Con-current Oral Abstract Presentations Session 7

Advances and Challenges in Biomaterial-Associated Infection and Pathogenesis

263

Antimicrobial Performance of Surface Modifications Inspired by Plant Polyphenols

T. S. Sileika, Northwestern University, Evanston, IL

D. G. Barrett, Northwestern University, Evanston, IL

P. B. Messersmith, Northwestern University, Evanston, IL

264

Selenium Nanoparticle Coated Paper Towels Prevent Various Bacterial Growth

Q. Wang, Northeastern University, Boston, MA

T. Webster, Northeastern University, Boston, MA

265

Effect of LL-37 Peptide in Disrupting Biofilms

B. Li, West Virginia University School of Medicine, Morgantown, WV

J. Noore, West Virginia University School of Medicine, Morgantown, WV

W. Artrip, West Virginia University School of Medicine, Morgantown, WV

S. McHenry, West Virginia University, Morgantown, WV

266

Mitigation of Biofilm Formation with an Elastomeric Barrier Membrane System

A. M. Tatara, Rice University, Houston, TX

S. R. Shah, Rice University, Houston, TX

D. S. Puperi, Rice University, Houston, TX

B. M. Watson, Rice University, Houston, TX

K. J. Grande-Allen, Rice University, Houston, TX

M. E. Wong, University of Texas Health Science Center at Houston, Houston, TX

A. G. Mikos, Rice University, Houston, TX

F. K. Kasper, Rice University, Houston, TX

267

PNDJ Delivering Gentamicin Controls Orthopaedic Infection in a Rabbit Model

R. Y. McLemore, Banner Good Samaritan Medical Center, Phoenix, AZ

D. J. Overstreet, Sonoran Biosciences, Phoenix, AZ

A. C. McLaren, Banner Good Samaritan Medical Center, Phoenix, AZ

B. L. Vernon, Arizona State University, Tempe, AZ

268

In vitro and in vivo biocompatibility of D-amino acid/polyurethane polymeric biocomposites for bacterial biofilm prevention in bone defects

A. J. Harmata, Vanderbilt University, Nashville, TN

C. J. Sanchez, U.S. Institute of Surgical Research, Jbsa Fort Sam Houtson, TX

A. D. Talley, Vanderbilt University, Nashville, TN

K. J. Zienkiewicz, Vanderbilt University, Nashville, TN

J. C. Wenke, U.S. Institute of Surgical Research, Jbsa Fort Sam Houtson, TX

S. A. Guelcher, Vanderbilt University, Nashville, TN

Advances in Three Dimensional Scaffolds for Tissue Regeneration II

269

Collagen Fiber Matrix Coating on Cell Surfaces for Development of Cell-Density Controllable 3D-Thick TIssues

C. Liu, Osaka University, Osaka, Japan

M. Akashi, Osaka University, Osaka, Japan

270

Sequential Click Reactions for Polymerizing and Functionalizing Hydrogel Biomaterials

D. L. Alge, University of Colorado, Boulder, CO

K. S. Anseth, University of Colorado, Boulder, CO

271

Hyaluronic Acid – Calcium Phosphate Nano Composite via in-situ Precipitation

S. Jeong, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

T. Jang, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

H. Jeong, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

M. Kang, Department of Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

H. Kim, Demartment of Materials Science and Engineering, Seoul National University, Seoul, Korea, Republic of

272

3D Printing of Complex Scaffolds Using Freeform Reversible Embedding of Suspended Hydrogels (FRESH)

T. J. Hinton, Carnegie Mellon University, Pittsburgh, PA

A. W. Feinberg, Carnegie Mellon University, Pittsburgh, PA

273

Optimization of Injectable Anisotropic Chitosan-based Hydrogels and in vivo Evaluation

K. J. Walker, Oklahoma State University, Stillwater, OK

S. V. Madihally., Oklahoma State University, Stillwater, OK

274

Reduced Graphene Oxide Incorporated Myocardial Matrix as a Functional Scaffold for Cardiac Tissue Engineering

J. H. Tsui, University of Washington, Seattle, WA

J. Jang, POSTECH, Pohang, Korea, Republic of

N. Neal, University of Washington, Seattle, WA

D. Cho, POSTECH, Pohang, Korea, Republic of

D. Kim, University of Washington, Seattle, WA

275

Optimization of Endothelial Cell (HUVEC)-Gingival Fibroblasts Co-cultures in Perfused Degradable/Polar/Hydrophobic/Ionic Polyurethane (D-PHI) Scaffolds

