Con-current Oral Abstract Presentations Session 6

Novel conduits for Schwann Cell Induced Spinal Cord Repair

controlled release; nerve regeneration; smart materials

Y. Lee, University of Miami, Miami, FL

S. Wu, New Jersey Institute of Technology, Newark, New Jersey

I. Sidhu, New Jersey Institute of Technology, Newark, New Jersey

T. Livingston Arinzeh, New Jersey Institute of Technology, Newark, New Jersey

M. B. Bunge, University of Miami, Miami, Florida

Superporous Extracellular Matrix Mimics for On-demand Release of Growth Factors Based on Nucleic Acid Aptamers and Superporous Hydrogels

controlled release; extracellular matrix; hydrogel

M. R. Battig, University of Connecticut, Storrs, CT

N. Chen, University of Connecticut, Storrs, Connecticut

Y. Wang, University of Connecticut, Storrs, Connecticut

Thrombin-responsive hydrogels with varied cleavage kinetics

controlled release; hemocompatibility; heparin

C. Sperling, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

M. Rentsch, Leibniz-Institute of Polymer Research Dresden / Hochschule Zittau/Görlitz, Dresden, Germany

M. Tsurkan, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

U. Freudenberg, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

M. F. Maitz, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

C. Werner, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

Thermo-responsive citrate-based nanonets for tissue regeneration: effects of localized SDF-1 release

biocompatibility/soft tissue; controlled release; regenerative medicine

J. Yang, Northwestern University, Evanston, IL

J. Yang, Northwestern University, Evanston, Illinois

R. Hoshi, Northwestern University, Evanston, Illinois

K. Baler, Northwestern University, Evanston, Illinois

G. Ameer, Northwestern University, Evanston, Illinois

Novel Biomimetic Proteoglycans for Molecular Engineering of Degenerated Tissue

biomimetic

K. Prudnikova, Drexel University, Philadelphia, PA

S. Lightfoot Vidal, Drexel University, Philadelphia, Pennsylvania

E. Vresilovic, Pennsylvania State College of Medicine, Hershey, Pennsylvania

M. Marcolongo, Drexel University, Philadelphia, Pennsylvania

Protease Triggered Release of Macromolecules from MMP-sensitive Hyaluronic Acid Hydrogels

biodegradation; drug delivery/release; hydrogel

B. P. Purcell, University of Pennsylvania, Philadelphia, PA

M. Charati, University of Pennsylvania, Philadelphia, Pennsylvania

R. Wade, University of Pennsylvania, Philadelphia, Pennsylvania

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

Heparin functionalized thermoresponsive cell culture surfaces for regulating affinity interaction with basic fibroblast growth factor and enhancing cell sheet formation

cell-material interactions; growth factor; smart materials

J. Kobayashi, Tokyo Women's Medical University, Tokyo, Japan

Biomimetic Calcium Carbonate Concentric Microgrooves for Promoting MC3T3-E1 Cell Functions

calcium salts/compounds; cell adhesion; cell differentiation

S. Wang, The University of Tennessee, Knoxville, TN

X. Wu, The University of Tennessee, Knoxville, Tennessee

Cartilage Matrix Gels Promote Chondrogenesis of Human Mesenchymal Stem Cells

cartilage; extracellular matrix; stem/progenitor cells

O. A. Burnsed, Georgia Institute of Technology, Atlanta, GA

R. Olivares-Navarrete, Georgia Institute of Technology, Atlanta, Georgia

S. L. Hyzy, Georgia Institute of Technology, Atlanta, Georgia

K. O. Marchand, Georgia Institute of Technology, Atlanta, Georgia

B. D. Boyan, Georgia Institute of Technology, Atlanta, Georgia

Z. Schwartz, Georgia Institute of Technology, Atlanta, Georgia

Engineering Vascularized Skin Flap with Decellularized Skin Flap Matrix Scaffold

cell culture; extracellular matrix; tissue engineering

L. Wang, UT MD Anderson Cancer Center, Houston, TX

Q. Zhang, UT MD Anderson Cancer Center, Houston, Texas

J. A. Johnson, UT MD Anderson Cancer Center, Houston, Texas

D. W. Chang, UT MD Anderson Cancer Center, Houston, Texas

Bioskiving: Bioinspired Fabrication of Nanostructures from Tissue Slices

nanotechnology

Q. Xu, Tufts University, Medford, MA

Production of Recombinant Bacterial Collagens for Use as New Materials for Biomedical Applications

