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3-Minute Thesis Competition

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Essex A-C, 4th Floor

About

In a 3-Minute Thesis (“3MT”) Competition, students present a single static slide as a compelling summary of their dissertation research and its broader impacts. Presentations must be at most three minutes and targeted to a non-technical audience. 3MT is a great way to practice your presentation skills and think about how to convey the significance of your work.

Abstracts

Abstracts will be available for download on April 27, 2022.

Antimicrobial and Antibiofilm Biomaterials Strategies – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Harborside Ballroom A-B, 4th Floor

About

Treatment of microbial infections is complicated by rising antibiotic resistance and the inherent difficulty of treating biofilm-associated infections. In both scenarios, many current FDA approved antimicrobial drugs are ineffective, leading to a significant health and economic burden. Compounding these issues is a lack of development of new antimicrobial drug classes limiting the pipeline of available therapeutics. Advances in antimicrobial biomaterial therapies have the potential to improve outcomes for bacterial, fungal, viral, and biofilm-associated infections. Innovations in biomaterials are critically needed in the face of the COVID-19 pandemic, both for treatments of the SARS-CoV-2 virus, and also for effective treatment of the severe bacterial and fungal co-infections that have been reported. This session will cover biomaterials approaches to treat bacterial, fungal, and viral infections, including the prevention and eradication of biofilms. Strategies discussed may include antimicrobial surface modifications, device coatings, drug delivery, and immune engineering approaches.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 PM 47. Synthetic Mucus Hydrogels for the Delivery of Antimicrobial Peptides, Sydney Yang*, Gregg Duncan, PhD, University of Maryland, College Park, College Park, MD, USA

  • 2:50:00 PM 48. Lysostaphin-delivering hydrogels for the promotion of bone healing and infection mitigation in a murine fem- oral fracture model, Jeremy Caplin(1)*, Julie Gordon(2), Pranav Kalelkar(1), Chris Johnson(1), Rodney Donlan(3), John Peroni(2), Andrés García(1); (1)Georgia Institute of Technology, Atlanta, GA, USA, (2)University of Georgia, Athens, GA, USA, (3)Centers for Disease Control and Prevention, Atlanta, GA, USA

  • 2:55:00 PM 49. Smart bacterial hunting for wound healing, Malcolm Xing*, University of Manitoba, Winnipeg, MB, Canada

  • 3:00:00 PM 50. Effect of Commercially Available Wound Irrigation Solutions on Unin- fected Host Tissue in a Murine Model, Dexter Powell, MD(1), Brendan Comer, MD.(1), Bin Wu, MD.(1), Paula Diets, MS.(1), Therese Bou-Akl, MD., PhD.(1,2), Wei-ping Ren, MD., PhD.(1,2)*, David Markel, MD.(1,2); (1)Ascension Providence Hospital, Southfield, MI, USA, (2)Wayne State University, Detroit, MI, USA

  • 3:05:00 51. Loading a First-In-Class Antibiofilm Compound into Polyurethane Foam for Negative Pressure Wound Therapy, Tyler Smith(1)*, Kaden Rawson(1), Travis Newberger(1), Isaac Bell(1), Spencer Brown(1), Paul Sebahar, PhD(1,2), Ryan Looper, PhD(1,2), Paul Pasquina, MD(3,4), Brad Isaacson, PhD, MBA, MSF(3,5), John Shero, MHA(6), Dustin Williams, PhD(1,2); (1)University of Utah, Salt Lake City, UT, USA, (2)Curza Global, Salt Lake City, UT, USA, (3)Department of Physical Medicine and Rehabilitation, The Center for Rehabilitation Sciences Research, Uniformed Services University of the Health Sciences, Bethesda, MD, USA, (4)Department of Rehabilitation, Walter Reed National Military Medical Center, Bethesda, MD, USA, (5)The Geneva Foundation, Tacoma, UT, USA, (6)DoD-VA Extremity Trauma and Amputation Center of Excellence, Joint Base San Antonio Fort Sam Houston, TX, USA

