7A: Biomaterials and Nanotechnology for Cancer Modeling and Theranostics 2

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: Centennial III/IV

Description

Moderators:

Sara Pedron-Haba
Research Assistant Professor
University of Illinois Urbana-Champaign

Vinay Abhyankar, PhD
Assistant Professor
Rochester Institute of Technology

  • 8:00 AM. 340. Morphology Effect of PEGylated Iron Oxide Nanoparticles on the Enhancement of MRI Contrast Signal in Breast Cancer.Juan Beltran-Huarac1 1East Carolina unIVERSITY
  • 8:15 AM. 341. Collagen Fiber Alignment and Internal Architecture Cooperatively Regulate Breast Cancer Cell Migration in a Subtype-Specific Manner.Poorya Esmaili Bambizi1, Indranil M. Joshi, PhD1, Tresa M Elias, PhD2, Edward Brown III, PhD2, Vinay Abhyankar, PhD1 1Rochester Institute of Technology, 2University of Rochester
  • 8:30 AM. 342. Aligned Microfiber Scaffolds for Directed Glioblastoma Cell Migration Assays.Maya Kasteleiner1, Charlotte Olds2, Patrick Hall1, Ievgenii Liashenko, PhD2, Paul Dalton, PhD2, Gabriella Lindberg, PhD1 1Knight Campus, University of Oregon, 2University of Oregon
  • 8:45 AM. 343. Biomaterial-Based Microengineered Tumor Models for Investigating Cancer Cell Invasion.Amir K. Miri, Ph.D.1, Elvan Dogan, Ph.D.1, Ayda Pourmostafa, M.Sc.1, Swaprakash Yogeshwaran, M.Sc.1 1New Jersey Institute of Technology
  • 9:00 AM. 344. Quantitative Evaluation of Nanoparticle Lymphatic Delivery Using Magnetic Particle Imaging.Esteban Bermudez-Berrios1, Hayden Good1, Taylor Shields1, Aniela Nozka1, Neel Eswaran1, Ambar Velazquez-Albino1, Eric Imhoff1, Victor Rivera-Llabres, PhD2, Christiana Shaw, MD MS FACS1, Elizabeth Maxwell, DVM, MS, DACVS-SA, CVPP, FFCP, CVA1, Carlos Rinaldi-Ramos1 1University of Florida, 2University of Illinois Ubana-Champaign
  • 9:15 AM. 345. Magneto-electric Silica Nanocarriers for Doxorubicin Delivery Inhibit Tumor Growth and Reduce Systemic Toxicity in Triple-Negative Breast Cancer.Aurelie Brownsberger, M.S.1, Carlie Kudary1, Ethan Rodriguez, B.S.2, Erin Howe, Ph.D.2, Lili Vajtai1, Bence Markus, Ph.D.1, Simon Ferenc, Ph.D.3, Ryan Roeder, PhD1, Prakash Nallathamby, Ph.D.1 1University of Notre Dame, 2Rosalind Franklin University of Medicine and Science, 3Budapest University of Technology and Economics
  • 9:30 AM. 346. Translational 3D Spheroids for Evaluating Curcumin and Celecoxib in Ovarian Cancer.Chipo Chapusha1, Gautam Ray1, Debarshi Roy2, Amol Janorkar, PhD1 1University of Mississippi Medical Center, 2Alcorn State University
  • 9:45 AM. 347. Towards Reliable Tracking of Natural Killer Cells Using Commercial Iron Oxide Nanoparticles and Magnetic Particle Imaging.Suzanne Lightsey1, Victoria Consalvo1, SK Rajab Ali, PhD1, Daniela Paula Valdes, PhD1, Jeremiah Oyer, PhD2, Alicja Copik, PhD2, Carlos Rinaldi-Ramos1, Blanka Sharma, PhD1 1University of Florida, 2University of Central Florida

7B: Drug Delivery SIG 4: Precision Nanomedicine for Cancer and Inflammatory Disease

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: Centennial I

Description

This session will survey the diverse range of contemporary drug delivery systems and innovations. Drug delivering biomaterials can include nanoparticles, hydrogels, nanofibers, cell and virus-derived particles, or bioconjugates. Payloads can include DNA, RNA, antibodies, recombinant proteins, or small molecules. Disease applications can range from neurodegeneration to autoimmune disease, trauma, infection, or cancer. Work at all scales, from basic formulation science through therapeutic application in disease models is welcome. Studies that critically evaluate the impact of injection route on treatment efficacy and/or use novel imaging modalities to evaluate drug delivery performance are especially encouraged.