collagen

J. A. M. Ramshaw, CSIRO - Materials Science and Engineering, Clayton, Australia

Y. Y. Peng, CSIRO - Materials Science and Engineering, Clayton, Australia

V. Stoichevska, CSIRO - Materials Science and Engineering, Clayton, Australia

L. Howell, CSIRO - Materials Science and Engineering, Clayton, Australia

S. Madsen, CSIRO - Materials Science and Engineering, Clayton, Australia

G. Dumsday, CSIRO - Materials Science and Engineering, Clayton, Australia

J. Werkmeister, CSIRO - Materials Science and Engineering, Clayton, Australia

In vivo potential of functionally graded platelet lysates scaffolds for osteochondral repair

bioactive material; in vivo; tissue engineering

V. E. Santo, University of Minho - 3B's Research Group, Caldas das Taipas, Portugal

A. R.C. Duarte, University of Minho - 3B's Research Group, Caldas das Taipas, Portugal

P. P. Carvalho, University of Minho, 3B's Research Group, Caldas das Taipas, Portugal

J. F. Requicha, University of Minho, 3B's Research Group, Caldas das Taipas, Portugal

C. A.A. Viegas, University of Trás-os-Montes e Alto Douro, Department of Veterinary Sciences, Vila Real, Portugal

I. R. Dias, University of Trás-os-Montes e Alto Douro, Department of Veterinary Sciences, Vila Real, Portugal

J. F. Mano, University of Minho, 3B's Research Group, Caldas das Taipas, Portugal

M. E. Gomes, University of Minho, 3B's Research Group, Caldas das Taipas, Portugal

R. L. Reis, University of Minho, 3B's Research Group, Caldas das Taipas, Portugal

Hyaluronic acid Hydrogels Synthesized by Thiol-ene Step Growth Polymerization

hydrogel; surface modification

W. M. Gramlich, University of Pennsylvania, Philadelphia, PA

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

Chronic Blood Brain Barrier Breach Contributes to Intracortical Electrode Recording Failure

inflammation; neural prosthesis; wound healing

T. Saxena, Georgia Institute of Technology, Atlanta, GA

L. Karumbaiah, Georgia Institute of Technology, atlanta, Georgia

E. Gaupp, Georgia Institute of Technology, Atlanta, Georgia

K. Patil, garrett.stanley@bme.gatech.edu, Atlanta, Georgia

R. Patkar, Georgia Institute of Technology, atlanta, Georgia

M. Betancur, Georgia Institute of Technology, Atlanta, Georgia

G. Stanley, Georgia Institute of Technology, Atlanta, Georgia

R. Bellamkonda, Georgia Institute of Technology, Atlanta, Georgia

Mechanical Evaluation of an Ultrafast Degrading Polymer as a Temporary Coating for Neural Probes

biocompatibility/soft tissue; bioresorbable; polymer

J. Kohn, Rutgers - The State University of New Jersey, Piscataway, NJ

S. Wang, Rutgers - The State University of New Jersey, Piscataway, New Jersey

J. Lo, Rutgers - The State University of New Jersey, Piscataway, New Jersey

S. Singh, Rutgers - The State University of New Jersey, Piscataway, New Jersey

J. Zahn, Rutgers - The State University of New Jersey, Piscataway, New Jersey

D. Shreiber, Rutgers - The State University of New Jersey, Piscataway, New Jersey

Biomaterials and Electrode Strategies in Regenerative Peripheral Nerve Interfaces

electrodes; nerve regeneration; neural prosthesis

N. B. Langhals, University of Michigan, Ann Arbor, MI

J. V. Larson, University of Michigan, Ann Arbor, Michigan

T. A. Kung, University of Michigan, Ann Arbor, Michigan

K. B. Sugg, University of Michigan, Ann Arbor, Michigan

J. D. Moon, University of Michigan, Ann Arbor, Michigan

P. S. Cederna, University of Michigan, Ann Arbor, Michigan

M. G. Urbanchek, University of Michigan, Ann Arbor, Michigan

Flexible and Kink-Resistant Braided Conduits for Peripheral Nerve Regeneration

in vivo; mechanical properties; nerve regeneration

B. A. Clements, Rutgers - The State University of New Jersey, Piscataway, NJ

J. Bushman, Rutgers - The State University of New Jersey, Piscataway, New Jersey

S. Murthy, Rutgers - The State University of New Jersey, Piscataway, New Jersey

J. Kohn, Rutgers - The State University of New Jersey, Piscataway, New Jersey

Microchannel Scaffolds as Regenerative Peripheral Nerve Interfaces

implant design; nerve regeneration; neural prosthesis

A. Srinivasan, Georgia Institute of Technology, Atlanta, GA

A. Haque, Georgia Institute of Technology, Atlanta, Georgia

M. Tahilramani, Georgia Institute of Technology, Atlanta, Georgia

R. V. Bellamkonda, Georgia Institute of Technology, Atlanta, Georgia

G. B. Stanley, Georgia Institute of Technology, Atlanta, Georgia

SDF-1α-loaded Dextran Sulfate/Chitosan Nanoparticles As a Multi-pronged Approach to Enhance Neural Stem Cell Infiltration into Hydrogels for CNS Applications

