Con-current Oral Abstract Presentations Session 6

Absorbable Polymers for Medical Devices: Current Status and Future Perspectives

209

In Vitro Degradation of 3D Printed Poly(Propylene Fumarate) Scaffolds

M. O. Wang, University of Maryland College Park, College Park, MD

C. Piard, Les Arts et Métier (ENSAM), à Paris Tech, College Park, MD

M. L. Dreher, Food and Drug Administration, Silver Spring, MD

A. Melchiorri, University of Maryland, College Park, MD

J. P. Fisher, University of Maryland, College Park, MD

210

PLGA Microsphere Spray System for Wound Coverage

Y. Zou, University of Kentucky, Lexington, KY

T. Milbrandt, University of Kentucky, Lexington, KY

D. Puleo, University of Kentucky, Lexington, KY

211

Thin, elastic polymer films for preventing unwanted soft tissue attachments

S. Mayes, Alafair Biosciences, Austin, TX

212

Visible light cured thiol-acrylate hydrogels with tunable degradation for controlled protein delivery

Y. Hao, Indiana University-Purdue University at Indianapolis, Indianapolis, IN

C. Lin, Indian University-Purdue University at Indianapolis, Indianapolis, IN

213

Absorbable, Injectable, Thermogelling Hydrogels of PCL-g-PEG

B. J. Tarasevich, Pacific Northwest National Laboratory, Richland, WA

L. Cosimbescu, Pacific Northwest Laboratory, Richland, WA

G. Lin, WSP Chemicals and Technology LLC, Leetsdale, PA

R. Jacob, Pacific Northwest National Laboratory, Richland, WA

214

Biodegradable Photoluminescent Polylactide and Polylacide-co-glycolide

Z. Xie, Pennsylvania State University, University Park, PA

J. Hu, South China University of Technology, Guangzhou, China

Q. Cai, Beijing University of Chemical Technology, Beijing, China

J. Yang, Pennsylvania State University, University Park, PA

215

Design of Experiments Approach to Identify Dominant Formulation Factors for Vancomycin-Loaded PLGA Microspheres

D. Puleo, University of Kentucky, Lexington, KY

216

In Vitro Degradation of Poly(p-dioxanone) Fibers: Effects of Size, Temperature and pH

E. Vailhe, Ethicon, a Johnson & Johnson Company, Somerville, NJ

M. Deng, Ethicon, a Johnson & Johnson Company, Somerville, NJ

D. Burkley, Ethicon, a Johnson & Johnson Company, Somerville, NJ

Y. Xu, Ethicon, a Johnson & Johnson Company, Somerville, NJ

L. Vailhe, Ethicon, a Johnson & Johnson Company, Somerville, NJ

V. Zhou, Ethicon, a Johnson & Johnson Company, Somerville, NJ

Advances in Programmable Biomaterials

217

Novel phase transition peptide polymers with LCST and UCST behavior

F. García Quiroz, Duke University, Durham, NC

A. Chilkoti, Duke University, Durham, NC

218

Shear-Thinning Hydrogels with Secondary Michael-type Crosslinking to Modulate Properties In Situ

C. B. Rodell, University of Pennsylvania, Philadelphia, PA

S. M. Dorsey, University of Pennsylvania, Philadelphia, PA

W. M. Gramlich, University of Pennsylvania, Philadelphia, PA

J. A. Burdick, University of Pennsylvania, Philadelphia, PA

219

Reversibly Stiffening Hydrogels to Probe Myofibroblast Activation

A. M. Rosales, University of Colorado/HHMI, Boulder, CO

E. M. Nehls, University of Colorado, Boulder, CO

K. S. Anseth, University of Colorado/HHMI, Boulder, CO

220

Sequential and Site-Specific Delivery of Dual Anticancer Therapeutics Using Programmed Nanodepots