Moderators:

John Clegg
Assistant Professor
Gallogly College of Engineering
Peggy and Charles Stephenson
School of Biomeical Engineering
The University of Oklahoma

Cynthia Okafor
The University of Iowa | Office of Innovation

Aliasger Salem, Ph.D
Lyle and Sharon Bighley Endowed Chair & Professor / Associate Vice President for Research
University of Iowa | College of Pharmacy

  • 8:00 AM. 348. A sphingolipid-derived paclitaxel nanovesicle enhances efficacy of combination therapies in triple-negative breast cancer and pancreatic cancer.Jianqin Lu1 1University of arizona
  • 8:15 AM. 349. Engineering Dendrimer Based Platform for PSMA Mediated Drug Delivery of Sorafenib to Prostate Cancer.Ritama Ghosh, WSU ID 118999071, Anunay J Pulukuri1, Rishi Sharma1, Anjali Sharma1 1Washington State University
  • 8:30 AM. 350. Nanoparticle-based dual-drug delivery to BRAF V600E Melanoma.Ramkrishna Sen, PhD1, Mohammad Alnatour, PhD1, L.S.L Janardhanam, PhD1, Md Meraj Anjum, PhD1, Sean M Geary, PhD1, Aliasger Salem, PhD1 1University of Iowa
  • 8:45 AM. 351. Synergistic In Vivo Therapy Using Bioengineered microRNA and Chemotherapy for High-Risk Neuroblastoma.Yu-Rim Ahn, Ph.D.1, Yunyoung Lee, Ph.D.2, Toola Alkhazal, B.S.2, Kathleen Doyle, M.D.2, Meijuan Tu, Ph.D.2, Aming Yu, Ph.D.3, Jinhwan Kim, Ph.D.2, Erin Brown, M.D.2 1Organization* UC Davis Health, University of California, Davis, 2UC Davis Health, University of California, Davis, 3UC Davis Health,University of California, Davis
  • 9:00 AM. 352. Imageable Beads for Targeted Multi-Drug Delivery in Prostate Cancer Chemoembolization.Fatema Jamali, PhD1, Samuel Stealey, PhD1, Hanieh Shokrani, PhD1, Silviya Zustiak, PhD1 1Saint Louis University
  • 9:15 AM. 353. A Long-acting Injectable Nanoparticle System for Sustained Anti-TNF-α Antibody Therapy for Treatment of Ulcerative Colitis.Yicheng Zhang, PhD1, Ling Li, MD PhD2, Jiayuan Kong, PhD1, Yuanmuhuang Long, BS1, Sachin Kammula, BS1, Xiaoya Lu, MS1, Florin Selaru, MD MBA2, Hai-Quan Mao, PhD1 1Johns Hopkins University, 2Johns Hopkins University School of Medicine
  • 9:30 AM. 354. Prebiotic-Trained Gut Postbiotics Reprogram Immunity and Metabolic Homeostasis in Obesity.Dong Kwang Min1 1Sungkyunkwan University
  • 9:45 AM. 355. Drug Repositioning Using Insoluble Fibrinogen.Jun Adan-Kubo, Ph.D., MBA1 1Japan Blood Products Organization

7C: Stimuli-Responsive Biomaterials 1

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM

Description

Materials that respond to environmental stimuli, such as heat, light, pH, or biological signals, provide unique tools for environmentally-responsive and/or temporal changes in biomaterial properties over time. This session will focus on materials, including hybrid materials, that can be stimulated with a variety of physiological and external stimuli to achieve desired outcomes. Research related to the use of stimuli-responsive materials that respond to endogenous or exogenous signals to (1) trigger drug delivery, (2) study and control the cellular response to microenvironmental changes, and/or (3) drive tissue regeneration and disease treatment is of particular interest.

