Con-current Oral Abstract Presentations Session 8

Enhancement of colloidal stability of cell signal-responsive gene carriers for disease cell-specific delivery

controlled release; drug delivery/release; gene therapy/gene delivery

Y. Katayama, Faculty of Engineering, Kyushu University, Fukuoka, Japan

S. Kushio, Kyushu University, Fukuoka, Japan

C. Kim, Kyushu University, Fukuoka, Japan

T. Niidome, Faculty of Engineering, Kyushu University, Fukuoka, Japan

T. Mori, Faculty of Engineering, Kyushu University, Fukuoka, Japan

Novel Solution of Nucleic Acid Delivery for in-vivo Diagnosis: Self-assembled Nanopieces

gene therapy/gene delivery; in vivo; nanoassembled devices

H. Yu, Warren Alpert Medical School, Brown University, Providence, RI

Design of Dendrimer-Based System for Delivery of Therapeutic SiRNA for Treating Cardiac Disease

cardiovascular; gene therapy/gene delivery; polymer

J. Liu, Georgia Institute of Technology, Atlanta, GA

C. Gu, Georgia Institution of Techonology, Atlanta, Georgia

B. Cabigas, Emory University, Atlanta, Hawaii

K. Pendergrass, Emory University, Atlanta, Georgia

M. Brown, Emory University, Atlanta, Georgia

Y. Luo, Peking University, Beijing, China

M. Davis, Georgia Institute of Technology and Emory University, Atlanta, Georgia

The Development of Safe and Effective Polymeric Carriers for SiRNA Delivery

gene therapy/gene delivery; polymer

A. R. Shrivats, Carnegie Mellon University, Pittsburgh, PA

E. Hsu, Carnegie Mellon University, Pittsburgh, Pennsylvania

A. Watt, Carnegie Mellon University, Pittsburgh, Pennsylvania

S. McBride, Carnegie Mellon University, Pittsburgh, Pennsylvania

S. Liu, Carnegie Mellon University, Pittsburgh, Pennsylvania

P. Alvarez-Urena, Carnegie Mellon University, Pittsburgh, Pennsylvania

S. Averick, Carnegie Mellon University, Pitsburgh, Pennsylvania

H. Cho, Carnegie Mellon University, Pittsburgh, Pennsylvania

E. Paredes, Carnegie Mellon University, Pittsburgh, Pennsylvania

S. R. Das, Carnegie Mellon University, Pittsburgh, Pennsylvania

K. Matyjaszewski, Carnegie Mellon University, Pittsburgh, Pennsylvania

J. O. Hollinger, Carnegie Mellon University, Pittsburgh, Pennsylvania

A Versatile Coiled-coil Tethering System for the Biofunctionalization of Recharged Gene Delivery Vectors

gene therapy/gene delivery; nanoassembled devices; surface modification

C. Fortier, Ecole Polytechnique de Montreal, Montreal, QC, Canada

B. Liberelle, Ecole Polytechnique de Montreal, Montreal, Québec, Canada

Y. Durocher, CNRC-NRC Montreal-Royalmount, Montreal, Québec, Canada

G. De Crescenzo, Ecole Polytechnique de Montreal, Montreal, Québec, Canada

Polysialic Acid-N-Trimethyl Chitosan Nanoparticles for Oligonucleotide Delivery

cell therapy; drug delivery/release; gene therapy/gene delivery

P. R. Wardwell, Syracuse University, Syracuse, NY

R. M. Iyer, Syracuse University, Syracuse, New York

P. N. Borer, Syracuse  University, Syracuse, New York

M. McPike, Aptamatrix, Syracuse, New York

M. B. Forstner, Syracuse University, Syracuse, New York

R. A. Bader, Syracuse University, Syracuse, New York

Targeted Delivery of micro-RNA by Ephrin-A1 Conjugated Nanoliposomal Particles (NLP) for Malignant pleural Mesothelioma

gene therapy/gene delivery

H. Lee, University of Florida, Gainesville, FL

MicroRNA 29a Inhibitor Loaded Gelatin Nanofibers for Localized Gene Therapy

nanotechnology

E. N. James, University of Connecticut Health Center, Middletown, CT

A. M. Delany, University of Connecticut Health Center, Farmington, Connecticut

L. S. Nair, University of Connecticut Health Center, Farmington, Connecticut

Peptide-grafted Poly(ethylene glycol) Hydrogels Support Endothelial Progenitor Cell Rolling and Adhesion Under Shear