T. Jiang, North Carolina State University, Raleigh, NC

222

Functionalized Gellan Gum Hydrogels Potentiate Endothelial Cell Performance

L. P. da Silva, 3B’s Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal; ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal; Department of Bioengineering, University of California at Berkeley, Be,

223

Designing Cell-Mediated Degrading PEG Hydrogels for Personalizing Cartilage Tissue Engineering

S. C. Skaalure, University of Colorado Boulder, Boulder, CO

S. J. Bryant, University of Colorado Boulder, Boulder, CO

224

Programmable Hydrogels for Drug Delivery and Regenerative Medicine

Y. Wang, The Pennsylvania State University, University Park, PA

Biologically Derived Materials from Natural Resources I

226

Naturally Occurring Nanoparticles from Fungi for Tumor Immunochemotherapy

Y. Wang, The Ohio State University, Columbus, OH

S. Yi, The University of Tennessee, Knoxville, TN

L. Sun, The University of Tennessee, Knoxville, TN

Y. Huang, The University of Tennessee, Knoxville, TN

M. Zhang, The Ohio State University, Columbus, OH

227

Comparison of different decellularization methods on adipose tissue: the advantage of physical method

S. S. Shanbhag, Nanyang Technological University, Singapore, Singapore

B. Luo, Nanyang Technological University, Singapore, Singapore

S. Foo, Nanyang Technological University, Singapore, Singapore

N. Tan, Nanyang Technological University, Singapore, Singapore

M. T. C. Wong, Tan Tock Seng Hospital, Singapore, Singapore

C. Choong, Nanyang technological University, Singapore, Singapore

228

Porous Silk Fibroin Hydrogels with Tunable Stiffness for Vascular Tissue Engineering

M. Floren, University of Colorado Boulder, Boulder, CO

W. Bonani, University of Trento, Boulder, CO

N. Tseng, University of Colorado Denver, Denver, CO

C. Migliaresi, University of Trento, Boulder, CO

W. Tan, University of Colorado Boulder, Boulder, CO

229

A Crucial Process: Organic Matrix and Magnesium Ion Control Amorphous Calcium Carbonate Crystallization on ß-Chitin Film

Y. Ma, Tsinghua University, Beijing, China

Q. Feng, Tsinghua University, Beijing, China

230

Synthesis and characterization of new pectin derivative with antitumor property

E. A. M. S. ALMEIDA, UNIVERSIDADE ESTADUAL DE MARINGA, Maringa, Brazil

A. F. MARTINS, UNIVERSIDADE ESTADUAL DE MARINGA, Maringa, Brazil

C. V. NAKAMURA, UNIVERSIDADE ESTADUAL DE MARINGA, Maringa, Brazil

A. F. RUBIRA, UNIVERSIDADE ESTADUAL DE MARINGA, Maringa, Brazil

E. C. MUNIZ, UNIVERSIDADE ESTADUAL DE MARINGA, Maringa, Brazil

231

Development of multifunctional platelet lysate membranes for tissue engineering applications

P. S. Babo, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

V. E. Santo, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

R. L. Pires, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

A. C. Duarte, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

C. Correia, iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal

M. H. G. Costa, MIT Portugal Program, Bioengineering Systems, Lisboa, Portugal

J. F. Mano, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

R. L. Reis, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

M. E. Gomes, 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Taipas, Guimarães, Portugal

Cardiovascular Biomaterials and Blood Compatibility I

233

S-Nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon Catheters Reduce Thrombosis and Bacterial Adhesion

E. J. Brisbois, University of Michigan, Ann Arbor, MI

H. Handa, University of Michigan, Ann Arbor, MI

R. Davis, University of Michigan, Ann Arbor, MI

A. Jones, University of Michigan, Ann Arbor, MI

R. Bartlett, University of Michigan, Ann Arbor, MI

M. E. Meyerhoff, University of Michigan, Ann Arbor, MI

234

Antioxidant citric-acid based polymers inhibit intimal hyperplasia

R. van Lith, Northwestern University, Evanston, IL

E. Gregory, Northwestern University, Chicago, IL

M. Kibbe, Northwestern University, Chicago, IL

G. Ameer, Northwestern University, Evanston, IL

235

Novel TRI™ Heart Valve Biomaterial Resists Calcification and Structural Degradation In-vivo

