Poster Sessions

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Advances in Ophthalmic Biomaterials

342

Biocompatible and Autoclavable Hydrophilic Coatings for IOL Inserters

W. Lee, K. Miyoshi, D. Nair, I-H. Loh;

AST Products, Inc., Billerica, MA.

343

Enzymatically crosslinked Tetronic-Tyramine Hydrogels for Injectable Intraocular Lens

H. Lee, G. Tae, Y. Kim;

Gwangju Inst. of Sci. and Technology, Gwangju, KOREA, REPUBLIC OF.

344

Characterization of a Monofunctional Siloxane M₁EDS₆TMS using GC/MS and GPC-MALDI-TOF MS to Help Understand Structure/Property Relationships

P. T. Papagelis;

Bausch and Lomb, Rochester, NY.

Biomaterials and Scaffolding for Neural Regeneration

345

A Novel Microchannel-Scaffold Electrode Array for Peripheral Nerve Interfacing

A. Srinivasan, L. Guo, R. V. Bellamkonda;

Georgia Inst. of Technology, Atlanta, GA.

346

Injectable Gelatin-Hydroxyphenylpropionic Hydrogels with Tunable Crosslinking for Supporting and Influencing Adult Neural Progenitor Cells

T. Lim¹, D. Macaya¹, P. Elias¹, W. Toh², M. Kurisawa³, M. Spector⁴;

¹MIT, Cambridge, MA, ²VA Boston Hlth.care System, Boston, MA, ³Inst. of Bioengineering and Nanotechnology, Singapore, SINGAPORE, ⁴Harvard Med. Sch., Boston, MA.

347

In Vivo Analysis Of Poly(N-Isopropylacrylamide)-Poly(Ethylene Glycol) Branched Copolymer As An Injectable Scaffold For Local Delivery Of Neurotrophins And Cellular Transplants

L. Conova¹, J. Vernengo², Y. Jin³, T. Himes³, B. Neuhuber³, I. Fischer³, A. Lowman¹;

¹Drexel Univ., Philadelphia, PA, ²Rowan Univ., Glassboro, NJ, ³Drexel Coll. of Med., Philadelphia, PA.

348

Enhanced Nerve Cell Proliferation and Differentiation Using Polyethylene Glycol Diacrylate-based Hydrogels Grafted with Photo-polymerizable Poly-L-Lysine

L. Cai, S. Wang;

The Univ. of Tennessee Knoxville, Knoxville, TN.

349

Topographical Cues Accelerate Endogenous Regeneration Of Long Peripheral Nerve Gaps

V. Mukhatyar, I. Clements, A. Srinivasan, R. Huber, A. Mehta, S. Rudra, R. Bellamkonda;

Georgia Inst. of Technology, Atlanta, GA.

350

Astrocyte and Glial Restricted Precursor Derived Biomaterials as Coatings for Chronically Implanted CNS Devices

J. L. Skousen, P. A. Tresco;

Univ. of Utah, Salt Lake City, UT.

351

Amphiphilic Polyanhydride Films for Tissue Engineering

L. Petersen, J. Oh, D. Sakaguchi, S. Mallapragada, B. Narasimhan;

Iowa State Univ., Ames, IA.

352

Thermo-Responsive Artificial Extracellular Matrix Protein For Nerve Regeneration

S. Kakinoi, T. Yamaoka;

Natl. Cerebral and Cardiovascular Ctr. Res. Inst., Osaka, JAPAN.

353

Aligned Laminin-Polycaprolactone Blends Promote Regeneration in Tibial Nerve Defect Model

R. A. Neal¹, S. S. Tholpady¹, A. Das¹, R. C. Ogle², E. A. Botchwey¹;

¹Univ. of Virginia, Charlottesville, VA, ²LifeNet Regenerative Med. Inst., Norfolk, VA.

354

Electric Field Enhances Axon Length and Directionality of Dorsal Root Ganglia Embedded in Hydrogel on a Conductive Polypyrrole Substrate

H. T. Nguyen, C. E. Schmidt;

Dept. of BioMed. Engineering, Austin, TX.

355

Bio-Functionalized Electro-Responsive Polymeric Nanowire Templates Facilitating Neural Stem Cell Proliferation and Differentiation

S. Bechara, K. Popat;

Colorado State Univ., Ft Collins, CO.

356

An Injectable Collagen-Genipin Gel for the Treatment of Spinal Cord Injury

D. Macaya¹, K. Shu¹, M. Spector²;

¹Massachusetts Inst. of Technology, Cambridge, MA, ²VA Boston Hlth.care System, Boston, MA.

357

Astrocyte Reactivity to Neural Implant with Porous Silicon Backbone Support

E. S. Ereifej, J. Yang, M-C. Cheng, P. J. VandeVord;

Wayne State Univ., Detroit, MI.

358

New Flexible Elastomer Nerve Conduit for Peripheral Nerve Injury Repair

W. Choy¹, R. Tran², K. Yeung¹, J. Yang², W. Ip¹;

¹The Univ. of Hong Kong, Hong Kong SAR, HONG KONG, ²The Univ. of Texas at Arlington, Arlington, TX.

359

An Electrospun Scaffold Composed of Basal Lamina Proteins for Use in Neural Tissue Repair

R. L. Miller, P. J. VandeVord;

Wayne State Univ., Detroit, MI.

360

Neurite Growth in PEG Gels: Effect of Mechanical Stiffness and Laminin Concentration

L. Marquardt, R. K. Willits;

Saint Louis Univ., St. Louis, MO.

Animal Models for Biomaterial and Medical Device Testing

361

Biomaterial Screening for Lymphatic Regeneration

E. M. Brown, U. Mendez, M. Roberts;

Michigan Technological Univ., Houghton, MI.

362

Evaluation of Bone Substitutes and Gene Expression Pattern in a Tibia Defect Model in the Rat

C. Ganz¹, W. Xu¹, S. Lenz², D. Koczan³, T. Gerber¹;

¹Insitute of Physics, Rostock, GERMANY, ²Dept. of Oral, Maxillofacial and Plastic Surgery, Rostock, GERMANY, ³Inst. of Immunology, Rostock, GERMANY.

363

Small Animal Model to Measure Collagen Deposition Using a Knit Construct: A Preliminary Study

S. J. Peniston¹, J. T. Corbett¹, K. J. L. Burg², S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

364

Toxicity Study of Recombinant Human Platelet-Derived Growth Factor-BB Hydrated Bovine Type I Collagen in Decorated Femur Model in Rabbits---a Safety Study Model for Rotator Cuff Repair

Y. Liu, J. Ratliff, V. Shah, Y. Zhou, H. Kestler, S. E. Lynch, D. Aguiar;

BioMimetic Therapeutics, Inc, Franklin, TN.

365

PEEK Versus Trabecular Metal Implants for Cervical Spinal Fusion in a Goat Model

S. K. Sinclair¹, G. Konz², J. Dawson², R. D. Bloebaum¹;

¹Univ. of Utah, Salt Lake City, UT, ²Zimmer Spine, Inc., Minneapolis, MN.

366

Platelet Activation in Juvenile Ovines Implanted With the Levitronix Pedivas Ventricular Assist Device

V. Shankarraman¹, C. A. Johnson, Jr.¹, T. M. Maul¹, J. Marks², K. Dasse², W. R. Wagner¹;

¹Univ. of Pittsburgh, Pittsburgh, PA, ²Levitronix, Waltham, MA.

The Art of Falling Apart: Exploiting Biomaterial Degradation

367

In vitro Degradation Study of Poly(L-lactide)-Based Fibers using Dynamic Mechanical Analysis

N. D. Belcheva, R. Shah, O. Fabien, D. Beers, A. Hadba;

Covidien, North Haven, CT.

368

Development of an Absorbable Synthetic Bone Wax

K. D. Gray, M. S. Taylor, J. T. Corbett, W. S. W. Shalaby, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

369

Hydrolytic Degradation of Electrospun Polycaprolactone and Polyglycolide Copolymer Blends

A. S. Chung¹, H. Hwang¹, P. Zuk¹, D. R. McAllister², B. M. Wu¹;

¹Univ. of California at Los Angeles, Los Angeles, CA, ²Dept. of Veteran Affairs, Los Angeles, CA.

370

Modulation of Degradation Profile in Biphasic Polymer Systems

M. S. Taylor, B. P. Baum, D. E. Linden, S. J. Peniston, K. A. Carpenter, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

371

Platelet-Rich Plasma: An Autologous Agent for MSC Migration, Proliferation, Delivery, and Cryopreservation for Regenerative Medicine

M. B. Murphy¹, R. M. Buchanan¹, D. Blashki², I. K. Yazdi¹, P. J. Simmons², E. Tasciotti¹;

¹The Methodist Hosp. Res. Inst., Houston, TX, ²The Univ. of Texas Hlth.Sci. Ctr. at Houston, Houston, TX.

372

Effects Of Crosslinking Density On Viability And Maintenance Of Human Embryonic Stem Cell-Derived Cardiomyocytes In Elastin-Like Hydrogels

C. Chung, M. Marchand, B. L. Pruitt, S. C. Heilshorn;

Stanford Univ., Stanford, CA.

373

Stiffness Modulates Chondrogenic and Osteogenic Differentiation of Human Mesenchymal Stem Cells

R. Olivares-Navarrete, K. Smith, S. L. Hyzy, D. Haithcock, K. Gall, B. D. Boyan, Z. Schwartz;

Georgia Inst. of Technology, Atlanta, GA.

374

Bioengineering of the Embryonic Cardiovascular Progenitor Cell Niche Using Electrospun Nanofibrous Scaffolds

J. M. Gluck, R. J. Shemin, S. Heydarkhan-Hagvall;

Univ. of California, Los Angeles, Los Angeles, CA.

375

Directing Neuronal Differentiation Via Neurochemical Release From Carbon Nanotube-doped Conducting Polymers

C. L. Weaver, X. T. Cui;

Univ. of Pittsburgh, Pittsburgh, PA.

376

A Collagen-Based Matrix that Enhances Cardiac and Skeletal Myogenesis in Mouse Embryonic Stem Cells

D. Ebadi;

Univ. of Ottawa, Ottawa, ON, CANADA.

377

Nanofiber Scaffolds Induce Morphological Changes in hBMSCs Critical for Osteogenic Differentiation

C. K. Tison, G. Kumar, C. G. Simon, Jr.;

Natl. Inst. of Standards and Technology, Gaithersburg, MD.

378

Selective Activation of Sphingosine 1-Phosphate Receptors for Progenitor Cell Recruitment and Fracture Healing

M. R. Tinius, E. A. Botchwey;

Univ. of Virginia, Charlottesville, VA.

379

Biomimetic Thymic Niche for Generating Functional, Antigen-Specific T Cells from Stem Cells: Quantitative Control of Notch and T Cell Receptor Signaling Through Biomaterials

M. Kim¹, J. Lin², M. Mendoza¹, K. Roy¹;

¹Univ. of Texas at Austin, Austin, TX, ²XBiotech, Austin, TX.

380

Fatty Acid-Loaded Chitosan-Gelatin Beads for Adipose Tissue Engineering

C. Gomillion, K. Burg;

Clemson Univ., Clemson, SC.

381

Heparin Hydrogels Promote Mineralization of Encapsulated Mesenchymal Stem Cells in Coculture with Osteoblasts

S. P. Seto, R. C. Adams, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.

382

Hydrolytically Degradable Poly(Ethylene Glycol)-Laminin Hydrogel Scaffolds for Neural Progenitor Cell Delivery

A. S. Ribeiro, D. Hughes, H. Gaifem, S. P. Zustiak, J. B. Leach;

Univ. of Maryland Baltimore County, Baltimore, MD.

383

Hydrogel Nanofiber Stiffness Influences Mesenchymal Stem Cell Spreading and Vascular Differentiation in 3D Matrix

K. A. Wingate, D. Scott, W. Bonani, W. Tan, S. Bryant;

Univ. of Colorado, Boulder, Boulder, CO.

384

Self-assembling hMSC Sheets Incorporating Degradable Polymer Microspheres for Cartilage Tissue Engineering

L. D. Solorio, C. D. Dhami, A. Whitney, E. Alsberg;

Case Western Reserve Univ., Cleveland, OH.

385

Investigation of Pore Size Effect on Adipose Stem Cell Differentiations Using a Pore Size Gradient Scaffold

T. Kim¹, S. Oh¹, E. Kwon², J. Lee², J. Lee¹;

¹Hannam Univ., Daejeon, KOREA, REPUBLIC OF, ²Catholic Univ., Seoul St. Mary's Hosp., Seoul, KOREA, REPUBLIC OF.

386

Cardiac Commitment on Compliant Polymeric Substrata

C. LeBlon, S. Jedlicka;

Lehigh Univ., Bethlehem, PA.

387

Development of Bioactive Poly(ethylene glycol) (PEG) Hydrogels to Promote Expansion of Hematopoietic Stem Cells and Maintain their Potency

M. L. Rowland¹, O. A. Banda¹, S. Coskun², K. K. Hirschi², J. L. West¹;

¹Rice Univ., Houston, TX, ²Baylor Coll. of Med., Houston, TX.

388

Preparation of Functional Silicate-substituted Hydroxyapatite and Its in vitro Investigation of Mechanism for Promoting Bone Formation

Z. Qiu, C. Chen, J. Liu, J. Wang, S. Zhang;

Huazhong Univ. of Sci. and Technology, Wuhan, CHINA.

389

Independently Tunable Matrix Elasticity and Cell Shape for Directed Mesenchymal Stem Cell Differentiation

B. J. Gill, J. L. West;

Rice Univ., Houston, TX.

390

Material-Based Cues that Influence Mesenchymal Stem Cell Differentiation to Cartilage

J. N. Renner, J. C. Liu;

Purdue Univ., West Lafayette, IN.

391

Graphite Oxide Nanoparticles Larger than 20nm in Diameter are Biocompatible with Mouse Embryonic Stem Cells

I-N. E. Wang, J. T. Robinson, G. Do, G. Hong, D. R. Gould, H. Dai, P. Yang;

Stanford Univ., Stanford, CA.

392

Behavior of Dental Pulp Stem Cells on Polyvinyl Alcohol/Halloysite Nanotube Electrospun Nanofibrous Scaffolds

W. Zhou¹, A. Elsayed¹, A. Rabie¹, R. Liao², B. Guo²;

¹Faculty of Dentistry, The Unversity of Hong Kong, Hong Kong, HONG KONG, ²South China Univ. of Technology, Guangzhou, CHINA.

393

Creation Of A Collagen Scaffold Integrating Mesenchymal Stem Cells And Microencapsulated Peptides For Use In Wound Healing.

K. B. Moore, W. Zhang, J. Potts;

Univ. of South Carolina, Columbia, SC.

394

Osteogenesis, Adipogenesis, and Myogenesis of Rat Mesenchymal Stem Cells on The Nanogrooved Surfaces

P-Y. Wang;

Natl. Taiwan Univ., Taipei, TAIWAN.

395

Biphasic Calcium Phosphate Bioceramics Modulate Stem Cells and Pre-Osteoblasts` Phenotype

S. E. Lobo, R. Glickman, D. N. Levy, L. Terracio, R. Z. LeGeros;

New York Univ., New York, NY.

396

Single Cell PCR Study of Rat Mesenchymal Stem Cells Cocultured With Cardiomyocytes

Q. Liu¹, Z. Ma², L. Wei³, Y. Wang¹, B. Xu⁴, X. Guo⁴, B. Gao²;

¹BioMed. Res. & Develop Ctr., Guangzhou, CHINA, ²Bioengineering Dept., Clemson, SC, ³Ctr. for BioMed. Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking Univ., Beijing, CHINA, ⁴Grandhope Biotech Co., Ltd., Guangzhou, CHINA.

397

Biomaterial Systems to Assess the Influence of Cell-Matrix Interactions on Hematopoietic Stem Cells

J. Choi, B. Harley;

Univ. of Illinois at Urbana-Champaign, Urbana, IL.

398

Placenta Stem Cells Differentiation onto PU foams

S. Bertoldi¹, S. Fare'¹, D. Rossi², H. J. Haugen³, O. Parolini², M. Tanzi¹;

¹Politecnico di Milano, Milano, ITALY, ²Centro di Ricerca E. Menni Fondazione Poliambulanza, Brescia, ITALY, ³Univ. of Oslo, Oslo, NORWAY.

399

Control of Mesenchymal Stem Cell Chondrogenesis in Micromass and on Collagen Scaffolds by Autocrine Transglutaminases

S. Shanmugasundaram, M. Nurminskaya;

Univ. of Maryland-Sch. of Med., Baltimore, MD.

400

The Effects of rhPDGF-BB Alone and Combination with rhBMP-2 to Promote the Osteogenic Differentiation of Human Mesenchymal Stem Cells

J. Kim;

Carnegie Mellon Univ., Pittsburgh, PA.

401

Surface Phosphorylation for Polyelectrolyte Complex of Chitosan and Its Sulfonated Derivative: Surface Analysis, Blood Compatibility and Adipose Derived Stem Cell Contact Properties

H-Y. Yeh, J-C. Lin;

Natl. Cheng Kung Univ., Tainan, TAIWAN.

402

Gradient Cell Density Formation and Adipogenic Differentiation of Mesenchymal Stem Cells on a Micropattened Surface

N. Kawazoe, H. Lu, T. Tateishi, G. Chen;

Natl. Inst. for Materials Sci., Tsukuba, JAPAN.

403

Protein and Polyphenols Contaminants of Sodium Alginates and Their Effect on Viability of Mesenchymal Stem Cells Derived from Human Umbilical Cord

U. Kandalam, A. I. Cabel, H. Omidian, S. K. McCarthy, E. J. Stelnicki;

Nova Southeastern Univ., Fort lauderdale, FL.

404

Human Mesenchymal Stem Cell Proliferation as a Function of Scaffold Position in a Tubular Perfusion System

E. M. Geibel, A. B. Yeatts, J. P. Fisher;

Univ. of Maryland, College Park, MD.

405

Poly(Ethylene Glycol) Microsphere-Encapsulated Pluripotent Stem Cells: Control Of Microsphere Size For Cardiac Differentiation

S. S. Chang, B. A. Williams, E. A. Lipke;

Auburn Univ., Auburn, AL.

Cellular Responses to Biophysical Cues

406

Flow Perfusion Bioreactor for Bone and Cartilage Tissue Engineering

V. V. Meretoja, R. L. Dahlin, K. F. Kasper, A. G. Mikos;

Rice Univ., Houston, TX.

407

Effect of Focal Adhesion Spatial Distribution on Cell-Substrate Adhesion Strength

K. Elineni, N. D. Gallant;

Univ. of South Florida, Tampa, FL.

408

Cardiomyocyte Response to Ultra Stiff Hydrogel Substrates

S. L. Hume, S. J. Bryant;

Univ. of Colorado at Boulder, Boulder, CO.

409

Endothelial Cell Attachment and Shear Response on Biomimetic Polymer Coated Vascular Grafts

L. Dudash¹, F. Kligman², S. Sarett¹, K. Kottke-Marchant², R. Marchant¹;

¹Case Western Reserve Univ., Cleveland, OH, ²Cleveland Clinic, Cleveland, OH.

410

Identification of Endothelial Cells Using Receptor Expression Changes in Microfluidic Channels

D. Vickers, S. Murthy;

Northeastern Univ., Boston, MA.

411

Regulation of Smooth Muscle Cell Behavior on Novel Biodegradable Elastomeric Substrates with Controllable Stiffness

X. Liu, L. Cai, S. Wang;

The Univ. of Tennessee Knoxville, Knoxville, TN.

412

Development of a Collagen-GAG Scaffold Microarray for High-Throughput Analysis of Cell Fate Decisions

E. A. Gonnerman, L. M. McGregor, B. A. Harley;

Univ. of Illinois at Urbana-Champaign, Urbana, IL.

413

Understanding Osteoblast Responses on Stiff Nanotopographies Through Experiments and Computational Simulations

L. Yang, V. Chinthapenta, Q. Li, D. Stout, A. Liang, B. W. Sheldon, T. J. Webster;

Brown Univ., Providence, RI.

414

Differential Response of Staphylococci and Osteoblasts to Varying Titanium Surface Roughness

Y. Wu¹, J. P. Zitelli², K. S. TenHuisen², X. Yu¹, M. R. Libera¹;

¹Stevens Inst. of Technology, Hoboken, NJ, ²Stryker Orthopaedics, Mahwah, NJ.

