Con-current Oral Abstract Presentations Session 3

Biomaterials Microenvironment for Stem Cells and Tissue Regeneration I

79

Mesenchymal Stem Cell and Gelatin Microparticle Encapsulation in Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering

S. N. Tzouanas, Rice University, Houston, TX

A. K. Ekenseair, Northeastern University, Boston, MA

K. Kasper, Rice University, Houston, TX

A. G. Mikos, Rice University, Houston, TX

80

In Situ Cross-linkable Gelatin Hydrogels for Vasculogenic Delivery of Mesenchymal Stem Cells

S. Lee, Vanderbilt University, Nashville, TN

Y. Chun, Vanderbilt University, Nashville, TN

Y. Lee, Ajou University, Suwon, Korea, Republic of

D. Deskins, Vanderbilt University Medical Center, Nashville, TN

P. Young, Vanderbilt University Medical Center, Nashville, TN

K. Park, Ajou University, Suwon, Korea, Republic of

H. Sung, Vanderbilt University, Nashville, TN

81

Identifying targets for peptide-based osteogenic induction for osteochondral tissue engineering

A. H. Aziz, University of Colorado at Boulder, Boulder, CO

S. J. Bryant, University of Colorado at Boulder, Boulder, CO

82

Design and Surface-Modification of Poly(Propylene Fumarate) Scaffolds for Mesenchymal Stem Cell Attachment and Differentiation

K. M. Ferlin, University of Maryland - College Park, College Park, MD

M. E. Prendergast, University of Maryland - College Park, College Park, MD

M. L. Miller, University of Maryland - College Park, College Park, MD

D. S. Kaplan, Food and Drug Administration, Silver Spring, MD

J. P. Fisher, University of Maryland - College Park, College Park, MD

83

Micropatterned films of conducting polymers with entrapped biomolecules for neuronal cell adhesion

S. Park, Pennsylvania State University, University Park, PA

D. R. Nocera, Pennsylvania State University, University Park, PA

M. R. Abidian, Pennsylvania State University, University Park, PA

S. Majd, Pennsylvania State University, University Park, PA

84

Reversible and irreversible activations of YAP/TAZ in hMSCs on phototunable hydrogels

C. Yang, BioFrontiers Institute, University of Colorado Boulder, Boulder, CO

M. W. Tibbitt, BioFrontiers Institute, University of Colorado Boulder, Boulder, CO

L. Basta, University of Colorado, Boulder, CO

K. S. Anseth, Howard Hughes Medical Institute, BioFrontiers Institute, University of Colorado Boulder, Boulder, CO

Engineering Stimuli-Responsive Cues into Biomaterials

85

Nanoparticles for targeted, pH-responsive delivery of anti-biofilm drugs

B. Horev, University of Rochester, Rochester, NY

D. Benoit, University of Rochester, Rochester, NY

H. Koo, University of Pennsylvania, Philadelphia, PA

M. Klein, University of Rochester, Rochester, NY

86

Flexible control over the rate and timing of drug delivery from magnetically responsive hydrogels

S. Kennedy, Harvard University, Cambridge, MA

P. Spoerri, Harvard University, Cambridge, MA

A. Deleris, Harvard University, Cambridge, MA

C. Cezar, Harvard University, Cambridge, MA

P. Hedrick, Harvard University, Cambridge, MA

D. Mooney, Harvard University, Cambridge, MA

87

Tuning of Stiffness Anisotropy in Collagen Sheets by Planar Stretch

A. Islam, Case Western Reserve University, Cleveland, OH

S. Cotey, Case Western Reserve University, Cleveland, OH

M. Younesi, Case Western Reserve University, Cleveland, OH

O. Akkus, Case Western Reserve University, Cleveland, OH

88

Hybrid Photopatterned Enzymatic Reaction (HyPER) for in Situ Cell Manipulation

T. Segura, University of California, Los Angeles, Los Angeles, CA

89

Polypeptide-Gold Nanorod Solders for Laser Tissue Repair

J. M. Ramos, Arizona State University, Tempe, AZ

H. Huang, Massachusetts General Hospital and Harvard Medical School, Boston, MA

K. Subramaniam, Arizona State University, Tempe, AZ

K. Rege, Arizona State University, Tempe, AZ

90

Characterization of a Fluorescent Liposome-Based Multiplexing Biosensor System

C. J. Wright, Furman University, Greenville, SC

M. A. Evans, Furman University, Greenville, SC

D. E. Ebzery, Furman University, Greenville, SC

C. E. Hansen, Furman University, Greenville, SC

T. W. Hanks, Furman University, Greenville, SC

91

Functionalization of hydrogels with a matrix metalloproteinase-sensitive fluorogenic substrate to measure cellular response to drug treatment

J. L. Leight, University of Colorado/HHMI, Boulder, CO

E. Y. Tokuda, University of Colorado, Boulder, CO

K. S. Anseth, University of Colorado/HHMI, Boulder, CO

92

Cytocompatible Covalently Adaptable Networks to Probe Biophysical Behavior of Encapsulated Cells

D. D. McKinnon, University of Colorado, Boulder, CO

D. W. Domaille, University of Colorado, Boulder, CO

B. Sridhar, University of Colorado, Boulder, CO

K. A. Kyburz, University of Colorado, Boulder, CO

J. N. Cha, University of Colorado, Boulder, CO

K. S. Anseth, University of Colorado/HHMI, Boulder, CO

Mechanobiology for Biomaterials Design

93

Beyond Elastic Modulus: The Role of Interfacial Mechanics in Cell Behavior

M. A. Calhoun, The Ohio State University, Columbus, OH

S. Rao, The Ohio State University, Columbus, OH

S. Bentil, The Ohio State University, Columbus, OH

A. Short, The Ohio State University, Columbuso, OH

T. Nelson, The Ohio State University, Columbus, OH

A. Sarkar, Geisinger Healthcare Systems, Danville, PA

J. Lannutti, The Ohio State University, Columbus, OH

R. Dupaix, The Ohio State University, Columbus, OH

J. O. Winter, The Ohio State University, Columbus, OH

94

Hydrogels with Differential and Patterned Mechanics to Study Stiffness-Mediated Myofibroblastic Differentiation of Hepatic Stellate Cells

M. Guvendiren, University of Pennsylvania, Philadelphia, PA

S. Caliari, University of Pennsylvania, Philadelphia, PA

M. Perepelyuk, University of Pennsylvania, Philadelphia, PA

R. G. Wells, University of Pennsylvania, Philadelphia, PA

J. A. Burdick, University of Pennsylvania, Philadelphia, PA

95

Matrix Elasticity Regulates Melanoma Cell Survival

E. Y. Tokuda, University of Colorado, Boulder, CO

J. L. Leight, University of Colorado/HHMI, Boulder, CO

K. S. Anseth, University of Colorado/HHMI, Boulder, CO

96

Valvular Interstitial Cell Response to Elasticity in Three-Dimensional Microenvironments

K. M. Mabry, University of Colorado at Boulder, Boulder, CO

K. S. Anseth, University of Colorado/HHMI, Boulder, CO

98

Fibronectin and Type I Collagen Dysregulations Drive Tumor Progression

K. C. Wang, Cornell University, Ithaca, NY

V. Benson, Cornell University, Ithaca, NY

M. Quien, Cornell Univerisity, Ithaca, NY

L. Hsu, Cornell University, Ithaca, NY

C. Fischbach, Cornell University, Ithaca, NY

D. Gourdon, Cornell University, Ithaca, NY

99

The Application of Decellularized Tendon Biomaterial and RNA-Interference to Study Integrin-mediated Mechanotransduction in Tenocytes

C. Schnatwinkel, University of Colorado at Boulder, Boulder, CO

S. J. Bryant, University of Colorado at Boulder, Boulder, CO

100

Mechano-sensing of laterally mobile viscoelastic films induced biphasic cell spreading response

A. Kourouklis, University of Massachusetts-Amherst, Amherst, MA

H. Bermudez, University of Massachusetts-Amherst, Amherst, MA

Nanostructured Biomaterial Surfaces for Cellular and Tissue Engineering

101

Transitioning from Nanomedicine to Picomedicine: What’s on the Horizon ?

T. J. Webster, Northeastern, Boston, MA

102

Advanced Antibacterial Wound Dressing Produced with Natural-origin Materials

N. Monteiro, 3B´s Research Group – Biomaterials, Biodegradables and Biomimetics; Department of Polymer Engineering, University of Minho, Guimarães, Portugal

M. Martins, 3B´s Research Group – Biomaterials, Biodegradables and Biomimetics; Department of Polymer Engineering, University of Minho, Guimarães, Portugal

A. Martins, 3B´s Research Group – Biomaterials, Biodegradables and Biomimetics; Department of Polymer Engineering, University of Minho, Guimarães, Portugal

N. Fonseca, Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal

J. Moreira, Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal

R. Reis, University of Minho - 3B's Research Group, Guimarães, Portugal

N. Neves, 3B´s Research Group – Biomaterials, Biodegradables and Biomimetics; Department of Polymer Engineering, University of Minho, Guimarães, Portugal

103

Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells

A. K. Gaharwar, Texas A&M University, College Station, TX

S. M. Mihaila, Harvard medical School, Boston, MA

A. Swami, Harvard medical School, Boston, MA

A. Patel, Harvard medical School, Boston, MA

S. Sant, Harvard Medical School, Boston, MA

R. L. Reis, University of Minho, Guimarães, Portugal

A. P. Marques, University of Minho, Guimarães, Portugal

M. E. Gomes, University of Minho, Guimarães, Portugal

A. Khademhosseini, Harvard medical School, Boston, MA

104

Drug-Loaded Nanoparticles Induce Gene Expression In Human Pluripotent Stem Cell Derivatives

T. Harkness, University of Wisconsin-Madison, Madison, WI

V. Gajbhiye, University of Wisconsin-Madison, Madison, WI

L. Escalante, University of Wisconsin-Madison, Madison, WI

G. Chen, University of Wisconsin-Madison, Madison, WI

A. Laperle, University of Wisconsin-Madison, Madison, WI

Q. Zheng, University of Wisconsin-Madison, Madison, WI

B. Steyer, University of Wisconsin-Madison, Madison, WI

S. Gong, University of Wisconsin-Madison, Madison, WI

K. Saha, University of Wisconsin-Madison, Madison, WI

105

Covalent layer-by-layer Antioxidant Films for Cellular Encapsulation

M. Valdes, University of Miami, Miami, FL

K. M. Gattas-Asfura, University of Miami, Miami, FL

J. D. Weaver, University of Miami, Miami, FL

C. L. Stabler, University of Miami, Miami, FL

106

Effects of polycaprolactone nanowire surfaces on adipogenic and chondrogenic differentiation of adipose-derived stem cells

N. A. Trujillo, Colorado State University, Fort Collins, CO

K. C. Popat, Colorado State University, Fort Collins, CO

108

Imprinted nanotextured scaffolds for cell guiding and migration

M. Su, Worcester Polytechnic Institute, Worcester, MA

Sustainable Approaches to Biomaterials for Drug Delivery

109

Reactive Oxygen Species Degradable Thermo-Responsive Hydrogels for In Situ Drug Delivery to Cell Therapies

M. K. Gupta, Vanderbilt University, Nashville, TN

J. R. Martin, Vanderbilt University, Nashville, TN

T. Shen, Vanderbilt University, Nashville, TN

C. L. Duvall, Vanderbilt University, Nashville, TN

110

Multivalent Manganese Complexes Decorated Amphiphilic Dextran Micelles as Sensitive MRI Probes

C. Wu, National Engineering Research Center for Biomaterials, Sichuan University, PR China,

D. Li, National Engineering Research Center for Biomaterials, Sichuan University, PR China,

B. Lin, National Engineering Research Center for Biomaterials, Sichuan University, PR China,

C. Xia, Department of Radiology, West China Hospital, Sichuan University, PR China,

Q. Gong, Department of Radiology, West China Hospital, Sichuan University, PR China,

B. Song, Department of Radiology, West China Hospital, Sichuan University, PR China,

H. Ai, National Engineering Research Center for Biomaterials, Sichuan University, PR China,

111

Lipid-Enveloped Polymeric Nanoparticles For Delivery of Hydrophobic Drug

C. Kuo, Penn State University, University Park, PA

A. Leber, Penn State University, University Park, PA

S. Majd, Penn State University, University Park, PA

112

Tracking and Unraveling the Mechanism of Nanostructured Porous Si Carriers Erosion in Neoplastic State

A. Tzur-Balter, Technion – Israel Institute of Technology, Haifa, Israel

M. Beckerman, Massachusetts Institute of Technology, Cambridge, MA

Z. Shatsberg, Massachusetts Institute of Technology, Cambridge, MA

E. Segal, Technion – Israel Institute of Technology, Haifa, Israel

N. Artzi, Massachusetts Institute of Technology, Cambridge, MA

113

Sustained Release Behavior of Drug-Loaded Calcium Phosphate Microspheres

J. Baek, Seoul National University, Seoul, Korea, Republic of

H. Jung, Seoul National University, Seoul, Korea, Republic of

T. Jang, Seoul National University, Seoul, Korea, Republic of

S. Kim, Seoul National University, Seoul, Korea, Republic of

M. Kang, Seoul National University, Seoul, Korea, Republic of

J. Song, Seoul National University, Seoul, Korea, Republic of

H. Kim, Seoul National University, Seoul, Korea, Republic of

114

Design of Drug Delivery Nanoparticles Using 3D-Human Vascular Wall Models for Atherosclerosis Treatment

P. Chetprayoon, Osaka University, Osaka, Japan

M. Akashi, Osaka University, Osaka, Japan

115

Effects of Ascorbic Acid on Available Ferrous Iron from the Non-Hormonal Contraceptive Ovaprene® Ring

M. A. Vaughn, Poly-Med, Inc., Anderson, SC

K. J. Garcia, Poly-Med, Inc., Anderson, SC

G. T. Hilas, Poly-Med, Inc., Anderson, SC

J. T. Corbett, Poly-Med, Inc., Anderson, SC

116

An injectable and settable cell delivery system for tissue repair derived from in situ chemical polymerization

R. Guo, Vanderbilt University, Nashville, TN

C. Ward, National Research Council, United States Army Institute of Surgical Research, Houston, TX

J. Wenke, National Research Council, United States Army Institute of Surgical Research, Houston, TX

S. Guelcher, Vanderbilt University, Nashville, TN