Con-current Oral Abstract Presentations Session 3

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Minimally Invasive Cell and Drug Delivery Biomaterials for Posterior Segment Ocular Therapy

S. D. Fitzpatrick, J. M. A. Mazumder, B. Muirhead, H. Sheardown;

McMaster Univ., Hamilton, ON, CANADA.


Amphiphilic Dendrimer Hydrogels for Enhanced Antiglaucoma Drug Delivery

C. A. Holden1, P. Tyagi2, A. Thakur3, R. Kadam2, G. Jadhav2, U. Kompella2, H. Yang1;

1Virginia Commonwealth Univ., Richmond, VA, 2Univ. of Colorado, Denver, Denver, CO, 3Univ. of Nebraska Med. Ctr., Omaha, NE.


Coated Hydrogel Device for Controlled Release of Drugs for Cataract Surgery

F. B. Karp, S. Garty, T. T. Shen, B. D. Ratner;

Univ. of Washington, Seattle, WA.


Investigating Lubricin to Prevent Post-operative Infection of Intraocular Lenses Following Cataract Surgery

G. E. Aninwene, II, E. N. Taylor, A. Mei, G. D. Jay, T. J. Webster;

Brown Univ., Providence, RI.


Tissue Engineered Human Corneal Stromal Tissue

J. Wu, Y. Du, J. L. Funderburgh, W. R. Wagner;

Univ. of Pittsburgh, Pittsburgh, PA.


Design of Silicone Materials for Ophthalmic Applications

C. B. Hu, D. Pham, M. Lowery, R. Jain;

Abbott Med. Optics, Santa Ana, CA.


Phospholipid Delivery from a Silicone Hydrogel Contact Lens

W. G. Pitt1, Y. Zhao1, D. R. Jack1, J. L. Nelson2, J. L. Pruitt2;

1Brigham Young Univ., Provo, UT, 2CIBA VISION Global Res., Duluth, GA.


Optical Transparency and In Vitro Biocompatibility of Recombinant Silk-Elastinlike Protein Polymer

W. Teng1, J. Cappello2, X. Wu1;

1Univ. of Arizona, Tucson, AZ, 2Protein Polymer Technologies, Inc., San Diego, CA.

Biologically Derived Materials


Efficacy Of An Injectable Dual Release Delivery System For Halting Perthes Disease

Y. Zou1, J. Horstmann1, T. Milbrandt2, V. Talwalkar2, D. Puleo1;

1Univ. of Kentucky, Lexington, KY, 2Shriners Hosp. for Children, Lexington, KY.


A Biologic Scaffold Composed of Skeletal Muscle Extracellular Matrix

M. T. Wolf, K. A. Daly, J. E. Reing, S. F. Badylak;

Univ. of Pittsburgh, Pittsburgh, PA.


Preparation of an Artificial Skin by Replication of Its Structure and Function Using Fibrillogenesis

K. Nam, Y. Sakai, T. Kimura, A. Kishida;

Div. of Biofunctional Molecules, Inst. of Biomaterials and Bioengineering,, Tokyo, JAPAN.


Incorporation of bFGF in an Injectable Pericardial Matrix Gel for Myocardial Tissue Engineering

S. B. Seif-Naraghi, D. Horn, P. Schup-Magoffin, K. L. Christman;

UC San Diego, La Jolla, CA.


Effect of Chemical and Enzymatic Crosslinking of Novel Porous Soy Protein Scaffolds on Human Mesenchymal Stem Cell Morphology and Growth

K. B. Chien1, R. N. Shah2;

1Northwestern Univ., Evanston, IL, 2Northwestern Univ., Chicago, IL.


Towards Molecular Farming of a Human Elastin-like Polymer in Plants

M. Martinuzzi1, S. Marchetti1, A. Bandiera2, S. Fare3, M. Tanzi3;

1Università degli Studi di Udine, UDINE, ITALY, 2Università degli studi di Trieste, TRIESTE, ITALY, 3Politecnico di Milano, MILANO, ITALY.


Dynamic Culturing of Bone Marrow Mesenchymal Stem Cells in Chitosan-Glycosaminoglycan Scaffolds for Heart Valve Tissue Engineering

M. Z. Albanna1, T. H. Bou-Akl1, H. L. Walters, III2, H. W. T. Matthew1;

1Wayne State Univ., Detroit, MI, 2Children's Hosp. of Michigan, Detroit, MI.