415

Role of Integrin Subunits in Osteoblast Maturation on Microstructured Surfaces with Different Chemistries

R. Olivares-Navarrete¹, S. L. Hyzy¹, A. Almaguer-Flores², G. R. Dunn¹, C. Appert³, S. E. Rodil², B. D. Boyan¹, Z. Schwartz¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Univ. Natl. Autonoma de Mexico, Mexico City, MEXICO, ³Inst. Straumann, Basel, SWITZERLAND.

416

Organization and Differentiation of Retinal Progenitor Cells on Microfabricated Poly(e-caprolactone) Thin Films

C. Ko¹, J. Yao², S. Tao³, M. Young²;

¹Massachusetts Inst. of Technology, Cambridge, MA, ²Schepens Eye Res. Inst., Cambridge, MA, ³Draper Lab., Cambridge, MA.

417

Matrix Modulus Influences the Development of Breast Acini and Ducts in 3D Cultures

C-C. Yang¹, M. Swamydas², D. Dean¹, D. Dréau¹, K. Burg¹;

¹Inst. for biological interfaces of engineering, Clemson, SC, ²Cellular and Molecular Biology Div., Dept. of Biology, Univ. of North Carolina, Charlotte, NC.

418

Imparting Physical Load to Synthetic Extracellular Matrices Using Ultrasound

S. Frazee¹, V. Palumbo¹, J. Veronick¹, B. Huey¹, Y. Khan²;

¹Univ. of Connecticut, Storrs, CT, ²Univ. of Connecticut Hlth.Ctr., Farmington, CT.

419

Biomimetic Platform to Study Effects of Surface Topography and Flow-induced Shear Stress on Renal Epithelial Cells

E. M. Frohlich, J. L. Charest;

Charles Stark Draper Lab., Cambridge, MA.

420

Cell Regulation by Ion-Beam Induced Nanostructures

Z. Yang, A. M. Kacic, N. Samuelson, C. L. Cooper, J. P. Allain, L. M. Reece;

Purdue Univ., West Lafayette, IN.

421

Influence of Topography of Endovascular Stent Material on Smooth Muscle Cell Response

B. H. Winn;

Clemson Univ., Clemson, SC.

422

In Vitro Evaluation of a Novel Biosynthetic Hydrogel

M. L. Godek, K. Lavigne, N. Mast, W. Skalla, A. Throm, J. Mayotte, R. Bushnell, S. Bennett;

Covidien Surgical Devices, North Haven, CT.

423

Monitoring Oxidative Stress in Osteoblast-Like Cells Using Quartz Cristal Microbalance with Dissipation

C. Tkaczyk, M. Tabrizian;

McGill Univ., Montréal, QC, CANADA.

424

A Novel Univarient Material for the Study of Cellular Response to Material Rigidity

E. L. Hedberg-Dirk, A. T. Leonard, K. N. Cicotte, J. R. Funston;

Univ. of New Mexico, Albuquerque, NM.

425

Loading and Release Kinetics, and Fibroblast Attachment to Fibronectin Functionalised HA In Vitro.

C. J. Pendegrass, M. El-Husseiny, G. Blunn;

Univ. Coll. London, Stanmore, Middlesex, UNITED KINGDOM.

Molecular Mechanisms Mediating Protein-Surface and Cell-Surface Interactions

426

Targeting the SIRPα1 Signaling Pathway to Reduce the Inflammatory Response to Polymeric Surfaces

M. J. Finley, R. J. Levy, S. J. Stachelek;

Children's Hosp. of Philadelphia Res. Inst., Philadelphia, PA.

427

Development and Validation of an Interfacial Force Field for the Accurate Simulation of Protein-Surface Interactions

R. A. Latour¹, N. A. Vellore¹, J. A. Yancey¹, T. Kucukkal¹, S. J. Stuart¹, P. K. Biswas²;

¹Clemson Univ., Clemson, SC, ²Tougaloo Coll., Tougaloo, MS.

428

Active Endothelial Targeting Antioxidant Nanoparticles for the Suppression of Vascular Oxidative Stress

D. B. Cochran, P. Wattamwar, K. Anderson, R. Eitel, T. Dziubla;

Univ. of Kentucky, Lexington, KY.

429

Time-Lapse Study of Cellular Adhesion on a Cathodically Polarized Cocrmo Alloy

M. Haeri, T. Wollert, J. L. Gilbert;

Syracuse Univ., Syracuse, NY.

430

Poly(ethylene glycol)-tethered Biodegradable Elastomers for Regulating Surface Characteristics and Nerve Cell Behavior

L. Cai, S. Wang;

The Univ. of Tennessee Knoxville, Knoxville, TN.

431

Osteoblast Response to Protein Adsorption to 3D Polymer Scaffolds Through Pre-Ageing in Cell Medium

K. Chatterjee, S. Hung, C. G. Simon, Jr.;

Natl. Inst. of Standards and Technology, Gaithersburg, MD.

432

Comparative Assessment of Iridium Oxide and Platinum Wires Using an In Vitro Glial Scar Assay

E. S. Ereifej, S. Khan, G. Newaz, P. VandeVord;

Wayne State Univ., Detroit, MI.

Novel Approaches to Cellular Therapies

433

Fibrin Based Hydrogels to Promote Healing and Limit Infection in Wound Therapy

S. Seetharaman¹, R. S. Stowers², S. Natesan¹, D. O. Zamora¹, R. J. Christy¹, L. J. Suggs²;

¹US Army Inst. of Surgical Res., Fort Sam Houston, TX, ²Univ. of Texas at Austin, Austin, TX.

434

Poly(vinyl alcohol)- Heparin Biosynthetic Hydrogel Microspheres for Cell Encapsulation

C. J. Young, L. A. Poole-Warren, P. J. Martens;

Graduate Sch. of BioMed. Engineering, The Univ. of New South Wales, Sydney, AUSTRALIA.

435

Uniform Beads with Controllable Pore Sizes for Biomedical Applications

Y. Zhang¹, S-W. Choi¹, Y-C. Yeh¹, H-W. Sung², Y. Xia¹;

¹Washington Univ. in St. Louis, St. Louis, MO, ²Natl. Tsing Hua Univ., Hsinchu, TAIWAN.

436

Do Differentiated Osteoblasts and Allogeneic Mesenchymal Stromal Cells Augment Bone Formation?

M. J. Coathup, S. Konan, K. Mirza, P. Kalia, G. W. Blunn;

Univ. Coll. London, Stanmore, Middlesex, UNITED KINGDOM.

437

Injectable Alginate Microcapsule/Polyurethane Composite Scaffolds for Cell Therapy

B. Lee, S. A. Guelcher, B. Li;

Vanderbilt Univ., Nashville, TN.

Pluripotent Stem Cells in Engineered Microenvironments

438

Fabrication of a Human Cardiac Tissue Equivalent In Vitro On Synthetic 3D Fiber Scaffolds

R. Gupta, H. Jeon, C. P. Grigoropoulos, K. E. Healy;

Univ. of California, Berkeley, CA.

439

Controlled Electrophysiological Maturation of Stem Cell-Derived Cardiomyocytes

A. J. Hodge, E. A. Lipke;

Auburn Univ., Auburn, AL.

Macrophage-centered Host Response to Biomaterials and Wound Healing

440

Proteomic Analysis of Protein Adsorption onto a Degradable-Polar/Hydrophobic/Ionic Polyurethane

K. Battiston¹, R. Labow², J. Santerre¹;

¹Univ. of Toronto, Toronto, ON, CANADA, ²Univ. of Ottawa Heart Insitute, Ottawa, ON, CANADA.

441

Effect of Transforming Growth Factor -Beta1 (TGF-ß1) On Human Vocal Fold Fibroblasts In 3-Dimensional (3-D) Hyaluronan Hydrogel Environment

X. Chen, S. L. Thibeault;

Univ. of Wisconsin-Madison, Madison, WI.

442

Incorporation of RGD Attenuates the Foreign Body Reaction to PEG Hydrogels

M. D. Swartzlander;

Univ. of Colorado, Boulder, CO.

443

Modulation of Human Monocyte Phenotypic Polarization by Biomaterials and Xenoproteins

H. Waldeck¹, D. Schmidt¹, X. Wang², E. J. Joyce¹, W. Kao¹;

¹Univ. of Wisconsin - Madison, Madison, WI, ²Univ. of Minnesota, Minneapolis, MN.

444

M1 and M2 Macrophage Polarization in Pseudomembranes from Total Joint Replacement

A. J. Rao, T. Ma, S. Goodman;

Stanford Univ. Sch. of Med., Stanford, CA.

445

Understanding Macrophage Activation in Response to LPS-stimulation When Cultured on PEG-RGD Hydrogels

R. Lawall, A. Blakney, M. D. Swartzlander, S. J. Bryant;

Univ. of Colorado, Boulder, CO.

Biomaterials-based Therapies Exploiting Immunological Processes

446

Adjuvant Optimization Using Cellular Arrays for Vaccine Development

A. P. Acharya, N. Dolgova, B. Keselowsky;

Univ. of Florida, Gainesville, FL.

447

Development of Interbilayer-Crosslinked Multilamellar Vesicles as a Potent Vaccine Platform

J. Moon, H. Suh, A. Bershteyn, M. Stephan, S. Luo, D. Irvine;

MIT, Cambridge, MA.

448

Design of “Pathogen-Mimicking” Polyanhydride Adjuvants

L. Petersen, B. Ulery, S. Broderick, Y. Phanse, C. Sun Kong, A. Ramer-Tait, B. Bellaire, M. Wannemuehler, K. Rajan, B. Narasimhan;

Iowa State Univ., Ames, IA.

449

Protein Stability upon Encapsulation and Release From Polyanhydride Nanoparticles

B. R. Carrillo-Conde, S. J. Seiler, M. Dey, A. Ramer-Tait, M. J. Wannemuehler, B. Narasimhan;

Iowa State Univ., Ames, IA.

Animating Materials

450

Thrombogenicity Ranking of Metal and Diamond-like Carbon Coated Polyurethane Surfaces under Dynamic Test Conditions

J. M. Lackner¹, M. Kahn¹, W. Waldhauser¹, P. Hartmann¹, F. Bruckert², M. Weidenhaupt², R. Major³, M. Sanak⁴;

¹Joanneum Research, Graz, AUSTRIA, ²Grenoble Inst. of Technology, Grenoble, FRANCE, ³Polish Academy of Sci. - Inst. of Metallurgy and Material Sci., Krakow, POLAND, ⁴Jagiellonian Univ. Med. Coll., Dept. of Med., Krakow, POLAND.

451

Strain Responsive Surface Patterns to Dynamically Control Cell and Nuclear Alignment

M. Guvendiren, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

452

Synthetic Cells with Ordered Protein Patches

K. Kamalasanan;

Univ. of Pittsburgh, Pittsburgh, PA.

453

Synthesis and Characterization of a Novel Nanofibrous Bioactive Prosthetic Sewing Cuff

S. G. Pathan¹, M. J. Bide², T. E. Phaneuf¹, K. J. Kenney¹, M. A. Contreras³, M. D. Phaneuf¹;

¹BioSurfaces Inc., Ashland, MA, ²Univ. of Rhode Island, Kingston, RI, ³Beth Israel Deaconess Med. Ctr., Boston, MA.

454

Coaxial Electrospun Nanoactuating Poly(ε-caprolactone), Multi-walled Carbon Nanotubes, and Polyacrylic acid/Polyvinyl Alcohol Hydrogel Scaffolds

K. D. McKeon-Fischer, J. W. Freeman;

Virginia Polytechnic Inst. and State Univ., Blacksburg, VA.

455

Targeted Delivery of Silencing RNA Utilizing Nanofibrous Polyester Materials

M. D. Phaneuf¹, L. M. Fitzgerald¹, S. M. Ali¹, S. G. Pathan¹, T. E. Phaneuf¹, K. J. Kenney¹, T. M. Phaneuf¹, M. J. Bide²;

¹BioSurfaces, Inc., Ashland, MA, ²Univ. of Rhode Island, Kingston, RI.

456

Microencapsulation of Octylcyanoacrylate to Achieve Self-healing in PMMA Bone Cement

A. Brochu, V. Gandham, W. Reichert;

Duke Univ., Durham, NC.

457

Ph-Responsitive Poly(Beta-Amino Ester) Polymers With Tunable Transition Point

Z. Tang;

Changchun Inst. of Applied Chemistry, Changchun, CHINA.

458

Effect of Daily Living Activities on the Stability on Pertrochanteric Fracture Fixation Devices

A. Grujicic, M. Grujicic, X. Xie, G. Arakere, B. Pandurangan, K. Jeray;

Clemson Univ., Clemson, SC.

Biomimetic Materials for Tissue Engineering

459

Engineering a Cell-Adhesive and Biodegradable Hydrogel for Smooth Muscle Cell Attachment and Growth

L. Lin¹, J. Zhu¹, K. Kottke-Marchant², R. Marchant¹;

¹Case Western Reserve Univ., Cleveland, OH, ²Pathology and Lab. Med. Inst., Cleveland Clinic, Cleveland, OH.

460

Dense Collagen/Chitosan Hybrid Gels as Scaffolds for Cartilage Tissue Engineering

F. Chicatun, C. E. Pedraza, N. Muja, C. E. Ghezzi, M. D. McKee, S. N. Nazhat;

McGill Univ., Montreal, QC, CANADA.

461

Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells

G. Kumar¹, C. G. Simon, Jr.¹, M. F. Young²;

¹Natl. Inst. for standards and technology, Gaithersburg, MD, ²Natl. Inst. of Health/NIDCR, Bethesda, MD.

462

Modified Hyaluronic Acid Based Hydrogels to Promote Spreading and Proliferation of Endothelial Progenitor Cells

G. Camci-Unal, A. Khademhosseini;

Harvard-MIT Div. of Hlth.Sci. and Technology; Ctr. for BioMed. Engineering, Dept. of Med., Brigham and Women’s Hosp., Harvard Med. Sch., Cambridge, MA.

463

Incorporation of Particulate Hydroxyapatite into Collagen-based, Cell-laden Microbeads

R. R. Rao, L. Wang, J. P. Stegemann;

Univ. of Michigan, Ann Arbor, MI.

464

Biomimetic Mineralization of Dense Collagen Substrates Derived from Demineralized Manatee Bone

T. Thula-Mata;

Univ. of Florida, Gainesville, FL.

465

Biosynthetic PEG-MAL Hydrogel Stimulates Angiogenic Sprouting in Mouse Aortic Rings

R. Rath, E. A. Phelps, A. J. Garcia;

Georgia Inst. of Technology, Atlanta, GA.

466

Silica-Collagen-Calcium Phosphate Composite Materials for Bone Replacement. In Vitro-Manipulation of the Ratio of Bone-Building to Bone-Resorbing Cells in a Co-Culture Model

T. Hanke;

Technische Univ. Dresden, Dresden, GERMANY.

467

Mechanical Property-Tunable and Cytocompatible Phospholipid Polymer Hydrogels for Cell Encapsulation

H. Oda, T. Konno, K. Ishihara;

The Univ. of Tokyo, Tokyo, JAPAN.

468

Adhesive Peptides Modified with Long Spacers Encourage Human Corneal Epithelial Cell Attachment and Spreading

M. J. Wilson¹, S. J. Liliensiek¹, C. J. Murphy², W. L. Murphy¹, P. F. Nealey¹;

¹Univ. of Wisconsin, Madison, WI, ²Univ. of California, Davis, CA.

469

Bisphosphonate Modified Hydroxyethylchitosan as a Bone Scaffold for Bone Regeneration

S. R. Barnes, N. Pothayee, N. Pothayee, A. Whittington, J. S. Riffle;

Virginia Polytechnic Inst. and State Univ., Blacksburg, VA.

470

Fabrication and Mechanical Evaluation of Anatomically Inspired Advanced Hydrogel Structures

C. Durst, M. P. Cuchiara, J. L. West, K. J. Grande-Allen;

Rice Univ., Houston, TX.

471

Biocompatibility of Segmented Poly(urethane-urea) Elastomers Based on Polycaprolactone

A. Paredes-Puerto¹, D. Dashti², Y. Yeghiazarians³, E. Guzmán-Marín⁴, K. E. Healy⁵, F. Hernández-Sánchez¹;

¹Centro de Investigación Científica de Yucatán AC, Mérida, MEXICO, ²Dept. of Bioengineering, Univ. of California at Berkeley, Berkeley, CA, ³UCSF Med. Ctr., Long Hosp., San Francisco, CA, ⁴Laboratorio de Biología Celular, Centro de Investigaciones Regionales “Dr. Hideyo Noguchi”, Univ. Autónoma de Yucatán, Mérida, MEXICO, ⁵Dept. of Bioengineering & Dept. of Material Sci. and Engineering, Univ. of California at Berkeley, Berkeley, CA.

472

In Vitro Biomineralization of Carbon Nanotube/Hidroxyapatite Composites Obtained By Electrodeposition Process

A. O. Lobo, Jr.¹, A. E. C. Granato, Jr.², S. C. Ramos, Jr.³, C. Pacheco-Soares, Sr.², M. A. F. Corat, Sr.⁴, E. J. Corat, Sr.³;

¹ITA, Sao Jose dos Campos, BRAZIL, ²UNIVAP, Sao Jose dos Campos, BRAZIL, ³INPE, Sao Jose dos Campos, BRAZIL, ⁴CEMIB/UNICAMP, Campinas, BRAZIL.

473

In Vitro Osseogenesis at the Bone-Implant Interface Under Cyclic Tensile and Compressive Strains

A. P. Noblett, J. D. Bumgardner;

Univ. of Memphis, Memphis, TN.

474

Porous Titanium Scaffolds with Controlled Pore Size by Combination of Freeze Casting and Space Holder Methods

S. Kim¹, H. Jung¹, S. Yook¹, H. Kim¹, Y. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

475

Porous Poly(Ɛ-caprolactone)/Hydroxyapatite Scaffold with Highly Aligned Pore Structure using Unidirectional Freeze Drying

W-Y. Choi¹, J-H. Lee¹, Y. Jin¹, H-E. Kim¹, Y-H. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

476

Porous Calcium Phosphate (CaP) Scaffolds with a Core/Shell Structure Using Indirect Solid Freeform Fabrication (ISFF)

Y. H. Jin¹, W. Y. Choi¹, H. E. Kim¹, Y. H. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

477

Recombinant Silk-Elastinlike Protein Polymer as an Ocular Drug Delivery System

W. Teng¹, J. Cappello², X. Wu¹;

¹Univ. of Arizona, Tucson, AZ, ²Protein Polymer Technologies, Inc., San Diego, CA.

478

Apatite Coated MWCNT Provide a Biomimetic Surface for the Culture of Osteogenic Cells

O. Emohare¹, I. Kinloch², N. Rushton¹;

¹Univ. of Cambridge, Cambridge, UNITED KINGDOM, ²Sch. of Materials, Univ. of Manchester, Manchester, UNITED KINGDOM.

479

Porous Titanium Scaffolds by Dynamic Freeze Casting for Bone Tissue Engineering

H-D. Jung, H-E. Kim;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

480

Porous Polyurethane Composites as Scaffolds for Bone Regeneration: Comparison between Micro- and Nano- Sized Hydroxyapatite Fillers

S. Fare', S. Bertoldi, M. Tanzi;

Politecnico di Milano, Milan, ITALY.

481

Elastic Matrix Regeneration in Collagen-Rich Tissues Require Elastogenic Induction of Cells

L. Venkataraman¹, A. Ramamurthi²;

¹Clemson Univ./ Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic, Cleveland, OH.

482

Combined Effects of Physical and Biochemical Stimuli on HUVECs In Vitro: A Multilayer Film Study

E. Cho, D. T. Haynie;

Univ. of South Florida, Tampa, FL.

483

Production of Porous Poly(ε-caprolactone)/Silica Hybrid Membranes with Patterned Surface Pores

K-H. Shin¹, Y-W. Moon¹, Y-H. Koh¹, W-Y. Choi², H-E. Kim²;

¹Korea Univ., Seoul, KOREA, REPUBLIC OF, ²Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

485

Quantification of Topologic characters and Prime Proteins of Esophageal Basement Membrane for Scaffold Design in Tissue Engineering

Y. Zhu¹, J. Fang²;

¹Ningbo Univ., Ningbo, CHINA, ²Ningbo Univ. of Technology, Ningbo, CHINA.