cell adhesion; endothelialization; hydrogel

W. Seeto, Auburn University, Auburn, AL

Y. Tian, Polytechnic Institute of New York University, Auburn, Alabama

E. A. Lipke, Auburn University, Auburn, Alabama

A non-toxic additive to introduce X-ray contrast into poly(lactic acid). Implications for transient medical implants such as bioresorbable coronary vascular scaffolds

bioresorbable; polymer; stents

Y. Wang, Maastricht University, Maastricht, Netherlands

L. H. Koole, Maastricht University, Maastricht, Netherlands

MSCs Enhanced Endothelial Regeneration and Reduced Fibrosis on Bioengineered Vascular Graft

endothelial cells; stem/progenitor cells; vascular graft

W. Tan, University of Colorado, Boulder, CO

Small-Diameter Biodegradable Vascular Grafts Mechanical Characterization and Tissue Interactions

graft/copolymer; mechanical properties; vascular graft

A. Melchiorri, University of Maryland, College Park, MD

Z. R. Brandes, University of Maryland, College Park, Maryland

N. Hibino, Children's National Medical Center, District of Columbia, District of Columbia

J. P. Fisher, University of Maryland, College Park, Maryland

Degradable polar hydrophobic ionic polyurethane promotes endothelial and wound healing phenotype of circulating angiogenic cells

polyurethane(s); tissue engineering; vascular graft

E. S. Mathieu, University of Ottawa Heart Institute, Ottawa, ON, Canada

Aortic tissue-stent mechanical interaction in transcatheter aortic valve replacement

cardiovascular

J. Mummert, University of Connecticut, Storrs, CT

E. Sirois, University of Connecticut, Storrs, Connecticut

W. Sun, University of Connecticut, Storrs, Connecticut

Introducing a polymeric device for the treatment of Abdominal Aortic Aneurysms: Design and in vitro performance

polymer; vascular

D. Cohn, The Hebrew University of Jerusalem, Jerusalem, Israel

A. Bloom, Hadassah University Medical Center, Jerusalem, Israel

Reconfigurable Biodegradable Shape-memory Elastomers using “click” Chemistry

biodegradation; blood-material interaction; polymer

S. Ninh, Carnegie Mellon University, Pittsburgh, PA

C. Bettinger, Carnegie Mellon University, Pittsburgh, Pennsylvania

Non-Invasive Diagnosis of Intracerebral Hemorrhage Using Iodinated Liposomal Nanocarriers

nanomaterials/nanophase; nanotechnology

K. McNeeley, Georgia Institute of Technology, Atlanta, GA

K. McNeeley, Georgia Institute of Technology, Atlanta, Georgia

R. Bellamkonda, Georgia Institute of Technology, Atlanta, Georgia

Synthesis of Solid Lipid Nanoparticles and their Interaction with Skin

biosensors/biochips; lipid; nanotechnology

X. Calderon-Colon, The Johns Hopkins University Applied Physics Laboratory, Laurel, MD

M. W. Patchan, The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland

M. L. Theodore, The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland

H. T. Le, The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland

J. L. Sample, The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland

J. J. Benkoski, The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland

J. B. Patrone, The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland

Intracellular dynamics of oligopeptide-modified phospholipid polymer nanoparticles

nanomaterials/nanophase

K. ISHIHARA, The University of Tokyo, Tokyo, Japan

Surface Characterization of Functionalized Gold Nanoparticles

nanotechnology; surface characterization; surface modification

L. Gamble, University of Washington, Seattle, WA

A. Rafati, University of Washington, Seattle, Washington

S. D. Techane, University of Washington, Seattle, Washington

D. G. Castner, University of Washington, Seattle, Washington

Composite Biomaterials Active against Opportunistic Pathogens

antimicrobial; bioactive material; wound healing

M. D. Leonida, Fairleigh Dickinson University, Teaneck, NJ

A. Benzecry, Fairleigh Dickinson University, Teaneck, New Jersey

A. Suria, Fairleigh Dickinson University, Teaneck, New Jersey

Reduced Adhesion of Staphylococcus aureus to ZnO/PVC Nanocomposites

nanomedicine; nanomodified surfaces; nanotechnology

B. M. Geilich, Northeastern University, Brookline, MA

T. J. Webster, Northeastern University, Boston, Massachusetts

Cecropin-mellitin modified surfaces exhibit high antimicrobial activity and low cytotoxicity against human cells

antimicrobial; cytotoxicity; nanomodified surfaces

M. B. Evangelista, BIOCANT - Technology Transfer Association and CNC - Center for Neuroscience and Cell Biology, Cantanhede, Portugal

A. Rai, Biocant - Parque Tecnologico de Cantanhede and CNC - Center for Neuroscience and Cell Biology, Cantanhede, Portugal

M. B. Evangelista, Biocant - Parque de Tecnologico de Cantanhede and CNC - Center for Neuroscience and Cell Biology, Cantanhede, Portugal

S. Pinto, CNC - Center for Neuroscience and Cell Biology, Cantanhede, Portugal

L. S. Ferreira, Biocant - Parque Tecnologico de Cantanhede and CNC - Center for Neuroscience and Cell Biology, Cantanhede, Portugal

Multivalent Gd-DOTA Decorated Starlike Amphiphilic Dextran Micelles as Sensitive MRI Probes

graft/copolymer; nanomaterials/nanophase; nanomedicine

H. Ai, Sichuan University, Chengdu, China

H. Su, Sichuan University, Chengdu, China

D. Li, Sichuan University, Chengdu, China

C. Wu, Sichuan University, Chengdu, China

C. Xia, Sichuan University, Chengdu, China

Q. Gong, Sichuan University, Chengdu, China

B. Song, Sichuan University, Chengdu, China

The Efficacy of Vitamin E and a Hindered Amine Light Stabilizer in stabilizing UHMWPE from Oxidation

arthroplasty; polyethylene (UHMWPE); radiation

A. Bellare, Brigham & Women's Hospital, Harvard Medical School, Boston, MA

Collagen and Elastin Binding Polyphenols Protect Scaffolds and Stem Cells from Diabetes-Related Complications

inflammation; scaffolds; tissue engineering

J. P. Chow, Clemson University, Clemson, SC

Extraction Analysis of Vitamin E-Grafted Polyethylene

polyethylene (UHMWPE); polymer

S. Spiegelberg, Cambridge Polymer Group, Inc., Boston, MA

N. Turner, Cambridge Polymer Group, Boston, Massachusetts

T. Wilson-Hill, Cambridge Polymer Group, Boston, Massachusetts

D. Pletcher, Zimmer, Inc., Warsaw, Indiana

A. Rufner, Zimmer, Inc., Warsaw, Indiana

Antioxidant Cerium Oxide Nanoparticle Composite Hydrogels for Islet Encapsulation and Protection

bioactive material; diabetes; inflammation

J. D. Weaver, University of Miami, Miami, FL

C. L. Stabler, University of Miami, Miami, Florida

Reducing Lipid Absorption in Highly Crosslinked Grafted Vitamin E Polyethylene

bearing surfaces; polyethylene (UHMWPE); radiation

D. Pletcher, Zimmer, Inc, Warsaw, IN

A. Rufner, Zimmer, Inc, Warsaw, Indiana

Microparticulate Formulations of Antioxidant Poly(β-Amino Ester) Polymers for Wound Healing Applications

biodegradation; controlled release; wound healing

N. M. Shah, University of Kentucky, Lexington, KY

S. H. Deschamp, University of Kentucky, Lexington, Kentucky

J. Hilt, University of Kentucky, Lexington, Kentucky

T. D. Dziubla, University of Kentucky, Lexington, Kentucky

Development of new toxin-adsorbing and hemocompatible surfaces as a step towards a miniaturized artificial kidney

adsorption; coating(s); hemocompatibility

J. H. Janssen, Maastricht University and INterface BIOmaterials BV, Geleen, Netherlands

Development of a Catheter-Deployable Device for the Capture of Rare Analytes in Blood

blood-material interaction; sensor; surface modification

J. C. Sy, Massachusetts Institute of Technology, Cambridge, MA

J. Fernandez Esmerats, Massachusetts Institute of Technology, Cambridge, Massachusetts

A. E. Wisniowska, Massachusetts Institute of Technology, Cambridge, Massachusetts

J. M. Milwid, Massachusetts Institute of Technology, Cambridge, Massachusetts

M. J. Cima, Massachusetts Institute of Technology, Cambridge, Massachusetts

Bioactive coatings for vascular implants: a promising strategy using oriented tethering of EGF on chondroitin sulfate

bioactive material; surface modification; vascular

P. Lequoy, Ecole de Technologie Supérieure, Montreal, QC, Canada

B. Liberelle, Ecole Polytechnique de Montreal, Montreal, Québec, Canada

C. Fortier, Ecole Polytechnique de Montreal, Montreal, Québec, Canada

G. De Crescenzo, Ecole Polytechnique de Montreal, Montreal, Québec, Canada

S. Lerouge, Ecole de Technologie Superieure, Montreal, Québec, Canada

Development of Viral Nanoparticle Networks and Hybrids for Enhanced Tumor Homing and Penetration

drug delivery/release; nanotechnology

A. M. Wen, Case Western Reserve University, Cleveland, OH

N. F. Steinmetz, Case Western Reserve University, Cleveland, Ohio

Precisely Designed Thermo-responsive Polymer Brush Surface for Cell Separation

biomaterials availability; cell-material interactions; smart materials

K. Nagase, Tokyo Women's Medical University, Tokyo, Japan

A. Kimura, Waseda University, Tokyo, Japan

Y. Hatakeyama, Waseda University, Tokyo, Japan

T. Shimizu, Tokyo Women's Medical University, Tokyo, Japan

K. Matsuura, Tokyo Women's Medical University, Tokyo, Japan

M. Yamato, Tokyo Women's Medical University, Tokyo, Japan

N. Takeda, Waseda University, Tokyo, Japan

T. Okano, Tokyo Women's Medical University, Tokyo, Japan

Ultrathin Surface Coating of Thermoresponsive Block Copolymers for Fabricating Cell Sheets

cell adhesion; coating(s); smart materials

M. Nakayama, Tokyo Women's Medical University, Tokyo, Japan

Y. Kimura, Keio University, Tokyo, Japan

N. Yamada, Keio University, Tokyo, Japan

H. Kanazawa, Keio University, Tokyo, Japan

T. Okano, Tokyo Women’s Medical University, Tokyo, Japan

Robust Photolabile Physically Crosslinked Polymer Networks

block copolymer

C. Zhu, Carnegie Mellon University, Pittsburgh, PA

C. Bettinger, Carnegie Mellon University, Pittsburgh, Pennsylvania

Slippery When Wet: Gradient Surface Functionalization of Hydrogels for Lubricity Control

hydrogel; nanomodified surfaces; surface modification

B. A. Krick, University of Florida, Gainesville, FL

A. A. Pitenis, University of Florida, Gainesville, Florida

A. C. Dunn, University of Florida, Gainesville, Florida

W. Sawyer, University of Florida, Gainesville, Florida

Dose Response to TGF-β3 of Co-Cultured Chondrocytes and Mesenchymal Stem Cells on Porous Polymer Scaffolds

articular cartilage; stem/progenitor cells; tissue engineering

R. L. Dahlin, Rice University, Houston, TX

M. Ni, Rice University, Houston, Texas

V. V. Meretoja, Rice University, Houston, Texas

F. K. Kasper, Rice University, Houston, Texas

A. G. Mikos, Rice University, Houston, Texas

Heparin-containing Hydrogels for Sustained Release of Cathepsin Inhibitors for Treatment of Tendon Degeneration

animal model; drug delivery/release; hydrogel

S. P. Seto, Georgia Institute of Technology, Atlanta, GA

T. Miller, Georgia Institute of Technology, Atlanta, Georgia

Y. Qiu, Georgia Institute of Technology, Atlanta, Georgia

M. O. Platt, Georgia Institute of Technology, Atlanta, Georgia

J. S. Temenoff, Georgia Institute of Technology, Atlanta, Georgia

Effects of Ceramic Structural Properties on Chondrocyte Response

bioactive material; calcium phosphate(s); tissue engineering

M. K. Boushell, Columbia University, New York, NY

R. Z. LeGeros, New York University, New York, New York

H. H. Lu, Columbia University, New York, New York

Cartilage Tissue Engineering with Silk Fibroin Scaffolds Fabricated by Indirect Additive Manufacturing Technology

cartilage; scaffolds; tissue engineering

V. Shyu, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan, Tao-Yuan, Taiwan

Co-electrospun Scaffolds with Gradients in Fiber Alignment and Chemistry for the Regeneration of Ligament-Bone Transitions

biomimetic; stem/progenitor cells; tissue engineering

A. R. Whittington, Virginia Polytechnic Institute and State University, Blacksburg, VA

S. Samavedi, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

P. Gaddam, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

A. R. Whittington, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

A. S. Goldstein, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

Micropatterned co-cultures of endothelial cells and mesenchymal stem cells within gelatin methacrylate hydrogels

cardiovascular; endothelial cells; hydrogel

M. Nikkhah, Harvard Medical School, Cambridge, MA

Electrospun Bilayered Vascular Scaffolds for Engineering Small Diameter Blood Vessels

cardiovascular; tissue engineering; vascular graft

S. Lee, Wake Forest School of Medicine, Winston-Salem, NC

Novel Bioactive Coatings to Improve Allograft Incorporation Evaluated in eGFP Chimeric Rats

bone; sustained release; tissue engineering

A. Das, University of Virginia, Charlottesville, VA

Y. Lin, University of Virginia, Charlottesville, Virginia

Q. Cui, University of Virginia, Charlottesville, Virginia

E. Botchwey, Gatech, Atlanta, Georgia

Adverse Tissue Response to Corrosion and Products of Corrosion in CoCr Dual-Modular Neck Hip Prostheses

corrosion; hip prosthesis; implant retrieval

D. J. Hall, Rush University Medical Center, Chicago, IL

R. M. Urban, Rush University Medical Center, Chicago, Illinois

H. J. Cooper, Rush University Medical Center, Chicago, Illinois

J. L. Wright, Rush University Medical Center, Chicago, Illinois

E. L. Dahlmeier, Rush University Medical Center, Chicago, Illinois

J. J. Jacobs, Rush University Medical Center, Chicago, Illinois

Prediction of Voltage Shifts During Fretting Corrosion of Titanium Alloy: Effect of Area, Impedance and Mechanics

corrosion; titanium (alloys); tribology

Y. Liu, Biomedical and Chemical Engineering Department, Syracuse Biomaterials Institute, Syracuse University, Syracuse, NY,, Syracuse, NY

S. Mali, Biomedical and Chemical Engineering Department, Syracuse Biomaterials Institute,Syracuse University, Syracuse, New York

J. Gilbert, Biomedical and Chemical Engineering Department, Syracuse Biomaterials Institution,Syracuse University, Syracuse, New York

Wear-corrosion Synergism under Fretting and Sliding Contacts in Hip Prosthesis

corrosion; fretting; total joint replacement

M. T. Mathew, Rush University Medical Center, Chicago, IL

Study of bio-tribocorrosion behavior of Ti6Al4V alloys colonized with osteoblastic-like cells for metal hip prosthesis

biodegradation; cell culture; titanium (alloys)

M. J. C. Runa, University of Minho, Guimarães, Portugal

M. H. R. Fernandes, University of Porto, Faculty of Dental Medicine, Porto, Portugal

M. M. T. Mathew, Rush University Medical Center, Chicago, Illinois

L. A. S. Rocha, University of Minho, Guimaraes, Portugal

Fretting Corrosion Performance Test of Spinal Screw and Rod Constructs: Effect of Stainless Steel –Titanium Combination

corrosion; fretting

S. A. MALI, SYRACUSE UNIVERSITY, Syracuse, NY

Tribocorrosion Behavior of Anodic Titanium Oxide Films and Assessment of Cell-Materials Interactions

cell-material interactions; corrosion; surface modification

S. A. Alves, University of Minho, Guimaraes, Portugal

R. Bayón, Fundación IK4-Tekniker, Eibar, Spain

V. S. de Viteri, Fundación IK4-Tekniker, Eibar, Spain

M. P. Garcia, Faculty of Dental Medicine of Porto University, Porto, Portugal

A. Igartua, Fundación IK4-Tekniker, Eibar, Spain

M. H. Fernandes, Faculty of Dental Medicine of Porto University, Porto, Portugal

L. A. Rocha, University of Minho, Guimaraes, Portugal

Quartz crystal mass monitoring to study tribofilm formation and retention in self-mating CoCrMo systems

cobalt-chromium (alloys); corrosion; tribology

R. Pourzal, Rush University Medical Center, Chicago, IL

Hydroxyapatite Coated Porous Magnesium with for Biomedical Applications

biodegradation; coating(s); porosity

M. Kang, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea