

344

MMP-responsive release of DNA from electrospun nanofibrous matrix in diabetic ulcers

H. Kim, H. Yoo, J. Choi, S. Park, H. Jung, Y. Son;

kangwon Natl. Univ., Chuncheon, KOREA, REPUBLIC OF.

345

Control of Cellular Functions by Layer-by-Layer Nanofilms Prepared on Cell Surface

K. Kadowaki, M. Matsusaki, M. Akashi;

Graduate Sch. of Engineering, Osaka Univ., Osaka, JAPAN.

346

Effect of Molecular Structure of PEG on the Biological and Therapeutic Potentials of PEGylated Human Growth Hormone Derivatives

S. Chae, S. Son, S. Jung, K. Lee;

Coll. of pharmacy, SungKyunKwan Univ., Suwon, KOREA, REPUBLIC OF.

347

Chitosan Coated Gold Nanoparticles for Hepatocellular Carcinoma Treatment via Photothermal Therapy

G. Zhang¹, A. M. Gobin²;

¹Univ. of Louisville, Louisville, KY, ²Univ. of Louisville,, Louisville, KY.

348

Synthesis and Applications of Micro- and Nanostructured Hydrogel Composites

H. D. Chirra, J. Z. Hilt;

Univ. of Kentucky, Lexington, KY.

349

Fibrous membrane of nano-hybrid poly-L-lactic acid (PLLA)/silica xerogel for guided bone regeneration

T-S. Jang, E-J. Lee, H-E. Kim;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

350

The Effect of Metallic Nanoparticles on Vascular Smooth Muscle Cells

W. McAllister, L. Wiles, E. Drennon, J. Turbeville, P. Kerscher, C. Kitchens, D. Dean;

Clemson Univ., Clemson, SC.

351

Decreased Infection of Nanomodified Endotracheal Tubes in a Bench Top Airway Model

M. Machado¹, T. J. Webster¹, K. M. Tarquinio²;

¹Brown Univ., Providence, RI, ²Rhode Island Hosp., Providence, RI.

352

Cytocompatible Nanogels for Sustained Drug Delivery across Ocular Biological Barriers

G. Misra¹, H. Imai², D. Daley², T. Gardner², T. Lowe¹;

¹Thomas Jefferson Univ., Philadelphia, PA, ²Penn State Univ. Coll. of Med., Hershey, PA.

353

Polyanhydride nanoparticle adjuvants for development of a single dose anthrax vaccine

Y. Phanse, L. Petersen, A. E. Ramer-Tait, B. H. Bellaire, B. Narasimhan, M. J. Wannemuehler;

Iowa State Univ., Ames, IA.

354

Ivy Nanoparticles for Sunscreen UV Protection and Cosmetic Applications

Q. Li, L. Xia, Z. Zhang, M. Zhang;

Univ. of Tennessee, Knoxville, TN.

355

Incorporation of encapsulated cytokines into tissue scaffold provides stabilization and protection during processing and storage

J. Giri¹, R. S. Tuan², M. T. Cicerone¹;

¹Natl. Inst. of Standards and Technology, Gaithersburg, MD, ²Natl. Inst. of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD.

356

Effect of non-N-containing bisphosphonates on nucleation of Nan needle Hydroxyapatite of calcium phosphate cements in SBF exposure

N. nosoudi¹, S. farhang², s. valizadeh¹, f. moztarzadeh¹, M. Gelinsky³, m. rabiee⁴, s. hesaraki⁵;

¹amirkabir Univ. of technology, tehran, IRAN, ISLAMIC REPUBLIC OF, ²payam noor Univ., tehran, IRAN, ISLAMIC REPUBLIC OF, ³dresden Univ., dresden, GERMANY, ⁴4-Babol Noshirvani Univ. of Technology, tehran, IRAN, ISLAMIC REPUBLIC OF, ⁵Material and energy research Ctr., tehran, IRAN, ISLAMIC REPUBLIC OF.

357

Lithocholic acid-Modifed Exendin-4 Loaded Glycol Chitosan Nanoparticle (HGC) for Efficient Protein Drug Delivery System

S. Son¹, S. Chae¹, K. Kim², I. Kwon², K. Lee¹;

¹Coll. of pharmacy, SungKyunKwan Univ., Suwon, KOREA, REPUBLIC OF, ²Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF.

358

Binding Characterization And Cytotoxicity Analysis Of Cell Surface Display Selected Titanium Binddng Peptides On Titanium Implant Surfaces

H. Yazici¹, B. Wilson¹, E. Oren¹, J. S. Evans², M. Sarikaya¹, C. Tamerler¹;

¹Univ. of Washington,Materials Sci. and Engineering,GEMSEC,Genetically Engineered Materials Sci. and Engineering C, Seattle, WA, ²New York Univ., New York, NY.

359

Oleic acid delivered by nanofibers increases bone matrix formation by differentiated marrow stromal cells

T. T. Ruckh, D. A. Carroll, B. S. Smith, K. C. Popat;

Colorado State Univ., Fort Collins, CO.

360

Extracellular Matrix Mimicking Tubular Scaffolds: Accelerated Achilles Tendon Gap Defect Regeneration

R. James¹, M. Hogan¹, S. Kumbar², C. T. Laurencin², A. Chhabra¹;

¹Univ. of Virginia, Charlottesville, VA, ²The Univ. of Connecticut, Farmington, CT.

361

Nanoparticles for drug delivery to respiratory tract for prophylaxis of free radical-induced damage.

A. Vertegel¹, V. Reukov¹, V. Maximov¹, C. Atkinson², R. Mulligan², R. Schlosser²;

¹Clemson Univ., Clemson, SC, ²Med. Univ. of South Carolina, Charleston, SC.

362

β-Cyclodextrin-based Nanoparticles Containing Quaternary Amine for Drug Delivery to the Retina

L. Wu, J. Zhang, G. P. Misra, T. L. Lowe;

Thomas Jefferson Univ., Philadelphia, PA.

Bio-adhesives in Dental Implants

363

Plasma Treatment of Dentin Surface for Enhanced Adhesive Bonding

A. C. Ritts¹, H. Li¹, Q. Yu¹, J. Claybrooks¹, Y. Wang², X. Yao², C. Xu², L. Hong², M. Chen³;

¹Univ. of Missouri, Columbia, MO, ²Univ. of Missouri-Kansas City, Kansas City, MO, ³Nanova, Columbia, MO.

364

Influence of microsize groove surface on human osteoblasts behavior and initial adhesion evaluated by cytodetacher

S-P. Y. Yang, T-M. Lee, T-S. Lui, M-c. Hsieh;

Natl. Cheng Kung Univ., Taiwan, Tainan, TAIWAN.

Biofilm-Material Interactions

365

Non-Invasive Quantification of Plasmid Dynamics: Biofilm Formation Effect on Plasmid Segregational Loss

H. Ma, J. D. Bryers;

Univ. of Washington, Seattle, WA.

366

Surface Self-Assembled PEG Hydrogel Particles to Control Bacteria-Biomaterial Interactions

Q. Wang, C. Valmikinathan, X. Yu, M. Libera;

Stevens Inst. of Technology, Hoboken, NJ.

367

Antibacterial Function of Novel Peptide Incorporated Titanium Alloys and Feasibility of This Surface Treatment for Orthopaedic Implantations

C. Y. Yeung, L. Li, K. Yeung, R. Kao, D. Yang, K. Luk, K. Cheung;

The Univ. of Hong Kong, Hong Kong, HONG KONG.

368 - Withdrawn

369

Layer-by-Layer Antimicrobial Hydrogel Thin Films

S. Pavlukhina, A. Patimetha, M. Libera, S. Sukhishvili;

Stevens Insttute of Technology, Hoboken, NJ.

370

Biostable, Highly Swellable Polyether-urethane-ureas and Polyether-siloxane-urethane-urea: A Preliminary Report

G. T. Hilas¹, K. J. L. Burg², S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

371 - Withdrawn

372

Comparison of staphylococcal specific and non-specific adhesion to adsorbed fibronectin

J. A. Callihan, J. D. Bryers;

Univ. of Washington, Seattle, WA.

373

Electron-Beam Patterned Surfaces to Control S. aureus and Osteoblastic Cell Adhesion

Y. Wang¹, G. Subbiahdoss², J. Swartjes², H. C. van der Mei², H. J. Busscher², M. Libera¹;

¹Stevens Inst. of Technology, Hoboken, NJ, ²Univ. Med. Ctr. Groningen, Univ. of Groningen, Groningen, NETHERLANDS.

374

Development of Novel Antimicrobial Agents to Prevent Medical Device Related Infections

M. Zhang, J. Bryers;

Univ. of Washington, Seattle, WA.

375

Zinc and Silver Glass Polyalkenoate Cements: An Evaluation of their Antibacterial Nature.

A. Coughlan, M. Towler;

Alfred Univ., Alfred, NY.

376

Novel Dimethacrylates with Quaternary Ammonium Functionalities for Reduced Bacteria Adhesion

N. J. Lin, J. M. Antonucci, D. N. Zeiger, K. Tang, B. O. Fowler, S. Lin-Gibson;

Natl. Inst. of Standards and Technology, Gaithersburg, MD.

Biomaterial Technologies for Treating Segmental Bone Defects: Research Developments and Clinical Applications

377

Effects of Composition and Setting Environment on Mechanical Properties of a Composite Bone Filler

M. E. Brown, Y. Zou, D. A. Puleo;

Univ. of Kentucky, Lexington, KY.

378

Mechanical Properties of Poly(propylene fumarate) Reinforced Brushite Cement: Effects of Cement Composition and Powder to Liquid Ratio

D. L. Alge¹, T-M. G. Chu²;

¹Purdue Univ., West Lafayette, IN, ²Indiana Univ. Sch. of Dentistry, Indianapolis, IN.

379

Evaluation of silicon substituted in situ setting calcium phosphate cements

X. Liu, M. Fulmer;

Synthes Biomaterials, West Chester, PA.

380

Machining of A Novel Bioactive Fixation Device

A. Sparnell, A. El-Ghannam;

The Univ. of North Carolina at Charlotte, Charlotte, NC.

381

Resorbable, bilayer polymer membranes for multi-modal drug release

A. Satsangi, B. Xiao, J. W. Hernandez, J. L. Ong;

Univ. of Texas at San Antonio, San Antonio, TX.

382

Biodegradable and bio-inspired scaffold for bone tissue engineering

A. Akkouch, Sr.;

Laval Univ., québec, QC, CANADA.

383

In vivo assessment of Callos®/OsteoVation® Calcium Phosphate Cement Containing Autologous Bone

S. Jalota, D. C. Delaney, D. N. Yetkinler;

Skeletal Kinetics, Cupertino, CA.

384

Poly(ester urethane urea) PolyHIPEs as High Porosity Bone Grafts

N. A. Sears, R. S. Moglia, H. A. Benhardt, E. M. Cosgriff-Hernandez;

Texas A&M Univ., College Station, TX.

385

CPP-EM-PVA composite as a promising scaffold for the prevention and treatment of aseptic loosening

W. Song¹, C. Wan², D. Markel³, R. Blasier³, W. Ren¹;

¹Wayne State Univ., Detroit, MI, ²Sichuan Univ., Chengdu, CHINA, ³Detroit Med. Ctr./ Providence Hosp. Orthopedic Surgery Dept., Southfield, MI.

386

Quantitative MicroCT Analysis of SCPP-Erythromycin (EM)-PVA Scaffold

A. Esquivel¹, W. Ren², W. Song², R. Blasier³, D. Markel¹;

¹Providence Hosp. and Med. Ctr.s, Southfield, MI, ²Wayne State Univ., Detroit, MI, ³Detroit Med. Ctr., Detroit, MI.

387

Improvement of Interfacial Compatibility in Polyurethane/Tricalcium Phosphate Composite Bone Cements Through Filler Surface Modification

E. M. Prieto, K. Zienkiewicz, D. C. Harris, S. A. Guelcher;

Vanderbilt Univ., Nashville, TN.

388

Bioactive Cements for Spinal Augmentation.

M. R. Towler, A. W. Wren;

Alfred Univ., Alfred, NY.

389

Nanoindentation of microstructural elements in bone cement

J. Gurganus, L. D. T. Topoleski;

Univ. of Maryland Baltimore County, Baltimore, MD.

390

Oxidative Stability of Antioxidant Containing Ultra High Molecular Weight Polyethylene at 80 kGy Sterilization Dose

A. Senyurt, V. Narayan, D. Warner;

DePuy Orthopaedics, Warsaw, IN.

391

A NEW GENERATION OF EASILY CROSSLINKABLE POLYETHYLENE COPOLYMERS

E. Wisse;

DSM Res., Geleen, NETHERLANDS.

Biomaterial-guided Stem Cell Behavior in the Musculoskeletal Realm

392

Copolymer Stiffness Regulates the Differentiation of MG63 Osteoblast-like Cells

K. Smith, S. Hyzy, K. Gall, Z. Schwartz, B. Boyan;

Georgia Inst. of Technology, Atlanta, GA.

393

Mimicking the Stem Cell Microenvironment: The role of mechanical load on the chondrogenesis of human bone derived mesenchymal stem cells in fibrin-polyurethane scaffolds

M. J. Stoddart, Z. Li, D. Eglin, M. Alini;

AO Res. Inst., Davos Platz, SWITZERLAND.

394

Biomaterial Induces Host Stem Cell Recruitment for In Situ Muscle Regeneration

Y. Ju, C. Hwang, A. Atala, J. J. Yoo, S. Lee;

Wake Forest Univ. Hlth.Sci., Winston-Salem, NC.

395

Polymethylmethacrylate Particles Inhibit Human Mesenchymal Stem Cell Osteogenesis

R. Chiu, R. L. Smith, S. B. Goodman;

Stanford Univ. Sch. of Med., Stanford, CA.

396

A Novel Degradable PEG-based Hydrogel to Improve Delivery of Progenitor Cells for Tendon Repair

Y. Qiu, L. Scott, Jr., J. J. Lim, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.

397

Controlling Stem Cell Mechanosensitivity by Nanotopographic Culture

J. Lim¹, J. D. Salvi², H. J. Donahue³;

¹Univ. of Nebraska-Lincoln, Lincoln, NE, ²Cornell Univ., New York, NY, ³Pennsylvania State Univ., Hershey, PA.

398

Substrate Nanotopographic Regulation of Stem Cell Differentiation

J. Lim¹, J. D. Salvi², Y. Zhang³, C. Niyibizi³, H. J. Donahue³;

¹Univ. of Nebraska-Lincoln, Lincoln, NE, ²Cornell Univ., New York, NY, ³Pennsylvania State Univ., Hershey, PA.

399

Delivery of platetet-derived growth factor as a chemotactic factor for mesenchymal stem cells

Y. Xu, M. C. Phipps, S. L. Bellis;

Univ. of Alabama at Birmingham, Birmingham, AL.

400

Variance of Extracel Hydrogel Compositions and the Osteogenic Effects on GFP-reporter Preosteoblasts

Y. Liu, A. J. Goldberg, L. T. Kuhn;

Univ. of Connecticut Hlth.Ctr., Farmington, CT.

401

Effect of Polymer Scaffold Structure on Human Bone Marrow Stromal Cell Differentiation

G. Kumar¹, M. F. Young², C. G. Simon, Jr.¹;

¹NIST, Gaithersburg, MD, ²NIH, Bethesda, MD.

402

Interaction of Mesenchymal Stem Cells with Electrospun Composite Scaffolds to Assess Potential for Bone Regeneration

M. C. Phipps¹, W. Clem¹, A. Schmitt², Y. Vohra¹, S. Bellis¹;

¹Univ. of Alabama at Birmingham, Birmingham, AL, ²Univ. of Montevallo, Montevallo, AL.

403

Mesenchymal Stem Cell Response on Ion Beam Sputter-coated Hydroxyapatite Surfaces

N. A. Riedel, J. Williams, K. C. Popat;

Colorado State Univ., Fort Collins, CO.

404

Magnesium-Yttrium Alloys for Treating Anterior Cruciate Ligament Injuries

H. Liu, D. Perchy, S. Woo;

Univ of Pittsburgh, Pittsburgh, PA.

Biomaterials as Stem Cell Niche

405

Neural Progenitor Cell Stabilization of 3D Fabricated Microvascular Networks

C. A. Williams¹, M. F. Rauch¹, M. Michaud¹, R. Robinson¹, J. Madri¹, E. Lavik²;

¹Yale Univ., New Haven, CT, ²Case Western Reserve Univ., Clevland, OH.

406

Rebuilding complete vascular network at traumatic brain injury lesion site using in situ crosslinkable hydrogel

X. Li, X. Liu, L. Cui, X. Wen, N. Zhang;

Clemson Univ., Charleston, SC.

407

Osteogenic Composites Based on Citric Acid and Calcium Phosphates

E. Chung, G. Ameer;

Northwestern Univ., Evanston, IL.

408

Collagen Biomatrices for Enhanced Endothelial Progenitor Cell Differentiation, Proliferation and Survival

D. Kuraitis, Y. Zhang, B. Vulesevic, D. McKee, M. Ruel, E. J. Suuronen;

Univ. of Ottawa Heart Inst., Ottawa, ON, CANADA.

409

Adhesion to Bioactive Poly(ethylene glycol) (PEG) Hydrogels Promotes Expansion of Hematopoietic Progenitor Cells

M. L. Rowland, J. S. Altus, J. L. West;

Rice Univ., Houston, TX.

410

Microarray study of chondrocyte secreted factors inducing osteogenic differentiation of bone marrow stromal cells

S. Janardhanan¹, J. P. Fisher²;

¹Dept. of Chemical and Biomolecular Engineering, Univ. of Maryland Coll. Park, College Park, MD, ²Fischell Dept. of Bioengineering, Univ. of Maryland Coll. Park, College Park, MD.

411

Regulation of mesenchymal stem cell differentiation by novel stepwise osteogenesis-mimicking matrices

T. Hoshiba, N. Kawazoe, T. Tateishi, G. Chen;

Natl. Inst. for Materials Sci., Tsukuba, JAPAN.

412

Effect of Substrate Stiffness on Differentiation and Electrophysiology of Cardiomyocytes

J. G. Jacot, J. D. Myers, J. J. Petsche;

Rice Univ., Houston, TX.

413

Cytocompatible Cell Immobilization 3D Matrix by Reversible phospholipid polymer hydrogel to manipulate the differentiation for elaborating stem cell niche

T. Konno, K. Ishihara;

The Univ. of Tokyo, Tokyo, JAPAN.

414

Gene Expression Analysis of Osteoblast-related Factors in Human Bone Marrow Cells from Patients with Total Hip Replacement

W. Ren;

Wayne State Univ., Detroit, MI.

415

Novel Biological Scaffolds for 3-D Stem Cell Culture

Q-Q. Qiu, E. Lella, E. Cui, W. Zuo, H. Xu, J. Connor;

LifeCell Corp., Branchburg, NJ.

Biomaterials Education SIG

416

NSF RET Program to Incorporate Bioengineering Education in the 4^th and 5^th Grades

E. Lewis, L. A. Friis;

Univ. of Kansas, Lawrence, KS.

Biomaterials for Cell Manufacturing

417

Surface Engineered Mesenchymal Stem Cells for Systemic Cell Targeting

D. Sarkar, Joel A. Spencer, Rohit Karnik, Charles P. Lin, Jeffrey M. Karp;

Brigham and Women's Hosp., Harvard-MIT HST Div., Cambridge, MA.

418

Bioactive Hydrogel Microspheres as a Versatile Support and Delivery System for Stem Cell-Based Therapies

C. L. Franco, J. West;

Rice Univeristy, Houston, TX.

419

Novel thermosensitive poly_D,L lactic acid 3D structure for cell growth and expansion

A. R. C. Duarte, J. F. Mano, R. L. Reis;

3B´s Res. Group, Dept. of Polymer Eng., Univ. Minho, Caldas da Taipas, Guimarães, PORTUGAL.

420

Open Porous Microscaffolds for Cell Manufacturing and Tissue Engineering by Solid Lipid Templating

K. Ambrosch, S. Junghans, S. Beyer, A. Reinecke, M. Schulz-Siegmund, M. C. Hacker;

Univ. of Leipzig, Leipzig, GERMANY.

Biomaterials for Directed Stem Cell Differentiation

421

Surface Modification of Selective Laser Sintered Nanocomposite Scaffolds and Osteogenic Differentiation of Mesenchymal Stem Cells on the Scaffolds

B. DUAN, M. Wang, Z. Li, W. Lu;

The Univ. of Hong Kong, Hong Kong, HONG KONG.