Advances in Tissue Engineering Scaffolding: Fabrication and Modification

486

Tunable Electrospun Hyaluronic Acid Scaffolds to Mimic the Microenvironment and Structure of Articular Cartilage

I. L. Kim, H. G. Sundararaghavan, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

487

Bioactive Glass Scaffolds for Repair and Regeneration of Load-bearing Bone Defects

Q. Fu¹, A. P. Tomsia¹, E. Saiz²;

¹Lawrence Berkeley Natl. Lab., Berkeley, CA, ²Imperial Coll. London, London, UNITED KINGDOM.

488

Oxidation for Enhanced Degradation of Hydrogels Formed From Photocrosslinkable Alginate

O. Jeon, S. M. Ahmed, D. Alt, C. Powell, E. Alsberg;

Case Western Reserve Univ., Cleveland, OH.

489

Electrospun Gelatin Scaffolds with Biological and Architectural Cues Direct Cell Proliferation and Alignment

R. B. Montero, D. T. Nguyen, K. L. Hernandez, F. M. Andreopoulos;

Univ. of Miami, Miami, FL.

490

NIST Reference Material Scaffolds Characterized for Cell Response

C. G. Simon, Jr., J. M. Coles;

NIST, Gaithersburg, MD.

491

Biofabrication of a Lamellar Elastic Scaffold for Intervertebral Disc Regeneration

B. R. Whatley¹, Y. Qiu¹, B. Damon², J. Kuo¹, X. Wen¹;

¹Clemson Univ., Charleston, SC, ²Med. Univ. of South Carolina, Charleston, SC.

492

Fabrication of Electrospun 3D Scaffolds That Mimic Cortical Bone

T. Andric, J. W. Freeman;

Virginia Polytechnic Inst. and State Univ., Blacksburg, VA.

493

Preparation of Funnel-Like Collagen Porous Scaffolds and Application for Cartilage Tissue Engineering

G. Chen, H. Lu, Y-G. Ko, N. Kawazoe;

Natl. Inst. for Materials Sci., Tsukuba, JAPAN.

494

Immobilization of bFGF on Heparinized Thermoresponsive Cell Culture Surface for Enhancing Cell Growth

Y. Arisaka, J. Kobayashi, M. Yamato, Y. Akiyama, T. Okano;

Inst. of Advanced BioMed. Engineering and Sci., Tokyo Women’s Med. Univ., Tokyo, JAPAN.

495

Two-Phase Scaffold for Load Bearing Soft Tissue Repair

J. W. Hayami, S. D. Waldman, B. G. Amsden;

Queen's Univ., Kingston, ON, CANADA.

496

Effect of Scaffold Morphology on the Proliferation and Colonization of Seeded Chondrocytes

S. Guha Thakurta;

Univ. of Nebraska, Lincoln, NE.

497

Composite Mesh Incorporating Biointegrative Reticulated Elastomeric Matrix for Hernia Repair

A. Datta;

Biomerix, Somerset, NJ.

498

Development of a Bead Manipulator Module for a Biofabricator

M. Manhard, C. Thomas, K. Burg, T. Burg;

Clemson Univ., Clemson, SC.

499

PC12 Behavior in Modular Poly(Ethylene Glycol) Scaffolds: Effects of Stiffness and Protein Concentration

R. Scott, R. K. Willits;

Saint Louis Univ., St. Louis, MO.

500

Biomolecules Immobilization on Microfabricated Functional Hydrogels

R. T. S. Lam, P. L. Stiles, S. R. Nettikadan;

NanoInk Inc., Skokie, IL.

501

Characterization of Membrane Materials and Membrane Coatings for Bioreactor Units of Bioartificial Kidneys

M. Ni, Y. Zay, M. Ibrahim, F. Tasnim, J. Y. Ying, D. Zink;

Inst. of Bioengineering and Nanotechnology, Singapore, SINGAPORE.

502

Isotropic and Anisotropic Cryogel Matrices for Cartilage Tissue Engineering

A. Tripathi, A. Kumar;

Indian Inst. of Technology Kanpur, Kanpur, INDIA.

503

Synthesis and Characterization of Composite Biodegradable Hydrogel Systems for Controlled Pore Opening

A. M. Hawkins, T. A. Milbrandt, D. A. Puleo, J. Z. Hilt;

Univ. of Kentucky, Lexington, KY.

504

Cell Infiltration and Growth in a Low Density, Uncompressed Three-Dimensional Electrospun Nanofibrous Scaffold

B. Blakeney, A. Tambralli, J. Anderson, A. Andukuri, D. Lim, D. Dean, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

505

Rapid Production of a Tubular Dense Collagen Construct for Tissue Engineering

C. E. Ghezzi, B. Marelli, N. Muja, S. N. Nazhat;

McGill Univ., Montréal, QC, CANADA.

506

Bioceramic Nanocrystal Coating via Pickering Emulsion Route: Fabrication of Hydroxyapatite/Biodegradable Composite Microspheres for Injectable Cell Scaffold

T. Terada;

Dept. of Biology-Oriented Sci. and Technology, Kinki Univ., Kinokawa Wakayama, JAPAN.

507

Fabrication of Fiber Based 3D Tissue Engineering Scaffolds

T. He¹, N. M. Tambe¹, K. D. Sippel², J. Di¹, A. El-Shafei¹, N. A. Monteiro-Riviere¹, M. W. King¹;

¹North Carolina State Univ., Raleigh, NC, ²Inst. für Textiltechnik, RWTH-Aachen Univ., Aachen, GERMANY.

508

Endostatin-Producing Cartilaginous Constructs Using Collagen Hydrogels and Pre-Formed Collagen Sponge-Like Scaffolds

L. Jeng¹, B. R. Olsen², M. Spector³;

¹Massachusetts Inst. of Technology, Cambridge, MA, ²Brigham and Women's Hosp., Harvard Med. Sch., Boston, MA, ³VA Boston Hlth.care System, Boston, MA.

509

Optimization of Fiber Alignment Within Polycaprolactone Nerve Conduits

D. M. Minteer¹, Y. Lin¹, S. Pixley², K. G. Marra¹;

¹Univ. of Pittsburgh, Pittsburgh, PA, ²Univ. of Cincinnati, Cincinnati, OH.

510

Characterization and Cytocompatibility of Doxycycline Composite Scaffolds

M. E. Cortes, V. C. C. Trajano, K. J. R. Costa, R. D. Sinisterra;

UFMG, Belo Horizonte, MG, BRAZIL.

511

Mechanical Analysis of Poly(Ethylene Glycol) Diacrylate and Agarose Interpenetrating Network Hydrogels

D. A. Rennerfeldt, G. C. Ingavle, S. H. Gehrke, M. S. Detamore;

Univ. of Kansas, Lawrence, KS.

512

Printing of Biocompatible Polymers and their Composites for Biomedical Engineering

M. Rasekh¹, Z. Ahmad¹, R. Day², M. Edirisinghe¹;

¹Univ. Coll. London (UCL), London, UNITED KINGDOM, ²Windeyer Inst., Univ. Coll. London (UCL), London, UNITED KINGDOM.

513

Electrospun Biodegradable Polycaprolactone/Poly(1,4-Butylene Adipate-Co-Polycaprolactam) Hybrid Scaffold For Bone Tissue Engineering

S. T S, R. Balu;

Indian Inst. of Technology Madras (IITM), Chennai, INDIA.

514

Effect of Negative Poisson's Ratio of Polyurethane Scaffold on Chondrotyte Behavior with Mechanical Stimulus

S-W. Shin, Sr.¹, H-S. Roh¹, K-W. Park¹, J-B. Choi², J-C. Park³, J-K. Kim¹;

¹Inje Univ., Gimhae, KOREA, REPUBLIC OF, ²Hansung Univ., Seoul, KOREA, REPUBLIC OF, ³Yonsei Univ., Seoul, KOREA, REPUBLIC OF.

515

Fabrication of Chemically Crosslinked Gelatin Microspheres with Tunable Degradation Profiles

M. A. Serban, T. Knight, R. Payne;

Tengion, Inc, Winston-Salem, NC.

516

Highly Aligned Porous Biomaterials by Reverse Freeze Casting

S-W. Yook¹, H-E. Kim¹, Y-H. Koh²;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

517

Absorbable Solvent-Precipitated Foams and Applications Thereof

K. D. Gray, Jr., M. S. Taylor, R. T. Pace, J. T. Corbett, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

Modification of Three Dimensional Scaffolds for Tissue Engineering Applications

518

CS-Blood Hydrogel Adhesive for the Expansion and Controlled Differentiation of Stem Cells

I. Strehin, I. Wu, Q. Lu, J. Zhan, J. Elisseeff;

Johns Hopkins Univ., Baltimore, MD.

519

Hydroxyapatite Surface Nanoscaled characterization and Electrical Potential Functionalization to Engineer Osteoblasts Attachment and Generate Bone Tissue

Y. Dekhtyar, Sr.;

Riga Technical Univ., Riga, LATVIA.

520

Endothelial Progenitor Cell Adhesion and Growth on Peptide-Coated Electrospun Scaffolds

R. Shenkman, X. Wang, D. Heath, S. L. Cooper;

The Ohio State Univ., Columbus, OH.

521

Mesenchymal Stem Cell Chondrogenesis and Chondrocyte Response to Extracellular Matrix Molecules

E. E. Coates, J. P. Fisher;

Univ. of Maryland, College Park, MD.

522

Effects of FGF-1 and PEG Matrix Properties on 3D Fibroblast Invasion

S. Sokic, G. Papavasiliou;

Illinois Inst. of Technology, Chicago, IL.

523

Formation of Aggregated Alginate Constructs in a Tubular Perfusion System

A. B. Yeatts, C. N. Gordon, J. P. Fisher;

Univ. of Maryland, College Park, MD.

524

Implantable "Sensate" Medial Condyle Surface Replacement Allows Shear and Axial Load Sensing

J. S. Szivek, G. J. Heden, N. H. Diggins, C. P. Geffre, J. T. Ruth, L. D. Farrow;

Univ. of Arizona, Tucson, AZ.

525

Co-encapsulation of TGF-β1 into Negatively Charged Oligo(polyethylene glycol) Fumarate Hydrogels to Enhance Chondrogenesis of Bone Marrow Stromal Cells

M. E. Casper, M. Dadsetan, M. J. Yaszemski;

Mayo Clinic, Rochester, MN.

526

Scaffold Design for Functional Tissue Engineering and Cell-Based Gene Therapy Applications

A. M. Yousefi;

Miami Univ., Oxford, OH.

527

Influence of Fluid Flow on Porous Scaffold Structural Deformation

S. V. Madihally, J. Podichetty, D. Dhane;

Oklahoma State Univ., Stillwater, OK.

528

Electrospun Polyvinyl Alcohol/Cyclodextrin/Tobramycin Nanofibrous Matrix for Drug Delivery

P. Bhullar¹, W. Song¹, X. Jin¹, T. Shi¹, D. Markel², W. Ren¹;

¹Wayne state Univ., Detroit, MI, ²Detroit Med. Ctr./Providence Hosp. Orthopedic Surgery Residency Program, Detroit, MI.

529

Visible Light Crosslinkable Chitosan-based Hydrogels for Tissue Engineering Applications

Y. Hou¹, J. Hu¹, B. Wu², M. Lee¹;

¹Sch. of Dentistry, Univ. of California, Los Angele, Los Angeles, CA, ²Dept. of Bioengineering, Univ. of California, Los Angele, Los Angeles, CA.

530

Plasma Surface Modification of Electrospun Poly(ε-Caprolactone) Nanofibers and its Effect on Surface Bioactivity

J. E. Jones¹, D. Yan¹, H. Li¹, J. C. M. Lee¹, Q. Yu¹, X. Yuan², J. Sheng², G. Ma²;

¹Univ. of Missouri, Columbia, MO, ²Tianjin Univ., Tianjin, CHINA.

Self-Assembly in Tissue Engineering

531

A Fluorescent Method for Detecting Ligand Availability on the Surface of Self-Assembled Peptide Nanofibers

E. A. Verbus¹, J. S. Rudra¹, A. R. Urbach², J. H. Collier¹;

¹Univ. of Chicago, Chicago, IL, ²Trinity Univ., San Antonio, TX.

532

Directed Assembly of Microscale Particles by Acoustic Waves for Biomedical Applications

F. Xu;

Harvard Med. Sch., Cambridge, MA.

533

Directed Assembly of Microscale Hydrogels via Magnetics

F. Xu;

Harvard Med. Sch., Cambridge, MA.

534

Three-dimensional Constructs Induce High Cellular Activities for Protein and Cytokine Productions

K. Kadowaki, M. Matsusaki, M. Akashi;

Graduate Sch. of Engineering, Osaka Univ., Suita, JAPAN.

535

Osteogenic Differentiation of Human Mesenchymal Stem Cells Synergistically Enhanced by Biomimetic Peptide Amphiphiles Combined with Conditioned Media

J. Anderson, J. Vines, J. Patterson, H. Chen, A. Javed, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

537

Culture and Analysis of Adipocytes in Two and Three Dimensional Culture Configurations

L. M. Harris, A. B. Silvestrini, A. V. Janorkar;

Univ. of Mississippi Med. Ctr., Jackson, MS.

538

Effects of Hydroxyapatite Mineralization and EDC Cross-linking on the Response of Collagen Fibers to Tensile Loads

R. F. Banglmaier, T. Bou-Akl, P. VandeVord;

Wayne State Univ., Detroit, MI.

Spatially Patterned Biomaterials for Tissue Engineering

539

Maximizing Cellular Pattern Resolution in Biofabrication

L. Roudsari, E. Bland, M. Pepper, V. Seshadri, T. Burg, K. Burg;

Clemson Univ., Clemson, SC.

540

Decreased VEGF Synthesis by Lung Carcinoma Cells on Polymer Nanometer Surface Features

L. Zhang, T. J. Webster;

Brown Univ., Providence, RI.

541

Microfabrication of an Artificial Bruch’s Membrane for the Treatment of Age-Related Macular Degeneration

K. J. McHugh¹, M. Saint-Geniez², S. L. Tao³;

¹Boston Univ., Boston, MA, ²Schepens Eye Res. Inst. and Harvard Med. Sch., Boston, MA, ³The Charles Stark Draper Laboartory, Cambridge, MA.

542

Biodegradable Elastomeric Substrates with Concentric Microgrooves for Regulating MC3T3 Cell Behavior

K. Wang¹, L. Cai¹, L. Zhang², J. Dong², S. Wang¹;

¹The Univ. of Tennessee Knoxville, Knoxville, TN, ²North Carolina State Univ., Raleigh, NC.

543

Biodegradable Elastomeric Substrates with Micro-fabricated Grooves for Promoting Neurite Extension

L. Cai¹, L. Zhang², J. Dong², S. Wang¹;

¹The Univ. of Tennessee Knoxville, Knoxville, TN, ²North Carolina State Univ., Raleigh, NC.

544

Micropatterned Thermoresponsive Polymer Brush Surfaces for Preparation of Cell Sheets with Well-defined Alignment

H. Takahashi, M. Nakayama, T. Okano;

Tokyo Women's Med. Univ., Tokyo, JAPAN.

545

Alignment of 3D Nano-/Micro-Structured Silk Fibroin-Chitoson Scaffolds Using DEP for Tissue Engineering

L. Wang, T. Iyyanki, J. Hubenak, A. Mathur;

The Univ. of Texas, M. D. Anderson Cancer Ctr., Houston, TX.

546

In Vitro Assembly of Micropatterned Cell Sheets for Vascular Tissue Engineering

N. Patel, J. Cavicchia, B-m. Newby, G. Zhang;

Univ. of Akron, Akron, OH.

547

Engineered Microtopographies Direct Human Coronary Artery Cell Elongation and Orientation

C. M. Magin, A. Baah-Dwomoh, M. Showalter, M. Segal, A. Brennan;

Univ. of Florida, Gainesville, FL.

Tissue Engineered Scaffolds

548

Assembly of Functional Neovessels using a Stereolithographic Hydrogel Matrix

J. Jeong, V. Chan, C. Cha, P. Zorlutuna, R. Bashir, H. Kong;

Univ. of Illinois at Urbana-Champaign, Urbana, IL.

Strategies to Promote Vascularization of Tissue Engineered Constructs

549

Immobilized VEGF Fragment Promotes Microvasculature Formation in Poly(ethylene glycol) Diacrylate Hydrogels

J. E. Saik¹, J. E. Barbick¹, D. J. Gould¹, M. E. Dickinson², J. L. West¹;

¹Rice Univ., Houston, TX, ²Baylor Coll. of Med., Houston, TX.

550

Myocardial Protection and Angiogenic Synergism in Acute Myocardial Infarction Using Dual Growth Factor with Self-Assembling Peptide Nanofiber Hydrogel

J. Kim¹, Y. Park², Y. Jeong¹, S-h. Kim¹, S. Kim¹;

¹Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ²Korea Univ., Seoul, KOREA, REPUBLIC OF.

551

3D Microfluidic Tissue Model with Perfused Human Capillaries

M. L. Moya, Y-H. Hsu, C. C. W. Hughes, A. P. Lee, S. C. George;

Univ. of California, Irvine, Irvine, CA.

552

Modular Poly(Ethylene Glycol) Scaffolds with Multiple Levels of Porosity for Cell Transplantation and Vascularization

D. L. Elbert, A. W. Smith, M. J. Stork, P. K. Nguyen, I. R. Efimov;

Washington Univ., St. Louis, MO.

553

FEM Optimization of Sustained VEGF Delivery for Angiogenesis Applications

E. Martinez, P. Lofti, S. Dash, M. Romero-Ortega;

Univ. of Texas at Arlington, Arlington, TX.

554

Parsing Inflammatory Cues in Angiogenesis

A. L. Zachman¹, S. W. Crowder¹, H. K. Kleinman², J. B. Kohn³, H-J. Sung¹;

¹Vanderbilt Univ., Nashville, TN, ²Natl. Inst. of Dental and Craniofacial Res., Bethesda, MD, ³New Jersey Ctr. for Biomaterials, Rutgers Univ., Piscataway, NJ.

555

Quantitative Fluorescence Imaging for Tissue Engineered Systems

E. Bland, K. Burg;

Clemson Univ., Clemson, SC.

556

Localized Delivery of bFGF from Elctrospun Scaffolds for Guided Angiogenesis

X. Vial, R. B. Montero, S. Pham, F. M. Andreopoulos;

Univ. of Miami, Coral Gables, FL.

557

Engineering Hydrogel Scaffold for Rapid and Functional Vascularization

G. Sun;

Johns Hopkins Univ., Baltimore, MD.

558

Three-Dimensional Morphological Quantification to Understand Vasculogenesis

J. Rytlewski, S. Rajput, L. Nguy, L. Suggs;

Univ. of Texas at Austin, Austin, TX.

559

Endothelial Cell Response to Vascular Endothelial Growth Factor on Hydroxyapatite Surfaces

K. D. Solomon, J. L. Ong;

Univ. of Texas at San Antonio, San Antonio, TX.

Valves and Stents

560

Electrospun Scaffolds with Gradient Morphology for Use in Endovascular Aortic Aneurysm Repair

J. Massey¹, S. R. Bailey², M. Agrawal¹;

¹Univ. of Texas at San Antonio, San Antonio, TX, ²Univ. of Texas Hlth.Sci. Ctr. at San Antonio, San Antonio, TX.

561

Neomycin-Enhanced Carbodiimide Crosslinking for Glycosaminoglycan Stability in Bioprosthetic Heart Valves

J. G. W. Leong;

Clemson Univ., Clemson, SC.

562

HDL-Adsorbing Hydrophilic Surfaces: Potential as Blood-Compatible Endothelium Regenerating Coatings.

M. L. W. Knetsch, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.

563

Influence of Zn Content in Mgal3 and Mgal9 Alloys on Initial Corrosion Behavior in Human Blood

J. Geis-Gerstorfer, C. Schille, E. Schweizer, F. Rupp, L. Scheideler, A. Nolte, H-P. Wendel;

Univ. of Tuebingen, Tuebingen, GERMANY.

564

Nitinol Corrosion Ions Inhibit α-actin Expression and Decrease Aspect Ratio of Rat Vascular Smooth Muscle Cells in vitro

B. H. Winn;

Clemson Univ., Clemson, SC.

565

Electrochemically-assisted Functionalization of a 316L Stainless Steel Surface: Towards the Minimization of In-stent Restenosis

H. Dadafarin, L. Li, E. C. Davis, S. Omanovic;

McGill Univ., Montreal, QC, CANADA.

