Con-current Oral Abstract Presentations Session 9

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Alternative Platforms for Pharmacologic Administration


Characterization of Hepatocytes Cultured on Micropatterned Agarose Scaffolds Crosslinked with Collagen

A. Y. Au1, J. M. Hasenwinkel2, C. G. Frondoza1;

1Nutramax Lab., Inc., Edgewood, MD, 2Syracuse Univ., Syracuse, NY.


In-Vitro Release of a Non-Steroidal Anti-Inflammatory from Daily Wear Therapeutic Contact Lenses

A. Tieppo, K. M. Pate, M. E. Byrne;

Biomimetic & Biohybrid Materials, BioMed. Devices, and Drug Delivery Lab., Dept. of Chemical Engineering, Auburn Univ., Auburn, AL.


Doxorubicin-Filled Radiopaque Microspheres for Improved Chemo-Embolization of Hepatocellular Carcinomas.

M. L. W. Knetsch, K. Saralidze, C. Mostert, R. van Berkel, L. H. Koole;

Maastricht Univ., Maastricht, NETHERLANDS.


Absorbable Synthetic Bone Wax for the Localized Delivery of Therapeutic Agents

K. D. Gray, Jr., J. M. Olbrich, M. S. Taylor, J. T. Corbett, W. S. W. Shalaby, S. W. Shalaby;

Poly-Med, Inc., Anderson, SC.


Platelet-Targeted Nanoconstructs for Site-Specific Drug Delivery in Vascular Disease

C. Modery, M. Ravikumar, A. Sen Gupta PhD;

Case Western Reserve Univ., Cleveland, OH.


Surface Modification of Stent Material Using Self-Assembled Monolayers for Sustained Delivery of Paclitaxel

G. Mani;

Univ. of South Dakota, Sioux Falls, SD.


Injectable, Environmentally-Responsive Microspheres for Growth Factor Delivery

T. W. Franklin-Ford, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.


Triggered Molecule Release from Light-Responsive Polymer/Nanorod Composites

K. C. Hribar, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.

Biomaterial Stem Cell Interactions


Combinatorial 3D Hydrogels for Stem Cell Niche Optimization towards Bone Differentiation

F. Yang, M. Nii, G. Imanbayev;

Stanford Univ., Stanford, CA.


Spatially Controlled Mechanics Modulate Stem Cells in Sequentially Crosslinked Macroporous Hydrogels

R. A. Marklein, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.


Laminin-Based Nanofibers to Replace Feeder Layers for Embryonic Stem Cell Culture

T. Wang, R. A. Neal, E. A. Botchwey;

Univ. of Virginia, Charlottesville, VA.


Synthetic Peptide Surfaces for Maintenance and Expansion of Human Embryonic Stem Cells

R. Gupta, L. E. Little, D. V. Schaffer, K. E. Healy;

Univ. of California, Berkeley, CA.


Characterization of Growth Factor Release and Bioactivity in Electrospun Polymer-Ceramic Composites

T. Briggs, T. L. Arinzeh;

New Jersey Inst. of Technology, Newark, NJ.


Sequestration of Endogenous TGF-ß for Directed Differentiation of Mesenchyal Stem Cells

S. B. Anderson, K. S. Anseth;

Howard Hughes Med. Inst., Univ. of Colorado, Boulder, CO.


A Multilayer Hydrogel of Unique Material Compositions Direct a Single Progenitor Cell Population into Zonally Organized and Mechanically Relevant Articular Cartilage

L. H. Nguyen, N. Saxena, K. Roy;

Univ. of Texas at Austin, Austin, TX.


Multiplex Biomaterial Matrix Cues Modulate Cancerous Progression of Adult Stem Cells

S. W. Crowder, A. L. Zachman, Y. Liang, H-J. Sung;

Vanderbilt Univ., Nashville, TN.

Polymeric Biomaterials - Synthesis, Characterization, Processing and Fabrication for Biomedical Applications


Combinatorial, High-Throughput Synthesis of Core-shell Nanoparticles for siRNA Delivery

D. J. Siegwart, K. Whitehead, S. Jiang, M. Ma, H. Cheng, G. Sahay, A. Vegas, P. Fenton, K. Love, C. Levins, R. Langer, D. Anderson;

Massachusetts Inst. of Technology, Cambridge, MA.


