6A: Panel Discussion: Emerging Scholars in Biomaterials

6B: Biomaterials for Regenerative Engineering RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Silver Pearl 2

About

Regenerative engineering aims to develop functional, bioactive, and instructive biomaterials and approaches for the regeneration of tissues through the convergence of engineering, medicine, developmental biology, and stem cell science. This symposium will highlight recent trends in developing functional biomaterials that play an active role in controlling cellular behaviors and tissue regeneration. We will include different classes of biomaterials such as proteins, polysaccharides, synthetic polymers, fibers, metals, ceramics, and hydrogels for applications in regenerative engineering. This session will also highlight the biomaterials that can direct cell fate and promote differentiation. Moreover, oral and poster presentations will cover the biomaterials that can facilitate drug delivery and immunomodulation. Translational strategies for taking these biomaterials from ‘Bench to Bedside’ will also be discussed during the symposium. We expect our interdisciplinary session, including material science, chemistry, biology, engineering, and medicine, will be of great significance to clinicians, industry members and academia.

  • 11:30 AM. 271. Functionalization of 3D-Printed Scaffolds with 2D Heterostructures and Immuno-regulative Cytokines for Osteo-Immunomodulated Bone Repair. Xifeng Liu, PhD, Lichun Lu, PhD, Mayo Clinic, Rochester, MN, USA.

  • 11:35 AM 272. In Vitro Screening of Engineered Extracellular Matrices as Tissue Engineered Periosteum to Promote Allograft Healing. Alyson March, Yiming Li, PhD, YoungJoo Lee, Regine Choe, PhD, Danielle Benoit, PhD, University of Rochester, Rochester, NY, USA, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea, University of Oregon, Eugene, OR, USA.

  • 11:40 AM 273. Anisotropy and Stiffness of Tunable Collagen Scaffolds Drive Endothelial Inflammatory Phenotype, Myogenesis and Osteogenesis. Yong How Tan, Krista Habing, Karina Nakayama, PhD, Oregon Health & Science University, Portland, OR, USA.

  • 11:45 AM 274. Elucidating Mechanism of Action of Injectable Extracellular Matrix Hydrogel in a Model of Tongue Fibrosis. Emma Zelus, BS, Marianna Alperin, MD, MS, Andrew Vahabzadeh-Hagh, MD, Karen Christman, PhD, UC San Diego, La Jolla, CA, USA.

  • 11:50 AM 275. Licensed hMSCs Exhibit Enhanced Immunomodulatory Capacity in a Biomaterial Mediated Manner. Vasiliki Kolliopoulos, BS, Brendan Harley, PhD, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

  • 12:00 PM 276. Gaussian Curvature-Driven Direction of Cell Fate Towards Osteogenesis with Triply Periodic Minimal Surface Scaffolds. Xin Zhao, PhD, The Hong Kong Polytechnic University, ,Hong Kong, China.

  • 12:05 PM 277. 3D Printing with Photopolymerizable Polyester Resins for Resorbable Tissue Scaffold Applications. Mathew Stanford, M.S., Melinda Harman, Ph.D., Michael Vaughn, Ph.D, Poly-Med, Inc., Anderson, SC, USA, Clemson University, Clemson, SC, USA.

  • 12:10 PM 278. Semi-Synthetic Hyaluronic Acid Hydrogels Promote Muscle Regeneration by Inducing BAT Differentiation of FAPs. Morgan Pfaff, Anouk Killaars, PhD, Derek Ning, Michael Davies, MD, Anthony Nguyen, Prashant Nuthalapati, Mengyao Liu, Xuhui Liu, PhD, Brian Feeley, MD, Kevin Healy, PhD, University of California, Berkeley, Berkeley, CA, USA, University of California, San Francisco, San Francisco, CA, USA.

  • 12:15 PM 279. Combinatorial Effects of Surface Modification of Poly (glycerol-dodecanedioate) on Chondrocyte Behavior. Yue Qin, PhD, Rhima Coleman, PhD, University of Michigan,, Ann Arbor, MI, USA.

  • 12:20 PM 280. Investigating The Combinatory Effect of Raspberry Ketone and Simvastatin on In Vitro Osteodifferentiation for Application in Guided Bone Regeneration. Matthew Atwill, Joel Bumgardner, PhD, The University of Memphis, Memphis, TN, USA, The University of Tennessee Health Science Center, Memphis, TN, USA.

6C: Drug Delivery (SIG) RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Silver Pearl 3

About

The Drug Delivery Special Interest Group will deal with the science and technology of controlled release of active agents from delivery systems. Controlled drug release is achieved by the use of diffusion, chemical reactions, dissolutions or osmosis, used either singly or in combination. While the vast majority of such delivery devices are based on polymers, controlled release can also be achieved by the use of mechanical pumps. In a broader sense, controlled release also involves control over the site of action of the active agent, using the active agent using pro-drugs, targetable water soluble polymers or various microparticulate systems. Relevant aspects of toxicology, bioavailability, pharmacokinetics, and biocompatibility are also included.

  • 11:30 AM. 281. Host-Modified Hydrogels Enable Sustained Release Through Engineered Biomolecule Avidity. Arielle D'Elia, M.S., Christopher Rodell, PhD, Drexel University, Philadelphia, PA, USA.

  • 11:35 AM 282. Engineering Siloxane-Derived Lipid Nanoparticles for Tissue-Specific mRNA Therapeutics Delivery. Lulu Xue, PhD, Gan Zhao, PhD, Ningqiang Gong, PhD, Xuexiang Han, Sarah Shepherd, Claude Clarence Warzecha, Rakan El-Mayta, Mohamad-Gabriel Alameh, Lili Wang, Drew Weissman, Andrew Vaughan, James Wilson, Michael Mitchell, Department of Bioengineering, Philadelphia, PA, USA, School of Veterinary Medicine, Philaldelphia, PA, USA, Perelman School of Medicine, Philadelphia, PA, USA, Department of Medicine, Phialdelphia, PA, USA.

  • 11:40 AM 283. Tissue-reactive Drugs Enable Materials-free Local Depots. Rukesh Chinthapatla, Sharda Pandit, Belen Neumann-Rivera, Sandeep Palvai, Nicholas Massaro, Joshua Pierce, Yevgeny Brudno, North Carolina State University, Raleigh, NC, USA.

  • 11:45 AM 284. Targeting the Protease-Activated Receptor-2 (PAR2) with Nanotherapeutics to Reduce Oral Cancer Pain. Divya Bhansali, MS, Tu Nguyen, PhD, Tianyu Li, PhD, Kenji Inoue, PhD, Chloe Peach, PhD, Raquel Tonello, PhD, Dane Jensen, PhD, Nigel Bunnett, PhD, Brian Schmidt, MD, DDS, PhD, Kam Leong, PhD, Columbia University, New York, NY, USA, New York University, New York, NY, USA.

  • 11:50 AM 285. Engineering Ligand-Tethered Lipidoids for Targeted RNA Delivery to Treat Liver Fibrosis. Xuexiang Han, Ningqiang Gong, Lulu Xue, Margaret Billingsley, Sarah Shepherd, Michael Mitchell, University of Pennsylvania, Philadelphia, PA, USA.

  • 12:00 PM 286. Zwitterionic Peptide Sequence Determines Anti-Fouling Behavior and Protein Adsorption Profile on Nanoparticle Surfaces. Clyde Overby, III, M.S., Danielle Benoit, Ph.D,University of Rochester, Rochester, NY, USA, University of Rochester Medical Center, Rochester, NY, USA, University of Oregon, Eugene, OR, USA.

  • 12:05 PM 287. Uricase Functionalized Hydrogel for the Localized Treatment of Gout. Madeline Fuchs, Gregory Hudalla, PhD, Benjamin Keselowsky, University of Florida, Gainesville, FL, USA.

  • 12:10 PM. 288. A Local Release, Reloadable Antibiotic Delivery Device Manages Biofilm Hardware-Related Infection Better than Clinical Standards. Robert Falconer, Walker Kay, Connor Hunt, Jacob Adams, Alice Miller, Korinna Hylen, Tyler Smith, Lisa Nehring, Brooke Kawaguchi, Richard Epperson, Brian Barnum, Nicholas Ashton, PhD, Dustin Williams, PhD, University of Utah, Salt Lake City, UT, USA, Purgo Scientific, Draper, UT, USA.

  • 12:15 PM 289. Dual Responsive Nanoparticles for Precision Therapy of Rheumatoid Arthritis. Gizem Erensoy, PhD, Luca Menges, Tilia Selldén, Alexandra Stubelius, PhD, PharmD, Chalmers University of Technology, Gothenburg, Sweden.

  • 12:20 PM 290. Self-Assembled Oligo-Urethane Nanoparticles for Intracellular Delivery of mRNA. Suja Shrestha, Ryan Marks, Sina Fatehi, Allen Teng, Meghan McFadden, PhD, Ronald Cohn, Evgueni Ivakine, Anthony Gramolini, Paul Santerre, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada, Translational Biology and Engineering Program (TBEP) and Ted Rogers Centre for Heart Research, Toronto, ON, Canada, Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada, Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada, Department of Physiology, University of Toronto, Toronto, ON, Canada, Institute of Biomedical Engineering, Toronto, ON, Canada.

6D: Immune Engineering (SIG) RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Coral 1-2

About

Over the past decade the focus of many bioengineers and clinicians has been shifting towards "immune engineering" approaches that include but are not limited to engineered biomaterials for vaccines, immunotherapy (immune-modulation), cell and gene therapy, immune microenvironment engineering, and systems immunology. These research areas embrace a comprehensive list of translational immunology-associated problems including chronic infections, autoimmune diseases, aggressive cancers, allergies, etc. The purpose of the Immune Engineering SIG is to bring together emerging ideas and provide a venue for professional interaction to a large number of academic and industrial research groups and scientists working in these areas.

  • 11:30 AM 291. Monitoring Melanoma Responses to STING Agonism and Focused Ultrasound Thermal Ablation Using Microneedles and Ultra-Sensitive Single Molecule Arrays. Daniel Dahis, PhD Student, Michele Dion, PhD Student, Alexander Cryer, PhD, Tal Gilboa, PhD, Mariana Alonso, Michael Lewandosky, PhD, Nuria Puigmal, Haim Azhari, PhD, Rushdy Ahmed, PhD, David Walt, PhD, Natalie Artzi, PhD, Technion Institute of Technology, Haifa, Israel, Brigham and Women's Hospital, Boston, MA, USA, Wyss Institute, Boston, MA, USA, MIT, Cambridge, MA, USA.

  • 11:35 AM 292. Cytokine-Loaded Nano-in-Cryogel Biomaterials for Repolarization of Tumor Associated Macrophages. Sydney Henriques, Ori Chalom, Evan Glass, PhD, Sohini Roy, PhD, Abigail Manning, Benjamin Hacker, Marjan Rafat, PhD, Laura Kennedy, MD, Fiona Yull, PhD, Young Kim, MD, PhD, Todd Giorgio, PhD, Vanderbilt University, Nashville, TN, USA, Vanderbilt University Medical Center, Nashville, TN, USA.

  • 11:40 AM 293. Augmented Anticancer Efficacy of Natural Killer Cells via Surface Functionalized Quantum Dots Using PD-1 Binding Peptides. Sehwan Jeong, Kyobum Kim, Min-Jae Choi, Woo-jin Jeong, Dongguk University, Seoul, Republic of Korea, Inha University, Incheon, Republic of Korea.

  • 11:45 AM 294. Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering. Alex Hamilton, Michael Mitchell,University of Pennsylvania, Philadelphia, PA, USA.

  • 11:50 AM 295. Antigen-Decorated Liposomal Hydrogels for Robust and Durable Protection against SARS-CoV-2 Infections. Julie Baillet, John Klich, Ben Ou, Sebastien Lecommandoux, Eric Appel, Stanford University, Stanford, CA, USA, University of Bordeaux, Talence, France.

  • 12:00 PM 296. Cationic Exosomes Anchored with Receptor Antagonist of IL-1 for Cartilage Targeting and Repair. Tanvi Vinod Pathrikar, Chenzhen Zhang, Helna Baby, Ambika Bajpayee, Northeastern University, Boston, MA, USA.

  • 12:05 PM 297. In Situ Engineering of an Immunologically Active Tumor Microenvironment with Cold-Responsive Nanoparticles for Cryoimmunotherapy of Breast Cancer. Wenquan Ou, PhD, Samantha Stewart, BS, Alisa White, MS, James Shamul, MS, Xiaoming He, PhD, University of Maryland, College Park, MD, USA.

  • 12:10 PM 298. mRNA Lipid Nanoparticles for ex vivo Engineering of Primary Human T Cells for Autoimmunity Therapies. Ajay Thatte, Alex Hamilton, Margaret Billingsley, Alvin Mukalel, Michael Mitchell, PhD, University of Pennsylvania, Philadelphia, PA, USA.

  • 12:15 PM 299. Development of Intranasal Vaccine System Using Hyaluronic Acid-Coated Polymeric Micelles. Yuichi Ohya, PhD, Kengo Suzuki, Yuta Yoshizaki, PhD, Nobuo Murase, PhD, Kenta Horii, Takuma Kato, Akinori Kuzuya, PhD, Kansai University, Suita, Japan, Tohoku University, Sendai, Japan.

  • 12:20 PM 300. IL-12-Based Cytokine Factories Modulate Tumor Microenvironment to Eradicate Pancreatic Tumors in Mice and are Well Tolerated in Non-human Primates. Samira Aghlara-Fotovat, Bertha Castillo, Peter Rios, Sofia Ghani, Ira Joshi, Douglas Isa, Jose Oberholzer, Omid Veiseh, Amanda Nash, Rice University, Houston, TX, USA, CellTrans Inc, Chicago, IL, USA.

6E: 3D and Nano Biomaterials RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Coral 3-4

About

This session covers the development of three-dimensional (3D) biomaterial platforms, such as hydrogels, bioprinted materials, electrospun scaffolds as well as nanomaterials for tissue engineering and drug delivery applications. It focuses on in vitro models for the study of tissue physiology and disease pathology for a variety of diseases such as glaucoma, cancer, and lupus. On the drug delivery side, it explores the development of new nanodevices, such as bone-targeted nanoparticles, vaccine gene delivery platforms, or cancer therapies.

  • 11:30 AM 301. Modeling Age in Macrophage-Endothelial Interactions and Therapeutic Interventions in a 3D PEG Hydrogel. Justin Silberman, Erika Moore, PhD, University of Florida, Gainesville, FL, USA.

  • 11:35 AM 302. A 3D Platform to Study Monocyte Activation in Systemic Lupus Erythematosus. Holly Ryan, Mark Segal, MD, PhD, Erika Moore, University of Florida, Gainesville, FL, USA.

  • 11:40 AM 303. A 3D Bioprinted Hydrogel-Based Microfluidic Device for Anti-Cancer Drug Screening. Amir K. Miri, Anant Bhusal, New Jersey Institute of Technology, Newark, NJ, USA, Rowan University, Glassboro, NJ, USA.

  • 11:45 AM 304. 3D Printed Gelatin Methacrylate Models for Normal and Glaucomatous Trabecular Meshwork Studies. Bikram Adhikari, Mina Pantcheva, MD, Melissa Krebs, PhD, Colorado School of Mines, Golden, CO, USA, University of Colorado School of Medicine, Aurora, CO, USA.

  • 11:50 AM 305. Desmoplastic Pancreatic Adenocarcinoma Mimicking Hydrogels for Modelling 3D Cancer Spheroids. Menekse Ermis, MD, PhD, Natashya Falcone, PhD, Natan Barros, PhD, Marvin Mecwan, PhD, Reihaneh Haghniaz, PhD, Auveen Choroomi, Mahsa Monirizad, Yangzhi Zhu, PhD, Ali Khademhosseini, PhD, Junmin Lee, PhD, Han-Jun Kim, Terasaki Institute for Biomedical Innovation, Los Angeles, CA, USA, 2Pohang University of Science and Technology (POSTECH), Pohang, Kyungbuk, Republic of Korea.

  • 12:00 PM 306. Development of an Injectable Upconversion Nanoparticle conjugated Doxorubicin Theranostics Electrospun Nanostructure for Breast Cancer. Amreen Khan, Mayuri Gandhi, Jayesh Bellare, Professor, Rohit Srivastava, Indian Institute of Technology Bombay India, Mumbai, India.

  • 12:05 PM 307. Bone-Targeted Nanoparticles Modulate Macrophage-Mediated Fracture Healing. Baixue (Dorothy) Xiao, Danielle Benoit, Marian Ackun-Farmmer, Yuchen Wang, University of Rochester, Rochester, NY, USA, University of Oregon, Eugene, OR, USA.