J. Cheung, University of Toronto,

C. A. G. McCulloch, University of Toronto,

J. P. Santerre, University of Toronto,

276

Rapid Assembly of Perfusable and Vascularizable Modular Constructs for Hepatic Tissue Engineering

R. T. Annamalai, Wayne State University, Detroit, MI

H. W. T. Matthew, Wayne State University, Detroit, MI

Alternative Bearing Surfaces

277

Comparison Between Surface Roughness and Wettability on Retrieved Metal and Ceramic Femoral Heads

A. W. Wusylko, Clemson University, Clemson, Sc, SC

R. Freed, Clemson University, Clemson Sc, SC

J. Brandt, Concordia Joint Replacement Group,

T. Turgeon, Concordia Hip & Knee Institute,

K. Kornev, Clemson University, Clemson, SC

M. Harman, Clemson University, Clemson, SC

278

Metal-on-Metal Hip Wear Measurement of Retrievals, Methodology and Validation

J. Vincelli, Dartmouth College, North Kingstown, RI

279

Adverse Local Tissue Response in Metal-On-Metal Surface Replacement Compared to Metal-On-Polyethylene Bearings with Corroded Modular Junctions

D. J. Hall, Rush University Medical Center, Chicago, IL

R. M. Urban, Rush University Medical Center, Chicago, IL

C. J. Della Valle, Rush University Medical Center, Chicago, IL

H. J. Cooper, Rush University Medical Center, Chicago, IL

J. O. Galante, Rush University Medical Center, Chicago, IL

J. J. Jacobs, Rush University Medical Center, Chicago, IL

280

The Effect of Methane Concentration on Micro-textured Ti6Al4V-carbide Hardness and Specimen Weight Gain

S. J. L. Sullivan, University of Maryland, Baltimore County, Mount Airy, MD

L. D. T. Topoleski, University of Maryland, Baltimore County, Baltimore, MD

281

Fretting Corrosion Analysis of 316L Stainless Steel (316LSS) under 240 Grit, 320 Grit and 600 Grit Surface Roughness

A. Shenoy, Syracuse Biomaterials Institute, Syracuse, NY

J. Gilbert, Syracuse Biomaterials Institute, Syracuse, NY

282

Particles from vitamin-E-diffused highly cross-linked UHMWPE induce less osteolysis compared to highly cross-linked virgin UHMWPE in a murine calvarial bone model

D. A. Bichara, Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, MA

E. Malchau, Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, MA

N. Hylleholt, Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, MA

S. Cakmak, Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, MA

O. K. Muratoglu, Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, MA

E. Oral, Massachusetts General Hospital, Boston, MA

283

Metal-on-Metal Hip Wear Patterns of Explanted Components Do Not Match Simulator Results

J. Vincelli, Dartmouth College, North Kingstown, RI

284

Developing Loading Conditions for Experimental and Computational Knee Simulators

C. Fitzpatrick, University of Denver, Denver, CO

Biomaterials Microenvironment for Stem Cells and Tissue Regeneration III

285

Heparin Coating for Controlled Biomolecule Presentation to Mesenchymal Stem Cell Spheroids

J. Lei, Georgia Institute of Technology, Atlanta, GA

L. McLane, Georgia Institute of Technology, Atlanta, GA

J. Curtis, Georgia Institute of Technology, Atlanta, GA

J. S. Temenoff, Georgia Institute of Technology, Atlanta, GA

286

Plasma-based hydrogels for the treatment of deep-partial thickness burns

D. M. Burmeister, US Army Institute of Surgical Research, Fort Sam Houston, TX

D. C. Roy, US Army Institute of Surgical Research, Fort Sam Houston, TX

B. M. Ford, US Army Institute of Surgical Research, Fort Sam Houston, TX

R. E. Coronado, US Army Institute of Surgical Research, Fort Sam Houston, TX

S. Natesan, US Army Institute of Surgical Research, Fort Sam Houston, TX

R. J. Christy, US Army Institute of Surgical Research, Fort Sam Houston, TX

287

Enzymatically degradable poly (ethylene glycol) hydrogels for long term maintenance and differentiation of human embryonic stem cell derived pancreatic precursor cells.