  • 3:15:00PM 52. Modifying Ti Wires with Pep- toid-Loaded Microgels to Inhibit Intra-Operative OR Contamination, Wenhan Zhao(1)*, Matthew Libera(1), Annelise Barron(2), Haoyu Wang(1), Hongjun Wang(1), Lauren De Stefano(3), Jordan Katz(3), Jennifer Lin(2); (1)Stevens Institute of Technology, Hoboken, NJ, USA, (2)Stanford University, Stanford, CA, USA, (3)Orthobond Corporation, Monmouth Junction, NJ, USA

  • 3:20:00 PM 53. Physiochemical and bactericidal activity evaluation: Silver-augmented 3D-printed scaffolds—An in vitro study, Vasudev Nayak, MSci(1,2)*, Nick Tovar, PhD, DDS(1), Jacques Hacque- bord, MD(3), Pablo Atria, DDS, MSci(1), Simone Duarte, DDS, PhD(4), Caroline Tonone, DDS(4), Beatriz Panariello, DDS, PhD(4), Paulo Coelho, DDS, PhD, MBA(1,2), Lukasz Witek, MSci, PhD(1,2); (1)NYU College of Dentistry, New York, NY, USA, (2)New York University Tandon School of Engineering, Brooklyn, NY, USA, (3)NYU Grossman School of Medicine, New York, NY, USA, (4)Indiana University School of Dentistry, Indianapolis, IN, USA

  • 3:25:00 54. Cathodic Voltage-Controlled Electrical Stimulation of SS316L for Eradication of Methicillin-Resistant Staphylococcus aureus, Gowtham Mohanraj*, Menachem Tobias, Mark Ehrensberger, University at Buffalo, Buffalo, NY, USA

  • 3:30:00 PM 55. Characterization of silanized titanium loaded with 2-heptylcyclopro- pane-1-carboxylic acid, Zoe Harrison, Josh Bush, PhD*, Felio Perez, PhD, Joel Bumgardner, PhD, Tomoko Fujiwara, PhD, Daniel Baker, PhD, Rachel Wiley, Jessica Jennings, PhD, University of Memphis, Memphis, TN, USA

  • 3:35:00 56. Prevention of Staphylococcus aureus Biofilm Infections on Titanium Alloy Ti64 and Polyethylene Using Cathodic Voltage-Controlled Electrical Stimulation, Kevin McPhillips, M.S.*, Menachem Tobias, M.S., Mark Ehrensberger, PhD, University at Buffalo, Buffalo, NY, USA

Biomaterial Systems for Immunomodulation and Immune Cell Therapy – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Laurel A-B, 4th Floor

About

We have only recently begun to appreciate the immune system's ability to prevent and cure disease; however, unlocking its full potential to fight disease will require the implementation of biomaterial technologies. This session focuses on the use of biomaterial systems to enhance and direct the immune response for therapeutic or prophylactic gain. Example biomaterial innovations in this space include lymph node-targeting nanoparticles, intradermal microneedles, and scaffolds for engineered T cell expansion as well as drug and gene delivery vehicles that modulate the function of native immune cells.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 PM 57. Bone-targeted Nanoparticles Modulate Macrophage-mediated Fracture Healing, Baixue (Dorothy) Xiao, Yuchen Wang, Marian Ackun-Farmmer*, Danielle Benoit, University of Rochester, Rochester, NY, USA

  • 2:50:00 PM 58. Basophils drive immune responses elicited by self-assem- bled peptide nanofiber vaccines, Yaoying Wu, PhD*, Hanning Wen, Benjamin Cossette, Lucas Shores, Tatiana Segura, Joel Col- lier, Duke University, Durham, NC, USA

  • 2:55:00 59. Microparticle Artificial Antigen Presenting Cell Elasticity Influ- ences Activation of Antigen-Specific T cells, Savannah Est-Witte*, Sydney Shannon, Dennis Gong, Kaitlyn Calabresi, Jonathan Schneck, MD, PhD, Jordan Green, PhD, Johns Hopkins University, Baltimore, MD, USA

  • 3:00:00 PM 60. Biomaterial Scaffolds as In Vivo CAR-T Cell Factories, Pritha Agarwalla, PhD(1), Edikan Ogun- naike, PhD(2), Fraces Ligler, PhD(1), Gianpietro Dotti, MD(2), Yevgeny Brudno(1)*; (1)Joint Department of Biomedical Engineering at UNC - Chapel Hill and NC State - Raleigh, Chapel Hill, NC, USA, (2)University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

  • 3:05:00 PM 61. In Vivo Expansion of Endoge- nous Antigen-Specific CD8+ T cells using Artificial T-Cell Stimulating Microparticles, Natalie Livingston, B.S.*, John Hickey, PhD, Sebastian Salathe, B.S., Hai-Quan Mao, PhD, Jona- than Schneck, MD, PhD, Johns Hopkins University, Baltimore, MD, USA

  • 3:15:00 PM 62. Nanoparticle-Mediated Chemoimmunotherapy Delivery to Lymph Nodes Unlocks Drug Synergies in TNBC, Margaret Manspeaker(1)*, Meghan O’Melia, PhD(1), Susan Thomas, PhD(1,2); (1)Georgia Institute of Technology, Atlanta, GA, USA, (2)Emory University School of Medicine, Atlanta, GA, USA

  • 3:20:00 PM 63. Hydrogel Platforms to Support Tolerogenic Trophoblasts for Cell Therapy, Emily Slaby*, Jessica Weaver, PhD, Arizona State University, Tempe, AZ, USA

  • 3:25:00 PM 64. Hydrolytically Degradable Microgels for Immune Cell Encapsulation, Ana Mora-Boza, PhD*, Valeria Juárez, Grad Stu- dent, Maria Coronel, PhD, Ankur Singh, Professor, Andrés García, Georgia Institute of Technology, Atlanta, GA, USA

  • 3:30:00 PM 65. High Throughput Characteriza- tion of Lysosomotropic Polymer Adjuvants, Adam Weiss(1)*, Marcos Lopez, II(1), Saikat Manna(1), Sampa Maiti(2), Wenjun Du(2), Stuart Rowan(1), Aaron Esser-Kahn(1); (1)University of Chicago, Chicago, IL, USA, (2)Central Michigan University, Mount Pleasant, MI, USA

  • 3:35:00 PM 66. Bifunctional biomaterial design to promote vessel formation and reduce macrophage activation, Aakanksha Jha*, Erika Moore, PhD, University of Florida, Gainesville, FL, USA

Biomaterial-Based In Vitro Cancer/Tumor Models for Drug Screening and Diagnostics – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Dover A-C, 3rd Floor

About

Biomaterial-based in vitro cancer/tumor models offer a close mimic of the complex tumor microenvironment, providing versatile platforms for drug and toxicology screening as well as diagnostics. The implementation of these preclinical tools can afford low-cost, easy-to-use systems to evaluate cancer treatments, enhancing the efficacy and toxicological assessment for specific patients, mitigating the limitations of current technologies, and expanding the treatment options and patient’s quality of life.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 67. HA Concentration-De- pendent Invasiveness of Patient-Derived Gliomaspheres Cultured in 3D Hydrogels, Gevick Safarians*, Itay Solomon, Alireza Sohrabi, Stephanie Seidlits, University of California, Los Angeles, Los Angeles, CA, USA

  • 2:50:00 PM 68. PEG-Based Adaptable Hydrogels Elucidate the Role of Viscoelasticity in Modulating Glioblastoma Fates in 3D, Sauradeep Sinha(1)*, Manish Ayush- man(1), Xinming Tong(2), Sarah Jones(3), Gerald Grant, MD(4), Fan Yang, PhD(1,2); (1)Bioengineering, Stanford, CA, USA, (2)Orthopaedic Surgery, Palo Alto, CA, USA, (3)Chemistry, Stanford, CA, USA, (4)Neurosurgery, Palo Alto, CA, USA

