Con-current Oral Abstract Presentations Session 5

Friday, April 23, 2010, 11:30 am - 1:00 pm

Biomaterials as Stem Cell Niche


Actin and SRF transduce physical cues from the microenvironment to regulate keratinocyte terminal differentiation

J. T. Connelly, J. E. Gautrot, D. W. Tan, B. Trappmann, W. T. S. Huck, F. M. Watt;

Univ. of Cambridge, Cambridge, UNITED KINGDOM.


Microsphere-Mediated Delivery of Retinoic Acid to Embryoid Bodies Induces Spatially Controlled Differentiation

R. L. Carpenedo, S. A. Seaman, A. M. Bratt-Leal, N. J. Bowen, J. F. McDonald, T. C. McDevitt;

Georgia Inst. of Technology, Atlanta, GA.


Pluripotent and Vascular Stem Cell Responses to Oxygen Depletion

R. E. Truitt, H. E. Abaci, G. Drazer, S. Gerecht;

Johns Hopkins Univ., Baltimore, MD.


Three-dimensional Co-culture in Micropatternable Hydrogels with Cell-Release Capabilities

T. M. Hammoudi, N. C. Bloodworth, H. Lu, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.


Proteoglycan sequestration provides spatially modulated mesenchymal stem cell proliferation

G. A. Hudalla, J. T. Koepsel, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.


Tumor Microenvironmental Cues Signal Host Tissue Progenitor Cells to Promote Tumorigenesis

E. M. Chandler, B. Seo, J. S. Lee, C. M. Berglund, B. J. Kirby, C. Fischbach;

Cornell Univ., Ithaca, NY.

Advances in Ophthalmic Biomaterials Technology


Causes of Intraocular Lens Opacification or Discoloration: Analyses of Explants

L. Werner;

John A. Moran Eye Ctr., Univ. of Utah, Salt Lake City, UT.


Sphere-Templated Polymer Scaffolds for Engineered Synthetic Cornea

S. Garty1, F. I. Simonovsky1, E. Lopez1, S. Kanayama2, T. T. Shen2, B. D. Ratner1;

1Bioengineering, Univ. of Washington, Seattle, WA, 2Ophthalmology, Univ. of Washington, Seattle, WA.


Sphere Templated Angiogenic Regeneration (STAR) Biomaterials for Ophthalmic Applications

A. J. Marshall1, S. Garty2, S. Kanayama2, T. T. Shen2, B. D. Ratner2, C. Woods3, M. G. Maginness1;

1Healionics, Seattle, WA, 2Univ. of Washington, Seattle, WA, 3TR Bio, Chandler, AZ.


Controlled and Sustained Delivery of AG1478 for Optic Nerve Regeneration

R. Robinson1, J. Lin2, C. A. Williams1, J. M. Criscione1, S. R. Viviano2, J. C. Tsai2, E. B. Lavik3;

1Yale Univ., New Haven, CT, 2Yale Univ. Sch. of Med., New Haven, CT, 3Case Western Reserve Univ., Cleveland, OH.


Super-hydrophilic Silicone Hydrogels with Phospholipid Polymer IPN for Newly Contact Lenses

K. Ishihara, T. Shimizu;

The Univ. of Tokyo, Tokyo, JAPAN.


Glistenings in Intraocular Lenses

L. Werner;

John A. Moran Eye Ctr., Univ. of Utah, Salt Lake City, UT.

Cellular Responses to Biomaterials and Cardiopathologies


Hyperglycemia amplifies the osteogenic responses in vascular cells in the presence of elastin degradation products and TGF-β1

A. Sinha;

Clemson Univ., Clemson, SC.


Correlative Light and Electron Microscopy to Determine the Fate of Polyelectrolytes in Porcine Arteries

M. Sandros, M. Tabrizian;

McGill Univ., Montreal, QC, CANADA.


Effects of Polymer Degradation on Smooth Muscle Cell Phenotype: Implications for Stent Design

L. S. Sefcik1, B. R. Wamhoff2;

1Lafayette Coll., Easton, PA, 2Univ. of Virginia, Charlottesville, VA.


Evaluation of a degradable polar hydrophobic ionic polyurethane designed for vascular graft generation in an in vitro endothelial and monocyte cell co-culture

S. M. McDonald1, L. A. Matheson1, J. E. McBane2, S. Sharifpoor2, J. P. Santerre2, R. S. Labow1;

1Univ. of Ottawa Heart Inst., Ottawa, ON, CANADA, 2Univ. of Toronto, Toronto, ON, CANADA.


A Competitive Co-culture Study on Vascular Cell Responses to Underlying Stent Topography

J. Lu, T. J. Webster;

Brown Univ., Providence, RI.


Proliferation and Phenotype of Human Coronary Artery Smooth Muscle Cells in Polyurethane Porous Scaffolds under Cyclic Mechanical Strain

S. Sharifpoor1, J. E. McBane1, C. A. Simmons1, R. S. Labow2, J. P. Santerre1;

1Univ. of Toronto, Toronto, ON, CANADA, 2Univ. of Ottawa, Ottawa, ON, CANADA.

Chemoselective Chemistry for Biomaterials


Cylic Thioester-Containing Macromonomers for Cross-Linking of Hydrogels by Native Chemical Ligation

J. Su1, B-H. Hu2, P. B. Messersmith1;

1Northwestern Univ., Evanston, IL, 2Hainan Univ., Haikou,Hainan Province, CHINA.


Facile C-terminal Attachment of Proteins on Surfaces by Hydrazine-Intein Chemical Reaction

P. Yang, S. M. Marinakos, A. Chilkoti;

Duke Univ., Durham, NC.


Chemoselective immobilization of multiple distinct peptides on SAMs for stem cell culture

G. A. Hudalla, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.


Development of Injectable Polymers that Cross-Link by Click Chemistry

M. Runge, M. J. Yaszemski;

Mayo Clinic, Rochester, MN.


Surface PEGylation via Native Chemical Ligation

E. Byun1, H. J. Lee1, S. Kang1, H. Lee2;

1#1125, Dept. of Chem. KAIST, Daejeon, KOREA, REPUBLIC OF, 2#1107, Dept. of Chem. KAIST, Daejeon, KOREA, REPUBLIC OF.


Modulating the Elasticity of Self-Assembled Matrices by Chemoselectively Crosslinking Distinct Fibril Populations

J. Z. Gasiorowski, J. H. Collier;

Univ. of Chicago, Chicago, IL.

Biofilm-Material Interactions (Symposia)


Emerging Biomaterials Strategies to Prevent Biofilm Infection

J. D. Bryers;

Univ. of Washington, Seattle, WA.


Targeted Cationic Peptide for the Disruption of Staphylococcus epidermidis Biofilm Formation

C. M. Hofmann, K. J. Bednar, J. M. Anderson, R. E. Marchant;

Case Western Reserve Univ., Cleveland, OH.


IgG biofilm adsorption is influenced by Cobalt wear debris size and can increase IL-1beta production in macrophages

A. Reddy, M. Caicedo, J. Jacobs, N. Hallab;

Rush Univ. Med. Ctr., Chicago, IL.


Presence of Biofilm on Passivated Metal: An Experimental Approach to Analyze the Sulzer Orthopaedics Inc. Recall

D. L. Williams1, S. Jeyapalina1, J. P. Beck1, K. L. Woodbury2, R. D. Bloebaum1;

1Univ. of Utah, Salt Lake City, UT, 2Dept. of VA, Salt Lake City, UT.


Effect of Protein Adsorption on Staphylococcus Epidemidis RP62A Adhesion on Polyurethane Biomaterials Surfaces

L. XU, C. A. Siedlecki;

Penn State Univ. Coll. of Med., Hershey, PA.

Emerging Frontiers in Design and Characterization of Bio-inspired Nanoscale Research & Materials


Functionalized Multi-Walled Carbon Nanotubes Impart Electrical Conductivity to Protein Biopolymer Matrices

C. M. Voge, J. Johns, J. P. Stegemann;

Univ. of Michigan Ann Arbor, Ann Arbor, MI.


Phase separation as the first step leading to hydrolytic degradation in PEG-containing polymers

S. N. Murthy, I. J. Khan, A. Luk, J. Kohn;

Rutgers Univ., Piscataway, NJ.


In Vitro Mechanical Testing of Collagen Nanofibrils

Z. L. Shen1, M. R. Dodge1, H. Kahn1, R. Ballarini2, S. J. Eppell1;

1Case Western Reserve Univ., Cleveland, OH, 2Univ. of Minnesota, Minneapolis, MN.


Charge Density Measurement of Individual Nanoparticles for the Purpose of Understanding Molecular Self-Assembly

K. E. Jarmusik1, F. R. Zypman2, S. J. Eppell1;

1Case Western Reserve Univ., Cleveland, OH, 2Yeshiva Univ., New York, NY.


Optimization and In Vitro Validation of Protease-Activated Quantum Dot Probes

N. J. Rohani;

Rice Univ., Houston, TX.


Enhanced Resistance of DNA Nanostructures to Enzymatic Digestion

J. Keum, H. Bermudez;

Univ. of Massachusetts Amherst, Amherst, MA.