4A: PANEL: Breaking Into Women’s Health Research with Biomaterials Technologies

4B: Antimicrobial Biomaterials 2

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: BLVD C
Session Type: General Session

Description

Due to the threat of antibiotic resistance, biofilms, and the risk of implant-associated infections, strategies for pathogen inactivation play an increasingly important role in biomaterials development. Antimicrobial biomaterials, drug delivery systems, and surfaces that eradicate biofilms and prevent biofilm formation can prevent implant failure, improve clinical outcomes, and reduce treatment costs. This session will cover topics related to designing and characterizing biomaterials to control bacterial, viral, and/or fungal responses. Topics relating to the study of biocompatibility of pathogen-resistant surfaces; the selection and use of in vitro and preclinical models of infection; understanding the roles of biomaterials, pathogens, and hosts in biomaterial-associated infections; and the use of the One Health approach to design biomaterials to combat infections that negatively impact human, animal, and environmental health are also invited.

Moderators:

Elizabeth Brisbois, University of Georgia
Zhaowei Jiang, Brown Univeristy
Bingyun Li, West Virginia University

Objectives

  • 1:30 PM. 140. Interrogating Temperature-Modulated Internal Cavitation Effect on Biofilm Removal Using Self-Propelling Antimicrobial Microbubblers.Joo Hun Lee1, Yujin Ahn1, Adam Marcowicz1, Guillermo Monroy1, Stephen Boppart1, Hyunjoon Kong1 1University of Illinois at Urbana-Champaign

  • 1:45 PM. 141. Development of a Nitric Oxide-Releasing Cephalexin-based Hybrid Compound for Enhanced Antimicrobial Efficacy and Biofilm Disruption.SUMIT KUMAR1, Myddelton parker1, Yi Wu2, Hitesh Handa2, Elizabeth J. Brisbois2 1Universiry of Georgia, 2University of Georgia

  • 2:00 PM. 142. Development of an Antimicrobial Bacteriocin-Based Hydrogel for Treating Second-Degree Burns Wounds.Darnell Campbell, B.S.1, Nicole Levi, PhD1 1Wake Forest University School of Medicine

  • 2:15 PM. 143. Dual-Action Prevention of Adherent and Non-Adherent Biofouling via Slippery, Nitric Oxide-Releasing Nanoemulsion-Infused Porous Surfaces.Grace Nguyen1, Aasma Sapkota1, Hitesh Handa1, Elizabeth J. Brisbois1 1University of Georgia

  • 2:30 PM. 144. Metal-Siloxanes Derived Bio-inspired Superhydrophobicity and Nitric Oxide Generation for Antibiofouling Clinical Applications.Annalise Tucker1, Ekrem Ozkan, PhD1, Sarah Wilson1, Arpita Shome, PhD1, Hitesh Handa1, Elizabeth J. Brisbois1 1University of Georgia

  • 2:45 PM. 145. Harnessing nature’s blueprints to design antifouling antimicrobial interactive biointerfaces and synthetic cells.César Rodriguez-Emmenegger1 1Institute for Bioengineering of Catalonia and Catalan Institution for Research and Advanced Studies

  • 3:00 PM. 146. Nanostructured materials as a tool in the fight against hospital-acquired infections.Anna Michalicha1, Karolina Budniak2, Przemyslaw Suchecki2, Michael Kerber3, Malgorzata Lewandowska2, Anna Belcarz1, Agnieszka Krawczynska2 1Medical University of Lublin, 2Warsaw University of Technology, 3University of Vienna

  • 3:15 PM. 147. Antimicrobial Hemostatic Shape Memory Polymer Foams for Infection Prevention in Traumatic Wounds.Ernest Obeng1, Sevde Can1, Nghia Le Ba Thai1, Changling Du2, Katheryn Dong1, Michaela Hall3, Joshua Satalin3, Michaela Kollisch-Singule3, Mary Beth Monroe, PhD2 1BioInspired Syracuse, Syracuse University, 2Syracuse University, 3SUNY Upstate Medical University

4C: Biomaterials in Biomedicine: Diagnostics, Therapeutics, and Wound Care 2

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: BLVD A
Session Type: General Session

Description

This session highlights recent advances in biomaterials for therapeutics, diagnostics, and biodevices focusing on hemostasis, thrombosis, mechanobiology, and wound healing. Addressing these complex injuries necessitates advanced therapeutic strategies that promote hemostasis, manage infections and wound healing, and provide tissue regeneration. Current treatments for high-energy trauma are inadequate for addressing the extensive tissue damage and infections often associated with these injuries. Through this symposium, we seek to demonstrate the significant clinical potential of problem-focused therapy as a rational solution for improving healing outcomes, rapid and effective tissue regeneration, and robust infection control, leading to improved quality of life for both military personnel and civilians.