Scaffolds for Cardiovascular and Musculosketetal Organ Regeneration

566

Online Monitoring of Tissue-Engineered Cartilage Development in a Dynamic Compression Bioreactor

J. Popp¹, J. Roberts², S. Bryant², T. Quinn¹;

¹Natl. Inst. of Standards and Technology, Boulder, CO, ²Univ. of Colorado, Boulder, CO.

567

Gene Regulation in MMP-Degradable Carriers Differs Between Fibroblasts and Mesenchymal Stem Cells

D. M. Doroski, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.

568

Phenotype Characterization of Human Coronary Artery Smooth Muscle Cells Using Cyclic Mechanical Strain

S. Sharifpoor¹, C. A. Simmons¹, R. S. Labow², J. P. Santerre¹;

¹Univ. of Toronto, Toronto, ON, CANADA, ²Univ. of Ottawa, Ottawa, ON, CANADA.

569

Postoperative Tissue Adhesion Barrier Gel Based on Hyaluronic Acid and Alginate

S. Na¹, S. Oh¹, K. Song², J. Lee¹;

¹Hannam Univ., Daejeon, KOREA, REPUBLIC OF, ²Chungnam Natl. Univ., Daejeon, KOREA, REPUBLIC OF.

570

Direct Co-Culture of Endothelial Progenitor Cells with Human Mesenchymal Stem Cells on Nanopatterned Surfaces

C. E. Fernandez, F. Zhao, W. M. Reichert;

Duke Univ., Durham, NC.

Dynamically Responsive Biomaterials

571

Bicomponent Selectively-Absorbable Hernia Mesh for Improved Wound Healing

S. J. Peniston, G. T. Hilas, M. S. Taylor, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

572

Smart Coating of Poly(N-isopropylacrylamide)-Based Block Copolymers for Cell Sheet Harvest

M. Nakayama¹, N. Yamada², H. Kanazawa², T. Okano¹;

¹Tokyo Women's Med. Univ., Tokyo, JAPAN, ²Keio Univ., Tokyo, JAPAN.

573

Iron Oxide Nanocomposite Sol-Gel Systems for Remote Controlled Drug Release

A. M. Hawkins, C. E. Bottom, D. A. Puleo, J. Z. Hilt;

Univ. of Kentucky, Lexington, KY.

574

Rapid, pH-dependent Self Healing Hydrogels

A. Phadke, C-C. Hsu, C. Zhang, G. Arya, M. Tauber, S. Varghese;

Univ. of California, San Diego, La Jolla, CA.

575

Design of Smart Biodegradable Materials with Dynamically Tunable Stiffness for Control of Cell Functions

K. Uto, M. Ebara, T. Aoyagi;

Natl. Inst. for Materials Sci., Tsukuba, JAPAN.

576

Enzymatically Triggered Microcapsules For Water-soluble Drug Delivery Applications

X. Cheng, S. A. Desai, K. Carson, M. L. Kimmel;

Southwest Res. Inst., San Antonio, TX.

577

Temporal Control of Mechanical Properties of Degradable Poly(β-amino ester) Networks

D. Safranski¹, D. Weiss², J. Clark², W. R. Taylor², K. Gall¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Emory Univ., Atlanta, GA.

578

Shear-Induced Adhesion in Mussel Foot Protein-1 Films

R. Schur, R. Andresen-Eguiluz, D. Gourdon;

Cornell Univ., Ithaca, NY.

579

Layer-by-Layer Assembly of Biocompatible Polyelectrolytes on pH and Temperature Responsive Microgels

E. Costa¹, A. Aguiar-Ricardo², P. T. Hammond¹;

¹Massachusetts Inst. of Technology, Cambridge, MA, ²REQUIMTE/CQFB, Faculdade de Ciências e Tecnologia, Univ.e Nova de Lisboa, Caparica, PORTUGAL.

580

Thermoresponsive Cell Culture Surfaces for Promoting Cell Adhesion

J. Kobayashi, M. Nishi, Y. Akiyama, M. Yamato, T. Okano;

Tokyo Women's Med. Univ., Tokyo, JAPAN.

581

Novel Injectable Thermo-Responsive Complexes For Prolonged Nitric Oxide Delivery

J. Yang, R. Lith, G. A. Ameer;

Northwestern Univ., Evanston, IL.

582

Light-triggered Phase Transitions in Nanofiber-Nanorod Composites

V. Ramanan, K. C. Hribar, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

583

Smart Biodegradable POSS-Polycaprolactone PolyUrethanes

E. Huitron-Rattinger;

Universidad Nacional Autonoma de Mexico, Cuernavaca, MEXICO.

584

Preparation of PIPAAm Modified Silicone Elastomer by Using Electron Beam Irradiation

Y. Akiyama;

Inst. of Advanced BioMed. Engineering and Sci., 8-1 Kawadacho,, JAPAN.

Engineering Instructive Cues into Biomaterials

585

Effect of Bioactive Surface Coating on Protein Adsorption, Bone Cell Differentiation and Immune Response

Aniket, I. Marriott, A. El-Ghannam;

The Univ. of North Carolina at Charlotte, Charlotte, NC.

586

Genipin-crosslinked Chitosan/Poly(lysine) Films to Promote Oligodendrocyte Progenitor Cells’ Attachment and Proliferation In-vitro

M. Mekhail, G. Almazan, M. Tabrizian;

McGill Univ., Montreal, QC, CANADA.

587

Effect of Polyelectrolyte Multilayer Assembly on Accessibility of Immobilized Growth Factor

N. M. Shah¹, F. Gorouhi¹, B. J. Wood¹, A. Agarwal², J. Covert¹, R. R. Isseroff¹, N. L. Abbott², C. J. Murphy¹;

¹Univ. of California, Davis, Davis, CA, ²Univ. of Wisconsin-Madison, Madison, WI.

588

Bulk and Surface Covalent Immobilization of ECM Molecules on Hydrogels formed by Michael-type Addition

A. Sen, R. C. Cribb, J. Lee, K. Webb;

Clemson Univ., Clemson, SC.

589

Synthesis and Collection of Collagen Nanotubes for Biomaterials Application

D. Kalaskar, J. Landoulsi, C. Dupont-Gillain, S. Demoustier;

Université catholique de Louvain, Louvain-la-Neuve, BELGIUM.

590

Immobilization of Epidermal Growth Factor on Titanium

Y. Ito;

Riken Advanced Sci. Inst., Wako-shi, JAPAN.

591

Morphology Tuning of Chitosan Films via Electrochemical Deposition on Metallic Substrates

L. Altomare, F. Rubini, A. Cigada, R. Chiesa, L. De Nardo;

Politecnico di Milano, Milan, ITALY.

Responsive Biomaterials: Exploiting Biological Signals

592

Thermosensitive Hydrogels Induce Cardiosphere Derived Cells Differentiation into Cardiac Lineage In Vitro

Z. Li, J. Guan;

Ohio State Univ., Columbus, OH.

593

Controlling the Adhesion and Differentiation of Mesenchymal Stem Cells Using Cell Responsive, Hyaluronic Acid-based, Doubly-Crosslinked Networks

A. K. Jha, X. Jia;

Univ. of Delaware, Newark, DE.

594

Temperature-Controlled Modulation of Fibrin Matrix Properties

A. S. C. Soon, C. S. Lee, T. H. Barker;

Georgia Inst. of Technology, Atlanta, GA.

595

Dual Coating Proteins Silanized to Titanium Alloy: A Bioinductive Surface for Fibroblasts

C. J. Pendegrass, M. El-Husseiny, G. Blunn;

Univ. Coll. London, Stanmore, Middlesex, UNITED KINGDOM.

596

Increased Proteoglycan Syntheses in Primary Human and Bovine Chondrocytes in Biomimetic PEG Hydrogels Containing Type I Collagen and Hyaluronic Acid Signaling Motifs

L. Smith¹, D. McBurney², A. Ganos¹, A. Nugent², W. Horton², M. L. Becker¹;

¹Univ. of Akron, Akron, OH, ²Northeastern Ohio Universities Coll. of Med. and Pharmacy, Rootstown, OH.

597

Protein Adsorption On Poly(Methacrylic Acid) Modified Silicon Nanowire Arrays

L. Yuan¹, Q. Yu², H. Chen¹, Y. Zhang², H. Wang¹;

¹Soochow Univ., Suzhou, CHINA, ²Wuhan Univ. of Technology, Wuhan, CHINA.

Optimization and Characterization of Nanoparticle Biocompatibility

598

Vascular Smooth Muscle Cell Mechanics in Response to Gold Nanoparticles

W. McAllister, L. Wiles, P. Kerscher, J. Turbeville, C. Kitchens, D. Dean;

Clemson Univ., Clemson, SC.

599

Intracellular Degradation and Distribution of Size-Controlled Antigen-Encapsulated Biodegradable Nanoparticles

F. Shima, T. Akagi, M. Akashi;

Osaka Univ., Suita, JAPAN.

600

Preparation of PLLA Nanocomposites Containing Magnesium Hydroxide for Neutralization of an Acidic Environment in Biodegradable Polymers

C. Kum, J. Choi, K. Park, D. Han;

Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF.

601

Transport of Dendritic Nanoparticles across the Porcine Buccal Mucosa: Implications for Buccal Administration of Dendrimer-Based CNS Nanomedicines

Q. Yuan¹, Y. Fu², W. Kao², D. Janigro³, H. Yang¹;

¹Virginia Commonwealth Univ., Richmond, VA, ²Univ. of Wisconsin-Madison, Madison, WI, ³Cleveland Clinic Fndn., Cleveland, OH.

602

The Conjugation of Amyloid Beta Protein on the Gold Colloidal Nanoparticles’ Surface

K. Yokoyama;

SUNY Geneseo Coll., Geneseo, NY.

603

Green Synthesis of Gold Quantum Dots and Cadmium Free Quantum Dots for Cancer Cell Imaging: Haemocompatibility and Cytotoxicity Evaluation.

C. Durgadas, D. Sreenivasan, C. Sharma;

Sree Chitra Tirunal Inst. for Med. Sci. and Technology, Trivandrum, INDIA.

604

Surface Modifications of Poly(N-isopropylacrylamide) Microgels for Targeted Drug Delivery

H-Y. Tsai, M. Yates;

Univ. of Rochester, Rochester, NY.

605

Analysis of Cellular Adhesion on Substrate Containing Multi-Walled Carbon Nanotube (MWCNTs)

M. M. Machado¹, A. O. Lobo², S. C. Ramos², E. J. Corat², M. A. F. Corat

¹; ¹CEMIB/UNICAMP, Campinas, BRAZIL, ²INPE, São José dos Campos, BRAZIL.

606

Analysis of Cellular Spreading on Substrate Containing Multi-Walled Carbon Nanotube (MWCNTs)

M. M. Machado¹, A. O. Lobo², S. C. Ramos², E. J. Corat², M. A. F. Corat¹;

¹CEMIB/UNICAMP, Campinas, BRAZIL, ²INPE, São José dos Campos, BRAZIL.

607

Study of Mesenchymal Stem Cell Function on Zinc Oxide Nanoparticles

A. C. Jayasuriya, A. H. Jayatissa;

Univ. of Toledo, Toledo, OH.

Translational Research in Nano-biomaterials

608

Nitric Oxide-Releasing Nanoparticle/Polymer Microfiber Composites

J. A. Nash, P. N. Coneski, D. A. Riccio, M. H. Schoenfisch;

Univ. of North Carolina at Chapel Hill, Chapel Hill, NC.

609

Intravenously Administered Nanoparticles to Control Bleeding

A. Shoffstall¹, K. Kelly², J. Ustin², D. Campbell¹, L. Wu¹, E. Lavik¹;

¹Case Western Reserve Universitiy, Cleveland, OH, ²Metro Hlth., Cleveland, OH.

610

Acid Etched Porocoat® of CoCrMo for Biological Fixation

W. Tong, L. Salvati;

DePuy Orthopaedics, Warsaw, IN.

611

Increased Cardiomyocyte Uptake of N-acetylglucosamine-Decorated Nanoparticles

W. D. Gray¹, X. Ning², J. C. Sy¹, M. E. Davis¹, N. Murthy¹;

¹Georgia Inst. of Technology and Emory Univ., Atlanta, GA, ²Georgia Inst. of Technology, Atlanta, GA.

612

Nanofibrous PLA Mesh is Wound Adherent and Hemostatic in Pig Liver Resection Model

W. H. Velander¹, J. Calcaterra¹, R. Spretz², S. Noriega², G. Larsen², M. A. Carlson³, I. I. Pipinos³, J. M. Johanning³;

¹Univ. of Nebraska, Lincoln, NE, ²LNK Chemsolutions LLC, Lincoln, NE, ³Univ. of Nebraska Med. Ctr., Omaha, NE.

613

The Role Of Surface Topography On Cellular Attachment To Poly(L Lactic Acid) Electrospun Fibers

R. F. Ostapoff, A. Throm, S. Gleiman;

Covidien, North Haven, CT.

614

Assessment of a Decellularized Porcine Diaphragm and Gold Nanomaterial Composite as a Tissue Scaffold for Wound Healing

M. J. Cozad, S. L. Bachman, S. A. Grant;

Univ. of Missouri, Columbia, MO.

615

Antioxidant Hydrogels for Cellular Encapsulation Using Cerium Oxide Nanoparticles

J. D. Weaver, C. L. Stabler;

Univ. of Miami, Miami, FL.

616

Evaluating Bacterial Colonization of Nanomodified Endotracheal Tubes in a Bench Top Airway Model

M. Machado¹, K. Tarquinio², T. Webster¹;

¹Brown Univ., Providence, RI, ²Rhode Island Hosp., Providence, RI.

617

Microparticle-Mediated Nox2-Sirna Therapy for Preventing Cardiac Dysfunction Following Myocardial Infarction

I. Somasuntharam¹, J. Sy¹, G. Seshadri¹, N. Murthy¹, M. Davis²;

¹Georgia Inst. of Technology, Atlanta, GA, ²Emory Univ., Atlanta, GA.

618

Integration of Silver-Impregnated Polymeric Multilayers onto Biological Tissues to Provide Antibacterial Activity

A. Agarwal, K. M. Guthrie, C. J. Czuprynski, M. J. Schurr, J. F. McAnulty, C. J. Murphy, N. L. Abbott;

Univ. of Wisconsin, Madison, WI.

619

Biodegradable Nanoparticles Containing Benzopsoralens and Vascular Function in Pathological Skin Disorders

A. J. Gomes¹, L. O. Lunardi², F. H. Caetano², A. E. H. Machado³, A. F. Oliveira⁴, L. M. Bendhack⁵, C. N. Lunardi¹;

¹FCE-UnB, Brasilia, BRAZIL, ²UNESP, Rio Claro, BRAZIL, ³UFU, Uberlandia, BRAZIL, ⁴IQBF, Braga, PORTUGAL, ⁵FCFRP-USP, Ribeirão Preto, BRAZIL.

620

Nitric Oxide-releasing TEOS Nanoparticles Antitumoral Action Om Melan-a Cells

A. J. Gomes¹, E. M. Espreafico², E. Tfouni³;

¹FCE-UnB, Brasilia, BRAZIL, ²FMRP-USP, Ribeirão Preto, BRAZIL, ³FFCLRP-USP, Ribeirão Preto, BRAZIL.

621

Bioengineered Controlled Delivery System for the Treatment of Acute Liver Failure

S. Kobsa, G. Wu, B. Liu, H. G. Cohen, E. S. Swenson, W. M. Saltzman;

Yale Univ. Sch. of Med., New Haven, CT.

622

Characterization of Nano-scaled Cellulose Surface Area and Pore Size

J. Guo, J. M. Catchmark;

The Pennsylvania State Univ., University Park, PA.

Alternative Platforms for Pharmacologic Administration

623

Novel Multimeric siRNA-XDNA Nanostructures for Precise Multifunctional Synergistic Therapy

C. Ke, S. Um, D. J. Irvine;

Massachusetts Inst. of Technology, Cambridge, MA.

624

Size Dependent Biocidal Action of Nitric Oxide-Releasing Silica Nanoparticles

A. W. Carpenter, M. H. Schoenfisch;

Univ. of North Carolina at Chapel Hill, Chapel Hill, NC.

625

Lyotropic Lipids of the Endogenous, n-Acylethanolamide Variety for Drug Delivery to Ocular Tissue

F. Lasowski¹, H. Sheardown¹, M. Moghaddam²;

¹McMaster Univ., Hamilton, ON, CANADA, ²CSIRO, Sydney, AUSTRALIA.

626

Encapsulation of Antigens into Microparticles Results in Subunit Dosage Sparing Capabilities

J. H. Wilson Welder, L. Huntimer, K. A. Ross, B. Carrillo-Conde, L. Pruisner, B. Narasimhan, M. J. Wannemuehler;

Iowa State Univ., Ames, IA.

627

Radiopaque Microspheres for Improved Transarterial Chemical Embolization of Tumors.

K. Saralidze, M. L. W. Knetsch, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.

628

Development of a Poly(lactic acid) Poly(ethylene glycol) Nanoparticle for Delivery of Vitamin D3 to Severe Asthmatics

M. V. Scionti;

Villanova Univ., Villanova, PA.

629

In Vitro and In Vivo Evaluation of Hydroxyzine Hydrochloride Microcapsules for Skin Delivery

C. Rizkalla, R. Aziz, I. Soliman;

Faculty of Pharmacy, Cairo Univ., Egypt, Cairo, EGYPT.

630

Synthesizing Calcium Alginate Nanoparticles via a New Interfacial Cross-linking Technique

P. Singh, J. Nesamony;

Univ. of Toledo, Toledo, OH.

631

Controlled Photoinitiated Nitric Oxide Release from S-nitroso-N-acetyl-DL-penicillamine Derivatized Silicone Rubber (SNAP-SR)

M. C. Frost, G. E. Gierke, M. Starrett, M. Nielsen;

Michigan Technological Univ., Houghton, MI.

632

AS-ODN Delivery into Mammalian Cells Using High Hydrostatic Pressurized Cationic Liposome

T. Kimura, A. Sano, K. Nam, Y. Sasaki, K. Akiyoshi, A. Kishida;

Tokyo Med. and Dental Univ., Tokyo, JAPAN.

633

Polysialic Acid-Based Nanoparticles for Systemic Drug Delivery

N. Zhang, C. J. Schweikert, Z. Balmuth-Loris, R. A. Bader;

Syracuse Univ., Syracuse, NY.

Diabetes Care / Insulin Delivery

634

Nanocomplexes System Based on Lithocholic acid-Modified Exendin-4 and Glycol Chitosan Bearing β-Cyclodextrin for the Treatment of Type 2 Diabetes.

H. Jang¹, S. Son², S. Chae², K. Lee², J. Park¹;

¹KyungHee Univ., Suwon, KOREA, REPUBLIC OF, ²SungKyunKwan Univ., Suwon, KOREA, REPUBLIC OF.

635

Enhanced Rat Islet Function and Viability within a Biomimetic Self-Assembled Nanomatrix Gel

D. Lim¹, S. Antipenko¹, N. Hadley¹, W. Cui¹, J. Thompson¹, J. Corbett², H-W. Jun¹;

¹Univ. of Alabama at Birmingham, Birmingham, AL, ²Med. Coll. of Wisconsin, Milwaukee, WI.

636

Developing Hydrogel Systems for the Formation of Islets of Langerhans from Single β-Cells

X. Liu, X. Li, X. Wen;

Clemson Univ., Charleston, SC.

637

Correlating Regional Hypoxia to Reduction in Insulin Secretion in Encapsulated Pancreatic β-cell Aggregates

M. L. Skiles;

Univ. of South Carolina, Columbia, SC.

Drug Delivery from Implant Surfaces

638

Toward an Antimicrobial Coated External Fixation Pin

T. R. Meyer, B. Luchsinger, M. Schallenberger;

Bacterin Intl., Inc., Belgrade, MT.

639

Osseointegration of Silver Treated Titanium Alloy

M. J. Coathup¹, J. Shawcross², C. Scarsbrook¹, M. Korda¹, A. Hanoun¹, M. Pickford², P. Agg², G. W. Blunn¹;

¹Univ. Coll. London, Stanmore, Middlesex, UNITED KINGDOM, ²Accentus Med., Didcot, UNITED KINGDOM.

640

Electro-deposition of Antimicrobial Silver Coatings on Stainless Steel Implants

A. Bandyopadhyay;

Washington State Univ., Pullman, WA.