nanomaterials/nanophase; nerve regeneration; stem/progenitor cells

T. Lim, Massachusetts Institute of Technology, Cambridge, MA

S. Rokkappanavar, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

M. Kurisawa, Institute of Bioengineering and Nanotechnology, Singapore, Singapore

M. Spector, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

Novel Rapidly-Gelling Injectable Chitosan Sponge to Promote Oligodendrocyte Progenitor Cells’ Differentiation

regenerative medicine; spinal implant; stem/progenitor cells

M. Mekhail, McGill, Montreal, QC, Canada

G. Almazan, McGill, Montreal, Québec, Canada

M. Tabrizian, McGill, Montreal, Québec, Canada

Enhancement of Astrocyte Migration Through Collagen-Genipin Gels in Response to Fibroblast Growth Factor-2

cell-material interactions; collagen; nerve regeneration

D. Macaya, Massachusetts Institute of Technology, brookline, MA

K. Hayakawa, Massachusetts General Hospital, Charlestown, Massachusetts

K. Arai, Massachusetts General Hospital, charlestown, Massachusetts

M. Spector, VA Medical Center Boston, Massachusetts Institute of Technology, Jamaica Plain, Massachusetts

Control of Mesenchymal Stem Cell Phenotype and Microenvironment through Intracellular Particles

drug delivery/release; stem/progenitor cells

J. A. Ankrum, MIT, Cambridge, MA

O. Faii, MIT, Cambridge, Massachusetts

O. Levy, MIT, Cambridge, Massachusetts

J. Karp, MIT, Cambridge, Massachusetts

Dual stimuli-responsive antioxidant nanoparticles based on polymeric prodrugs of vanillin

drug delivery/release; inflammation; nanomedicine

J. Kim, Department of BIN Fusion Tech. Chonbuk National University, Jeonju-si, Republic of Korea

Enhanced Intracellular Peptide Delivery with pH-responsive, Endosomolytic Nano-Polyplexes to Prevent Intimal Hyperplasia in Human Saphenous Vein Grafts

drug delivery/release; polymer; vascular graft

B. C. Evans, Vanderbilt University, Nashville, TN

K. M. Hocking, Vanderbilt University, Nashville, Tennessee

C. M. Brophy, Vanderbilt Heart and Vascular Institute, Nashville, Tennessee

C. L. Duvall, Vanderbilt University, Nashville, Tennessee

Amphiphilic Nanoparticles as Molecular Therapeutics for Atherosclerosis

bioactive material; cardiovascular; cell-material interactions

L. Petersen, Rutgers University, Piscataway, NJ

A. York, Rutgers Unviersity, Piscataway, New Jersey

S. Ahuja, Rutgers University, Piscataway, New Jersey

S. Gadamsetty, Rutgers University, Piscataway, New Jersey

K. Uhrich, Rutgers University, Piscataway, New Jersey

R. Prud’homme, Princeton University, Princeton, New Jersey

P. Moghe, Rutgers University, Piscataway, New Jersey

Biocompatible polymeric nanoparticles degrade and release cargo in response to biologically relevant levels of hydrogen peroxide

biosensors/biochips; nanomedicine

A. Almutairi, University of California, San Diego, La Jolla, CA

C. de Gracia Lux, University of California, San Diego, La Jolla, California

S. Joshi-Barr, University of California, San Diego, La Jolla, California

T. Nguyen, University of California, San Diego, La Jolla, California

E. Mahmoud, University of California, San Diego, La Jolla, California

N. Fomina, University of California, San Diego, La Jolla, California

Antioxidant nanoparticles for inhibition of inflammation-mediated rheumatoid arthritis

in vivo; inflammation; polymer

D. Cochran, University of Kentucky, Lexington, KY

Development of a Poly(lactic acid) Poly(ethylene glycol) Nanoparticle for Delivery of Vitamin D3 for Severe Asthmatics

cell culture; drug delivery/release; inflammation

N. K. Comolli, Villanova University, Villanova, PA

R. Lojek, Villanova University, Villanova, Pennsylvania

A. Banerjee, University of Pennsylvania, Philadelphia, Pennsylvania

R. Panettieri, Jr., University of Pennsylvania, Philadelphia, Pennsylvania

Antigen-Specific Immune Response of Microparticle Vaccine Containing CpG-ODN and Protein

