3A: Panel Discussion: Scientific Writing: Crafting Your Story

3B: Granular Hydrogel Scaffolds

Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Silver Pearl 2


Granular hydrogel materials emerged as a class of biomaterial that provide for well-defined in vitro and in vivo systems with plug-and-play components and tissue-mimicking 3D environments. Granular hydrogels are composed of a slurry of microgel particles that are assembled to form a larger porous structure. Microporous annealed particle scaffolds (MAPS) are a subclass of granular hydrogel material with a void space network stabilized by inter-particle chemical bonds. The modular nature of granular hydrogels offers enormous tunability in not only the individual microgel design but also the homogenous or heterogenous microgel assembly into the bulk scaffold. This session will explore current advances in granular hydrogel technology, including MAPS, for both immune modulation, tissue repair, organ-on-a-chip, and 3D-printing applications.

  • 10:30 AM. 98. Conjugation of IL-33 to Microporous Annealed Particle Scaffolds Initiates Type 2 Immune Response in Vitro and in Vivo. Colleen Roosa, Samantha Lempke, Riley Hannan, PhD, Jeffrey Sturek, PhD, MD, Sarah Ewald, PhD, Donald Griffin, PhD, University of Virginia.

  • 10:45 AM. 99. Injectable Cellular Spheroid and Microgel Granular Composites for Cartilage Repair. Nikolas Di Caprio, Matthew D. Davidson, PhD, Jason A. Burdick, PhD, University of Pennsylvania, Biofrontiers Institute.

  • 11:00 AM. 100. Biomaterial Microstructure and Spatial Bioactivity in Microporous Annealed Particle (MAP) Scaffolds Guides Endothelial Cell Patterning and Lumen Formation. Alexa Anderson, Dimitris Ntekoumes, Sharon Gerecht, PhD, Tatiana Segura, PhD, Duke University, Johns Hopkins University.

  • 11:15 AM 101. Impact of Thiol-Ene and Tetrazine Click Annealing Chemistry on Osteogenic Outcomes in a Calvarial Defect Model. Sarea Recalde Phillips, Elizabeth Ruben, Talia Baig, Carl Gregory, PhD, Daniel L. Alge, PhD, Texas A&M University.

  • 11:30 AM 102. Influence of Microgel and Interstitial Matrix Compositions on Granular Hydrogel Composite Properties. Dr. Victoria Muir, Jason A. Burdick, University of Pennsylvania, University of Colorado.

  • 11:45 AM 103. Single Microgel Species for Forming Guest-Host Microporous Annealed Particle PEG-MAL Hydrogels. Adrienne Widener, Abilene Roberts, Jorge Santini-Gonzalez, Edward A. Phelps, PhD, University of Florida.

3C: Fibrous Biomaterials for Tissue Engineering

Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Silver Pearl 3


As tissue engineering and regenerative medicine aims to recapitulate native microenvironments, fibrous biomaterials are being developed with great success. The fibrous nature of the biomaterials mimics the fibrous extracellular matrix. This session will highlight the design, fabrication, characterization and use of fibrous biomaterials for use in those applications. We will include both natural and synthetic polymer approaches, as well as functional characterization and analysis of the fibrous biomaterials. Additionally, we are soliciting abstracts that detail the design and fabrication of fibrous biomaterials for any tissue engineering application.

  • 10:30 AM 104. Electrospinning of Decellularized Tissue to Harness its Angiogenic and Immunoregulatory Bioactivity. Sarah Jones, Del Donehoo, Shreya Raghavan, PhD, Elizabeth Cosgriff-Hernandez, PhD, University of Texas at Austin, Texas A&M University.

  • 10:45 AM 105. Directed Wet Spinning of Reactive Macromers to Fabricate Multi-Fiber Hydrogel Scaffolds. Mattheew Davidson, PhD, Jason Burdisk, PhD, University of Colorado Boulder.

  • 11:00 AM 106. Discrete Electrospun Microfibers Influence Granular Hydrogel Properties. Gregory Grewal, Georgia T. Helein, Jenna L. Sumey, Steven R. Caliari, PhD, Christopher B. Highley, PhD, University of Virginia.

  • 11:15 AM 107. Magnetic Alignment of Electrospun Fiber Segments Within a 3D Hydrogel Composite Guides Tendon Fibroblast Spreading and Multicellular Epithelial Migration Phenotype Switching. Harrison L. Hiraki, Daniel L. Matera, PhD, Robert N. Kent III, Samuel J. DePalma, Brendon M. Baker, PhD, University of Michigan.

