Con-current Oral Abstract Presentations Session 1

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Cardiovascular Biomaterials

1

Long Term in vivo Study of Rapidly Degradable Synthetic Arterial Grafts

cardiovascular; regenerative medicine; vascular graft

R. A. Allen, University of Pittsburgh, Pittsburgh, PA

W. Wu, Qindu Hospital, Fourth Military Medical University, Xi'an, China

M. Yao, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

D. Dutta, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, Pennsylvania

X. Duan, University of Pittsburgh, Pittsburgh, Pennsylvania

T. N. Bachman, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

H. C. Champion, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

D. B. Stolz, University of Pittsburgh, Pittsburgh, Pennsylvania

A. M. Robertson, University of Pittsburgh, Pittsburgh, Pennsylvania

K. Kim, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, Pennsylvania

J. S. Isenberg, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Y. Wang, University of Pittsburgh, Pittsburgh, Pennsylvania

2

Bioactive anti-apoptotic coating: from 2D substrates to 3D commercial stent grafts for in vivo testing

coating(s); in vivo; vascular

P. Lequoy, Ecole de Technologie Superieure, Montreal, QC, Canada

M. Sbai, Ecole de Technologie Supérieure, Montreal, Québec, Canada

B. Saoudi, Ecole Polytechnique de Montreal, Montreal, Québec, Canada

A. Bertrand-Grenier, Universite de Montreal, Montreal, Québec, Canada

M. Wertheimer, Ecole polytechnique de Montreal, Montreal, Québec, Canada

G. Soulez, Universite de Montreal, Montreal, Québec, Canada

S. Lerouge, Ecole de technologie superieure, Montreal, Québec, Canada

3

Catheter-deliverable, Thermal and pH Responsive Hydrogels for Delivery of Cardiac Progenitor Cells into Infarcted Hearts

cardiovascular; catheter; cell therapy

J. Guan, The Ohio State University, Columbus, OH

4

Pro-angiogenic and Anti-inflammatory Biomaterial Therapies for Peripheral Artery Disease

angiogenesis/neovascularization; inflammation; scaffolds

A. L. Zachman, Vanderbilt University, Nashville, TN

J. Ticker-Schwartz, Vanderbilt University, Nashville, Tennessee

F. Shen, Vanderbilt University, Nashville, Tennessee

S. Fitzpatrick, Vanderbilt University, Nashville, Tennessee

M. Skala, Vanderbilt University, Nashville, Tennessee

H. Sung, Vanderbilt University, Nashville, Tennessee

5

Stacked collagen film enabled engineered small vascular graft

collagen; hemocompatibility

Y. Kim, University of Texas at Arlington, Arlington, TX

S. Shah, University of Texas at Arlington, Arlington, Texas

J. Ahmed, University of Texas at Arlington, Arlington, Texas

6

Effects Of Electrical Stimulation and Insulin-like Growth Factor On Heart Cells Cultured On A Microfabricated Degradable Elastomer

tissue engineering

H. Park, C.S. Draper Laboratory, Cambridge, MA

B. L. Larson, MIT, Cambridge, Massachusetts

M. E. Kolewe, MIT, Cambridge, Massachusetts

G. Vunjak-Novakovic, Columbia University, New York, New York

L. E. Freed, C.S. Draper Laboratory; MIT, Cambridge, Massachusetts

7

Mutli-Arm PEG Hydrogels Containing Collagen Sequence and Cell-Adhesive Sequence Support Enzyme Mediated Degradation and Endothelial Cell Proliferation

biodegradation; cell adhesion; hydrogel

D. R. Jones, Case Western Reserve University, Cleveland Heights, OH

8

An Endothelium Simulating Multifunctional Nanomatrix for Drug Eluting Stents

stents

H. Jun, University of Alabama at Birmingham, Birmingham, AL

A. Andukuri, University of Alabama at Birmingham, Birmingham, Alabama

Y. Sohn, Emory University, Atlanta, Georgia

Y. Yoon, Emory University, Atlanta, Georgia

B. Brott, University of Alabama at Birmingham, Birmingham, Alabama

Drug Delivery1

9

Injectable Scaffolds with Degradable Calcium Alginate Beads as a Cell Delivery System for Tissue Repair

cell therapy; encapsulated cells; polyurethane(s)