422

pDNA-containing PLGA/Pluronic F127 porous scaffold for the effective chondrogenic differentiation of mesenchymal stem cells

T. KIm¹, S. Jang¹, S. Oh¹, H. Kim², G. Im², J. Lee¹;

¹Hannam Univ., Daejeon, KOREA, REPUBLIC OF, ²Dongguk Univ. Intl. Hosp., Seoul, KOREA, REPUBLIC OF.

423

The Role of the Growth Factor-Coated Nano-Beads in Chondrocytic Differentiation of Bone Marrow Stromal Cells

H-N. Hao, J. D. Peduzzi, R. A. Teitge;

Wayne State Universtiy, Sch. of Med., Detroit, MI.

424

Carbon nanotube carpets as substrates for programming stem cell differentiation

E. Jabbarzadeh, A. I. Aria, M. Gharib;

California Inst. of Technology, Pasadena, CA.

425

Material-Based Cues that Influence Mesenchymal Stem Cell Differentiation for Use in Cartilage Scaffolds

J. Kadrmas, J. Liu;

Purdue Univ., West Lafayette, IN.

Biomimetic Materials for Tissue Engineering

426

Enzyme triggered RGD-incorporated Tetronic tyramine hyrogels for the controlled myoblast function

I. Jun¹, K. M. Park², K. D. Park², H. Shin¹;

¹Dept. of Bioengineering, Hanyang Univ., Seoul, KOREA, REPUBLIC OF, ²Dept. of Molecular Sci. and Technology, Ajou Univ., Suwon, KOREA, REPUBLIC OF.

427

Hydroxyapatite Mineralization on Porous Silicon Surfaces and in 1-D Gels for Biomimetic Applications

A. Richter¹, J. Dorvee¹, A. Boskey², L. Estroff¹;

¹Cornell Univ., Ithaca, NY, ²Hosp. for Special Surgery, New York, NY.

428

A Simple Template to Align Electrospun Fibers in a User-Defined Manner

A. Karchin, J. E. Sanders;

Univ. of Washington, Seattle, WA.

429

Development of a Novel Silica Sol Vapor Deposition System for use in Interfacial Tissue Constructs

K. L. Snyder, N. J. Hartman, K. A. Wold, R. M. Rajachar;

Michigan Technological Univ., Houghton, MI.

430

Multi-Layered Electrospun Polydioxanone Collagen Blend Matrices

E. YESILALAN, T. BOLLENBACH, V. RONFARD;

ORGANOGENESIS, INC., CANTON, MA.

431

Biomimicry of the Growth of Dental Enamel from Amelogenin and MMP-20 Sols using a Continuous Titration Approach

V. Uskokovic, W. Li, S. Habelitz;

Univ. of California, San Francisco, San Francisco, CA.

432

Osteogenic Potential of BMP2-loaded Nanocomplex/ Hydroxyapatite Layer on Titanium Surface

S. Bae, K. Park, D. Han;

Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF.

433

Effects of Rastering Velocity on Electrospun Polyeurthane Structure and Mechanical Properties

A. D'Amore, N. Amoroso, W. R. Wagner, M. S. Sacks;

Univ. of Pittsburgh, Pittsburgh, PA.

434

Enhanced Material Thromboresistance with Endothelial Progenitor Cells Overexpressing Thrombomodulin

J. D. Stroncek¹, J. H. Lawson², G. A. Truskey¹, W. M. Reichert¹;

¹Duke Univ., Durham, NC, ²Duke Univ. Med. Ctr., Durham, NC.

435

Tricalcium phosphate based Resorbable Ceramics:Influence of MgO and SrO addition on Mechanical Properties and Biocompatibility

S. S. Banerjee, M. S. Tarafder, A. Bandyopadhyay, S. Bose;

Washington State Univ., Pullman, WA.

436

A Novel Perfusion Based Approach to 3D Gradient Generation in poly (ethylene glycol) diacrylate Hydrogels

M. V. Turturro, G. Papavasiliou;

Illinois Inst. of Technology, Chicago, IL.

437

BMP-2 increases cell density in micropores but not bone volumein macropores in biphasic calcium phosphate scaffolds

A. Wagoner Johson¹, S. K. Lan Levengood², S. Polak¹, A. Maki¹, M. B. Wheeler¹, S. Clark-Deener¹;

¹Univ. of Illinois at Urbana-Champaign, Urbana, IL, ²Univ. of Wisconsin, Madison, IL.

438

Reconstruction of Ligament to Bone Interface: The Stratified Complex of Ligament and Calcified Fibrocartilage Incorporating BMP-2 Loaded Heparin-Based Hydrogel

J. Lee¹, W-I. Choi¹, H. Lee¹, V. Guarino², L. Ambrosio², G. Tae¹, Y. Kim¹;

¹Gwangju Inst. of Sci. and Technology, Gwangju, KOREA, REPUBLIC OF, ²Inst. of Composite and BioMed. Materials-Natl. Res. Council, Naples, ITALY.

439

Decoupling PEG Hydrogel Mesh Size and Modulus with the Integration of 4-arm PEG

M. B. Browning, T. S. Wilems, M. Hahn, E. Cosgriff-Hernandez;

Texas A&M Univ., College Station, TX.

440

Characterization and optimization of elastin based peptides for use in tissue engineered vascular grafts

D. Patel, L. Taite;

Georgia Insitute of Technology, Atlanta, GA.

441 - Withdrawn

442

Injectable alginate based hydrogels with adjustable resorbtion rate

J. Melvik, I. E. Skistad;

NovaMatrix/FMC Biopolymer, Billingstad, NORWAY.

443

Alterations in Fibrin Microstructure via Competitive Knob Peptides and the Implications for Cellular Response

S. E. Stabenfeldt, M. J. Gourley, N. M. Aboujamous, A. S. C. Soon, T. H. Barker;

Georgia Inst. of Technology, Atlanta, GA.

444

Tissue Engineering for Palate Regeneration using Nanofiber Array-based Cell Construct

E. Katsanevakis, Y. Qui, V. Beachley, N. Zhang;

Clemson Univ., Charleston, SC.

445

Bio-inspired Nanocomposite Fibrous Scaffolds for Hard Tissue Regenerative Medicine

T. Chae, H. Yang, F. Ko, T. Troczynski;

Univ. of British Columbia, Vancouver, BC, CANADA.

446

A Macrodesigned, Acellular Scaffold Promoting Endogenous Cell Influx and Viability for Cartilage Regeneration

S. Reed;

UCLA, Los Angeles, CA.

447

Control of Calcium Carbonate Morphologies by Genetically Engineered Peptides

C. G. Gresswell¹, M. Sarikaya¹, C. Tamerler², M. Hnilova¹, E. E. Oren¹;

¹Univ. of Washington, Seattle, WA, ²Istanbul Technical Univ., Istanbul, TURKEY.

448

Interaction of Bone Marrow-Derived Macrophages with Highly Aligned Electrospun Fiber Scaffolds for Neural Engineering Applications

H. Wang, E. Hager, S. Wiseman, R. J. Gilbert;

Michigan Technological Univ., Houghton, MI.

449

The Influence of Fibroblast Growth Factor in a Biomimetic Hydrogel System on Endothelial Cell Proliferation

Y. Yuan, C. M. Klinge, A. S. Gobin;

Univ. of Louisville, Louisville, KY.

450

Biomineralization of A Peptide Hydrogel Scaffold Functionalized with Hydroxyapatite-Binding Peptide

M. Gungormus¹, M. Branco², F. Fong¹, C. Tamerler¹, J. P. Schneider², M. Sarikaya¹;

¹Univ. of Washington, Seattle, WA, ²Univ. of Delaware, Newark, DE.

451

The composition of silica-collagen-calcium phosphate nanocomposites manipulates the ratio of bone forming cells to bone resorbing cells in a co-culture

S. Heinemann, C. Heinemann, H. Worch, T. Hanke;

Technische Univ. Dresden, Dresden, GERMANY.

452

Study of Biomimetic Aggrecan Materials for Chondrocytes Culture

C-W. Lan¹, C-X. Yang¹, L-C. Lin², S-M. Kuo¹, S-J. Chang¹;

¹Dept. of BioMed. Engineering, I-Shou Univ., Kaohsiung, TAIWAN, ²Orthopedics Dept., Kaohsiung Vecterans Gen. Hosp., Kaohsiung, Taiwan R.O.C, Kaohsiung, TAIWAN.

453

Impact of mechanical conditioning and elastogenic factors on biomimetic cell-mediated elastic matrix regeneration in 3-D tissue constructs

L. Venkataraman, A. Ramamurthi;

Clemson Univ., Charleston, SC.

454

A Novel Three-Dimensional Cotton Ball-like Electrospun Nanofibrous Scaffold

B. A. Blakeney, A. Tambralli, J. M. Anderson, A. Andukuri, D. R. Dean, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

455

Elastin Mimetic Hybrid Polymers for Vocal Fold Tissue Engineering

S. E. Grieshaber, A. J. E. Farran, K. L. Kiick, X. Jia;

Univ. of Delaware, Newark, DE.

456

High Surface Area Tissue Engineering Scaffolds with Multi-Grooved Fibers

S. Chung, M. Gamcsik, M. W. King;

North Carolina State Univ., Raleigh, NC.

457

Fabrication of Oriented Porous Scaffold for Engineering Myocardial Tissue

Z. Xiong, T. Zhang, L. Jin, R. Zhang, Y. Yan;

Dept. of Mechanical Engineering,Tsinghua Univ., BEIJING, CHINA.

458

Tailoring Properties of Microsphere-Based Poly(lactic-co-glycolic acid) Scaffolds

A. Clark, D. Puleo, T. Milbrandt, Z. Hilt;

Univ. of Kentucky, Lexington, KY.

459

The Use of PEG Hydrogels to Analyze Angiogenic Processes In Vitro

A. Porter, C. Klinge, A. Gobin;

Univ. of Louisville, Louisville, KY.

460

Nanoparticle and Nanofiber-based Sundew (Drosera) Scaffolds for Tissue Engineering

S. Lenaghan, W. He, M. Zhang;

Univ. of Tennessee, Knoxville, TN.

461

Preparation and Characterization of Superlowfouling Electrospun Scaffolds of Zwitterionic Polysulfobetaine Methacrylate for Tissue Engineering Applications

R. Lalani;

The Univ. of akron, akron, OH.

462

Development of novel injectable biodegradable elastomers for in situ tissue regeneration

D. Gyawali, P. Nair, R. Tran, Y. Zhang, N. KC, J. Yang;

Univ. of Texas at Arlington, Arlington, TX.

463

Hydroxyapatite Binding Peptide Genetically Fused to Green Fluorescent Protein for Monitoring Mineraliazation

E. Yuca¹, U. Seker², M. Gungormus², A. Yazgan Karatas¹, M. Sarikaya², C. Tamerler²;

¹Istanbul Technical Univ., Istanbul, TURKEY, ²Univ. of Washington Materials Sci. and Engineering, Seattle, WA.

464

Polymeric Nanowire Templates as Scaffolds for Improved Neuronal Cell Functionality

S. L. Bechara, A. C. Judson, K. C. Popat;

Colorado State Univ., Fort Collins, CO.

465

Artificial Extracellular Matrix Proteins with Enhanced Biological Activity

E. W. Fong, D. A. Tirrell;

Caltech, Pasadena, CA.

466

In Vitro Apatitic Film Formation on the Surface of Poly(methyl methacrylate)

S-M. Choi, J-Y. Han, J-A. Lee, S-Y. Kang, W-K. Lee;

Dankook Univ., Yongin-si, Gyeonggi-do, KOREA, REPUBLIC OF.

467

Production and Evaluation of PCL/HA Biological Scaffold with Unidirectionally Aligned Pore Channels

W-Y. Choi¹, H-E. Kim¹, Y-H. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

468

Specific endothelial cell responses to biomimetic surfaces in fibrin gels

G. Sabra, P. Vermette;

Université de Sherbrooke, Sherbrooke, QC, CANADA.

469

A Novel Cell Permeable Target Specific Cyclic Adenosine Monophosphate Analogue for Bone Tissue Engineering

W. Lo, C. T. Laurencin;

Univ. of Connecticut Hlth.center, Farmington, CT.

470

Preliminary in vitro Investigations of a Cervical Disc Replacement using a Synthetic Hydrogel Contained within Woven Bicomponent Polyester Fabric

J. O. Cooper¹, J. D. Bumgardner¹, D. J. DiAngelo², J. Pafford³, W. O. Haggard¹;

¹Univ. of Memphis, Memphis, TN, ²Univ. of Tenessee Hlth.Sci. Ctr., Memphis, TN, ³Spine Wave, Inc, Shelton, CT.

471

Release Kinetics of FITC-Dextran Particles from Bioerodible Multi-layered Fibrin Matrices: A Study of Peripheral and Local Diffusion

H. S. Duong, B. Wu, B. Tawil;

Univ. of California, Los Angeles, Los Angeles, CA.

472

Structure and Characteristics of Hydroxyapatite/Dexamethasone-loaded PLA Bilayered Scaffold for Bone Regeneration

J. SON¹, G. Teja¹, M. Appleford¹, J. Ong¹, J. Kim², S. Choi², S. Oh¹;

¹Univ. of Texas at San Antonio, San Antonio, TX, ²Chungbuk Natl. Univ., Chungbuk, KOREA, REPUBLIC OF.

473

Effect of Osteopontin-Derived Pepide on Vasculogenic Differentiation of Bone Marrow Stromal Cells

J. MA, E. Jabbari;

Univ. of South Carolina, Columbia, SC.

474

Electro-thermally Polarized hydroxyapatite (HAp) Ceramics: Influence of MgO, SrO, and ZnO Dopants

S. Bodhak, S. Bose, A. Bandyopadhyay;

Washington State Univ., Pullman, WA.

475

In situ forming gelatin-based hydrogels via enzyme-mediated reaction for tissue regeneration and drug delivery

K. Park, Y. Joung, K. Park;

Ajou Univ., Suwon, KOREA, REPUBLIC OF.

476

Endothelial Cell Attachment and Shear Dependent Retention on Biomimetic Polymer Coated Vascular Grafts

L. Dudash¹, F. Kligman², K. Kottke-Marchant², R. Marchant¹;

¹Case Western Reserve Univ., Cleveland, OH, ²Cleveland Clinic, Cleveland, OH.

477

Engineering a Hydrogel System for Dental Pulp Regeneration

E. Katsanevakis, X. Li, X. Liu, N. Zhang;

Clemson Univ., Charleston, SC.

478

Cellular Behavior on Hydrogels with Patterned Elasticity is Influenced by Substrate Mechanics and Ligand Density

S. Nemir¹, H. N. Hayenga², J. L. West¹;

¹Rice Univ., Houston, TX, ²Texas A&M Univ., College Station, TX.

479

Synthesis and folding characteristics of polydepsipeptides

M. M. Nguyen, M. Abdelmelek, K. Masada, D. Campbell, P. Ren, L. Suggs;

Univ. of Texas, Austin, TX.

480

Zinc and Magnesium doped Calcium Phosphate Nanomatrix for Bone Tissue Engineering

W. Paul, C. P. Sharma;

Sree Chithra Tirunal Inst. for Med. Sci. and Technology, Thiruvananthapuram, INDIA.

Cancer Drug Delivery

481

Growth rate of mouse tumor of local hyperthermia treated with paclitaxel coated Duplex Stainless Steel Thermo-rods

Y. Kim¹, H. Choo¹, E. Whang¹, S. Choi²;

¹INJE Univ., Kimhae City, KOREA, REPUBLIC OF, ²Catholic Univ. of Pusan, Busan, KOREA, REPUBLIC OF.

482

Release of Calcein from Liposomes using Low-Frequency Ultrasound

G. A. Husseini¹, W. G. Pitt², J. Hartley², T. Atkinson²;

¹American Univ. of Sharjah, Sharjah, UNITED ARAB EMIRATES, ²Brigham Young Univ., Provo, UT.

483

Conjugation of polyethylene glycol to polyamidoamine dendrimer through bis-aryl hydrazone linkage for enhanced gene delivery

Q. Yuan, W. Yeudall, H. Yang;

Virginia Commonwealth Univ., Richmond, VA.

484

Mineralization of Hyaluronic Acid Nanoparticles and Their Potential as the Robust Carrier of Doxorubicin

S. Han;

Kyung Hee Univ., Youngin, KOREA, REPUBLIC OF.

485

Competing Properties of Mucoadhesive Films that Release Immune Response Modifiers

S. K. Ramineni, D. Puleo, L. Cunningham;

Univ. of Kentucky, Lexington, KY.

486

Physicochemical Characteristics of Hydrotropic Polymer Micelles Bearing Superparamagnetic Iron oxide and Paclitaxel

H. Yoon¹, K. Choi², G. Saravanakumar¹, A. Kim², K. Kim³, J. Park⁴, I. Kwon³, K. Park⁵;

¹Kyung Hee Univ., Gyeonggi-do, KOREA, REPUBLIC OF, ²Kyung Hee Univ., Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ³Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ⁴Kyung Hee Univ., Gwangju Inst. of Sci. and Technology, Gyeonggi-do, Gwangju, KOREA, REPUBLIC OF, ⁵Purdue Univ., West Lafayette, IN.

487

Enhanced antitumor activity using doxorubicin-loaded micelles based on poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]- poly(ethylene oxide) triblock copolymers.

T-H. Kim¹, C. Mount¹, W. Gombotz², S. H. Pun¹;

¹Univ. of Washington, Seattle, WA, ²Omeros Corp., Seattle, WA.

488

Polymeric Micelles for Controlled Delivery of Dexamethasone to Tumors

M. D. Howard¹, M. Jay², Y. Bae¹;

¹Univ. of Kentucky, Lexington, KY, ²Univ. of North Carolina at Chapel Hill, Chapel Hill, NC.

489

Controlled Delivery of Paclitaxel and Heat from Poly(β-amino ester)-Based Magnetic Hydrogel Nanocomposites for the Treatment of Cancer

S. A. Meenach, K. W. Anderson, J. Z. Hilt;

Univ. of Kentucky, Lexington, KY.

490

Polyelectrolyte Negatively Charged Hydrogel for Doxorubicin Delivery

M. Dadsetan, Z. Liu, M. B. Runge, C. Vallejo Giraldo, M. J. Yaszemski;

Mayo Clinic, Rochester, MN.

491

Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery

S. Gong, Sr.;

UW-Milwaukee, Milwaukee, WI.

492

Sustained Delivery Of DHT Via TCPL Delivery System To Develop A BPH Model In Rats

H. A. Benghuzzi, M. A. Tucci, M. C. Pollan;

Univ. of Mississippi Med. Ctr., Jackson, MS.

493

Development and evaluation of a chitosan based injectable gel for brain cancer treatment

S. Kim¹, Y. Yang¹, S. K. Nishimoto², J. D. Bumgardner³, W. O. Haggard³, M. W. Gaber⁴;

¹Univ. of Texas Hlth.Sci. Ctr. at Houston, Houston, TX, ²Univ. of Tennessee Hlth.Sci. Ctr., Memphis, TN, ³Univ. of Memphis, Memphis, TN, ⁴Baylor Coll. of Med., Houston, TX.

Cardiovascular Biomaterials SIG

494

Suture Properties of Swellable, Absorbable Monofilaments

M. S. Taylor¹, D. R. Ingram¹, B. P. Baum¹, D. E. Linden¹, K. J. L. Burg², S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

495

Cathepsins are upregulated in vascular calcification

C. Cheluvaraju, L. Simpson;

Clemson Univ., Clemson, SC.

Cardiovascular Controlled Drug Release

496

The Impact of Sex-Based Differences in Atherosclerotic Plaque on the Response to Drug Eluting Stent (DES) Implantation

J. Guo, D. M. Saylor, D. V. Patwardhan;

Food and Drug Admin., Silver spring, MD.

497

Investigations into the Morphology of the XIENCE V^® Drug Eluting Stent Coating

G. Abraham¹, D. Valdemoro¹, F-W. Tang², S. Pacetti¹;

¹Abbott Vascular, Santa Clara, CA, ²Abbott Vascular, Temecula, CA.

498

Factorial Analysis of Factors Governing Silver Release from a Hydrophilic Coating

J. L. Simon, E. Pervin, D. Pervin, M. Farrell;

Biocoat, Inc., Horsham, PA.