H. Tam, Clemson University, Clemson, SC

W. Zhang, University of Austin, Texas, Austin, TX

K. Feaver, University of Austin, Texas, Austin, TX

M. Sacks, University of Austin, Texas, Austin, TX

N. Vyavahare, Clemson University, Clemson, SC

236

Development of a Small Caliber Vascular Graft with Decellularized Arteries

B. Jiang, Northwestern University, Evanston, IL

B. Akgun, Northwestern University, Chicago, IL

R. Lam, Northwestern University, Evanston, IL

G. Ameer, Northwestern University, Evanston, IL

J. Wertheim, Northwestern University, Chicago, IL

237

Fabrication and evaluation of elastomeric hollow fiber membranes as small diameter vascular graft substitutes

A. E. Mercado-Pagan, Stanford University, Stanford, CA

Y. Kang, Stanford University, Stanford, CA

M. W. Findlay, Stanford University, Stanford, CA

G. C. Gurtner, Stanford University, Stanford, CA

Y. Yang, Stanford University, Stanford, CA

238

Non-covalent Surface Modification of Erythrocytes: Study of Binding Strength and Effect on Membrane Integrity

S. G. Pandya, University of Texas at San Antonio, San Antonio, TX

C. M. Agrawal, University of Texas at San Antonio, San Antonio, TX

Ceramics and Composites in Bone Tissue Engineering and Drug Delivery III

239

Space Maintenance and New Bone Formation with Polyurethane Biocomposites in a Canine Saddle Defect

A. D. Talley, Vanderbilt University, Nashvile, TN

K. A. Kalpaci, Medtronic, Inc, Memphis, TN

K. J. Zienkiewicz, Vanderbilt University, Nashville, TN

J. C. Wenke, US Army Institute of Surgical Research, Fort Sam Houston, TX

S. A. Guelcher, Vanderbilt University, Nashville, TN

240

Collagen Films on Hydroxyapatite Scaffolds Enhance rhBMP-2 Based Regeneration in Large Bone Defects

T. Guda, University of Texas at San Antonio, San Antonio, TX

S. M. Shiels, US Army Institute of Surgical Research, Ft Sam Houston, TX

S. Karajgar, University of Texas at San Antonio, San Antonio, TX

M. R. Appleford, University of Texas at San Antonio, San Antonio, TX

J. C. Wenke, US Army Institute of Surgical Research, Ft. Sam Houston, TX

J. L. Ong, University of Texas at San Antonio, San Antonio, TX

242

Fabrication of High Strength Calcium Phosphate Scaffolds for Bone Repair Using Naturally Derived Silk Material

S. L. McNamara, Tufts University, Medford, MA

T. Lo, Tufts University, Medford, MA

J. Rnjak-Kovacina, Tufts University, Medford, MA

D. Kaplan, Tufts University, Medford, MA

243

Tuning the Degradation Rate of Calcium Phosphate Cement via Addition of PLGA Porogen Content to Accelerate Bone Regeneration

C. I. van Houdt, Radboud University Medical Centre, Nijmegen, Netherlands

R. S. Preethanath, King Saud University, Riyadh, Saudi Arabia

B. A. van Oirschot, Radboud University Medical Centre, Nijmegen, Netherlands

J. A. Jansen, Radboud University Medical Centre, Nijmegen, Netherlands

J. J. van den Beucken, Radboud University Medical Centre, Nijmegen, Netherlands

244

Characterization and Release Kinetics of Calcium Silicate Cement as a Risedronate Delivery System