Objectives

  • 1:30 PM. 148. Minimally–Invasive Implants to Predict Immunotherapy Sensitivity and Map Organ Allograft Tolerance Trajectories.Russell Urie, PhD1, Amogh Angadi1, Hailey Brady1, Jiane Feng1, Bryan Wonski1, Lonnie Shea1 1University of Michigan

  • 1:45 PM. 149. Immunoregulatory matrix-bound nanovesicles improve mesh-aided abdominal hernia repair.Zhengni Liu, /1, Lei Liu, /2, Beili Zhang, /3, Rui Tang, /2 1The University of Queensland, Brisbane, 2Shanghai East Hospital, TongJi University, 3Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine

  • 2:00 PM. 150. Novel silicone-based sponge for hemostatic treatment: Spatiotemporal studies using a noninvasive model.KAUSIK MUKHOPADHYAY, Faculty1 1University of Central Florida

  • 2:15 PM. 151. Injectable and biodegradable piezoelectric hydrogel for osteoarthritis treatment.I'jaaz Muhammad, B.S.E, MS.E1, Gang Ge, PhD1, Thanh Nguyen, PhD1 1University of Connecticut

  • 2:30 PM. 152. Fibrin Nanoparticle-Driven Gel Formation on Structural Scaffolds for Enhanced Diabetic Wound Healing.Nooshin Zandi, Ph.D.1, Connor Moore, Not Applicable2, Mengnan Dennis, Doctorate Degree3, Martin King, Ph.D.2, Michel Daniele, Ph.D.2, Ashley Brown, PhD3 1UNC-NCSU, 2NCSU, 3North Carolina State University

  • 2:45 PM. 153. Deoxycholate-based Composite Microparticles for Effective and Safe Adipocytolysis.Daniel Kupor1, Michael Felder1, Hanieh Safari, PhD1, Lola Eniola-Adefeso2 1University of Michigan, 2University of Chicago, Illinois

  • 3:00 PM. 154. Emerging Forms of Electrospun Nanofiber Materials for Biomedical Applications.Jingwei Xie1 1UNMC

  • 3:15 PM. 155. Hybrid-nested microneedle arrays integrated with cryogels for effective management of biofilm-infected diabetic wounds.SYED MUNTAZIR ANDRABI1 1University of Nebraska Medical Center

4D: Drug Delivery SIG 2

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: Marquette
Session Type: General Session

Description

This session will survey the diverse range of contemporary drug delivery systems and innovations. Drug delivering biomaterials can include nanoparticles, hydrogels, nanofibers, cell and virus-derived particles, or bioconjugates. Payloads can include DNA, RNA, antibodies, recombinant proteins, or small molecules. Disease applications can range from neurodegeneration to autoimmune disease, trauma, infection, or cancer. Work at all scales, from basic formulation science through therapeutic application in disease models is welcome. Studies that critically evaluate the impact of injection route on treatment efficacy and/or use novel imaging modalities to evaluate drug delivery performance are especially encouraged.

Moderators:

Gopal Agarwal, University of Florida
Lisa Volpatti, Northwestern University

Objectives

  • 1:30 PM. 158. Epigenetic-targeting nanotherapeutics for genetic kidney disease.Joshua Giblin, B.S.1, Eunji Chung, PhD1 1University of Southern California

  • 1:45 PM. 159. Controlled drug delivery with peptide hydrogel enabled with boronic acid dynamic covalent chemistry.Chaoyang Tang1, Brett Pogostin2, Samuel Wu1, Christopher Pennington1, Michael Swierczynski1, Dilrasbonu Vohidova1, Omid Veiseh1, Zachary Ball1, Jeffrey Hartgerink, Ph.D.1, Kevin McHugh, Ph.D.1 1Rice University, 2MIT

  • 2:00 PM. 160. Targeted Lipid Nanoparticle Delivery for Dual RNA-Mediated Treatment of Obesity.William Stewart1, Xiaoyang Xu1, Fengqiao Li2 1New Jersey Institute of Technology, 2New Jersey Institue of Technology

  • 2:15 PM. 161. Engineering CSF pH and tonicity for improved CNS nanoparticle and drug delivery.Constance Mietus, MD, PhD1, Olivia Mihalek2, Elena Andreyko, PhD2, Tobi Babayemi3, Rachael Sirianni, PhD2 1University of Massachusetts, 2UMass Chan Medical School, 3Rice University

  • 2:30 PM. 162. A Scalable, Translatable Hydrogel Platform for Improving Subunit Vaccines.Priya Ganesh1, Alexander Prossnitz, PhD1, Carolyn Jons, M.S.1, Ye Eun Song, M.S.1, Noah Eckman, M.S.1, Eric Appel, PhD1 1Stanford University

  • 2:45 PM. 163. Microneedle Patches for Minimally-Invasive Transdermal Nanoparticle Delivery.Haylee Wagner1, Tailynn McCarty1, Theo Prachyathipsakul1, Minelise Rivera De Jesus1, S. Thai Thayumanavan1, Cathal Kearney1 1University of Massachusetts Amherst

  • 3:00 PM. 164. Urease-Powered Nanomotor Containing STING Agonist for Bladder Cancer Immunotherapy.Sei Kwang Hahn1, Hyunsik Choi1 1POSTECH

  • 3:15 PM. 165. Enhancing Cell Transfection Efficiency via Modulation of Extracellular Fluid Viscosity.Yining Zhu1, Jingyao Ma1, Jiayuan Kong1, Di Yu1, Hai-Quan Mao1 1Johns Hopkins University

4E: Orthopaedic Biomaterials SIG 1

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: 4D
Session Type: General Session

Description

There are increasing demands for orthopedic biomaterials which play critical roles in patient care. This session invites presentations on metals, ceramics, and polymers that are used every day in modern orthopedic applications. Particular focuses will include octacalcium phosphates, bioabsorbable metallic materials, biomaterial degradation and impacts, and additive manufacturing. Applications will span across orthopedic, cardiovascular, craniomaxillofacial implants, etc. In vitro, in vivo, and in silico studies, as well as studies focusing on commercialization and clinical/translational challenges are welcome.

Moderator:

J. Amber Jennings, University of Memphis

Objectives

  • 2:00 PM. 166. Self-Polymerizing, Radio-opaque Resin for Vertebral Augmentation.Russell Thompson, MD, PhD1, Maddison Segal, BS1, Stephanie Sipics, BS1, Matthew Becker, Dr.1 1Duke University

  • 2:15 PM. 167. Bioresorbable Magnesium-Doped Glass-Ceramic Nanoparticle for Osteoimmunomodulation.Sun Latt1, Pedram Sotoudeh Bagha, Ph.D.1, Valeria Cardenas1, Andres Larraza1, Mehdi Razavi, Ph.D.1 1University of Central Florida

  • 2:30 PM. 168. Directing the Matrix-Producing Phenotypic Range of Meniscal Fibrochondrocytes with Biomaterial Composition.Saitheja Pucha1, Kyley Burkey2, Jenny Robinson, PhD, Texas A&M University2, Jay M Patel3 1Emory University, 2University of Washington, 3Emory

  • 2:45 PM. 169. Faster Bone Replacement Achieved by Carbonate Apatite Cement and Granules.Kunio ISHIKAWA, PhD1 1Kyushu University

  • 3:00 PM. 170. The implantation of a proprietary glass polyalkenoate cement into rat subcutaneous tissue.Daniella Marx, PhD1, Sunjeev Phull, PhD2, Marcello Papini, PhD1, Mark Towler, PhD3 1Toronto Metropolitan University, 2University of Missouri Science and Technology, 3Missouri University of Science and Technology

  • 3:15 PM. 171. In vivo wear of highly crosslinked polyethylene in total hip replacements from two manufacturers.Valerio Porrati, BS1, Peter Wahl, MD2, Michel Schläppi, PhD3, Roman Heuberger, PhD4, Deborah Hall, PhD1, Robin Pourzal, PhD1 1Rush University Medical Center, 2University of Bern, 3Kantonsspital Winterthur, 4RMS Foundation