drug delivery/release; immune response; microspheres

Q. Wang, Baylor College of Medicine, Houston, TX

M. A. Barry, Baylor College of Medicine, Houston, Texas

M. Knight, Southwest Electronic Medical Research Institute, Houston, Texas

C. M. Beaumier, Baylor College of Medicine, Houston, Texas

M. J. Heffernan, Baylor College of Medicine, Houston, Texas

Electrospun Osteoconductive and Osteoinductive Bicomponent Scaffolds: Controlled Release of rhBMP-2 and Enhanced Biological Performance of Scaffolds

osteogenesis; sustained release; tissue engineering

C. Wang, The University of Hong Kong, Hong Kong SAR, Hong Kong

M. Wang, The University of Hong Kong, Hong Kong SAR, Hong Kong

Bone Morphogenetic Protein 2 Induces an Inflammatory Profile in MSCs on Microstructured Titanium

dental/endosteal implant; growth factor; inflammation

S. L. Hyzy, Georgia Institute of Technology, Atlanta, GA

R. Olivares-Navarrete, Georgia Institute of Technology, Atlanta, Georgia

S. Ortman, Georgia Institute of Technology, Atlanta, Georgia

B. D. Boyan, Georgia Institute of Technology, Atlanta, Georgia

Z. Schwartz, Georgia Institute of Technology, Atlanta, Georgia

Polydopamine-Coated PDMS-PCL Shape Memory Polymer Foams for Bone Regeneration

bioactive material; bone graft; osteogenesis

A. Jimenez-Vergara, Rensselaer Polytechnic Institute, Troy, NY

D. J. Munoz-Pinto, Rensselaer Polytechnic Institute, Troy, New York

D. Zhang, Texas A&M University, College Station, Texas

M. Grunlan, Texas A&M University, College Station, Texas

M. S. Hahn, Rensselaer Polytechnic Institute, Troy, New York

Sustained Bone Morphogenetic Protein 2 Delivery from Densified Titanium for the Hard Tissue Engineeering

controlled release; growth factor; titanium (alloys)

H. Jung, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea

T. Jang, Seoul National Univ., Seoul, Republic of Korea

M. Kang, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Seoul, Republic of Korea

H. Park, Seoul National Univ., Seoul, Republic of Korea

H. Kim, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Seoul, Republic of Korea

Y. Estrin, Department of Materials Engineering, Monash University, Clayton, Australia, Clayton, Australia

Y. Koh, Korea Univ., Seoul, Republic of Korea

Molecule Release from Proteolytically Degradable Hyaluronic Acid Hydrogels for Improved Osteogenesis

biodegradation; bone; hydrogel

J. L. Holloway, University of Pennsylvania, Philadelphia, PA

B. Purcell, University of Pennsylvania, Philadelphia, Pennsylvania

S. Khetan, University of Pennsylvania, Philadelphia, Pennsylvania

J. A. Burdick, University of Pennsylvania, Philadelphia, Pennsylvania

Enhanced Osteogenic Differentiation of Adipose-Derived Stem Cells in Growth Factor Presenting Gelatin Hydrogels

bone; growth factor; tissue engineering

J. E. Samorezov, Case Western Reserve University, Cleveland, OH

E. Alsberg, Case Western Reserve University, Cleveland, Ohio

Bone Regenerative Capacity of rhBMP-2 Loaded Carboxymethylchitosan Microspheres in a Rat Calvarial Defect

dental/craniofacial material; growth factor; in vivo

B. Reves, University of Memphis, Memphis, TN

J. A. Jennings, University of Memphis, Memphis, Tennessee

P. Konofaos, University of Tennessee Health Science Center, Memphis, Tennessee

D. Petersen, University of Tennessee Health Science Center, Memphis, Tennessee

R. Wallace, University of Tennessee Health Science Center, Memphis, Tennessee

R. Smith, University of Tennessee Health Science Center, Memphis, Tennessee

T. Guda, University of Texas at San Antonio, San Antonio, Texas

M. Appleford, University of Texas at San Antonio, San Antonio, Texas

W. O. Haggard, University of Memphis, Memphis, Tennessee

J. D. Bumgardner, University of Memphis, Memphis, Tennessee

Controlling Secretion of VEGF from 3D Stem Cell Aggregates to Enhance Osteochondral Bone Regeneration

osteogenesis; stem/progenitor cells; tissue engineering

J. O. Blanchette, University of South Carolina, Columbia, SC

M. L. Skiles, University of South Carolina, Columbia, South Carolina

L. R. Rucker, University of South Carolina, Columbia, South Carolina

S. Sahai, University of South Carolina, Columbia, South Carolina