L. D. Amer, University of Colorado Boulder, Boulder, CO

M. J. Mahoney, University of Colorado Boulder, Boulder, CO

S. J. Bryant, University of Colorado Boulder, Boulder, CO

288

In Vitro Tumor Invasion and Metastasis Assays Using 3D-Human Tumor Models with Blood- and Lymph-Capillary Networks

A. Nishiguchi, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan

M. Matsusaki, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan

M. Akashi, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan

289

Infected Apical Papillae of Immature Permanent Teeth Retain the Regenerative Capacity

J. Oh, Seoul National University, Seoul, Korea, Republic of

Y. Yoo, Seoul National University, Seoul, Korea, Republic of

W. Lee, Seoul Nationa University, Seoul, Korea, Republic of

K. Woo, Seoul National University, Seoul, Korea, Republic of

290

Integrin-Specific Hydrogels for the Delivery of Human Mesenchymal Stem Cells in Bone Repair

A. Y. Clark, Georgia Institute of Technology, Atlanta, GA

A. J. Garcia, Georgia Institute of Technology, Atlanta, GA

291

Engineered Hyaluronic acid based Hydrogels for Survival and Transplantation of Stem Cells

A. K. Jha, University of California, Berkeley, Berkeley, CA

K. M. Tharp, University of California, Berkeley, Berkeley, CA

J. Ye, University of California, San Francisco, Sanfrancisco, CA

J. L. Santiago-Ortiz, University of California, Berkeley, Berkeley, CA

W. M. Jackson, University of California, Berkeley, Berkeley, CA

D. V. Schaffer, University of California, Berkeley, Berkeley, CA

Y. Yeghiazarians, University of California, SanFrancisco, Sanfrancisco, CA

K. E. Healy, University of California, Berkeley, Berkeley, CA

292

Protein stabilized and sustained deliverable nanofiber ‘smart scaffold’ for multiphase tissue regeneration

J. Giri, Indian Institute of Technology, Hyderabad, Hyderabad, India

B. Chandra, American Dental Association Foundation, Gaithersburg, MD

N. Kumar, American Dental Association Foundation, Gaithersburg, MD

M. T. Cicerone, National Institute of Standards and Technology, Gaithersburg, MD

Implantable Drug Delivery Systems for Medical Devices and Cancer Therapy

293

Hydrogel Dopped with Nanoparticles for Local Sustained Release of siRNA in Breast Cancer

N. Segovia, IQS, Barcelona, Spain

V. Ramos, IQS, Barcelona, Spain

S. Borros, IQS, Barcelona, Spain

N. Artzi, MIT, Cambridge, MA

294

Development of a Novel Release Phantom for Improved In Vitro-In Vivo Correlation of Drug Release From In Situ Forming Polymer Implants

C. Hernandez, Case Western Reserve University, Cleveland Heights, OH

L. Solorio, Case Western Reserve University, Cleveland, OH

H. Zhou, Case Western Reserve University, Cleveland, OH

A. A. Exner, Case Western Reserve University, Cleveland, OH

295

Functional Denture Materials for Rechargeable, Long-term Antifungal Drug Delivery

Y. Sun, UMass Lowell, Lowell, MA

296

Noninvasive Characterization of Polymer Degradation and Erosion using Ultrasound Elastography (UE)

H. Zhou, Case Western Reserve University, Cleveland, OH

M. Goss, Case Western Reserve University, Cleveland, OH

A. Gawlik, Case Western Reserve University, Cleveland, OH

C. Hernandez, Case Western Reserve University, Cleveland, OH

A. Exner, Case Western Reserve University, Cleveland, OH

297

In vivo Evaluation of Porous Dexamethasone Releasing Coatings for Glucose Biosensors in Diabetic Rat Animal Model

S. G. Vallejo-Heligon, Duke University, Durham, NC

B. Klitzman, Duke University, Durham, NC

W. M. Reichert, Duke University, Durham, NC

298

Fabrication and characterization of PLGA-loaded BCNU microcapsules produced via electrojetting for drug delivery to brain tumors

P. Fattahi, The Pennsylvania State University, State College, PA

A. Borhan, The Pennsylvania State University, University Park, PA

M. R. Abidian, The Pennsylvania State University, University Park, PA

299

Dual Antibiotic Delivery from Chitosan Sponges Prevents In Vivo Polymicrobial Biofilm Infections

J. K. Smith, University of Memphis, Memphis, TN

A. C. Parker, University of Memphis, Memphis, TN

J. A. Jennings, University of Memphis, Memphis, TN

K. E. Beenken, University of Arkansas for Medical Sciences, Little Rock, AR

M. S. Smeltzer, University of Arkansas for Medical Sciences, Little Rock, AR

W. Haggard, University of Memphis, Memphis, TN

300

Mesenchymal Stromal Cells as a Cellular Delivery Platform of Prostate Cancer Prodrugs