  • 1:30 PM. 172. Osteoinductive Chitosan Hydrogel for Vertebral Compression Fracture Repair Using an Osteoporotic Rabbit Model.August Hemmerla, Bachelors of Science1, Abigail Grisolano2, Austin Kimes, DVM2, Sam Huddleston, PhD2, John Wray, DVM2, Shwetha Ramachandra, MS2, Farnoush Rezaei, MS2, Don Moore, MD2, Ji-Hey Lim, DVM, PhD, DACVIM3, Bret Ulery, Ph.D.4 1University of Missouri, 2University of Missouri – Columbia, 3University of California, Davis, 4University of Missouri - Columbia

  • 1:45 PM. 173. Photocurrent-Directed Immunoregulation Accelerates Osseointegration through Activating Calcium Influx in Macrophages.Yizhou Zhu, PhD1, Kelvin Yeung, PhD1 1The University of Hong Kong

4F: Regenerative Biomaterials for Complex Tissue Regeneration 1

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: BLVD B
Session Type: General Session

Description

This symposium will focus on the most recent advances in the design of regenerative biomaterials for engineering challenging tissues and organs. From pancreas to liver and spinal cord, approaches including functional materials, 3D-bioprinting, gene therapy, and nanomaterials, among many others, will be included. We will highlight the recent trends in the development of functional biomaterials that play active role in controlling cellular behavior and complex tissue regeneration. We will cover different classes of biomaterials including the ones that can direct cell fate and promote differentiation. Translational strategies for taking these biomaterials from bench to bedside will also be discussed. Significant international contributions will be selected to facilitate fruitful discussions aiming to progress the advance of the field and to assist the generation of new productive and multidisciplinary collaborations.

Moderators:

Gulden CamciUnal, Univeristy of Massachusetts Lowell
Woojin Han, Icahn School of Medicine at Mount Sinai
Jian Yang, Westlake Univeristy
Guillermo Ameer, Northwestern University

Objectives

  • 2:00 PM. 183. Millimeter-scale Dual-Opposing RNAi Gradient Hydrogel for Interfacial Gene Silencing.Cong Huynh1, Tyler Hoffman2, Marcus Goudie2, Peyton Tebon2, Minh K. Nguyen3, Kaelyn L. Gasvoda1, Yang Song2, Hyojin Ko2, Kirsten Fetah2, Ali Khademhosseini2, Song Li2, Eben Alsberg1 1University of Illinois at Chicago, 2University of California Los Angeles, 3Case Western Reserve University

  • 2:15 PM. 184. Sustained RNAi Molecule Presentation in Hydrogels Destabilizes Local Actin Polymerization of Encapsulated Cells to Induce Spatiotemporal Shape Transformations.Kaelyn L. Gasvoda1, Aixiang Ding1, Cong Huynh1, Oju Jeon1, Alexandria Sterenberg1, Eben Alsberg1 1University of Illinois at Chicago

  • 2:30 PM. 185. Citrate-based micropillar scaffolds promoted bone regeneration via regulation of cell secretome.Xinlong Wang1, Yiming Li1, Yuan Luo1, Guillermo Ameer1 1Northwestern University

  • 2:45 PM. 186. Regenerative features in chronic paralyzed rats implanted with 3D reduced graphene oxide foams.Esther Benayas1, Raquel Madroñero2, Ana Domínguez-Bajo1, Yasmina Hernández-Martín3, Marta Zaforas2, Juan Aguilar2, Elisa López-Dolado2, María Serrano1 1Consejo Superior de Investigaciones Científicas, 2Hospital Nacional de Parapléjicos, 3Hospital Nacional de Paraplégicos

  • 3:00 PM. 187. Magnesium ions-incorporating bioactive hydrogels for in situ tissue regeneration.Jeong Min Kim, BS1, Kyung Min Park, Ph.D1 1Incheon National University

  • 3:15 PM. 188. Reprogrammable 4D Tissue Engineering Scaffold via Reversible Ion-Transfer Printing.Aixiang Ding1, Eben Alsberg1 1University of Illinois at Chicago

4G: Tissue Engineering SIG 2

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: Joliet
Session Type: General Session

Description

Tissue Engineering SIG is a forum to exchange information, further knowledge, and promote greater awareness regarding all aspects of the use of biomaterials to engineering tissue substitutes or to promote tissue regeneration. Of primary interest and relevance to TE SIG is the use of appropriate materials (synthetic and natural) with cells (either native or from a donor source) and/or biological response modifiers (e.g., growth factors, cytokines and other recombinant products) to replace tissue and organ functions. Particular emphasis is placed on the development of materials to better incorporate, protect, and deliver both the cells and biological response modifiers to help promote the healing and regenerative processes. The group is committed to forging interactions among basic scientists, applied scientists, engineers, clinicians, industrial members, professional societies in related fields, and regulatory groups in its efforts to expand and effectively utilize the shared knowledge base in this multidisciplinary field.