Moderators:

Mary Beth Monroe
Associate Professor, Biomedical Engineering
Texas A&M University

  • 8:00 AM. 356. Active nano-crumpled topographies for long-term antibacterial protection.Mohammad Asadi Tokmedash1, Jouha Min1 1University of Michigan
  • 8:15 AM. 357. Minimal syntactic elements order the stimuli-responsive phase behavior of novel intrinsically disordered proteins.Maria Camila Giraldo-Castaño, B.S.1, Mariell Pascual, B.S.1, Spencer Hayes, M.S.1, Felipe Quiroz, PhD2, Shuo-Lin Weng, B.S.3, Jeetain Mittal, PhD3 1Georgia Institute of Technology & Emory University, 2Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, 3Texas A&M University
  • 8:30 AM. 358. Bioluminescent Hydrogel Sensors Enable Rapid and Continuous Monitoring of Cytokines.Kayle Riley, M.S.E1, Jaselyn Porter1, Nandita Boddu1, Maria Coronel, PhD1 1University of Michigan
  • 8:45 AM. 359. Dual Stage Addition and Photo Crosslinked Hydrogels for Use in Geometrically Tunable Blood Shunts.Akari Seiner, MS1, Elisabeth Posthill, MS1, Lindsay Hager, MS1, Amy Throckmorton, Ph.D.1, Christopher Rodell, Ph.D.1 1Drexel University
  • 9:00 AM. 360. Development of Photoacoustic Nanosensor for the Detection of Granzyme B in Response to Natural Killer Cell Immunotherapy.Brendan Barlow1, Tasneem Mukarrama2, Anika Kulkarni1, Ana Sandoval-Castellanos, PhD2, Myeongsoo Kim3, Robert Canter, M.D.2, Jinhwan Kim, Ph.D.4 1University of California Davis, 2UC Davis, 3Georgia Institute of Technology, 4UC Davis Health, University of California, Davis
  • 9:15 AM. 361. Boolean Logic-based Controlled Release of Therapeutic Proteins from Biomaterials.Cole Deforest, PhD1 1University of Washington
  • 9:30 AM. 362. An N-glycosylation consensus sequence fusion domain drives supramolecular assembly of protein biomaterials.Eric Hill, MS1, Stephen Michel1, Ryan Clark, BS1, Ayumi Shigemoto, PhD1, Natasha Sequeira, BS1, Benjamin Keselowsky, PhD1, Gregory Hudalla, PhD1 1University of Florida
  • 9:45 AM. 363. Combatting MRSA: A Degradable Thiol-ene Platform for pH-Activated Release of Doxycycline.Chipo Chapusha1, Nicholas McGowan1, Paige Smith1, Anthony Hasley1, Mary Carr1, Mary Marquart, PhD1, Jared Cobb2, Amol Janorkar, PhD1 1University of Mississippi Medical Center, 2US Army Corps of Engineers

7D: Granular & Macroporous Biomaterials for Tissue Engineering 2

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: Hanover AB

Description

Granular hydrogel materials emerged as a class of biomaterial that provide for well-defined in vitro and in vivo systems with plug-and-play components and tissue-mimicking 3D environments. Granular hydrogels are composed of a slurry of microgel particles that are assembled to form a larger porous structure. Microporous annealed particle (MAP) scaffolds are a subclass of granular hydrogel material with a void space network stabilized by inter-particle chemical bonds. The modular nature of granular hydrogels offers enormous tunability in not only the individual microgel design but also the homogenous or heterogenous microgel assembly into the bulk scaffold. This session will explore current advances in granular hydrogel technology, including MAP scaffolds, for both immune modulation, tissue repair, organ-on-a-chip, and 3D-printing applications.

Moderators:

Tatiana Segura
Duke University

Donald Griffin
The University of Virginia

  • 8:00 AM. 364. Hyaluronic Acid Granular Hydrogels through Initiator-free Visible Light Mediated Crosslinking.Aina Solsona Pujol1, Keisuke Nakamura2, Jason Burdick, Ph.D.1 1University of Colorado Boulder, 2Kyoto University
  • 8:15 AM. 365. Granular Hydrogel-Based Perivascular Niche Models to Examine Glioblastoma Invasion.Joel Kattoor1, Brittany Payan, B.S.2, Tejasvi Anand, B.S.1, Brendan Harley3 1University of Illinois Urbana-Champaign, 2University of Illinois Urbana Champaign, 3University of Illinois at Urbana Champaign
  • 8:30 AM. 366. Dynamic granular hydrogels as a confinement model to assess pancreatic cancer cell fate.Ellen Frahm1, Chien-Chi Lin, PhD1 1Purdue University
  • 8:45 AM. 367. Controlled Growth Factor Release from Granular Hydrogels for Lymphatic Vessel Formation.Salmady Ramos Valentin1, Daniel Montes Pinzon1, Rananjaya Gamage, PhD1, Donny Hanjaya-Putra1 1University of Notre Dame
  • 9:00 AM. 368. Rheological Exploration of the Role of Microgel Polymer Network Structure and Interparticle Interactions on the Brittility of Granular PEG Hydrogel Biomaterials.Victor Rivera-Llabres, PhD1, Jiye Lee1, John Brownridge1, Simon Rogers, PhD1, Brendan Harley2 1University of Illinois Ubana-Champaign, 2University of Illinois at Urbana Champaign
  • 9:15 AM. 369. Compressive Loading of Alginate Microgel-Spheroid Composite Scaffolds Induces Hypertrophic Chondrocyte Phenotype in Stem Cell Spheroids.David Ramos-Rodriguez1, Andrea Filler1, Sheetal Palle2, Shierly Fok1, Erika Wheeler1, Mason Caserta1, Connor Dorais1, J. Kent Leach1 1UC Davis Health, 2UC Davis
  • 9:30 AM. 370. Filling The Void: Vasculogenic Assembly in Semi-Synthetic Granular Hydrogel Grafts.Michael Hu1, Despina Pavlidis1, Gonzalo Anyosa1, Ariella Shikanov, PhD1, Brendon M. Baker, PhD2 1University of Michigan, 2UNIVERSITY OF MICHIGAN- ANN ARBOR
  • 9:45 AM. 371. Granular Biomaterial Platform Enables Vascularized Subcutaneous Cell Delivery.Jean-Pierre Pierantoni1, John-Paul A. Pham1, Nicole Racca1, Maria Coronel, PhD1 1University of Michigan

7E: Fibrous Biomaterials for Tissue Engineering

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: Hanover CDE

Description

Fibrous biomaterials represent a dynamic and rapidly evolving field at the intersection of materials science, biology, and engineering, dedicated to developing innovative solutions for complex medical challenges. From traditional bandages and gauzes to advanced vascular grafts, tendon patches, drug delivery systems, and tissue engineering scaffolds, fibrous biomaterials have revolutionized various aspects of medical treatment and procedures. This session will highlight the design, fabrication, characterization and use of fibrous biomaterials for use in tissue engineering and regenerative medicine applications.

  • 8:00 AM. 372. Co-Electrospinning of a Multifunctional Bone Wrap from Polycaprolactone and Decellularized Tissue.Madeline Laude1, Sarah Jones, Ph.D.1, Zeenat Oyebanji1, Ruchi Birur1, Andres Luengo Martinez1, Isabelle Gilbert1, Phillip Baek1, Nichole Longbottom2, Nicole McCullough2, Staci Horn, Ph.D.2, Chien-Yu Lin1, Matthew Lohr1, Fred Clubb, Ph.D.2, Manuel Rausch, Ph.D.1, Elizabeth Cosgriff-Hernandez, Ph.D.1 1University of Texas at Austin, 2Texas A&M University
  • 8:15 AM. 373. Foam-Fiber Composite Scaffolds for Tissue Engineering and Regenerative Medicine.Mengnan Dennis, Doctorate Degree1, Jessica Gluck, PhD2, Martin King, PhD2 1North Carolina State University, 2NC State University
  • 8:30 AM. 374. Non-Ionic Surfactant Modifies Electrospun Fiber Properties for In Vitro Fibrous Connective Tissue Models.Katherine Meinhold, B.S.1, Jenny Robinson, Ph.D.1 1University of Washington
  • 8:45 AM. 375. On-Demand Transparency of Aligned Cellulose Nanofiber networks in Collagen Scaffolds for Corneal Bioprinting.Diya Singhal1, Will Salisbury1, Betty Cai1, Neil Baugh1, Carla Huerta-López, PhD1, Seungheon Lee1, David Myung, PhD1, Lucia Brunel, PhD1, Sarah Heilshorn, PhD1 1Stanford University
  • 9:00 AM. 376. Establishing Novel Fluorescent Polydioxanone Microfiber Scaffolds for Tissue Engineering Investigations.Iman von Briesen, M.S.1, Paul Dalton, PhD1, Maya Kasteleiner2, Patrick Hall, M.S.1, Ievgenii Liashenko, PhD1, Ramesh Jasti, PhD1, Harrison Reid, PhD1 1University of Oregon, 2Knight Campus, University of Oregon
  • 9:15 AM. 377. Designer fibrous composites promote integrin-VEGFR crosstalk to enhance angiogenesis and wound healing.Yimeng Zhao, B.S.1 1University of Michigan
  • 9:30 AM. 378. Leveraging Entanglement to Fabricate Injectable and Stable Fibrous Scaffolds.Alexander Favela1, Matthew Davidson, PhD2, Ryan Hayward1, Jason Burdick, Ph.D.3 1University of Colorado, Boulder, 2University of Colorado-Boulder, 3University of Colorado Boulder
  • 9:45 AM. 379. Predicting Simultaneous Strain Stiffening and Nonlinear Stress Relaxation in Fibrous Networks.Dallin Jacobs1, Natalie Zwick1, Truc Dinh2, Aidan Gilchrist, Ph.D.1 1Univeristy of California, Davis, 2University of California, Davis