  • 11:30 AM 108. Anisotropic Guides for Neuronal Regeneration Generated by Microfluidic-Assisted Interfacial Polyelectrolyte Complexation of Extracellular Matrix Biomolecules. Rui R. Costa, PhD, Dr. David Caballero, Dr. Diana Soares da Costa, Romen Rodriguez-Trujillo, Subhas Kundu, PhD, rui L. Reis, Iva Pashkuleva, PhD, University of Minho, ICVS/3B’s, Barcelona Institute of Science and Technology (BIST), University of Barcelona.

  • 11:45 AM. 109. Fibrosis Development in Engineered Adipose Tissue Models of Obesity. Evangelia Bellas, PhD, Golnaz Anvari, Anthony Berger, PhD, Nikolas Di Caprio, BS, Temple University.

3D: Biomaterials for Organoids

Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Coral 1-2


An organoid is a self-organized three-dimensional tissue that is typically derived from stem cells (pluripotent, fetal or adult) and which mimics the critical functional, structural, and biological complexity of an organ, such as the gut, brain, eye, pancreas, liver, kidney, and lung. Organoids bridge a gap in existing model systems by providing a more stable system amenable to extended cultivation and manipulation while more representative of in vivo physiology. This session will cover the most recent advancements of biomaterials-mediated organoid and organ chip technologies in regenerative medicine, cancer therapy, drug testing, environmental control, monitoring, adaptive sensing, and translational applications. This topic was well-received in the previous SFB meetings and is an exciting emerging research area. In 2023, we will continue this session and promote the translational impacts of biomaterials-mediated organoid projects.

  • 10:30 AM. 110. Induced Epithelial Curvature in Photopatterned Intestinal Organoids Regulates Symmetry Breaking via Pre-Transcriptional Changes in Membrane Tension and Resting Potential. Bruce Kirkpatrick, Francis Yavitt, Radu Moldovan, PhD; Peter Dempsey, PhD; Kristi Anseth, PhD. University of Colorado Medical Scientist Training Program, University of Colorado Boulder Department of Chemical and Biological Engineering, BioFrontiers Institute, University of Colorado Anschutz Advanced Light Microscopy Core, University of Colorado Anschutz Department of Pediatrics.

  • 10:45 AM. 111. Study Transportation of Drugs within Newly Established Colon Organoid Systems. Qun Wang, Dr. Zahra Davoudi. Iowa State University.

  • 11:00 AM. 112. Pancreatic Differentiation of iPSC in Thiol-Norbornene Photo-Click Hydrogels. Chien-Chi Lin, PhD; Matthew Arkenberg. Purdue University.

  • 11:15 AM. 113. Spatially Controlled Fabrication of Assembloids with 3D Bioprinting. Michelle Huang, Julien Roth, Lucia Brunel, Yueming Liu, Betty Cai, Sauradeep Sinha, Fan Yang, PhD, Sergiu Pasca, MD, Sungchul Shin, PhD, Sarah Heilshorn, PhD. Stanford University.

  • 11:30 AM. 114. Rapid and Facile Light-Based Approach to Generate Gut-On-A-Chip Systems Asing Synthetic Hydrogels. Ana Mora-Boza, PhD, Adriana Mulero-Russe, Ankur Singh, Andrés J. García. Georgia Institute of Technology.

  • 11:45 AM. 115. Engineering Human Induced Pluripotent Stem Cell Derived Neural Tissue Constructs for Modeling Neuroinflammation and Neurotoxicity. Joydeb Majumder, PhD, Elizabeth Torr, William L. Murphy, PhD. University of Wisconsin-Madison.

3E: Biomaterials for the Lungs

Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Coral 3-4


The COVID-19 pandemic and its long-term consequences has put lung health in the spotlight. Advances in biomaterial design, drug delivery systems and microfabrication techniques offer new opportunities for probing disease mechanisms and novel therapies for lung diseases. These approaches can be used to develop treatments for acute conditions such as virus infections, to investigate mechanisms of chronic disease progression, for toxicology testing, and may even eliminate the need for animal experimentation in the future. This symposium will focus on the opportunities associated with using biomaterials to engineer the lung microenvironment, therapeutic delivery and potential impacts on clinical translation in pulmonary medicine.

  • 10:30 AM 116. INVITED SPEAKER.

  • 11:00 AM. 117. Local Matrix Stiffening as an Ex-Vivo Model of Early Pulmonary Fibrotic Remodeling. Donia Ahmed, Jingyi Xia, Rachel L. Zemans, M.D., Brendon M Baker, Ph.D., Claudia Loebel, M.D., Ph.D. University of Michigan.

  • 11:15 AM. 118. Engineering a 3D Distal Lung Co-Culture Model of Human Pulmonary Fibrosis. Alicia E. Tanneberger, BS, MS, Chelsea M. Magin, PhD. University of Colorado Denver Anschutz.

  • 11:30 AM. 119. Engineered Lung Microtissue to Model Macrophage-Regulated Pulmonary Fibrosis and Anti-Fibrosis Treatment. Ruogang Zhao, Ying Xu. State University of New York at Buffalo.

  • 11:45 AM. 120. Lung-Mimetic Sealant: Lab-to-Market Translation via Biomedical Technology Accelerator. Meghan R. Pinezich, PhD, Mohammad Mir, Pamela L. Graney, PhD, Daniel Naveed Tavakol, Sarah R. Kaslow, MD, Panpan Chen, MD, Jiawen Chen, Maria R. Hudock, Olimpia Gavaudan, Brandon A.Guenthart, MD, Matthew Bacchetta, MD, John D. O'Neill, PhD, Jinho Kim, PhD, Gordana Vunjak-Novakovic, PhD. Columbia University, Stevens Institute of Technology, Stanford University, Vanderbilt University.

3F: Smart Biomaterials

Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Coral 5


Smart biomaterials (i.e., targeted, stimuli-, bio-responsive, autonomous) are those that change one or more of their properties in response to a stimulus. These biomaterial systems have great potential for the efficient delivery of therapeutics, increasing therapeutic activity, while decreasing toxicity and other adverse effects like drug resistance. This session will describe the state-of-the-art on the design, development, and application of smart biomaterials in different areas of medicine including tissue engineering, drug delivery, medical devices, tissue regeneration, antimicrobial, remineralization, self-healing, and immune engineering.

  • 10:30 AM. 121. Enzyme-Responsive “Smart” Hydrogels for Triggered Delivery of Antibiotics to Infected Wounds. Akram Abbasi, Zhaowei Jiang, Alec Mccall, Brian LeBlanc, Anita Shukla, Brown University, Rhode Island Hospital.

  • 10:45 AM 122. Enzymatically-Responsive Shape Memory Polymers for Infection Surveillance and Biofilm Removal in Chronic Wounds. Maryam Ramezani, Mary Beth Monroe, PhD, Syracuse University.

  • 11:00 AM 123. Biodegradable Piezoelectric Nanofibers for Biomedical Applications. Thinh Le, Thanh Nguyen, PhD, The University of Connecticut.

  • 11:15 AM 124. An Injectable Smart Piezoelectric Hydrogel for Periodontal Disease Treatment. Santiago Orrego, PhD, Lina Roldan, DDF, Carolina Montoya, PhD, Varun Solanki, DDS, Temple University.

  • 11:30 AM 125. Photo-Carbon Monoxide Releasing Molecules for Dual Antibacterial and Vascular Cell Impacts. Cjris Bashur, PhD, Merfat Hammad, Nicholas Huynh, Dr. Adnan Elgattar, Yi Liao, PhD, Florida.

  • 11:45 AM 126. Precisely Controlled Antimicrobial Peptide Delivery Hydrogels for Diabetic Wound Healing. Sang Hoon Jeong, Sei Kwang Hahn, Pohang University of Science and Technology.

3G: Emerging Innovations and Translation in Orthopedic Biomaterials Science and Engineering

3H: Industry Rising Star Competition

Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Shorebreak


This session will be an industry research-focused competition for all young scientists currently employed at a non-academic, non-government position in industry. Each participant must specifically emphasize how their research advances the state of the field/industry that they work in and supports the translation of biomaterials to the clinic/market.

  • 10:45 AM 132. Modeling Cell-Material Interactions in Wounds with A Novel Human Keratin Matrix In Vitro. Allison N. Ramey-Ward, ProgenaCare Global LLC.

  • 10:55 AM 133. 3D In Vitro Model of Oral Mucosa for in-Lab Assessment of Dental Materials and Oral Wound Care Products. Fahimeh Tabatabaei, iFyber, LLC.

  • 11:05 AM 134. Gonzalo Muñoz Taboada, BioDevek Information to Come. Gonzalo Muñoz Taboada, BioDevek .

  • 11:15 AM 135. HABP Functionalized Electrospun PCL Fibers as a Candidate for Building an Artificial Synovial Membrane. Hosein Mirazi, South Dakota School of Mines and Technology.

  • 11:25 AM 136. Enzymatically-Responsive Shape Memory Polymers for Chronic Wound Infection Surveillance and Biofilm Removal. Maryam Ramezani, BioInspired Syracuse.

  • 11:35 AM 137. Tuning Thermo-Mechanical Properties of Shape Memory Polymer Foams for Biomedical Applications. Marziya Hasan, Shape Memory Medical Inc.