499

Nitric Oxide Releasing Coatings for Medical Devices

R. S. Bezwada;

Bezwada BioMed., LLC, Hillsborough, NJ.

500

Effects of temperature and cleaning on the surface characteristics of cardiovascular stainless steel stents

J. R. Hull, D. G. Castner;

Univ. of Washington, Seattle, WA.

Cardiovascular Material Development and Biointeractions

501

In Situ Gelling Polymer System for Vascular Embolization: Effect of Radio-opaque Agents on Gelation

C. Riley¹, R. McLemore¹, M. C. Preul², B. L. Vernon¹;

¹Arizona State Univ., Tempe, AZ, ²Barrow Neurological Inst., Phoenix, AZ.

502

Biostability of a New Cardiovascular Material

J. Tan;

St. Jude Med., CRM Div., Sylmar, CA.

503

From Non-Absorbable to Absorbable Polymers

R. S. Bezwada;

Bezwada BioMed., LLC, Hillsborough, NJ.

504

Regulation of Material Endothelialization via Polyurethane-Hyaluronic Acid Copolymers

A. Ruiz, K. S. Masters;

Univ. of Wisconsin Madison, Madison, WI.

505

Muscle Cells Align in 3D when Seeded in Channels Patterned into Porous Hydrogels

S. M. LaNasa, S. J. Bryant;

Univ. of Colorado at Boulder, Boulder, CO.

506

Nonfouling Polyurethane Coatings on Cardiovascular Stents to Improve Blood Compatibility

T. A. Horbett, D. Responte, M. Zhang, F. Simonovsky, B. Ratner;

Univ. of Washington, Seattle, WA.

507

Catalytic Nitric Oxide Generation via Layer-by-Layer Assembly on Metal Surfaces

J. Yang¹, W. Cai²;

¹The Univ. of Michigan, Ann Arbor, MI, ²Dept. of Chemistry, Ann Arbor, MI.

508

Functionalized Poly(ethylene glycol) Dimethacrylate Hydrogels with Engineered Surface Topography to Promote Re-Endothelialization of Small Diameter Vascular Grafts

C. M. Magin, A. B. Brennan;

Univ. of Florida, Gainesville, FL.

509

A High Throughput Assay for Optimization of Endothelialization of Mechanical Heart Valve Prostheses

S. M. Tucker, J. Butcher, A. García;

Cornell Univ., Ithaca, NY.

510

Nonfouling Polycarboxybetaine-Grafted Surfaces by Nitroxide Mediated Free Radical Polymerization

S. Abraham, L. D. Unsworth;

Univ. of Alberta, Edmonton, AB, CANADA.

511

Immobilization of corn trypsin inhibitor for inhibition of the contact factor pathways on blood-contacting materials

S. Alibeik, S. Zhu, J. Yau, J. Weitz, J. Brash;

McMaster Univ., Hamilton, ON, CANADA.

512

Shear-Dependent endothelial cell attachment to polymeric biomaterials

X. Wang, D. Heath;

the Ohio State Univ., Columbus, OH.

513

Method for Electrostatically Coating a Medical Device

V. Davé;

Cordis Corp., Warren, NJ.

514

Targeting and differentiating endothelial progenitor cells via surface engineering

R. A. Hoshi, G. A. Ameer;

Northwestern Univ., Evanston, IL.

515

Tailoring the interface of methacrylic terpolymer biomaterials for endothelialization

D. E. Heath, S. L. Cooper;

The Ohio State Univ., Columbus, OH.

516

Influence of Polyethylene Oxide Spacer on Anticoagulant Properties of Immobilized Antithrombin-Heparin Complex

K. N. Sask, L. R. Berry, A. K. C. Chan, J. L. Brash;

McMaster Univ., Hamilton, ON, CANADA.

517

In vivo evaluation of thromboresistance on PLLA/phospolipid polymer blend

H. Kim¹, K. Ishihara¹, M. Takai¹, T. Konno¹, J-S. Seo²;

¹Univ. of Tokyo, Tokyo, JAPAN, ²Seoul Natl. Univ. Coll. of Med., Seoul, KOREA, REPUBLIC OF.

518

Creating Elastogenic Electrospun Scaffolds for Cell-mediated Elastic Matrix Assembly by Vascular Cells

C. A. Bashur, A. Ramamurthi;

Clemson Univ., Clemson, SC.

519

Peptide self-assembly and its effect on hydrogel properties and platelet activation

A. Saini, L. Unsworth;

Univ. of Alberta, Edmonton, AB, CANADA.

Cell and Tissue Derived Biological Materials

520

Acellular Embryonic Stem Cell-Derived Matrices for Vascular Regeneration

A. V. Ngangan, J. C. Waring, N. A. Joe, T. C. McDevitt;

Georgia Inst. of Technology, Atlanta, GA.

521

Surface Characterization by SIMS and SEM of Decellularized Porcine Extracellular Matrix Scaffolds

C. A. Barnes¹, B. N. Brown², D. G. Castner¹, B. D. Ratner¹, S. F. Badylak²;

¹Univ. of Washington, Seattle, WA, ²Univ. of Pittsburgh, Pittsburgh, PA.

522

A Rapid Decellularization Technique for the Recellularization of Renal Organ Tissue

G. Orlando, S-H. Mirmalek-Sani, D. C. Sullivan, P. Baptista, T. AbouShwareb, J. Yoo, A. Atala, S. Soker;

Wake Forest Inst. for Regenerative Med., Winston-Salem, NC.

523

Identification of novel Fibronectin strain-specific binding peptides

L. Cao, M. Zeller;

Georgia Inst. of Technology, Atlanta, GA.

524

Cartilage Regeneration in an Immunocompromised Rat Critical-Size Xiphoid Cartilage Defect Model

Y. Wang¹, L. Xie¹, H. R. Moyer², A. Nizkorodov¹, S. Hyzy¹, Y. Huang³, K. Truncale³, R. E. Guldberg¹, Z. Schwartz¹, B. D. Boyan¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Emory Univ. Med. Sch., Atlanta, GA, ³Musculoskeletal Transplant Fndn., Edison, NJ.

525

Amelogenin Peptide (Fraction C) Induces Osteogenesis and Cementogenesis in hMSCs

R. Olivares-Navarrete¹, K. Vesper¹, M. Dard², C. Mauth², R. Ranevski², Z. Schwartz¹, B. D. Boyan¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Inst. Straumann, Basel, SWITZERLAND.

526

Schwann Cell Gene Expression Profiles After Injection into Decellularized Cold-Preserved Nerve Allografts

N. J. Jesuraj, K. B. Santosa, A. M. Moore, R. Kasukurthi, E. R. Flagg, D. Hunter, G. Borschel, P. J. Johnson, S. E. MacKinnon, S. E. Sakiyama-Elbert;

Washington Univ. in St.Louis, St. louis, MO.

527

Bioscaffolds for Meniscus Transplantation: An In Vivo Sheep Study

J. A. Steen;

Wake Forest Univ., Winston Salem, NC.

528

Terminal Sterilization of Biological Tissue Matrix Using Supercritical CO₂

Q-Q. Qiu, J. Pomerleau, J. Connor;

LifeCell Corp., Branchburg, NJ.

529

In Vitro Expanded Living Skin for Burn Injuries

M. Ladd, V. Romero, S. Lee, J. Bae, H-W. Kang, A. Atala, J. J. Yoo;

Wake Forest Univ. Hlth.Sci., Winston-Salem, NC.

530

Cell Derived Biomaterials for Biomedical Applications

J. C. Wolchok, P. A. Tresco;

Univeristy of Utah, Salt Lake City, UT.

531

Nanochemically oriented astrocytes direct adjacent nerve cell outgrowth

F. Meng, V. Hlady, P. A. Tresco;

Univ. of Utah, Salt Lake City, UT.

532

Microenvironment Changes in the Stem Cell Niche Influence the Differentiation Pathway to Bone

H. A. Coan;

Wake Forest Inst. For Regenerative Med., Winston Salem, NC.

533

Design and Characterization of a Decellularized Pericardial Matrix Gel for Cardiac Tissue Engineering

S. B. Seif-Naraghi, M. A. Salvatore, P. J. Schup-Magoffin, D. P. Hu, K. L. Christman;

UC San Diego, La Jolla, CA.

534

In vivo Evaluation of an Autologous graft and two Acellular Human Dermal Matrices

J. A. Faleris, R. M. C. Hernandez;

RTI Biologics, Alachua, FL.

535

Acellularized Scaffold for Osteogenic Differentiation of Rabbit Bone Marrow Stromal Cells

K. Park¹, Y-J. Hong², I. Kim², D. Han¹;

¹Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ²Coll. of Life Sci. and Biotechnology, Korea Univ., Seoul, KOREA, REPUBLIC OF.

536

Angiogenesis in Hyaluronan Treated Bone Repair

A. L. Raines¹, M. Sunwoo², K. Thacker³, R. E. Guldberg¹, B. D. Boyan¹, Z. Schwartz¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Musculoskeletal Transplant Fndn., Edison, NJ, ³Lifecore BioMed., LLC, Chaska, MN.

537

Bioengineering of red blood cells by the Layer-by-Layer self-assembly technique

S. Mansouri¹, Y. Merhi², F. M. Winnik³, M. Tabrizian¹;

¹McGill Univ., Montreal, QC, CANADA, ²Montreal Heart Inst., Montreal, QC, CANADA, ³Univ. de Montreal, Montreal, QC, CANADA.

538

Study of the Stem Cells from Goat Bone Marrow Stroma Placed on a Biological Graft for Artificial Ligament

Q. Liu¹, Y. Wang¹, X. Peng¹, Y. Lin², B. Xu², X. Guo², G. Xu², B. Gao³;

¹Jinan Univ., Guangzhou, CHINA, ²Grandhope Biotech Co., Ltd, Guangzhou, CHINA, ³Clemson Univ., Clemson, SC.

539

Decellularized Skeletal Muscles: Model Systems to Study Changes in Extracellular Matrix and their Effect on Stem Cell Differentiation

A. Gillies, L. Smith, Y. Hwang, R. L. Lieber, S. Varghese;

Univ. of California San Diego, La Jolla, CA.

Cell Function in 2D vs 3D Culture

540

Contrasting effects of 2D vs. 3D hydrogel microenvironments on the behavior of glioblastoma multiformes

S. S. Rao, J. DeJesus, J. Larison, A. Sarkar, J. O. Winter;

The Ohio State Univ., Columbus, OH.

541

Cell Proliferation and Cell Localization Following In Situ Immobilization in a 3D Alginate Foam Matrix

T. Andersen, H. Heier-Baardson, J. Melvik, M. Dornish;

NovaMatrix/FMC Helathcare Ventures, Sandvika, NORWAY.

542

Encapsulation and Survival of a Chondrocytic Cell Line within a Polysaccharide Gum

A. C. Mendes, E. T. Baran, R. C. Pereira, H. S. Azevedo, R. L. Reis;

3B´s Res. Group,Dept. of Polymer Engineering, Guimarães, PORTUGAL.

543

Material-Directed Human Bone Marrow Stromal Cell Differentiation in 2D and 3D Hydrogel Cultures

K. Chatterjee¹, N. M. Moore¹, S. Lin-Gibson¹, M. F. Young², C. G. Simon, Jr.¹;

¹Natl. Inst. of Standards and Technology, Gaithersburg, MD, ²NIH, Bethesda, MD.

544

Collagen Covalently Crosslinked to Micropatterned Agarose Scaffolds for Hepatocyte Culture

A. Y. Au¹, J. M. Hasenwinkel², C. G. Frondoza¹;

¹Nutramax Lab., Inc., Edgewood, MD, ²Syracuse Univ., Syracuse, NY.

545

High Fidelity Photopatterning of Three-Dimensional OPF Hydrogels for Co-Culture Applications

N. C. Bloodworth, T. M. Hammoudi, H. Lu, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.

546

Direct Cell Writing: Process, Viability and Function

J. Snyder¹, R. Chang¹, C. Culbertson², K. Emami³, H. Wu³, W. Sun¹;

¹Drexel Univ., Philadelphia, PA, ²Kansas State Univ., Manhattan, KS, ³NASA JSC, Houston, TX.

547

Novel Modular Plasticware for Three-Dimensional (3-D) Cell Culture

D. Orr, M. Gevaert, R. Drumm;

KIYATEC, Pendleton, SC.

548

Effects of a three-dimensional polystyrene environment on HepG2 liver cells

D. Roy¹, M. K. Bergenstock², Q. Liu², W. Sun¹;

¹Drexel Univ., Philadelphia, PA, ²3D Biotek, LLC, North Brunswick, NJ.

Cell/Organ Therapies SIG

549

A Novel Biomaterial for the Targeted Removal of Advanced Glycation End Products from Blood

K. A. Lapidos¹, E. Zhang¹, S. M. Sprague², G. A. Ameer¹;

¹Northwestern Univ., Evanston, IL, ²NorthShore Univ. Hlth.System, Evanston, IL.

Chemoselective Chemistry for Biomaterials

550

Self-Assembled Synthetic ECMs Displaying Functional Protein Domains

Y. F. Tian, J. Modica, S. Skarpathiotis, M. Mrksich, J. Collier;

Univ. of Chicago, Chicago, IL.

551

Site-directed Conjugation of Bioactive Molecules to Poly(lactic-co-glycolic) Acid Nanoparticles

E. B. P. Jabart¹, B. Helms², L. Sohn¹, I. Conboy¹;

¹UC-Berkeley/UCSF, Berkeley, CA, ²Lawrence Berkeley Natl. Lab, Berkeley, CA.

Collagen:  How the Source and Process Affect the Product

552

Radioprotection of Tendon Allografts and Bioburden Inactivation using Ebeam Radiation

A. Seto, C. J. Gatt, Jr., M. G. Dunn;

UMDNJ-Robert Wood Johnson Med. Sch., New Brunswick, NJ.

553

Collagen scaffold porosity effects its mechanical, biodegradation and inflammation properties

V. Zaporojan, Sr., R. Zhukauskas, E. Shields, P. Bursac;

RTI Biologics, Alachua, FL.

Controlled Release and Presentation Systems for Regulating Cell Behavior

554

Synthesis and Characterization of a Charge-Reversal Photo-Active Amphiphile

C. M. LaManna, J. H. Feng, M. W. Grinstaff;

Boston Univ., Boston, MA.

555

Drug Deliverable, Self-assembled Nanotubes for Bone Tissue Engineering

S. Song¹, Y. Chen¹, T. J. Webster¹, H. Fenniri²;

¹Brown Univ., Providence, RI, ²Univ. of Alberta, Edmonton, AB, CANADA.

556

Runx2 immobilization on poly (epsi-caprolactone) enhances osteoblast differentiation of bone marrow stromal cells in vitro

Y. Zhang, X. Deng, E. Scheller, J. Lahann, R. Franceschi, P. Krebsbach;

Univ. of Michigan, Ann Arbor, MI.

557

Controlled Multi-Agent Delivery of Small Molecule Therapeutics for Applications in Medicine

A. Shukla, R. C. Smith, P. T. Hammond;

Massachusetts Inst. of Technology, Cambridge, MA.

558

Calcium Sulfate/Hydrogel Space-Making Composites for Bone Augmentation

B. R. Orellana, A. M. Hawkins, D. A. Puleo, J. Z. Hilt, M. V. Thomas;

Univ. of Kentucky, Lexington, KY.

559

Bone Tissue Engineering using BMP-2, IFN-gamma, and IL-4 loaded in a Microporous Fibrin Scaffold

J. Cheng, T. Osathanon, O. Horst, E. M. Leaf, M. J. Somerman, C. M. Giachelli;

Univ. of Washington, Seattle, WA.

560

Modulating Phosphate Metabolism for Periodontal Regeneration.

K. J. Nagatomo¹, B. L. Foster¹, T. Osathanon¹, E. Y. Chu¹, K. A. Tompkins¹, H. Fong¹, D. Matsa-Dunn¹, C. Guenther², D. M. Kingsley², R. Rutherford¹, C. M. Giachelli¹, M. J. Somerman¹;

¹Univ. of Washington, Seattle, WA, ²Stanford Univ., La Jolla, CA.

561

The Effect of Ion Content and pH on Plasmid DNA Delivery from Dissolving Mineral Coatings

S. Choi, W. L. Murphy;

Univ. of Wisconsin, Madison, WI.

562

Migration of Stromal Cells in Response to Sustained Release of Stromal Derived Factor-1α

X. He, E. Jabbari;

Univ. of South Carolina, Columbia, SC.

563

Controlled release of insulin-like growth factor-1 from hydrogels improves integration with cartilage

K. L. Spiller¹, Y. Liu², G. Zhou², W. Liu², Y. Cao², A. M. Lowman³;

¹Kara Spiller, Philadelphia, PA, ²Shanghai Key Tissue Engineering Ctr., Shanghai, CHINA, ³Drexel Univ., Philadelphia, PA.

564

Tissue Engineering of Growth Plate using IGF-I Releasing PLGA Scaffolds

S. C. Sundararaj, R. D. Cieply, T. A. Milbrandt, D. A. Puleo;

Univ. of Kentucky, Lexington, KY.

565

Development of Amphiphilic Calcium Alginate Nanoparticles for Controlled Gene Delivery

R. A. Oldinski, J. D. Bryers;

Univ. of Washington, Seattle, WA.

566

Signaling Molecules to Recruit Endogenous Stem Cells for an Engineered Cartilage Healing Response

W. S. Vanden Berg-Foels¹, C. Hicks², X. Wen¹;

¹Med. Univ.of South Carolina, Charleston, SC, ²Cornell Univ., Ithaca, NY.

567

A Micro/Nano Particle Protein Delivery System for Axon Regeneration in Spinal Tissue

J. Coleman, A. Lowman, J. Houle;

Drexel Univ., Conshohocken, PA.

568

Hollow Hydroxyapatite Microspheres for Controlled Delivery of Proteins

H. Fu, M. Rahaman, D. Day;

Missouri Univ. of Sci. and Technology, Rolla, MO.

569

Liquid Injectable Polymers Based On Modified Caprolactone As Potential Drug Delivery Vehicles

I. O. Babasola;

Queens Univ., Kingston, ON, CANADA.

570

Characterization of Bovine Type I Collagen Matrix Combined with Recombinant Human Platelet-Derived Growth Factor-BB (rhPDGF-BB) for Rotator Cuff Repair

Y. Liu, V. Kery, C. Roden, V. Shah, J. Ratliff, A. Thompson, C. Young, H. Kestler, S. E. Lynch, D. J. Aguiar;

BioMimetic Therapeutics, Inc, Franklin, TN.

571

A device based on aerogel silica: physicochemical characterization and antimicrobial test

M. E. Cortes, E. M. G. Raso, N. Mohallen, R. D. Sinisterra;

UFMG, Belo Horizonte, BRAZIL.

Craniofacial Tissue Regeneration

572

Gelatin microparticle-incorporating poly(methyl methacrylate) constructs for craniofacial tissue engineering

M. Shi¹, J. D. Kretlow¹, S. Young², M. E. Wong², F. K. Kasper¹, A. G. Mikos¹;

¹Rice Univ., Houston, TX, ²Univ. of Texas Hlth.Sci. Ctr. at Houston, Houston, TX.

573

Delivery of siRNA using cationic star polymers to suppress Runt Related Transcription Factor 2 and Osterix in vitro

B. Bober, J. Leung, E. Shyr, A. Srinivasan, H. Cho, K. Krzysztof Matyjaszewski, J. Hollinger;

Carnegie Mellon Univ., Pittsburgh, PA.

574

Mechanical, Chemical, and In Vivo Characterization of Biphasic HA/βTCP 3-D Printed Scaffolds for Custom Bone Repair Applications

L. Witek¹, A. Murriky¹, E. Clark¹, M. Pines¹, J. Smay², N. Silva¹, J. Ricci¹;

¹NYU Coll. of Dentistry, New York, NY, ²Oklahoma State Univ., Stillwater, OK.

575

Potential of Poly(E-caprolactone fumarate) as a Bone Tissue Engineering Scaffold

A. Sharma¹, J. Kim¹, M. B. Runge², P. Alvarez-Urena¹, M. Dadsetan², M. J. Yaszemski², J. O. Hollinger¹;

¹Carnegie Mellon Univ., Pittsburgh, PA, ²Mayo Clinic, Rochester, MN.

576

In vitro Evaluation of Mesh-reinforced Absorbable Self-setting Composite Adhesive Bone Cement

K. D. Gray, Jr., S. J. Peniston, R. T. Pace, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

577

A Comparison of Calcium Sulfate Polymer Composites for the Reconstruction of Bone

P. Lee¹, N. Tovar¹, M. Sachin², H. Alexander², M. Pines¹, J. Ricci¹;

¹NYU Coll. of Dentistry, New York, NY, ²Orthogen, LLC, Springfield, NJ.

578

Effect of basic fibroblast growth factor-loaded biomineral/agarose composite gels on bone regeneration

N. Mizuta;

Graduate Sch. of Dentistry, Osaka Univ., Suita, Osaka, JAPAN.

Dental Materials

579

In situ Reactive Electrospinning of PLA-Monetite Nanocomposite Scaffolds for Dental Tissue Engineering

A. H. Ahmed, S. B. Bhaduri;

Univ. of Toledo, Toledo, OH.

580

An Investigation on In Vivo Degradation of Polydioxanone Films in a Rat Model

M. Deng, T. Poandl, M. Mooney, K. Hristov, S. Karoly;

Ethicon, Inc., a Johnson & Johnson Company, Somerville, NJ.

581

Microstructure Development and In vitro dissolution behavior of SiO2-MgO-Al2O3-K2O-B2O3-F glass-ceramics

B. Basu, S. Roy;

Indian Inst. of Technology Kanpur, Kanpur, INDIA.

582

Peri-implant and Periosteal Responses of Titanium and Zirconia Implants in a Rabbit Model

D. Shin¹, S. B. Blanchard¹, M. Ito², T-M. G. Chu¹;

¹Indiana Univ. Sch. of Dentistry, Indianapolis, IN, ²Matsumoto Dental Univ., Nagano, JAPAN.

583

Deactivation of Oral Bacteria Using an Atmospheric Plasma Brush

A. C. Ritts¹, B. Yang¹, J. Chen², Y. Kim¹, H. Li¹, L. Hong³, Y. Wang³, M. Chen⁴;

¹Univ. of Missouri, Columbia, MO, ²Xi’an Jiao Tong Univ., Xi’an, CHINA, ³Univ. of Missouri-Kansas City, Kansas City, MO, ⁴Nanova, Columbia, MO.

Drug Delivery SIG

584

Modulating Notch Signaling to Enhance Neovascularization and Reperfusion in Diabetic Mice

L. Cao¹, P. Arany¹, J. Kim¹, J. Rivera-Feliciano¹, Y-S. Wang¹, Z. He², C. Rask-Madsen², G. L. King², D. J. Mooney¹;

¹Harvard Univ., Sch. of Engineering and Applied Sci., Cambridge, MA, ²Joslin Diabetes Ctr., Harvard Med. Sch., Boston, MA.

585

Thermoreversible Copolymers with Enzyme-Dependent Lower Critical Solution Temperatures

D. J. Overstreet, H. D. Dhruv, B. L. Vernon;

Arizona State Univ., Tempe, AZ.

586

Study of Doxycycline Release Profiles from Different In situ-forming Polymeric Implants

J. M. Olbrich¹, S. D. Nagatomi¹, J. T. Corbett¹, K. A. Nichter¹, K. J. L. Burg², S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

587

Antibiotic-loaded chitosan sponges prevent biofilm formation by MRSA in an established mouse catheter model

S. P. N. Noel¹, K. E. Beenken², M. S. Smeltzer², H. S. Courtney³, J. D. Bumgardner¹, W. O. Haggard¹;

¹Univ. of Memphis, Memphis, TN, ²Univ. of Arkansas for Med. Sci., Little Rock, AR, ³Univ. of Tennessee, Memphis, TN.

588

Development of Gentamicin Containing Bioactive Macroporous Injectable Calcium Phosphate Cement

A. J. McNally, K. Sly, S. Lin;

Exactech Inc., Gainesville, FL.

589

Biostable Non-hormonal Contraceptive Antifungal Intravaginal Ringed-mesh: A Preliminary Study

G. T. Hilas, S. D. Nagatomi, K. A. Nichter, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

590

Effect of Drug Physicochemical Properties on Release Profiles from an Absorbable In situ-forming Implant

J. M. Olbrich¹, D. R. Ingram¹, S. D. Nagatomi¹, J. T. Corbett¹, K. J. L. Burg², S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

Emerging Frontiers in Design and Characterization of Bio-inspired Nanoscale Research & Materials

591

Protein Nanopatterning on a Highly-Oriented Lamellar Surface

M. Omichi¹, M. Matsusaki¹, K. Kadowaki¹, B. H. Kim², S. O. Kim², I. Maruyama³, M. Akashi¹;

¹Osaka Univ., Suita, JAPAN, ²KAIST, Daejeon, KOREA, REPUBLIC OF, ³Kagoshima Univ., Sakuragaoka, JAPAN.

592

Atomic Force Microscopic Analysis of Sundew (Drosera) Adhesive for Biomedical Applications

S. Lenaghan, L. Xia, W. R. Henson, M. Zhang;

Univ. of Tennessee, Knoxville, TN.

593

Electric Characterization of Liquid Crystal Nanocolloids

S. Wu¹, J. Zhou², S. Tsoi², C. Spillmann², J. Naciri², B. Ratna²;

¹Agilent Technologies, Inc, Chandler, AZ, ²Naval Res. Lab., Washington DC, DC.

594

Development of new Reducible Cationic Gemini Surfactant - SS14 - Containing Liposomes for Gene Delivery

G. Candiani¹, D. Pezzoli¹, L. Ciani², A. Cigada¹, R. Chiesa¹, S. Ristori²;

¹Politecnico di Milano, Milan, ITALY, ²Università di Firenze, Florence, ITALY.

595

Mussel-Inspired Surface Functionalization of Graphene Oxide

S. Kang, D. Kim, H. Lee;

KAIST, Daejeon, KOREA, REPUBLIC OF.

596

Targeted Immobilization of Nanostructures and Biomolecules through Peptide-Based Biolinkers

M. Hnilova¹, C. So¹, E. E. Oren¹, T. Kacar², C. Tamerler², M. Sarikaya¹;

¹GEMSEC, Dept. of Materials Sci. and Engineering, Univ. of Washington, Seattle, WA, ²MOBGAM, Dept. of Molecular Biology, Istanbul Technical Univ., Istanbul, TURKEY.

597

Structural Responses of DNA-DDAB Films to Environmental Triggers

T. Neumann¹, S. Gajria², L. Jaeger², M. Tirrell¹;

¹Univ. of California, Berkeley, Berkeley, CA, ²Univ. of California, Santa Barbara, Santa Barbara, CA.

Engineered In vitro Tissue Model for Disease and Drug Discovery Studies

598

Test System for Modeling Cancer Cell Behavior as a Function of Substrate Stiffness

E. Bland;

Clemson Univ., Clemson, SC.

599

Caco-2 Intestinal Epithelial Model Utilizing Collagen Based Substrates Patterned with Crypt-like Topography

L. Wang¹, S. K. Murthy¹, G. A. Barabino², R. L. Carrier¹;

¹Northeastern Univ., Boston, MA, ²Georgia Inst. of Technology, Atlanta, GA.

600

Extracellular Matrix Surrogates for Tumoroid Generation

V. Sardana, N. Arya, D. Katti;

Indian Inst. of Technology Kanpur, Kanpur, INDIA.

601

Fibroblasts Affect the Phenotype of Normal Human Bronchial Epithelial Cells when Co-cultured in Three-Dimensional (3D) Organotypic Cultures

S. C. Pageau, M. Maffini, A. Soto, C. Sonnenschein;

Tufts Univ., Boston, MA.

602

Sphere-Templated Hydrogels for 3D Observation of Prostate Cancer Cell Growth and Tumor Formation

T. J. Long, C. C. T. Sprenger, S. R. Plymate, B. D. Ratner;

Univ. of Washington, Seattle, WA.

603

In Vitro Tubulogenesis from Cell Lines derived from Embryonic Kidney Modulated by Extracellular Matrices and Growth Factors

X. Zhang, R. Wang, W. Wu, T. Smith, K. T. Bush, S. K. Nigam;

Univ. of California, San Diego, La Jolla, CA.

604

Biofabrication and Cell by Cell Deposition

V. Seshadri, K. J. L. Burg;

Clemson Univ., Clemson, SC.

605

Tissue-Engineered Scaffolds for Screening Nanoparticle - Cell Interactions

K. M. Jeerage, E. Mansfield, T. L. Oreskovic, N. S. Goldstein, T. P. Quinn;

Natl. Inst. of Standards and Technology (NIST), Boulder, CO.

606

Measurement of Tissue Adherence for In Situ Formed PEG Acrylate Hydrogels

S. P. Foster¹, J. Koepsel², T. Butler¹, K. Greenawalt¹, X. Dai¹, J. Colt¹, R. Corazzini¹, O. Syrkina¹, K. Skinner¹, J. Kablik¹, T. Jozefiak¹;

¹Genzyme Corp., Framingham, MA, ²Univ. of Wisconsin-Madison, Madison, WI.

607

Modulating Osteogenesis of Mesenchymal Stem Cells by Modification of Growth Factor Availability

Z. Huang, P-g. Ren, T. Ma, R. S. Lane, S. B. Goodman;

Stanford Univ., Stanford, CA.

608

Microfluidic enabled creation of vascularized 3D miniaturized tissue

X. YANG, J-h. Lee, Y. Wang, W. Lee, H. Wang;

STEVENS Inst. OF TECHNOLOGY, HOBOKEN, NJ.

Engineering Immune Interactions with Biomaterials

609

In Vitro Activation of Dendritic Cells by Polyanhydride Nanoparticles

L. Petersen, A. Yeager, M. Wannemuehler, B. Narasimhan;

Iowa State Univ., Ames, IA.

610

The foreign body response to nerve cuffs is associated with persistent inflammation and changes in nerve fiber composition.

M. B. Christensen, P. A. Tresco;

Univ. of Utah, Salt Lake City, UT.

611

Microelectrodes with Reduced Surface Area Show a Reduced Foreign Body Response

J. L. Skousen¹, B. D. Winslow¹, S. Merriam², O. Srivannavit², G. E. Perlin², K. D. Wise², P. A. Tresco¹;

¹Univ. of Utah, Salt Lake City, UT, ²Univ. of Michigan, Ann Arbor, MI.

612

The role of osteopontin in macrophage mediated inflammation

S. A. Lund, C. Giachelli, M. Scatena;

Univ. of Washington, Seattle, WA.

613

Effects of substratum elasticity on dendritic cell maturation

C. Yacoob, T. Sangvanich, K. Tran, H. Shen;

Univ. of Washington, Seattle, WA.

614

Dendritic Cell Responses to Surfaces Presenting Defined Glycans

N. A. Hotaling¹, P. Kou¹, X. Song², D. Smith², R. Cummings², J. Babensee¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Emory Univ., Atlanta, GA.

615

In Vivo Measurement and Modulation of Cytokine Production in Rats

V. Venkatakrishnan, E. von Grote, J. A. Stenken;

Univ. of Arkansas, Fayetteville, AR.

616

The Effects of Carbon Nanofiber Wettability on Macrophage Functions

Y. Chun, T. J. Webster;

Brown Univ., Providence, RI.

617

Migration Stability of Antioxidant Containing Ultra High Molecular Weight Polyethylene at 75 and 115 kGy Sterilization Doses

A. Senyurt, V. Narayan;

DePuy Orthopaedics, Warsaw, IN.

618

Adhesive Peptide Gradient Regulation of Dendritic Cell Activation

N. D. Gallant¹, A. P. Acharya², B. G. Keselowsky³;

¹Univ. of South Florida, Tampa, FL, ²Univ. of Florida, Gainseville, FL, ³Univ. of Florida, Gainesville, FL.

619

Determination and modulation of reactive oxygen species production and release by human peripheral blood-derived monocytes adhered to poly(ethylene glycol)-based materials

H. Waldeck, W. J. Kao;

Univ. of Wisconsin - Madison, Madison, WI.

620

Parallel Particle Production & Cellular Arrays For Particle-Vaccine Development And Optimization

A. P. Acharya, N. Dolgova, J. Lewis, M. J. Clare-Salzler, C-Q. Xia, B. G. Keselowsky;

Univ. of Florida, Gainesville, FL.

Engineering Therapeutic Delivery from Biomaterial Scaffolds for Cell Therapy

621

Novel approach for anchoring bioactive peptides to bone regenerative biomaterials

B. K. Culpepper, S. L. Bellis;

Univ. of Alabama at Birmingham, Birmingham, AL.

622

Transfected Stem Cell Delivery via Thermoreversible Hydrogel for Improved Cardiac Function

B. A. Borden, J. Yockman, S. Kim;

Univ. of Utah, Salt Lake City, UT.

623

Enhanced Islet Function and Survival of Rat Islets in a Biomimetic Self-assembled Nanomatrix Gel

D-J. Lim, S. Antipenko, J. Anderson, K. Jaimes, B. Stephen, S. Bryant, B. Yancey, J. Contreras, J. Thompson, J. Corbett, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

624

Controlling Monocyte Differentiation to Treat Ectopic Calcification

A. Moreno-Gonzalez¹, T. Osathanon², M. Scatena¹, C. M. Giachelli¹;

¹Univ. of Washington, Seattle, WA, ²Chulalongkorn Univ., Bangkok, THAILAND.

625

Polymer - Xerogel Composites for Controlled Release Wound Dressings: a Rat Incisional Pain Model Study

H. Qu¹, M. Costache², D. Devore², P. Ducheyne³;

¹Univ. of Pennsylvania, Philadelphia, PA, ²Rutgers, the State Univ. of New Jersey, New Brunswick., NJ, ³Dept. of Bioengineering, Univ. of Pennsylvania, Philadelphia, PA.

626

A Collagen-Chitosan Scaffold as a Possible Highly Vascularized Ectopic Site for Pancreatic Islet Transplantation

B. Vulesevic¹, C. Deng¹, C. Ellis², G. S. Korbutt², E. J. Suuronen¹;

¹Univ. of Ottawa Heart Inst., Ottawa, ON, CANADA, ²Alberta Diabetes Inst., Edmonton, AB, CANADA.

627

Site-Specific Osteoclast-Mediated Cell Therapy for Vascular Calcification

C. L. Simpson, C. Cheluvaraju, N. Vyavahare;

Clemson Univ., Clemson, SC.

Engineering Vascularized Tissues

628

Colloidal microgels for neovascularization

R. J. DeVolder, H. Kong;

Univeristy of Illinois, Urbana, IL.

629

Bio-Artificial Matrices for Therapeutic Vasularization

E. A. Phelps¹, N. Landázuri², P. M. Thulé³, W. R. Taylor⁴, A. J. García¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Emory Univ., Atlanta, GA, ³Atlanta VA Med. Ctr., Emory Univ., Atlanta, GA, ⁴Atlanta VA Med. Ctr., Emory Univ., Georgia Inst. of Technology, Atlanta, GA.

630

Modulating the Biological Milieu Within Cardiovascular Biomaterials using Novel Constructs Derived from Fibronectin

M. Sobel, T. R. Kohler, J. Murray, M. Namekata, M. Yagi, E. S. Wijelath;

VAPSHCS and Univ. of Washington, Seattle, WA.

631

Photolithographically and Softlithographically Microfabricated Poly(ethylene glycol) Hydrogels

M. Cuchiara, J. Miller, A. Allen, T. Chen, R. Villareal, J. West;

Rice Univ., Houston, TX.

632

Microchanneled and Microporous Fibrin Scaffolds for Cardiac Tissue Engineering

K. S. Thomson, G. D. Robinson, F. S. Korte, M. Linnes, C. M. Giachelli, B. D. Ratner, M. Regnier, M. Scatena;

Univ. of Washington, Seattle, WA.

633

Guided Endothelial Cell Growth in Three-dimensional Hydrogels

Y. Aizawa, M. Shoichet;

Univ. of Toronto, Toronto, ON, CANADA.

634

Identification of crosstalk between inflammation and angiogenesis in bioactive hydrogels

A. L. Zachman¹, C. K. Griffith², S. W. Crowder¹, S. Patel², J. Kohn², H-J. Sung¹;

¹Vanderbilt Univ., Nashville, TN, ²Rutgers Univ., Piscataway, NJ.

635

A Poloxamine-Polylysine Acrylate Scaffold for Modular Tissue Engineering

E. Ciucurel, M. V. Sefton;

Univ. of Toronto, Toronto, ON, CANADA.

636

A Laminated Perfusion Channel Scaffold for Creating Thick Tissue Engineered Constructs

J. P. Kennedy, L. M. Williams, S. P. McCandless, R. W. Htichcock;

Univ. of Utah, Salt Lake City, UT.

Glycosaminoglycan Biomaterials in Medicine

637

Characterization of and Cellular Response to Changes in Composition of a Hyaluronic Acid-Based Hydrogel

K. Davis, C. Clavijo, A. dePoix, B. Mann;

Univ. of Utah, Salt Lake City, UT.

638

Mast cells in chitosan-mediated wound healing

M. Jung¹, M. S. Lord¹, S. McCarthy², J. M. Whitelock¹;

¹The Univ. of New South Wales, Sydney, AUSTRALIA, ²HemCon Med. Technologies Inc, Portland, OR.

639

Incorporation of Theophylline in a hydrogel based on polyelectrolyte complex of chitosan/chondroitin sulfate: mechanical properties and release profiles at different pH conditions

E. C. Muniz, Sr., L. C. Lopes, J. F. Piai, A. R. Fajardo, A. F. Rubira;

Univ.e Estadual de Maringá, Maringá, BRAZIL.

640

Platelet adhesion to chitosan mediates wound healing through proteoglycans and integrin receptors

B. Cheng¹, M. S. Lord¹, S. McCarthy², J. M. Whitelock¹;

¹The Univ. of New South Wales, Sydney, AUSTRALIA, ²HemCon Med. Technologies Inc, Portland, OR.

Immunology of Nanomaterials

641

The Effect of Cytotoxic Particles on Cell Damage Molecule Release and Pattern Recognition Receptor Activation

E. L. Nalvarte-Kostoryz, C. L. Mo, A. E. Holt, M. P. Walker, J. H. Purk, J. D. Eick;

Univ. of Missouri-Kansas City, Kansas City, MO.

642

Macrophage Response to Nanometer-Size Chromium Oxide Particles

R. VanOs, P. E. Beaulé, I. Catelas;

Univ. of Ottawa, Ottawa, ON, CANADA.

643

Immunomodulatory Polyanhydride Particle Vaccines to Provide Protection Against Plague

B. D. Ulery¹, D. Kumar², M. J. Wannemuehler¹, D. W. Metzger², B. Narasimhan¹;

¹Iowa State Univ., Ames, IA, ²Albany Med. Coll., Albany, NY.

644

Blood Interaction and Protein Adsorption on Engineered Titania Nanotubular Arrays

B. S. Smith¹, S. Yoriya², C. A. Grimes², K. C. Popat¹;

¹Colorado State Univ., Fort Collins, CO, ²Penn State, State College, PA.

Implant Pathology SIG

645

Histology of Allograft-Prosthesis Composites for Reconstruction in Severe Bone Loss of the Proximal Femur

E. L. Dahlmeier, R. M. Urban, D. J. Hall, C. J. Della Valle, J. O. Galante, J. J. Jacobs;

Rush Univ. Med. Ctr., Chicago, IL.

646

Effects of radiation therapy on silicone prostheses with different gel cohesivity

L. Altomare¹, L. Lozza², C. Stucchi², M. Tanzi¹, M. Nava², S. Fare'¹;

¹Politecnico di Milano, Milan, ITALY, ²Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, ITALY.

647

Modifying Macrophage Activation and the Foreign Body Response to PEG-based Hydrogels

A. D. Lynn, T. R. Kyriakides, L. M. Johnson, C. N. Bowman, S. J. Bryant;

Univ. of Colorado at Boulder, Boulder, CO.

648

Precision Staining of Histological Samples Using Thermal Inkjet Technology

M. E. Pepper, C. A. P. Cass, T. C. Burg, R. E. Groff, L. L. Jenkins, K. J. L. Burg;

Clemson Univ., Clemson, SC.

Micron and Nanotechnology Derived Theranostic Biomaterials

649

Development of Multifunctional Lipid-Pluronic Nanobubble Ultrasound Contrast Agents

T. M. Krupka, R. E. Wilson, L. Solorio, H. Wu, N. Azar, A. A. Exner;

Case Western Reserve Univ., Cleveland, OH.