641

Drug Eluting Stents: Controlled Drug Release Using Magnesium Alloy Coatings

C. E. Macias¹, G. Mani², M. Feldman³, C. Agrawal¹;

¹Univ. of Texas at San Antonio, San Antonio, TX, ²Univ. of South Dakota, Sioux Falls, SD, ³Univ. of Texas Hlth.Sci. Ctr. at San Antonio, San Antonio, TX.

642

A Temperature-Sensitive Drug Release System Based on Phase-Change Materials

Y. Zhang, S-W. Choi, Y. Xia;

Washington Univ. in St. Louis, St. Louis, MO.

643

Comparison of Antimicrobial Needleless I.V. Connectors in a Septum Contamination Assay

M. Schallenberger, B. Luchsinger, T. Meyer;

Bacterin Intl. Inc., Belgrad, MT.

644

Antibiotic Release from HA-coated Porous Metal Structures Under Static and Dynamic Conditions

A. S. LaCroix, S. Sundaramurthy, G. Gupta;

Biomet Inc., Warsaw, IN.

646

Management of the Infected Arthroplasty Using Antibiotic-Loaded Hydroxyapatite Blocks Combined With Cement Spacer

Y. Mochida, K. Ishii, K. Harigane, N. Taki, Y. Akamatsu, N. Mitsugi, T. Saito;

Yokohama City Univ., Yokohama, JAPAN.

647

Commercial Collagen Matrices for In Vitro Diagnostic Bioartificial Arteries

T. W. Steele;

Nanyang Technological Univ., Singapore, SINGAPORE.

648

A Drug Eluting, Osseointegrative Phospholipid Coating for Titanium Implants

D. A. Prawel, K. C. Popat, S. P. James;

Colorado State Univ., Ft. Collins, CO.

649

Application of α-Cristobalite and β-Rhenanite as Drug Delivery Systems

H. Pacheco;

Univ. of North Carolina at Charlotte, Charlotte, NC.

650

Viability and Differentiation of BMP-2 on W-20-17 cells in the Presence of Vancomycin

H. Doty, J. D. Bumgardner, W. O. Haggard;

Univ. of Memphis, Memphis, TN.

651

Synthesis and Characterization of Dendrimer-Drug Nanodevices to Target Periprosthetic Inflammation

W. Ren, A. Bosnjakovic, M. Mishra, T. Shi, R. M. Kannan;

Wayne State Univ., Detroit, MI.

652

Silica Xerogel-Chitosan Hybrid Coating on Porous Hydroxyapatite Scaffold for BMP Loading

S-H. Jun¹, E-J. Lee¹, J-H. Jang², H-E. Kim¹;

¹Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ²In-Ha Univ., Incheon, KOREA, REPUBLIC OF.

653

Thermoreversible PLGA-g-PEG Hydrogels Containing Hydroxyapatite for Potential Lipid Growth Factor Delivery

G. Lin, L. Cosimbescu, N. Karin, B. Tarasevich;

Pacific Northwest Natl. Lab., Richland, WA.

654

Dense Titanium Implants Embedded with Growth Factors

H-D. Jung, E-J. Lee, H-E. Kim;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

655

Preparation of Polyvinyl Alcohol (PVA) Microspheres Using Freeze-thaw Cycling Methods

D. Buzas¹, W. Song¹, X. Jin¹, T. Shi¹, D. Markel², W. Ren¹;

¹Wayne State Univ., Detroit, MI, ²Detroit Med. Ctr./Providence Hosp. Orthopedic Surgery Residency Program, Detroit, MI.

Biologically Derived Materials

656

Rat Adipose Derived Stem Cell (Rasc) Adhesion and Viability on Non-Cross-Linked Porcine Acellular Dermal Matrix (Ncl-PADM) In Vitro

T. S. Iyyanki;

The Univ. of Texas, M.D Anderson Cancer Ctr., Houston, TX.

657

Chondocytes From Human, Horse, Camel, Dog, and Cat Articular Cartilage Propagated on Microcarrier Spinner Culture Respond to Pro-Inflammatory Stimuli

M. W. Grzanna, L. F. Heinecke, A. Y. Au, S. L. Ownby, A. C. Mrozinski, C. G. Frondoza;

Nutramax Lab., Inc., Edgewood, MD.

658

Chinese Yam-Derived Adhesive for Tissue Engineering

L. Xia, S. Lenaghan, A. Wills, M. Zhang;

Univ. of Tennessee, Knoxville, TN.

659

Fibroblast-derived, ECM-enriched Biomaterials for Use in Nerve Repair.

M. B. Christensen, P. A. Tresco;

Univ. of Utah, Salt Lake City, UT.

660

Effect of Solvent Acids on Physical Properties and Cell Attachment to Chitosan Microsphere-based Scaffolds

R. E. Manning;

Univ. of Memphis, Memphis, TN.

661

An Investigation of NIH3T3 Cell Adhesion and Transfection on Glycol-Chitosan-Based Multilayered Films

C. Holmes¹, P. O. Bagnaninchi², M. Tabrizian¹;

¹McGill Universiy, Montreal, QC, CANADA, ²MRC Ctr. for Regenerative Med., Edinburgh, UNITED KINGDOM.

662

NanoSPONGE™ Crosslinked Natural Biopolymers Matrix

G. Ritter, C. Nataraj, J. Kirk;

Nanotherapeutics, Alachua, FL.

663

Biomimetic Aggrecan Based on a Polyacrylic Acid (PAA) Core and Chondroitin Sulfate (CS) Bristles

N. Ganesh¹, S. Sarkar¹, E. Vresilovic², M. Marcolongo¹;

¹Drexel Univ., Philadelphia, PA, ²Penn State Univ., Hershey, PA.

664

Bioabsorbable Hydrogel Made of Hydroxyapatite Functionalized Microspherelike Bacterial Cellulose Particles for Cartilage and Bone Tissue Regeneration

Y. Hu, J. M. Catchmark, E. A. Vogler`;

Pennsylvania State Univ., University Park, PA.

665

HPGuar Provides a Therapeutic Glycocalyx for Superior Tissue Lubrication

L. F. Springer¹, R. E. Baier¹, A. E. Meyer¹, H. A. Ketelson², D. L. Meadows²;

¹Univ. at Buffalo, Buffalo, NY, ²Alcon Res. Ltd., Fort Worth, TX.

666

Genipin-Crosslinked Nano-Fibrous Chitosan Membranes: Preliminary Testing For Use as GTR Membranes

P. A. Norowski, Jr.¹, W. C. Clem², P. C. Adatrow³, W. O. Haggard¹, J. D. Bumgardner¹;

¹Univ. of Memphis, Memphis, TN, ²Wright Med. Technology, Arlington, TN, ³Univ. of Tennessee Hlth.Sci. Ctr., Memphis, TN.

667

Mechanical Property Improvements to Chitosan through Disulfide Bonds

K. B. Miles, H. W. T. Matthew;

Wayne State Univ., Detroit, MI.

668

The Stability and Biocompatibility of Electrospun Collagen Using Common Cross-linking Agents

G. Portocarrero, P. Mashi, D. Pandya, S. Amara, G. Collins, T. Livingston Arinzeh;

New Jersey Inst. of Technology, Newark, NJ.

669

Gelatin-Ovalbumin Hybrid Hydrogels: Characterization and their Potential as a Dual Growth Factor Delivery Device

T. Horseman, A. Whittington;

Virginia Polytechnic Inst. and State Univ., Blacksburg, VA.

Biologically Inspired Biomaterials Approaches for Cancer Research

670

Electrospun Fiber-Glia White Matter Mimetics

A. Hissong¹, S. Rao¹, J. Larison¹, J. Johnson¹, A. Sarkar², J. Lannutti¹, J. Winter¹;

¹The Ohio State Univ., Columbus, OH, ²Univ. of Arkansas for Med. Sci., Little Rock, AR.

671

Brain Mimetic Hydrogels for Investigating Glioblastoma Multiforme Migration in 3D

S. S. Rao¹, J. DeJesus¹, A. Sarkar², J. O. Winter¹;

¹The Ohio State Univ., Columbus, OH, ²Univ. of Arkansas, Little Rock, AR.

672

Uptake and Migration of Tumor Cells in Response to Hybrid Polymer-Peptide Self-Assembled Nanoparticles

H. Ardalani, A. E. Mercado, J. Ma, X. He, E. Jabbari;

Univ. of South Carolina, Columbia, SC.

Engineering Therapeutic Delivery from Biomaterial Scaffolds

673

Antimicrobial-Loaded Microhydrogels Self-Assembled on Polymeric Nanofiber Scaffolds

Q. Wang, R. Junka, X. Yu, M. Libera;

Stevens Inst. of Technology, Hoboken, NJ.

674

Controlled Therapeutic Release from a Nucleic Acid Aptamer Functionalized Gold Nanoparticle Platform

P. Sundaram¹, J. Wower², M. E. Byrne¹;

¹Biomimetic & Biohybrid Materials, BioMed. Devices, and Drug Delivery Lab., Dept. of Chemical Engineering, Auburn Univ., Auburn, AL, ²Dept. of Animal Sci., Auburn Univ., Auburn, AL.

675

Effects of Local Delivery of Antibiotics from Chitosan Constructs on Hemostasis

J. A. Jennings¹, J. K. Smith¹, H. Speich², L. Jennings², S. P. Noel¹, J. D. Bumgardner¹, W. O. Haggard¹;

¹Univ. of Memphis, Memphis, TN, ²Univ. of Tennessee Hlth.Sci. Ctr., Memphis, TN.

676

Multifunctional Block Copolymer Nanoparticles for Controlled Release of Bone Morphogenetic Protein 2

L. Xiao, A. C. Greene, K. L. Kiick, X. Jia;

Univ. of Delaware, Newark, DE.

677

Porous EH and EH-PEG Scaffolds as Gene Delivery Vehicles to Skeletal Muscle

M. O. Wang¹, J. A. Thompson¹, E. E. Falco¹, J. M. Chetta¹, D. M. Yoon¹, E. Z. Li¹, M. M. Kulkami², S. B. Shah¹, A. Pandit², J. Roth³, J. P. Fisher¹;

¹Univ. of Maryland, Coll. Park, College Park, MD, ²Natl. Univ. of Ireland, Natl. Ctr. for BioMed. Engineering Sci., Galway, IRELAND, ³Univ. of Kentucky Coll. of Med., Lexington, KY.

678

Hybrid Biomimetic Nanomatrix for Cardiovascular Applications

A. Andukuri, A. Tambralli, J. M. Anderson, D. R. Dean, B. C. Brott, H-W. Jun;

Univ. of Alabama at Birmingham, Birmingham, AL.

679

Hierarchical Nanostructured Polymer Films Enhance Protein and Antibody Permeability

K. R. Kam;

Univ. of California, San Francisco, San Francisco, CA.

680

Effect of Hydrophobicity on Release of Hydrophilic Therapeutics from Hydrogel-Electrospun Fiber Mat Composites

N. Han, P. Bradley, J. Johnson, K. Parikh, A. Hissong, J. Lannutti, J. Winter;

The Ohio State Univ., Columbus, OH.

681

Neuron-specific Polymeric Micelle as a siRNA Delivery Carrier for CNS Regeneration

J. Zhang, K. Webb, J. Lee;

Clemson Univ., Clemson, SC.

682

Controlled Release of Bfgf from Chemically-Crosslinked Chitosan/Pluronic Hydrogel Containing Heparin

H. Kim, J. Choi, Y. Son, S. Yoon, E. Jo, H. Yoo;

Kangwon Natl. Univ., Chuncheon, KOREA, REPUBLIC OF.

683

Controllable Immobilization of Heparin onto Electrospun Poly(ε-caprolactone)/Gelatin Fibers for Growth Factor Delivery

J. Lee, J. J. Yoo, A. Atala, S. Lee;

Wake Forest Inst. for Regenerative Med., Winston-Salem, NC.

684

Drug-encapsulated Super Stiff Poly(ethylene glycol) hydrogel for Stem Cell Mobilization

Y. Liang¹, T. W. Jensen¹, E. J. Roy¹, C. Cha¹, R. J. DeVolder¹, R. E. Kohman², B. Zhang¹, K. B. Textor¹, L. A. Rund¹, L. B. Schook¹, Y. Tong³, H. Kong¹;

¹Univ. of Illinois at Urbana-Champaign, Urbana, IL, ²Boston Univ., Boston, MA, ³Natl. Univ. of Singapore, Singapore, SINGAPORE.

685

Increased Lymphatic Growth with Nitric Oxide and Electrospun Fibers

C. McCarthy, J. Li, A. Keim, G. Gierke, M. Nielsen, M. Frost, E. Bouta, H. Wang, R. Gilbert, J. Goldman;

Michigan Technological Univ., Houghton, MI.

686

Optimized Daptomycin Elution from Calcium Sulfate

K. Smith¹, W. Haggard¹, M. Smeltzer²;

¹Univ. of Memphis, Memphis, TN, ²Univ. of Arkansas for Med. Sci., Little Rock, AR.

687

In Vitro Evaluation of a Chitosan/ß-GP Gel for a Local Delivery of BMP-2 for Osteoblatic Differentiation

S. Kim, Y. Kang, Y. Yang;

Univ. of Texas Hlth.Sci. Ctr. at Houston, Houston, TX.

688

In Vitro Evaluation of a Chitosan/ß-GP Gel for a Local Delivery of BMP-2 for Osteoblatic Differentiation

S. Kim, Y. Yang, Y. Kang;

Univ. of Texas Hlth.Sci. Ctr. at Houston, Houston, TX.

689

Porous Poly(Caprolactone) Hollow Microspheres With Different Morphologies

T. S. Jang, E. J. Lee, H. E. Kim;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

690

Development of a Photo-Polymerizable Bone Graft Substitute as a Delivery System for Bone Morphogenetic Protein

A. J. McNally, K. Sly, S. Lin;

Exactech Inc., Gainesville, FL.

691

Microfibrous Non-woven Scaffolding for Liquid Drug Delivery

K. J. Garcia, J. T. Corbett, J. M. Olbrich, M. S. Taylor, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

692

Local Delivery of Proteins and Antibiotics from Elastin-based Scaffolds

S. S. Amruthwar, A. V. Janorkar;

Univ. of Mississippi Med. Ctr., Jackson, MS.

693

TCP Particles as a Sustained Release Carrier of Osteogenic Proteins

Y. Hou¹, J. Hu¹, H. Park², B. Wu³, M. Lee¹;

¹Sch. of Dentistry, Univ. of California, Los Angele, Los Angeles, CA, ²Dept. of Chemistry and Biochemistry, Univ. of California, Los Angele, Los Angeles, CA, ³Dept. of Bioengineering, Univ. of California, Los Angele, Los Angeles, CA.

694

Layer-By-Layer Assembled Oligodeoxynucleotide Sponge for Multi-Drug Delivery

J. Lee, Z. Poon, D. Bonner, J. Hong, P. Hammond;

Massachusetts Inst. of Technology, Cambrideg, MA.

695

Nanofibrous EGF Gene Delivery System Employing Mmps-Responsives Linkers

H. Kim, H. Yoo, J. Choi, Y. Son, S. Yoon, E. Jo;

Kangwon Natl. Univ., Chuncheon, KOREA, REPUBLIC OF.

696

Effect of Processing Temperature on Poly(lactic-co-glycolic acid) Scaffold Properties and Bioactivity of Insulin-like Growth Factor I

A. Clark, T. Milbrandt, Z. Hilt, D. Puleo;

Univ. of Kentucky, Lexington, KY.

697

In Vitro Degradation of Poly(DL/L-lactide-ε-caprolactone) Biomaterials

C. Davis, H. Bowman, P. Spencer;

SurModics Pharmaceuticals, Birmingham, AL.

Cancer Drug Delivery

698

Paclitaxel-Eluting Expansile Nanoparticles for the Treatment of Breast Cancer

K. V. Zubris¹, R. Liu², J. E. Wade², A. H. Colby¹, Y. L. Colson², M. W. Grinstaff¹;

¹Boston Univ., Boston, MA, ²Brigham and Women's Hosp., Boston, MA.

699

Mechanical Properties and Loading Techniques of Mucoadhesive Films for Treatment of Oral Dysplasia

S. K. Ramineni, D. Puleo, L. L. Cunningham, T. Dziubla;

Univ. of Kentucky, Lexington, KY.

700

Block Copolymer Nanoparticles for Gene Delivery in Tumor Model

D. Velluto, S. Thomas, M. A. Swartz, J. A. Hubbell;

EPFL, Lausanne, SWITZERLAND.

701

Femtosecond Laser-Assisted Optoporation for Drug and Gene Delivery into Single Mammalian Cells

P. Soman¹, W. Zhang², A. Umeda³, Z. Zhang³, S. Chen²;

¹Univ. of California, San Diego, La Jolla, CA, ²Univ. of California, San Diego, San Diego, CA, ³Univ. of Texas, Austin, Austin, TX.

702

Using DNA Nanostructures as Antisense Delivery Vehicles

J-W. Keum¹, J-H. Ahn², H. Bermudez¹;

¹Univ. of Massachusetts, Amherst, MA, ²MIT, Cambridge, MA.

703

Inhibition of Non-Small Cell Lung Carcinoma (NSCLC) Tumor Growth by Arginine-Albumin Microspheres

H-Y. Lee, H-Y. Lee;

Univ. of Florida, Gainesville, FL.

704

New Process for the Exclusive γ-Conjugation of Folic Acid for Targeted Drug Delivery

J. E. Puskas, K. Seo, L. Dos Santos;

The Univ. of Akron, Akron, OH.

705

Injectable Absorbable Liquid Gel-Forming Systems for Localized Delivery of Therapeutic Agents

J. M. Olbrich¹, J. T. Corbett¹, K. J. L. Burg², W. S. W. Shalaby¹, S. W. Shalaby¹;

¹Poly-Med, Inc., Anderson, SC, ²Clemson Univ., Clemson, SC.

706

Monocytes Hybridized with PAMAM Dendrimer-Doxorubicin Conjugates for Anticancer Drug Delivery

C. A. Holden, W. Yeudall, H. Yang;

Virginia Commonwealth Univ., Richmond, VA.

707

In Vivo Tumor Toxicity of Doxorubicin Encapsulated in Peptide-Assembled Polylactide Nanoparticles

X. He, X. Yang, E. Jabbari;

Univ. of South Carolina, Columbia, SC.

708

Release and Uptake of Pluronic from In Situ Forming PLGA Implants

A. Carlson, T. Krupka, L. Solorio, A. A. Exner;

Case Western Reserve Univ., Cleveland, OH.

709

A Novel Micellar-Like Polymeric Nanoparticle for Paclitaxel Delivery: In Vitro and In Vivo Evaluation

L. Zhang, G. Ma, Y. He, C. Song;

Inst. of BioMed. Engineering, PUMC & CAMS, Tianjin, CHINA.

710

Autocatalytic Drug Delivery Vehicles

N. Murthy;

Georgia Tech, Atlanta, GA.

711

In vitro and in vivo siRNA Delivery Using Modified Hyperbranched PEI

X. Chen;

Changchun Inst. of Applied Chemistry, Changchun, CHINA.

712

Development and Characterization of Cellular Microarrays For Screening Signaling Pathway Inhibitors

M. R. Carstens, A. Acharya, E. Huang, B. Keselowsky;

Univ. of Florida, Gainesville, FL.

713

Mixed Micelles Composed of PEG-lipids and Cytotoxic Peptide Amphiphiles for Cancer Therapy

M. J. Black¹, M. V. Tirrell²;

¹Univ. of California, Santa Barbara, Santa Barbara, CA, ²Univ. of California, Berkeley, Berkeley, CA.

714

Photosensitizer Encapsulated Hyaluronic Acid Nanoparticles for Photodynamic Therapy of Tumor

H. Yoon¹, K. Choi¹, H. Koo², K. Kim², I. Kwon², J. Park³;

¹Dept. of Life and Nanopharmaceutical Sci., Kyung Hee Univ., Seoul, Korea, Republic of. BioMed. Res. Ctr., Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ²BioMed. Res. Ctr., Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ³Dept. of Life and Nanopharmaceutical Sci., Kyung Hee Univ., Seoul, Korea, Republic of. Dept. of Chemical Engineering, Coll. of Engineering, Kyung Hee Univ., Gyeonggi-do, KOREA, REPUBLIC OF.

715

Synthesis and Characterization of PEG-Iron Oxide Core-Shell Nanoparticles for Cancer Therapy

R. J. Wydra, A. M. Kruse, Y. Bae, K. W. Anderson, J. Z. Hilt;

Univ. of Kentucky, Lexington, KY.