R. Guo, Vanderbilt University, Nashville, TN

C. L. Ward, United States Army Institute of Surgical Research, Fort Sam Houston, Texas

S. A. Guelcher, Vanderbilt University, Nashville, Tennessee

10

Novel Sugar-Glass Nanoparticles system for Biomolecules Stabilization and Delivery in Tissue Engineering Applications

diabetes; nanomaterials/nanophase; nanotechnology

j. Giri, Parffenbarg Research Center,, Gaithersburg, MD

11

A pro-healing polyHEMA scaffold as an antibiotic-releasing insert for a scleral bandage

drug delivery/release; ophthalmic; pHEMA

A. Galperin, University of Washington, Seattle, WA

K. Smith, University of Washington, Seattle, Washington

J. Bryers, University of Washington, Seattle, Washington

T. Shen, University of Washington, Seattle, Washington

B. Ratner, University of Washington, Seattle, Washington

12

Sequential drug delivery - in vitro and in vivo

controlled release; dental/craniofacial material; drug delivery/release

S. Sundararaj, University of Kentucky, Lexington, KY

M. Thomas, University of Kentucky, Lexington, Kentucky

M. Al-Sabbagh, University of Kentucky, Lexington, Kentucky

T. Dziubla, University of Kentucky, Lexington, Kentucky

D. Puleo, University of Kentucky, Lexington, Kentucky

13

Tunable Dual Growth Factor Delivery Using Multilayered Microparticles with Controllable Degradation Kinetics

controlled release; drug delivery/release; growth factor

X. Yu, University of Wisconsin-Madison, Madison, WI

14

Development of a pH-responsive hydrogel network for the oral delivery of human growth hormone

hydrogel; polymer

S. D. Steichen, The University of Texas at Austin, Austin, TX

N. Peppas, The University of Texas at Austin, Austin, Texas

15

Self-Assembled Micellar Complex Comprised of Green Tea Catechin Derivatives for Protein Drug Delivery

drug delivery/release; nanotechnology; tumor

S. Tan, Institute of Bioengineering and Nanotechnology, Singapore, Singapore

16

Controlled Protein Release from Layer-by-Layer Coated Hydrogel Scaffolds for Nerve Repair

controlled release; drug delivery/release; nerve regeneration

D. A. Lynam, Michigan State University, East Lansing, MI

D. Shahriari, Michigan State University, East Lansing, Michigan

P. Angart, Michigan State University, East Lansing, Michigan

K. Koffler, University of California-San Diego, La Jolla, California

C. Chan, Michigan State University, East Lansing, Michigan

P. Walton, Michigan State University, East Lansing, Michigan

M. Tuszynski, University of California-San Diego, La Jolla, California

J. Sakamoto, Michigan State University, East Lansing, Michigan

Surface Characterization and Modification1

17

Nanofiber mediated osteoinduction through RhoA GTPase signaling

adhesion; atomic force microscopy; bone

T. Ozdemir, The Pennsylvania State University, University Park, PA

18

Nonfouling and Functionalizable Hydrogels based on Polyampholyte Chemistries

adsorption; biocompatibility/soft tissue; hydrogel

M. T. Bernards, University of Missouri, Columbia, MO

M. Schroeder, University of Missouri, Columbia, Missouri

D. E. McGrath, University of Missouri, Columbia, Missouri

K. M. Zurick, University of Missouri, Columbia, Missouri

19

Studying the Synergistic Effect of Coatings and Nitric Oxide release on Platelet Adsorption

coating(s)

K. A. Amoako, University of Washington, Seattle, Seattle, WA

20

Surface Modification of a Poly(Glycolic-co-Lactic Acid) – Poly(DL-Lactide-co-Caprolactone) Small-Diameter Vascular Graft via CD34 Antibody Immobilization to Enhance Cell Attachment

endothelialization; surface modification; vascular graft

A. J. Melchiorri, University of Maryland, College Park, MD

N. Hibino, Children's National Medical Center, District of Columbia, District of Columbia

J. P. Fisher, University of Maryland, College Park, Maryland

21

Migrating versus Stationary Applied Pressure Changes Lubricity of Hydrogel Surfaces

hydrogel; stress; tribology

A. C. Dunn, University of Florida, Gainesville, FL

J. Uruena, University of Florida, Gainesville, Florida

T. E. Angelini, University of Florida, Gainesville, Florida

W. Sawyer, University of Florida, Gainesville, Florida

22

Controlled End-functionality of Thermoresponsive Polymer Brushes for Regulating Thermally Induced Surface Cell Adhesion Behavior

