Con-current Oral Abstract Presentations Session 9

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Alternative Platforms for Pharmacologic Administration

310

Characterization of Hepatocytes Cultured on Micropatterned Agarose Scaffolds Crosslinked with Collagen

A. Y. Au¹, J. M. Hasenwinkel², C. G. Frondoza¹;

¹Nutramax Lab., Inc., Edgewood, MD, ²Syracuse Univ., Syracuse, NY.

311

In-Vitro Release of a Non-Steroidal Anti-Inflammatory from Daily Wear Therapeutic Contact Lenses

A. Tieppo, K. M. Pate, M. E. Byrne;

Biomimetic & Biohybrid Materials, BioMed. Devices, and Drug Delivery Lab., Dept. of Chemical Engineering, Auburn Univ., Auburn, AL.

312

Doxorubicin-Filled Radiopaque Microspheres for Improved Chemo-Embolization of Hepatocellular Carcinomas.

M. L. W. Knetsch, K. Saralidze, C. Mostert, R. van Berkel, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.

313

Absorbable Synthetic Bone Wax for the Localized Delivery of Therapeutic Agents

K. D. Gray, Jr., J. M. Olbrich, M. S. Taylor, J. T. Corbett, W. S. W. Shalaby, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.

314

Platelet-Targeted Nanoconstructs for Site-Specific Drug Delivery in Vascular Disease

C. Modery, M. Ravikumar, A. Sen Gupta PhD;

Case Western Reserve Univ., Cleveland, OH.

315

Surface Modification of Stent Material Using Self-Assembled Monolayers for Sustained Delivery of Paclitaxel

G. Mani;

Univ. of South Dakota, Sioux Falls, SD.

316

Injectable, Environmentally-Responsive Microspheres for Growth Factor Delivery

T. W. Franklin-Ford, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.

317

Triggered Molecule Release from Light-Responsive Polymer/Nanorod Composites

K. C. Hribar, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

Biomaterial Stem Cell Interactions

318

Combinatorial 3D Hydrogels for Stem Cell Niche Optimization towards Bone Differentiation

F. Yang, M. Nii, G. Imanbayev;

Stanford Univ., Stanford, CA.

319

Spatially Controlled Mechanics Modulate Stem Cells in Sequentially Crosslinked Macroporous Hydrogels

R. A. Marklein, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

320

Laminin-Based Nanofibers to Replace Feeder Layers for Embryonic Stem Cell Culture

T. Wang, R. A. Neal, E. A. Botchwey;

Univ. of Virginia, Charlottesville, VA.

321

Synthetic Peptide Surfaces for Maintenance and Expansion of Human Embryonic Stem Cells

R. Gupta, L. E. Little, D. V. Schaffer, K. E. Healy;

Univ. of California, Berkeley, CA.

322

Characterization of Growth Factor Release and Bioactivity in Electrospun Polymer-Ceramic Composites

T. Briggs, T. L. Arinzeh;

New Jersey Inst. of Technology, Newark, NJ.

323

Sequestration of Endogenous TGF-ß for Directed Differentiation of Mesenchyal Stem Cells

S. B. Anderson, K. S. Anseth;

Howard Hughes Med. Inst., Univ. of Colorado, Boulder, CO.

324

A Multilayer Hydrogel of Unique Material Compositions Direct a Single Progenitor Cell Population into Zonally Organized and Mechanically Relevant Articular Cartilage

L. H. Nguyen, N. Saxena, K. Roy;

Univ. of Texas at Austin, Austin, TX.

325

Multiplex Biomaterial Matrix Cues Modulate Cancerous Progression of Adult Stem Cells

S. W. Crowder, A. L. Zachman, Y. Liang, H-J. Sung;

Vanderbilt Univ., Nashville, TN.

Polymeric Biomaterials - Synthesis, Characterization, Processing and Fabrication for Biomedical Applications

326

Combinatorial, High-Throughput Synthesis of Core-shell Nanoparticles for siRNA Delivery

D. J. Siegwart, K. Whitehead, S. Jiang, M. Ma, H. Cheng, G. Sahay, A. Vegas, P. Fenton, K. Love, C. Levins, R. Langer, D. Anderson;

Massachusetts Inst. of Technology, Cambridge, MA.