T. Gong, the University of British Columbia,

Y. Zhang, Shenyang Agriculture University, Shenyang, China

Z. Wang, Safety Evaluation Center of Shenyang Research Institute of Chemical Industry Ltd, Shenyang, China

C. Chen, Safety Evaluation Center of Shenyang Research Institute of Chemical Industry Ltd, Shenyang, China

Y. Zhang, Rescue Center of Severe Wound and Trauma of Chinese PLA, Shenyang, China

X. Yang, Shanghai CP Guojian Pharmaceutical Co. Ltd.,, Shanghai, China

X. Liu, General Hospital of Shenyang Military Area Command of Chinese PLA, Shenyang, China

Y. Wang, General Hospital of Shenyang Military Area Command of Chinese PLA, Shenyang, China

T. Troczynski, the University of British Columbia,

Q. Yang, the University of British Columbia,

U. O. Häfeli, the University of British Columbia,

245

Adsorption and Desorption of FGF-2 from Carbonate Apatite Granular

K. Ishikawa, Kyushu University, Fukuoka, Japan

T. Yoshida, Kyushu University, Fukuoka, Japan

R. Toita, Kyushu University, Fukuoka, Japan

K. Tsuru, Kyushu University, Fukuoka, Japan

246

I-Optimal Design and Topology Control of 3D Scaffolds Produced by Fused Deposition Modeling

A. M. Yousefi, Miami University, Oxford, OH

C. A. Focke, Miami University, Oxford, OH

C. S. Janney, Miami University, Oxford, OH

A. J. Naber, Miami University, Oxford, OH

K. Reichenbach, Miami University, Oxford, OH

C. Shaw, Miami University, Oxford, OH

S. E. Szekely, Miami University, Oxford, OH

L. P. Taylor, Miami University, Oxford, OH

B. Smucker, Miami University, Oxford, OH

Effect of Scaffold Properties on 3D Cell Shape

248

Microenvironment Dimensionality and Cells of the Nervous System: Significant Effects on Cell Shape and Signaling

S. Balasubramanian, UMBC, Baltimore, MD

H. Gaifem, UMBC, Baltimore, MD

J. B. Leach, UMBC, Baltimore, MD

249

Collagen-Matrix Guided Vasculogenesis: Cell Shape and Cytomechanics Drive Vessel Morphogenesis

S. L. Voytik-Harbin, Purdue University, West Lafayette, IN

T. Kim, Purdue University, West Lafayette, IN

C. F. Whittington, Purdue University, West Lafayette, IN

P. Critser, Indiana University School of Medicine, Indianapolis, IN

K. Buno, Purdue University, West Lafayette, IN

M. Yoder, Indiana University School of Medicine, Indianapolis, IN

250

Harnessing Cell:Materials Interactions to Develop Innovative Strategy for the Recruitment of Progenitor Cells

L. Indolfi, Massachusetts Institute of Technology, Cambridge, MA

C. Iaconetti, Magna Graecia University, Catanzaro, Italy

###A. Monteforte, University of Texas at Austin,

###A. Dunn, University of Texas at Austin,

###A. Baker, University of Texas at Austin,

C. Indolfi, Magna Graecia University, Catanzaro, Italy

E. Edelman, Massachusetts Institute of Technology, Cambridge, MA

251

Machine Learning Analysis for Identification of Cell Shape Metrics Associated with Stem Cell Differentiation in Nanofiber Scaffolds

D. Chen, University of Maryland, College Park, College Park, MD

S. Sarkar, National Institute of Standards and Technology, Gaithersburg, MD

J. Candia, University of Maryland, College Park, College Park, MD

S. J. Florczyk, National Institute of Standards and Technology, Gaithersburg, MD

S. Bodhak, National Institute of Standards and Technology, Gaithersburg, MD

M. K. Driscoll, University of Maryland, College Park, College Park, MD

C. G. Simon, Jr., National Institute of Standards and Technology, Gaithersburg, MD

J. P. Dunkers, National Institute of Standards and Technology, Gaithersburg, MD

W. Losert, University of Maryland, College Park, College Park, MD

252

Substrate Stiffness Affects Cell Responsiveness to Cytotoxic Compounds

S. P. Zustiak, Saint Louis University, St Louis, MO

K. Kalinowski, Saint Louis University, St Louis, MO

J. Schober, Southern Illinois University Edwardsville, Edwardsville, IL

K. Ramamoorthi, Santa Clara University, Santa Clara, CA

P. Asuri, Santa Clara University, Santa Clara, CA

253

Harnessing the Relaxation of Fibrin-microgel Assemblies for Control of Cell Spreading and Motility