650

Nanoparticulate Gold-Polymer Systems for Externally-Controlled Delivery

M. L. Gran, N. A. Peppas;

Univ. of Texas at Austin, Austin, TX.

651

Methodology of Biodegradable Photoluminescent Polymer Development

Y. Zhang, J. Yang;

Univ. of Texas at Arlington, Arlington, TX.

652

Biofilm-Degrading Enzyme Delivery from Chitosan Nanoparticles

L. N. Strotman, A. S. Gobin;

Univ. of Louisville, Louisville, KY.

653

Multifunctional Calcium Phosphate Nanocomposite for Synchronous Sensing and Controlled Drug Delivery

S. Banerjee, S. Bose;

Washington state Univ., Pullman, WA.

654

Specific protein binding on fluidic lipid bilayer microarray corralled by well-defined polymer brushes

Y. Iwasaki¹, K. Nakai¹, K. Morigaki²;

¹Kansai Univ., Osaka, JAPAN, ²Kobe Univ., Hyogo, JAPAN.

655

Solid Phase Synthesis of Thermally Responsive Dendritic Macromolecules for Drug Delivery Purposes

K. Chang, L. A. Bergman, L. J. Taite;

Georgia Inst. of Technology, Atlanta, GA.

Models of Cardiovascular Materials Biocompatibility

656

Evaluation of a degradable polar hydrophobic ionic polyurethane designed for vascular graft generation in an in vivo mouse model

S. M. McDonald¹, L. A. Matheson¹, J. E. McBane², S. Sharifpoor², J. P. Santerre²;

¹Univ. of Ottawa Heart Inst., Ottawa, ON, CANADA, ²Univ. of Toronto, Toronto, ON, CANADA.

657

Validation of a Novel Flow Circuit Assessing Vascular Biomaterials Retention of Endothelial Cells

S. Dimitrievska, Jr., M. N. Bureau, Sr.;

Natl. Res. Council Canada, Boucherville, QC, CANADA.

658

Full-Blood Thrombin Generation Time: A Blood Coagulation Assay as Alternative for aPTT and PT using Flowing Blood.

M. L. W. Knetsch, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.

Molecular Mechanisms Mediating Protein-Surface and Cell-Surface Interactions

659

Activation of Cyclic Adenosine Monophosphate/Protein Kinase A Signaling Pathway Enhances Osteoblast Cell adhesion on Biomaterials for Bone Tissue Engineering Application

W. Lo, C. T. Laurencin;

Univ. of Connecticut Hlth.center, Farmington, CT.

660

Adsorption and Activity of Fibrinogen on Polyurethane Biomaterials Surfaces in the Presence of Other Proteins

L. XU, C. Siedlecki;

Penn State Univ. Coll. of Med., Hershey, PA.

661

Correlation Between Desorption Force Measured by Atomic Force Microscopy (AFM) and Adsorption Free Energy Measured by Surface Plasmon Resonance (SPR) for peptide-surface interactions

Y. Wei, R. A. Latour;

clemson Univ., Clemson, SC.

662

Computational Modeling of Biological Responses For a Large Library of Poly(methacrylates)

J. Ghosh¹, D. D. Knight², J. Kohn¹;

¹New Jersey Ctr. for Biomaterials, Rutgers, Piscataway, NJ, ²Rutgers - The State Univ. of New Jersey, Piscataway, NJ.

663

Mechanisms of the Angiogenic Effect of Poly(Methacrylic Acid-co-Methyl Methacrylate) Beads

L. E. Fitzpatrick, M. V. Sefton;

Univ. of Toronto, Toronto, ON, CANADA.

664

Structural Bioinformatics Based Method for Predicting the Initial Adsorbed Protein Orientation on a Surface

A. A. Thyparambil, R. A. Latour;

Clemson Univ., Clemson, SC.

665

Calculation of Free Energy of Peptide-Surface Interactions Using Biased -Sampling Molecular Dynamics

N. A. Vellore, J. A. Yancey, S. J. Steven, R. A. Latour, Jr.;

Clemson Univ., Clemson, SC.

666

Monocyte phenotypic polarization on PEG hydrogels, polydimethylsiloxane, and TCPS is mediated by exogenous serum and surface-associated proteins including complement C3, fibrinogen, thrombin, and vitronectin

W. Kao, D. Schmidt, E. Joyce, X. Wang;

Univ. of Wisconsin - Madison, Madison, WI.

667

Controlling Cell Behavior in a Hydrogel Environment by Genetic Modification

S. Sahai;

Univ. of South Carolina, Columbia, SC.

668

Simulated Interactions between Structured Peptides and Biomaterials

G. Collier, S. J. Stuart, R. A. Latour;

Clemson Univ., Clemson, SC.

669

Effect of Pressure on Adsorption Free Energy in Protein Adsorption Simulations

J. A. Yancey, N. A. Vellore, S. J. Stuart, R. A. Latour;

Clemson Univ., Clemson, SC.

670

Conformational stability of proteins conjugated with water-soluble phospholipid polymer from heat-induced denaturation: Effect of the hydrophilicity of the polymer materials

J-H. Seo, R. Matsuno, Y. Lee, T. Konno, M. Takai, K. Ishihara;

The Univ. of Tokyo, Tokyo, JAPAN.

671

Poly(ε-caprolactone) Acrylate Networks with Controllable Properties and Tunable Cell Behavior

S. Wang, L. Cai;

The Univ. of Tennessee, Knoxville, TN.

672

Poly(ε-caprolactone) Homo-Blends with Controllable Properties and Cell Behavior

S. Wang, K. Wang;

The Univ. of Tennessee, Knoxville, TN.

673

Significant Parameters for Protein Adsorption on Well-controlled Polymer Brush Surface

T. Nakanishi, Y. Inoue, R. Matsuno, M. Takai, K. Ishihara;

the Univ. of Tokyo, Dept. of Materials Engineering, Hongo, JAPAN.

674

Biomimetic polymer brushes to control protein-surface interactions

R. V. Lerum, H. Bermudez;

Univ. of Massachusetts Amherst, Amherst, MA.

675

Cathodic Voltage Preconditioning of Ti-6Al-4V in Media Affects MC3T3 Pre-Osteoblast Cell Viability

S. Sivan, E. S. Ouellette, J. L. Gilbert;

Syracuse Univ., Syracuse, NY.

Multi-factor Drug Delivery for Musculoskeletal Regeneration

676

Concurrent Release of BMP-2 and Gentamicin in an Infected Open Fracture Model

R. L. Stewart¹, J. T. Cox¹, L. Kenan¹, D. Volgas¹, J. Stannard¹, L. Duffy¹, K. B. Waites¹, T-M. G. Chu²;

¹Univ. of Alabama at Birmingham, Birmingham, AL, ²Indiana Univ. Sch. of Dentistry, Indianapolis, IN.

677

Effectiveness of a Dual Drug Delivery Calcium Sulfate, Chitosan-Calcium Phosphate Bone Scaffold.

H. Doty, W. Haggard, H. Courtney, J. Bumgardner;

Univ. of Memphis, Memphis , TN.

678

Characterization of a Two-Phase Drug Delivery System to Treat Perthes Disease

Y. Zou, J. L. Brooks, T. A. Milbrandt, V. Talwalkar, D. A. Puleo;

Univ. of Kentucky, Lexington, KY.

679

Controlled drug release from hydroxyapatite-coated porous metal structure

G. GUPTA, A. Bagadia, S. Sundaramurthy;

BIOMET INC., WARSAW, IN.

Nano Materials

680

Stimuli-Responsive “Smart” Magnetic Nanoparticles for Point-of-Care Diagnostics

J. J. Lai, A. S. Hoffman, P. S. Stayton;

Univ. of Washington, Seattle, WA.

681

Noncovalent Modification of Proteins Using Smart Polymer: Implications in Modulating Enzymatic Activity and Improvement of Thermotorelant Property

S. Ganguli, IV, K. Yoshimoto, IV, S. Tomita, IV, H. Sakuma, IV, T. Matsuoka, IV, K. Shiraki, IV, Y. Nagasaki, IV;

Univ. of Tsukuba, Tsukuba, JAPAN.

682

Preparation of A Magnetically Attracted Poly(N-isopropylacrylamide)-Based Stimuli-Responsive Coacervate for Bioseparations

T. Maeda¹, Y. Kodama², K. Yamamoto², T. Aoyagi¹;

¹Natl. Inst. for Materials Sci., Tsukuba, JAPAN, ²Kagoshima Univ., Kagoshima , JAPAN.

683

A Novel Approach to Preparing Multi Stimuli-Responsive Nano-Assembly by A Simple Mixing of Block Copolymers

Y. Kotsuchibashi¹, M. Ebara¹, K. Yamamoto², T. Aoyagi¹;

¹Natl. Inst. for Materials Sci., Tsukuba, JAPAN, ²Kagoshima Univ., Kagoshima , JAPAN.

684

A Rapid Test for Malaria Utilizing a “Smart” Microfluidic Concentrator and Immunoassay

A. L. Golden¹, C. F. Battrell², A. S. Hoffman¹, P. S. Stayton¹;

¹Univ. of Washington, Seattle, WA, ²Micronics, Inc., Redmond, WA.

685

Grafting of PMMA brushes on cross-linked PMMA nanospheres for use in novel two-solution bone cements

D. C. Rodrigues, R. Bader, J. M. Hasenwinkel;

Syracuse Univ., Syracuse, NY.

686

Evaluate the cell adhesion force for HOS and fibroblast on the nano-metric roughness of Ti6Al4V

M-C. Hsieh, C-C. Wang, T-M. Lee, S-P. Yang;

Natl. Cheng Kung Univ., Tainan, TAIWAN.

687

Decreased Staphylococcus aureus activity in the presence of iron oxide magnetic nanoparticles

N. Tran, T. Webster;

Brown Univ., Providence, RI.

688

Surface functionalized carbon nanopipettes for real-time intracellular signaling sensing

S. Bhattacharyya¹, M. Schrlau², H. Bau¹, P. Ducheyne¹;

¹Univ. of Pennsylvania, Philadelphia, PA, ²Drexel Univ., Philadelphia, PA.

689

Antibacterial Properties of Sonicated Piezoelectric Zinc Oxide Nanoparticles

J. T. Seil, E. N. Taylor, T. J. Webster;

Brown Univ., Providence, RI.

690

Evaluation of ultra thin PIPAAm layer modified glasscover slips surfaces by using AFM

Y. AKIYAMA¹, K. Fukumori², M. Yamato³, T. Okano¹;

¹Tokyo Women`s Med. Univ., 8-1 Kawadacho, Shinjuku-ku, Tokyo, JAPAN, <sup>2</sup>Dept. of Applied Chemistry, Waseda Univ., 3-4-1 Ohkubo, Shinjuku, Tokyo, JAPAN, <sup>3</sup>Inst. of Advanced BioMed. Engineering and Sci., Tokyo Women`s Univ., 8-1 Kawadacho, Shinjuku-ku, Tokyo, JAPAN.

691

Assembly of Alumina Nanoparticles Using Engineered Protein Linker

N. Chopra¹, P. Nednoor², J. Li², Y. Wei², V. G. Gavalas², L. G. Bachas²;

¹The Univ. of Alabama, Tuscaloosa, AL, ²The Univ. of Kentucky, Lexington, KY.

692

Characteristics of DSPE-PEG2000 Self Assemblies in Pure Water and Isotonic Buffer Solution

S. P. Drake, K. S. Brandenburg, S. Lim, H. Onyuksel;

Univ. of Illinois at Chicago, Chicago, IL.

693

Local Environment Effects on Silver Nanoparticle Antimicrobial Activity

B. J. Dair, D. M. Saylor, S. K. Pollack;

US Food and Drug Admin., Silver Spring, MD.

694

Plasma Protein Interactions with Bovine Serum Albumin Nanoparticles

M. S. Bahniuk;

Univ. of Alberta, Edmonton, AB, CANADA.

695

Design Optimization, Characterization, and Bioactivity Assessment of nanocomposite scaffold

A. M. El-kady, M. M. Farag, B. M. Abd El-Hadya;

Natl. Res. Ctr., Cairo, EGYPT.

696

Masking and Triggered 'Unmasking' of Targeting Ligands Improves Liposomal Delivery to Glioma

K. McNeeley¹, E. Karathanasis², A. Annapragada³, R. Bellamkonda¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Case Western Reserve Univ., Cleveland, OH, ³Univ. of Texas Hlth.Sci. Ctr., Houston, TX.

697

Synthesis of Biodegradable Nucleic Acid Carriers by RAFT Copolymerization of Cationic Peptides with HPMA

R. N. Johnson, R. S. Burke, A. J. Convertine, A. S. Hoffman, P. S. Stayton, S. H. Pun;

Univ. of Washington, Seattle, WA.

698

Novel Translucent/Transparent Thermoplastic Elastomeric Nanocomposites for Breast Prosthesis

G. Lim¹, S. E. Porosky², C. Götz³, V. Altstädt³, J. E. Puskas¹;

¹Dept. of Polymer Sci., Akron, OH, ²Univ. of Akron, Akron, OH, ³Dept. of Polymer Engineering, Univ. of Bayreuth, Bayreuth, GERMANY.

699

Stability of Biodegradable Peptide Nanospheres with PEG Brush Layer for Hydrolysis and Sterilization

M. MATSUMOTO, T. WAKU, M. MATSUSAKI, M. AKASHI;

Graduate Sch. of Engineering, Osaka Univ., Suita, JAPAN.

700

Addition of Silicate Nanoparticles to Poly(ethylene oxide) Controls Cell Adhesion

P. Schexnailder, A. K. Gaharwar, G. Schmidt;

Weldon Sch. of BioMed. Engineering, West Lafayette, IN.

Natural-based Polymeric Biomaterials and Composites

701

Biomimetic Design of Calcium Phosphate- reinforced Collagen Hydrogels for Bone Tissue Engineering

X. Chen;

Stevens Inst. of Technology, Hoboken, NJ.

702

Alginate Skin Wound Dressing Manufactured by Rapid Prototyping Technique

H-Y. Lin, Y-H. Wang;

Natl. Taipei Univ. of Technology, Taipei, TAIWAN.

703

Chitosan enhances adhesion and proliferation of osteoblast cells on nanocomposite films

A. K. Gaharwar, P. Schexnailder, Q. Jin, C-J. Wu, G. Schmidt;

Purdue Univ., West Lafayette, IN.

704

In Vivo Study of Chitosan-Silica Xerogel Hybrid Membrane for Wound Healing

E-J. Lee, H-E. Kim;

seoul Natl. Univ., seoul, KOREA, REPUBLIC OF.

705

Aligned Collagen-GAG Scaffolds for Tendon Tissue Engineering

S. R. Caliari, M. Ramirez, B. A. C. Harley;

Univ. of Illinois at Urbana-Champaign, Urbana, IL.

706

Effect of Molecular Weight of Chitosan Degraded by Microwave Irradiation on Bone Tissue Engineering Applications

M. M. Mecwan, T. Burkey, S. R. Mishra, W. O. Haggard, J. D. Bumgardner;

Univ. of Memphis, Memphis, TN.

707

Collagen Matrix possessing similar structure of that of native extracellular matrix

K. Nam, Y. Sakai, T. Kimura, A. Kishida;

Div. of Biofunctional Molecules, Inst. of Biomaterials and Bioengineering,, Tokyo, JAPAN.

708

Effectiveness of a Novel Poly(Urea-Urethane) as an Antimicrobial and in Reducing Inflammation and Pain

L. L. Swick, J. C. Leung, S. E. Neuville;

Chesson Lab. Associates, Inc., Durham, NC.

709

Bulk Biomineralization of Dense Fibrillar Collagen-Bioglass® Hybrid Scaffolds

B. Marelli¹, C. E. Ghezzi¹, J. E. Barralet¹, A. R. Boccaccini², S. N. Nazhat¹;

¹McGill Univ., Montreal, QC, CANADA, ²Friedrich-Alexander-Univ. Erlangen, Nürnberg, GERMANY.

710

Integrin-Mediated Platelet Adhesion as a Mechanism for Hemostatic Activity of a Keratin Biomaterial.

M. Bahawdory¹, L. Burnett², R. R. Hantgan³, M. E. Van Dyke¹;

¹Wake Forest Inst. for Regenerative Med., Winston Salem, NC, ²Keranetics, Winston Salem, NC, ³Wake Forest Univ. Sch. of Med., Winston Salem, NC.

711

Mechanical Properties of Hydroxyapatite Reinforced Collagen Scaffolds

R. J. Kane, R. K. Roeder;

Univ. of Notre Dame, Notre Dame, IN, IN.

712

Novel Electro-spray Technique for Applying Phospholipid Coatings to Titanium

D. A. Prawel, K. C. Popat, S. P. James;

Colorado State Univ., Ft. Collins, CO.

713

Preparation and characterization of microspheres constituted of Zein and Chitosan, as polymeric biomaterial

E. C. Muniz, Sr., V. Muller, Sr., J. F. Piai, A. R. Fajardo, Sr., S. L. Favaro, A. F. Rubira, Sr.;

Univ.e Estadual de Maringá, Maringá, BRAZIL.

714

Development of a Novel in situ forming Tissue Engineering Scaffold

A. Agawu, S. Banerjee, A. P. Desai, T. D. Sargeant, J. B. Stopek;

Covidien, North Haven, CT.

715

Adhesive and Proliferative Response of Primary Mouse Dermal Fibroblasts to Human Hair Keratins: An in vitro Wound Healing Evaluation

C. V. Gaines, M. Van Dyke;

Wake Forest Inst. for Regenerative Med., Winston-Salem, NC.

716

Biomechanical Strength Comparison of Unidirectional and Bidirectional Barbed Wound Closure Devices in Dermal Incisions

K. Gingras, J. Zaruby, R. Pennoyer;

Covidien, North Haven, CT.

717

Evaluation of Two Osteochondral Constructs for Osteochondral Tissue Engineering

D. T. Nguyen¹, S. Maxson², K. J. L. Burg², J. D. Bumgardner¹;

¹Univ. of Memphis, Memphis, TN, ²Clemson Univ., Clemson, SC.

718

Evaluation of osteogenic differentiation of rat marrow mesenchymal stromal cells on the biomineral/agarose composite gels

Y. Suzawa¹, N. Mizuta¹, T. Funaki², S. Iwai¹, Y. Yura¹, T. Nakano², H. Ohgushi³, M. Akashi⁴;

¹Dept. of Dentistry,Osaka Univ., Osaka, JAPAN, ²Graduate school of Engineering,Osaka Univ., Osaka, JAPAN, ³Res. Inst. for Cell Engineering, Natl. Inst. of Advanced Industrial Sci. and Technology, Hyogo, JAPAN, ⁴Graduate Sch. of Engineering,Osaka Univ., Osaka, JAPAN.

719

Photocrosslinkable Collagen-Polyethylene Glycol Hybrid Hydrogels for in situ Modification of Scaffold Stiffness

I. Gaudet, D. I. Shreiber;

Rutgers Univ., Piscataway, NJ.

720

Tailoring the Mechanical & Bio-Response Properties of a Natural Tissue Adhesive Using Pharmaceutical Excipients

G. Tomer, O. Preiss Bloom;

LifeBond, Caesarea, ISRAEL.

721

Chitosan-polycaprolactone based miscible polyblend nanofibrous conduit for peripheral nerve regeneration

N. Bhattarai;

Univ. of Washington, Seattle, WA.

Novel Approaches for Rapid Prototyping of Biomaterials

722

Fabrication of Tissue Chip by Layer-by-Layer Inkjet Printing

K. Sakaue, K. Kadowaki, M. Matsusaki, M. Akashi;

Graduate Sch. of Engineering, Osaka Univ., Suita, JAPAN.

723

3D Printing of an Elastic Lamellar Scaffold for Intervertebral Disc Regeneration

B. R. Whatley¹, Y. Qiu¹, B. Damon², J. Kuo¹, X. Wen¹;

¹Clemson Univ., Charleston, SC, ²Med. Univ. of South Carolina, Charleston, SC.

724

In Situ Gelatinization Manufacturing of Fibrin Blood Vessel Scaffolds

Z. Xiong, C. Weng, T. Zhang, S. Li, R. Zhang, Y. Yan;

Dept. Mechanical Engineering, Tsinghua Univ., Beijing, CHINA.

725

Fabrication, Mechanical and In vitro Biological Properties of Porous Tantalum for Bone Implants

A. Bandyopadhyay, V. K. Balla, S. Bodhak, S. Bose;

Washington State Univ., Pullman, WA.

726

Reversibly Crosslinked Gold Nanoparticle - Hyaluronan Hydrogels for Automated Vessel Construct Bioprinting

A. Skardal, J. Zhang, L. McCoard, S. Oottamasathien, G. D. Prestwich;

Univ. of Utah, Salt Lake City, UT.

727

Fabrication of 3D Scaffolds by Two-Photon Polymerization

A. Ovsianikov¹, M. Gruene¹, L. Koch¹, M. Pflaum², M. Wilhelmi², A. Haverich², S. Gittard³, R. Narayan³, B. Chichkov¹;

¹Laser Zentrum Hannover e.V., Hannover, GERMANY, ²Medizinische Hochschule Hannover, Hannover, GERMANY, ³Joint Dept. of BioMed. Engineering, North Carolina State University, Raleigh, NC.

728

Wear Resistance Improvement by Laser Deposited Ti/TiC Coating

D. Justin¹, Y. YANG², B. Stucker²;

¹IMDS Co-Innovation, LOGAN, UT, ²UTAH STATE Univ., LOGAN, UT.

729

Recent Developments in Tissue Engineering using the 3D-Bioplotter™

C. Carvalho, R. van Bernum, A. Siblani;

Envisiontec GmbH, Gladbeck, GERMANY.

730

A Systematic Method to Quantify Cell Viability in the Bio-Manufacturing Process

X. B. Chen;

Univ. of Saskatchewan, Saskatoon, SK, CANADA.

731

Laser Direct Writing of Mouse Embryonic Stem Cells Encapsulated in Alginate Microbeads

Y. Xie¹, N. Abdul Raof¹, T. Phamduy², X. Guo³, N. R. Schiele², D. B. Chrisey², D. T. Corr²;

¹Univ. at Albany, SUNY, Albany, NY, ²Rensselaer Polytechnic Inst., Troy, NY, ³Berkshire Sch., Sheffield, MA.

732

A biomimetic ‘sensate’ uni-condylar replacement scaffold for knee joint resurfacing

J. A. Szivek, C. P. Geffre, M. J. Marini, G. J. Heden, P. A. Sante Cruz;

Univ. of Arizona, Tucson, AZ.

733

Simulation of Excimer Laser Microfabricated Tissue Engineering Scaffold Microstructural Deformations and Effective Stiffness

G. C. Engelmayr, Jr., A. Jean;

The Pennsylvania State Univ., University Park, PA.

734

Laser Micromachining of Differentially-Adherent Substrates to Direct Cellular Growth for Functional Tissue Engineering

D. T. Corr, N. R. Schiele, R. A. Koppes, D. B. Chrisey;

Rensselaer Polytechnic Inst., Troy, NY.

735

Design and Fabrication of Implants for Amputation Prosthesis

A. Bandyopadhyay, P. DeVasConCellos, V. K. Balla, S. Bose, W. S. Dernell;

Washington State Univ., Pullman, WA.

736

Effect of Porosity on Mechanical Properties and Biological Response of 3D Periodic Porous Titanium

N. Hrabe¹, R. Fernandes¹, P. Heinl², C. Koerner², R. Bordia¹;

¹Univ. of Washington, Seattle, WA, ²Univ. of Erlangen-Nuremberg, Erlangen, GERMANY.

737

Laser printing of multi-cellular patterns with adjustable cell densities

M. Gruene¹, A. Deiwick², S. Schlie¹, L. Koch¹, N. Hofmann², B. Glasmacher², B. N. Chichkov¹;

¹Laser Zentrum Hannover e.V., Hannover, GERMANY, ²Leibniz Univ., Inst. für Mehrphasenprozesse, Hannover, GERMANY.

Novel Imaging Methods for Mapping Cell Phenotype

738

Towards a Representative Phenotypic Representation of Structural Components of Vascular Smooth Muscle Cells

S. T. Wood, B. Dean, D. Dean;

Clemson Univ., Clemson, SC.

Ocular Drug-Delivery - A Unique Platform for Advanced Drug Administration

739

Thermosensitive, Injectable, Biodegradable Polymers for Ocular Drug Delivery

S. Garty¹, N. Kim², A. Galperin¹, S. Kanayama², T. T. Shen², B. D. Ratner¹;

¹Bioengineering, Univ. of Washington, Seattle, WA, ²Ophthalmology, Univ. of Washington, Seattle, WA.

740

Photoresponsive Hydrogels for Ophthalmic Drug Delivery

L. A. Wells, H. Sheardown;

McMaster Univ., Hamilton, ON, CANADA.

741

Preliminary in-vitro and in-vivo evaluation of Paclitaxel from glaucoma drainage device

Y. Kwon¹, E. Arrieta², Y. P. Kato¹, M. Orozco¹, M. Aguilar², Y. Zhou¹, L. Pinchuk¹, J-M. Parel²;

¹Innovia-LLC, Miami, FL, ²Bascom Palmer Eye Inst., the Univ. of Miami, Miami, FL.

742

Decreasing Apoptosis in Diabetic Retina with Subconjunctivally Implanted Hydrogels: One Step toward Potential Treatment of Diabetic Retinopathy

G. Misra¹, H. Imai², T. Gardner², T. Lowe¹;

¹Thomas Jefferson Univ., Philadelphia, PA, ²Penn State Univ. Coll. of Med., Hershey, PA.

743

Controlled Release of Drugs for Cataract Surgery from an Engineered Hydrogel Device

F. B. Karp¹, S. Garty², T. T. Shen², B. D. Ratner²;

¹Inson Med. Systems, Inc., Bellevue, WA, ²Univ. of Washington, Seattle, WA.

Orthopaedic Biomaterials SIG

745

In vivo response of novel calcium phosphate-mullite composites: results upto 12 weeks of implantation

S. Nath¹, B. Basu¹, M. Mohanty², P. V. Mohanan²;

¹Indian Inst. of Technology Kanpur, Kanpur, INDIA, ²Sree Chitra Tirunal Inst. for Med. Sci. and Technology, Trivandrum, INDIA.

746

Cytocompatibility and Phase Assemblage Study of Heat Treated Potassium Magnesium Phosphate-Silicate Ceramics

B. Basu, R. Kumar;

Indian Inst. of Technology, Kanpur, Kanpur, INDIA.

747

Effect of Inclusion of Microparticle Fillers on Mechanical Properties of PEG-based Hydrogels

M. N. Tapp, A. Tsukruk, K. Gall, J. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.

747

Dendrimer Hydrogels for Mucoadhesive Ocular Drug Delivery

C. A. Holden, H. Yang;

Virginia Commonwealth Univ., Richmond, VA.

748

Co-alloy Particles (DAMP’s) Induce Stronger Inflammasome Activation (IL-1β) in Early Macrophages Compared to Fully Differentiated Macrophages

M. S. Caicedo;

Rush Univ. Med. Ctr., Chicago, IL.

749

Wear characterization of a metal-on-metal cervical disc under ISO and ASTM test conditions

M. L. Harper, V. Singh, F. W. Chan;

Medtronic, Inc., Memphis, TN.

750

Electrochemical Properties of Titanium Under Cathodic Polarization and Simulated Inflammatory Conditions

M. T. Ehrensberger, G. Rudolph, A. Sobel, V. Capanelli;

Univ. At Buffalo, Buffalo, NY.

751

Wear of Metal-on-Metal, Si3N4-on-Metal, Ceramic-on-Metal and Ceramic-on-Ceramic in a Hip Simulation Study

Y-S. Liao, A. Alberts, T. Render;

DePuy Orthopaedics, Inc., Warsaw, IN.

752

Wear Simulation of High-Flexion Activities of Daily Living: Stair Climbing in Displacement Control

J. L. Tikka, T. Render, M. R. Dressler, S. Swope;

DePuy Orthopaedics Inc., Warsaw, IN.

753

A Highly Sensitive Method for Isolation and Display Metallic Debris from Synovial Fluid

F. Billi, P. Benya, A. Kavanaugh, H. A. McKellop, J. V. Luck, Jr.;

Orthopaedic Hosp. UCLA, Los Angeles, CA.

754

Development of a Biomechanical Model to Evaluate Mechanically-Induced Corrosion of Stainless Steel Posterior Lumbar Spinal Implants

J. L. Turner¹, P. E. Pare¹, R. Vance², J. L. Gilbert³, B. Wilcox¹, J. Mirda¹;

¹Medtronic's Spinal and Biologics Business, Memphis, TN, ²Univ. of Utah, Salt Lake City, UT, ³Syracuse Univ., Syracuse, NY.

755

Characterization of wear particles from periprosthetic tissues from total hip patients

M. K. Musib, V. Rasquinha, S. Saha;

SUNY Downstate Med Ctr., Brooklyn, NY.

756

Preparation of Artificial Biological Ligament and Experiment in vivo and Cell Culture.

F. Y. Zhong;

Clemson Univ., Clemson, SC.

757

Choosing the Appropriate Material for Orthopaedic Instrumentation

J. L. Cartner, A. Whitten, R. L. Soileau;

Smith & Nephew, Memphis, TN.

758

Biocompatible Phospholipid Polymer Grafting Improves the Wear Resistance of Artificial Hip Joints Regardless of the Degree of Cross-linking

T. Moro, Y. Takatori, K. Ishihara, M. Kyomoto, T. Karita, H. Ito, T. Tsunoda, K. Saiga, K. Nakamura, H. Kawaguchi;

The Univ. of Tokyo, Tokyo, JAPAN.

759

Evaporative Assembly of Drug-Eluting Bioresorbable Nanocomposite Micropatterns

Y. Gu, W. Lee, J-H. Lee, A. Ihnen;

Stevens Inst. of Technology, Jersey City, NJ.

760

Porous titanium scaffolds with aligned pore structure for bone tissue engineering

S-W. Yook¹, H-E. Kim¹, Y-H. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

761

Design Rules for a Self-Healing Bone Cement

A. B. W. Brochu, W. M. Reichert;

Duke Univ., Durham, NC.

762

A Method for Reducing Variability in Bending Strength

O. Vesnovsky¹, H. W. Demian¹, T. O. Woods¹, T. L. D. Topoleski²;

¹FDA, Silver Spring, MD, ²UMBC, Catonsville, MD.

763

Electromechanical characterization of novel composite structures for spine implants

R. D. Perea, L. Friis;

Univ. of Kansas, Lawrence, KS.

764

Biomimetic structure of hydroxyapatite scaffolds by camphene-based freeze casting for bone tissue engineering

H-D. Jung¹, S-W. Yook¹, H-E. Kim¹, Y-H. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

765

Development of a New Synthetic Vertebral Cancellous Bone

J. P. Domann¹, A. Johnson², J. James², L. A. Friis¹;

¹Univ. of Kansas, Lawrence, KS, ²Pacific Res. Lab., Vashon, WA.

766

Fatigue and Wear Performance of a High Temperature Treated and Cross-Linked Polyethylene

E. W. Patten¹, S. A. Atwood¹, R. Tsay², J. Jhou², D. Sun³;

¹Univ. of California, Berkeley, Berkeley, CA, ²Natl. Yang-Ming Univ., Inst. of BioMed. Engineering, Taipai, TAIWAN, ³Taiwan Scientific Corp, Taipai, TAIWAN.

767

Wear Resistance of Polycarbonate Urethane Acetabular Cups as Compared to Cross-Linked Ultra High Molecular Weight Polyethylene

K. R. St. John, M. N. Gupta;

Univ. of Mississippi Med. Ctr., Jackson, MS.

768

Radiofrequency Neurotomy Does Not Cause Heating in Implant Materials

D. Fitch, K. Tanis, J. de Ana;

Smith & Nephew Inc., Memphis, TN.

769

Enhanced Surface Hardness of Zirconia Toughened Alumina (ZTA)

Y. LI¹, H-E. Kim², Y-H. Koh³;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ³Korea Univ., Seoul, KOREA, REPUBLIC OF.

770

Modulation of the Properties of p-Dioxanone Copolymeric Monofilament Sutures

B. P. Baum¹, D. R. Ingram¹, D. E. Linden¹, M. S. Taylor¹, K. J. L. Burg², S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

771

Self-primed Fabric in Self-reinforced UHMW-PE Composites: A Preliminary Study

S. J. Peniston, D. E. Carey, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

772

Observation of Slowed Reaction of Polyethylene Radicals in the Presence of Vitamin E

B. M. Walters;

Univ. of Memphis, Memphis, TN.

773

Alternative Sample Preparation Method for the Small Punch Test

W. P. Rodgers, III, J. A. Marini, S. James;

Colorado State Univ., Fort Collins, CO.

774

Cytotoxicity and bone mineralization properties of novel calcium phosphate-mullite composites

S. Nath, S. Kalmodia, B. Basu;

Indian Inst. of Technology Kanpur, Kanpur, INDIA.

775

Sintering, microstructure, mechanical properties and antimicrobial property of HAp-ZnO Biocomposites

B. Basu, Sr.¹, N. Saha, Sr.¹, E. Suvaci, Sr.², K. Keskinbora, Sr.²;

¹Indian Inst. of Technology Kanpur, Kanpur, INDIA, ²Anadolu Univ., Turkey, TURKEY.

776

In Vitro Properties of Lactide-rich PLGA Multifilament Braids

J. Thomas, O. Fabian, J. Hotter;

Covidien, North Haven, CT.

777

Suture Properties of Swellable, Absorbable Multifilament Braids

M. S. Taylor, D. R. Ingram, K. A. Carpenter, M. P. Jaeggli, B. P. Baum, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

778

Analysis of Mechanical Behavior of the Lumbar Spine Under High Impact Loading

D. Jamison, IV¹, M. Cannella¹, E. Pierce², S. Martin³, M. Marcolongo¹;

¹Drexel Univ., Philadelphia, PA, ²US SOCOM, Tampa, FL, ³Naval Surface Warfare Ctr., Panama City, FL.

779

Effects of a Nucleus Pulposus Implant on the Diurnal Biomechanics of the Human Intervertebral Disc_A Finite Element Analysis Study

C. J. Massey¹, C. C. van Donkelaar², M. Marcolongo¹;

¹Drexel Univ., Philadelphia, PA, ²Eindhoven Univ. of Technology, Eindhoven, NETHERLANDS.

780

Synthesis of Composite Bioactive Glass - Polymeric Microspheres for Controlled Drug Release

S. P. Cooper, A. B. Brennan;

Univ. of Florida, Gainesville, FL.

781

Nanostructure and Tensile Properties of UHMWPE after a Novel Post-Radiation Thermal Treatment

A. Bellare¹, D-C. Sun²;

¹Harvard Med. Sch., Boston, MA, ²Taiwan Scientific Corp., Taipei, TAIWAN.

782

The Effect of Uniaxial Compression and Stress Relaxation on the Tensile Properties of UHMWPE

A. Bellare, E. Abreu;

Harvard Med. Sch., Boston, MA.

783

⁷Be implantation as an alternative technique for wear measurement of UHMWPE - A Proof of Principle Study

M. A. Wimmer¹, Y. Dwivedi¹, M. P. Laurent¹, L. A. Gallardo¹, E. Rehm², U. Greife³;

¹Rush Univ. Med. Ctr., Chicago, IL, ²Argonne Natl. Lab., Argonne, IL, ³Colorado Sch. of Mines, Golden, CO.

Pluripotent Stem Cells in Regenerative Medicine

784

Co-axial Electrospun Polycaprolactone/Polyurethane Nanofibrous Scaffolds for Myocardial Tissue Engineering

J. M. Gluck¹, S. Heydarkhan-Hagvall¹, N. P. Ingle², R. J. Shemin¹, W. R. MacLellan¹;

¹Univ. of California, Los Angeles, Los Angeles, CA, ²North Carolina State Uninversity, Raleigh, NC.

785

Progenitor Motor Neurons for Transplantation after Spinal Cord Injury

D. A. McCreedy, S. E. Sakiyama-Elbert;

Washington Univ., St. Louis , MO.

Probing the Surface of Biology

786

Albumin Adsorption Behavior on Polystyrene and Glass Surfaces

E. Hillenmeyer, T. A. Horbett, W. Thomas, D. G. Castner;

Univ. of Washington, Seattle, WA.

787

Optimizing 3D molecular imaging with ToF-SIMS: A comparison between C60 single beam and Bin/C60 dual beam depth profiling

S. Muramoto, J. Brison, D. G. Castner;

Univ. of Washington, Seattle, WA.

788

AFM study of Mixed Carbohydrate/OEG Self-Assembled Monolayers

F. Tantakitti¹, F. Cheng¹, R. Egnatchik², D. N. Weiss³, D. M. Ratner¹;

¹Univ. of Washington, Seattle, WA, ²Vanderbilt Univ., Nashville, TN, ³Washington Technology Ctr., Seattle, WA.

789

Metabolic expression of methacrylate-derivatized sialic acids and surface modification on living cells

H. Matsuno, Y. Iwasaki;

Kansai Univ., Osaka, JAPAN.

Protein and Cells at Interfaces SIG

790

Time-Concentration Equivalence of Protein Adsorption Kinetics onto surfaces of Metallic Biomaterials

N. T. Jawrani, J. L. Gilbert;

Syracuse Univ., Syracuse, NY.

791

In vitro protein adsorption on binary mixed self assembled monoalyers studied by surface plasmon resonance

C-H. Shen, Z-Y. Chen, J-C. Lin;

Natl. Cheng Kung Univ., Tainan, TAIWAN.

Self-Assembly in Tissue Engineering

792

Bone Extracellular Matrix-Mimicking Self-Assembled Scaffold for Directing Osteogenic Differentiation of Human Mesenchymal Stem Cells without Soluble Factors

J. M. Anderson, J. B. Vines, A. Tambralli, H. Chen, A. Javed, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

793

Modulating Fibrin Matrices Using Knobx-PEG Conjugates

A. S. C. Soon, C. S. Lee, T. H. Barker;

Georgia Inst. of Technology, Atlanta, GA.

794

Microengineered Scaffolds to Guide Cell Assembly

C-C. Ho, G. Kumar, C. Co;

U of Cincinnati, Cincinnati, OH.

Smart PEEK Biomaterials: Engineering Tribological Surfaces and Bioactive Composites

795

Polyetheretherketone Multifilament and Monofilament Woven Tissue Engineering Scaffolds

S. L. Edwards¹, J. A. Werkmeister², J. A. M. Ramshaw², K. McLean², M. L. Jarman-Smith³;

¹CSIRO, Geelong, AUSTRALIA, ²CSIRO, Clayton, AUSTRALIA, ³Invibio Ltd., Thornton Cleveleys, UNITED KINGDOM.

796

Self-initiated surface graft polymerization from PEEK brings smart orthopaedic biomaterials

M. Kyomoto¹, T. Moro¹, K. Saiga¹, H. Onomoto², Y. Takatori¹, K. Ishihara¹;

¹The Univ. of Tokyo, Tokyo, JAPAN, ²Japan Med. Materials Corp., Osaka, JAPAN.

797

Effects of Annealing on Hydroxyapatite Whisker Reinforced Polyetherketoneketone Scaffolds

T. L. Conrad, G. L. Converse, R. K. Roeder;

Univ. of Notre Dame, Notre Dame, IN.

Stem Cell Microenvironments

798

Biomimetic Thymic Niche for Generating Functional, Antigen-Specific T cells from Stem Cells: Controlling Notch and T cell receptor Signaling in 3D Scaffolds

M. Kim, J. Lin, K. Roy;

The Univ. of Texas at Austin, Austin, TX.

799

Defined Substrates for Long-term Human Embryonic Stem Cell Culture

H. Nandivada, L. G. Villa-Diaz, G. D. Smith, J. Lahann;

Univ. of Michigan, Ann Arbor, MI.

800

Guided Differentiation of Mouse Embryonic Stem Cells with Protein-Immobilized Beads

L. R. Geuss¹, G. Zhang², L. J. Suggs¹;

¹Univ. of Texas at Austin, Austin, TX, ²The Univ. of Akron, Akron, OH.

801

Directed Assembly of Human Bone Marrow Stromal Cell-Laden Gels for Studying Paracrine Signaling

C. Tison, C. Simon, Jr.;

Natl. Inst. of Standards and Technology, Gaithersburg, MD.

802

The effects of microenvironment on the growth and differentiation of human pulpal-derived stem cells

L. C. Datko¹, M. Cupelli¹, M. Kennedy¹, S. Alapati², D. Dean¹;

¹Clemson Univ., Clemson, SC, ²Med. Univ. of South Carolina, Charleston, SC.

803

An Agent-based Model of Cortical Bone to Explore Cellular Interaction with their Microenvironment

L. Schutte;

Carnegie Mellon Univ., Pittsburgh, PA.

Stem Cell-Biomaterial Interactions

804

Isolation of Cord Blood-Derived Hematopoietic Stem Cells Using Macroporous Affinity Cryogel Matrix

A. Srivastava, D. A. Kumar;

Dept. of Biological Sci. and Bioengineering, Kanpur, INDIA.

805

Potential of N-Methacrylate Glycol Chitosan As A Matrix For Adipose-Derived Stem Cells Encapsulation

A. Sukarto;

Queen's Univ., Kingston, ON, CANADA.

806

Adipose-derived Stromal Cell Behaviors on Replicated Polymeric Lotus Leaf Structures

K. Cha¹, K-S. Park², D. Kim³, S-H. Lee², T. Kwon¹;

¹Pohang Univ. of Sci. and Technology (POSTECH), Pohang, KOREA, REPUBLIC OF, ²CHA Univ., Pochun, KOREA, REPUBLIC OF, ³Chung-Ang Univ., Seoul, KOREA, REPUBLIC OF.

807

Enhanced Osteogenesis of Mesenchymal Stem Cells in Calcium Phosphate/Collagen/Nanotube Scaffolds

L. Zhang¹, H. Fenniri²;

¹Rice Univ. & Univ. of California, Davis, Houston, TX, ²Natl. Inst. for Nanotechnology and Dept. of Chemistry, Univ. of Alberta, Edmonton, AB, CANADA.

808

Processed Lipoaspirate (PLA) Cells Seeded on 3-Dimensional Calcium Phosphate-Collagen-Chitosan-Based Spongy Scaffolds for Potential Bone Tissue Engineering Application

V. V. Silva¹, M. S. Giusta², A. M. Goes²;

¹Univ.e Federal do ABC, Santo André, BRAZIL, ²Univ.e Federal de Minas Gerais, Belo Horizonte, BRAZIL.

Stimuli-responsive Scaffolds for Tissue Engineering: New Developments

809

Influence of Polymer Scaffold Architecture on the Shear Stress Distribution and Dynamic Culture of Preosteoblastic Cells

S. B. VanGordon, R. S. Voronov, T. B. Blue, R. L. Shambaugh, V. I. Sikavitsas, D. V. Papavassiliou;

Univ. of Oklahoma, Norman, OK.

810

Enhanced Cartilaginous Tissue Formation with a Cell aggregate-Fibrin-Polymer scaffold Complex

Y. Jung¹, S-H. Kim¹, Y. Kim², S. Kim¹;

¹Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ²Gwangju Inst. of Sci. and Technology, Gwangju, KOREA, REPUBLIC OF.

811

Mechanostimulated Wharton’s Jelly Stem Cells Seeded into Human Umbilical Veins for Tendon Tissue Engineering

W. Yates, V. I. Sikavitsas;

Univ. of Oklahoma, Norman, OK.

812

Pliable Semi-Crystalline Polymer Scaffolds with Controlled Parallel-Channel Architecture for Nerve Repair

M. Ebara, T. Muroya, T. Aoyagi;

Natl. Inst. for Materials Sci., Ibaraki, JAPAN.

813

Neurite Outgrowth is Additively Increased by Co-Stimulation with Physiologic Electric Fields and Schwann Cells

A. N. Eldridge, D. M. Thompson;

Rensselaer Polytechnic Inst. & Ctr. for Biotechnology and Interdisciplinary Studies, Troy, NY.

Surface Characterization and Modification SIG

814

Grafting sodium styrene sulfonate onto titanium surfaces for improved biocompatibility

G. Zorn, D. G. Castner;

Univ. of Washington, Seattle, WA.

815

Degradation Mechanism of Human Explanted Heavy Weight Polypropylene Hernia Meshes

D. N. Grant, S. L. Bachman, B. Ramshaw, D. A. Grant, S. A. Grant;

Univ. of Missouri, Columbia, MO.

816

A Study on Surface Topology of Polydioxanone after In Vitro and In Vivo Degradation

C-Y. Chiang¹, M. Deng², O. Rathore²;

¹Johnson and Johnson Consumer Products Company, Skillman, NJ, ²Ethicon, Inc., a Johnson & Johnson Company, Somerville, NJ.

817

Characterization of Functionalized Gold Nanoparticle and their Interactions with Model Peptides and Protein G

S. D. Techane, L. J. Gamble, D. G. Castner;

Univ. of Washington, Seattle, WA.

818

Surface Characterization of the Vertebral Body for In-Vitro Wear Testing of Nucleus Replacement Device

V. Singh, J. P. Shorez, P. E. Paré;

Medtronic, Inc., Memphis, TN.

Surface Modification and the Biological Response

819

Engineering Notch Signaling Activation for Generating Human Embryonic Stem Cell-Derived Cardiomyocytes

J. C. Tung, C. E. Murry, B. D. Ratner, C. M. Giachelli;

Univ. of Washington, Seattle, WA.

820

Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific Adhesion

N. Artzi¹, T. Shazly¹, A. Baker¹, A. B. Ramos², E. Edelman¹;

¹Massachusetts Inst. of Technology, Cambridge, MA, ²Univ.t Ramon Llull, Barcelona, SPAIN.

821

Bioactive Hybrid Nanomatrix Composed of Electrospun Polycaprolactone and Self-Assembled Peptide Amphiphiles

B. A. Blakeney, A. Tambralli, J. M. Anderson, A. Andukuri, D. R. Dean, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

822

Poly(ethylene glycol)-grafted Poly(propylene fumarate) Networks for Regulating Surface Physicochemical Characteristics and MC3T3 Cell Behavior

S. Wang, L. Cai;

The Univ. of Tennessee, Knoxville, TN.

823

Towards Thromboresistive Artificial Lungs: The Role of Copper-Doped Nitric Oxide-Generating Silicone for Blood-Contacting Surfaces

K. A. Amoako, R. H. Bartlett, K. E. Cook;

Univ. of Michigan, Ann Arbor, MI.

824

Enhanced Cellular Adhesion and Controlled Gene Delivery on Glycol-Chitosan-Based Polyelectrolyte Multilayer Films

C. Holmes, M. Tabrizian;

McGill Universiy, Montreal, QC, CANADA.

825

Improvement of biocompatibility of biomaterials by dopamine treatment

H-W. Chien, W-T. Chen, W-B. Tsai;

Natl. Taiwan Univ., Taipei, TAIWAN.

826

Decreased lung carcinoma cell density on select polymer nanometer surface features for lung replacement therapies

L. Zhang, T. Webster;

Brown Univ., Providence, RI.

827

Poly(ethylene glycol) nanogel coated surfaces display ultralow protein adsorption: Quantification by single molecule detection

C. Donahoe, L. Tessler, Y-S. Jun, R. Mitra, D. Elbert;

Washington Univ. in St. Louis, St. Louis, MO.

828

Neuronal Pathfinding on Dot Gradients of Mixed Permissive and Inhibitory Protein Cues

T. W. Hsiao, P. A. Tresco, V. Hlady;

Univ. of Utah, Salt Lake City, UT.

829

The Ca2+-Dependent but Not the Canonical Wnt Pathway Enhances Osteoblast Maturation on TitaniumMicrostructured Surfaces

R. Olivares-Navarrete¹, D. Hutton¹, G. Dunn¹, S. Hyzy¹, M. Dard², A. Molenberg², B. D. Boyan¹, Z. Schwartz¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Inst. Straumann, Basel, SWITZERLAND.

830

Survival and apoptosis in vitro of osteoblastic cells in contact with synthetic bone grafts

J. Kim¹, G. Berger², R. Gildenhaar², I. Shapiro³, P. Ducheyne¹, C. Knabe⁴;

¹Univ. of Pennsylvania, Philadelphia, PA, ²Federal Inst. for Materials Res. and Testing, Berlin, GERMANY, ³Thomas Jefferson Univ., Philadelphia, PA, ⁴Charite Univ. Med. Ctr., Berlin, GERMANY.

831

Strong Resistance to Protein Adsorption by (Tridecafluoro-1,1,2,2-tetrahydrooctyl)triethoxysilane Nanofilm

C. Alluri¹, H. Ji², P. Sit¹;

¹Louisiana Tech Univ., Ruston, LA, ²Drexel Univ., Philadelphia, PA.

832

Microfabrication and Patterning of Protein Arrays

B. R. Whatley¹, B. Damon², X. Wen¹;

¹Clemson Univ., Charleston, SC, ²Med. Univ. of South Carolina, Charleston, SC.

833

Development of maskless photolithography method with an LCD-projector for fabrication of micropatterned surfaces

K. Itoga, J. Kobayashi, M. Yamato, T. Okano;

Tokyo Women's Med. Univ., Tokyo, JAPAN.

834

Implant Coatings based on Enzymes improve Osteogenic Responses in vivo

J. van den Beucken, C. Schouten, L. de Jonge, E. Bronckhorst, G. Meijer, J. Jansen;

Radboud Univ. Nijmegen Med. Ctr., Nijmegen, NETHERLANDS.

835

Effect of Microtopography and Surface Modulus on Pheochromocytoma (PC12) Cell Neurite Outgrowth.

S. H. Jariwala, J. M. Hasenwinkel;

Syracuse Univ., Syracuse, NY.

836

Anti-microbial coatings for urological applications

E. E. M. van den Bosch, P. Wyman, L. Bremer, O. J. Gelling;

DSM BioMed. Materials, Urmond, NETHERLANDS.

837

Blood Compatibility of Poly(ethylene glycol)-methacrylate /Acrylic acid Copolymer Coated Surfaces

C-W. Chang¹, W-H. Kuo¹, M-J. Wang¹, W-B. Tsai²;

¹Natl. TaiwanUniv. of Sci. and Technology, Taipei, TAIWAN, ²Natl. Taiwan Univ., Taipei, TAIWAN.

838

The Fabrication of Multifaceted Patterned Surfaces Using Laser Scanning Lithography

J. H. Slater, J. S. Miller, S. S. Yu, J. L. West;

Rice Univ., Houston, TX.

839

Matrix Hydrophobicity affects templated mineralization of polymeric hydrogel scaffold materials

A. Phadke, C. Zhang, S. Varghese;

Univ. of California, San Diego, La Jolla, CA.

840

PEGylated-Peptide Coatings for the Inhibition of Pathogenic Biofilms on Titanium Metal

X. Khoo¹, G. O'Toole, Jr.², D. Kenan³, M. Grinstaff¹;

¹Boston Univ., Boston, MA, ²Dartmouth Med. Sch., Hanover, NH, ³Duke Univ., Durham, NC.

841

Designing Nanostructured Surfaces for Enhanced Biocompatibility

F. Namavar¹, R. F. Sabirianov², A. Rubinstein², J. D. Jackson¹, J. Sharp¹, H. Haider¹, K. L. Garvin¹;

¹Univ. of Nebraska Med. Ctr., Omaha, NE, ²Univ. of Nebraska, Omaha, NE.

842

Decreased Infection and Epithelial Cell Attachment to Lubricin Coated Intraocular Lenses

G. E. Aninwene, II, E. Taylor, Sr., T. J. Webster, G. D. Jay;

Brown Univ., Providence, RI.

843

In Vitro and In Vivo Characterizations of Induction Plasma Sprayed Hydroxyapatite coating on Ti for Load Bearing Implants

M. Roy, A. Bandyopadhyay, S. Bose;

Washington State Univ., Pullman, WA.

844

Encapsulation of b-FGF in Silica Xerogel/Chitosan Hybrid Coating for Controlled Release

S-H. Jun¹, E-J. Lee¹, H-E. Kim¹, J-H. Jang²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Inha Univ., Seoul, KOREA, REPUBLIC OF.

845

Characterization and Modification of Surface Integrity by Laser Peening Biodegradable Magnesium-Calcium Alloys

Y. Guo, M. Sealy;

The Univ. of Alabama, Tuscaloosa, AL.

846

Size-sensitive protein adsorption on silicon surfaces grafted with poly (N-isopropylacrylamide)

H. Chen, Q. Yu, Y. Zhang, Z. Wu, H. Huang, C. Cheng;

State Key Lab. of Advanced Technology for Materials Synthesis and Processing, Wuhan Univ. of Technology, Wuhan, CHINA.

847

Bioactivity and corrosion resistance of novel coatings containig strontium by anodic oxidation

K-C. Kung, T-M. Lee, T-S. Lui;

Natl. Cheng Kung Univ., Tainan, TAIWAN.

848

Blood Compatibility on Poly(acrylic acid- sulfobetaine methacrylate) Polyelectrolyte Multilayer Modified Surfaces

W-H. Kuo¹, M-J. Wang¹, W-B. Tsai², C. Lee¹;

¹Natl. Taiwan Univ. of Sci. and Technology, Taipei, TAIWAN, ²Natl. Taiwan Univ., Taipei, TAIWAN.

849

Radiopaque Microspheres containing Acrolein for Protein Attachment to improve Cell Adhesion and Blood Coagulation

K. Saralidze, M. L. W. Knetsch, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.

850

Characteristics and Biological Responses of Novel Coatings Containing Strontium by Micro-Arc Oxidation

T-M. Lee¹, K-C. Kung², T-S. Lui²;

¹Inst. of Oral Med., Natl. Cheng Kung Univ., Tainan, TAIWAN, ²Inst. of Materials Sci. and Engineering, Natl. Cheng Kung Univ., Tainan, TAIWAN.

851

Anodized Micro and Nanoporous Titania Layer for Controlled Drug Release

C-M. Han¹, E-J. Lee¹, H-E. Kim¹, J-H. Jang²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Inha Univ., Incheon, KOREA, REPUBLIC OF.

852

Microstructural Analysis on Biological Disintegration of Hydroxyapatite

D. Seo, Y. Ko, J. Lee;

Chosun Univ., Gwangju, KOREA, REPUBLIC OF.

853

Liposome mediated uptake of macrophages using surface modification

D. Davalian, H. MA, M. Trollsas, S. Hossainy;

Abbott vascular, Santa Clara, CA.

854

Biodegradable Polymers for Stealth Neural Probes

D. Lewitus¹, K. L. Smith², W. Shain², J. Kohn¹;

¹Rutegrs Univ., Piscataway, NJ, ²Wadsworth Ctr., Albany, NY.

855

Cellular Behavior on Anodized vs. Non-anodized Titanium Under Cathodic Polarization

M. Haeri, J. L. Gilbert;

Syracuse Univ., Syracuse, NY.

856

A Study of the Effect of Sample Orientation on Platelet Adhesion Using Negative Charge Density Gradients

L. E. Corum;

Univ. of Utah, Salt Lake city, UT.

857

Bottom-up Modification of Biomaterial Surface for Control of Cell Adhesion and Alignment

S-Y. Choh, C. Wang;

Univ. of Minnesota, Minneapolis, MN.

858

Micropatterning of Hydrogels by Visible Light Irradiation with Maskless Photolithography Device

J. Kobayashi, K. Itoga, M. Yamato, T. Okano;

Tokyo Women's Med. Univ., Tokyo, JAPAN.

859

Bio-functionalization of Inorganic Surfaces through Inorganic Binding Peptides

D. Khatayevich¹, M. Gungormus¹, C. So¹, S. Cetinel¹, C. Tamerler², M. Sarikaya¹;

¹GEMSEC, Univ. of Washington, Seattle, WA, ²Dept. of Molecular Biology and Genetics, Istanbul Technical Univ., Istanbul, TURKEY.

860

Evaluation of Chitosan Coated on Titanium to Deliver Vascular Endothelial Growth Factor-121 and Enhance Saos-2 Cell Mineralization In Vitro

M. R. Leedy, J. D. Bumgardner, W. O. Haggard;

Univ. of Memphis, Memphis , TN.

861

Removing Endotoxin from Metallic Biomaterials with Compressed Carbon Dioxide-Based Mixtures

M. A. Matthews, P. J. Tarafa, J. Zhang, S. Panvelker, E. Williams;

Univ. of South Carolina, Columbia, SC.

862

Heparin Immobilization onto Plasma Modified Polyethylene Terephthalate to Improve Blood Compatibility

S. Eftekhari;

Ryerson Univ., Toronto, ON, CANADA.

863

Osteoblast-Fibroblast Co-Culture on Anodized Titanium with Electrical Stimulation for Orthopedic Applications

C. D. Hartman, B. Ercan, T. J. Webster;

Brown Univ., Providence, RI.

864

Enhancement of cell adhesion and proliferation on polyetheretherketone by using plasma surface modification

K. Yeung, S. C. Lui, P. K. Chu, K. Luk, K. Cheung;

The Univ. of Hong Kong, Hong Kong, HONG KONG.

865

Sol-gel multilayer hydroxyapatite coating for dental implants osseointegration

R. Chiesa¹, C. Della Valle¹, G. Moretti¹, L. De Nardo¹, G. Candiani¹, I. Alfieri², A. Cigada¹, A. Montenero³;

¹Politecnico di Milano, Milan, ITALY, ²Università di Parma, Parma, ITALY, ³Univ.' di Parma, Parma, ITALY.

866

Comparison of poly(ethylene glycol) and sulfobetaine chemical moieties for the suppression of biomaterial fouling

D. E. Heath, S. L. Cooper;

The Ohio State Univ., Columbus, OH.

867

E-beam Deposited Calcium Phosphate Coating Layer as an Active Surface to Induce Bioactive Molecule-apatite Composite

C. Chen¹, I-S. Lee¹, S-M. Zhang², H-C. Yang³, S-H. Choi⁴, S-M. Chung⁵;

¹Atomic-scale Surface Sci. Res. Ctr., Yonsei Univ., Seoul, KOREA, REPUBLIC OF, ²Advanced Biomaterials and Tissue Engineering Ctr., HUST, Wuhan, CHINA, ³Dept. of Dental Biomaterials Sci., Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ⁴Dept. of Periodontology, Yonsei Univ., Seoul, KOREA, REPUBLIC OF, ⁵Implatium Implant Inst., Seoul, KOREA, REPUBLIC OF.

868

Reduction of the corrosion rate of biodegradable metallic materials by Al2O3 PIII surface treatment

H. M. Wong¹, K. Yeung¹, K. O. Lam¹, P. K. Chu², K. Luk¹, K. Cheung¹;

¹The Univ. of Hong Kong, Hong Kong, HONG KONG, ²City Univ. of Hong Kong, Hong Kong, HONG KONG.

869

Probing Complex Cell Behavior on Individual Polystyrene Nanofibers

J. A. Zimberlin, M. C. Weiger, M. T. Cicerone;

Natl. Inst. of Standards and Technology, Gaithersburg, MD.

870

Compositionally Graded Hydroxyapatite/Tricalcium Phosphate Coating on Ti using Laser and Induction Plasma Spray for Load Bearing Implants

M. Roy, A. Bandyopadhyay, S. Bose;

Washington State Univ., Pullman, WA.

871

Selective Protein Adsorption Influenced by Exposure of Electrical Charges Along Grain Boundaries on Metals

D. Marton¹, A. Choubey², E. A. Sprague¹;

¹UTHSCSA, San Antonio, TX, ²Palmaz Scientific, Inc., Fremont, CA.

872

The effects of plasma ion immersion implantation on the tribological performance of a medical grade Ti alloy

G. Chiu¹, W. Tsai², C. Ai², R. Tsay¹;

¹Inst. of BioMed. Engineering Natl. Yang-Ming Univ., Taipei, TAIWAN, ²Physics Div., Inst. of Nuclear Energy Res., Taoyuan, TAIWAN.

873

Novel Controllable-Wettability Gradients on Polypropylene Surfaces for Cell Screening

D. Mangindaan, S-L. Wang, M-J. Wang;

Natl. Taiwan Univ. of Sci. and Technology, Taipei, TAIWAN.

874

Effect of surface treatments on localized corrosion behavior of Nitinol alloys

W. Haider, N. Munroe, V. Tek, P. Gill, C. Pulletikurthi, S. Pandya;

Florida Intl. Univ., Miami, FL.

875

Nitric Oxide-releasing, but not Nitric Oxide-generating, Polymer Coating Preserves Platelet Count and Function in Extracorporeal Circulations

T. C. Major, D. O. Brant, M. M. Reynolds, R. H. Bartlett, M. E. Meyerhoff, H. Handa, G. Annich;

Univ. of Michigan, Ann Arbor, MI.