O. Levy, Brigham and Women's Hospital/Harvard Medical School, Cambridge, MA

N. Brennen, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD

E. Han, BWH/HMS, Cambridge, MA

S. Ranganath, BWH/HMS, Cambridge, MA

J. Ngai, BWH/HMS, Cambridge, MA

D. Rosen, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD

S. Billet, Cedars Sinai, Los Angeles, CA

N. Bhowmick, Cedars Sinai, Los Angeles, CA

S. Denmeade, Johns Hopkins, Baltimore, MD

J. Isaacs, Johns Hopkins, Baltimore, MD

J. Karp, BWH/HMS, Cambridge, MA

Microenvironments for Osteogenesis and Vasculogenesis - Physical, Chemical, and Biological Perspectives

301

Tuning Poly(Ethylene Glycol) Hydrogel Mechanics Independent of Density via Peptide Sequence

R. M. Schweller, Duke University, Durham, NC

J. L. West, Duke University, Durham, NC

302

Osteoblast Response and Osseointegration of Direct Metal Laser Sintered Titanium Implants

S. L. Hyzy, Virginia Commonwealth University, Richmond, VA

D. J. Cohen, Virginia Commonwealth University, Richmond, VA

A. Cheng, Georgia Institute of Technology, Emory University, Peking University, Richmond, VA

B. D. Boyan, Virginia Commonwealth University, Georgia Institute of Technology, Richmond, VA

Z. Schwartz, Virginia Commonwealth University, University of Texas Health Science Center, Richmond, VA

303

PEG Hydrogels Functionalized with a Collagen-mimetic Peptide and Vascular Endothelial Growth Factor Promote Enhanced Network Formation of HUVECs and Therapeutic Value in Bone Defects

J. Garcia, Georgia Institute of Technology, Atlanta, GA

A. J. Garcia, Georgia Institute of Technology, Atlanta, GA

304

Roles of Nanofiber Structure and Chemistry in Directing Stem Cell Morphology, Osteogenic Differentiation and Gene Expression

S. Sarkar, National Institute of Standards and Technology, Gaithersburg, MD

B. A. Baker, National Institute of Standards and Technology, Gaithersburg, MD

D. Chen, University of Maryland, College Park, MD

P. Pine, National Institute of Standards and Technology, Gaithersburg, MD

J. H. McDaniel, National Institute of Standards and Technology, Gaithersburg, MD

W. Losert, University of Maryland, College Park, MD

M. Salit, National Institute of Standards and Technology, Gaithersburg, MD

C. G. Simon, Jr., National Institute of Standards and Technlogy, Gaithersburg, MD

J. Dunkers, National Institute of Standards and Technology, Gaithersburg, MD

305

Combinatorial Cassette for Screening of Osteogenesis by Transplanted Human Bone Marrow Stromal Cells

S. Bodhak, National Institute of Standards & Technology (NIST) / National Institutes of Health (NIH), Gaithersburg, MD

L. Fernandez de Castro Diaz, National Institutes of Health/NIDCR, Bethesda, MD

S. A. Kuznetsov, National Institutes of Health/NIDCR, Bethesda, MD

T. Kilts, National Institutes of Health/NIDCR, Bethesda, MD

M. F. Young, National Institutes of Health/NIDCR, Bethesda, MD

S. Lin-Gibson, National Institute of Standards and Technology, Gaithersburg, MD

P. G. Robey, National Institutes of Health/NIDCR, Bethesda, MD

C. G. Simon, Jr., National Institute of Standards and Technology, Gaithersburg, MD

306

Osteogenesis in Encapsulated Cultures of Mesenchymal Stem Cells: A Modular Platform for Improved Bone Regeneration

K. B. Miles, Wayne State University, Detroit, MI

H. W. T. Matthew, Wayne State University, Detroit, MI

308

Regulation of HIF1 pathway enhanced osteogenic differentiation of mMSCs in MCNP scaffold

D. S. Oh, Columbia University, New York, NY

J. Back, Columbia University, New York, NY

M. Hong, Columbia University, New York, NY

D. Shim, Duke University, New York, NY

J. Ko, Vassar College, New York, NY

F. Lee, Columbia University, New York, NY

H. Tawfeek, Columbia University, New York, NY