A. M. Douglas, Georgia Institute of Technology, Atlanta, GA

B. Menn, Georgia Institute of Technology, Atlanta, GA

J. S. Hyatt, Georgia Institute of Technology, Atlanta, GA

A. Fernandez-Nieves, Georgia Institute of Technology, Atlanta, GA

L. A. Lyon, Georgia Institute of Technology, Atlanta, GA

T. H. Barker, Georgia Institute of Technology, Atlanta, GA

Trends in Surface Modification of Bulk- and Nano-Biomaterials II

107

Protein Adsorption and Affects on Platelet Adhesion and Bacterial Adhesion on Submicron Textured Biomaterial Surfaces

K. Yoshie, The University of Tokyo, Tokyo, Japan

Y. Inoue, The University of Tokyo, Tokyo, Japan

K. Ishihara, The University of Tokyo, Tokyo, Japan

254

Use of Ce Valence States in Cerium Oxide Nanoparticles to Control Cell Proliferation on Scaffold Surfaces

T. Naganuma, National Institute for Materials Science (NIMS), Tsukuba, Japan

255

MgF2 Coating on Porous Magnesium with High Strength and Corrosion Resistance for Biomedical Application

H. Jung, Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

M. Kang, Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

H. Kim, Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

Y. Estrin, Centre for Advanced Hybrid Materials, Department of Materials Engineering, Monash University, Clayton, Australia

256

Polymeric Nanostructure Layer-by-Layer Networks: Structural and Bio-functional relevance as Synthetic Mucus

S. P. Authimoolam, University of Kentucky, Lexington, KY

N. M. Shah, University of Kentucky, Lexington, KY

D. A. Puleo, University of Kentucky, Lexington, KY

T. D. Dziubla, University of Kentucky, Lexington, KY

257

PEI-Silica Hybrid Coating for Controlling Biodegradation Rate of Magnesium

M. Kang, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea,

T. Jang, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea,

H. Jung, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea,

S. Kim, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea,

S. Jung, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea,

H. Kim, Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea,

258

Plasma-treated substrates reduces protein adsorption as studied by electron spectroscopy for chemical analysis

B. D. Ratner, University of Washington, Seattle, WA

259

SNEP - Silver Nanoparticles Embedded in Polymers: A New Class of Implant Coatings to Prevent Biofilm Formation

L. Actis, University of Texas at San Antonio, San Antonio, TX

A. Srinivasan, University of Texas at San Antonio, San Antonio, TX

A. Ramasubramanian, University of Texas at San Antonio, San Antonio, TX

J. L. Ong, University of Texas at San Antonio, San Antonio, TX

260

Protein Adsorption and Affects on Platelet Adhesion and Bacterial Adhesion on Submicron Textured Biomaterial Surfaces

L. Xu, The Pennsylvania State University, College of Medicine, Hershey, PA

C. Siedlecki, The Pennsylvania State University, College of Medicine, Hershey, PA

261

Interactions of Lipoproteins with a Polyurethane and PEO-Modified Polyurethane

R. M. Cornelius, McMaster University,

J. Macri, McMaster University,

K. M. Cornelius, McMaster University,

J. L. Brash, McMaster University,

337

Preparation and characterization of a decellularized dermis-polymer complex for the use in percutaneous devices

K. Nam, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

T. Kimura, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

A. Kishida, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan