1A: PANEL: New Investigators Anonymous: Navigating the Academic Path Together

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: Grand Ballroom
Session Type: Panel Discussion

Description

This moderated panel session will explore the highs and lows of managing a research lab, balancing teaching responsibilities, and navigating the path to tenure. It provides a unique opportunity for early-stage investigators to network and gain invaluable advice from seasoned faculty members at various career stages.

Moderators:

Mykel Green, Tulane School of Science and Engineering
Teresa Rapp, University of Oregon

Speakers

1B: Biomaterials for Functional Vasculature

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: BLVD B
Session Type: General Session

Description

This session will focus on the latest advancements in biomaterials designed to support the formation, maintenance, and repair of functional vasculature. Key areas of discussion will include the role of biomaterials in promoting angiogenesis and vasculogenesis, as well as biofabrication techniques such as 3D printing and bioprinting for creating complex vascular networks. Special emphasis will be placed on how biomaterial properties influence vascular cell behavior and vascular organization. Researchers will present cutting-edge ideas and advancements in translating these biomaterials and devices into clinical applications for tissue regeneration and vascular repair.

Moderators:

Monica Moya, Lawrence Livermore National Laboratory
Chris Bashur, Florida Institute of Technology
Bin Jiang, Northwestern University

Objectives

  • 1:00 PM. 1. Modulating Sympathetic Nerve Regeneration for Vascular Remodeling in Peripheral Vascular Grafts. Taylor Brown1, Jessica Li1, Evi Liu1, Ananya Shivakumar1, Caitlyn Dang1, Calvin Chao, M.D.2, Bin Jiang, Ph.D.1 1Northwestern University, 2Feinberg School of Medicine, Northwestern University

  • 1:15 PM. 2. Engineering Mesenchymal Stem Cell-Only Small Artery Scale Vascular Grafts and Branched Vasculature of Varying Geometries through 3D Bioprinting. Katherine Knowles1, Andre Figueroa-Milla, Ph.D.2, Derrick Wells1, Andrew Putnam, Ph.D.3, Marsha Rolle, Ph.D.4, Eben Alsberg1 1University of Illinois at Chicago, 2Worcester Polytechnic Institute, 3University of Michigan, 4The Roux Institute at Northeastern University

  • 1:30 PM. 3. Sacrificial Alginate Microfibers for Enhancing Vasculogenic Assembly in Dense Hydrogels. Firaol Midekssa, MS1, Maggie Jewett1, Elizabeth Stanley1, Megan Wieger1, Kaylin Hanna1, Brendon Baker, Ph.D.1 1University of Michigan

  • 1:45 PM. 4. PEG-Collagen Interpenetrating Networks Support Enhanced Vasculogenesis. Atticus McCoy1, Jordyn Novick1, Darcy Jew1, Andrew Putnam, Ph.D.1 1University of Michigan

  • 2:00 PM. 5. Peptide-PEG DSPE Coatings for Targeted Mitochondria Delivery to the Vascular Endothelium. Brandon Applewhite, Ph.D.1, kaijie Zhang, M.D.2, Aurea del Carmen, B.S.2, Bowen Wang, Ph.D.2, Bin Jiang, Ph.D.1, Natalia matiuto, B.S.2 1Northwestern University, 2Northwestern University Feinberg School of Medicine

  • 2:15 PM. 6. Deciphering Neutrophil Dynamics: Enhanced Phagocytosis of Elastic Particles and Impact on Vascular Targeted Carrier Performance. Oluwaseun Akanbi1, Jonathan Lee1, Valentina Guevara1, Lola Eniola-Adefeso2, Daniel Kupor1, Emma Brannon1, Damon Hoff1 1University of Michigan, 2University of Chicago, Illinois

1C: Dental/Craniofacial Biomaterials SIG 1

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: BLVD C
Session Type: General Session

Description

The Dental/Craniofacial Biomaterials Special Interest Group focuses on basic, applied, and clinical biomaterials research using approaches ranging from synthetic materials to biological mechanisms of therapy, and including materials/biological constructs and tissue structure-function analyses as biomimetic/design bases. Each of these approaches converge into the larger objective of restoring oral tissue structure and function. Issues related to materials used or having potential for use intra-orally or extra-orally for the restoration, fixation, replacement, or regeneration of hard and soft tissues in and about the oral cavity and craniofacial region are included. New dental biomaterials technologies include advanced inorganic and organic materials, biomimetics, smart materials, tissue engineering, drug delivery strategies and surface modified materials.

Moderators:

Daniel Harrington, The University of Texas Health Science Center at Houston
Santiago Orrego, Temple University
Masoumah S. Qaw, University of Maryland-Baltimore

Objectives

  • 1:00 PM. 7. Effect of pore size and dose of BMP-functionalized β-tricalcium phosphate scaffolds on osteogenesis and bone regeneration of critical-size femoral defects in rabbits. Natalie neissen1, Christian Müller-Mai2, Herbert Jennissen3, Markus Laub3, Kirsten Zurlinden3, Horst Fischer4, Christine Knabe1 1Philipps University Marburg, 2Hospital for Special Surgery Luenen, 3University of Duisburg Essen, 4RWTH Aachen

  • 1:15 PM. 8. Conditional Knockout of Agrin in Osteocytes Compromises Bone Homeostasis and Titanium Osseointegration. Maria Gomes1, Leticia Adolpho1, Alann Souza1, Rayana Bighetti-Trevisan1, Robson Calixto1, Fabiola Oliveira1, Adriana Almeida1, Ana Ramos1, Gustavo Garlet1, Adalberto Rosa1, Marcio Beloti1 1University of São Paulo

  • 1:30 PM. 9. Comparison of Fatty Acid-Modified Electrospun Chitosan Membrane for Guided Bone Regeneration as Compared to a Collagen Membrane in a Porcine Mandibular Defect Model. Joel D Bumgardner1, Samarth VeDante2, James Pledger, DDS3, Brett Wilson, DDS3, Anastastios Karydis, DDS3, Franklin Garcia-Godoy, DDS3, K Mark Anderson, DDS3, Joseph Egbodo, none2, Edmara TP Bergamo, DDS4, Lukasz Witek, PhD4 1University of Memphis, 2The University of Memphis, 3UTHSC, 4NYU Dentistry

  • 1:45 PM. 10. Engineering Alpha-Ketoglutarate for Craniofacial Bone Regeneration. Hongli Sun1 1University of Iowa

  • 2:00 PM. 11. Shape Memory Polymer (SMP) Bioglass Composite Scaffolds Designed to Heal Complex Bone Defects. Brandon Nitschke1, Elizabeth Butchko1, MaryGrace Wahby1, Kaylee Breining1, Alexander Konz1, Melissa Grunlan, Ph.D.1 1Texas A&M University

  • 2:15 PM. 12. Manganese Dioxide Nanoparticles Enhance the Osteogenesis of Porous β-tricalcium Phosphate Scaffolds. Yunqing Kang, Ph.D1 1Florida Atlantic University

1D: Fibrous Biomaterials in Tissue Engineering

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: BLVD A
Session Type: General Session

Description

Fibrous biomaterials represent a dynamic and rapidly evolving field at the intersection of materials science, biology, and engineering, dedicated to developing innovative solutions for complex medical challenges. From traditional bandages and gauzes to advanced vascular grafts, tendon patches, drug delivery systems, and tissue engineering scaffolds, fibrous biomaterials have revolutionized various aspects of medical treatment and procedures. This session will highlight the design, fabrication, characterization and use of fibrous biomaterials for use in tissue engineering and regenerative medicine applications.

Moderators:

Jessica Gluck, North Carolina State University
Fan Zhang, University of Washington
Yihan Huang, Cook Medical

Objectives

  • 1:00 PM. 13. Aligned Hyaluronic Acid-Coated Polycaprolactone Composite Scaffolds for Muscle Tissue Repair. Alycia Galindo, B.S.1, Alyssa Chi2, Ruchi Sharma, Ph.D.1, Ievgenii Liashenko, Ph.D.2, Kelly O'Neill, M.S.1, Jenna Khachatourian, B.S.2, Paul Dalton2, Marian Hettiaratchi, PhD2 1University of Oregon Knight Campus, 2University of Oregon

  • 1:15 PM. 14. Fiber-reinforced Extracellular Matrix Mimicking Scaffolds for Tissue Engineering and Regenerative Medicine. Mengnan Dennis, Doctorate Degree1, Martin King2, Jessica Gluck2 1North Carolina State University, 2NC state university

  • 1:30 PM. 15. Locale of Calcium Carbonate Nucleation Among Nonwoven Hemp Organic-Inorganic Composites for Bone Scaffolding. HAJARA BABAYO, Ph.D. Candidate in Fiber and Polymer Science1, Ericka Ford1 1North Carolina state university

  • 1:45 PM. 16. Nanoscale Porosity-Controlled Release from Sintered Electrospun Polycaprolactone and Polyethylene Terephthalate. Francisco Chaparro1, Kayla Presley2, Marco Coutinho da Silva2, Nayan Mandan2, Matthew Colachis2, Christa Moraes2, Hannah Lacy1, John Lannutti2 1Nanoscience Instruments, 2The Ohio State University

  • 2:00 PM. 17. Sodium hydroxide surface treatment of electrospun poly(ε-caprolactone) scaffolds to drive chondrogenesis. Elisa Bissacco, MSc in Biomedical Engineering1, Apoorv Singh, B.Sc. (Materials Science & Engineering)1, Stephen Ferguson, Prof. Dr.1 1Institute for Biomechanics, ETH Zürich

  • 2:15 PM. 18. Synthetic Matrix Fibers Promote 3D Microvascular Assembly, and Host Integration of Endothelial Monocultures in Absentia of Direct Integrin-Mediated Adhesion. Firaol Midekssa, MS1, Christopher Davidson, Ph.D.1, Megan Wieger1, Jordan Kamen1, Andrew Putnam, Ph.D.1, Ariella Shikanov, Ph.D.1, Brendon Baker, Ph.D.1 1University of Michigan

1E: Immune Biomechanics & Mechanobiology

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: 4C
Session Type: General Session

Description

Evidence is emerging that the immune cells respond to the mechanical properties of their microenvironment and this can modulate their function and activation. This session will focus on immune cell interactions with biomaterials and tissues in the context of biomechanics, how this is used to modulate immune function, and how this affects immune tissue models we build.

Moderators:

Bethany Almeida, Clarkson University

Objectives

  • 1:00 PM. 19. Engineering Immunomodulatory Biomaterials for Modulating Macrophage-Mediated Fibrosis in Fracture Nonunion. Matthew Patrick, BS1, Ramkumar Annamalai1 1University at Buffalo

  • 1:15 PM. 20. Piezo1 Mediates Shear-Stress-Induced Signal Two in NLRP3 Inflammasome Activation. Adam Fish1, James Forster1, Vaishali Malik1, Ashish Kulkarni1 1University of Massachusetts Amherst

  • 1:30 PM. 21. Mechanical forces at Immune Synapse Regulate Therapeutic Response in Diffuse Large B Cell Lymphoma. Deepali Balasubramani1, Stefano Travaglino1, Hyun-Kyu Choi, PhD1, Cheng Zhu, PhD1, Ankur Singh, PhD1 1Georgia Institute of Technology

  • 1:45 PM. 22. Studying and Targeting Macrophage Mechanics on Earth and in Space. Meenal Datta, PhD1, Alice Burchett, B.S.1 1University of Notre Dame

  • 2:00 PM. 23. Extracellular matrix damage modulates inflammatory response in fibroblasts through mechanotransductive pathways. Alisa Isaac, PhD1, Teja Guda2, Ope Sanyaolu1, Victoria Garza1 1UTSA, 2The University of Texas at San Antonio

  • 2:15 PM. 24. Sliding hydrogels reveal that modulation of mechanosensing attenuates the inflammatory phenotype of osteoarthritic chondrocytes in 3D. Manish Ayushman1, Hung-Pang Lee, Ph.D.2, Pranay Agarwal, Ph.D.2, Georgios Mikos2, Xinming Tong, Ph.D.1, Sarah Jones1, Sauradeep Sinha, Ph.D.1, Stuart Goodman, MD/PhD1, Nidhi Bhutani, Ph.D.1, Fan Yang, Ph.D.1 1Stanford University, 2Stanford

1F: Microfluidics and Biomaterials for Engineering 3D In Vitro Models

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: Marquette
Session Type: General Session

Description

This session aims to explore the cutting-edge intersection of microfluidic technologies and biomaterials in the development of advanced three-dimensional (3D) in vitro models. As traditional 2D cultures fail to accurately mimic the complexity of tissues, organs, and their in vivo microenvironment, this session will explore how emerging techniques including microfluidics and organoids can be integrated with biomaterials to recreate the dynamic physiological conditions essential for accurate disease modeling, drug testing, and overall phenomena understanding. Topics will include innovations in 3D biomaterial design, the role of microfluidics in both manipulating materials for biofabrication as well as interconnecting complex on-chip cellular microenvironments, organoids, and the application of these systems in tissue engineering, cancer research, and organ-on-chip platforms. A discussion on the challenges and future directions in scaling these models for high-throughput screening and personalized medicine is to be expected.

Moderators:

Carlos Ferreira Guimaraes, University of Minho

Objectives

  • 1:30 PM. 26. High-throughput buoyancy-driven microgel production for simple user interfacing. Durante Pioche-Lee1, Xiaoqian Wang1, Yoke Qi Ho1, Wahidur Rahman1, Armen Vartanian1, Sasha Cai Lesher-Pérez2 1University of Michigan, 2Univeristy of Michigan

  • 1:45 PM. 27. Microfluidic Hydrogel Biofabrication of Miniaturized 3D Cellular Architectures for Cancer Modeling. Carlos Guimarães1, Luca Gasperini1, Ramón Silva1, Rui Reis1 1University of Minho

  • 2:00 PM. 28. Engineered curvature directs matrix deposition during jamming and unjamming transitions. Avinava Roy, M.S.E1, Katherine Wei, B.S1, Max Shtein, Ph.D1, Claudia Loebel, M.D., Ph.D.1 1University of Michigan

  • 2:15 PM. 29. Myofibroblast De-differentiation and Fibrotic Tissue Reversion in a Synthetic 3D Interstitial Matrix. Jingyi Xia1, arjun Gupta1, Ethan poupard1, Vincent Fiore, PhD2, Brendon Baker, Ph.D.1, Daniel Matera3 1University of michigan, 2Boehringer Ingelheim, 3Draper

Speakers

1G: Nanomaterials for Immune Modulation

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: Joliet
Session Type: General Session

Description

Nanomaterials for Immune Modulation: Nanomaterials can be modified to target specialized biomolecules, cells and tissues of the immune system. These nanomaterials range from chemically modified macromolecules, peptides, proteins, or other similar materials. This session will focus on developing nanomaterials that modulate immune responses for a range of diseases.

Moderators:

Adam Gormley, Rutgers University
Lisa Volpatti, Northwestern
Emily Henrich, Rice University

Objectives

  • 1:00 PM. 30. Engineered immunomodulatory nanocarriers for localized tolerance induction in allogeneic islet transplantation. John-Paul Pham1, Layla Summers1, María Coronel1 1University of Michigan

  • 1:15 PM. 31. Systemic Trafficking of mRNA Lipid Nanoparticle Vaccine Following Intramuscular Injection Leads to Generation of Tissue-specific T Cell Responses. Christine Wei, B.S.1, Yining Zhu, M.S.E.1, Xiaoya Lu, M.S.E.1, Kailei Ding1, Hai-Quan Mao, Ph.D.1 1Johns Hopkins University

  • 1:30 PM. 32. Lipid nanoparticle-mediated metabolic reprogramming of dendritic cells for mRNA vaccines. Dongyoon Kim, Ph.D.1, Emily Han, BS1, Michael Mitchell, Ph.D.1 1University of Pennsylvania

  • 1:45 PM. 33. 2D Nanosilicates Loaded with Protein Antigens Enhance Immune Responses. Chih-Yun Liu1, Mark Gibson1, Anirban Das1, Jai Rudra, PhD2, Akhilesh Gaharwar3 1Washington University in St. Louis, 2Washington University in Saint Louis, 3Texas A&M University

  • 2:00 PM. 34. REGvac 2.0: A Microparticle Strategy for Rheumatoid Arthritis Immunotherapy. Jamal Lewis, Ph.D.1, Allen Tu, PhD1 1University of Florida

  • 2:15 PM. 35. Tissue-, cell-, and organelle-specific drug delivery by poly-glucose nanoparticles for cancer immunotherapy. Biplab Sarkar, PhD1, Christopher Rodell, Ph.D.1 1Drexel University

1H: Ophthalmic Biomaterials SIG ( Innovative Biomaterials for Advanced Ophthalmic Solutions: Bridging Research and Clinical Practice)

Date: Wednesday, April 9, 2025
Time: 1:00 PM to 2:30 PM
Room: 4D
Session Type: General Session

Description

Biomaterials often work in more than one application. In this rapid fire session, researchers are encouraged to pitch how their current projects outside of ophthalmology could be used in ophthalmology. Our goal is to forge new ideas that are outside of the box, encouraging researchers to consider how ophthalmology could fit into their projects.

Moderators:

Katelyn Swindle-Reilly, The Ohio State University
Nasif Mahmood, North Carolina State University

Objectives

  • 1:00 PM. 37. Killing Two Birds with One Stone: A Dual-Functional Nanoparticle Formulation for Glaucoma Therapy. Lei Xu1, Lin Qi1, Dong Liu2, Mu Li2, Yang Hu2, Hu Yang1, Vimalin Jeyalatha Mani1, Tzu-Chen Wang1, Da Huang3, Honglan Shi1 1Missouri University of Science and Technology, 2Stanford University School of Medicine, 3Fuzhou University:

  • 1:15 PM. 38. Anti-fouling and Antibacterial Hydrogels for Stimulating Orbital Tissue Expansion in Microphthalmia Patients. Stephanie Fung, PhD1, Matthew Aronson, Mr.2, William Katowitz, MD1, James Katowitz, MD1, Riccardo Gottardi, Dovtort2 1Children's Hospital of Philadelphia, 2University of Pennsylvania

  • 1:30 PM. 39. FRESH 3D Bioprinting of Aligned Human Corneal Stromal Tissue Constructs. Shubhangi Sathyakumar, M.S.1, Yiqin Du, M.D., Ph.D.2, Adam Feinberg, Ph.D.1 1Carnegie Mellon University, 2University of South Florida

  • 1:45 PM. 40. Multi-functional Ionic Liquid: A Novel Approach to Glaucoma Therapy. Hu Yang1, Ashish Trital1, Vimalin Jeyalatha Mani1, Tzu-Chen Wang1, Lin Qi1, Lei Xu1 1Missouri University of Science and Technology

  • 2:00 PM. 41. In Vivo Assessment of an Antioxidant Hydrogel Vitreous Substitute. Katelyn Swindle-Reilly, PhD1, Megan Allyn, MS1, Annie Ryan, MS1, Grace Rivera1, Esther Mamo, BS1, Joshua Bopp, BS1, Sebastian Martinez Hernandez1, Julie Racine, PhD1, Eric Miller, DVM, MS1, Heather Chandler, PhD1 1The Ohio State University

  • 2:15 PM. 42. Surface Functionalized Electrospun Synthetic Scaffold as Carrier for Limbal Stem Cells Derived from Induced Pluripotent Stem Cells for Ocular Surface Regeneration.Nasif Mahmood1, Mohamed R Eletmany1, Ummay Mowshome Jahan1, Sarah Gullion1, Ahmed El-Shafei1, Brian C. Gilger1, Jessica Gluck1 1NC State University