716

The Efficacy of Magnetic Target Drug Delivery to Treat Skin Cancer

H. E. Misak¹, F. Abedin¹, P. H. Wooley², R. Asmatulu¹, S-Y. Yang²;

¹Wichita State Univ., Wichita, KS, ²Via Christi Regional Med. Ctr., Wichita, KS.

717

Formation and Characterization of Drug Encapsulated Polymeric Microspheres for Localized Brain Tumor Therapy

J. Floyd, A. Galperin, R. Ramakrishna, R. Rostomily, B. D. Ratner;

Univ. of Washington, Seattle, WA.

718

Material Independent Surface Chemistry for Gold Shell Formation Inspired by Plant Flavonoids

H. Lee;

MIT, Cambridge, MA.

719

Biotinylated PLGA Nanoparticles as Versatile Targeting Vehicles for Anti-Cancer Drug Delivery

O. Donaldson, L. Bell, E. Wagner, N. Comolli;

Villanova Univ., Villanova, PA.

Ceramics in Drug Delivery

720

Polymer Coated Mesoporous Silica Controlled Release Nanoparticles for Macromolecules

S. Bhattacharyya, H. Wang, P. Ducheyne;

Univ. of Pennsylvania, 210 S. 33rd Street, PA.

721

Osteoblast-like MG-63 Cells Behavior on Poly-Caprolactone/Wollastonite Nanocomposites Surface

J. Podporska;

Dublin City Univ., Dublin, IRELAND.

722

Drug Delivery from Calcium Sulfate/Hydrogel Space-Making Composites

B. R. Orellana, M. V. Thomas, J. Z. Hilt, D. A. Puleo;

Univ. of Kentucky, Lexington, KY.

723

Calcium Phosphates in Drug Delivery: Adsorption and Release Kinetics of Lovastatin

S. Bose;

Washington State Univ., Pullman, WA.

724

Gene Transfection Using PVA/HAp/DNA Nanoparticles Prepared by High Hydrostatic Pressurization

T. Kimura¹, K. Nam¹, T. Furuzono², M. Okada², A. Kishida¹;

¹Tokyo Med. and Dental Univ., Tokyo, JAPAN, ²Natl. Cardiovascular Ctr. Res. Inst., Osaka, JAPAN.

725

Controlling Silica-induced Oxidative Stress to Facilitate Therapeutic Applications of Engineered Silica

J. Ambati¹, A. Lopez², D. Cochran¹, P. Wattamwar¹, K. Bean³, T. Dziubla¹, S. Rankin¹;

¹Univ. of Kentucky, Lexington, KY, ²Univ. of Arkansas, Fayetteville, AR, ³Tuskegee Univ., Tuskegee, AR.

Ceramics in Orthopaedic and Dental Applications

726

Bioactive Glass Scaffold with Oriented Porous Structure for the Repair of Load Bearing Bones

X. Liu, M. N. Rahaman;

Missouri Univ. of Sci. and Technology, Rolla, MO.

727

In vitro Characterization of Lithium-Doped Tricalcium Phosphate for Bone Graft

S. Bose;

Washington State Univ., Pullman, WA.

728

Increasing the Potential of Bioactive Glass as a Scaffold for Bone Tissue Engineering with Synthetic ECM

M. Ammar, C. Przybylowski, S. S. Jedlicka;

Lehigh Univ., Bethlehem, PA.

729

Hydroxyapatite Platelets in Physiological Environment

A. Slepko, A. A. Demkov;

The Univ. of Texas at Austin, Austin, TX.

730

Effect of Silica and Titania Doping on Calcium Phosphate-Based Glass Properties for Bone Tissue Engineering

M. Shah Mohammadi¹, N. Muja¹, C. Stähli¹, M. N. Bureau², S. N. Nazhat¹;

¹McGill Univ., Montreal, QC, CANADA, ²Industrial Materials Inst., Natl. Res. Council Canada, Boucherville, QC, CANADA.

731

Fiber Reinforced Calcium Silicate Phosphate Bone Cements

A. Goudarzi, T. Troczynski, N. D. Ruse;

Univ. of British Columbia, Vancouver, BC, CANADA.

732

Practical Considerations in Accurate Determination of Ca/P Ratios of Calcium Phosphate Materials

M. A. Ross, W. Tong;

DePuy Orthopaedics Inc., Warsaw, IN.

733

Bioactive Injectable Nanotube/Nano-HA/Phema Composites for Orthopedic Applications

L. Sun;

Brown Univ., Providence, RI.

734

The Effect of Sio₂ and Zno Doping On the Mechanical and Biological Properties of Β-TCP Scaffolds Fabricated Using Three-Dimensional (3-D) Printing

S. Bose;

Washington State Univ., Pullman, WA.

735

Preparation and Characterization of Hydroxyapatite Doped with La3+

Z. Xia, E. Johnson, M. Wei;

Univ. of Connecticut, Storrs, CT.

736

Hydrating Calcium Phosphate/ Demineralized Bone Matrix Graft Material with Blood, Bone Marrow, and Antibiotics

A. D. Rosenberg, N. Camacho, J. Chang;

ETEX Corp., Cambridge, MA.

737

Preparation of Porous Calcium Phosphate Cement from a-TCP Balls

K. Ishikawa¹, K. Turu¹, T. Kien¹, M. Maruta¹, S. Matsuya²;

¹Kyushu Univ., Fukuoka, JAPAN, ²Fukuoka Dental Coll., Fukuoka, JAPAN.

738

Effect of L-Arginine, and L-Glutamic Acid in Solution on the Crystallization of Hydroxyapatite

M. Tavafoghi Jahromi, M. Cerruti;

McGill Univ., Montreal, QC, CANADA.

739

Silver Doped Hydroxylapatite Plasma Sprayed Coatings - Antimicrobial Properties and Cytotoxic Effect on Human Osteoblasts

J. Podporska;

Dublin City Univ., Dublin, IRELAND.

Orthopaedic Alternative Bearing Surfaces: Laboratory Findings and Clinical Actualities

740

Highly Impact Resistant Surface Crosslinked UHMWPE for Total Joint Implants

E. Oral, O. K. Muratoglu;

Massachusetts Gen. Hosp., Boston, MA.

741

The Growth and Characteristics of a Micro-textured Surface on Ti6Al4V

S. J. L. Sullivan, L. D. T. Topoleski;

Univ. of Maryland, Baltimore County, Baltimore, MD.

742

Effect of Head Size and Liner Thickness on the Wear of Crosslinked, Thermally-Remelted UHMWPE

C. Laukhuf, P. Liao, C. Hardaker;

DePuy Orthopaedics, Warsaw, IN.

743

A New Highly-Radiopaque Bone Cement with Built-in Iodine, and its Potential Utility in Vertebroplasty.

A. Pepiol¹, C. Vinas¹, M. L. Knetsch², K. Saralidze², L. Koole²;

¹Materials Res. Inst. of Barcelona, Barcelona, SPAIN, ²Maastricht Univ., Maastricht, NETHERLANDS.

744

A Pseudoelastic Approach to Sustain Compression in Bone Fractures and Fusions in Response to Bone Resorption

C. M. Yakacki¹, K. Gall², R. Patel², D. Dirschl³, D. Pacaccio⁴;

¹MedShape Solutions, Atlanta, GA, ²The Georgia Inst. of Technology, Atlanta, GA, ³Univ. of North Carolina, Chapel Hill, NC, ⁴Advanced Foot and Ankle Surgeons, Yorkville, IL.

745

The Effect of ASTM F-2003 Accelerated Aging of UHMWPE on Specimen Weight Change

C. E. Golightly, E. E. Sloan, E. M. Lucas, J. D. DesJardins;

Clemson Univ., Clemson, SC.

746

Comparison Between Gravimetric Wear and Wear Scar Size from Tibial Inserts Tested in a Knee Simulator

M. E. Roy¹, L. A. Whiteside², B. J. Katerberg³, D. J. Schnettgoecke³;

¹Missouri Bone & Joint Res. Fndn., St. Louis, MO, ²Missouri Bone & Joint Res. Fndn.; Signal Med. Corp., St. Louis, MO, ³Signal Med. Corp., St. Louis, MO.

747

Effect of Roughened Counterpart on Behaviors of Vitamin E Infused Ultra-High Molecular Weight Polyethylene

Q. Wang¹, J. Wu¹, I. Khan²;

¹Durham Univ., Durham, UNITED KINGDOM, ²Biomet UK Ltd, Swindon, UNITED KINGDOM.

Scaffold Assisted Bone Defect Repair / Regeneration

748

3D Polymer Reinforced Calcium Phosphate Cement Scaffolds for Bone Tissue Engineering

D. L. Alge¹, S. Harbin¹, W. S. Goebel², J. Bennett³, T. Treasure³, T-M. G. Chu³;

¹Purdue Univ., West Lafayette, IN, ²Indiana Univ. Sch. of Med., Indianapolis, IN, ³Indiana Univ. Sch. of Dentistry, Indianapolis, IN.

749

Modified Calcium Phosphate Biomaterials as Human Mesenchymal Stem Cell Delivery Vehicles for Bone Repair

S-H. Park¹, D. L. Kaplan², J. Chang¹;

¹ETEX Corp., Cambridge, MA, ²Tufts Univ., Medford, MA.

750

Shape Memory and Porosity Characteristics of a Novel Orthopaedic Scaffold

C. G. Gamboa, A. P. Govil;

N. I. Thompson; Advanced Biologics LLC, Ladera Ranch, CA.

751

Response Behaviors Study Of Human Bone Marrow-Derived Mesenchymal Stem Cells and Endothelial Cells to Calcium Phosphate Scaffold

Y. Kang¹, S. Kim¹, J. Donnelly², N. Sadr², Y-C. Chen², H. Bae², A. Khademhosseini², Y. Yang¹;

¹the Univ. of Texas Hlth.Sci. Ctr. at Houston, Houston, TX, ²Harvard-MIT Div. of Hlth.Sci. and Technology, Cambridge, MA.

752

A Newly Developed Biodegradable Injectable Polymer-Metallic Hybrid Material

H. Wong¹, K. Yeung¹, P. Chu², K. Luk¹, K. Cheung¹;

¹The Univ. of Hong Kong, Hong Kong, HONG KONG, ²City Univ. of Hong Kong, Hong Kong, HONG KONG.

753

Biomineralized Highly Aligned Nanofiber Array Based Building Unit for Bone Regeneration

E. M. Katsanevakis, V. Beachley, X. Wen, N. Zhang;

Clemson Univ., Charleston, SC.

754

Silicon Substituted Calcium Phosphate Biomaterials - The Effect of Strut Porosity on Osteoinduction

M. J. Coathup¹, O. Chan¹, K. A. Hing², T. Buckland³, C. Campion³, G. W. Blunn¹;

¹Univ. Coll. London, Stanmore, Middlesex, UNITED KINGDOM, ²Queen Mary Univ. London, London, UNITED KINGDOM, ³ApaTech Ltd, Elstree, UNITED KINGDOM.

755

Novel Totally Biodegradable Biomimetic Scaffolds for Bone Regeneration and Repair

M. Bergenstock, N. Wang, W. Lau, Q. Liu;

3D Biotek, North Brunswick, NJ.

756

Dense Collagen-Nanosized Bioactive Glass Hybrid as Rapid Implantable Scaffold for Bone Tissue Engineering

B. Marelli¹, C. E. Ghezzi¹, J. E. Barralet¹, A. R. Boccaccini², S. N. Nazhat¹;

¹McGill Univ., Montreal, QC, CANADA, ²Univ. of Erlangen-Nürnberg, Erlangen, GERMANY.

757

Effects of SC-CO₂ Sterilization and Storage on Osteoinductivity of DBM

Q-Q. Qiu, J. Connor;

LifeCell Corp., Branchburg, NJ.

758

Microcracks Enhance OB Maturation In Vitro

Y. Shu, M. J. Baumann, E. D. Case, S. Meyer, M. Buczkowski, K. Tyler, R. Irwin, L. R. McCabe;

Michigan State Univ., East Lansing, MI.

759

Highly Aligned Porous Alumina Ceramics by Extruding Unidirectionally Frozen Alumina/Camphene Body

Y-W. Moon¹, K-H. Shin¹, J-H. Sung¹, Y-H. Koh¹, W-y. Choi², Y. Jin², H-E. Kim²;

¹Korea Univ., Seoul, KOREA, REPUBLIC OF, ²Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

760

Novel Orthopaedic Implant with Antimicrobial Properties and Reverse Phase Medium

C. G. Gamboa, A. P. Govil, N. I. Thompson;

Advanced Biologics LLC, Ladera Ranch, CA.

761

Mechanical Properties and Bioactivity of PEEK-OPTIMA^®/Hydroxyapatite Compounds

M. Brady¹, A. H. C. Poulsson², J. Wilson¹, D. Eglin², G. Richards², M. Jarman-Smith¹;

¹Invibio Ltd, Thornton-Cleveleys, UNITED KINGDOM, ²AO Res. Inst., Davos, SWITZERLAND.

762

Bioactive Glass-Collagen Scaffolds for Treating Infected Bone

S. Cooper¹, M. Goude¹, K. Lim¹, M. So², A. B. Brennan¹;

¹Univ. of Florida, Gainesville, FL, ²Vanderbilt Univ., Nashville , TN.

763

Ovalbumin-Based Scaffolds reinforced with Cellulose Nanocrystals for Bone Tissue Regeneration

B. P. Glaesemann, A. Wittington, M. Roman;

Viriginia Polytechnic and State Univ., Blacksburg, VA.

764

Exposed Hydroxyapatite Particles on the Surface of Photo-crosslinked Nanocomposites and Promoted MC3T3 Cell Function

L. Cai, S. Wang;

The Univ. of Tennessee Knoxville, Knoxville, TN.

765

Effect of Calcium Coating on Tyrosine-Derived Polycarbonate Scaffold Architecture

O. Ortiz¹, M. H. R. Magno¹, R. Z. LeGeros², A. Darr¹, J. Kohn¹;

¹Rutgers, The State Univ. of New Jersey, Piscataway, NJ, ²New York Univ., New York, NY.

766

Mineralized Tissue Formation by Human Osteoblasts in Contact with Biodegradable Polymers

K. F. Bombonato-Prado¹, L. S. Pinto¹, A. L. Rosa¹, V. D. Jahno², R. R. Fernandes¹;

¹Univ. of São Paulo, Ribeirão Preto, BRAZIL, ²Catholic Univ. of Rio Grande do Sul, Porto Alegre, BRAZIL.

767

Highly Porous Bioresorbable Scaffolds with Protein Controlled Release for Tissue Regeneration Applications

O. Grinberg, I. Binderman, J. J. Elsner, M. Zilberman;

Tel Aviv Univ., Ramat Aviv, ISRAEL.

Characterization of and Cellular Response to Orthopaedic Wear Debris

768

Systemic Homing of Osteoprogenitor Cells to Continuously Infused UHMWPE Particles In Vivo

P-G. Ren, Z. Huang, K. Fritton, T. Ma, S. Biswal, R. L. Smith, S. B. Goodman;

Stanford Univ., Stanford, CA.

769

Primary Human Macrophage Responses to PEEK-OPTIMA® and UHMWPE Particulate Implant Debris

N. J. Hallab¹, A. Kinbrum², M. Brady²;

¹Rush Univ. Med. Ctr., Chicago, IL, ²Invibio Biomaterial Solutions, Thornton-Cleveleys, UNITED KINGDOM.

770

Characterization and Quantification of Wear-debris from Periprosthetic Tissues from Total Hip Patients

M. K. Musib, V. Rasquinha, S. Saha;

SUNY Downstate Med Ctr., Brooklyn, NY.

771

Oncogenesis in Arthroplasty

C. J. Lavernia;

Orthopaedic Inst. at Mercy, Miami, FL.

Dental Materials

773

Response of Osteoblast-Like Cells to Poling Titania Coating

A. Nagai¹, Y. Yamazaki¹, C. Ma¹, Y. Tsutsumi¹, T. Hanawa¹, T. Toyama², K. Yamashita¹;

¹Tokyo Med. & Dental Univ., Tokyo, JAPAN, ²Nihon Univ., Tokyo, JAPAN.

774

Integrative Design of a Poly(ethylene glycol)-Poly(propylene glycol)-Alginate Hydrogel for Three Dimensional Biomineralization

C. Cha, H. Kong;

Univ. of Illinois, Urbana, IL.

775

A Trilayer Fibrous Composite Scaffold with nHA for Periodontal Regeneration

V. Thomas¹, J. P. Ball², M. C. Bottino¹, Y. K. Vohra¹;

¹Univ. of Alabama at Birmingham, Birmingham, AL, ²Univ. of Florida, Gainesville, FL.

776

Synthesis and Characterization of Nanostructured Dental Polymers through Phase Dispersion Control

Q. Ye, J. Park, A. Misra, R. Parthasarathy, V. Singh, P. Spencer;

Univ. of Kansas, Lawrence, KS.

777

Enzyme Immobilization Enhances GBR-Membrane Performance

J. van den Beucken, D. Oortgiesen, A. Plachokova, G. Meijer, J. Jansen;

Radboud Univ. Nijmegen Med. Ctr., Nijmegen, NETHERLANDS.

778

Correlation Between Citotoxity Of Self-Etching Resin Cements On The Cell Cycle Of Fibroblasts And Degree Of Conversion

K. I. R. Teixeira, Jr., L. F. d. Morgan, Jr., R. d. Albuquerque, Sr., M. E. Cortés, Sr., L. T. A. Poletto, Sr.;

UFMG, Belo Horizonte, BRAZIL.

779

Preparation of a PQAS-containing Dental GIC Cement for Improved Antibacterial Function

Y. Weng, D. Xie;

Indiana Univ. Purdue Univ. Indianapolis, Indianapolis, IN.

780

Methacrylate Derivatives of Bile Acids for Use as Monomers for Dental Resins

M. A. Gauthier, S. Lerouge, D. Fortin, J. X. Zhu;

Univ. of Montreal, Montreal, QC, CANADA.

781

Correlation Between Osseointegration And Implant Surfaces - Roughness And Coating

M. Adam¹, C. Ganz¹, W. Xu¹, H. R. Sarajian², B. Frerich², T. Gerber¹;

¹Inst. of Physics, Univ. of Rostock, Rostock, GERMANY, ²Dept. of Oral & Maxillofacial Plastic Surgery, Univ. of Rostock, Rostock, GERMANY.

782

Plasma Treatment of Dentin Surface for Enhanced Wettability

A. C. Ritts¹, A. Blumhagen¹, Q. Yu¹, H. Li¹, UMKC, X. Yao², Y. Wang², C. Xu², L. Hong³, M. Chen⁴;

¹Univ. of Missouri, Columbia, MO, ²Univ. of Missouri-Kansas City, Kansas City, MO, ³Univ. of Tennessee, Memphis, TN, ⁴Nanova Inc, Columbia, MO.

Conducting Polymers as Biomaterials

783

Multiple Electrical Stimulation Through Conductive PLLA/Ppy/Heprin Scaffold Promotes In Vitro Bone Regeneration

M. Rouabhia;

Laval Univ., Quebec, QC, CANADA.

784

Carbon Nanotube Doped Poly(3,4-Ethylenedioxythiophene) for Chronic Neural Stimulation

X. Luo¹, C. L. Weaver¹, D. D. Zhou², R. Greenberg², X. T. Cui¹;

¹Univ. of Pittsburgh, Pittsburgh, PA, ²Second Sight Med. Products, Inc., Sylmar, CA.

785

Graphene Nanocomposites for Neural Tissue Applications

W. He, E. Parrish;

Univ. of Tennessee, Knoxville, TN.

786

Amperometric Glucose Biosensor Based On Conducting Polymer Nanotubes

M. Abidian;

Pennsylvania State Univ., University Park, PA.

Tribocorrosion of Metallic Biomaterials

787

Effect of Proteins and Normal Load on the Tribocorrosion Behavior of Hip Joint Implant Material (CoCrMo Alloy)

M. J. C. Runa¹, M. M. T. Mathew², C. Nagelli², M. Laurent², J. Jacobs², M. Wimmer², L. Rocha¹;

¹Univ. of Minho, Guimarães, PORTUGAL, ²Rush Univ. Med. Ctr., Chicago, IL.

788

Toxicological Risk of Magnesium Alloys as Implant Materials - Theoretical and Experimental Assessment

W. Ip, C. Yuen;

The Univ. of Hong Kong, Hong Kong SAR, HONG KONG.