  • 2:55:00 PM 69. Breast Cancer Hydrogel Microspheres for High-Throughput Drug Screening, Yuan Tian, PhD(1), Shantanu Pradhan, PhD(1,2), Wen Seeto, PhD(1), Dmitriy Minond, PhD(3), Elizabeth Lipke, PhD(1)*; (1)Auburn University, Auburn, AL, USA, (2)Indian Institute of Tech- nology Madras, Chennai, India, (3)Nova Southeastern University, Fort Lauderdale, FL, USA

  • 3:00:00 PM 70. Decellularized Intestine Extracellular Matrix-Em- bedded Within Colorectal Tumor Spheroids to Recapitulate the Tumor Microenvironment, Michael Buckenmeyer, PhD*, Elizabeth Brooks, PhD, Madison Taylor, BS, Matthew Wolf, PhD, National Cancer Institute (NIH), Frederick, MD, USA

  • 3:05:00 PM 71. A 3D Viscoelastic Glioblastoma Model to Assess the Effects of Matrix Stiffness on Tumor Invasion and Drug Response, Sauradeep Sinha(1)*, Manish Ayushman(1), Xinming Tong(2), Sarah Jones(3), Gerald Grant, MD(4), Fan Yang, PhD(1,2); (1)Bioengineering, Stanford, CA, USA, (2)Orthopaedic Surgery, Palo Alto, CA, USA, (3)Chemistry, Stanford, CA, USA, (4)Neurosurgery, Palo Alto, CA, USA

  • 3:15:00 PM 72. Hydrogel Arrays Enable Increased Throughput for Screening Therapeutic Re- sponses in 3D Tumor Models, Stephanie Seidlits, PhD*, Alireza Sohrabi, PhD, Mary Epperson, Laila Rad, BS, Mayilone Sathialingam, Jeremy Huang, Ze Zhong Wang, PhD, Jesse Liang, University of California Los Angeles, Los Angeles, CA, USA

  • 3:20:00 PM 73. Enhanced Combinatorial Analysis of Tumor Cell- ECM Interactions Using Design-of-Experiment Optimized Microarrays, Hannah Kimmel*, Gregory Underhill, PhD, University of Illinois at Urbana-Cham- paign, Champaign, IL, USA

  • 3:25:00 PM 74. Three-Dimensional Cancer-Immune Co-culture Model Using Lyophilized Silk Fibroin Scaffolds, Katelyn Mistretta, BS*, Jeannine Coburn, PhD, Worcester Polytechnic Institute, Worcester, MA, USA

  • 3:30:00 PM 75. Fluorescence-dim- ming platforms for real-time monitoring of protease levels in tumor tissues, Miso Lee*, Oanh-Vu Pham-Nguyen, Wei Mao, Jaekeun Park, Wanho Cho, Hoai-Thuong Bui, Hyuksang Yoo, Kangwon National University, Chuncheon-si, Republic of Korea

  • 3:35:00 PM 76. Colorectal Tumor Decellularization: Comparison of Three Detergent Based Methods, Madison Taylor*, Michael Buckenmeyer, PhD, Matthew Wolf, PhD, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA

Biomaterials for Regenerative Engineering – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Waterview Ballroom, Ground Level