Comparison of Three Methods of Derivation of a Biologic Scaffold Composed of Adipose Tissue Extracellular Matrix

B. N. Brown1, J. M. Freund2, L. Han2, J. P. Rubin2, J. E. Reing2, E. M. Jeffries2, M. T. Wolf2, S. Tottey2, C. A. Barnes3, B. D. Ratner3, S. F. Badylak2;

1Cornell Univ., Ithaca, NY, 2Univ. of Pittsburgh, Pittsburgh, PA, 3Univ. of Washington, Seattle, WA.

Biomaterials-based Therapies Exploiting Immunological Processes


Controlled Release Formulations for Increasing Local Numbers of Regulatory T Cells

S. Jhunjhunwala, G. Raimondi, E. Nichols, S. H. Thorne, A. W. Thomson, S. R. Little;

Univ. of Pittsburgh, Pittsburgh, PA.


Local Liposomal Delivery of Anti-CD40 and CpG Stimulates an Anti-Tumor Response while Minimizing Systemic Side Effects

B. Kwong, H. Liu, D. J. Irvine;

Massachusetts Inst. of Technology, Cambridge, MA.


Self-Assembling Adjuvants That Raise Strong Antibody Responses Against Protein Antigens

G. A. Hudalla, J. Modica, M. Mrksich, J. H. Collier;

Univ. of Chicago, Chicago, IL.


A Novel RAFT Block Copolymer for Anti-Inflammatory Protein Delivery

R. E. Whitmire, D. S. Wilson, N. Murthy, A. J. Garcia;

Georgia Inst. of Technology, Atlanta, GA.


Encapsulation within Reductive Polymersomes Enhances the Adjuvant Effect of Gardiquimod on Murine Splenocytes

E. A. Scott1, A. Stano1, P. Wanakule2, M. Swartz1, J. Hubbell1;

1École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, SWITZERLAND, 2The Univ. of Texas at Austin, Austin, TX.


Targeted Activation of Antigen Presenting Cells with Mannose-Modified Polyanhydride Nanoparticles

A. V. Chavez-Santoscoy, B. Carrillo-Conde, E-H. Song, Y. Phanse, A. Ramer-Tait, N. Pohl, M. Wannemuehler, B. Bellaire, B. Narasimhan;

Iowa State Univesity, Ames, IA.


Targeted, Immunosuppressive Microparticles Modify Immune Cell Behavior For The Prevention Of Autoimmune Diabetes In Mice

J. S. Lewis, M. Carstens, C. Q. Xia, M. J. Clare-Salzler, B. G. Keselowsky;

Univ. of Florida, Gainesville, FL.


Lymph Node Injection of Adjuvant-loaded Microparticles Elicits Viral Vector-level T-cell Response Without Boosting

C. M. Jewell, D. J. Irvine;

Massachusetts Inst. of Technology, Cambridge, MA.

Drug Delivery from Implant Surfaces


Enhancing Bone Allograft Integration Through Local Delivery of Sphingosine 1-phosphate Receptor Targeted Drugs

C. S. Huang, S. S. Tholpady, E. A. Botchwey;

Univ. of Virginia, Charlottesville, VA.


Effect of Processing Methods on Drug Release Profiles of Anti-Restenotic Self-Assembled Monlayers

S. E. Stoebner, G. Mani;

The Univ. of South Dakota, Sioux Falls, SD.


CAP-Pluronic Film Based Multiple Drug Delivery System

S. C. Sundararaj, M. V. Thomas, T. D. Dziubla, D. A. Puleo;

Univ. of Kentucky, Lexington, KY.


Activated Adhesives for Delivery of Drug Impregnated Thin Films on Vascular Tissues

E. B. Nguyen;

Nanyang Technological Univ., Singapore, SINGAPORE.


The Influence of Crystalline PEG on Paclitaxel Drug Release in PEG/PLGA Thin Films

C. L. Huang;

Nanyang Technological Univ., Singapore, SINGAPORE.


Synthesis and Characterization of Poly (triethylene glycol methyl acrylate-co-α-tocopheryl acrylate): a Water Soluble Antioxidant Polymer Derivative to Enable Localized Neuroprotection

Y. Cao, W. He;

Univ. of Tennessee, knoxville, TN.


Sustained Protein Delivery from Coated Surgical Sutures

J. Lee, Y. Lu, G. S. Baer, M. D. Markel, W. L. Murphy;

Univ. of Wisconsin, Madison, WI.


Development of a Porous Poly-L-lactic Acid Dexamethasone Releasing Sleeve for Biosensor Design

S. G. Vallejo-Heligon, W. M. Reichert;

Duke Univ., Durham, NC.