789

Investigation of the Tribocorrosion Between Polyethylene and Cobalt-chromium

J. Hesketh;

Univ. of Leeds, Leeds, UNITED KINGDOM.

790

Iron-Substitution in Hydroxyapatite Using a Simple Ion Exchange Soaking Procedure

E. Kramer, M. Staruch, M. Jain, M. Wei;

Univ. of Connecticut, Storrs, CT.

791

Tribocorrosion and Corrosion Resistance in Artificial Saliva of Tin/Nc-Tin/A-Si3N4 Coating Deposited By Magnetron Sputtering

J. J. GARCIA¹, M. Flores², O. JIMENEZ²;

¹Universidad Panamericana, Zapopan, MEXICO, ²Universidad De Guadalajara, Zapopan, MEXICO.

Chemoselective Chemistry for Biomaterials

792

Chemoselective Chemistry of Catechol for HA hydrogels and Conjugation of Biological Molecules

M. Lee, H. Lee;

KAIST, Daejeon, KOREA, REPUBLIC OF.

793

Covalent Layer by Layer (CLbL) Assembly of Hydrogel Coatings via Chemoselective Staudinger Ligation

H. R. Rengifo, K. M. Gattás-Asfura1, J. A. Giraldo, C. L. Stabler;

Univ. of Miami Miller Sch. of Med., Miami, FL.

Mechanical Characterization of Biomaterials

794

Effect of X-Ray Irradiation on Porcine and Murine Cartilage Modulus

A. Lindburg, S. A. Bielby, J. S. Willey, J. D. DesJardins, D. M. Dean;

Clemson Univ., Clemson, SC.

795

Mechanical Properties of Processed Chitosan Fibers for Use in Scaffold Reinforcement

O. Blowytsky¹, M. Z. Albanna¹, H. L. Walters, III², H. W. T. Matthew¹;

¹Wayne State Univ., Detroit, MI, ²Children's Hosp. of Michigan, Detroit, MI.

796

Thin Films Prepared from Novel Absorbable Polymers for Use as Compliant Wrap

K. D. Gray, Jr., R. T. Pace, M. S. Taylor, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

797

Deterioration of Compressive Properties of Bone Cement due to Release of Multiple Antibiotics over Extended Time Periods

M. K. Musib, K. Chakote, W. Hayes, V. Rasquinha, S. Saha;

SUNY Downstate Med Ctr., Brooklyn, NY.

798

Effect of Ionizing Radiation on the Modulus and Residual Strains in Bone

A. Singhal¹, A. C. Deymier-Black¹, J. D. Almer², D. C. Dunand¹;

¹Northwestern Univ., Evanston, IL, ²Argonne Natl. Lab., Argonne, IL.

799

Development of Surrogate Annulus for Nucleus Replacement Devices- A Load Sharing Study

V. Singh, B. R. Morrow, C. G. Ogden, K. M. Sitton;

Medtronic, Inc., Memphis, TN.

800

Strain Characterization and Modeling of Bone-Implant System

F. Yuan¹, A. Singhal¹, J. D. Almer², L-P. Lefebvre², D. C. Dunand¹, L. C. Brinson¹;

¹Northwestern Univ., Evanston, IL, ²Argonne Natl. Lab., Argonne, IL.

801

Carbon-Fiber Reinforced PEEK for Cervical Disc Arthroplasty

G. D. G. Langohr, H. Gawel, N. Maheshwari, J. B. Medley;

Univ. of Waterloo, Waterloo, ON, CANADA.

802

Characterization of Cell-Seeded PEGDA Hydrogels Adapted for Tissue Engineered Heart Valves

C. A. Durst, M. P. Cuchiara, E. G. Mansfield, J. L. West, K. J. Grande-Allen;

Rice Univ., Houston, TX.

803

Quantifying Deformation and Recovery of Polyethylene in Total Knee Replacement

A. M. Metcalfe¹, J. L. Tikka¹, M. A. Strickland², M. R. Dressler¹;

¹DePuy Orthopaedics Inc, Warsaw, IN, ²Bioengineering Sci. Res. Group, Univ. of Southampton, Southampton, UNITED KINGDOM.

804

Micromechanical characterization of Inter- and Intra-Lamellar Annulus Fibrosus Specimens

J. L. Isaacs¹, E. Vresilovic², M. Marcolongo¹;

¹Drexel Univ., Philadelphia, PA, ²Pennsylvania State Univ., Dept. of Orthopedic Surgery, Harrisburg, PA.

805

The Influence of Machining on Micro-hardness Properties of CoCrMo Alloys

O. Vesnovsky¹, B. Farrokh², L. D. T. Topoleski², L. W. Grossman¹;

¹FDA, Silver Spring, MD, ²UMBC, Baltimore, MD.

806

Tissue-on-Tissue Lubrication by Natural and Xerostomic Saliva and Saliva Substitutes

R. Ganesh, M. N. Hatton, R. E. Baier, A. E. Meyer;

Univ. at Buffalo, Buffalo, NY.

807

Constitutive Model for Stress on Nickel - Titanium Shape Memory Alloy Considering an Austenite - Twinned Martensite - Detwinned Martensite Phase Transformation Approach

M. I. Varela-Jimenez, M. Bueno, J. A. Cortes;

Tecnologico de Monterrey, Monterrey, MEXICO.

808

Influence of Fluid Flow on Porous Scaffold Structural Deformation

J. Podichetty, S. Madihally;

Oklahoma State Univ., Stillwater, OK.

809

Biomechanics and Enzymatic Degradation of Two Acellular Dermal Matrices

J. A. Faleris, J. D. Michaelson, R. M. C. Hernandez, R. Prado, S. T. Moore, R. Cobb;

RTI Biologics, Alachua, FL.

810

Advanced Nanoindentation of Viscoelastic Properties in Soft Biomaterials

N. Randall, B. Zhou;

CSM Instruments, Needham, MA.

811

A Novel High Strength and High Porosity Titanium Scaffold

J. L. Krevolin, J. Liu, K. Patel, R. Dahl;

Bio2 Technologies, Woburn, MA.

Biocompatibility and Surface Chemistry: Where the Rubber Meets the Road

812

Preparation, Characterization, and in vitro Evaluation of Mineral/Osteogenic Growth Peptide Composite Grown on Calcium Phosphate Coated CP Titanium

C. Chen¹, I-S. Lee¹, S-M. Zhang², H-C. Yang³, S-H. Choi⁴, S-M. Chung⁵; ¹

Atomic-scale Surface Sci. Res. Ctr., Yonsei Univ., Seoul, KOREA, REPUBLIC OF, ²Advanced Biomaterials and Tissue Engineering Ctr., HUST, Wuhan, CHINA, ³Dept. of Dental Biomaterials Sci., Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF, ⁴Dept. of Periodontology, Yonsei Univ., Seoul, KOREA, REPUBLIC OF, ⁵Implatium Implant Inst., Seoul, KOREA, REPUBLIC OF.

813

Stable Oxygen Plasma Surface Modification of PEEK to Improve Osteoblast Cytocompatibility

A. Poulsson, R. Richards;

AO Res. Inst., Davos Platz, SWITZERLAND.

814

Detailed Characterization of Sodium Hyaluronate using Aqueous Size Exclusion Chromatography with Advanced Detection

P. Harmon, P. Maziarz, M. Liu;

Bausch and Lomb, Rochester, NY.

815

Assessment of Protein-Biomaterial Surface Interaction by Streaming Potential Measurement

T. Luxbacher;

Anton Paar GmbH, Graz, AUSTRIA.

816

Cytocompatible Polymer Surface with Photocleavable Groups for Regulating the Single Cell Attachment/Detachment

B. Byambaa, T. Konno, K. Ishihara;

The Univ. of Tokyo, Tokyo, JAPAN.

817

Immobilization of Polyethylene Glycol-Corn Trypsin Inhibitor on Polyurethane for Inhibition of Contact Factor Activation upon Blood Contact

S. Alibeik, S. Zhu, J. Yau, J. Weitz, J. Brash;

McMaster Univ., Hamilton, ON, CANADA.

818

Surface Modification Of 3C-Sic (001) Via Organic Functionalization

A. Oliveros¹, S. J. Schoell², C. Frewin¹, I. D. Sharp², S. E. Saddow¹;

¹Univ. of South Florida, Tampa, FL, ²Walter Schottky Inst., Garching, GERMANY.

819

Platelet Response to PEG-Modified Surface With Different Molecular Architecture

S. Kakinoi¹, L. Ye², Y. Inoue³, K. Ishihara³, N. Yui⁴, T. Yamaoka¹;

¹Natl. Cerebral and Cardiovascular Ctr. Res. Inst., Osaka, JAPAN, ²Japan Advanced Inst. of Sci. and Technology, Ishikawa, JAPAN, ³The Univ. of Tokyo, Tokyo, JAPAN, ⁴Advanced Inst. of Sci. and Technology, Ishikawa, JAPAN.

820

The Cell Biocompatibility of Human Pulpal Fibroblasts After Photodynamic Therapy

I. M. A. Diniz, K. I. Teixeira, P. V. Araújo, L. A. Poletto, M. Cortés;

Federal Univ. of Minas Gerais, Belo Horizonte, BRAZIL.

821

Heat Generation Characteristics of the Annealed Duplex Stainless Steel Thermo-Rod for Hyperthermia

Y. Kim¹, H-w. Choo¹, E-M. Hwang², S-m. Choi³;

¹INJE Univ., Kimhae City, KOREA, REPUBLIC OF, ²Koswire Ltd, Yangsan, KOREA, REPUBLIC OF, ³Catholic Univ. of Pusan, Busan, KOREA, REPUBLIC OF.

Surface Modification for Sensors and Diagnostics

822

Animating Optical Materials for a Sensor Device

P-Y. Chung, T-H. Lin, G. Schulz, C. Batich, P. Jiang;

Univ. of Florida, Gainesville, FL.

823

Combined Micro-Contact Printing and Microfluidic Patterning of Biomarkers in a microfluidic device

T. F. Didar, M. Tabrizian, A. M. Foudeh, J. Daoud;

McGill Univ., Montreal, QC, CANADA.

824

Surface Modification with Hydrophobin Proteins

Q. Ren, V. K. Morris, A. H. Kwan, M. Sunde;

Univ. of Sydney, Sydney, AUSTRALIA.

825

Bromocresol Green pH Sensor in the Presence of Nitric Oxide

M. Nielsen, M. C. Frost;

Michigan Technological Univ., Houghton, MI.

Thin-film Surface Modification of Biomaterials - Applications in Medical Devices

826

Simple and Effective Non-Thrombogenic Surface Modifications using Macro Zwitterionic Surface Modifiers for Metallic Blood Contacting Devices

S-H. Ye, C. A. Johnson, Jr., J. R. Woolley, V. Shankarraman, W. R. Wagner;

McGowan Inst. for Regenerative Med., Univ. of Pittsburgh, Pittsburgh, PA.

827

Tissue Plasminogen Activator-Containing Polyurethane Surfaces for Fibrinolytic Activity

Z. Wu¹, H. Chen¹, J. L. Brash²;

¹Coll. of Chemistry,Soochow Univ., Suzhou, CHINA, ²Sch. of BioMed. Engineering, McMaster Univ., Hamilton, ON, CANADA.

828

Enhanced Adhesion of Polymer Coating on Stainless Steel Surface by Direct Ring-Opening Polymerization of L-Lactide

S. Cho¹, J. Choi¹, K. Park¹, D. Chung², D. Han¹;

¹Korea Inst. of Sci. and Technology, Seoul, KOREA, REPUBLIC OF, ²Sungkyunkwan Univ., Suwon, KOREA, REPUBLIC OF.

829

Hydroxyapatite Coating on Magnesium in Aqueous Solution for Biomedical Applications

S-M. Kim, J-H. Jo, H-E. Kim;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

830

Biocompatible Surface Generation on Poly(ether ether ketone) by Self-initiated Photoinduced Graft Polymerization

T. Tateishi¹, M. Kyomoto¹, T. Yamaoka², K. Ishihara¹;

¹Dept. of materials engineering, The Univ. of tokyo, Tokyo, JAPAN, ²Natl. Cerebral And Cardiovascular Center Research Inst., Osaka, JAPAN.

831

Functionalized Alginate Hydrogel Coatings for Endothelial Progenitor Cell Capture from Whole Blood

A. Hatch;

Northeastern Univ., Boston, MA.

832

Surface Treatments for Orthopaedic Implants which Prevent Bacteria Growth and Support Cell Proliferation

J. D. Jarrell, Sr.¹, P. A. Tran², C. Baker³, J. R. Morgan³, R. A. Hayda², C. T. Born²;

¹BioIntraface, Inc, Riverside, RI, ²Rhode Island Hosp., Providence, RI, ³Brown Univ., Providence, RI.

833

Surface Modification of Equiatomic Nitinol Alloy to Reduce Ni Ion Release

A. Bandyopadhyay;

Washington State Univ., Pullman, WA.

834

Flexible HA Coating On Magnesium for Orthopedic Implant Applications

J-H. Jo, H-E. Kim;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

835

Nanometer-Thick Collagen/Calcium Phosphate Coatings with Improved Mechanical and Biological Performance

L. T. de Jonge, S. C. G. Leeuwenburgh, J. J. J. van den Beucken, J. G. C. Wolke, J. A. Jansen;

Radboud Univ. Nijmegen Med. Ctr., Nijmegen, NETHERLANDS.

836

Phase Separated Polymer Blend Thin Film Scaffolds for Wound Healing Application

C. Zhang, J. Marszalek, Z. He, A. Karim;

The Univ. of Akron, Akron, OH.

Polymeric Biomaterials - Synthesis, Characterization, Processing and Fabrication for Biomedical Applications

837

Efficient, Greener Synthesis of Reducible Disulfide Polymers and Disulfide Crosslinked Networks

E. Q. Rosenthal, J. E. Puskas;

The Univ. of Akron, Akron, OH.

838

Biocompatibility and Thermal Properties of Absorbable Thermoplastic Polyurethanes

R. S. Bezwada, N. Srivastava;

Bezwada BioMed., LLC, Hillsborough, NJ.

839

Characterization of Novel Injectable Click-Hydrogel Scaffold for the Treatment of Re-Synostosis

C. Hermann¹, S. Wilson¹, X. Ning¹, R. Olivares-Navarrete¹, R. Guldberg¹, N. Murthy¹, J. Williams², B. Boyan¹, Z. Schwartz¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Children's Hlth.care of Atlanta, Atlanta, GA.

840

Controlling The In Vivo Degradation Rate of Poly(ethylene carbonate) Through Crosslinking

L. Cornacchione, B. G. Amsden;

Queen's Univ., Kingston, ON, CANADA.

841

Coefficient Of Friction of Polyvinyl (Alcohol) Based Hydrogels Against Swine Articular Cartilage

H. Bodugoz Senturk¹, S. Nanda², D. Bichara¹, H. Kluk³, G. Braithwaite⁴, O. K. Muratoglu¹;

¹Massachusetts Gen. Hosp., Boston, MA, ²Boston Univ., Boston, MA, ³Dartmouth Coll., Hanover, NH, ⁴Massachusetts Gen. Hosp./Harvard Med. Sch., Boston, MA.

842

Design and Fabrication of an Integrated Bi-layered Scaffold for Osteochondral Tissue Engineering

A. Galperin, R. A. Oldinski, S. J. Florczyk, J. D. Bryers, M. Zhang, M. A. Paul, B. D. Ratner;

Univ. of Washington, Seattle, WA.

843

Reduced Inflammatory Responses Of Poly(Lactide-Co-Glycolide) By Incorporating Hydroxybenzyl Alcohol Releasing Copolyoxalate

D. Lee, Y. Lee, S. Jeong, D. Hong, G. Khang;

Chonbuk Natl. Univ., Jeonju, Chonbuk, KOREA, REPUBLIC OF.

844

Tailoring Degradation Rate and Mechanical Properties of Modified Poly(ε-caprolactone)

T-Y. Shih;

Industrial Technology Res. Inst., Hsinchu 30011, TAIWAN.

845

Microstructure and Rheology of Polyhydroxyalkanoates: Influence of Valerate Content

M. Domínguez-Díaz¹, A. Flores², R. Cruz-Silva³, A. Romo-Uribe¹;

¹Inst. de Ciencias Físicas, UNAM, Cuernavaca, MEXICO, ²Inst. de Estructura de la Materia, CSIC, Madrid, SPAIN, ³Centro de Investigación en Ingeniería y Ciencias Aplicadas, UAEM, Cuernavaca, MEXICO.

846

Hydrolysable Linkers and Crosslinkers for Absorbable Polymers

N. Srivastava, R. S. Bezwada;

Bezwada BioMed., LLC, Hillsborough, NJ.

847

Effects of Addition of Transition Metal Oxides to Polymer on Growth of Human Cells

P. A. Tran¹, J. D. Jarrell², R. A. Hayda¹, C. T. Born¹;

¹Rhode Island Hosp., Providence, RI, ²Biointraface, East Greenwich, RI.

848

Viscous Polyester Terpolymers as a Short-Term Drug Delivery Platform

G. A. Winchester;

Surmodics Pharmaceuticals, Birmingham, AL.

849

In vitro Degradation Behavior of Poly(p-dioxanone) Films: Effects of Temperature on Physical Properties

E. L. Paetzell, M. Deng, R. Vetrecin;

Ethicon, Somerville, NJ.

850

Poly(Butylene Fumerate) and Poly(Butylene Fumerate)-co-(Butylene Maleate) as Biodegradable Materials for Tissue Engineering

E. L. Hedberg-Dirk¹, K. N. Cicotte¹, S. M. Dirk²;

¹Univ. of New Mexico, Albuquerque, NM, ²Sandia Natl. Lab., Albuquerque, NM.

851

Mechanical Properties of and In Vitro Response to a Novel Resorbable Biomaterial

M. Jarman-Smith¹, J. E. Wilson¹, A. Elleray¹, P. Souter², G. R. Webster³, B. Wilson³, A. Kelly⁴, L. Mulvaney-Johnson⁴, D. F. Farrar²;

¹Invibio Ltd, Thornton Cleveleys, UNITED KINGDOM, ²Smith & Nephew Res. Ctr., York, UNITED KINGDOM, ³Victrex PLC, Thornton Cleveleys, UNITED KINGDOM, ⁴Polymer IRC, Bradford Univ., Bradford, UNITED KINGDOM.

852

A Novel Polysaccharide-Derived Hydrogel with Controllable Viscosity for Adhesion Prevention

Y. Yamamoto;

Teijin Limited, Tokyo, JAPAN.

853

Study and Characterization of Telmisartan Controlled Release’s Devices using Cyclodextrins and Biodegradable Polymers

A. D. M. Gomes, A. L. A. César, I. S. Lula, R. D. Sinisterra, Sr.;

Federal Univ. of Minas Gerais, Belo Horizonte, BRAZIL.

854

Electrospinning and hemostatic properties of gelatin/zein fibrous membranes

C. Yao;

Southeast Univ., Nanjing, CHINA.

855

Enhanced Cytosolic Drug Delivery Using Fully Biodegradable Poly(Amino Oxalate) Particles

D. Lee;

Chonbuk Natl. Univ., Jeonju, Chonbuk, KOREA, REPUBLIC OF.

856

pH-Responsive Self-Healing Hydrogels Formed by Boronate-Catechol Complexation

L. He;

Northwestern Univ., Evanston, IL.

857

Self-Assembling Of Alkyl Chains in Acylated Hyaluronan

D. Smejkalova, M. Hermannova, R. Sulakova, L. Palek, V. Velebny;

Contipro C, Dolni Dobrouc, CZECH REPUBLIC.

858

Hybrid Bio/Synthetic Biomimetic Aggrecan: An Enzymatically Resistant Design Strategy

S. Sarkar¹, L. Mejias¹, C. Schauer¹, E. Vresilovic², M. Marcolongo¹;

¹Drexel Univ., Philadelphia, PA, ²Penn State Hershey Med. Ctr., Hershey, PA.

859

Synthesis And Characterization Of Temperature-Sensitive Oligo(Ethylene Glycol) Grafted Poly(L-Glutamate) Copolymers

C. He, Y. Cheng, C. Xiao, J. Ding, X. Zhuang, X. Chen;

Changchun Inst. of Applied Chemistry, Chinese Academy of Sci., Changchun, CHINA.

860

Mechanical Characterization of PVA-UHMWPE Fiber Composites for Meniscal Replacement

J. L. Holloway, S. El-Amin, N. Kelly, S. A. Maher, A. M. Lowman, G. R. Palmese;

Drexel Univ., Philadelphia, PA.