About

Regenerative engineering aims to develop functional, bioactive, and instructive biomaterials and approaches for the regeneration of tissues through a convergence of engineering, medicine, developmental biology, and stem cell science. This symposium will highlight recent trends in developing functional biomaterials that play an active role in controlling cellular behaviors and tissue regeneration. We will include different classes of biomaterials such as proteins, polysaccharides, synthetic polymers, fibers, metals, ceramics, and hydrogels for applications in regenerative engineering. This session will also highlight the biomaterials that can direct cell fate and promote differentiation. Moreover, the biomaterials that can facilitate drug delivery and immunomodulation will be covered through oral and poster presentations. During the symposium, translational strategies for handling these biomaterials from ‘Bench to Bedside’ will also be addressed. We expect that our interdisciplinary session, including material science, chemistry, biology, engineering, and medicine, will be of great significance to clinicians, industry members, and academia.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 PM 77. Bone regeneration capacity of intrinsically disordered peptides, Maryam Rahmati, PhD(1)*, Sabine Stoetzel, PhD(2), Thaqif El Khassawna, Professor(2,3), Chenyi Mao, PhD(4), Joshua Vaughan, PhD(4), Kamila Iskhahova, PhD(5), D.C. Florian Wieland, PhD(5), Eoghan P. Dillon, Professor(6), Ståle Petter Lyngstadaas, Professor(1), Håvard Jostein Haugen, Pro- fessor(1); (1)University of Oslo, Oslo, Norway, (2)Justus-Liebig University Giessen, Giessen, Germany, (3)University of Applied Sciences, Giessen, Germany, (4)University of Washington, Seattle, WA, USA, (5)Helmholtz Zentrum Hereon, Geesthacht, Germany, (6)Photothermal Spectroscopy Corp, Santa Barbara, CA, USA

  • 2:50:00 PM 78. Biostimulatory Stem Cell-Laden Nanofiber-Hy- drogel Composite Microgel Enhances Soft Tissue Remodeling, Zhicheng Yao*, Yueh-Hsun Yang, Jiayuan Kong, Yining Zhu, Calvin Chang, Jason Yin, Jeffrey Chao, Sashank Reddy, Hai- Quan Mao, Johns Hopkins University, Baltimore, MD, USA

  • 2:55:00 PM 79. Is a Tissue-Specific Source of Decellularized Extracellular Matrix Necessary for Vocal Fold Regeneration?, Mika Brown, MSc*, Shirley Zhu, Maryam Tabrizian, PhD, Nicole Li-Jessen, PhD, McGill University, Montreal, QC, Canada

  • 3:00:00 PM 80. Developing 3D-Printed Scaf- folds with Tunable Growth Factor-Mimetic Peptide Presentation, Kelly Seims, Fenet Demissie, Paula Cama- cho, Lesley Chow*, Lehigh University, Bethlehem, PA, USA

  • 3:05:00 PM 81. Manipulation of Non-Ionic Surfactant Chemistry to Control Emulsion Electrospun Fiber Properties and Wettability, Katherine Meinhold*, Pamela Johnson, PhD, Nathan Ohl, Justin Lehtinen, Jennifer Robinson, PhD, University of Kansas, Lawrence, KS, USA

  • 3:15:00 PM 82. Development of Modular, Cell-laden PEG Microbeads for Vascularization, Nicole Friend, MSE*, Jan Stege- mann, PhD, Andrew Putnam, PhD, University of Michigan, Ann Arbor, MI, USA

  • 3:20:00 PM 83. Particle freeze-drying allows for controlled MAP packing fraction, cell spreading, and diffusion efficiency, Alexa Anderson(1)*, Ethan Nicklow(1), Katrina Wilson(1), Sasha Cai Lesher-Perez, PhD(2), Tatiana Segura, PhD(1); (1)Duke University, Durham, NC, USA, (2)University of California, Los Angeles, Los Angeles, CA, USA

  • 3:25:00 PM 84. Hybrid 3D Printing of Synthetic and Natural Hydro- gels for Producing Hybrid Structures with Spatially Controlled Mechanical Prop- erties, Jiahui Lai*, Man Hang Mathew Wong, Min Wang, The University of Hong Kong, Hong Kong, Hong Kong

  • 3:30:00 PM 85. The Mechanical Character- ization of a Novel Cartilage Repair Scaffold, Vishal Thomas, MS(1)*, Nathan Buchweitz, BS(2), Yongren Wu, PhD(2), Jeremy Mercuri, PhD(1); (1)Clemson University, Clemson, SC, USA, (2)Clemson University - Medical University of South Carolina, Charleston, SC, USA

  • 3:35:00 PM 86. Synthetic Hydrogels Support Robust and Reproducible Cardiomyocyte Differentiation, Margot Amitrano*, Aaron Simmons, Sean Palecek, William Murphy, University of Wisconsin-Madison, Madison, WI, USA

Drug Delivery (SIG) – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Harborside Ballroom D-E, 4th Floor

About

The Drug Delivery SIG session will consider abstracts that fall with the broad areas of therapeutic development, formulation, and application testing. Drug delivery from medical devices, tissue engineering scaffolds/hydrogels, films, microparticles, nanoparticles, environmentally responsive materials, and other types of biomaterial assemblies are all invited. Studies testing drug targeting, drug combinations, and drug/cell combinations are all also welcomed to submit. Drug delivery application areas of interest include but are not limited to regenerative medicine/tissue engineering, cell and tissue transplant, cardiovascular stents and other devices, cancer, microbial infection, and autoimmune diseases.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 PM 87. Poly(lactic-co-glycolic acid) Polymers Can Refill In Situ with Drug, Kathleen Young*, Ningjing Zhang, Emma Henderson, Audrey Lord, Joel Linebach, Ananya Sahu, Horst von Recum, PhD, Case Western Reserve University, Cleveland, OH, USA

  • 2:50:00 PM 88. Lipid Nanoparticle Formu- lations Enabling Oral Gene Delivery, Samuel LoPresti, PhD*, Daria Strelkova, MS, Sai- gopalakrishna Yerneni, PhD, Rose Doerfler, James Kirkby, BS, Kathryn Whitehead, PhD, Carnegie Mellon University, Pittsburgh, PA, USA

  • 2:55:00 PM 89. Novel Type of Microneedles for Transdermal Delivery of Amphotericin B, Sina Azizi, Grad Student*, Roger Narayan, Professor, North Carolina State University and University of North Carolina, Raleigh, NC, USA

  • 3:00:00 PM 90. Smart Nanoworms for Cancer Drug delivery, Le Yu, PhD*, Mei Wei, PhD, Ohio University, Athens, OH, USA

  • 3:05:00 PM 91. Facile Fabrication of Biode- gradable Microparticles Exhib- iting Delayed Pulsatile Drug Release, Tyler Graf, Sherry Yue Qiu, Dhruv Varshney, Mei-Li Laracuente, Pujita Munnangi, Brett Pogostin, Arnav Garyali, Kevin McHugh, PhD*, Rice University, Houston, TX, USA

  • 3:15:00 PM 92. Upconversion nanoparticles coated organic photovoltaics for near infrared light con- trolled drug delivery systems, Tae Yeon Kim*, Sei Kwang Hahn, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea

  • 3:20:00 PM 93. Analysis of Mechanical Inter- locking between Elastomeric Microposts and Villi for Intesti- nal Retentive Platforms, Durva Naik*, Xiaozili Huang, Nihar Trivedi, Gaurav Balakrishnan, Christopher Bettinger, PhD, Carnegie Mellon University, Pittsburgh, PA, USA

  • 3:25:00 PM 94. Co-assembled Peptide-Protein Granules for in Vitro Cell Engineering, Renjie Liu, PhD*, Gregory Hudalla, PhD, University of Florida J. Crayton Pruitt Family, Gainesville, FL, USA

  • 3:30:00 PM 95. Crystallization of the Multi-Receptor Tyrosine Kinase Inhibitor Sorafenib for Controlled Long-Term Drug Delivery Following a Single Injection, Amanda Rakoski*, Victoria Lai, MS, Sarah Neshat, James Pitingolo, Johndavid Sabedra, Stephen Li, Aryaman Shodhan, Joshua Doloff, PhD, Johns Hopkins University, Baltimore, MD, USA

  • 3:35:00 PM 96. Scalable Fabrication of Solid Drug Nanoparticles for Efficient Glaucoma Therapy, Da Huang, PhD(1)*, Pedro Magno(2), Lin Qi(1), Xiaorong Liu, PhD(2), Hu Yang, PhD(1); (1)Missouri University of Science and Technology, Rolla, MO, USA, (2)University of Virginia, Charlottesville, VA, USA

Nanomaterials (SIG) – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Kent A-C, 4th Floor

About

The nanoscience and nanotechnology of biomaterials involves the unique science and technology present in biomaterials at the nanoscale and their related biological effects. Such nanobiomaterials present the creation of new and better biomaterials and devices, diagnostics and therapeutics for biomedical applications.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 PM 97. Structural Assessment of Polymer-En- zyme Complex Nanoparticle Stability, Sanjeeva Murthy, PhD*, Rahul Upadhya, Shashank Kosuri, Matthew Tamasi, Adam Gormley, Rutgers University, Piscatawy, NJ, USA

  • 2:50:00 PM 98. Sequestering Inflammatory Signals with Scavenger Nanoparticles, Giancarlo Tejeda*, Grad Student, Courtney Dumont, Professor, University of Miami, MIami, FL, USA

  • 2:55:00 PM 99. Biological Hydroxy- apatite Structure Determination by Electron Crystallog- raphy Techniques, Abdulelah Alrebaish(1,2)*, Otto Wilson Jr, PhD(1); (1)Catholic University, Washington, DC, USA, (2)King Saud University, Riyadh, Saudi Arabia

  • 3:00:00 PM 100. Thermo-responsive polymer micelles for high concentration volume-restricted tis- sue administration, Kyle Fergie, BS(1)*, David Wilson, PhD(1), Lucie Kracíková, BS(2), Ladislav Androvič, BS(2), Ellen Wang, BS(1), Richard Laga, PhD(2), Geoffrey Lynn, PhD(1); (1)Avidea Technolo- gies Inc., Baltimore, MD, USA, (2)Institute of Macromolecular Chemistry, Czech Academy of Scienc- es, Prague, Czech Republic

  • 3:05:00 PM 101. Temperature-de- pendent changes to fibrillization of co-assembling synthetic peptides, Ryan Clark*, Renjie Liu, Benjamin Keselowsky, PhD, Gregory Hudalla, PhD, University of Florida, Gainesville, FL, USA

  • 3:15:00 PM 102. A Novel Nanoparticle Delivery Vehicle for Transfection of microRNA-122 in Rat Articular Chondrocytes, Anne Skelton(1)*, David Cohen, MD(1), Christian DeMoya(2), Mark Grinstaff, PhD(2), Zvi Schwartz, DMD, PhD(1,3), Barbara Boyan, PhD(1,4); (1)Virginia Commonwealth University, Richmond, VA, USA, (2)Boston University, Boston, MA, USA, (3)University of Texas Health Science Center at San Antonio, San Antonio, TX, USA, (4)Georgia Institute of Technology, Atlanta, GA, USA

  • 3:20:00 PM 103. Scalable Fabrication of Dendrimer/ Plasmid DNA Nanocomplexes, Joseph Johnston*, Da Huang, Jawahar Khetan, Hu Yang, Missouri University of Science and Technology, Rolla, MO, USA

  • 3:25:00 PM 104. Synthesis and Characterization of Polymeric Nanoparticles for the Delivery of Proteins for Vascular Applications, Jordyn Wyse(1)*, Marisa Esparza(1), Aiyanna Doss(1), Dimitrios Miserlis(2), Panagiotis Koutakis(3), Marissa Wechsler(1); (1)University of Texas at San Antonio, San Antonio, TX, USA, (2)The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA, (3)Baylor University, Waco, TX, USA

  • 3:30:00 PM 105. High-Throughput Screening of Polymer Libraries for Cryoprotection of LDH, Travis Meyer, Ph.D.*, Matthew Tamasi, Adam Gormley, Ph.D., Rutgers, State University of New Jersey, Piscataway, NJ, USA

  • 3:35:00 PM 106. Star-like nanoparticles as a magneto-me- chanical actuator for cancer therapy, John Cooper, III*, Robby Moller, Juan Beltran-Huarac, PhD, East Carolina Univer- sity, Greenville, NC, USA

Tissue Engineering (SIG) – RAPID FIRE

Timeslot: Wednesday, April 27, 2022 - 2:45pm to 3:45pm
Room: Laurel C-D, 4th Floor

About

The field of tissue engineering has made significant progress in the last two decades through the development of novel biomaterials and three-dimensional scaffold fabrication methods. Efforts to engineer cell niches to control cell behavior over multiple length scales and precisely guide tissue regeneration have advanced the field. To achieve this, a diverse range of novel technologies have been leveraged, including 3D bioprinting, electrospinning, microfluidics, light-based patterning, and directed assembly, to enable notable progress in controlled release and spatial presentation of biomolecules, organ integration, production of tissue models, single cell-level presentation of microenvironmental cues, and molecular-level control of biomaterial composition. This session will highlight recent trends in novel biomaterials and scaffold development and advanced biofabrication techniques towards the development of sophisticated tool kits for tissue engineers.

Abstracts

Abstracts will be available for download on April 27, 2022.

  • 2:45:00 PM WITHDRAWN

  • 2:50:00 PM 108. Injectable Spheroid and Microgel Granular Composites for Cartilage Repair, Nikolas Di Caprio*, B.S. Bioengineering, Jason Burdick, PhD, Matthew Davidson, PhD., University of Pennsylvania, Philadelphia, PA, USA

  • 2:55:00 PM 109. Delivery and In Situ Assembly of Clickable Microparticle Hydrogel Scaffolds in Spinal Cord Injuries, Thomas Tigner, III*, Ashley Tucker, Kyra Shine, Jennifer Dulin, PhD, Daniel Alge, PhD, Texas A&M Univer- sity, College Station, TX, USA

  • 3:00:00 PM 110. WITHDRAWN (poster still available)

  • 3:05:00 PM 111. Characterization of Hydrogel/3D Printed Scaffold Composites for Osteochondral Tissue Engineering, Nettie Brown*, Scott Hollister, PhD, Johnna Temenoff, PhD, Geor- gia Institute of Technology and Emory University, Atlanta, GA, USA

  • 3:15:00 PM 112. Comparison of Compressive Properties and Cell Viability of Species-Specific Methacrylat- ed Collagen Hydrogels, Sarah Ali, Nilabh Kajave, Vipuil Kishore*, Florida Institute of Technology, Melbourne, FL, USA

  • 3:20:00 PM 113. Antimicrobial PVA Hydrogels for Crohn’s Fistula Treatment, Caitlyn Greene*, Henry Beaman, Darnelle Stinfort, Mary Beth Monroe, Syracuse University, Syracuse, NY, USA

  • 3:25:00 PM 114. In Vitro Tissue Model with Collagen and Aldehyde/Hy- drazide-Modified Hyaluronic Acid Hydrogels, Jessica Torres*, Fanfei Meng, Sathvik Madduri, Kevin Buno, Luis Solorio, Yoon Yeo, Julie Liu, Purdue University, West Lafayette, IN, USA

  • 3:30:00 PM 115. Characterizing Physical Prop- erties of Constructs 3D-Printed with Peptide-Polymer Conju- gates, Diana Hammerstone(1)*, Andrew Kitson(1), Tyler French(1), Tomas Babuska(2), Brandon Krick, PhD(2), Lesley Chow, PhD(1); (1)Lehigh University, Bethlehem, PA, USA, (2)Florida State University, Tallahassee, FL, USA

  • 3:35:00 PM 116. Electrospun, Carbon Nano- tube-Based Electroconductive Scaffolds for Cardiac Tissue Engineering Applications, Taylor Suh*, Nasif Mahmood, Mostakima Lubna, Philip Bradford, Jessica Gluck, PhD, North Carolina State University, Raleigh, NC, USA