Moderators:

Jeannine Coburn, Worcester Polytechnic Institute
Gulden CamciUnal, Univeristy of Massachusetts Lowell
Qun Wang, Iowa State University

Objectives

  • 1:30 PM. 189. Amphiregulin releasing alginate hydrogels for treating ischemic muscle injuries.Brennagh Shields1, Lauren Mottel1, Lindsay Gallagher1, Brian Kwee1 1University of Delaware

  • 1:45 PM. 190. Decellularized Lucky Bamboo Scaffolds as Platforms for Bone Tissue Engineering.Ali Salifu1, Precious Etinosa2, Vanessa Uzonwanne1, Joshua Gershlak3, John Obayemi2, Glenn Gaudette1, Wole Soboyejo2 1Boston College, 2Worcester Polytechnic Institute, 3Massachusetts General Hospital

  • 2:00 PM. 191. Hydrogel-Delivery of hiPSC-Cortical Neurons Improves Local and Distal Anatomical and Functional Outcomes Following Chronic Cervical Spinal Cord Injury.Vanessa Doulames, PhD1, Meghan Hefferon, BS1, Neil Baugh1, Christopher Long1, Michelle Huang1, Theo Palmer, PhD2, Sarah Heilshorn, PhD1 1Stanford University, 2Stanford University School of Medicine

  • 2:15 PM. 192. Magneto-Responsive Iron-Chelated Silk Microfibers as an In-Situ Aligning Architecture for Injectable Biomaterials.Melissa Wojnowski, MS1, Jeannine Coburn, PhD1 1Worcester Polytechnic Institute

  • 2:30 PM. 193. Rapid Fabrication of Polyvinyl Alcohol Hydrogel Foams with Encapsulated Mesenchymal Stem Cells for Chronic Wound Treatment.Nghia Le Ba Thai1, Emily Fittante1, Zhen Ma2, Mary Beth Monroe, PhD2 1BioInspired Syracuse, Syracuse University, 2Syracuse University

  • 2:45 PM. 194. Self-organized insulin-producing β-cells differentiated from human omentum-derived stem cells and their in vivo therapeutic potential.Ji Hoon Jeong, Ph.D.1, Yongsung Hwang, Ph.D.1, Joohyun Kim, Ph.D.1, Ki Nam Park, Ph.D.2, Sang-Heon Kim, Ph.D.3, Jae Hong Park, Ph.D.4, Sung Sik Hur, Ph.D.1 1Soonchunhyang institute of medi-bio science, 2Soonchunhyang University Bucheon Hospital, 3Korea Institute of Science and Technology, 4Soonchunhyang University Cheonan Hospital

  • 3:00 PM. 195. Use of an Injectable Recombinant Polypeptide Scaffold for Peripheral Nerve Repair.Rachael Putman1, Stefan Roberts, PhD2, Daniel Joh, MD, PhD1, Neill Li, MD1, Ashutosh Chilkoti, PhD1 1Duke, 2inSoma Bio; Duke

  • 3:15 PM. 196. WNT7A mRNA-LNPs Reduce Skeletal Muscle Fibro-adipogenic Progenitor Adipogenesis.Larion Martin Santiago1, Kasoorelope Oguntuyo1, Britney Chin-Young1, Angelo Amabile, PhD1, Woojin Han1 1Icahn School of Medicine at Mount Sinai

4H: Postdoctoral Recognition Award

Date: Thursday, April 10, 2025
Time: 1:30 PM to 3:30 PM
Room: 4C
Session Type: General Session

Description

Sponsored by Royal Society of Chemistry. The goal of the SFB-PRA is to recognize excellence in future leaders of biomaterials and provide a platform to present their work to faculty and potential recruiters. Finalist will present at the PRA competition and the award recipients will be selected upon the quality and presentation of their work.

Moderators:

Claudia Loebel, University of Michigan
Stephanie Fung,