861

Amphotericin B Delivery from Antimicrobial Loaded Bone Cement is Increased by Poragens

C. Kweon¹, A. McLaren¹, C. Leon², R. Miller¹, R. McLemore¹;

¹Banner Good Samaritan Orthopaedic Residency, Phoenix, AZ, ²Arizona State Univ., Phoenix, AZ.

862

Fabrication of Mineralized Zein/Hydroxyapatite Nanofibrous Membranes

X. Li;

Southeast Univ., Nanjing, CHINA.

863

Developing Permissive Hydrogels with Physiological Osmolarity for 3D Cell Growth

X. Jin, X. Wen;

Clemson Univ.-Med. Univ. of South Carolina, Charleston, SC.

864

PLA Electrospun Fibers Incorporating Silver Nanoparticles. Morphology and Thermal Properties

H. Vargas;

Univ. Natl. Autonoma de Mexico, Cuernavaca, MEXICO.

865

Electrospun Polyhydroxyalkanoate Membranes

M. Domínguez-Díaz¹, A. Flores², R. Cruz-Silva³, A. Romo-Uribe¹;

¹Inst. de Ciencias Físicas, UNAM, Cuernavaca, MEXICO, ²Inst. de Estructura de la Materia, CSIC, Madrid, SPAIN, ³Centro de Investigación en Ingeniería y Ciencias Aplicadas, UAEM, Cuernavaca, MEXICO.

866

Biological Analysis of Newly Fabricated Nano-Porous Network on PEEK Surface

Y. Zhao¹, K. Yeung¹, H. Pan¹, J. Jiang², P. Chu², K. Luk³, K. Cheung¹;

¹Dept of Orthopaedics & Traumatology, the Univ. of Hong Kong, Hong Kong, HONG KONG, ²Dept. of Physics and Materials Sci., City Univ. of Hong Kong, Hong Kong, HONG KONG, ³Dept. of Orthopaedics & Traumatology, The Univ. of Hong Kong, Hong Kong, HONG KONG.

867

High-Throughput Screening Of PLGA Thin Films Utilizing Hydrophobic Fluorescent Dyes

S. Kumar;

Nanyang Technological Univ., Singapore, SINGAPORE.

868

A Non Free Radical, Single Step Synthesis Method for Poly(β-amino Ester) Hydrogels

D. Biswal, P. Wattamwar, A. Lyvers, T. Dziubla, J. Z. Hilt;

Univ. of Kentucky, Lexington, KY.

869

Tuning Bending Stiffness in Elastomeric Electrospun Scaffolds for Heart Valve Tissue Engineering

N. J. Amoroso, A. D'Amore, M. S. Sacks, W. R. Wagner;

Univ. of Pittsburgh, Pittsburgh, PA.

870

Use of Nylon-3 Polymer Libraries to Characterize and Control Cell-Polymer Interactions

R. Liu, S. H. Gellman, K. S. Masters;

Univ. of Wisconsin, Madison, WI.

871

Studies of Shear Stress-Dependent Cell Detachment from Temperature-Responsive Cell Culture Surfaces by Using Microfluidic Devices

Z. Tang, Y. Akiyama, K. Itoga, J. Kobayashi, T. Okano;

Inst. of Advanced BioMed. Engineering and Sci., TWIns, Tokyo Women’s Med. Univ., Tokyo, JAPAN.

872

Immobilization Of Gene Vectors On Maleic Anhydride-Grafted-Poly(D,L-Lactide-Co-Glycolide) Surfaces For Localized Gene Delivery

G. Ma, C. Song;

Peking Union Med. Coll. & Chinese Academy of Med. Sci., Tianjin, CHINA.

873

Tube-shaped Devices with Controlled Geometry for Programmed Drug Delivery

M. Park, C. Park, S. Lee, E. Cho, J. Lee, Y. Choy;

Seoul Natl. Univ., Seoul, KOREA, REPUBLIC OF.

874

Amino Acid based Polyesteramides and Polyesterurethanes: Cell Resposive Matrices for Drug Delivery

A. A. Dias¹, B. Plum¹, B. Turnell²;

¹DSM BioMed., Geleen, NETHERLANDS, ²Consultant, Oxford, UNITED KINGDOM.

876

Synthesis and Swelling Behaviors of Biodegradable pH-Sensitive Hydrogels Composed of Poly(Acrylic Acid) and Poly(L-Glutamic Acid)

X. Zhuang, X. Gao, C. Zhao, C. He, Q. Xu, X. Chen;

Changchun Inst. of Applied Chemistry, Changchun, CHINA.

877

Characterization of Polyelectrolyte-Coated Liposomes for Delivery of Estradiol

K. Bowey¹, J-F. Tanguay², M. Tabrizian¹;

¹McGill Univ., Montreal, QC, CANADA, ²Montreal Heart Inst., Montreal, QC, CANADA.

878

Limonene Epoxidation Studies in Order to Obtain Natural Monomers

A. J. Bonon, Sr.¹, D. Mandelli, Sr.², G. B. Shul'pin, Sr.³, R. Maciel, Sr.¹;

¹State Univ. of Campinas, Campinas, BRAZIL, ²Federal Univ. of ABC, Santo André, BRAZIL, ³Semenov Inst. of Chemical Physics - Russian Academy of Sci., Moscow, RUSSIAN FEDERATION.

879

Application of High-Hydrostatic Pressure Technique for the Preparation Of PVA-Heparin Hybrid Gel

J. Negishi¹, K. Nam¹, T. Kimura¹, T. Fujisato², A. Kishida¹;

¹Inst. of Biomaterials and Bioengineering, Tokyo Med. and Dental Univ., Tokyo, JAPAN, ²Osaka Inst. of Technology, Osaka, JAPAN.

880

Absorbable Microparticle Surface modification and Examination of Resultant Charge Density

C. A. Hart, J. T. Corbett, D. R. Ingram, J. M. Olbrich, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

881

Radiation Crosslinked Poly(vinyl alcohol)/Poly(vinyl pyrrolidone)/Poly(ethylene glycol) Hydrogels for Biomedical Applications

V. R. Binetti, W. Wolf, H. A. Cheng, M. Marcolongo, A. Lowman;

Drexel Univ., Philadelphia, PA.

882

Study of the Crosslinking of PHEMA Hydrogels by FTIR for Biomedical Applications

M. F. Passos, C. G. B. Dias, V. P. Bavaresco, A. Jardini, C. A. C. Zavaglia, R. Maciel;

State Univ. of Campinas, Campinas, BRAZIL.

883

Fabrication and Characterization of Synthetic Hydrogel Fibers

H. Lee, E. Cho, C. Sander, D. Burgin, E. Steele, A. Sen, J. Lee, K. Webb;

Clemson Univ., Clemson, SC.

884

Cytotoxicity of Locally Delivered Amphotericin B

S. Harmsen¹, A. McLaren¹, C. Pauken², R. McLemore¹;

¹Banner Good Samaritan Orthopaedic Residency, Phoenix, AZ, ²Arizona State Univ., Phoenix, AZ.

885

Embolization of Abdominal Aortic Aneurysm Using a Radio-Opaque Hydrogel Combining Embolic-Sclerotic Properties

A. Fatimi¹, S. Berrahmoune¹, J-M. Coutu¹, P. Chabrot², G. Soulez², S. Lerouge¹;

¹ÉTS, Montréal, QC, CANADA, ²CHUM, Radiology Dept., Montréal, QC, CANADA.

886

Controlled Release of Anti-Microbial Agents for Hospital Acquired Infection

N. Srivastava, R. S. Bezwada;

Bezwada BioMed., LLC, Hillsborough, NJ.

887

Interaction of Osteoblast-Like MG-63 Cells with Biodegradable Polyurethane Scaffolds for Cancellous Bone Graft Substitutes

J. Podporska;

Dublin City Univ., Dublin, IRELAND.

Surface Fouling, Biofilms, and Their Impacts on Medical Devices

888

Plasma Surface Modification of PEEK - Effects on Bacterial Adhesion and Co-culture with Osteoblasts In Vitro

E. T. J. Rochford¹, G. Subbiahdoss², T. F. Moriarty¹, A. H. C. Poulsson¹, H. C. van der Mei², H. J. Busscher², R. Richards¹;

¹AO Fndn., Davos Platz, SWITZERLAND, ²Univ. Med. Ctr. Groningen and Univ. of Groningen, Groningen, NETHERLANDS.

889

Elucidation of Protein Adsorption Behavior Based on Molecular Dynamics around Polymer Brush Surface

Y. Inoue, T. Nakanishi, K. Ishihara;

The Univ. of Tokyo, Tokyo, JAPAN.

890

Highly Manufacturable Anti-Fouling Surface Modification of Vascular Access Catheters

C. C. Huval, M. Bouchard, A. Deleault, J. Kaitz, J. Li, C. Loose, E. Marchese, R. Reed, L. Roth, K. Schultz, M. Skinner, H. Wang, D. Weaver, A. Weinstock, Z. Zhang;

Semprus BioSci., Cambridge, MA.

891

The Response of Pseudomonas Aeruginosa Biofilm to a Novel Glass Polyalkenoate Cement.

M. R. Towler¹, A. Coughlan¹, M. P. Ryan², N. M. Cummins²;

¹Alfred Univ., Alfred, NY, ²Univ. of Limerick, Limerick, IRELAND.

Regenerative Engineering: The Intersection of Tissue Engineering and Regenerative Biology

892

Evaluation of Biomaterials for Esophagus or Small Intestine Tissue Engineering

T. Knight, R. Payne, J. Basu, J. W. Ludlow, N. Sangha, K. Guthrie, M. Jayo, E. Rivera, D. Jain;

Tengion, Inc, Winston-Salem, NC.

893

Fibrin Targeted Block Co-polymers for the Prevention of Postsurgical Adhesions

T. D. Dziubla¹, J. M. Medley², E. Kaplan³, H. S. Oz¹, S. C. Sundararaj¹, D. A. Puleo¹;

¹Univ. of Kentucky, Lexington, KY, ²Ctr. Coll., Danville, KY, ³3Ctr. for Advanced Gynecologic Surgery, Walnut Creek, CA.

894

S1P-Induced Microvascular Remodeling is Mediated by Bone Marrow Cell Recruitment

A. O. Awojoodu¹, L. S. Anderson², S. M. Peirce¹, K. R. Lynch¹, E. A. Botchwey¹;

¹Univ. of Virginia, Charlottesville, VA, ²Lafayette Coll., Easton, PA.

895

Engineering Vascular Replacements with Elastogenic Factor-Functionalized Scaffolds in a Rat Peritoneal Cavity

C. A. Bashur, A. Ramamurthi;

Cleveland Clinic, Cleveland, OH.

896

Orchestrated Stem Cell-based Regeneration (OSCeR) for Bone Tissue Engineering

A. M. Nair, J. Shen, Y-T. Tsai, L. Tang;

The Univ. of Texas at Arlington, Arlington, TX.

897

Mechanisms of Enhanced Osteoblast Functions in the Presence of Hydroxyapatite Coated Iron Oxide Nanoparticles

N. Tran, T. J. Webster;

Brown Univ., Providence, RI.

898

Bioresorbable Polylactide Implant Promotes Tendon Ossification in the Bone Tunnel in Ligament Reconstruction Surgery

K. Ficek;

Galen Orthopedics, Bierun, POLAND.

899

Influence of Oxygen Tension in Osteogenic Differentiation of Encapsulated Stem Cells

S. Sahai, J. O. Blanchette;

Univ. of South Carolina, Columbia, SC.

900

Aloe Vera Pectin: From Extraction to Matrices for Regenerative Medicine

S. Bozzini¹, R. Gentilini¹, F. Munarin¹, P. Petrini¹, M. Scavone², L. Visai², M. C. Tanzi¹;

¹Politecnico di Milano, Milan, ITALY, ²Università di Pavia, Pavia, ITALY.

901

Sustained Release of IGF-1 from Chitosan Microparticles to Apply In Bone Regeneration

V. Mantripragada, A. C. Jayasuriya;

Univ. of Toledo, Toledo, OH.

902

Bioresponse of Mammalian Kidney to Implantation of Polymeric Materials

R. Payne, T. Knight, J. Basu, E. Rivera, N. Robbins, D. McCoy, M. Jayo, C. Halberstadt, D. Jain;

Tengion, Inc, Winston-Salem, NC.

903

Identifying Regions of Hypoxic Signaling within Three-Dimensional Stem Cell Aggregates for Engineering Cartilage

M. L. Skiles;

Univ. of South Carolina, Columbia, SC.

Scaffolds for Tissue Engineering: Successful Academia-Industry Collaborations

904

Effect of GRGDSP-Alginate in Alginate Foam for 3D Cell Culture Compared to Cells Affinity to FITC-GRGDSP

T. Andersen, C. Markussen, H. Heier-Baardson, J. Melvik, M. Dornish;

NovaMatrix/FMC BioPolymer, Sandvika, NORWAY.

905

Generation of Adipose Tissue from Adipose Derived Stem Cells in HyStem Hydrogels

S. K. Atzet;

Glycosan Biosystems, Salt Lake City, UT.

906

Biointegrative Reticulated Elastomeric Matrix for Ventral Hernia Repair

A. Datta;

Biomerix, Somerset, NJ.

907

The assessment of Bone Formation in Vitreous Carbon Foam Using the Rat Calvarial Defect Model

H. Yu¹, N. Zacharias², T. Sandid², Z. Song¹, S-Y. Yang¹, A. Chong¹, D. A. McQueen³, P. H. Wooley¹;

¹Via Christi Hlth.Hosp., Wichita, KS, ²Natl. Ctr. of Innovation for Biomaterials in Orthopaedic Res., Wichita, KS, ³Univ. of Kansas Sch. of Med., Wichita, KS.

908

In Vivo Study of a Novel AuNP-Tissue Scaffold

S. A. Grant¹, C. R. Deeken², D. A. Grant¹, S. L. Bachman¹, B. J. Ramshaw³;

¹Univ. of Missouri, Columbia, MO, ²Washington Univ., St. Louis, MO, ³Halifax Hlth., Daytona Beach, FL.

909

Engineered Synthetic Cornea with Controlled Porosity Edge Region for Biological Integration

F. B. Karp¹, S. Garty¹, M. Maginness², A. Marshall², T. T. Shen¹, B. D. Ratner¹;

¹Univ. of Washington, Seattle, WA, ²Healionics Corp., Seattle, WA.

910

Cardiomyocyte Response to Varying Composition of ECM Proteins and Stiffness on a Semi-Synthetic Hyaluronan Hydrogel

A. M. McCollough;

Glycosan Biosystems, Salt Lake City, UT.

911

Volumizing Characteristics of Dermal Fillers

B. Voigts;

Merz Aesthetics, Franksville, WI.

Industrial Solutions to Material Problems, Biomaterials and Processing Technologies for Industrial Applications

912

Non-Invasive Quantification of Plasmid Dynamics: Biofilm Formation Effect on Plasmid conjugational plasmid transfer

H. Ma;

Univ. of Washington, Seattle, WA.

913

A Novel High Strength and High Porosity Resorbable Scaffold

J. L. Krevolin, J. Liu, K. Patel, R. Dahl;

Bio2 Technologies, Woburn, MA.

914

Radiation Crosslinked Shape Memory Polymers for Biomedical Applications

W. E. Voit¹, T. Ware¹, K. Gall²;

¹The Univ. of Texas at Dallas, Richardson, TX, ²The Georgia Inst. of Technology, Atlanta, GA.

Combination Products

915

Highly Compliant Drug Eluting Absorbable Spray Bandage, An Initial Report

R. T. Pace, J. T. Corbett, J. M. Olbrich, S. D. Nagatomi, K. A. Nichter, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

916

In Vitro Antimicrobial Efficacy Testing Of A Needless Connector's Septum Which Has Been Manufactured With Silver And Chlorhexidine

B. Luchsinger, M. Schallenberger, T. Meyer;

Bacterin Intl., Belgrade, MT.

917

Evaluation of Biofilm Formation on Spinal Fixation Materials

S. Vadapalli¹, A. Agostinho², M. Harper¹, G. James²;

¹Medtronic Spinal and Biologics, Memphis, TN, ²Montana State Univ.-Bozeman, Bozeman, MT.

918

Cationic Antimicrobial Peptides Potent against Common Orthopedic Pathogens

B. Li¹, J. Noore¹, A. Noore²;

¹West Virginia Univ. Sch. of Med., Morgantown, WV, ²West Virginia Univ., Morgantown, WV.

919

A New Silicone Carbonate Polyurethane Copolymer

J. Tan, T. Strang;

St. Jude Med. CRMD, Sylmar, CA.

920

Retrieval Analyses of Dynesys® Polymeric Implants from a United States Investigational Device Exemption Study

K. Zhang¹, J. Dawson¹, M. Shen²;

¹Zimmer Spine Inc., Minneapolis, MN, ²Zimmer Inc., Warsaw, IN.

921

Development of Shape-Memory Polymer Medical Devices - From Academia to Industry

C. M. Yakacki¹, J. C. Griffis¹, K. Gall²;

¹MedShape Solutions, Atlanta, GA, ²The Georgia Inst. of Technology, Atlanta, GA.

922

Smooth Muscle Cell Response to Hydroxyapatite Coated Endovascular Stent Materials

B. H. Winn;

Clemson Univ., Clemson, SC.

Imaging Biomaterials

923

Versatile Polymer Microspheres for Injection Therapy: Aspects of X-Ray Visibility and Biofunctionalization

K. Saralidze, M. L. W. Knetsch, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.

924

Bioresorbable Microsphere Tracking In Vivo Via Encapsulated Iron Oxide Nanoparticles

T. W. Franklin-Ford, N. Shah, A. N. Raval, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.

925

Design and Synthesis of Manganese-Ligand Based Magnetic Resonance Imaging Contrast Agents

H. Ai, C. Wu;

Natl. Engineering Res. Ctr. For Biomaterials, Chengdu, Sichuan, CHINA.

926

A Multidimensional High Content Analysis System For Studying Cell-Matrix Interaction With GPU Accelerated Image Processing

Y. Pang¹, X. Wang¹, D. Lee², A. Matsumura³, H. P. Greisler⁴;

¹Illinois Inst. of Technology, Hines, IL, ²Hines VA Hosp., Hines, IL, ³Chicago Association for Res. and Ed. in Sci., Hines, IL, ⁴Loyola Univ. Med. Ctr., Hines, IL.

927

pH-Responsive Polymeric Micelle For Theranostics Of Ischemia Celebral Area

G. Gao¹, D. Kim², J. Lee³, D. Lee¹;

¹Theranostic Macromolecules Res. Ctr., Dept. of Polymer Sci. and Engineering, SungKyunKwan Univ., Suwon, KOREA, REPUBLIC OF, ²Theranostic Macromolecules Res. Ctr., Dept. of Chemical Engineering, SungKyunKwan Univ., Suwon, KOREA, REPUBLIC OF, ³Dept. of Radiology, Samsung Med. Ctr., Sch. of Med., SungKyunKwan Univ., Seoul, KOREA, REPUBLIC OF.

928

Doxorubicin-Loaded Magnetic Nanorods with Temperature-Dependent Encapsulation Behaviors

H. Kim, H. Yoo, S. Park, J. Choi, Y. Son, S. Yoon, E. Jo;

Kangwon Natl. Univ., Chuncheon, KOREA, REPUBLIC OF.

929

Multifunctional Halloysite Nanotubes for Drug Delivery and Magnetic Resonance Imaging

H. Ai, N. Ma;

Natl. Engineering Res. Ctr. For Biomaterials, Chengdu, Sichuan, CHINA.

930

Controlled Anchoring of SPIO Nanoparticles on Silica Templates as Sensitive MRI Probes

H. Ai, J. Tian;

Natl. Engineering Res. Ctr. For Biomaterials, Chengdu, Sichuan, CHINA.

931

Towards Biomimetic Tissue Phantoms for Brain Tumor Detection using Magnetic Resonance Elastography

A. M. Yousefi¹, J. A. Minton¹, C. S. Drapaca²;

¹Miami Univ., Oxford, OH, ²The Pennsylvania State Univ., University Park, PA.

932

Dielectric Spectroscopy of MDCK Cell Activity in Microfabricated Three-Dimensional Scaffolds

J. Daoud¹, K. Asami², L. Rosenberg¹, M. Tabrizian¹;

¹McGill Univ., Montreal, QC, CANADA, ²Kyoto Univ., Kyoto, JAPAN.