  • 12:10 PM 308. Effect of Lipid Saturation and Cholesterol Concentration on Liposome Interaction with Fungal and Mammalian Cells. Veronica LaMastro, Kayla Campbell, PhD, Peter Gonzalez, Tobias Meng-Saccoccio, Anita Shukla, PhD, Brown University, Providence, RI, USA.

  • 12:15 PM 309. Lipid-Polymer Hybrid “Particle-in-Particle” Nanostructure Gene Delivery Platform Explored for Lyophilizable DNA and mRNA COVID-19 Vaccines. Zhongyu Li, Xiaoyang Xu, New Jersery Institute of Technology, Newark, NJ, USA.

  • 12:20 PM 310. Investigation of the Protein Corona’s Impact on Nanoliposome Drug Delivery Systems in Cancer Cells Using QCM-D. Nicholas Van Der Sanden, Maryam Tabrizian, PhD, McGill University, Montreal, QC, Canada.

6F: Engineering Cells and Their Microenvironments (SIG) RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Coral 5

About

The Engineering Cells & Their Microenvironments Special Interest Group concentrates on technologies and approaches focused at the single cell level and encompassing engineering cell microenvironments, biomaterial-induced cell signaling, stem cell manufacturing and differentiation, immunoengineering, and biomaterials for cell-based detection and diagnosis.

  • 11:30 AM 311. Spatial Confinement Modulates Macrophage Response in Microporous Scaffolds. Alejandra Suarez-Arnedo, Yining Liu, Lindsay Riley, Eleanor Caston, Tasman Miley, Michelle Schneider, Tatiana Segura,Duke University, Durham, NC, USA.

  • 11:35 AM 312. Optogenetically-Controlled Bacterial Persistence. Yousr Dhaouadi, BS Chemical Engineering, Dacheng Ren, Syracuse University, Syracuse, NY, USA.

  • 11:40 AM 313. Compressive Mechanical Load Modulates the Secretome and Cytoskeleton of MSC Spheroids. Sabrina Mierswa, Victoria Thai, J. Kent Leach, PhD, University of California Davis, Davis, CA, USA.

  • 11:50 AM 315. Nanoparticle Interaction with Extracellular Matrix Stabilizes Cartilage Tissue Integrity. Ula von Mentzer, Gizem Erensoy, PhD, Stefanny de Fatima Guedes Cunha, Sara Yousefialdashi, Alexandra Stubelius, PhD, PharmD, Chalmers University of Technology, Gothenburg, Sweden.

  • 12:00 PM 316. Tunable Gelatin Methacrylate Polyethylene Glycol Hydrogels for Cell Mechanosensing Applications. Eya Ferchichi, Silviya Petrova Zustiak, PhD, Saint Louis University, Saint Louis, MO, USA.

  • 12:05 PM 317. Fibronectin’s EDA Region Mechanoregulates Matrix Microarchitecture During Wound Healing. Jennifer Patten, Michael Kegel, Fatima Ahmed, Patrick Halligan, Karin Wang, Temple University, Philadelphia, PA, USA.

  • 12:10 PM 318. The Influence of Hyaluronic Acid Properties on Natural Killer Cell Function in an Engineered Hydrogel System. Suzanne Lightsey, Madison Temples, Benjamin Kaufman, Tiffany Conklin, Blanka Sharma, University of Florida, Gaineville, FL, USA.

  • 12:15 PM 319. Atomic Vacancy Rich 2D Nanoparticles Drive Mitochondrial Biogenesis and Bioenergetics. Kanwar Abhay Singh, John Soukar, Mohammad Zulkifli, Irtisha Singh, Vishal Gohil, Akhilesh Gaharwar, Texas A&M University, College Station, TX, USA, Texas A&M Health Science Center, Bryan, TX, USA.

  • 12:20 PM 320. Co-assembled Peptide-Protein Granules for Cytosolic Protein Delivery. Stephanie Herrera, Renjie Liu, PhD, Jennifer Simonovich, Gregory Hudalla, PhD, Benjamin Keselowsky, PhD, University of Florida, Gainesville, FL, USA.

6G: Cardiovascular Biomaterials (SIG) RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Seaglass

About

The Cardiovascular Biomaterials Special Interest Group has the mission to foster the professional interaction and address the common concerns of academic and industrial scientists and engineers, clinicians, and regulatory professionals concerned with the discovery, research, development, and use of biomaterials for cardiovascular devices and implants.

  • 11:30 AM 321. Implantable Vascular Platform with Multi-Material Stent and Printed, Soft Sensors for Wireless Monitoring of Restenosis. Robert Herbert, Woon-Hong Yeo, Georgia Institute of Technology, Atlanta, GA, USA.

  • 11:35 AM 322. 3D-Printed Low-Profile and Mechanically Competent Bioresorbable Vascular Scaffolds. Yonghui Ding, PhD, Cheng Sun, PhD, Guillermo Ameer, ScD, Northwestern University, Evanston, IL, USA.

  • 11:40 AM. 323. Substrate Stiffness Modulates Endothelial Phenotypic Transition. Maedeh Zamani, PhD, Yu-Hao Cheng, MD, Patrick Cahan, PhD, Ngan Huang, PhD, Stanford University, Stanford, CA, USA, Johns Hopkins University, Baltimore, MD, USA.

  • 11:45 AM 324 Development and Testing of Combinatorial Biomaterials for Increased Biocompatibility. Christopher Siedlecki, PhD, Yi Wu, Keren Beita, Chad Schmeidt, DVM, Hitesh Handa, PhD, Li-Chong Xu, PhD, Penn State College of Medicine, Hershey, PA, USA, University of Georgia, Athens, GA, USA.

  • 11:50 AM 325. Cell-Laden Bead Bath to Support Extrusion Bioprinting of Vascularized Constructs. Irene Zhang, Nicole Friend, Emily Margolis, Andrew Putnam, PhD, University of Michigan, Ann Arbor, MI, USA.

  • 12:00 PM 326. Pro-healing Nanomatrix Coated Stent Analysis in an In Vitro Vascular Double-Layer System and in a Rabbit Model. Ho-Wook Jun, Xixi Zhang, Jun Chen, Brigitta Brott, Peter Anderson, Patrick Hwang, Jennifer Sherwood, Gillian Huskin, Young-sup Yoon, Renu Virmani. University of Alabama at Birmingham, Birmingham, AL, USA, Endomimetics, LLC, Birmingham, AL, USA, CVPath Institute, Inc., Gaithersburg, MD, USA.

  • 12:05 PM 327. Decoy Exosomes Offer Protection Against Chemotherapy-Induced Cardiotoxicity. Maio Fan, Ke Cheng, Southern Medical University, NC State University.

  • 12:15 PM 329. Targeting Tissue-resident Macrophage Secreted MCP-1 for Attenuating Inflammation After Myocardial Infarction. Jiaxing Wen, Ya Guan, PhD, Hong Niu, PhD, Yu Dang, PhD, Jianjun Guan, PhD, Washington University in St. Louis, Saint Louis, MO, USA.

  • 12:20 PM 330. Metallic Bioresorbable Flow Diverters for the Treatment of Intracranial Aneurysms. Alexander Oliver, BS, Cem Bilgin, MD, Andrew Vercnocke, BS, Kent Carlson, PhD, Ramanathan Kadirvel, PhD, Roger Guillory, II, PhD, Adam Griebel, MS, Jeremy Schaffer, PhD, Dan Dragomir-Daescu, PhD, David Kallmes, MD, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA, Mayo Clinic, Rochester, MN, USA, Michigan Technological University, Houghton, MI, USA, Fort Wayne Metals, Fort Wayne, IN, USA.

6H: Tissue Engineering (SIG) RAPID FIRE

Timeslot: Friday, April 21, 2023 - 11:30am to 12:30pm
Room: Shorebreak

About

Tissue Engineering SIG is a forum to exchange information, further knowledge, and promote greater awareness regarding all aspects of the use of biomaterials to engineering tissue substitutes or to promote tissue regeneration. Of primary interest and relevance to TE SIG is the use of appropriate materials (synthetic and natural) with cells (either native or from a donor source) and/or biological response modifiers (e.g., growth factors, cytokines and other recombinant products) to replace tissue and organ functions. Particular emphasis is placed on the development of materials to better incorporate, protect, and deliver both the cells and biological response modifiers to help promote the healing and regenerative processes. The group is committed to forging interactions among basic scientists, applied scientists, engineers, clinicians, industrial members, professional societies in related fields, and regulatory groups in its efforts to expand and effectively utilize the shared knowledge base in this multidisciplinary field.

  • 11:30 AM 331. Fibrous Topographical Cues Govern Tenogenic vs. Chondrogenic Fate Switch. Robert Kent, III, MS, Maggie Jewett, BS, Daniel Matera, PhD, Ariella Shikanov, PhD, Brendon Baker, PhD, University of Michigan, Ann Arbor, MI, USA.

  • 11:35 AM 332. Engineering Adipose Tissue Using Edible Scaffolds with Tunable Stiffness for Cultured Meat. Kathleen Chen, Sam Norris, Amy Rowat, Associate Professor, Nora Kawecki, University of California, Los Angeles, Los Angeles, CA, USA.

  • 11:40 AM 333. Preliminary Analysis of the Effect of Dissolution Products of SCPC Resorbable Bioactive Ceramic on Nerve Cells. Arjun Tiwari, PhD, In Hong Yang, University of North Carolina at Charlotte.

  • 11:45 AM 334. A Nanofiber-Hydrogel Scaffold Embedded with Adipose-Derived Stem Cells for Treatment of Crohn’s Perianal Fistulas. Zhicheng Yao, Ling Li, Susan Gearhart, Florin Selaru, Hai-Quan Mao, Alyssa Parian, Johns Hopkins University, Baltimore, MD, USA, The Johns Hopkins University School of Medicine, Translational Tissue Engineering Center, Baltimore, MD, USA, The Johns Hopkins University, Institute for NanoBioTechnology, Baltimore, MD, USA, The Johns Hopkins University, Whiting School of Engineering, Department of Materials Science and Engineering, Baltimore, MD, USA, The Johns Hopkins University School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, MD, USA, The Johns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD, USA, The Johns Hopkins University, Whiting School of Engineering, Department of Biomedical Engineering, Baltimore, MD, USA.

  • 11:50 AM 335. Vascularizing 3D Printed GelMA Hydrogel for Pancreatic Islet Transplantation. Martha Fowler, M.S., Boram Kim, Cody Fell, Michael Doerfert, M.S., Shalini Pandey, PhD, Joe Swain, Chris Wright, Jeffrey Hartgerink, PhD, Omid Veiseh, PhD, Rice University, Houston, TX, USA.

  • 12:00 PM 336. Development of Shrink Wrapped Endothelial Tubule Segments for Tissue Vascularization. Shubhangi Sathyakumar, Rachelle Palchesko, Ph.D., Jacqueline Bliley, Ph.D., Adam Feinberg, Ph.D, Carnegie Mellon University, Pittsburgh, PA, USA.

  • 12:05 PM 337. Conductive Electrospun Polymer Platforms Improve Stem Cell-Derived Cardiomyocyte Function and Maturation. Gisselle Gonzalez, Aileena Nelson, Erin LaMontagne, Alexander Whitehead, PhD, Ritwik Vatsyayan, Shadi Dayeh, PhD, Adam Engler, PhD, University of California, San Diego, La Jolla, CA, USA.

  • 12:10 PM 338. Light-Pipe FRESH 3D Bioprinting for Engineering Spatial Heterogeneity of Tissue Scaffolds. Caner Dikyol, Adam Feinberg, PhD, Carnegie Mellon University, Pittsburgh, PA, USA.

  • 12:15 PM 339. Two-dimensional Nanosilicates Stimulate Angiogenesis in Endothelial Cells. Giriraj Lokhande, Kanwar Abhay Singh, Anna Kersey, Irtisha Singh, Ph.D, Akhilesh Gaharwar, Texas A&M University, College Station, TX, USA, Texas A&M Health Science Center, Bryan, TX, USA.

  • 12:20 PM 340. Incorporating Elastomeric Particles into Bioinks to Enhance 3D-Printed Tissues Stability. Shira Landau, PhD, Jennifer Kieda, Sargol Okhovatian1, Kaitlyn Ramsay, PhD, Chuan Liu, Milica Radisic, PhD, University of Toronto, Toronto, ON, Canada.