A Cross-linking Polymer System for Cerebral Aneurysm Embolization: Formulation, Characterization, and Testing

C. Riley1, W. Bichard2, M. C. Preul2, B. L. Vernon1;

1Arizona State Univ., Tempe, AZ, 2Barrow Neurological Inst., Phoenix, AZ.


In Situ Forming Poly(Ethylene Glycol)-Based Hydrogels Via Metal-Free Tiol-Maleimide Click Chemistry

Y. Fu1, W. J. Kao2;

1Sch. of Pharmacy, Madison, WI, 2Sch. of Pharmacy, Dept. of BioMed. Engineering, Dept. of Surgery, Madison, WI.


Highly Tunable Degradable Elastomers for Medical Applications

M. Nunes-Pereira1, D. Sarkar1, S. Mureli1, S. Lawes1, L. Ferreira2, J. M. Karp1;

1Brigham's and Women Hosp., Harvard Med. Sch., Cambridge, MA, 2Biocant and Ctr. for NeuroSci. and Cell Biology, Univ. of Coimbra, Coimbra, PORTUGAL.


Triple Shape Memory Polymers Based on Self-Complimentary Hydrogen

T. Ware;

The Univ. of Texas at Dallas, Richardson, TX.


Multi-Response Strategies to Modulate Burst Degradation and Release from Nanoparticles

A. Almutairi;

Univ. of California, La Jolla, CA.


Novel Polyisobutylene-Based Nanocomposites as Promising Biomaterials

G. Lim1, S. Porosky1, Q. Wang1, M. M. Evancho-Chapman2, S. P. Schmidt2, J. E. Puskas1;

1Dept. of Polymer Sci., Akron, OH, 2Summa Hlth.System, Akron, OH.


The Effect of Moisture on the Physical Properties of Polyurethane Shape Memory Polymer Foams

Y-J. Yu1, K. Hearon1, T. S. Wilson2, D. J. Maitland1;

1TEXAS A&M Univ., 3120 TAMU College Station, TX, 2Lawrence Livermore Natl. Lab., Livermore, CA.

The Art of Falling Apart: Exploiting Biomaterial Degradation


Does Crystallinity Affect Polymer Degradation Rates?

S. Lyu, J. Zhang, B. pudil, D. Untereker;

Medtronic Inc, Minneapolis, MN.


Tunable Degradation and In Vivo Imaging of Poly(β-amino ester) Networks for Controlled Release Applications

D. Safranski1, D. Weiss2, J. Clark2, W. R. Taylor2, K. Gall1;

1Georgia Inst. of Technology, Atlanta, GA, 2Emory Univ., Atlanta, GA.


Degradation Impacts Chondrocyte Matrix Production in Dynamically Loaded Poly(ethylene glycol)-based Hydrogels

J. J. Roberts, G. D. Nicodemus, E. C. Greenwald, S. J. Bryant;

Univ. of Colorado at Boulder, Boulder, CO.


Cytocompatiliby and Optimization of Cardiomyocytes on Poly Lactic-Co-Glycolic Acid Carbon Nanofiber Materials

D. A. Stout, J. Yoo, T. J. Webster;

Brown Univ., Providence, RI.


Degradable Elastin-Based Biomaterials as Scaffolds for Multilayered, Aligned Myoblasts

D. Sengupta, S. Heilshorn;

Stanford Univ., Stanford, CA.


Influence of Injectable Hyaluronic Acid Hydrogel Degradation Behavior on Myocardial Infarct Repair

E. Tous, J. L. Ifkovits, K. Koomalsingh, J. H. Gorman, R. C. Gorman, J. A. Burdick;

Univ. of Pennsylvania, Philadelphia, PA.


Biodegradable Metal Technologies for Cardiovascular Stent Application

C. Z. Deng1, J. D. Edick1, P. G. Edelman1, T. Scheuermann2;

1Boston Scientific, Maple Grove, MN, 2Boston Scientific, Munich, GERMANY.


Enzyme-Sensitive Glues Allow for Sequential Separation & Recovery of Viable Cell Populations after 3D Co-Culture

N. C. Bloodworth, T. M. Hammoudi, P. J. Yang, H. Lu, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.