biomimetic; cell adhesion; polymer

N. MATSUZAKA, Tokyo University of Science, Chiba, Japan

M. NAKAYAMA, Institure of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University (TWIns), Tokyo, Japan

H. TAKAHASHI, Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University (TWIns), Tokyo, Japan

T. ASOH, Tokyo University of Science, Chiba, Japan

A. KIKUCHI, Tokyo University of Science, Chiba, Japan

T. OKANO, Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University (TWIns), Tokyo, Japan

23

Biofunctional Thermo-Responsive Polymeric Surface with Micropatterns for Controlling Cell Attachment and Detachment

cell adhesion; microstructure; surface modification

Y. Kumashiro, Tokyo Women's Medical University, Tokyo, Japan

24

Silicone Elastomers with Intrinsic Control of Surface Hydrophilicity

hydrophilic; silicone(s) PDMS; surface modification

J. D. Goff, Gelest, Morrisville, PA

B. Arkles, Gelest, Morrisville, Pennsylvania

Tissue Engineering1

25

Self-Assembly of Biomaterials for Bone Tissue Morphogenesis

bone; growth factor; regenerative medicine

N. J. Shah, Massachusetts Institute of Technology, Cambridge, MA

M. Hyder, Massachusetts Institute of Technology, Cambridge, Massachusetts

M. Spector, Massachusetts Institute of Technology, VA Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

P. T. Hammond, Massachusetts Institute of Technology, Cambridge, Massachusetts

26

Biofabrication of Innervated Muscle Tissue for Accelerated Restoration of Muscle Function

muscle; tissue engineering

S. Lee, Wake Forest School of Medicine, Winston-Salem, NC

27

S1P Receptor Specific Drug Enhances Mandibular Defect Healing by Modulating Local Inflammation, Enhancing Neovascularization and  Increasing Progenitor Cell Recruitment.

maxillofacial; tissue engineering; vascular

A. Das, University of Virginia, Charlottesville, VA

B. Hughley, University of Virginia, Charlottesville, Virginia

C. Segar, Gatech, Atlanta, Georgia

E. Botchwey, Gatech, Atlanta, Georgia

28

Long-term static culture and fatigue testing of a bi-continuous hydrogel-elastomer scaffold for nucleus pulposus repair

intervertebral disk; scaffolds; tissue engineering

J. W. S. Hayami, Queen's University, Kingston, ON, Canada

B. G. Amsden, Queen's University, Kingston, Ontario, Canada

S. D. Waldman, Queen's University, Kingston, Ontario, Canada

29

Co-culture Separation and Assembly by Nanotopographical Persuasion of Cells

endothelial cells; stents; tissue engineering

P. M. Reynolds, University of Glasgow, Glasgow, United Kingdom (Great Britain)

R. H. Pedersen, University of Glasgow, Glasgow, United Kingdom (Great Britain)

M. J. Dalby, University of Glasgow, Glasgow, United Kingdom (Great Britain)

M. O. Riehle, University of Glasgow, Glasgow, United Kingdom (Great Britain)

N. Gadegaard, University of Glasgow, Glasgow, United Kingdom (Great Britain)

30

3D Transdifferentiation of Human Mesenchymal Stem Cells into Hepatocyte-Like Cells Using Bioprinted Scaffolds

bioactive material; cell differentiation; tissue engineering

K. B. Chien, Northwestern University, Chicago, IL

A. E. Jakus, Northwestern University, Chicago, Illinois

R. N. Shah, Northwestern University, Chicago, Illinois

31

Human ECM Particles as an Injectable Bulking Agent for Adipose Replacement

biocompatibility/soft tissue; extracellular matrix

A. Young, University of California, San Diego, La Jolla, CA

T. McAllister, Cytograft, Inc, Novato, California

N. Dusserre, Cytograft, Inc, Novato, California

K. Christman, University of California, San Diego, La Jolla, California

N. L'Heureux, Cytograft, Inc., Novato, California

32

Fabrication of Vascularized 3D-Wound Healing Fibrous Tissues and Application for In Vitro Tumor Invasion Models

angiogenesis/neovascularization; tumor; wound healing

A. Nishiguchi, Osaka University, Osaka, Japan

M. Matsusaki, Osaka University, Osaka, Japan

M. Akashi, Osaka University, Osaka, Japan