Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Sensory Biomaterials and Tissues
Room: Chelan 4
About
Bioelectronics, electronics designed to interface with biology in vitro and in vivo, are an important class of biomaterials that are gaining significant interest. Bioelectronic devices include: (i) wearable sensors for health monitoring, (ii) in vitro diagnostics and biosensors that provide an electrical signal output proportional to an analyte, (iii) implantable devices (e.g. pacemakers, blood glucose monitoring, drug delivery, optoelectronics), (iv) electrophysiology (ECG, EMG, EEG) and (v) electrical stimulation of cells or tissues for tissue engineering, enhanced regeneration and therapeutic intervention. This symposium will highlight recent efforts in bioelectronics, including fabrication advances for improved properties such as size, softness, flexibility, degradability and biocompatibility as well as investigating their use in new applications.
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Invited Speaker(s)
Biomaterial Technologies for Hemostasis and Wound Care
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Cardiovascular Biomaterials
Room: Yakima 1
About
Stopping bleeding (hemostasis) and providing short and long-term wound care via passive and/or bioactive mechanisms is an important area of biomaterials-based technologies and includes external, intracavitary and intravascular hemostats, dressings, powders, foams, fibers and gels. The goal of this session is to highlight recent advances in hemostatic biomaterials and to facilitate discussion of best practices for moving hemostatic technologies from the benchtop to the clinic. The proposed session will invite presentations from researchers in this field that discuss biomaterials design, structure-property-function relationships, and achieved/ongoing/future visions of technology translation pathways. An emphasis will be placed on translational aspects of hemostatic technologies.
Abstracts
Biomaterials for Regenerative Engineering 1
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Tissue Engineering and Regenerative Medicine
Room: Chelan 2
About
Due to disease, degeneration, or trauma, there is a tremendous need to repair damaged tissues and organs. Although surgical replacement can be performed to address this issue, the insufficient number of donors greatly limits the applicability of this approach. Therefore, it is essential to develop engineered multifunctional biomaterials to promote tissue regeneration. Regenerative engineering combines biomaterial-based approaches with stem cell therapies and developmental biology to regenerate or repair tissues and organs. This session will cover tunable biocompatible materials such as hydrogels, fibers, proteins, carbohydrates, nano/micro-porous scaffolds, and metals, to modulate cellular microenvironments. The biomaterials that can direct cell fate and promote differentiation will also be highlighted by this session. Moreover, the biomaterials that can facilitate drug delivery and immunomodulation will be covered through oral and poster presentations. Furthermore, we will include discussions for the development and commercialization of various medical devices such as blood contacting implants, prostheses, and pacemakers in the session. In addition to engineering approaches, we will also provide discussions on clinical translation of biomaterial-based strategies. We expect that our interdisciplinary session including material science, chemistry, biology, engineering, and medicine will be of great significance to the clinicians, industry members and professors in academia.
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Invited Speaker(s)
Non-Viral Delivery for Gene Therapy and Editing
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Therapeutic Delivery
Room: Skagit 2
About
Targeted genome editing using programmable nucleases has recently rapidly transformed from a technique on the bench to a potential avenue for the treatment of genetic disorders and diseases. Three main types of nucleases, including zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered, regularly interspaced, short palindromic repeat (CRISPR)-associated endonuclease Cas9 have been harnessed to introduce precise and specific genome sequence change at virtually any genome locus of interest. The therapeutic relevance of genome editing, however, is challenged by the safe and efficient delivery of nuclease into targeted cells ex vivo and in vivo. This symposium will cover the fundamentals, perspective and challenge of genome editing, and highlight the recent advances that have been made on non-viral delivery of genome-editing nucleases for therapy.
Abstracts
Panel Discussion: Establishing Industry Experiences During Graduate School
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Career Catalysis
Room: Yakima 2
About
Graduate programs offer students rigorous scientific training in an academic setting, but rarely provide the opportunity to explore career paths in industry. In our proposed session, we seek to disseminate best practices for establishing a training program at a university where graduate students are able to gain industry experience during their academic training. We will host professors that have successfully established training programs at their universities, as well as PhD trainees that have completed such programs, to discuss the benefits and potential drawbacks of incorporating industry experience during PhD training. This session is being proposed by the Young Scientist Group and would be included in the Career Catalysis Track
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Invited Speaker(s)
Recent Advances in Antimicrobial and Antibiofilm Materials 2
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Musculoskeletal and Craniofacial Biomaterials
Room: Skagit 3
About
Microbial infections are among the leading causes of death worldwide. Drug resistance and lack of new antimicrobial therapeutics increase the difficulty of treating these infections. Microbial biofilms can also severely complicate treatment and lead to chronic infections. These three-dimensional, surface attached microbial structures can form on a range of medical devices and biological surfaces and exhibit sophisticated defense mechanisms, evading traditional antimicrobial therapies. This session will focus on recent advances spanning industry and academia in developing materials for the treatment of bacterial, fungal, viral, biofilm and polymicrobial infections. Strategies discussed may range from synthesis of new antimicrobial molecules and macromolecules to fabrication of antimicrobial surfaces, device coatings, nano- and micro-particle drug carriers, hydrogels, etc.
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Invited Speaker(s)
Surface Characterization and Modification SIG
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Functional Biomaterials and Surfaces
Room: Chelan 5
Abstracts
Thought Leader: ICF Fellows Session: Debate: In-situ Approaches for Tissue Creation are Better than ex-vivo Approaches
Timeslot: Friday, April 5, 2019 - 10:30am to 12:30pm
Track: Thought Leader
Room: Skagit 4/5
About
This is a special session, organized by the International College of Fellows of Biomaterials Science and Engineering. Following the model of a traditional British debate, a team of Fellows will argue that the creation of tissues in-situ is a better approach than the pre-assembly of tissues ex-vivo. Another team will argue for the opposite. In the course of the debate, this fundamental choice in tissue engineering will be thoroughly illuminated from multiple angles and the audience will vote on which team provided the most convincing arguments.