327

A Cross-linking Polymer System for Cerebral Aneurysm Embolization: Formulation, Characterization, and Testing

C. Riley¹, W. Bichard², M. C. Preul², B. L. Vernon¹;

¹Arizona State Univ., Tempe, AZ, ²Barrow Neurological Inst., Phoenix, AZ.

328

In Situ Forming Poly(Ethylene Glycol)-Based Hydrogels Via Metal-Free Tiol-Maleimide Click Chemistry

Y. Fu¹, W. J. Kao²;

¹Sch. of Pharmacy, Madison, WI, ²Sch. of Pharmacy, Dept. of BioMed. Engineering, Dept. of Surgery, Madison, WI.

329

Highly Tunable Degradable Elastomers for Medical Applications

M. Nunes-Pereira¹, D. Sarkar¹, S. Mureli¹, S. Lawes¹, L. Ferreira², J. M. Karp¹;

¹Brigham's and Women Hosp., Harvard Med. Sch., Cambridge, MA, ²Biocant and Ctr. for NeuroSci. and Cell Biology, Univ. of Coimbra, Coimbra, PORTUGAL.

330

Triple Shape Memory Polymers Based on Self-Complimentary Hydrogen

T. Ware;

The Univ. of Texas at Dallas, Richardson, TX.

331

Multi-Response Strategies to Modulate Burst Degradation and Release from Nanoparticles

A. Almutairi;

Univ. of California, La Jolla, CA.

332

Novel Polyisobutylene-Based Nanocomposites as Promising Biomaterials

G. Lim¹, S. Porosky¹, Q. Wang¹, M. M. Evancho-Chapman², S. P. Schmidt², J. E. Puskas¹;

¹Dept. of Polymer Sci., Akron, OH, ²Summa Hlth.System, Akron, OH.

333

The Effect of Moisture on the Physical Properties of Polyurethane Shape Memory Polymer Foams

Y-J. Yu¹, K. Hearon¹, T. S. Wilson², D. J. Maitland¹;

¹TEXAS A&M Univ., 3120 TAMU College Station, TX, ²Lawrence Livermore Natl. Lab., Livermore, CA.

The Art of Falling Apart: Exploiting Biomaterial Degradation

334

Does Crystallinity Affect Polymer Degradation Rates?

S. Lyu, J. Zhang, B. pudil, D. Untereker;

Medtronic Inc, Minneapolis, MN.

335

Tunable Degradation and In Vivo Imaging of Poly(β-amino ester) Networks for Controlled Release Applications

D. Safranski¹, D. Weiss², J. Clark², W. R. Taylor², K. Gall¹;

¹Georgia Inst. of Technology, Atlanta, GA, ²Emory Univ., Atlanta, GA.

336

Degradation Impacts Chondrocyte Matrix Production in Dynamically Loaded Poly(ethylene glycol)-based Hydrogels

J. J. Roberts, G. D. Nicodemus, E. C. Greenwald, S. J. Bryant;

Univ. of Colorado at Boulder, Boulder, CO.

337

Cytocompatiliby and Optimization of Cardiomyocytes on Poly Lactic-Co-Glycolic Acid Carbon Nanofiber Materials

D. A. Stout, J. Yoo, T. J. Webster;

Brown Univ., Providence, RI.

338

Degradable Elastin-Based Biomaterials as Scaffolds for Multilayered, Aligned Myoblasts

D. Sengupta, S. Heilshorn;

Stanford Univ., Stanford, CA.

339

Influence of Injectable Hyaluronic Acid Hydrogel Degradation Behavior on Myocardial Infarct Repair

E. Tous, J. L. Ifkovits, K. Koomalsingh, J. H. Gorman, R. C. Gorman, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

340

Biodegradable Metal Technologies for Cardiovascular Stent Application

C. Z. Deng¹, J. D. Edick¹, P. G. Edelman¹, T. Scheuermann²;

¹Boston Scientific, Maple Grove, MN, ²Boston Scientific, Munich, GERMANY.

341

Enzyme-Sensitive Glues Allow for Sequential Separation & Recovery of Viable Cell Populations after 3D Co-Culture

N. C. Bloodworth, T. M. Hammoudi, P. J. Yang, H. Lu, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.