7F: Tissue Engineering SIG 2

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: Hanover FG

Description

Tissue Engineering SIG is a forum to exchange information, further knowledge, and promote greater awareness regarding all aspects of the use of biomaterials to engineering tissue substitutes or to promote tissue regeneration. Of primary interest and relevance to TE SIG is the use of appropriate materials (synthetic and natural) with cells (either native or from a donor source) and/or biological response modifiers (e.g., growth factors, cytokines and other recombinant products) to replace tissue and organ functions. Particular emphasis is placed on the
development of materials to better incorporate, protect, and deliver both the cells and biological response modifiers to help promote the healing and regenerative processes. This year’s session will also highlight the latest advancements in naturally-derived biomaterials, bioadhesives, and biomaterial membranes for tissue repair and wound healing. The group is committed to forging interactions among basic scientists, applied scientists, engineers, clinicians, industrial members,
professional societies in related fields, and regulatory groups in its efforts to expand and effectively utilize the shared knowledge base in this multidisciplinary field. This session will also include biomaterials-enabled organoid systems and integrated biomaterials and synthetic biology approaches to engineer, model, and regenerate functional tissues.

Moderators:

Dr. Gulden Camci-Unal
Professor | Chemical Engineering, Center for Pathogen Research & Training (CPRT)
UMass Lowell

Scott Taylor
Poly-Med

  • 8:00 AM. 380. Fibrous MAP Hydrogels Coordinate VEGF Signaling to Enhance Vascular Integration for Islet Transplantation.Michael Hu1, Yimeng Zhao, B.S.1, Manuj Bandral, PhD1, David Lorberbaum, PhD1, Brendon M. Baker, PhD2 1University of Michigan, 2UNIVERSITY OF MICHIGAN- ANN ARBOR
  • 8:15 AM. 381. Matrix biophysics regulates early 3D neuroepithelium morphogenesis in vitro.Michelle Huang1, Julien Roth, PhD2, Kristine Pashin1, Sarah Heilshorn, PhD1 1Stanford University, 2Genentech
  • 8:30 AM. 382. Engineering the Degradation of Decellularized Bamboo Scaffolds for Bone Regeneration.Ali Salifu, PhD1, Vanessa Uzonwanne, PhD1, Tom Buckman, BS1, Kathryn Chang, Undergraduate1, Glenn Gaudette, PhD1 1BOSTON COLLEGE
  • 8:45 AM. 383. Plodia interpunctella as a source of Silk Proteins for Nanomaterial Applications.Lauren Eccles, BS1, Bryce Shirk, PhD1, Nikita Patel, BS1, Whitney Stoppel, PhD1 1University of Florida
  • 9:00 AM. 384. Optimization and Characterization of Plant-based Inks for Light-based 3D Printing of Intricate Structures.Luke Ramsier1, Ebrahim Tajik1, Hossein Ravanbakhsh1 1University of Akron
  • 9:15 AM. 385. Interstitium-lymphatic tissue-on-a-chip for engineering sustained release lymphatic nanomedicine.Tae Hee Yoon, M.S.1, Zhanna Nepiyushchikh, Ph.D.1, Maya Levitan, n.s.1, Alexander Heiler1, Guanzhen He1, Brandon Dixon, Ph.D.1, Susan Thomas, Ph.D.1 1Georgia Institute of Technology
  • 9:30 AM. 386. Spatiotemporal Mapping of Tissue Oxygenation Using Implantable Nanosensors.Maedeh Rahimnejad1, John-Paul A. Pham1, Layla M. Summers1, Maria Coronel, PhD1 1University of Michigan
  • 9:45 AM. 387. Engineering a Tunable PEG-4MAL Hydrogel Platform for Patient-Derived Intestinal Enteroid Culture.Luis Arrieta-Viana, Dr.1, Andrés García, PhD2, Tatiana Karakasheva, Dr.3 1Georgia Tech, 2Georgia Institute of Technology, 3Children's Hospital of Philadelphia

7G: Biomaterials for Neural Engineering 2

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: GH East AB

Description

Engineered biomaterials are a centerpiece of new therapeutic approaches to treat neural injury as systems to deliver molecular and cell-based therapies to regenerate neural circuits or as components in closed-loop neurotechnologies. Biomaterials innovations that can improve the delivery of small molecules, biologics or cells to neural tissue, direct neuronal functional states, guide neural circuity connectivity, and improve neural cell interactions with devices hold the key to realizing new effective therapies. Furthermore, engineered biomaterials are uniquely positioned for use in creating, testing, and regenerating neural tissue with applications like in vitro models of injury and disease, brain organoid models, tissue engineering, therapeutic treatments, understanding neural development, and mapping the brain. This session will focus on cutting edge research in neural biomaterials including fundamental materials development work through pre-clinical and clinical studies. These include big questions surrounding understanding and treating neurological diseases and injuries of the peripheral and central nervous systems as well as drug, biologic, and cellular therapy delivery and neural interfacing. This session will be of significant interest to industry, academia, and clinical groups working in a broad array of neural engineering fields.

Moderators:
Michael Gower
Associate Professor | Affiliate faculty in Chemical Engineering
University of South Carolina

Timothy O'Shea
Assistant Professor (BME, MSE)
Boston College | College of Engineering

Kelly Langert, Ph.D
Assistant Professor
Molecular Pharmacology and Neuroscience
Loyola University Chicago, Stritch School of Medicine

  • 8:00 AM. 388. Poly (Maltose - Lactate) Metabolic Copolymers Fuel Neural Progenitor Cell and Astrocytes Proliferation.Kunyu Li, master1, Timothy O'Shea, PhD1 1Boston University
  • 8:15 AM. 389. Off-target fibrotic effects of pro-angiogenic brain-reparative hydrogels and the role of microglia-pericyte crosstalk.Emma Whitehead, B.S.1, Tatiana Segura, PhD1, Katrina Wilson, PhD2, Kevin Erning, PhD3, Nicole Ratterman1 1Duke University, 2KBI BioPharma, 3Biomedical Engineering
  • 8:30 AM. 390. Glycan Modified Biomaterials Support Neurogenesis After Ischemia Stroke.Sanchuan Che1 1Duke University
  • 8:45 AM. 391. Monocyte Membrane Coated Nanoparticles Enable Active Targeting to Nerves in a Model of CMT1X.Harshita Kondeti1, Maleen Cabe, MS1, Kelly Langert, PhD1 1Loyola University Chicago
  • 9:00 AM. 392. A Hyaluronic Acid Hydrogel Multi-spheroid Midbrain Model for Studying Opioid Addiction.Ze Zhong Wang, Ph.D1, Zhan Shu, Ph.D2, Alexander Laperle, Ph.D3, Samantha Santacruz, Ph.D1, Clive Svendsen, Ph.D3, Nigel Maidment, Ph.D2, Stephanie Seidlits, PhD4 1University of Texas Austin, 2University of California, Los Angeles, 3Cedars-Sinai Medical Center, 4University of Texas at Austin
  • 9:15 AM. 393. Multifunctional platelet-like particles modulate inflammation and coagulation in polytrauma-traumatic brain injury.Diana Herrera-Diaz1, Luke Tucker, PhD2, Sierra Chimene, MS1, Amberlyn Simmons, MS1, Gregory Jensen, PhD1, Anastasia Sheridan-Muñana3, Sanika Pandit4, Crystal Willingham1, Ashley Brown, PhD5, Sarah Stabenfeldt, PhD1 1Arizona State University, 2North Carolina State University and The University of North Carolina at Chapel Hill, 3NC State University, 4NC State, 5North Carolina State University
  • 9:30 AM. 394. Activity Based Nanosensor to Interrogate Protease Activity by Cell Type, Region and Sex in Traumatic Brain Injury.Marianne Madias1, Jordan Nichols1, Ester Kwon1 1UCSD
  • 9:45 AM. 395. Engineering a long-lived human neurovascular PENTA culture to model vascular–neuroimmune remodeling after mild and moderate traumatic brain injury.Volha Liaudanskaya1, Daniel Hinrichsen1, Sunghyun Jun1, Sahan Kansakar2, Charitha Anamala1, Mitchell Thielen1 1University of Cincinnati, 2Unviersity of Cincinnati

7H: Biomaterials for In Vitro Models of Disease 2

Date: Saturday, March 28, 2026
Time: 8:00 AM to 10:00 AM
Room: GH East CD

Description

This session is dedicated to biomaterials used in the fabrication of in vitro disease models and will highlight cutting-edge strategies for replicating pathological conditions outside the human body. Topics will include the use of biomaterials in the development of organoids, microphysiological systems, and hydrogels for 3D cell culture. The session will explore their applications in studying disease mechanisms, drug testing, and recent advancements in leveraging these platforms for personalized medicine and therapeutic development.

Moderators:

Silviya Zustiak, Ph.D
Professor and Associate Chair; Co-Director, Institute of Drug and Biotherapeutic Innovation at SLU
Biomedical Engineering
Professor of Pharmacology and Physiology
Saint Louis University

Kyle Lampe
Associate Professor, Chemical EngineeringAssociate Professor, Biomedical Engineering and Neuroscience
The University of Virginia

  • 8:00 AM. 397. Engineered Immune Organoid–on–Chip Platform Reveals Chemokine Receptor Dysregulation Impairs Germinal Center Organization in Lymphoma Patients.Manuel Quiñones-Pérez1, Zhe Zhong1, Jean Koff2, Ankur Singh1 1Georgia Institute of Technology, 2Emory School of Medicine, Emory University
  • 8:15 AM. 398. Engineered Colorectal Cancer Tissue Model in Obesity-linked Insulin-Resistant Microenvironment for Mechanistic Investigation of Disease Progression.Kwaghtaver Desongu1, Ifeoluwa Odeniyi, PhD1, Callie Pope, Student1, Peter Peter Abraham, B.Sc1, Grace Hester, B.Sc1, Michael . Greene, PhD1, Elizabeth Lipke1 1Auburn University
  • 8:30 AM. 399. Tunable Magnetorheological Elastomer Substrates for Studying Mechano-Genetic Interactions in Hypertrophic Cardiomyopathy.Yasaman Kargar Gaz Kooh1, Yuwen Sun1, Bahareh Bahman1, Ganesh Malayath1, Leah Hayem1, Debeni Devi Nongmaithem1, Guy Genin1, Nathaniel Huebsch1 1Washington University in St. Louis
  • 8:45 AM. 400. Comparative Transcriptomic Analysis of a 3D PEG-based Lung Tumor Model to Subcutaneous Xenograft.Suzanne Lightsey1, Heather Kates, PhD1, Kalyanee Shirlekar, PhD1, Jason Brant, PhD1, Blanka Sharma, PhD1 1University of Florida
  • 9:00 AM. 401. Compressive Bioreactor Enables Evaluation of Anti-Inflammatory Drug Responses in Young and Aged Donor-Derived Mesenchymal Stromal Cells.Thai Thanh Hoang1, Katherine Griffin1, Sabrina Mierswa1, J. Kent Leach1 1UC Davis Health
  • 9:15 AM. 402. Engineering Focal Cardiac Fibrosis Models via Digital Light Processing of Hydrogel Molds.Jason Burdick, Ph.D.1, Mackenzie Obenreder, B.S. Biomedical Engineering, Boston University1, Arianna McCarty1 1University of Colorado Boulder
  • 9:30 AM. 396. Talk by Melissa Kemp, Georgia Institute of Technology Speakers Dr. Melissa Kemp