876

Combined Antimicrobial and Antithrombogenic Properties of Betaine Polymers on Carbothane® Substrates

Z. Zhang, C. Huval, M. Bouchard, J. Li, V. E. Wagner, C. R. Loose;

Semprus BioSci., Cambridge, MA.

877

A Review on the Technologies for Micro-Patterning Self-Assembled Monolayers to Understand Interactions of Biomaterials with Surfaces

R. Shadnam;

KPMG, Vancouver, BC, CANADA.

878

Hydrophobic Elastomeric Fiber Mats for Soft Tissue Engineering and Wound Care

G. Lim¹, M. S. Casiano-Maldonado², X. Li¹, C. Wesdemiotis¹, D. H. Reneker¹, J. E. Puskas¹;

¹Univ. of Akron, Akron, OH, ²Dept. of Chemistry, Univ. of Akron, Akron, OH.

879

The Relationship between Fibronectin Conformation and Osteoblast Cell Morphology On Iodine Containing Tyrosine-derived Polycarbonate Blends

K. A. Aamer¹, K. Genson², J. Kohn³, M. L. Becker⁴;

¹Natl. Inst. of Standards and Technology, Gaithersburg, MD, ²Purdue Univ., Lafayette, IN, ³Rutgers Univ., Piscataway, NJ, ⁴Univ. of Akron, Akron, OH.

Surface Modification of Three Dimensional Scaffolds for Tissue Engineering Applications

880

Calcium Phosphate Coating of EBM Manufactured Three-Dimensional Titanium Scaffolds via Alkali Heat Treatment

N. J. Castro, M. Cooke;

Univ. of Texas at El Paso, El Paso, TX.

881

2.5D Constructs for Surface Evaluation of 3D Scaffolds in Tissue Engineering

J. E. Marszalek¹, A. Karim¹, A. G. Basnakian², C. Simon³;

¹Univ. of Akron, Akron, OH, ²2Univ. of Arkansas for Med. Sci., Little Rock, AR, ³Polymers Div., NIST, Gaithersburg, MD.

882

Plasma Surface Modification of Electrospun Poly(ε-Caprolactone) Nanofibers for Potential Tissue Engineering Scaffold Applications

J. E. Jones, H. Li, Q. Yu;

Univ. of Missouri, Columbia, MO.

883

A Novel Single-species Self-assembly Process to Fabricate Collagen-like Nano-fibrous Poly(L-lactic acid) Scaffolds

X. Liu, J. Wang, P. X. Ma;

Univ. of Michigan, Ann Arbor, MI.

Surface Optimization to Maximize Biosensor Performance

884

Protein Recognitive Hydrogel Systems for Biosensor Applications

D. Kryscio, N. Peppas;

Univ. of Texas at Austin, Austin, TX.

885

Absorbance-based pH Sensor Utilizing a Sol-Gel Matrix Suffers From Leaching Based Upon Form of Dye

M. Nielsen¹, Y. Qi², M. C. Frost¹;

¹Michigan Technological Univ., Houghton, MI, ²Univ. of Notre Dame, Notre Dame, IN.

886

Optimizing Carbohydrate Microarray Fabrication

F. Cheng, J. Shang, D. M. Ratner;

Univ. of Washington, Seattle, WA.

887

A Simple and Versatile Method to Fabricate Glycan Arrays

J. Shang, F. Cheng, D. M. Ratner;

Univ. of Washington, Seattle, WA.

888

Use of CD Spectroscopy to Assess the Biocompatibility of Silica-based Materials

D. K. Eggers, G. R. Abel, Jr., P. J. Calabretta, M. C. Chancellor, C. Torres;

San Jose State Univ., San Jose, CA.

Targeted Drug Delivery / Polymer Conjugates

889

Cell-based OPG gene modification on aseptic knee implant loosening in a mouse model

S-Y. Yang¹, L. Zhang², A. Chong¹, H. Yu¹, P. H. Wooley¹;

¹Via Christi Regional Med. Ctr., Wichita, KS, ²Shandong Univ. Sch. of Med., Jinan, CHINA.

890

Novel Anti-Oxydative Stress Nanoparticle for Ischemia Reperfusion Injury

Y. Nagasaki;

Univ. of Tsukuba, Tsukuba, Ibaraki, JAPAN.

891

Angiogenesis Imaging of Tumor Xenografts by alpha v beta 3 - Targeted, Dual-Modality Micellar Nanoprobes

C. W. Kessinger, C. Khemtong, O. Togao, M. Takahashi, B. D. Sumer, J. Gao;

UT Southwestern Med. Ctr., Dallas, TX.

892

Targeting of Gram-Positive Pathogens to Phagocytes by Multivalent Artificial Opsonins

K. N. Katzenmeyer, J. D. Bryers;

Univ. of Washington, Seattle, WA.

893

Tunable Release of Doxorubicin in Cancer Tumors Using Polymeric Micelles

A. G. Ponta, Y. Bae;

Dept. of Pharmaceutical Sci., Coll. of Pharmacy, Univeristy of Kentucky, Lexington, KY.

894

Amphiphilic Hyauronic Acid Derivates as a Potential Carrier for Protein Drug

A. Kang;

kyung hee Univ., youngin, KOREA, REPUBLIC OF.

895

Mucoadhesive Alginate/Poly-L-Lysine/Thiolated Alginate Microcapsules for oral delivery of Lactobacillus salivarius 29

M. A. Islam;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

896

Self-Assembly of Hyaluronate-Cucurbituril Conjugate for Controlled Drug Delivery Applications

J. Yang, K. Park, H. Jung, K. Kim, S. Hahn;

POSTECH, Pohang, KOREA, REPUBLIC OF.

897

Target Specific and Long-Acting Delivery of Biopharmaceuticals Using Hyaluronic Acid Derivatives

S. Hahn, E. Oh, K. Park, K. Kim, J-A. Yang;

Pohang Univ. of Sci. and Technology (POSTECH), Pohang, KOREA, REPUBLIC OF.

898

Anti-inflammatory and anti-oxidant activity of novel biodegradable copolyoxalate nanoparticles

D. Lee, H. Park, H. Seo, S. Kim, Y. Lee;

Chonbuk Natl. Univ., Jeonju, Chonbuk, KOREA, REPUBLIC OF.

899

Controlled Delivery of Epidermal Growth Factor for Neural Stem Cell Stimulation after Stroke

Y. Wang;

Univ. of Toronto, Toronto, ON, CANADA.

900

Synthesis of High Transition Temperature Hyperbranched poly(N-Isopropyl Acrylamide)

K. Chang, L. J. Taite;

Georgia Inst. of Technology, Atlanta, GA.

901

Effect of pressure treatment on lipoplex formation and their transfection

T. Kimura¹, H. Konno¹, A. Sano¹, T. Fujisato², A. Kishida¹;

¹Tokyo Med. and Dental Univ., Tokyo, JAPAN, ²Osaka Inst. of Technology, Osaka, JAPAN.

902

Preparation of size-controlled amphiphilic poly(amino acid) nanoparticles for vaccine delivery and adjuvant

T. Akagi¹, H. Kim¹, T. Uto², M. Baba², M. Akashi¹;

¹Graduate Sch. of Engineering, Osaka Univ., Suita, JAPAN, ²Graduate Sch. of Med. and Dental Sci., Kagoshima Univ., Kagoshima, JAPAN.

903

Therapeutic Response in a Xenograft Mice Model by Folated PEG-PCL-PEI/TAM67 complexes

R. B. Arote, S-K. Hwang, H-L. Jiang, Y-K. Kim, M-H. Cho, C-S. Cho;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

904

Polypyrrole-coated nanostructured electrodes to improve impedance and controlled local anti-inflammatory drug delivery.

L. Leprince;

Université catholique de Louvain, Louvain-la-Neuve, BELGIUM.

905

Tumor-targeting, pH-responsive and stable unimolecular micelles as drug nanocarriers for targeted cancer therapy

S. Gong;

UW-Milwaukee, Milwaukee, WI.

906

Multifunctional, Polymeric Worm-like Vesicles Based on Triblock Copolymers for Tumor-targeted Imaging and Drug Delivery

S. Gong;

UW-Milwaukee, Milwaukee, WI.

907

Novel Poly(ethylene glycol) Dendrimers for Drug Delivery Applications

K. Seo, J. E. Puskas, M. Casiano, C. Wesdemiotis;

The Univ. of Akron, Akron, OH.

908

Polyoxalate nanoparticles as new biodegradable and non-inflammatory drug delivery systems

D. Lee, S. Kim, K. Seong, E. Lee, O. Kim;

Chonbuk Natl. Univ., Jeonju, Chonbuk, KOREA, REPUBLIC OF.

909

A Facile Method to Construct pH-Responsive Drug Delivery System Using Chitosan-Based Polymers

L-Q. Wang, Q. Cai, H. Jiang, K. Tu, K. Zhu;

Inst. of Polymer Sci., Hangzhou, CHINA.

910

Grafted Block Copolymer Nano-Assembly (GNA) Drug Carriers

H. Lee, Y. Bae;

Univ. of Kentucky, Lexington, KY.

911

Enzymatically-degradable, sulfated poly(N-isopropylacrylamide) nanoparticles for drug delivery applications

R. L. Bartlett, II, M. R. Medow, B. L. Seal;

Purdue Univ., 206 S. Martin Jischke Drive, IN.

912

Cell type-dependent uptake of PEG-ylated nanoparticles

K. K. Tran, A. Sheih, H. Dinh, H. Shen;

Univ. of Washington, Seattle, WA.

913

Corticosteroids Functionalized Poly(N-vinyl pyrrolidone) as a pH-sensitive Drug Delivery System at Neural Interface

Y. Cao, W. He;

Univ. of Tennessee, knoxville, TN.

914

Amino Acid Based Polyesteramides And Polyesterurethanes : Cell Responsive Matrices For Drug Delivery

A. A. Dias;

DSM BioMed., Geleen, NETHERLANDS.

915

Elastomer Impregnated with silver ions using a unique mixture of solvents imparts unique silver ion elution characteristics

B. Luchsinger, T. Meyer;

Bacterin Intl., Belgrade, MT.

916

Biodegradable Nanoparticles for Receptor-Mediated Oral Protein Delivery

E. Brewer, A. Lowman;

Drexel Univ., Philadelphia, PA.

917

Neuron-specific polymeric micelle nanotherapeutics for CNS regeneration

J. Lee, J. Zhang, K. Webb;

Clemson Univ., Clemson, SC.

918

Synthesis, Characterization and Lymphatic Trafficking of Polymeric Nanoparticles

K. V. Zubris¹, O. Khullar², J. V. Frangioni³, Y. L. Colson², M. W. Grinstaff¹;

¹Boston Univ., Boston, MA, ²Brigham and Women's Hosp., Boston, MA, ³Beth Israel Deaconess Med. Ctr., Boston, MA.

919

Femtosecond laser photoporation of nanoparticles into vital cells

P. Soman, W. Zhang, S. Chen;

Univ. of Texas, Austin, Austin, TX.

920

Targeted Nitric Oxide Donors for Enhanced Drug Delivery and Treatment of Glioblastoma Multiforme

S. Safdar, L. J. Taite;

Georgia Inst. of Technology, Atlanta, GA.

921

Convection-enhanced Delivery of Cancer-targeting Biomacromolecules

M. R. Caplan¹, J. M. Stukel¹, A. Gizzi², C. Cherubini², S. Filippi²;

¹Arizona State Univ., Tempe, AZ, ²Univ. Campus Bio-Med. di Roma, Roma, ITALY.

922

Quantum dot-labeled dendrimer-triglycine-EGF nanoparticles for targeted imaging and nucleic acid delivery

Q. Yuan, E. Lee, W. Yeudall, H. Yang;

Virginia Commonwealth Univ., Richmond, VA.

Tissue Engineered Disease Models

923

An Electro-Mechanical Bioreactor for Engineering Diseased Cardiac Tissue Models

R. A. Lasher, M. K. Parikh, F. B. Sachse, R. W. Hitchcock;

Univ. of Utah, Salt Lake City, UT.

924

Towards Cell-Mediated Regeneration of Elastic Matrix Structures in De-Elasticized Blood Vessels

C. E. Gacchina, A. Ramamurthi;

Clemson Univ., Charleston, SC.

925

Macrophages Systemic Recruitment Induced by Continuously Infused UHMWPE Particles in Nude Mice

P-G. Ren, A. Irani, Z. Huang, T. Ma, S. Biswal, R. L. Smith, S. B. Goodman;

Stanford Univ., Stanford, CA.

926

Toward In Situ Tissue Engineering of Elastic Matrix Structures in Doxycycline-Stabilized Vascular Aneurysms

E. L. Ongstad, A. Ramamurthi;

Clemson Univ., Charleston, SC.

927

Host Response to Biomaterial Scaffolds Implanted into Osteochondral Defects in Rabbit Knees with Rheumatoid Arthritis

J. Park, R. A. Patel, C. L. Oliver, A. S. P. Lin, L. O’Farrell, R. Guldberg, J. E. Babensee;

Georgia Inst. of Technology, Atlanta, GA.

928

In vitro culture models elucidate a role for planar cell polarity signaling in endothelial cell migration

A. P. McGuigan¹, Z. Jiang¹, G. Rizvi¹, E. Vladar², D. Antic², J. Axelrod²;

¹Univ. of Toronto, Toronto, ON, CANADA, ²Stanford Univ., Palo Alto, CA.

929

Histological and mCT Analysis of Biomaterial Scaffolds Implanted into Osteochondral Defects in Rabbit Knees with Rheumatoid Arthritis

R. A. Patel, J. Park, C. L. Oliver, A. Lin, L. O'Farrell, R. E. Guldberg, J. Babensee;

Georgia Inst. of Technology, Atlanta, GA.

930

Functional repair of skeletal muscle defects using tissue engineered skeletal muscle created from myoblasts seeded on bladder acellular matrix and preconditioned in a bioreactor

M. Machingal¹, B. Corona², V. Kesireddy², K. Andersson², M. Herco², S. Vishwajit², B. Bishwokarma², W. Zhao², J. J. Yoo², G. J. Christ²;

¹VT-WFU Sch. of BioMed. Engineering and Sci., Winston Salem, NC, ²Wake Forest Inst. for Regenerative Med., Winston Salem, NC.

Tissue Engineering SIG

931

Biodegradation of Polyurethane Tissue Engineering Scaffolds

A. E. Hafeman, K. J. Zienkiewicz, L. M. Nanney, J. M. Davidson, S. A. Guelcher;

Vanderbilt Univ., Nashville, TN.

932

Design and Development of a Highly Macroporous, Protein Coated Silicone Scaffold as a Bioartificial Pancreas forType 1 Diabetes

E. Pedraza, A-C. Brady, A. Pileggi, C. L. Stabler;

Univ. of Miami, Miami, FL.

933

Development of a High Throughput Screen to Create an Optimized Biomaterial for Peripheral Nerve Injury

A. N. Eldridge, C. M. Dumont, G. Singh, V. D. Alphonse, P. Karande, D. Thompson;

Rensselaer Polytechnic Inst. & Ctr. for Biotechnology and Interdisciplinary Studies, Troy, NY.

934

Integration of A Photo-induced pH-Jump Reaction into pH-responsive Hydrogels for Local Gel Shrinking

P. Techawanitchai¹, M. Ebara², T. Aoyagi²;

¹Univ. of Tsukuba, Ibaraki, JAPAN, ²Natl. Inst. for Materials Sci., Ibaraki, JAPAN.

935

Rat Model for Traumatic Volumetric Muscle Loss: A Platform for Testing Engineered Skeletal Muscle

T. J. Walters, R. J. Christy, X. Wu;

U.S. Army Inst. of Surgical Res., Fort Sam Houston, TX.

936

Prediction of Collagen and Glycosaminoglycan Content by Acoustic Microscopy

J. R. Popp¹, C. M. Flannery¹, T. L. Oreskovic¹, J. B. Recknor¹, K. S. Anseth², T. P. Quinn¹;

¹Natl. Inst. of Standards and Technology, Boulder, CO, ²Univ. of Colorado, Boulder, CO.

937

Effect of a Young’s Modulus Gradient on Neurite Extension in PC12 Cells

P. S. Varde, J. M. Hasenwinkel;

Syracuse Univ., Syracuse, NY.

938

Response of Osteoblast Precursor Cells to Cyclic Compressive and Tensile Strain on a Titanium Substrate

A. P. Noblett, W. O. Haggard, J. D. Bumgardner;

Univ. of Memphis, Memphis , TN.

939

The electroactivity and stability of conductive PPy/HE/PLLA membranes

Z. Zhang, L. Zhang;

Hôpital Saint-François d'Assise, Québec, QC, CANADA.

Transcatheter Heart Valve Prostheses and Other Biomaterial Innovations for Treating Heart Valve Disease

940

Minimally Invasive Implantation of Tissue Engineered Living Autologous Self-Expandable Heart Valves in an Animal Model

B. Weber¹, D. Schmidt¹, R. Stenger¹, B. Odermatt², G. Zund¹, S. P. Hoerstrup¹;

¹Clinic for Cardiovascular Surgery, Dept. of Surgical Res., Univ. Hosp., Zurich, SWITZERLAND, ²Inst. of Clinical Pathology, Univ. Hosp., Zurich, SWITZERLAND.

941

Prevention of Bioprosthesic Calcification with Triglycidylamine (TGA) and Ethanol (EtOH) Pretreatment

J. M. Connolly¹, M. A. Bakay¹, H. S. Kruth², P. E. Ashworth³, S. J. Stachelek¹, R. W. Bianco⁴, F. J. Schoen⁵, R. Gorman⁶, J. Gorman, III⁶, R. J. Levy¹;

¹The Children's Hosp. of Philadelphia, Philadelphia, PA, ²NIH, Bethesda, MD, ³St Jude Med., Inc., St. Paul, MN, ⁴Univ. of Minnesota, Minneapolis, MN, ⁵Brigham and Women’s Hosp. and Harvard Med. Sch., Boston, MA, ⁶Univ. of Pennsylvania Sch. of Med., Philadelphia, PA.

942

Changes in flexural mechanical behavior of Neomycin treated GLUT fixed aortic valve tissue

M. D. McCall¹, C. E. Eckert¹, V. M. Friebe², N. R. Vyavahare², M. S. Sacks¹;

¹Univ. of Pittsburgh, Pittsburgh, PA, ²Clemson Univ., Clemson, SC.

943

Atraumatic Braided Stent for Textile Valve Endoprosthesis

F. HEIM, C. MARCHAND;

LPMT UMR CNRS 7189, MULHOUSE, FRANCE.

944

Photoreactive, cholesterol-containing polymers enhance blood outgrowth endothelial cell attachment to polyurethane

S. J. Stachelek¹, I. Alferiev¹, M. Ueda¹, J. M. Connolly¹, R. W. Bianco², R. P. Hebbel², M. S. Sacks³, R. J. Levy¹;

¹Children's Hosp. of Philadelphia, Philadelphia, PA, ²Univ. of Minnesota, Minneapolis, MN, ³Univ. of Pittsburgh, Pittsburgh, PA.

945

Transcatheter Aortic Valve Oversizing Adversely Impacts Leaflet Kinematics, Flow Field, and Durability

A. Azadani, N. Jaussaud, L. Ge, T. Chuter, E. Tseng;

Univ. of California, San Francisco, San Francisco, CA.

946

Neomycin Enhances Glutaraldehyde Cross-linking and Glycosaminoglycan Stability in Bioprosthetic Heart Valves

V. M. Friebe;

Clemson Univ., Clemson, SC.

Urological Tissue Engineering and Biomaterials

947

Characterization of Hybrid Poloxamine/Collagen/Hyaluronan/ Hydrogel for Bladder Tissue Engineering

R. Ostendorff, B. Fleishman, J. Nagatomi;

Clemson Univ., Clemson, SC.

948

Investigation of growth factor-immobilized bioactive porous beads for the treatment of urinary incontinence

I. Kim¹, S. Oh¹, J. Lee², J. Lee², J. Lee¹;

¹Hannam Univ., Daejeon, KOREA, REPUBLIC OF, ²Catholic Univ., Seoul, KOREA, REPUBLIC OF.

949

Biodegradable Spherical Porous Polyurethane Scaffold for Urinary Bladder Tissue Engineering

E. A. Lopez¹, F. I. Simonovsky¹, J. A. Bassuk², B. D. Ratner¹;

¹Univ. of Washington, Seattle, WA, ²Univ. of Washington, Seattle Children’s Hospital Research Institute, WA.